#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:60924" uniprotkb:P00519 intact:EBI-20725289 intact:EBI-375543|uniprotkb:Q13869|uniprotkb:Q13870|uniprotkb:Q16133|uniprotkb:Q45F09|ensembl:ENSP00000323315|uniprotkb:A3KFJ3|uniprotkb:Q17R61|intact:EBI-1550796 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:abl1_human(display_long)|uniprotkb:Abelson tyrosine-protein kinase 1(gene name synonym)|uniprotkb:ABL1(gene name)|psi-mi:ABL1(display_short)|uniprotkb:ABL(gene name synonym)|uniprotkb:JTK7(gene name synonym)|uniprotkb:Abelson murine leukemia viral oncogene homolog 1(gene name synonym)|uniprotkb:Proto-oncogene c-Abl(gene name synonym)|uniprotkb:p150(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-20725293|imex:IM-26494-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_005148.2|refseq:NP_009297.2|ensembl:ENSG00000097007(gene)|ensembl:ENST00000318560(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019905"(syntaxin binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030035"(microspike assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002322"(B cell proliferation involved in immune response)|go:"GO:0002333"(transitional one stage B cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0038191"(neuropilin binding)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045580"(regulation of T cell differentiation)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048668"(collateral sprouting)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071103"(DNA conformation change)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072359"(circulatory system development)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090135"(actin filament branching)|go:"GO:0098794"(postsynapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1900275"(negative regulation of phospholipase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903053"(regulation of extracellular matrix organization)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904528"(positive regulation of microtubule binding)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1905244"(regulation of modification of synaptic structure)|go:"GO:1905555"(positive regulation of blood vessel branching)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR033221|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|mint:P00519|rcsb pdb:1AB2|rcsb pdb:1ABL|rcsb pdb:2HIW|rcsb pdb:2HYY|rcsb pdb:2HZ0|rcsb pdb:2HZ4|rcsb pdb:2HZI|rcsb pdb:2O88|rcsb pdb:2V7A|rcsb pdb:3CS9|rcsb pdb:3EG0|rcsb pdb:3EG1|rcsb pdb:3EG2|rcsb pdb:3EG3|rcsb pdb:3EGU|rcsb pdb:3K2M|rcsb pdb:3PYY|rcsb pdb:3QRI|rcsb pdb:3QRJ|rcsb pdb:3QRK|rcsb pdb:3T04|rcsb pdb:3UE4|rcsb pdb:3UYO|rcsb pdb:4J9B|rcsb pdb:4J9C|rcsb pdb:4J9D|rcsb pdb:1AWO|rcsb pdb:1BBZ|rcsb pdb:1JU5|rcsb pdb:1OPL|rcsb pdb:1ZZP|rcsb pdb:2ABL|rcsb pdb:2E2B|rcsb pdb:2F4J|rcsb pdb:2FO0|rcsb pdb:4J9E|rcsb pdb:2G1T|rcsb pdb:4J9F|rcsb pdb:2G2F|rcsb pdb:2G2H|rcsb pdb:4J9G|rcsb pdb:2G2I|rcsb pdb:4J9H|rcsb pdb:2GQG|rcsb pdb:4J9I|rcsb pdb:4JJB|rcsb pdb:4JJC|rcsb pdb:4JJD|rcsb pdb:4TWP|rcsb pdb:4WA9|rcsb pdb:4XEY|rcsb pdb:4YC8|rcsb pdb:4ZOG|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5HU9|rcsb pdb:5MO4|rcsb pdb:5NP2|rcsb pdb:5OAZ|rcsb pdb:6AMV|rcsb pdb:6AMW|rcsb pdb:6BL8|rcsb pdb:6NPE|rcsb pdb:6NPU|rcsb pdb:6NPV|rcsb pdb:6XR6|rcsb pdb:6XR7|rcsb pdb:6XRG|rcsb pdb:7CC2|rcsb pdb:7DT2|reactome:R-HSA-2029482|reactome:R-HSA-428890|reactome:R-HSA-525793|reactome:R-HSA-5663213|reactome:R-HSA-5685938|reactome:R-HSA-5693565|reactome:R-HSA-69231|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-9664422|reactome:R-HSA-983231|dip:DIP-1042N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:t7dT+fWrrK2QaWF4U0HQaVgHKUc9606 - false biotin tag:?-?|tag:?-? his tag:n-n|mutation with no effect:253-253|mutation with no effect:315-315|mutation with no effect:255-255|mutation with no effect:250-250 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:P53350 intact:EBI-2566560 intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432384|imex:IM-26494-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:fBOK366hV6mDprx9IWhz43gPcJE9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:P23229-2 intact:EBI-2566560 intact:EBI-21518201 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:p232292(display_long)|uniprotkb:ITGA6(gene name)|psi-mi:ITGA6(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432391|imex:IM-26494-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) uniprotkb:P23229-2(isoform-parent) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:BfxzrsGYRS882e6gvqqEtxAJrdY9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q16836 intact:EBI-2566560 intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432401|imex:IM-26494-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3 - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q14722-1 intact:EBI-2566560 intact:EBI-22197468|ensembl:ENSP00000419952 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:q14722-1(display_long)|uniprotkb:"K(+) channel subunit beta-1"(gene name synonym)|uniprotkb:Kv-beta-1(gene name synonym)|uniprotkb:KCNAB1(gene name)|psi-mi:KCNAB1(display_short)|uniprotkb:KCNA1B(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432411|imex:IM-26494-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) intact:EBI-1642508(isoform-parent)|ensembl:ENSG00000169282(gene)|ensembl:ENST00000490337(transcript) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:Er/E2csvNMFtZmI5s64uce21dcM9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q9BRJ7-1 intact:EBI-2566560 intact:EBI-25432418|ensembl:ENSP00000306670 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:q9brj7-1(display_long)|uniprotkb:Protein syndesmos(gene name synonym)|uniprotkb:NUDT16-like protein 1(gene name synonym)|uniprotkb:NUDT16L1(gene name)|psi-mi:NUDT16L1(display_short)|uniprotkb:SDOS(gene name synonym)|uniprotkb:TIRR(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432426|imex:IM-26494-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) ensembl:ENSG00000168101(gene)|ensembl:ENST00000304301(transcript)|intact:EBI-2949792(isoform-parent) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:OvI5o5ShGCpxBO6jQL9oUZTaXLk9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:P48729-1 intact:EBI-2566560 intact:EBI-10106282|ensembl:ENSP00000367074 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:p48729-1(display_long)|uniprotkb:CK1(gene name synonym)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432434|imex:IM-26494-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) intact:EBI-1383726(isoform-parent)|ensembl:ENSG00000113712(gene)|ensembl:ENST00000377843(transcript) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q13057 intact:EBI-2566560 intact:EBI-745967|uniprotkb:Q6GS23|uniprotkb:Q8NBM7|uniprotkb:Q8NEW1|uniprotkb:Q8WXD4|uniprotkb:Q9NRM3|uniprotkb:B2RA78|uniprotkb:B4DLU0|ensembl:ENSP00000377406|ensembl:ENSP00000393564 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:coasy_human(display_long)|uniprotkb:NBP(gene name synonym)|uniprotkb:POV-2(gene name synonym)|uniprotkb:COASY(gene name)|psi-mi:COASY(display_short)|uniprotkb:PSEC0106(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432520|imex:IM-26494-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_001035994.1|refseq:NP_001035997.2|refseq:NP_079509.5|refseq:XP_011523602.1|ensembl:ENSG00000068120(gene)|ensembl:ENST00000393818(transcript)|ensembl:ENST00000421097(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0004595"(pantetheine-phosphate adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR027417|reactome:R-HSA-196783|refseq:XP_006722179.1|refseq:XP_016880657.1 - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:yMK1IODpj01+JZsNsayJCgEHpyo9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:O15111 intact:EBI-2566560 intact:EBI-81249|uniprotkb:O14666|uniprotkb:Q13132|uniprotkb:Q5W0I4|uniprotkb:Q92467|ensembl:ENSP00000359424|intact:EBI-28970970 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:ikka_human(display_long)|uniprotkb:CHUK(gene name)|psi-mi:CHUK(display_short)|uniprotkb:IKKA(gene name synonym)|uniprotkb:TCF16(gene name synonym)|uniprotkb:I-kappa-B kinase 1(gene name synonym)|uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)|uniprotkb:Transcription factor 16(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432528|imex:IM-26494-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_001269.3|ensembl:ENSP00000359424|ensembl:ENSG00000213341(gene)|ensembl:ENST00000370397(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0010034"(response to acetate)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022007|interpro:IPR041185|mint:O15111|rcsb pdb:3BRT|rcsb pdb:5EBZ|rcsb pdb:5TQW|rcsb pdb:5TQX|rcsb pdb:5TQY|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-198323|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5674400|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|dip:DIP-27526N - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:FVB/gXjSBTB9hdq9pycQogxesms9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q8IUC0 intact:EBI-2566560 intact:EBI-11735920|uniprotkb:Q14D20|uniprotkb:Q3LI79|ensembl:ENSP00000347635 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:kr131_human(display_long)|uniprotkb:KRTAP13-1(gene name)|psi-mi:KRTAP13-1(display_short)|uniprotkb:KAP13.1(gene name synonym)|uniprotkb:KRTAP13.1(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 13.1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432538|imex:IM-26494-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_853630.2|ensembl:ENSG00000198390(gene)|ensembl:ENST00000355459(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567 - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:fOucuUNuXgKm5HWBY5kuka8kvDI9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q13153-1 intact:EBI-2566560 intact:EBI-15628682|ensembl:ENSP00000348696 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:q13153-1(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432546|imex:IM-26494-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) intact:EBI-1307(isoform-parent)|uniprotkb:Q13153-1(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:O75582-1 intact:EBI-2566560 intact:EBI-16135973|ensembl:ENSP00000479667 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:o75582-1(display_long)|uniprotkb:RPS6KA5(gene name)|psi-mi:RPS6KA5(display_short)|uniprotkb:MSK1(gene name synonym)|uniprotkb:90 kDa ribosomal protein S6 kinase 5(gene name synonym)|uniprotkb:Nuclear mitogen- and stress-activated protein kinase 1(gene name synonym)|uniprotkb:RSK-like protein kinase(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432554|imex:IM-26494-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) intact:EBI-73869(isoform-parent)|ensembl:ENSG00000100784(gene)|ensembl:ENST00000614987(transcript) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:8W2PRa/aVTLxiBJEbbXoebPqlco9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:P17948-1 intact:EBI-2566560 intact:EBI-25432562|ensembl:ENSP00000282397 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:p17948-1(display_long)|uniprotkb:Fms-like tyrosine kinase 1(gene name synonym)|uniprotkb:Tyrosine-protein kinase FRT(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor FLT(gene name synonym)|uniprotkb:Vascular permeability factor receptor(gene name synonym)|uniprotkb:Flt1(isoform synonym)|uniprotkb:FLT1(gene name)|psi-mi:FLT1(display_short)|uniprotkb:FLT(gene name synonym)|uniprotkb:FRT(gene name synonym)|uniprotkb:VEGFR1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432573|imex:IM-26494-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) ensembl:ENSG00000102755(gene)|ensembl:ENST00000282397(transcript)|intact:EBI-1026718(isoform-parent) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:AfSO/WFuXISaK/PbB/s2Vv+vLFE9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:O95819-4 intact:EBI-2566560 intact:EBI-25432582|ensembl:ENSP00000489579 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:o95819-4(display_long)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym)|uniprotkb:HGK-S(isoform synonym)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432593|imex:IM-26494-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) ensembl:ENSG00000071054(gene)|ensembl:ENST00000634702(transcript)|intact:EBI-2511133(isoform-parent) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:ahcRoxwIC16DMz3i/N4/+VkrdHQ9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q5JSZ5 intact:EBI-2566560 intact:EBI-744891|uniprotkb:Q66VZ2|uniprotkb:Q9H683|uniprotkb:Q5JSZ7|uniprotkb:O60270|intact:EBI-2512629|intact:EBI-947989|uniprotkb:Q68CR0|intact:EBI-2559356|uniprotkb:Q96EI9|ensembl:ENSP00000508005|ensembl:ENSP00000508048 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:prc2b_human(display_long)|uniprotkb:PRRC2B(gene name)|psi-mi:PRRC2B(display_short)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:KIAA0515(gene name synonym)|uniprotkb:BAT2L(gene name synonym)|uniprotkb:BAT2L1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432601|imex:IM-26494-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_037450.2|ensembl:ENST00000682501|ensembl:ENSP00000508073|ensembl:ENSP00000508048|ensembl:ENSP00000508005|ensembl:ENSG00000288701(gene)|ensembl:ENST00000683519(transcript)|ensembl:ENST00000684596(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q5JSZ5 - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:N1MgJl3k+WJTF+XUf5VFIB06B909606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q9NSB8-2 intact:EBI-2566560 intact:EBI-12017090|ensembl:ENSP00000407634 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:q9nsb8-2(display_long)|uniprotkb:HOMER2(gene name)|psi-mi:HOMER2(display_short)|uniprotkb:Cupidin(gene name synonym)|uniprotkb:2a(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432609|imex:IM-26494-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) intact:EBI-2126733(isoform-parent)|uniprotkb:Q9NSB8-2(isoform-parent)|ensembl:ENSG00000103942(gene)|ensembl:ENST00000450735(transcript) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:RVkMDQqia2rereKjtYoS/JsoQVA9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q8TAE8 intact:EBI-2566560 intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432617|imex:IM-26494-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5 - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:P48730-2 intact:EBI-2566560 intact:EBI-9087876|ensembl:ENSP00000376146 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:p48730-2(display_long)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432625|imex:IM-26494-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) intact:EBI-751621(isoform-parent)|ensembl:ENSG00000141551(gene)|ensembl:ENST00000392334(transcript)|uniprotkb:P48730-2(isoform-parent) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:DKYeQTtdg+u5Gm9wscDkiTs7Blg9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q9P270 intact:EBI-2566560 intact:EBI-3959887|uniprotkb:A8K4P1|uniprotkb:Q8N5R3|ensembl:ENSP00000264313 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:slai2_human(display_long)|uniprotkb:SLAIN2(gene name)|psi-mi:SLAIN2(display_short)|uniprotkb:KIAA1458(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432633|imex:IM-26494-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_065897.1|ensembl:ENSG00000109171(gene)|ensembl:ENST00000264313(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR026179|mint:Q9P270|rcsb pdb:3RDV - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:r8OlU6BASEpehSYkbA9b3F3q5go9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q7Z5V6 intact:EBI-2566560 intact:EBI-4311771|uniprotkb:Q96M77|uniprotkb:Q4G0P4|ensembl:ENSP00000344140 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:ppr32_human(display_long)|uniprotkb:PPP1R32(gene name)|psi-mi:PPP1R32(display_short)|uniprotkb:C11orf66(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432641|imex:IM-26494-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_001164224.1|refseq:NP_659454.2|ensembl:ENSG00000162148(gene)|ensembl:ENST00000338608(transcript)|go:"GO:0019902"(phosphatase binding)|go:"GO:0036064"(ciliary basal body)|interpro:IPR031410 - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:oyyMjHlrqnpkoH72H6ONofxNIIw9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q15067-2 intact:EBI-2566560 intact:EBI-11084968|ensembl:ENSP00000293217 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:q15067-2(display_long)|uniprotkb:ACOX(gene name synonym)|uniprotkb:Palmitoyl-CoA oxidase(gene name synonym)|uniprotkb:Straight-chain acyl-CoA oxidase(gene name synonym)|uniprotkb:ACOX1b(isoform synonym)|uniprotkb:SCOX-exon 3II(isoform synonym)|uniprotkb:ACOX1(gene name)|psi-mi:ACOX1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432649|imex:IM-26494-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) intact:EBI-3048535(isoform-parent)|ensembl:ENSG00000161533(gene)|ensembl:ENST00000293217(transcript)|uniprotkb:Q15067-2(isoform-parent) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:bV7YE+YZKeqSWyBJ0CHwUX20Ylw9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:O96013-1 intact:EBI-2566560 intact:EBI-15866280|ensembl:ENSP00000351049|ensembl:ENSP00000353625|ensembl:ENSP00000469413 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:o96013-1(display_long)|uniprotkb:PAK4(gene name)|psi-mi:PAK4(display_short)|uniprotkb:KIAA1142(gene name synonym)|uniprotkb:p21-activated kinase 4(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432657|imex:IM-26494-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) ensembl:ENSG00000130669(gene)|ensembl:ENST00000358301(transcript)|ensembl:ENST00000360442(transcript)|ensembl:ENST00000593690(transcript)|intact:EBI-713738(isoform-parent) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:8i8hHt/Taj+czkueFRAMhdiMkYw9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:O43809 intact:EBI-2566560 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432665|imex:IM-26494-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q9HB63 intact:EBI-2566560 intact:EBI-743459|ensembl:ENSP00000340998|uniprotkb:Q658K9|uniprotkb:Q7L3F1|uniprotkb:Q7L9D6|uniprotkb:Q7Z5B6|uniprotkb:Q9BZP1|uniprotkb:Q9NT44|uniprotkb:Q9P133|uniprotkb:B2RNC2 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:net4_human(display_long)|uniprotkb:Beta-netrin(gene name synonym)|uniprotkb:Hepar-derived netrin-like protein(gene name synonym)|uniprotkb:NTN4(gene name)|psi-mi:NTN4(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432675|imex:IM-26494-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|ensembl:ENSG00000074527(gene)|ensembl:ENST00000343702(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043237"(laminin-1 binding)|interpro:IPR035811|reactome:R-HSA-3000171|reactome:R-HSA-373752|go:"GO:0043256"(laminin complex)|go:"GO:0060668"(regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001134(Netrin, C-terminal)|refseq:NP_067052.2|refseq:NP_001316629.1|refseq:NP_001316630.1|refseq:NP_001316631.1|dip:DIP-46274N - - - figure legend:Table 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:Wiq3R27SFsSneLrCDSpL19glpxE9606 - false biotin tag:?-? his tag:c-c|sufficient binding region:1-628 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:O08721 intact:EBI-2566560 intact:EBI-15755467 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:unc5a_rat(display_long)|uniprotkb:Unc5a(gene name)|psi-mi:Unc5a(display_short)|uniprotkb:Unc5h1(gene name synonym)|uniprotkb:Protein unc-5 homolog 1(gene name synonym)|uniprotkb:Protein unc-5 homolog A(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432685|imex:IM-26494-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0045121"(membrane raft)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042155|reactome:R-RNO-373752|refseq:NP_071542.1|dip:DIP-60742N|rgd:621755 - - - figure legend:Table 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:h4ItFf0FHtTxXGbQ/PyIy1TQq5E10116 - false biotin tag:?-? fc-igg1:c-c|sufficient binding region:26-358 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q9H3T3 intact:EBI-2566560 intact:EBI-25432706|ensembl:ENSP00000467290|ensembl:ENSP00000503414|uniprotkb:A5PKU4|uniprotkb:F6IB19|uniprotkb:Q9NRK9 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:sem6b_human(display_long)|uniprotkb:Semaphorin-Z(gene name synonym)|uniprotkb:UNQ1907/PRO4353(orf name)|uniprotkb:SEMA6B(gene name)|psi-mi:SEMA6B(display_short)|uniprotkb:SEMAN(gene name synonym)|uniprotkb:SEMAZ(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432701|imex:IM-26494-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) ensembl:ENSG00000167680(gene)|ensembl:ENST00000586582(transcript)|ensembl:ENST00000676793(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027231|interpro:IPR036352|refseq:NP_115484.2 - - - figure legend:Table 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:HcJG/zQjP5iQEhU4UWxA+5+1d649606 - false biotin tag:?-? sufficient binding region:26-603|fc-igg1:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:P52797 intact:EBI-2566560 intact:EBI-722730|uniprotkb:Q0VGC9|uniprotkb:Q5SR70|uniprotkb:D3DV85|uniprotkb:B7ZAD3|intact:EBI-28970463|ensembl:ENSP00000357393 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:efna3_human(display_long)|uniprotkb:EPH-related receptor tyrosine kinase ligand 3(gene name synonym)|uniprotkb:EHK1 ligand(gene name synonym)|uniprotkb:EFL-2(gene name synonym)|uniprotkb:EFNA3(gene name)|psi-mi:EFNA3(display_short)|uniprotkb:EFL2(gene name synonym)|uniprotkb:EPLG3(gene name synonym)|uniprotkb:LERK3(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432741|imex:IM-26494-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_004943.1|ensembl:ENSP00000357393|ensembl:ENSG00000143590(gene)|ensembl:ENST00000368408(transcript)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007411"(axon guidance)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034252|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665 - - - figure legend:Table 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:KgSgyIbTdEtbAMrmvPInOaoK3vY9606 - false biotin tag:?-? sufficient binding region:1-209|fc-igg1:c-c|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:P52793 intact:EBI-2566560 intact:EBI-5241529|uniprotkb:P97331|ensembl:ENSMUSP00000029566 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:efna1_mouse(display_long)|uniprotkb:Efna1(gene name)|psi-mi:Efna1(display_short)|uniprotkb:Epgl1(gene name synonym)|uniprotkb:Epl1(gene name synonym)|uniprotkb:Lerk1(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 1(gene name synonym)|uniprotkb:Immediate early response protein B61(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432753|imex:IM-26494-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_034237.3|ensembl:ENSMUSG00000027954(gene)|ensembl:ENSMUST00000029566(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003199"(endocardial cushion to mesenchymal transition involved in heart valve formation)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014028"(notochord formation)|go:"GO:0016477"(cell migration)|go:"GO:0030182"(neuron differentiation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043535"(regulation of blood vessel endothelial cell migration)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034252|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665 - - - figure legend:Table 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:TMdL2OCslW4zUNIv7p+p0e/+9MM10090 - false biotin tag:?-? sufficient binding region:19-182|fc-igg1:c-c|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:P70211 intact:EBI-2566560 intact:EBI-1798863|uniprotkb:G3X9X6|ensembl:ENSMUSP00000110593 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:dcc_mouse(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432794|imex:IM-26494-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:XP_006525651.1|refseq:NP_031857.2|dip:DIP-46587N|ensembl:ENSMUSG00000060534(gene)|ensembl:ENSMUST00000114943(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021965"(spinal cord ventral commissure morphogenesis)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0033563"(dorsal/ventral axon guidance)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010560(Neogenin, C-terminal)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033012|interpro:IPR036116|interpro:IPR036179|mint:P70211|rcsb pdb:3PZD|rcsb pdb:4PLO|reactome:R-MMU-373752|reactome:R-MMU-418885|reactome:R-MMU-418889 - - - figure legend:Table 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:EMyR8LhWLCvJIBIAEn9dULe8Xfo10090 - false biotin tag:?-? sufficient binding region:1-1097|fc-igg1:c-c|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:O15041 intact:EBI-2566560 intact:EBI-7283693|uniprotkb:Q75M97|uniprotkb:B4E1P1|uniprotkb:Q75M94|intact:MINT-4507944|ensembl:ENSP00000496491 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:sem3e_human(display_long)|uniprotkb:SEMA3E(gene name)|psi-mi:SEMA3E(display_short)|uniprotkb:KIAA0331(gene name synonym)|uniprotkb:SEMAH(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432832|imex:IM-26494-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_036563.1|refseq:NP_001171600.1|ensembl:ENSG00000170381(gene)|ensembl:ENST00000643230(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050808"(synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015513(Semaphorin 3E)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|mint:O15041|reactome:R-HSA-416700 - - comment:mint figure legend:Table 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:m6pJKIlr+wF5rd6krKT5Q1MnE6s9606 - false biotin tag:?-? sufficient binding region:25-775|his tag:n-n|mutation:557-557,560-560 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q9HCK4 intact:EBI-2566560 intact:EBI-399800|ensembl:ENSP00000417164|uniprotkb:O43608|uniprotkb:Q19AB4|uniprotkb:Q19AB5|intact:EBI-28972899 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:robo2_human(display_long)|uniprotkb:ROBO2(gene name)|psi-mi:ROBO2(display_short)|uniprotkb:KIAA1568(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432851|imex:IM-26494-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) ensembl:ENSG00000185008(gene)|ensembl:ENST00000461745(transcript)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021510"(spinal cord development)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0030673"(axolemma)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1UEM|rcsb pdb:1UJT|rcsb pdb:2EDJ|rcsb pdb:5NOI|rcsb pdb:6I9S|rcsb pdb:6IAA|reactome:R-HSA-376176|reactome:R-HSA-428542|reactome:R-HSA-8985801|reactome:R-HSA-9010553|reactome:R-HSA-9010642|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008046"(axon guidance receptor activity)|refseq:NP_002933.1|ensembl:ENSP00000417164|ensembl:ENST00000487694|ensembl:ENSP00000417335|refseq:NP_001122401.1|refseq:NP_001276968.1|refseq:NP_001276969.1|refseq:NP_001276994.1 - - - figure legend:Table 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:AYfQ3Fza8Oo8wQ7Mzhqxm2kW3rs9606 - false biotin tag:?-? fc-igg1:c-c|sufficient binding region:1-312 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:P29323 intact:EBI-2566560 intact:EBI-1059294|uniprotkb:O43477|uniprotkb:Q5T0U6|uniprotkb:Q5T0U7|uniprotkb:Q5T0U8|intact:EBI-1383621|ensembl:ENSP00000383053 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:ephb2_human(display_long)|uniprotkb:EPHB2(gene name)|psi-mi:EPHB2(display_short)|uniprotkb:DRT(gene name synonym)|uniprotkb:EPHT3(gene name synonym)|uniprotkb:EPTH3(gene name synonym)|uniprotkb:ERK(gene name synonym)|uniprotkb:HEK5(gene name synonym)|uniprotkb:TYRO5(gene name synonym)|uniprotkb:EPH-like kinase 5(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-47(gene name synonym)|uniprotkb:Tyrosine-protein kinase TYRO5(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH-3(gene name synonym)|uniprotkb:Developmentally-regulated Eph-related tyrosine kinase(gene name synonym)|uniprotkb:ELK-related tyrosine kinase(gene name synonym)|uniprotkb:EPH tyrosine kinase 3(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432885|imex:IM-26494-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) refseq:NP_004433.2|refseq:NP_059145.2|refseq:NP_001296122.1|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016310"(phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904782"(negative regulation of NMDA glutamate receptor activity)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034238|interpro:IPR036116|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|mint:P29323|rcsb pdb:1B4F|rcsb pdb:1F0M|rcsb pdb:3ZFM|reactome:R-HSA-2682334|reactome:R-HSA-373760|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|rcsb pdb:2QBX|ensembl:ENSG00000133216(gene)|ensembl:ENST00000400191(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001655"(urogenital system development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042113"(B cell activation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050878"(regulation of body fluid levels)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|go:"GO:0106028"(neuron projection retraction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|dip:DIP-1162N - - - figure legend:Table 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:be++0VNRygM3NsDcVt/OQ6fHpr09606 - false biotin tag:?-? sufficient binding region:1-543|fc-igg1:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:16336" uniprotkb:Q8IUC0 intact:EBI-2566617 intact:EBI-11735920|uniprotkb:Q14D20|uniprotkb:Q3LI79|ensembl:ENSP00000347635 psi-mi:hyaluronan(display_short)|psi-mi:"CHEBI:16336"(display_long) psi-mi:kr131_human(display_long)|uniprotkb:KRTAP13-1(gene name)|psi-mi:KRTAP13-1(display_short)|uniprotkb:KAP13.1(gene name synonym)|uniprotkb:KRTAP13.1(gene name synonym)|uniprotkb:High sulfur keratin-associated protein 13.1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432925|imex:IM-26494-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_9(source reference) refseq:NP_853630.2|ensembl:ENSG00000198390(gene)|ensembl:ENST00000355459(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|interpro:IPR007951(PMG)|reactome:R-HSA-6805567 - - - figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:fOucuUNuXgKm5HWBY5kuka8kvDI9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:16336" uniprotkb:P35568 intact:EBI-2566617 intact:EBI-517592|intact:EBI-28983786|ensembl:ENSP00000304895 psi-mi:hyaluronan(display_short)|psi-mi:"CHEBI:16336"(display_long) psi-mi:irs1_human(display_long)|uniprotkb:IRS1(gene name)|psi-mi:IRS1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432933|imex:IM-26494-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_9(source reference) refseq:NP_005535.1|ensembl:ENSP00000304895|dip:DIP-523N|ensembl:ENSG00000169047(gene)|ensembl:ENST00000305123(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005901"(caveola)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:P35568|rcsb pdb:1IRS|rcsb pdb:1K3A|rcsb pdb:1QQG|rcsb pdb:2Z8C|rcsb pdb:5U1M|rcsb pdb:6BNT|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-112412|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-2219530|reactome:R-HSA-2428928|reactome:R-HSA-2586552|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-9603381|reactome:R-HSA-982772 - - - figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:n/9Epczwu5jOLSKCKhmIgR7CdOw9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:16336" uniprotkb:P14136-1 intact:EBI-2566617 intact:EBI-25432946|ensembl:ENSP00000466598 psi-mi:hyaluronan(display_short)|psi-mi:"CHEBI:16336"(display_long) psi-mi:p14136-1(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short)|uniprotkb:GFAP alpha(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432941|imex:IM-26494-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_9(source reference) ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|intact:EBI-744302(isoform-parent) - - - figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:16336" uniprotkb:Q16836 intact:EBI-2566617 intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4 psi-mi:hyaluronan(display_short)|psi-mi:"CHEBI:16336"(display_long) psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432956|imex:IM-26494-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_9(source reference) interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3 - - - figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:16336" uniprotkb:O00214-2 intact:EBI-2566617 intact:EBI-12069522|ensembl:ENSP00000309576|ensembl:ENSP00000431398|ensembl:ENSP00000435460|ensembl:ENSP00000408657 psi-mi:hyaluronan(display_short)|psi-mi:"CHEBI:16336"(display_long) psi-mi:o00214-2(display_long)|uniprotkb:LGALS8(gene name)|psi-mi:LGALS8(display_short)|uniprotkb:Po66 carbohydrate-binding protein(gene name synonym)|uniprotkb:Prostate carcinoma tumor antigen 1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-25432964|imex:IM-26494-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_9(source reference) ensembl:ENSG00000116977(gene)|ensembl:ENST00000352231(transcript)|ensembl:ENST00000450372(transcript)|ensembl:ENST00000526589(transcript)|ensembl:ENST00000527974(transcript)|intact:EBI-740058(isoform-parent)|uniprotkb:O00214-2(isoform-parent) - - isoform-comment:"Ref.8 (AAL77076) sequence is in conflict in position: 220:M->T." figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/02/21 - rogid:7X26MEsPRfXZ3GkTd2j34cmfRzo9606 - false biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9UHD2 intact:EBI-20725289 intact:EBI-356402|intact:EBI-5773956|intact:EBI-1383470|uniprotkb:Q8IYV3|uniprotkb:Q9NUJ5|ensembl:ENSP00000329967|ensembl:ENSP00000498995|uniprotkb:A8K4S4 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:tbk1_human(display_long)|uniprotkb:TBK1(gene name)|psi-mi:TBK1(display_short)|uniprotkb:NAK(gene name synonym)|uniprotkb:TANK-binding kinase 1(gene name synonym)|uniprotkb:T2K(gene name synonym)|uniprotkb:NF-kappa-B-activating kinase(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563523|imex:IM-26494-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_037386.1|go:"GO:0004672"(protein kinase activity)|ensembl:ENSG00000183735(gene)|ensembl:ENST00000331710(transcript)|ensembl:ENST00000650790(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044565"(dendritic cell proliferation)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901214"(regulation of neuron death)|go:"GO:1904417"(positive regulation of xenophagy)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR041087|interpro:IPR041309|mint:Q9UHD2|rcsb pdb:4EFO|rcsb pdb:4EUT|rcsb pdb:4EUU|rcsb pdb:4IM0|rcsb pdb:4IM2|rcsb pdb:4IM3|rcsb pdb:4IW0|rcsb pdb:4IWO|rcsb pdb:4IWP|rcsb pdb:4IWQ|rcsb pdb:5EOA|rcsb pdb:5EOF|rcsb pdb:5EP6|rcsb pdb:5W5V|rcsb pdb:6BNY|rcsb pdb:6BOD|rcsb pdb:6BOE|rcsb pdb:6CQ0|rcsb pdb:6CQ4|rcsb pdb:6CQ5|rcsb pdb:6NT9|rcsb pdb:6O8B|rcsb pdb:6RSR|rcsb pdb:6RST|rcsb pdb:6RSU|reactome:R-HSA-1606341|reactome:R-HSA-168928|reactome:R-HSA-3134975|reactome:R-HSA-3249367|reactome:R-HSA-3270619|reactome:R-HSA-9008059|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-9679191|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0009615"(response to virus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|refseq:XP_005268866.1|refseq:XP_005268867.1|dip:DIP-27529N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:Cf+RbPJBZTpm7XIqbAD2OEC6VEs9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9UBS0-1 intact:EBI-20725289 intact:EBI-26563533|ensembl:ENSP00000308413 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9ubs0-1(display_long)|uniprotkb:70 kDa ribosomal protein S6 kinase 2(gene name synonym)|uniprotkb:S6 kinase-related kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 14B(gene name synonym)|uniprotkb:p70 ribosomal S6 kinase beta(gene name synonym)|uniprotkb:RPS6KB2(gene name)|psi-mi:RPS6KB2(display_short)|uniprotkb:STK14B(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563540|imex:IM-26494-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000175634(gene)|ensembl:ENST00000312629(transcript)|intact:EBI-3905921(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:5+kV2nr99KWLmrnfXt7Vr6L83xM9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P53350 intact:EBI-20725289 intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563550|imex:IM-26494-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:fBOK366hV6mDprx9IWhz43gPcJE9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P30530-1 intact:EBI-20725289 intact:EBI-26563560|ensembl:ENSP00000301178 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p30530-1(display_long)|uniprotkb:AXL oncogene(gene name synonym)|uniprotkb:AXL(gene name)|psi-mi:AXL(display_short)|uniprotkb:UFO(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563567|imex:IM-26494-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000167601(gene)|ensembl:ENST00000301178(transcript)|intact:EBI-2850927(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:GMGuoyV5CkwYx9zsEx4NTCkPezA9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O60285-1 intact:EBI-20725289 intact:EBI-26563577|ensembl:ENSP00000261402 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o60285-1(display_long)|uniprotkb:AMPK-related protein kinase 5(gene name synonym)|uniprotkb:Omphalocele kinase 1(gene name synonym)|uniprotkb:NUAK1(gene name)|psi-mi:NUAK1(display_short)|uniprotkb:ARK5(gene name synonym)|uniprotkb:KIAA0537(gene name synonym)|uniprotkb:OMPHK1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563586|imex:IM-26494-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000074590(gene)|ensembl:ENST00000261402(transcript)|intact:EBI-1046789(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:6P4GR2fFthBsniiqq/yy3Sxm9Sg9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O15111 intact:EBI-20725289 intact:EBI-81249|uniprotkb:O14666|uniprotkb:Q13132|uniprotkb:Q5W0I4|uniprotkb:Q92467|ensembl:ENSP00000359424|intact:EBI-28970970 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ikka_human(display_long)|uniprotkb:CHUK(gene name)|psi-mi:CHUK(display_short)|uniprotkb:IKKA(gene name synonym)|uniprotkb:TCF16(gene name synonym)|uniprotkb:I-kappa-B kinase 1(gene name synonym)|uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)|uniprotkb:Transcription factor 16(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563596|imex:IM-26494-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001269.3|ensembl:ENSP00000359424|ensembl:ENSG00000213341(gene)|ensembl:ENST00000370397(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0010034"(response to acetate)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022007|interpro:IPR041185|mint:O15111|rcsb pdb:3BRT|rcsb pdb:5EBZ|rcsb pdb:5TQW|rcsb pdb:5TQX|rcsb pdb:5TQY|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-198323|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5674400|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|dip:DIP-27526N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:FVB/gXjSBTB9hdq9pycQogxesms9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P06493-1 intact:EBI-20725289 intact:EBI-11614201|ensembl:ENSP00000378699 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p06493-1(display_long)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:p34 protein kinase(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563606|imex:IM-26494-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|intact:EBI-444308(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9H1R3 intact:EBI-20725289 intact:EBI-356910|uniprotkb:Q569L1|uniprotkb:Q96I84|ensembl:ENSP00000365152|ensembl:ENSP00000365162 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:mylk2_human(display_long)|uniprotkb:MYLK2(gene name)|psi-mi:MYLK2(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563616|imex:IM-26494-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_149109.1|ensembl:ENSP00000365152|ensembl:ENSP00000365162|ensembl:ENSG00000101306(gene)|ensembl:ENST00000375985(transcript)|ensembl:ENST00000375994(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004687"(myosin light chain kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014816"(skeletal muscle satellite cell differentiation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030017"(sarcomere)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032971"(regulation of muscle filament sliding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042717|rcsb pdb:2LV6|rcsb pdb:3KF9 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:VfJn/QlOkBjTcPHsi+5EkEQY3/c9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O60563-1 intact:EBI-20725289 intact:EBI-26563626|ensembl:ENSP00000261900 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o60563-1(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563632|imex:IM-26494-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|intact:EBI-2479671(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P10721-1 intact:EBI-20725289 intact:EBI-26563642|ensembl:ENSP00000288135 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p10721-1(display_long)|uniprotkb:Piebald trait protein(gene name synonym)|uniprotkb:Proto-oncogene c-Kit(gene name synonym)|uniprotkb:Tyrosine-protein kinase Kit(gene name synonym)|uniprotkb:p145 c-kit(gene name synonym)|uniprotkb:v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog(gene name synonym)|uniprotkb:"GNNK(+)"(isoform synonym)|uniprotkb:"KitA(+)"(isoform synonym)|uniprotkb:KIT(gene name)|psi-mi:KIT(display_short)|uniprotkb:SCFR(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563651|imex:IM-26494-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1379503(isoform-parent)|ensembl:ENSG00000157404(gene)|ensembl:ENST00000288135(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:FZGJcek6hOsn4AKqu7bBMmfuGKU9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q15418-1 intact:EBI-20725289 intact:EBI-26563661|ensembl:ENSP00000363283|ensembl:ENSP00000486881 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q15418-1(display_long)|uniprotkb:90 kDa ribosomal protein S6 kinase 1(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1a(gene name synonym)|uniprotkb:Ribosomal S6 kinase 1(gene name synonym)|uniprotkb:RPS6KA1(gene name)|psi-mi:RPS6KA1(display_short)|uniprotkb:MAPKAPK1A(gene name synonym)|uniprotkb:RSK1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563669|imex:IM-26494-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000117676(gene)|ensembl:ENSG00000281877(gene)|ensembl:ENST00000374168(transcript)|ensembl:ENST00000629832(transcript)|intact:EBI-963034(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:kx+9PwIH4KR0iTxpv6epDKNqHBE9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q06187-1 intact:EBI-20725289 intact:EBI-26563679|ensembl:ENSP00000308176 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q06187-1(display_long)|uniprotkb:Agammaglobulinemia tyrosine kinase(gene name synonym)|uniprotkb:B-cell progenitor kinase(gene name synonym)|uniprotkb:Bruton tyrosine kinase(gene name synonym)|uniprotkb:BTK(gene name)|psi-mi:BTK(display_short)|uniprotkb:AGMX1(gene name synonym)|uniprotkb:ATK(gene name synonym)|uniprotkb:BPK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563688|imex:IM-26494-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000010671(gene)|ensembl:ENST00000308731(transcript)|intact:EBI-624835(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:Zqb1CQYac99t12LVwMCVK56IJQQ9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q15349-1 intact:EBI-20725289 intact:EBI-26563705|ensembl:ENSP00000265678 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q15349-1(display_long)|uniprotkb:90 kDa ribosomal protein S6 kinase 2(gene name synonym)|uniprotkb:MAP kinase-activated protein kinase 1c(gene name synonym)|uniprotkb:Ribosomal S6 kinase 3(gene name synonym)|uniprotkb:pp90RSK3(gene name synonym)|uniprotkb:RPS6KA2(gene name)|psi-mi:RPS6KA2(display_short)|uniprotkb:MAPKAPK1C(gene name synonym)|uniprotkb:RSK3(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563698|imex:IM-26494-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1384149(isoform-parent)|ensembl:ENSG00000071242(gene)|ensembl:ENST00000265678(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:990LeSQ83sti7xG5qGEoFLDkubs9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O00506-1 intact:EBI-20725289 intact:EBI-26563718|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o00506-1(display_long)|uniprotkb:Ste20-like kinase(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563726|imex:IM-26494-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|intact:EBI-618295(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q16288-3 intact:EBI-20725289 intact:EBI-26563736|ensembl:ENSP00000377990 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q16288-3(display_long)|uniprotkb:GP145-TrkC(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 3(gene name synonym)|uniprotkb:TrkC tyrosine kinase(gene name synonym)|uniprotkb:C(isoform synonym)|uniprotkb:NTRK3(gene name)|psi-mi:NTRK3(display_short)|uniprotkb:TRKC(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563744|imex:IM-26494-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000140538(gene)|ensembl:ENST00000394480(transcript)|intact:EBI-3936704(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:cUiMWnb8bg+AgxbX4bmtAEW2qNU9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P51813 intact:EBI-20725289 intact:EBI-696657|uniprotkb:A6NIH9|uniprotkb:O60564|uniprotkb:Q12871|ensembl:ENSP00000308774|ensembl:ENSP00000340082|ensembl:ENSP00000350224 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:bmx_human(display_long)|uniprotkb:Bone marrow tyrosine kinase gene in chromosome X protein(gene name synonym)|uniprotkb:Epithelial and endothelial tyrosine kinase(gene name synonym)|uniprotkb:NTK38(gene name synonym)|uniprotkb:BMX(gene name)|psi-mi:BMX(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563754|imex:IM-26494-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001712.1|refseq:NP_975010.1|refseq:NP_001307795.1|ensembl:ENSG00000102010(gene)|ensembl:ENST00000342014(transcript)|ensembl:ENST00000348343(transcript)|ensembl:ENST00000357607(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007498"(mesoderm development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028840|interpro:IPR035875|interpro:IPR036860|rcsb pdb:2EKX|rcsb pdb:2YS2|rcsb pdb:3SXR|rcsb pdb:3SXS|rcsb pdb:6I99|reactome:R-HSA-111465|reactome:R-HSA-1660499 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:vEWqPrMe5xCQRPeNReXM+8Djcjg9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P51955-1 intact:EBI-20725289 intact:EBI-687792|ensembl:ENSP00000355966 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p51955-1(display_long)|uniprotkb:Nek2A(isoform synonym)|uniprotkb:NEK2(gene name)|psi-mi:NEK2(display_short)|uniprotkb:NEK2A(gene name synonym)|uniprotkb:NLK1(gene name synonym)|uniprotkb:HSPK 21(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 2(gene name synonym)|uniprotkb:NimA-like protein kinase 1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563764|imex:IM-26494-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-633182(nek2_human)|ensembl:ENSG00000117650(gene)|ensembl:ENST00000366999(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:7iozc82+IF+sGyerzvp571Uc1RM9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P51956-1 intact:EBI-20725289 intact:EBI-26563774|ensembl:ENSP00000480328|ensembl:ENSP00000484443 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p51956-1(display_long)|uniprotkb:HSPK 36(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 3(gene name synonym)|uniprotkb:NEK3(gene name)|psi-mi:NEK3(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563780|imex:IM-26494-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000136098(gene)|ensembl:ENST00000610828(transcript)|ensembl:ENST00000618534(transcript)|intact:EBI-476041(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:fS8rra+/rmzij9G9WWtK6b8Pf+E9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9UIK4-1 intact:EBI-20725289 intact:EBI-26563790|ensembl:ENSP00000261891|ensembl:ENSP00000408277 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9uik4-1(display_long)|uniprotkb:DAP-kinase-related protein 1(gene name synonym)|uniprotkb:Alpha(isoform synonym)|uniprotkb:DAPK2(gene name)|psi-mi:DAPK2(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563797|imex:IM-26494-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000035664(gene)|ensembl:ENST00000261891(transcript)|ensembl:ENST00000457488(transcript)|intact:EBI-77154(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:BfVpnvUBAjf3E3djVaqnEqbGP8Q9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P36507 intact:EBI-20725289 intact:EBI-1056930|ensembl:ENSP00000262948|intact:EBI-15586042 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:mp2k2_human(display_long)|uniprotkb:MAP2K2(gene name)|psi-mi:MAP2K2(display_short)|uniprotkb:MEK2(gene name synonym)|uniprotkb:MKK2(gene name synonym)|uniprotkb:PRKMK2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563807|imex:IM-26494-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_109587.1|ensembl:ENSG00000126934(gene)|ensembl:ENST00000262948(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P36507|rcsb pdb:1S9I|rcsb pdb:4H3Q|reactome:R-HSA-112411|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|go:"GO:0005634"(nucleus)|dip:DIP-29119N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:JnGMm7dA0eZgBV4A/n+ZjE8ATq49606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P42684-1 intact:EBI-20725289 intact:EBI-15691099|ensembl:ENSP00000427562 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p42684-1(display_long)|uniprotkb:Abelson tyrosine-protein kinase 2(gene name synonym)|uniprotkb:ABL2(gene name)|psi-mi:ABL2(display_short)|uniprotkb:ABLL(gene name synonym)|uniprotkb:ARG(gene name synonym)|uniprotkb:Abelson murine leukemia viral oncogene homolog 2(gene name synonym)|uniprotkb:Abelson-related gene protein(gene name synonym)|uniprotkb:Tyrosine-protein kinase ARG(gene name synonym)|uniprotkb:1BLCTL(isoform synonym)|uniprotkb:IB(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563817|imex:IM-26494-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1102694(isoform-parent)|ensembl:ENSG00000143322(gene)|ensembl:ENST00000502732(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:ct5SG4m0wewDSllBklIOi48BV7Q9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O75676-1 intact:EBI-20725289 intact:EBI-26563847|ensembl:ENSP00000333896 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o75676-1(display_long)|uniprotkb:90 kDa ribosomal protein S6 kinase 4(gene name synonym)|uniprotkb:Nuclear mitogen- and stress-activated protein kinase 2(gene name synonym)|uniprotkb:Ribosomal protein kinase B(gene name synonym)|uniprotkb:RPS6KA4(gene name)|psi-mi:RPS6KA4(display_short)|uniprotkb:MSK2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563854|imex:IM-26494-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-73933(isoform-parent)|ensembl:ENSG00000162302(gene)|ensembl:ENST00000334205(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:C2Zpzuq3c99BNpYuJBozPWc/1DA9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96GD4-1 intact:EBI-20725289 intact:EBI-26563864|ensembl:ENSP00000463999 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q96gd4-1(display_long)|uniprotkb:Aurora 1(gene name synonym)|uniprotkb:Aurora- and IPL1-like midbody-associated protein 1(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 2(gene name synonym)|uniprotkb:STK-1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 12(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 5(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-B(gene name synonym)|uniprotkb:AURKB(gene name)|psi-mi:AURKB(display_short)|uniprotkb:AIK2(gene name synonym)|uniprotkb:AIM1(gene name synonym)|uniprotkb:AIRK2(gene name synonym)|uniprotkb:ARK2(gene name synonym)|uniprotkb:STK1(gene name synonym)|uniprotkb:STK12(gene name synonym)|uniprotkb:STK5(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563877|imex:IM-26494-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000178999(gene)|ensembl:ENST00000585124(transcript)|intact:EBI-624291(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:4pmZhSoAp5JmH19k2tT+w3z9Hgo9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9Y6E0-1 intact:EBI-20725289 intact:EBI-26563887|ensembl:ENSP00000365730 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9y6e0-1(display_long)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563895|imex:IM-26494-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|intact:EBI-740175(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P78368 intact:EBI-20725289 intact:EBI-748380|uniprotkb:O00704|uniprotkb:Q8WUB1|uniprotkb:B5BU42|ensembl:ENSP00000255641 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:kc1g2_human(display_long)|uniprotkb:CK1G2(gene name synonym)|uniprotkb:CSNK1G2(gene name)|psi-mi:CSNK1G2(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563905|imex:IM-26494-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001310.3|ensembl:ENSG00000133275(gene)|ensembl:ENST00000255641(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022247|rcsb pdb:2C47|reactome:R-HSA-1660661|reactome:R-HSA-4641262 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:h+GOdcwwLTmwj0dQKT1JQGwoaC09606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O43293-1 intact:EBI-20725289 intact:EBI-9691444|ensembl:ENSP00000301264|ensembl:ENSP00000442973 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o43293-1(display_long)|uniprotkb:ZIPK-L(isoform synonym)|uniprotkb:DAPK3(gene name)|psi-mi:DAPK3(display_short)|uniprotkb:ZIPK(gene name synonym)|uniprotkb:DAP-like kinase(gene name synonym)|uniprotkb:MYPT1 kinase(gene name synonym)|uniprotkb:Zipper-interacting protein kinase(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26563915|imex:IM-26494-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-77293(isoform-parent)|ensembl:ENSG00000167657(gene)|ensembl:ENST00000301264(transcript)|ensembl:ENST00000545797(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2020/12/11 - rogid:s8wsdvHltjaM7k0sJRNSjpXVpwM9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q13237-1 intact:EBI-20725289 intact:EBI-26584561|ensembl:ENSP00000264399|ensembl:ENSP00000378945 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q13237-1(display_long)|uniprotkb:cGMP-dependent protein kinase II(gene name synonym)|uniprotkb:PRKG2(gene name)|psi-mi:PRKG2(display_short)|uniprotkb:PRKGR2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584568|imex:IM-26494-150 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000138669(gene)|ensembl:ENST00000264399(transcript)|ensembl:ENST00000395578(transcript)|intact:EBI-6380084(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:1pS6khR8w8DkGtVHNUngvsZmW2k9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P51957-1 intact:EBI-20725289 intact:EBI-20829359|ensembl:ENSP00000233027 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p51957-1(display_long)|uniprotkb:Never in mitosis A-related kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NRK2(gene name synonym)|uniprotkb:NEK4(gene name)|psi-mi:NEK4(display_short)|uniprotkb:STK2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584578|imex:IM-26494-130 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000114904(gene)|ensembl:ENST00000233027(transcript)|intact:EBI-8798332(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:365hov+IcvvftTCyDltKgrlhdjM9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P33981-1 intact:EBI-20725289 intact:EBI-15986834|ensembl:ENSP00000358813 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p33981-1(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584588|imex:IM-26494-152 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1645856(isoform-parent)|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P49674 intact:EBI-20725289 intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584599|imex:IM-26494-132 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:evdzz03ba4MFWavN9xRae/Wxwio9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P52564-1 intact:EBI-20725289 intact:EBI-15750978|ensembl:ENSP00000468348 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p52564-1(display_long)|uniprotkb:MAP2K6(gene name)|psi-mi:MAP2K6(display_short)|uniprotkb:MEK6(gene name synonym)|uniprotkb:MKK6(gene name synonym)|uniprotkb:PRKMK6(gene name synonym)|uniprotkb:SKK3(gene name synonym)|uniprotkb:MAPK/ERK kinase 6(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 3(gene name synonym)|uniprotkb:MKK6b(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584612|imex:IM-26494-154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-448135(isoform-parent)|ensembl:ENSG00000108984(gene)|ensembl:ENST00000590474(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:7RQ/LBAms1wKpD6Rv+ijvMIzDXA9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q13153-1 intact:EBI-20725289 intact:EBI-15628682|ensembl:ENSP00000348696 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q13153-1(display_long)|uniprotkb:PAK1(gene name)|psi-mi:PAK1(display_short)|uniprotkb:Alpha-PAK(gene name synonym)|uniprotkb:p21-activated kinase 1(gene name synonym)|uniprotkb:p65-PAK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584622|imex:IM-26494-134 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1307(isoform-parent)|uniprotkb:Q13153-1(isoform-parent)|ensembl:ENSG00000149269(gene)|ensembl:ENST00000356341(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:SbPL5+9oNR0PaVRo6xfpbAMQKB49606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8N568 intact:EBI-20725289 intact:EBI-2930406|ensembl:ENSP00000296550|uniprotkb:Q59GC8|uniprotkb:Q8N399|uniprotkb:C9J5Q9 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:dclk2_human(display_long)|uniprotkb:DCLK2(gene name)|psi-mi:DCLK2(display_short)|uniprotkb:DCAMKL2(gene name synonym)|uniprotkb:DCDC3B(gene name synonym)|uniprotkb:DCK2(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 2(gene name synonym)|uniprotkb:Doublecortin-like kinase 2(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3B(gene name synonym)|uniprotkb:CaMK-like CREB regulatory kinase 2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584632|imex:IM-26494-136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036572|go:"GO:0106311"|ensembl:ENSG00000170390(gene)|ensembl:ENST00000296550(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008017"(microtubule binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|refseq:NP_001035350.2|refseq:NP_001035351.4|refseq:XP_005262843.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:yEXKVJ2aLrGokghQA1Wvlb7LNpo9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P29317-1 intact:EBI-20725289 intact:EBI-26584642|ensembl:ENSP00000351209 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p29317-1(display_long)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:EPHA2(gene name)|psi-mi:EPHA2(display_short)|uniprotkb:ECK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584649|imex:IM-26494-156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-702104(isoform-parent)|ensembl:ENSG00000142627(gene)|ensembl:ENST00000358432(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:9VFikLd4ftRmEyBpY0JHdpHINT09606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q16620-4 intact:EBI-20725289 intact:EBI-26584659|ensembl:ENSP00000277120 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q16620-4(display_long)|uniprotkb:GP145-TrkB(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 2(gene name synonym)|uniprotkb:TrkB tyrosine kinase(gene name synonym)|uniprotkb:Tropomyosin-related kinase B(gene name synonym)|uniprotkb:NTRK2(gene name)|psi-mi:NTRK2(display_short)|uniprotkb:TRKB(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584666|imex:IM-26494-158 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000148053(gene)|ensembl:ENST00000277120(transcript)|intact:EBI-3904881(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:yRirSsiv9VU5xLVWpvIaNTA++oA9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P07947 intact:EBI-20725289 intact:EBI-515331|uniprotkb:A6NLB3|uniprotkb:D3DUH1|intact:EBI-28995389|ensembl:ENSP00000324740|ensembl:ENSP00000462468 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:yes_human(display_long)|uniprotkb:p61-Yes(gene name synonym)|uniprotkb:Proto-oncogene c-Yes(gene name synonym)|uniprotkb:YES1(gene name)|psi-mi:YES1(display_short)|uniprotkb:YES(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584676|imex:IM-26494-138 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_016881449.1|refseq:NP_005424.1|ensembl:ENSP00000324740|ensembl:ENSP00000462468|dip:DIP-33849N|ensembl:ENSG00000176105(gene)|ensembl:ENST00000314574(transcript)|ensembl:ENST00000584307(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050900"(leukocyte migration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035751|interpro:IPR036028|interpro:IPR036860|mint:P07947|rcsb pdb:2HDA|reactome:R-HSA-1227986|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2682334|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-8940973|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:Wo+NWxPVSmF8W6ZHQmTPpg3YuY09606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96PF2 intact:EBI-20725289 intact:EBI-852089|uniprotkb:Q8IY55|ensembl:ENSP00000382544 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:tssk2_human(display_long)|uniprotkb:Serine/threonine-protein kinase 22B(gene name synonym)|uniprotkb:DiGeorge syndrome protein G(gene name synonym)|uniprotkb:TSSK2(gene name)|psi-mi:TSSK2(display_short)|uniprotkb:DGSG(gene name synonym)|uniprotkb:SPOGA2(gene name synonym)|uniprotkb:STK22B(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584731|imex:IM-26494-160 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_443732.3|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007286"(spermatid development)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0005524"(ATP binding)|ensembl:ENSG00000206203(gene)|ensembl:ENST00000399635(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:Uz36gAlTmZRfyxDOURZUMXC16fs9606 - false tag:?-?|biotin tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96SB4-2 intact:EBI-20725289 intact:EBI-5773439|intact:EBI-7160066|intact:EBI-7160351|intact:EBI-7160024|intact:MINT-262733|ensembl:ENSP00000362931 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q96sb4-2(display_long)|uniprotkb:SFRS protein kinase 1(gene name synonym)|uniprotkb:Serine/arginine-rich protein-specific kinase 1(gene name synonym)|uniprotkb:SRPK1(gene name)|psi-mi:SRPK1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584764|imex:IM-26494-140 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-539478(isoform-parent)|ensembl:ENSG00000096063(gene)|ensembl:ENST00000373825(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:e335v+Im7IjFP1CdFzPefvU8iQo9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9Y6M4-1 intact:EBI-20725289 intact:EBI-26584696|ensembl:ENSP00000354942 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9y6m4-1(display_long)|uniprotkb:CSNK1G3(gene name)|psi-mi:CSNK1G3(display_short)|uniprotkb:3(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584774|imex:IM-26494-162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1383789(isoform-parent)|ensembl:ENSG00000151292(gene)|ensembl:ENST00000361991(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:+K51OlNSap5NlCBoS+RRHE0MDTQ9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P04629-1 intact:EBI-20725289 intact:EBI-26584710|ensembl:ENSP00000431418 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p04629-1(display_long)|uniprotkb:Tropomyosin-related kinase A(gene name synonym)|uniprotkb:Tyrosine kinase receptor(gene name synonym)|uniprotkb:Tyrosine kinase receptor A(gene name synonym)|uniprotkb:gp140trk(gene name synonym)|uniprotkb:p140-TrkA(gene name synonym)|uniprotkb:TrkAII(isoform synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 1(gene name synonym)|uniprotkb:TRK1-transforming tyrosine kinase protein(gene name synonym)|uniprotkb:NTRK1(gene name)|psi-mi:NTRK1(display_short)|uniprotkb:MTC(gene name synonym)|uniprotkb:TRK(gene name synonym)|uniprotkb:TRKA(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584787|imex:IM-26494-164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000198400(gene)|ensembl:ENST00000524377(transcript)|intact:EBI-1028226(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:23wX9uYjIrxsAIcCHQ1IYMsICmw9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P07948-1 intact:EBI-20725289 intact:EBI-6895930|ensembl:ENSP00000428924 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p07948-1(display_long)|uniprotkb:LYN A(isoform synonym)|uniprotkb:p56lyn(isoform synonym)|uniprotkb:LYN(gene name)|psi-mi:LYN(display_short)|uniprotkb:JTK8(gene name synonym)|uniprotkb:Lck/Yes-related novel protein tyrosine kinase(gene name synonym)|uniprotkb:V-yes-1 Yamaguchi sarcoma viral related oncogene homolog(gene name synonym)|uniprotkb:p53Lyn(gene name synonym)|uniprotkb:p56Lyn(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584799|imex:IM-26494-142 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000254087(gene)|ensembl:ENST00000519728(transcript)|intact:EBI-79452(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:SqXPSC+g2ZuGHy6TAPV4HcpXe6U9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P07332-1 intact:EBI-20725289 intact:EBI-26584809|ensembl:ENSP00000331504 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p07332-1(display_long)|uniprotkb:Feline sarcoma/Fujinami avian sarcoma oncogene homolog(gene name synonym)|uniprotkb:Proto-oncogene c-Fes(gene name synonym)|uniprotkb:Proto-oncogene c-Fps(gene name synonym)|uniprotkb:p93c-fes(gene name synonym)|uniprotkb:FES(gene name)|psi-mi:FES(display_short)|uniprotkb:FPS(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584816|imex:IM-26494-144 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000182511(gene)|ensembl:ENST00000328850(transcript)|intact:EBI-1055635(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:jsI2Ytqu7whZlUt7qISAW3W3WqQ9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:18250" uniprotkb:Q9NWZ3-1 intact:EBI-2566560 intact:EBI-26584826|ensembl:ENSP00000446490|ensembl:ENSP00000479889 psi-mi:chondroitin_sulfate(display_short)|psi-mi:"CHEBI:18250"(display_long) psi-mi:q9nwz3-1(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-64(gene name synonym)|uniprotkb:IRAK4(gene name)|psi-mi:IRAK4(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584832|imex:IM-26494-166 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) matrixdb:GAG_4(source reference) ensembl:ENSG00000198001(gene)|ensembl:ENST00000551736(transcript)|ensembl:ENST00000613694(transcript)|intact:EBI-448378(isoform-parent) - - - figure legend:Table 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:/m8S9iEd9yAaaA7asytw8VKbd5s9606 - false biotin tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9NWZ3-1 intact:EBI-20725289 intact:EBI-26584826|ensembl:ENSP00000446490|ensembl:ENSP00000479889 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9nwz3-1(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-64(gene name synonym)|uniprotkb:IRAK4(gene name)|psi-mi:IRAK4(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584838|imex:IM-26494-146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000198001(gene)|ensembl:ENST00000551736(transcript)|ensembl:ENST00000613694(transcript)|intact:EBI-448378(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:/m8S9iEd9yAaaA7asytw8VKbd5s9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P29322-1 intact:EBI-20725289 intact:EBI-26584855|ensembl:ENSP00000166244 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p29322-1(display_long)|uniprotkb:EPH- and ELK-related kinase(gene name synonym)|uniprotkb:EPH-like kinase 3(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EEK(gene name synonym)|uniprotkb:EPHA8(gene name)|psi-mi:EPHA8(display_short)|uniprotkb:EEK(gene name synonym)|uniprotkb:HEK3(gene name synonym)|uniprotkb:KIAA1459(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26584848|imex:IM-26494-148 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000070886(gene)|ensembl:ENST00000166244(transcript)|intact:EBI-3905018(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/01/08 - rogid:T7sTgV46UYcGqs0KJIXmgVbePwI9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9BXA7 intact:EBI-20725289 intact:EBI-6423734|ensembl:ENSP00000375081|uniprotkb:B2R8D9 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:tssk1_human(display_long)|uniprotkb:TSSK1B(gene name)|psi-mi:TSSK1B(display_short)|uniprotkb:SPOGA1(gene name synonym)|uniprotkb:SPOGA4(gene name synonym)|uniprotkb:STK22A(gene name synonym)|uniprotkb:STK22D(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 22A(gene name synonym)|uniprotkb:TSSK1(gene name synonym)|uniprotkb:FKSG81(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664830|imex:IM-26494-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000212122(gene)|ensembl:ENST00000390666(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007286"(spermatid development)|go:"GO:0031514"(motile cilium)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_114417.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:CGlDWDWKxFkpw5g2Hxu8JfQn7kw9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O14965 intact:EBI-20725289 intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664840|imex:IM-26494-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96L34-2 intact:EBI-20725289 intact:EBI-21537016 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q96l342(display_long)|uniprotkb:MARK4(gene name)|psi-mi:MARK4(display_short)|uniprotkb:KIAA1860(gene name synonym)|uniprotkb:MARKL1(gene name synonym)|uniprotkb:MARKL1S(isoform synonym)|uniprotkb:MARK4S(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664850|imex:IM-26494-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - uniprotkb:Q96L34-2(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:WZcpDF4c903uunbhkRycdXqovDw9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96PY6 intact:EBI-20725289 intact:EBI-373615|uniprotkb:Q9Y594|ensembl:ENSP00000408020|uniprotkb:Q14CB7|uniprotkb:Q5H9T1|uniprotkb:Q6PIB8|uniprotkb:Q96SS2|uniprotkb:Q9H6P7|uniprotkb:Q05DG5|uniprotkb:G5E9Z3 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:nek1_human(display_long)|uniprotkb:NEK1(gene name)|psi-mi:NEK1(display_short)|uniprotkb:KIAA1901(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-55(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664863|imex:IM-26494-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001186326.1|refseq:NP_001186327.1|refseq:NP_001186328.1|refseq:NP_001186329.1|refseq:NP_036356.1|ensembl:ENSG00000137601(gene)|ensembl:ENST00000439128(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4APC|rcsb pdb:4B9D|refseq:XP_011530305.1|refseq:XP_011530306.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:/Zes5a/DuVLXGUozIBoCHv4qtm89606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9NYL2-2 intact:EBI-20725289 intact:EBI-10255081|ensembl:ENSP00000340257|ensembl:ENSP00000439414 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9nyl2-2(display_long)|uniprotkb:MAP3K20(gene name)|psi-mi:MAP3K20(display_short)|uniprotkb:Human cervical cancer suppressor gene 4 protein(gene name synonym)|uniprotkb:Leucine zipper- and sterile alpha motif-containing kinase(gene name synonym)|uniprotkb:MLK-like mitogen-activated protein triple kinase(gene name synonym)|uniprotkb:MLTK(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase MLT(gene name synonym)|uniprotkb:Mixed lineage kinase-related kinase(gene name synonym)|uniprotkb:Sterile alpha motif- and leucine zipper-containing kinase AZK(gene name synonym)|uniprotkb:ZAK(gene name synonym)|uniprotkb:HCCS4(orf name)|uniprotkb:Beta(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664873|imex:IM-26494-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-602273(isoform-parent)|uniprotkb:Q9NYL2-2(isoform-parent)|ensembl:ENSG00000091436(gene)|ensembl:ENST00000338983(transcript)|ensembl:ENST00000539448(transcript) - - isoform-comment:Contains a phosphoserine at position 429. Contains a phosphoserine at position 339. Contains a phosphoserine at position 434. Contains a phosphoserine at position 454. figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:df3NraPaEZFk5cyZF+clB1Qy8sw9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P11362 intact:EBI-20725289 intact:EBI-1028277|uniprotkb:P17049|uniprotkb:Q02063|uniprotkb:Q02065|uniprotkb:Q14306|uniprotkb:Q14307|uniprotkb:Q8N685|uniprotkb:C1KBH8|uniprotkb:Q9UDF0|uniprotkb:Q9UDF1|uniprotkb:Q9UDF2|uniprotkb:Q59H40|uniprotkb:Q5BJG2|uniprotkb:A8K6T9|uniprotkb:A8K8V5|uniprotkb:Q53H63|uniprotkb:Q9UD50|intact:EBI-1058611|ensembl:ENSP00000400162 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:fgfr1_human(display_long)|uniprotkb:FGFR1(gene name)|psi-mi:FGFR1(display_short)|uniprotkb:FGFBR(gene name synonym)|uniprotkb:FLG(gene name synonym)|uniprotkb:FLT2(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 2(gene name synonym)|uniprotkb:Proto-oncogene c-Fgr(gene name synonym)|uniprotkb:BFGFR(gene name synonym)|uniprotkb:CEK(gene name synonym)|uniprotkb:HBGFR(gene name synonym)|uniprotkb:Basic fibroblast growth factor receptor 1(gene name synonym)|uniprotkb:N-sam(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664884|imex:IM-26494-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001167534.1|refseq:NP_001167535.1|refseq:NP_001167536.1|refseq:NP_001167537.1|refseq:NP_001167538.1|refseq:NP_056934.2|refseq:NP_075593.1|refseq:NP_075594.1|refseq:NP_075598.2|ensembl:ENSG00000077782(gene)|ensembl:ENST00000447712(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001501"(skeletal system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000546"(positive regulation of endothelial cell chemotaxis to fibroblast growth factor)|go:"GO:2001239"(regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016248(Fibroblast growth factor receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028174|interpro:IPR036179|interpro:IPR041159|mint:P11362|rcsb pdb:1AGW|rcsb pdb:1CVS|rcsb pdb:1EVT|rcsb pdb:1FGI|rcsb pdb:1FGK|rcsb pdb:1FQ9|go:"GO:0045666"(positive regulation of neuron differentiation)|rcsb pdb:1XR0|rcsb pdb:2CR3|rcsb pdb:2FGI|rcsb pdb:3C4F|rcsb pdb:3DPK|rcsb pdb:3GQI|rcsb pdb:3GQL|rcsb pdb:3JS2|rcsb pdb:3KRJ|rcsb pdb:3KRL|rcsb pdb:3KXX|rcsb pdb:3KY2|rcsb pdb:3OJV|rcsb pdb:3RHX|rcsb pdb:3TT0|rcsb pdb:4F63|rcsb pdb:4F64|rcsb pdb:4F65|rcsb pdb:4NK9|rcsb pdb:4NKA|rcsb pdb:4NKS|rcsb pdb:4RWI|rcsb pdb:4RWJ|rcsb pdb:4RWK|rcsb pdb:4RWL|rcsb pdb:4UWC|rcsb pdb:4UWY|rcsb pdb:4V01|rcsb pdb:4V04|rcsb pdb:4V05|rcsb pdb:4WUN|rcsb pdb:4ZSA|rcsb pdb:5A46|rcsb pdb:5A4C|rcsb pdb:5AM6|rcsb pdb:5AM7|rcsb pdb:5B7V|rcsb pdb:5EW8|rcsb pdb:5FLF|rcsb pdb:5O49|rcsb pdb:5O4A|rcsb pdb:5UQ0|rcsb pdb:5UR1|rcsb pdb:5VND|rcsb pdb:5W21|rcsb pdb:5W59|rcsb pdb:5Z0S|rcsb pdb:5ZV2|rcsb pdb:6C18|rcsb pdb:6C19|rcsb pdb:6C1B|rcsb pdb:6C1C|rcsb pdb:6C1O|rcsb pdb:6ITJ|rcsb pdb:6MZQ|rcsb pdb:6MZW|rcsb pdb:6NVL|rcsb pdb:6P68|rcsb pdb:6P69|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-1839120|rcsb pdb:4UWB|reactome:R-HSA-1839122|reactome:R-HSA-190370|reactome:R-HSA-190373|reactome:R-HSA-190374|reactome:R-HSA-2219530|reactome:R-HSA-375165|reactome:R-HSA-445144|reactome:R-HSA-5654219|reactome:R-HSA-5654687|reactome:R-HSA-5654688|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853336|reactome:R-HSA-5654726|dip:DIP-4019N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:th/BEfNYh60oKK7G0HFX+O1pXh89606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P04626-1 intact:EBI-20725289 intact:EBI-26664896|ensembl:ENSP00000269571 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p04626-1(display_long)|uniprotkb:Metastatic lymph node gene 19 protein(gene name synonym)|uniprotkb:Proto-oncogene Neu(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)|uniprotkb:Tyrosine kinase-type cell surface receptor HER2(gene name synonym)|uniprotkb:p185erbB2(gene name synonym)|uniprotkb:ERBB2(isoform synonym)|uniprotkb:HER2(isoform synonym)|uniprotkb:ERBB2(gene name)|psi-mi:ERBB2(display_short)|uniprotkb:HER2(gene name synonym)|uniprotkb:MLN19(gene name synonym)|uniprotkb:NEU(gene name synonym)|uniprotkb:NGL(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664909|imex:IM-26494-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000141736(gene)|ensembl:ENST00000269571(transcript)|intact:EBI-641062(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:6o8GoqTQ64og/aKbzFZZMQ8gRHI9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q7KZI7-14 intact:EBI-20725289 intact:EBI-26664926|ensembl:ENSP00000423974 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q7kzi7-14(display_long)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664933|imex:IM-26494-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000072518(gene)|ensembl:ENST00000509502(transcript)|intact:EBI-516560(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:l40ZZv7fU8zH87dwxHLjiwOvUE09606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P35968-1 intact:EBI-20725289 intact:EBI-26664949|ensembl:ENSP00000263923 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p35968-1(display_long)|uniprotkb:Fetal liver kinase 1(gene name synonym)|uniprotkb:Kinase insert domain receptor(gene name synonym)|uniprotkb:Protein-tyrosine kinase receptor flk-1(gene name synonym)|uniprotkb:KDR(gene name)|psi-mi:KDR(display_short)|uniprotkb:FLK1(gene name synonym)|uniprotkb:VEGFR2(gene name synonym)|uniprotkb:mbVegfr-2(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664959|imex:IM-26494-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000128052(gene)|ensembl:ENST00000263923(transcript)|intact:EBI-1005487(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:NnrnIZM28U6DGKYiDT9+sh/fi8Y9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q16513-1 intact:EBI-20725289 intact:EBI-26664969 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q16513-1(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664977|imex:IM-26494-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - uniprotkb:Q16513-1(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P12931-1 intact:EBI-20725289 intact:EBI-26664987|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p12931-1(display_long)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)|uniprotkb:pp60c-src(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26664994|imex:IM-26494-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|intact:EBI-621482(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P36888-1 intact:EBI-20725289 intact:EBI-26665010|ensembl:ENSP00000241453 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p36888-1(display_long)|uniprotkb:FL cytokine receptor(gene name synonym)|uniprotkb:Fetal liver kinase-2(gene name synonym)|uniprotkb:Fms-like tyrosine kinase 3(gene name synonym)|uniprotkb:Stem cell tyrosine kinase 1(gene name synonym)|uniprotkb:FLT3(gene name)|psi-mi:FLT3(display_short)|uniprotkb:CD135(gene name synonym)|uniprotkb:FLK2(gene name synonym)|uniprotkb:STK1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665019|imex:IM-26494-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000122025(gene)|ensembl:ENST00000241453(transcript)|intact:EBI-3946257(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:Y9liE/Q9llf3LbnOegBdnVXZk3c9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P49841-2 intact:EBI-20725289 intact:EBI-15870655|ensembl:ENSP00000324806 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p49841-2(display_long)|uniprotkb:GSK3B(gene name)|psi-mi:GSK3B(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)|uniprotkb:GSK-3beta2(isoform synonym)|uniprotkb:neuron-specific(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665029|imex:IM-26494-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000082701(gene)|ensembl:ENST00000316626(transcript)|intact:EBI-373586(isoform-parent)|uniprotkb:P49841-2(isoform-parent) - - isoform-comment:May play a specific role in axon growth and neurite outgrowth. Reduced binding to AXIN1, reduced ability to phosphorylate MAPT/TAU. figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:+mnJKZPToE+39AUZVr1Svxn6dvQ9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P08631-1 intact:EBI-20725289 intact:EBI-25505953|ensembl:ENSP00000365012 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p08631-1(display_long)|uniprotkb:Hematopoietic cell kinase(gene name synonym)|uniprotkb:Hemopoietic cell kinase(gene name synonym)|uniprotkb:p59-HCK/p60-HCK(gene name synonym)|uniprotkb:p59Hck(gene name synonym)|uniprotkb:p61Hck(gene name synonym)|uniprotkb:p60-HCK(isoform synonym)|uniprotkb:p61Hck(isoform synonym)|uniprotkb:HCK(gene name)|psi-mi:HCK(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665039|imex:IM-26494-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000101336(gene)|ensembl:ENST00000375852(transcript)|intact:EBI-346340(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:0ppUsdZNQdUtoKG6MdfS1bzOgZc9606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q02779 intact:EBI-20725289 intact:EBI-3392815|intact:EBI-28971541|ensembl:ENSP00000253055|uniprotkb:Q12761|uniprotkb:Q14871 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:m3k10_human(display_long)|uniprotkb:MAP3K10(gene name)|psi-mi:MAP3K10(display_short)|uniprotkb:MLK2(gene name synonym)|uniprotkb:MST(gene name synonym)|uniprotkb:Mixed lineage kinase 2(gene name synonym)|uniprotkb:Protein kinase MST(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665049|imex:IM-26494-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000253055|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015785(Mitogen activated protein kinase kinase kinase-like)|interpro:IPR016231(Mitogen-activated protein kinase kinase kinase, 9/10/11)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035779|interpro:IPR036028|rcsb pdb:2RF0|ensembl:ENSG00000130758(gene)|ensembl:ENST00000253055(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|refseq:NP_002437.2 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:4gyZrxPZDDLpl0LzZYUNiS5epx89606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P29320-1 intact:EBI-20725289 intact:EBI-15809425|ensembl:ENSP00000337451 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p29320-1(display_long)|uniprotkb:EPH-like kinase 4(gene name synonym)|uniprotkb:Tyrosine-protein kinase TYRO4(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor ETK1(gene name synonym)|uniprotkb:EPHA3(gene name)|psi-mi:EPHA3(display_short)|uniprotkb:ETK(gene name synonym)|uniprotkb:ETK1(gene name synonym)|uniprotkb:HEK(gene name synonym)|uniprotkb:TYRO4(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665059|imex:IM-26494-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1641575(isoform-parent)|ensembl:ENSG00000044524(gene)|ensembl:ENST00000336596(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:YtQaP5rZsiJHmhpkXDelGBeL8e49606 - false biotin tag:?-?|tag:?-? his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O75937 intact:EBI-20725289 intact:EBI-1045911|uniprotkb:Q6IBA4|uniprotkb:Q8N4Z5|uniprotkb:Q9P051|uniprotkb:Q9P067|uniprotkb:D3DPM0|uniprotkb:B4DUU4|intact:EBI-28966785|ensembl:ENSP00000263697|ensembl:ENSP00000494062 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:dnjc8_human(display_long)|uniprotkb:Splicing protein spf31(gene name synonym)|uniprotkb:DNAJC8(gene name)|psi-mi:DNAJC8(display_short)|uniprotkb:SPF31(gene name synonym)|uniprotkb:HSPC315(orf name)|uniprotkb:HSPC331(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665069|imex:IM-26494-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000263697|ensembl:ENSP00000494062|ensembl:ENSG00000126698(gene)|ensembl:ENSG00000285317(gene)|ensembl:ENST00000263697(transcript)|ensembl:ENST00000645856(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0045171"(intercellular bridge)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869|interpro:IPR042858|mint:O75937|reactome:R-HSA-72163|refseq:NP_055095.2 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:muJkeaOMc4UXHR4DPNuQeciq7PI9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O60828-1 intact:EBI-20725289 intact:EBI-26665079|ensembl:ENSP00000218224|ensembl:ENSP00000365747|ensembl:ENSP00000379985|ensembl:ENSP00000391759|ensembl:ENSP00000498362 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o60828-1(display_long)|uniprotkb:38 kDa nuclear protein containing a WW domain(gene name synonym)|uniprotkb:Polyglutamine tract-binding protein 1(gene name synonym)|uniprotkb:JM26(orf name)|uniprotkb:PQBP-1(isoform synonym)|uniprotkb:PQBP1(gene name)|psi-mi:PQBP1(display_short)|uniprotkb:NPW38(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665088|imex:IM-26494-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000102103(gene)|ensembl:ENST00000218224(transcript)|ensembl:ENST00000376563(transcript)|ensembl:ENST00000396763(transcript)|ensembl:ENST00000447146(transcript)|ensembl:ENST00000651767(transcript)|intact:EBI-713867(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:E4tMCoGbaqAfjU8QXbQzbAb8fGQ9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q14444-1 intact:EBI-20725289 intact:EBI-5455573|ensembl:ENSP00000340329|ensembl:ENSP00000434150 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q14444-1(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665099|imex:IM-26494-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000135387(gene)|ensembl:ENST00000341394(transcript)|ensembl:ENST00000532820(transcript)|intact:EBI-1047080(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q86Y22-1 intact:EBI-20725289 intact:EBI-26665129|ensembl:ENSP00000375069 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q86y22-1(display_long)|uniprotkb:COL23A1(gene name)|psi-mi:COL23A1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665135|imex:IM-26494-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000050767(gene)|ensembl:ENST00000390654(transcript)|intact:EBI-373279(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:71So+BK+c8W91thK9ry9/AqRqDo9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q13442 intact:EBI-20725289 intact:EBI-1390763|uniprotkb:Q92906|uniprotkb:D6W5S5|ensembl:ENSP00000222968 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:hap28_human(display_long)|uniprotkb:PDGF-associated protein(gene name synonym)|uniprotkb:PDGFA-associated protein 1(gene name synonym)|uniprotkb:PDAP1(gene name)|psi-mi:PDAP1(display_short)|uniprotkb:HASPP28(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665145|imex:IM-26494-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_055706.1|ensembl:ENSG00000106244(gene)|ensembl:ENST00000350498(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019380|interpro:IPR039876|mint:Q13442|reactome:R-HSA-6798695 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:8oY/0PM5kBr34vOdRXuGjIVFMgU9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9UHB7-1 intact:EBI-20725289 intact:EBI-26665156|ensembl:ENSP00000265343 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9uhb7-1(display_long)|uniprotkb:ALL1-fused gene from chromosome 5q31 protein(gene name synonym)|uniprotkb:Major CDK9 elongation factor-associated protein(gene name synonym)|uniprotkb:HSPC092(orf name)|uniprotkb:AFF4(gene name)|psi-mi:AFF4(display_short)|uniprotkb:AF5Q31(gene name synonym)|uniprotkb:MCEF(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665166|imex:IM-26494-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000072364(gene)|ensembl:ENST00000265343(transcript)|intact:EBI-395282(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:JTEHIXFmAg6Y1iddSZFgzVGx7/s9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96MW1-1 intact:EBI-20725289 intact:EBI-26665176|ensembl:ENSP00000323782 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q96mw1-1(display_long)|uniprotkb:CCDC43(gene name)|psi-mi:CCDC43(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665182|imex:IM-26494-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-9247198(isoform-parent)|ensembl:ENSG00000180329(gene)|ensembl:ENST00000315286(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:QBglG4w5dKBiI8SAnoWsqpiGgvI9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q08495-1 intact:EBI-20725289 intact:EBI-26665192|ensembl:ENSP00000265800|ensembl:ENSP00000350977|ensembl:ENSP00000416111|ensembl:ENSP00000427866|ensembl:ENSP00000430609 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q08495-1(display_long)|uniprotkb:Dematin actin-binding protein(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.9(gene name synonym)|uniprotkb:Long(isoform synonym)|uniprotkb:DMTN(gene name)|psi-mi:DMTN(display_short)|uniprotkb:DMT(gene name synonym)|uniprotkb:EPB49(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665201|imex:IM-26494-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000158856(gene)|ensembl:ENST00000265800(transcript)|ensembl:ENST00000358242(transcript)|ensembl:ENST00000432128(transcript)|ensembl:ENST00000517305(transcript)|ensembl:ENST00000523266(transcript)|intact:EBI-715275(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:uXcJpVPOTFx7gMouxdx78XCOC/M9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9Y624-1 intact:EBI-20725289 intact:EBI-26665211|ensembl:ENSP00000357005 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9y624-1(display_long)|uniprotkb:Junctional adhesion molecule 1(gene name synonym)|uniprotkb:Platelet F11 receptor(gene name synonym)|uniprotkb:Platelet adhesion molecule 1(gene name synonym)|uniprotkb:UNQ264/PRO301(orf name)|uniprotkb:F11R(gene name)|psi-mi:F11R(display_short)|uniprotkb:JAM1(gene name synonym)|uniprotkb:JCAM(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665220|imex:IM-26494-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000158769(gene)|ensembl:ENST00000368026(transcript)|intact:EBI-742600(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:9TaktSbIwjn9jMYlv86aB44hwes9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96B01-2 intact:EBI-20725289 intact:EBI-1178743|ensembl:ENSP00000309479 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q96b01-2(display_long)|uniprotkb:RAD51AP1(gene name)|psi-mi:RAD51AP1(display_short)|uniprotkb:PIR51(gene name synonym)|uniprotkb:RAD51-interacting protein(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665230|imex:IM-26494-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1178724(r51a1_human)|ensembl:ENSG00000111247(gene)|ensembl:ENST00000352618(transcript)|uniprotkb:Q96B01-2(isoform-parent) - - isoform-comment:"Ref.3 (AAH05973) sequence differs from that shown due to a frameshift in position 59" figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:w9KbYu0WrcKQeEQyjtodSAOjo3o9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q13303 intact:EBI-20725289 intact:EBI-948729|ensembl:ENSP00000164247|ensembl:ENSP00000367332|ensembl:ENSP00000367337|ensembl:ENSP00000400285|ensembl:ENSP00000499496|uniprotkb:Q6ZNE4|uniprotkb:A0AVM9|uniprotkb:O43659|uniprotkb:Q5TG82|uniprotkb:Q5TG83|uniprotkb:Q99411|uniprotkb:A8K1A4|uniprotkb:B0AZR7|uniprotkb:Q2YD85 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:kcab2_human(display_long)|uniprotkb:"K(+) channel subunit beta-2"(gene name synonym)|uniprotkb:Kv-beta-2(gene name synonym)|uniprotkb:KCNAB2(gene name)|psi-mi:KCNAB2(display_short)|uniprotkb:KCNA2B(gene name synonym)|uniprotkb:KCNK2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665240|imex:IM-26494-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000069424(gene)|ensembl:ENST00000164247(transcript)|ensembl:ENST00000378092(transcript)|ensembl:ENST00000378097(transcript)|ensembl:ENST00000428161(transcript)|ensembl:ENST00000671676(transcript)|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0098900"(regulation of action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1990031"(pinceau fiber)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR005399(Potassium channel, voltage-dependent, beta subunit, KCNAB-related)|interpro:IPR005401(Potassium channel, voltage-dependent, beta subunit, KCNAB2)|interpro:IPR005983(Potassium channel, voltage-dependent, beta subunit, KCNAB)|interpro:IPR023210|interpro:IPR036812|rcsb pdb:1ZSX|rcsb pdb:7EJ1|rcsb pdb:7EJ2|reactome:R-HSA-1296072|reactome:R-HSA-6798695|refseq:NP_001186789.1|refseq:NP_001186790.1|refseq:NP_001186791.1|refseq:NP_003627.1|refseq:NP_742128.1|refseq:XP_011540623.1|refseq:XP_011540624.1|refseq:XP_005263571.1|refseq:NP_001186792.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:xH22lEz6vYy0yIz7gNUS91SkeMs9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9BTC0 intact:EBI-20725289 intact:EBI-739985|uniprotkb:O15043|uniprotkb:A8MY65|uniprotkb:Q3ZTL7|uniprotkb:Q3ZTL8|uniprotkb:Q4VXS1|uniprotkb:Q4VXS2|uniprotkb:Q4VXV8|uniprotkb:Q96D72|uniprotkb:Q9BQW0|uniprotkb:Q9BW03|uniprotkb:Q9H4G6|uniprotkb:Q9H4G7|uniprotkb:Q9NTU8|uniprotkb:Q9NUM8|uniprotkb:Q9UFB6|uniprotkb:B9EH82|uniprotkb:Q4VXV9|uniprotkb:E1P5I1|intact:EBI-28975591|ensembl:ENSP00000266070|ensembl:ENSP00000378752 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:dido1_human(display_long)|uniprotkb:DIDO1(gene name)|psi-mi:DIDO1(display_short)|uniprotkb:Death-associated transcription factor 1(gene name synonym)|uniprotkb:C20orf158(gene name synonym)|uniprotkb:DATF1(gene name synonym)|uniprotkb:KIAA0333(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665250|imex:IM-26494-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000266070|ensembl:ENST00000354665|ensembl:ENSP00000346692|ensembl:ENST00000370366|ensembl:ENSP00000359391|ensembl:ENST00000370368|ensembl:ENSP00000359394|ensembl:ENST00000370371|ensembl:ENSP00000359397|ensembl:ENST00000395340|ensembl:ENSP00000378749|ensembl:ENSP00000378752|refseq:NP_001180298.1|refseq:NP_001180299.1|refseq:NP_071388.2|refseq:NP_149072.2|refseq:NP_542986.1|refseq:NP_542987.2|ensembl:ENSG00000101191(gene)|ensembl:ENST00000266070(transcript)|ensembl:ENST00000395343(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR033082|interpro:IPR036575|mint:Q9BTC0|rcsb pdb:2M3H|rcsb pdb:4L7X|reactome:R-HSA-1221632|refseq:XP_011526811.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:xtp4cq/633PxqppXYlVvameuI7M9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9H0G5 intact:EBI-20725289 intact:EBI-5464397|uniprotkb:Q6FI71|ensembl:ENSP00000247026 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:nsrp1_human(display_long)|uniprotkb:NSRP1(gene name)|psi-mi:NSRP1(display_short)|uniprotkb:CCDC55(gene name synonym)|uniprotkb:NSRP70(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 55(gene name synonym)|uniprotkb:Nuclear speckle-related protein 70(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665260|imex:IM-26494-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_115517.1|refseq:NP_001248396.1|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032502"(developmental process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018612|interpro:IPR042816|mint:Q9H0G5|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000126653(gene)|ensembl:ENST00000247026(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:Hp8MjUsGzGZWl+Y/zyzkOxjnLc49606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P35612-3 intact:EBI-20725289 intact:EBI-26665270|ensembl:ENSP00000347972 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p35612-3(display_long)|uniprotkb:ADD2(gene name)|psi-mi:ADD2(display_short)|uniprotkb:ADDB(gene name synonym)|uniprotkb:Erythrocyte adducin subunit beta(gene name synonym)|uniprotkb:Beta-4(isoform synonym)|uniprotkb:E(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665279|imex:IM-26494-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000075340(gene)|ensembl:ENST00000355733(transcript)|intact:EBI-16777913(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:pnzYhBhEV20zE/U/5sqSu0olBl49606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8IV56 intact:EBI-20725289 intact:EBI-8787485|ensembl:ENSP00000317836 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:prr15_human(display_long)|uniprotkb:PRR15(gene name)|psi-mi:PRR15(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665289|imex:IM-26494-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_011513500.1|refseq:XP_011513501.1|refseq:NP_787083.1|refseq:NP_001316925.1|refseq:NP_001316926.1|ensembl:ENSG00000176532(gene)|ensembl:ENST00000319694(transcript)|interpro:IPR028237 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:t+jer5Jqsm3x1coFVVgN0A35QGk9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P23229-2 intact:EBI-20725289 intact:EBI-21518201 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p232292(display_long)|uniprotkb:ITGA6(gene name)|psi-mi:ITGA6(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665299|imex:IM-26494-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - uniprotkb:P23229-2(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:BfxzrsGYRS882e6gvqqEtxAJrdY9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9NQC1-1 intact:EBI-20725289 intact:EBI-26665309|ensembl:ENSP00000378451 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9nqc1-1(display_long)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHF15(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665317|imex:IM-26494-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000043143(gene)|ensembl:ENST00000395003(transcript)|intact:EBI-2796167(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q16763 intact:EBI-20725289 intact:EBI-2339823|uniprotkb:Q9BTC1|ensembl:ENSP00000264552 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ube2s_human(display_long)|uniprotkb:UBE2S(gene name)|psi-mi:UBE2S(display_short)|uniprotkb:E2EPF(gene name synonym)|uniprotkb:Ubiquitin-protein ligase S(gene name synonym)|uniprotkb:Ubiquitin carrier protein S(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-24 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-EPF5(gene name synonym)|uniprotkb:OK/SW-cl.73(orf name)|uniprotkb:E2-EPF(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme S(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665328|imex:IM-26494-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_055316.2|dip:DIP-52784N|ensembl:ENSG00000108106(gene)|ensembl:ENST00000264552(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010994"(free ubiquitin chain polymerization)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051301"(cell division)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1ZDN|rcsb pdb:5BNB|rcsb pdb:5L9T|rcsb pdb:6QH3|rcsb pdb:6QHK|rcsb pdb:6S96|rcsb pdb:6S98|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-9687136|reactome:R-HSA-983168 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:PiLqBXIHRM8f6hlUXU6PkI3xNtM9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9P013 intact:EBI-20725289 intact:EBI-2371709|uniprotkb:B2RC17|uniprotkb:Q05BV9|uniprotkb:Q05DM1|uniprotkb:Q9UI29|ensembl:ENSP00000475615 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:cwc15_human(display_long)|uniprotkb:CWC15(gene name)|psi-mi:CWC15(display_short)|uniprotkb:C11orf5(gene name synonym)|uniprotkb:AD-002(orf name)|uniprotkb:HSPC148(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665338|imex:IM-26494-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_011541170.1|refseq:NP_057487.2|refseq:XP_016873405.1|ensembl:ENSG00000150316(gene)|ensembl:ENST00000279839(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006973(Cwf15/Cwc15 cell cycle control protein)|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:Sq0ehGSKIEKx1X9xv4Nx0ZiqXhk9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P11137-1 intact:EBI-20725289 intact:EBI-26665348|ensembl:ENSP00000353508|ensembl:ENSP00000507035 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p11137-1(display_long)|uniprotkb:MAP2(gene name)|psi-mi:MAP2(display_short)|uniprotkb:MAP2b(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665356|imex:IM-26494-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000078018(gene)|ensembl:ENST00000360351(transcript)|ensembl:ENST00000682079(transcript)|intact:EBI-2682460(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:IfbwC7748mUgLEmuxR5Zd2TEQ/09606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q68EM7-1 intact:EBI-20725289 intact:EBI-3957761|ensembl:ENSP00000289968|ensembl:ENSP00000500372 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q68em7-1(display_long)|uniprotkb:ARHGAP17(gene name)|psi-mi:ARHGAP17(display_short)|uniprotkb:RICH1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 17(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 1(gene name synonym)|uniprotkb:MSTP066(orf name)|uniprotkb:MSTP110(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665366|imex:IM-26494-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1642807(isoform-parent)|ensembl:ENSG00000140750(gene)|ensembl:ENSG00000288353(gene)|ensembl:ENST00000289968(transcript)|ensembl:ENST00000673560(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:ShqZATP0+ROgRhy0Afi5gqZ1JVY9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96LJ8 intact:EBI-20725289 intact:EBI-1993941|uniprotkb:Q5R386|ensembl:ENSP00000364240 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ubx10_human(display_long)|uniprotkb:UBXN10(gene name)|psi-mi:UBXN10(display_short)|uniprotkb:UBXD3(gene name synonym)|uniprotkb:UBX domain-containing protein 3(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665376|imex:IM-26494-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_011539001.1|refseq:NP_689589.1|refseq:XP_005245799.1|ensembl:ENSG00000162543(gene)|ensembl:ENST00000375099(transcript)|go:"GO:0005929"(cilium)|go:"GO:0060271"(cilium assembly)|interpro:IPR001012(UBX)|interpro:IPR029071|mint:Q96LJ8 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:qB59VesF5qlK1qZ9rMI4M2qj/xw9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O96013-1 intact:EBI-20725289 intact:EBI-15866280|ensembl:ENSP00000351049|ensembl:ENSP00000353625|ensembl:ENSP00000469413 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o96013-1(display_long)|uniprotkb:PAK4(gene name)|psi-mi:PAK4(display_short)|uniprotkb:KIAA1142(gene name synonym)|uniprotkb:p21-activated kinase 4(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665386|imex:IM-26494-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000130669(gene)|ensembl:ENST00000358301(transcript)|ensembl:ENST00000360442(transcript)|ensembl:ENST00000593690(transcript)|intact:EBI-713738(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:8i8hHt/Taj+czkueFRAMhdiMkYw9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9ULJ7-1 intact:EBI-20725289 intact:EBI-26665396|ensembl:ENSP00000425658 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9ulj7-1(display_long)|uniprotkb:ANKRD50(gene name)|psi-mi:ANKRD50(display_short)|uniprotkb:KIAA1223(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665404|imex:IM-26494-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-5653671(isoform-parent)|ensembl:ENSG00000151458(gene)|ensembl:ENST00000504087(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:cP1xkkSlKwersPLj/gvrnWOjm+89606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q02641-1 intact:EBI-20725289 intact:EBI-15707950|ensembl:ENSP00000377840 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q02641-1(display_long)|uniprotkb:CACNB1(gene name)|psi-mi:CACNB1(display_short)|uniprotkb:CACNLB1(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 1(gene name synonym)|uniprotkb:Beta-1B(isoform synonym)|uniprotkb:Beta-1b2(isoform synonym)|uniprotkb:Beta1-2(isoform synonym)|uniprotkb:BetaA(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665415|imex:IM-26494-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-947514(isoform-parent)|ensembl:ENSG00000067191(gene)|ensembl:ENST00000394303(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:nP0QYe6Gr+aIneTmyLWfPuvMEfk9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O95171 intact:EBI-20725289 intact:EBI-7543896|uniprotkb:B7Z797|intact:MINT-8162407|intact:UNK-5430852|uniprotkb:Q86X00|intact:UNK-5458327|uniprotkb:Q53H61|uniprotkb:F5H651|uniprotkb:Q5W0S8|uniprotkb:Q5W0S9|intact:MINT-3975264|ensembl:ENSP00000302579 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:scel_human(display_long)|uniprotkb:SCEL(gene name)|psi-mi:SCEL(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665425|imex:IM-26494-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_659001.2|refseq:NP_001154178.1|refseq:NP_003834.3|ensembl:ENSG00000136155(gene)|ensembl:ENST00000349847(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0008544"(epidermis development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|mint:O95171 - - comment:mint|function:May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:1sNj7h14CEpm44d5qulY/tWlYgE9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8NC51-1 intact:EBI-20725289 intact:EBI-523570|ensembl:ENSP00000360034 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q8nc51-1(display_long)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665435|imex:IM-26494-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-523558(pairb_human)|ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8IV04-1 intact:EBI-20725289 intact:EBI-15619668|ensembl:ENSP00000443654 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q8iv04-1(display_long)|uniprotkb:TBC1D10C(gene name)|psi-mi:TBC1D10C(display_short)|uniprotkb:TBC1 domain family member 10C(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665445|imex:IM-26494-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000175463(gene)|ensembl:ENST00000542590(transcript)|intact:EBI-10261452(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:GgmTrnBwUHrZks4qEWHv9PmgO1E9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q7L9B9 intact:EBI-20725289 intact:EBI-12262046|ensembl:ENSP00000242108|ensembl:ENSP00000442692|uniprotkb:Q96K64|uniprotkb:Q9C0F7 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:eepd1_human(display_long)|uniprotkb:EEPD1(gene name)|psi-mi:EEPD1(display_short)|uniprotkb:KIAA1706(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665455|imex:IM-26494-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENST00000242108(transcript)|ensembl:ENST00000534978(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0046658"(anchored component of plasma membrane)|interpro:IPR003583(Helix-hairpin-helix DNA-binding, class 1)|interpro:IPR004509(Competence protein ComEA, helix-hairpin-helix region)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR036691|reactome:R-HSA-9029569|ensembl:ENSG00000122547(gene)|refseq:NP_085139.2 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:IlvwQqQ4mWaIgHfCbILUHCaDa5c9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9BRP8-1 intact:EBI-20725289 intact:EBI-26665465|ensembl:ENSP00000386156 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9brp8-1(display_long)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665473|imex:IM-26494-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-2352802(isoform-parent)|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:A0AVK6 intact:EBI-20725289 intact:EBI-7779316|ensembl:ENSP00000250024|ensembl:ENSP00000434199|ensembl:ENSP00000481103|uniprotkb:Q8N340|uniprotkb:Q5BKY4|intact:MINT-6541611|uniprotkb:Q9H5M0|uniprotkb:Q3C1U6|uniprotkb:Q2VPJ3|uniprotkb:A8K9H3 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:e2f8_human(display_long)|uniprotkb:E2F8(gene name)|psi-mi:E2F8(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665483|imex:IM-26494-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR036388|interpro:IPR036390|mint:A0AVK6|rcsb pdb:4YO2|reactome:R-HSA-6804116|go:"GO:0070365"(hepatocyte differentiation)|ensembl:ENSG00000129173(gene)|ensembl:ENST00000250024(transcript)|ensembl:ENST00000527884(transcript)|ensembl:ENST00000620009(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001890"(placenta development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032877"(positive regulation of DNA endoreduplication)|go:"GO:0033301"(cell cycle comprising mitosis without cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060718"(chorionic trophoblast cell differentiation)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|refseq:NP_001243301.1|refseq:NP_001243300.1|refseq:NP_078956.2 - - function:Inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Modulates the activity of other E2F proteins, such as E2F1, probably by competing or displacing activating E2Fs from promoter binding|comment:mint figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:8RCzz+HuzFPNJ4soR6lxKkq17BU9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q00688 intact:EBI-20725289 intact:EBI-1044081|uniprotkb:Q14317|ensembl:ENSP00000216330|ensembl:ENSP00000379374|uniprotkb:B2R4Q9 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:fkbp3_human(display_long)|uniprotkb:FKBP3(gene name)|psi-mi:FKBP3(display_short)|uniprotkb:FKBP25(gene name synonym)|uniprotkb:FK506-binding protein 3(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP25(gene name synonym)|uniprotkb:Rapamycin-selective 25 kDa immunophilin(gene name synonym)|uniprotkb:25 kDa FK506-binding protein(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665493|imex:IM-26494-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_002004.1|ensembl:ENSG00000100442(gene)|ensembl:ENST00000216330(transcript)|ensembl:ENST00000396062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR041200|interpro:IPR043368|mint:Q00688|rcsb pdb:1PBK|rcsb pdb:2KFV|rcsb pdb:2MPH|rcsb pdb:5D75|rcsb pdb:5GPG|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:xU5FDlTZzy8veAtOaoLtQMeBsr09606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9H3H9 intact:EBI-20725289 intact:EBI-2511339|ensembl:ENSP00000332359|ensembl:ENSP00000361866|uniprotkb:B2R5C7 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:tcal2_human(display_long)|uniprotkb:TCEAL2(gene name)|psi-mi:TCEAL2(display_short)|uniprotkb:Transcription elongation factor S-II protein-like 2(gene name synonym)|uniprotkb:My048(orf name)|uniprotkb:MY0876G0(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665503|imex:IM-26494-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000184905(gene)|ensembl:ENST00000329035(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0050699"(WW domain binding)|interpro:IPR021156|ensembl:ENST00000372780(transcript)|refseq:NP_525129.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:BWeVHwMqsKSxoC6cxyUUSika3Cc9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8IV63-1 intact:EBI-20725289 intact:EBI-26665513|ensembl:ENSP00000324636|ensembl:ENSP00000469880|ensembl:ENSP00000473171 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q8iv63-1(display_long)|uniprotkb:Serine/threonine-protein pseudokinase VRK3(gene name synonym)|uniprotkb:Vaccinia-related kinase 3(gene name synonym)|uniprotkb:VRK3(gene name)|psi-mi:VRK3(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665519|imex:IM-26494-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000105053(gene)|ensembl:ENST00000316763(transcript)|ensembl:ENST00000594948(transcript)|ensembl:ENST00000599538(transcript)|intact:EBI-1058605(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:eoBtIgSkVcOE5bw/By6UEqbiO/I9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O43602-1 intact:EBI-20725289 intact:EBI-26665529|ensembl:ENSP00000489635|ensembl:ENSP00000490448 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o43602-1(display_long)|uniprotkb:Doublin(gene name synonym)|uniprotkb:Lissencephalin-X(gene name synonym)|uniprotkb:DCX(gene name)|psi-mi:DCX(display_short)|uniprotkb:DBCN(gene name synonym)|uniprotkb:LISX(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665537|imex:IM-26494-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000077279(gene)|ensembl:ENST00000496551(transcript)|ensembl:ENST00000635795(transcript)|intact:EBI-8646694(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:aWfld/VsgE+smntEf9CxZ4JdAAA9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q14019 intact:EBI-20725289 intact:EBI-79926|ensembl:ENSP00000262428|uniprotkb:Q86XM5|uniprotkb:B2RDU3|uniprotkb:D3DUL9 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:cotl1_human(display_long)|uniprotkb:COTL1(gene name)|psi-mi:COTL1(display_short)|uniprotkb:CLP(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26665548|imex:IM-26494-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000103187(gene)|ensembl:ENST00000262428(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR030502|rcsb pdb:1T2L|rcsb pdb:1T3X|rcsb pdb:1T3Y|rcsb pdb:1TMW|rcsb pdb:1VFQ|rcsb pdb:1WNJ|reactome:R-HSA-6798695|go:"GO:0003779"(actin binding)|refseq:NP_066972.1|dip:DIP-30951N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/02/22 - rogid:a98Y1D7sbXDDhPfoYSgv3pdrGmU9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q12904-1 intact:EBI-20725289 intact:EBI-26882619|ensembl:ENSP00000350699|ensembl:ENSP00000499850|ensembl:ENSP00000499921|ensembl:ENSP00000500025|ensembl:ENSP00000500159|ensembl:ENSP00000500170|ensembl:ENSP00000500620|ensembl:ENSP00000500668|ensembl:ENSP00000500732|ensembl:ENSP00000500794 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q12904-1(display_long)|uniprotkb:Multisynthase complex auxiliary component p43(gene name synonym)|uniprotkb:AIMP1(gene name)|psi-mi:AIMP1(display_short)|uniprotkb:EMAP2(gene name synonym)|uniprotkb:SCYE1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882627|imex:IM-26494-270 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000164022(gene)|ensembl:ENST00000358008(transcript)|ensembl:ENST00000671868(transcript)|ensembl:ENST00000671960(transcript)|ensembl:ENST00000672285(transcript)|ensembl:ENST00000672328(transcript)|ensembl:ENST00000672337(transcript)|ensembl:ENST00000672341(transcript)|ensembl:ENST00000672911(transcript)|ensembl:ENST00000673018(transcript)|ensembl:ENST00000673123(transcript)|intact:EBI-1045802(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:UtCeSRjFyuuEHUxVF2HkG9RA55k9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q569H4-3 intact:EBI-20725289 intact:EBI-26882649|ensembl:ENSP00000368869 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q569h4-3(display_long)|uniprotkb:Mesenchymal stem cell protein DSC54(gene name synonym)|uniprotkb:Proline-rich protein 16(gene name synonym)|uniprotkb:PRR16(gene name)|psi-mi:PRR16(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882655|imex:IM-26494-350 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-5564642(isoform-parent)|ensembl:ENSG00000184838(gene)|ensembl:ENST00000379551(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:bMY3zVviEZe11O3da2Nt7Y594co9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q86XP3 intact:EBI-20725289 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882671|imex:IM-26494-272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O00308-1 intact:EBI-20725289 intact:EBI-22124589 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o003081(display_long)|uniprotkb:WWP2(gene name)|psi-mi:WWP2(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882685|imex:IM-26494-310 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - uniprotkb:O00308-1(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:Xj0Xssn75HP9sp/tHNe4n83eHPE9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P56211-1 intact:EBI-20725289 intact:EBI-26882705|ensembl:ENSP00000249822|ensembl:ENSP00000454297|ensembl:ENSP00000455151|ensembl:ENSP00000455625 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p56211-1(display_long)|uniprotkb:ARPP19(gene name)|psi-mi:ARPP19(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882711|imex:IM-26494-312 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-5773880(isoform-parent)|ensembl:ENSG00000128989(gene)|ensembl:ENST00000249822(transcript)|ensembl:ENST00000566423(transcript)|ensembl:ENST00000567669(transcript)|ensembl:ENST00000569281(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:gDXhL8TyGWS9aOjwJeM33TRsWYo9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O14639 intact:EBI-20725289 intact:EBI-487024|uniprotkb:A6NI16|uniprotkb:Q5T6N3|uniprotkb:Q5JVV1|uniprotkb:Q15039|uniprotkb:Q68CQ9|uniprotkb:Q9BUP1|uniprotkb:Q5T6N5|uniprotkb:B3KVH2|uniprotkb:Q5T6N2|uniprotkb:A6NJ06|uniprotkb:A8MXA9|uniprotkb:Q5JVV2|ensembl:ENSP00000277895 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ablm1_human(display_long)|uniprotkb:Actin-binding LIM protein family member 1(gene name synonym)|uniprotkb:Actin-binding double zinc finger protein(gene name synonym)|uniprotkb:Limatin(gene name synonym)|uniprotkb:ABLIM1(gene name)|psi-mi:ABLIM1(display_short)|uniprotkb:ABLIM(gene name synonym)|uniprotkb:KIAA0059(gene name synonym)|uniprotkb:LIMAB1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882727|imex:IM-26494-330 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001003407.1|refseq:NP_002304.3|refseq:NP_006711.3|ensembl:ENSG00000099204(gene)|ensembl:ENST00000277895(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR028448|interpro:IPR032402|interpro:IPR036886|mint:O14639|reactome:R-HSA-418885|go:"GO:0030032"(lamellipodium assembly)|refseq:NP_001309811.1|refseq:NP_001309821.1|refseq:NP_001309822.1|refseq:NP_001309825.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:Dsx3GrmdlsYUmQvuW59NfYF7MJg9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8N8V4 intact:EBI-20725289 intact:EBI-9658517|ensembl:ENSP00000308772|ensembl:ENSP00000491748 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ans4b_human(display_long)|uniprotkb:ANKS4B(gene name)|psi-mi:ANKS4B(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:Harmonin-interacting ankyrin repeat-containing protein(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882743|imex:IM-26494-352 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_665872.2|ensembl:ENSG00000175311(gene)|ensembl:ENSG00000284290(gene)|ensembl:ENST00000311620(transcript)|ensembl:ENST00000639229(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0030154"(cell differentiation)|go:"GO:0034622"|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904106"(protein localization to microvillus)|go:"GO:1904970"(brush border assembly)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037601 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:pGaQeBCjB3U6KWj3hjBVQYNabc49606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9Y5V0 intact:EBI-20725289 intact:EBI-2690918|uniprotkb:A8K362|ensembl:ENSP00000311768|ensembl:ENSP00000427761|ensembl:ENSP00000428227|ensembl:ENSP00000428696|ensembl:ENSP00000428985|ensembl:ENSP00000430165|ensembl:ENSP00000430823 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:zn706_human(display_long)|uniprotkb:HSPC038(orf name)|uniprotkb:PNAS-113(orf name)|uniprotkb:ZNF706(gene name)|psi-mi:ZNF706(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882765|imex:IM-26494-290 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001035975.1|refseq:NP_057180.1|refseq:NP_001254637.1|refseq:NP_001254638.1|ensembl:ENSG00000120963(gene)|ensembl:ENST00000311212(transcript)|ensembl:ENST00000517844(transcript)|ensembl:ENST00000518336(transcript)|ensembl:ENST00000519882(transcript)|ensembl:ENST00000520347(transcript)|ensembl:ENST00000520984(transcript)|ensembl:ENST00000521272(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1902455"(negative regulation of stem cell population maintenance)|interpro:IPR007513(Four F5 protein)|interpro:IPR026939|reactome:R-HSA-212436 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:AfBUOZ8pX25JaH2JyvHVCtEf2349606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P35568 intact:EBI-20725289 intact:EBI-517592|intact:EBI-28983786|ensembl:ENSP00000304895 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:irs1_human(display_long)|uniprotkb:IRS1(gene name)|psi-mi:IRS1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882779|imex:IM-26494-332 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_005535.1|ensembl:ENSP00000304895|dip:DIP-523N|ensembl:ENSG00000169047(gene)|ensembl:ENST00000305123(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005901"(caveola)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:P35568|rcsb pdb:1IRS|rcsb pdb:1K3A|rcsb pdb:1QQG|rcsb pdb:2Z8C|rcsb pdb:5U1M|rcsb pdb:6BNT|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-112412|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-2219530|reactome:R-HSA-2428928|reactome:R-HSA-2586552|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-74713|reactome:R-HSA-74749|reactome:R-HSA-9603381|reactome:R-HSA-982772 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:n/9Epczwu5jOLSKCKhmIgR7CdOw9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q6P582 intact:EBI-20725289 intact:EBI-2558548|uniprotkb:Q8WVB2|uniprotkb:Q3SWV8|ensembl:ENSP00000311500 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:mzt2a_human(display_long)|uniprotkb:FAM128A(gene name synonym)|uniprotkb:MOZART2A(gene name synonym)|uniprotkb:Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A(gene name synonym)|uniprotkb:MZT2A(gene name)|psi-mi:MZT2A(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882791|imex:IM-26494-354 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001078834.1|ensembl:ENSG00000173272(gene)|ensembl:ENST00000309451(transcript)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|interpro:IPR024332|rcsb pdb:6X0V|reactome:R-HSA-380270|reactome:R-HSA-380320 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:dCqJOdxX0GGsuNM2rTxgktV4u9s9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P42025 intact:EBI-20725289 intact:EBI-367493|uniprotkb:Q53SK5|uniprotkb:Q9BRB7|uniprotkb:D3DVH2|ensembl:ENSP00000289228 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:acty_human(display_long)|uniprotkb:ACTR1B(gene name)|psi-mi:ACTR1B(display_short)|uniprotkb:Actin-related protein 1B(gene name synonym)|uniprotkb:CTRN2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882805|imex:IM-26494-292 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000115073(gene)|ensembl:ENST00000289228(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P42025|reactome:R-HSA-2132295|reactome:R-HSA-6798695|refseq:NP_005726.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:FUpYgmLV3BdkZIlZGyC6L5kR+wE9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96AT1 intact:EBI-20725289 intact:EBI-2548425|ensembl:ENSP00000296121|ensembl:ENSP00000486878|uniprotkb:A8K0I4|uniprotkb:Q96HJ8|uniprotkb:Q9ULS7 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:k1143_human(display_long)|uniprotkb:KIAA1143(gene name)|psi-mi:KIAA1143(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882820|imex:IM-26494-314 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000163807(gene)|ensembl:ENSG00000281665(gene)|ensembl:ENST00000296121(transcript)|ensembl:ENST00000627745(transcript)|interpro:IPR027911|interpro:IPR040219|refseq:NP_065747.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:E1Pc0mcNc/K+JNIAjz/VlB+GcrY9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P35221-1 intact:EBI-20725289 intact:EBI-7053242|intact:MINT-4847619|ensembl:ENSP00000304669 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p35221-1(display_long)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1a(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882836|imex:IM-26494-274 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-701918(isoform-parent)|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript) - - comment:mint figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9NSB8-2 intact:EBI-20725289 intact:EBI-12017090|ensembl:ENSP00000407634 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9nsb8-2(display_long)|uniprotkb:HOMER2(gene name)|psi-mi:HOMER2(display_short)|uniprotkb:Cupidin(gene name synonym)|uniprotkb:2a(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882852|imex:IM-26494-356 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-2126733(isoform-parent)|uniprotkb:Q9NSB8-2(isoform-parent)|ensembl:ENSG00000103942(gene)|ensembl:ENST00000450735(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:RVkMDQqia2rereKjtYoS/JsoQVA9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8TDR4 intact:EBI-20725289 intact:EBI-3923210|uniprotkb:Q96LN5|uniprotkb:Q53EW0|ensembl:ENSP00000300258|ensembl:ENSP00000501209 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:tcp1l_human(display_long)|uniprotkb:TCP10L(gene name)|psi-mi:TCP10L(display_short)|uniprotkb:TCP10-like(gene name synonym)|uniprotkb:PRED77(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882913|imex:IM-26494-294 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_653260.1|ensembl:ENSG00000242220(gene)|ensembl:ENST00000300258(transcript)|ensembl:ENST00000674156(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR026581 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:+ljQHIRk6XZaqejKeQk6uVqc+rg9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9UPQ0-1 intact:EBI-20725289 intact:EBI-25412679|ensembl:ENSP00000316891 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9upq0-1(display_long)|uniprotkb:LIMCH1(gene name)|psi-mi:LIMCH1(display_short)|uniprotkb:KIAA1102(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882925|imex:IM-26494-296 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000064042(gene)|ensembl:ENST00000313860(transcript)|intact:EBI-2687222(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:neDT1Rx97o6shpmtkOqJy31ueTA9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P55010 intact:EBI-20725289 intact:EBI-286450|uniprotkb:Q9H5N2|uniprotkb:Q9UG48|uniprotkb:Q53XB3|ensembl:ENSP00000216554|ensembl:ENSP00000376477|ensembl:ENSP00000453743 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:if5_human(display_long)|uniprotkb:EIF5(gene name)|psi-mi:EIF5(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882935|imex:IM-26494-334 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001960.2|refseq:NP_892116.2|ensembl:ENSG00000100664(gene)|ensembl:ENST00000216554(transcript)|ensembl:ENST00000392715(transcript)|ensembl:ENST00000558506(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:P55010|rcsb pdb:2E9H|rcsb pdb:2G2K|rcsb pdb:2IU1|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:lM5AZJWJOQGbxADfl8MGCx3JAXc9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q99661-1 intact:EBI-20725289 intact:EBI-26882945|ensembl:ENSP00000361298 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q99661-1(display_long)|uniprotkb:Kinesin-like protein 6(gene name synonym)|uniprotkb:Mitotic centromere-associated kinesin(gene name synonym)|uniprotkb:KIF2C(gene name)|psi-mi:KIF2C(display_short)|uniprotkb:KNSL6(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882952|imex:IM-26494-358 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1642317(isoform-parent)|ensembl:ENSG00000142945(gene)|ensembl:ENST00000372224(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:XKQr6i+9Xtdfir6V1C8PByAIg1c9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O75821 intact:EBI-20725289 intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26882962|imex:IM-26494-336 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q86TN4-2 intact:EBI-20725289 intact:EBI-12403619|ensembl:ENSP00000378051 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q86tn4-2(display_long)|uniprotkb:TRPT1(gene name)|psi-mi:TRPT1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883117|imex:IM-26494-360 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000149743(gene)|ensembl:ENST00000394547(transcript)|uniprotkb:Q86TN4-2(isoform-parent)|intact:EBI-747197(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:ehhANLUrOqBltdI7oenW0RFlbNQ9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q2TAL5-2 intact:EBI-20725289 intact:EBI-21786658 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q2tal52(display_long)|uniprotkb:SMTNL2(gene name)|psi-mi:SMTNL2(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883133|imex:IM-26494-370 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - uniprotkb:Q2TAL5-2(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:O/fdfpnyPducDFrq+6eSEK3K0uc9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q71RC2 intact:EBI-20725289 intact:EBI-2878091|ensembl:ENSP00000381490|uniprotkb:Q96NF9|uniprotkb:A8K6T1|uniprotkb:Q6ZV14|uniprotkb:Q5CZ97|uniprotkb:G5E976|uniprotkb:E9PDG5|uniprotkb:G3XAA8 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:larp4_human(display_long)|uniprotkb:LARP4(gene name)|psi-mi:LARP4(display_short)|uniprotkb:La ribonucleoprotein domain family member 4(gene name synonym)|uniprotkb:PP13296(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883143|imex:IM-26494-276 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000161813(gene)|ensembl:ENST00000398473(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR034903|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2CQK|rcsb pdb:3PKN|rcsb pdb:6I9B|refseq:XP_011536140.1|refseq:NP_001164279.1|refseq:NP_443111.4|refseq:NP_954658.2|refseq:NP_001317344.1|refseq:XP_016874240.1|refseq:XP_016874242.1|refseq:XP_016874243.1|refseq:NP_954660.1|refseq:XP_005268670.1|refseq:XP_011536141.1|refseq:XP_011536142.1|refseq:XP_011536143.1|refseq:XP_016874241.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:9FwnSJmbM08zYGHJB3l61hB1lJk9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P30419-1 intact:EBI-20725289 intact:EBI-5280246|ensembl:ENSP00000258960|ensembl:ENSP00000468424|ensembl:ENSP00000504192 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p30419-1(display_long)|uniprotkb:NMT1(gene name)|psi-mi:NMT1(display_short)|uniprotkb:NMT(gene name synonym)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 1"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883159|imex:IM-26494-372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-5280164(isoform-parent)|ensembl:ENSG00000136448(gene)|ensembl:ENST00000258960(transcript)|ensembl:ENST00000592782(transcript)|ensembl:ENST00000676828(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:eVkADRJp/cg4xIAw0ymeUZ+Vwyk9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P51397 intact:EBI-20725289 intact:EBI-719219|uniprotkb:Q9BUC9|uniprotkb:Q6FGC3|ensembl:ENSP00000230895 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:dap1_human(display_long)|uniprotkb:DAP(gene name)|psi-mi:DAP(display_short)|uniprotkb:DAP1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883176|imex:IM-26494-316 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_004385.1|ensembl:ENSG00000112977(gene)|ensembl:ENST00000230895(transcript)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070513"(death domain binding)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR024130|refseq:NP_001278892.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:UxbkczJJPYpZuJSyfbDeREm/b6o9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q15691 intact:EBI-20725289 intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883190|imex:IM-26494-278 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O15066-1 intact:EBI-20725289 intact:EBI-26883206|ensembl:ENSP00000364864 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o15066-1(display_long)|uniprotkb:HH0048(gene name synonym)|uniprotkb:Microtubule plus end-directed kinesin motor 3B(gene name synonym)|uniprotkb:KIF3B(gene name)|psi-mi:KIF3B(display_short)|uniprotkb:KIAA0359(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883213|imex:IM-26494-338 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000101350(gene)|ensembl:ENST00000375712(transcript)|intact:EBI-3931791(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:06eFJUfpcyifNpmXa2wMQQmLccg9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O00559-1 intact:EBI-20725289 intact:EBI-26883229|ensembl:ENSP00000337675|ensembl:ENSP00000379131|ensembl:ENSP00000477645 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o00559-1(display_long)|uniprotkb:EBAG9(gene name)|psi-mi:EBAG9(display_short)|uniprotkb:RCAS1(gene name synonym)|uniprotkb:Cancer-associated surface antigen RCAS1(gene name synonym)|uniprotkb:Estrogen receptor-binding fragment-associated gene 9 protein(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883236|imex:IM-26494-280 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-8787095(isoform-parent)|ensembl:ENSG00000147654(gene)|ensembl:ENST00000337573(transcript)|ensembl:ENST00000395785(transcript)|ensembl:ENST00000620557(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:/4Zg2jOkRmcxYfNTJVTcJjEx2/49606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O95684-1 intact:EBI-20725289 intact:EBI-26883252|ensembl:ENSP00000355812 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o95684-1(display_long)|uniprotkb:FGFR1 oncogene partner(gene name synonym)|uniprotkb:CEP43(gene name)|psi-mi:CEP43(display_short)|uniprotkb:FGFR1OP(gene name synonym)|uniprotkb:FOP(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883260|imex:IM-26494-340 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000213066(gene)|ensembl:ENST00000366847(transcript)|intact:EBI-1266334(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:AcqOicx3UulQVfNzo6X0XyfExcc9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P06748-1 intact:EBI-20725289 intact:EBI-354150|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p06748-1(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)|uniprotkb:Numatrin(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883278|imex:IM-26494-362 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-78579(npm_human)|uniprotkb:P06748-1(isoform-parent)|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9BRS8-1 intact:EBI-20725289 intact:EBI-26883292|ensembl:ENSP00000299213 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9brs8-1(display_long)|uniprotkb:Acheron(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 6(gene name synonym)|uniprotkb:LARP6(gene name)|psi-mi:LARP6(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883298|imex:IM-26494-342 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000166173(gene)|ensembl:ENST00000299213(transcript)|intact:EBI-21687354(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:I0q69QEBnbhtkvx2E0xbmRYg7d09606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q92541 intact:EBI-20725289 intact:EBI-1055239|uniprotkb:Q96BX6|ensembl:ENSP00000374280 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:rtf1_human(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:KIAA0252(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883318|imex:IM-26494-318 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_055953.3|ensembl:ENSG00000137815(gene)|ensembl:ENST00000389629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR004343(Plus-3)|interpro:IPR036128|mint:Q92541|rcsb pdb:2BZE|rcsb pdb:2DB9|rcsb pdb:3U1U|rcsb pdb:4L1P|rcsb pdb:4L1U|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:uWqJdVWJE0snWuZCdF0OkVWXRuI9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P09429 intact:EBI-20725289 intact:EBI-389432|uniprotkb:Q6IBE1|uniprotkb:A5D8W9|uniprotkb:Q14321|uniprotkb:Q5T7C3|ensembl:ENSP00000343040|ensembl:ENSP00000345347|ensembl:ENSP00000382417|ensembl:ENSP00000384678 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:hmgb1_human(display_long)|uniprotkb:HMGB1(gene name)|psi-mi:HMGB1(display_short)|uniprotkb:HMG1(gene name synonym)|uniprotkb:High mobility group protein 1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883330|imex:IM-26494-364 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_002119.1|refseq:NP_001300821.1|refseq:NP_001300822.1|ensembl:ENSG00000189403(gene)|ensembl:ENST00000339872(transcript)|ensembl:ENST00000341423(transcript)|ensembl:ENST00000399494(transcript)|ensembl:ENST00000405805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001654"(eye development)|go:"GO:0001773"(myeloid dendritic cell activation)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002270"(plasmacytoid dendritic cell activation)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002643"(regulation of tolerance induction)|go:"GO:0002840"(regulation of T cell mediated immune response to tumor cell)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006265"(DNA topological change)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0009986"(cell surface)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010858"(calcium-dependent protein kinase regulator activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016829"(lyase activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0017055"(negative regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0019958"(C-X-C chemokine binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032072"(regulation of restriction endodeoxyribonuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0034137"(positive regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0035868"(alphav-beta3 integrin-HMGB1 complex)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000819"(regulation of nucleotide-excision repair)|go:"GO:2001200"(positive regulation of dendritic cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR031076|interpro:IPR036910|mint:P09429|rcsb pdb:2LY4|rcsb pdb:2RTU|rcsb pdb:2YRQ|rcsb pdb:6CG0|rcsb pdb:6CIJ|rcsb pdb:6CIK|rcsb pdb:6CIL|rcsb pdb:6CIM|rcsb pdb:6OEM|rcsb pdb:6OEN|rcsb pdb:6OEO|reactome:R-HSA-1236974|reactome:R-HSA-140342|reactome:R-HSA-166058|reactome:R-HSA-445989|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5620971|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-933542|dip:DIP-24195N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:8iSPxYEMyB6thRmixTeyF5kfDbw9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9BWU0 intact:EBI-20725289 intact:EBI-1999704|uniprotkb:A6NJ39|uniprotkb:Q4KMT1|uniprotkb:Q4KMX0|uniprotkb:Q7Z5Q9|uniprotkb:Q9NVN2|ensembl:ENSP00000323837|ensembl:ENSP00000479964 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:nadap_human(display_long)|uniprotkb:SLC4A1AP(gene name)|psi-mi:SLC4A1AP(display_short)|uniprotkb:Kidney anion exchanger adapter protein(gene name synonym)|uniprotkb:Solute carrier family 4 anion exchanger member 1 adapter protein(gene name synonym)|uniprotkb:Human lung cancer oncogene 3 protein(gene name synonym)|uniprotkb:HLC3(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883340|imex:IM-26494-282 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_060628.2|ensembl:ENSG00000163798(gene)|ensembl:ENST00000326019(transcript)|ensembl:ENST00000613058(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:Q9BWU0|rcsb pdb:4H87 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:z28F2N7dfIFPIVaNMT0gb05iRNw9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O60551 intact:EBI-20725289 intact:EBI-3920273|ensembl:ENSP00000367407|uniprotkb:Q9BRB4|uniprotkb:Q5VUC8|uniprotkb:B0YJ49|uniprotkb:Q53Y38 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:nmt2_human(display_long)|uniprotkb:NMT2(gene name)|psi-mi:NMT2(display_short)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 2"(gene name synonym)|uniprotkb:Peptide N-myristoyltransferase 2(gene name synonym)|uniprotkb:Type II N-myristoyltransferase(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883350|imex:IM-26494-390 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000152465(gene)|ensembl:ENST00000378165(transcript)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0043657"(host cell)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|rcsb pdb:4C2X|rcsb pdb:6PAU|reactome:R-HSA-174490|reactome:R-HSA-2514859|refseq:NP_001295224.1|refseq:NP_004799.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:D0A45m14BXLRl69s94bURcQ2MhA9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q13283-1 intact:EBI-20725289 intact:EBI-26883360|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q13283-1(display_long)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883367|imex:IM-26494-374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000145907(gene)|ensembl:ENST00000356245(transcript)|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|intact:EBI-1047359(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q6PGN9-2 intact:EBI-20725289 intact:EBI-11019027|ensembl:ENSP00000358919|ensembl:ENSP00000358923|ensembl:ENSP00000358925|ensembl:ENSP00000386323 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q6pgn9-2(display_long)|uniprotkb:FP3214(orf name)|uniprotkb:DDA3(gene name synonym)|uniprotkb:PSRC1(gene name)|psi-mi:PSRC1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883379|imex:IM-26494-344 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-7392664(isoform-parent)|ensembl:ENSG00000134222(gene)|ensembl:ENST00000369903(transcript)|ensembl:ENST00000369907(transcript)|ensembl:ENST00000369909(transcript)|ensembl:ENST00000409267(transcript)|uniprotkb:Q6PGN9-2(isoform-parent) - - isoform-comment:Contains a phosphoserine at position 212. Contains a phosphothreonine at position 215. figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:gnHjWKnoccbpHo3PHdWumERGDAc9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9Y5S9-1 intact:EBI-20725289 intact:EBI-5773674|ensembl:ENSP00000463058|ensembl:ENSP00000488265 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9y5s9-1(display_long)|uniprotkb:RBM8A(gene name)|psi-mi:RBM8A(display_short)|uniprotkb:Binder of OVCA1-1(gene name synonym)|uniprotkb:RBM8(gene name synonym)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:RNA-binding protein Y14(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym)|uniprotkb:HSPC114(orf name)|uniprotkb:MDS014(orf name)|uniprotkb:BOV-1a(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883389|imex:IM-26494-320 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-447231(isoform-parent)|ensembl:ENST00000583313(transcript)|ensembl:ENST00000632555(transcript)|ensembl:ENSG00000265241(gene)|uniprotkb:Q9Y5S9-1(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb09606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P02545-1 intact:EBI-20725289 intact:EBI-351949|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p02545-1(display_long)|uniprotkb:Lamin A(isoform synonym)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883399|imex:IM-26494-392 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-351935(lmna_human)|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9HCH5-6 intact:EBI-20725289 intact:EBI-26883409|ensembl:ENSP00000374610|ensembl:ENSP00000435238 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9hch5-6(display_long)|uniprotkb:Breast cancer-associated antigen SGA-72M(gene name synonym)|uniprotkb:Exophilin-4(gene name synonym)|uniprotkb:SYTL2(gene name)|psi-mi:SYTL2(display_short)|uniprotkb:KIAA1597(gene name synonym)|uniprotkb:SGA72M(gene name synonym)|uniprotkb:SLP2(gene name synonym)|uniprotkb:SLP2A(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883419|imex:IM-26494-298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000137501(gene)|ensembl:ENST00000389960(transcript)|ensembl:ENST00000524452(transcript)|intact:EBI-2690103(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:9Q3Oy6VpE2R3zy5bOL85psS1Uu89606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O43566-7 intact:EBI-20725289 intact:EBI-26883431|ensembl:ENSP00000386229 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o43566-7(display_long)|uniprotkb:RGS14(gene name)|psi-mi:RGS14(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883437|imex:IM-26494-300 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000169220(gene)|ensembl:ENST00000408923(transcript)|intact:EBI-750603(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:KEcGh5F6Ml7JlltMf4YWgSBStTI9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9NYS0 intact:EBI-20725289 intact:EBI-3918452|ensembl:ENSP00000373411|ensembl:ENSP00000392307|ensembl:ENSP00000393785|ensembl:ENSP00000394214|ensembl:ENSP00000400385|ensembl:ENSP00000483749|uniprotkb:Q96K18 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:kbrs1_human(display_long)|uniprotkb:NKIRAS1(gene name)|psi-mi:NKIRAS1(display_short)|uniprotkb:KBRAS1(gene name synonym)|uniprotkb:I-kappa-B-interacting Ras-like protein 1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883457|imex:IM-26494-376 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000197885(gene)|ensembl:ENST00000388759(transcript)|ensembl:ENST00000416026(transcript)|ensembl:ENST00000421515(transcript)|ensembl:ENST00000425478(transcript)|ensembl:ENST00000443659(transcript)|ensembl:ENST00000614374(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR042227|reactome:R-HSA-1810476|reactome:R-HSA-445989|reactome:R-HSA-933542|refseq:NP_065078.1|refseq:XP_005265133.1|refseq:XP_005265134.1|refseq:XP_005265135.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:/7C1u/3+LzS3f8QVj6vxnrCYlNM9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q08752 intact:EBI-20725289 intact:EBI-716596|uniprotkb:B2R9V2|ensembl:ENSP00000303754 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ppid_human(display_long)|uniprotkb:Cyclophilin-40(gene name synonym)|uniprotkb:Cyclophilin-related protein(gene name synonym)|uniprotkb:PPID(gene name)|psi-mi:PPID(display_short)|uniprotkb:CYP40(gene name synonym)|uniprotkb:CYPD(gene name synonym)|uniprotkb:Rotamase D(gene name synonym)|uniprotkb:40 kDa peptidyl-prolyl cis-trans isomerase(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883467|imex:IM-26494-284 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_005029.1|ensembl:ENSG00000171497(gene)|ensembl:ENST00000307720(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0015031"(protein transport)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071492"(cellular response to UV-A)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR029000|reactome:R-HSA-8939211|interpro:IPR011990(Tetratricopeptide-like helical)|dip:DIP-34893N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:Vw7y4LTw7d9HE3txHGqBM0NEY5Q9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96BZ8 intact:EBI-20725289 intact:EBI-726510|uniprotkb:Q9HCU7|ensembl:ENSP00000222224|ensembl:ENSP00000477607|ensembl:ENSP00000478485|ensembl:ENSP00000479538|ensembl:ENSP00000480516|ensembl:ENSP00000481079|ensembl:ENSP00000481252|ensembl:ENSP00000481386|ensembl:ENSP00000481948|ensembl:ENSP00000483164 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:leng1_human(display_long)|uniprotkb:LENG1(gene name)|psi-mi:LENG1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883477|imex:IM-26494-346 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_077292.2|ensembl:ENSG00000105617(gene)|ensembl:ENSG00000275935(gene)|ensembl:ENSG00000276628(gene)|ensembl:ENSG00000276774(gene)|ensembl:ENSG00000277457(gene)|ensembl:ENSG00000277808(gene)|ensembl:ENSG00000278257(gene)|ensembl:ENSG00000278426(gene)|ensembl:ENSG00000278516(gene)|ensembl:ENST00000222224(transcript)|ensembl:ENST00000610998(transcript)|ensembl:ENST00000613622(transcript)|ensembl:ENST00000614037(transcript)|ensembl:ENST00000616103(transcript)|ensembl:ENST00000616816(transcript)|ensembl:ENST00000617592(transcript)|ensembl:ENST00000619669(transcript)|ensembl:ENST00000621285(transcript)|ensembl:ENST00000621927(transcript)|interpro:IPR019339|interpro:IPR039875|ensembl:ENSG00000276959(gene) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:CbwywThJZ/wcqO76EMhiG8tvJN09606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9Y6X0-1 intact:EBI-20725289 intact:EBI-26883496|ensembl:ENSP00000497406|ensembl:ENSP00000502995|ensembl:ENSP00000503094|ensembl:ENSP00000503656|ensembl:ENSP00000504398 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9y6x0-1(display_long)|uniprotkb:SETBP1(gene name)|psi-mi:SETBP1(display_short)|uniprotkb:KIAA0437(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883504|imex:IM-26494-378 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000152217(gene)|ensembl:ENST00000649279(transcript)|ensembl:ENST00000677068(transcript)|ensembl:ENST00000677077(transcript)|ensembl:ENST00000677130(transcript)|ensembl:ENST00000678152(transcript)|intact:EBI-2548259(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:bPLw8rppZYzLANH100jgHI5yfhI9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q12972-1 intact:EBI-20725289 intact:EBI-16012257|ensembl:ENSP00000311677 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q12972-1(display_long)|uniprotkb:NIPP1(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory inhibitor subunit 8(gene name synonym)|uniprotkb:PPP1R8(gene name)|psi-mi:PPP1R8(display_short)|uniprotkb:ARD1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883580|imex:IM-26494-322 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000117751(gene)|ensembl:ENST00000311772(transcript)|intact:EBI-716633(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:vvLrx9wP0nm6A4K8ibVYajoC/MA9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9UEE9-1 intact:EBI-20725289 intact:EBI-26883597|ensembl:ENSP00000283882 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9uee9-1(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883605|imex:IM-26494-324 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|intact:EBI-747834(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9UMR2-1 intact:EBI-20725289 intact:EBI-5773937|ensembl:ENSP00000288071 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9umr2-1(display_long)|uniprotkb:DBP5(gene name synonym)|uniprotkb:DDX19(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD5(gene name synonym)|uniprotkb:DEAD box protein 19B(gene name synonym)|uniprotkb:TDBP(gene name synonym)|uniprotkb:DDX19B(gene name)|psi-mi:DDX19B(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883621|imex:IM-26494-326 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000157349(gene)|ensembl:ENST00000288071(transcript)|intact:EBI-719232(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:1UiDyTWXtMNt5s6Dw86KD1xY+0o9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8IXJ9-1 intact:EBI-20725289 intact:EBI-26883657|ensembl:ENSP00000364839|ensembl:ENSP00000480487|ensembl:ENSP00000481978 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q8ixj9-1(display_long)|uniprotkb:Additional sex combs-like protein 1(gene name synonym)|uniprotkb:ASXL1(gene name)|psi-mi:ASXL1(display_short)|uniprotkb:KIAA0978(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883665|imex:IM-26494-328 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1646500(isoform-parent)|ensembl:ENSG00000171456(gene)|ensembl:ENST00000375687(transcript)|ensembl:ENST00000613218(transcript)|ensembl:ENST00000620121(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:6YpSgdOhNRawROUe3W0t72u6JfA9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q14289-1 intact:EBI-20725289 intact:EBI-26883679|ensembl:ENSP00000332816|ensembl:ENSP00000380638 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q14289-1(display_long)|uniprotkb:Calcium-dependent tyrosine kinase(gene name synonym)|uniprotkb:Calcium-regulated non-receptor proline-rich tyrosine kinase(gene name synonym)|uniprotkb:Cell adhesion kinase beta(gene name synonym)|uniprotkb:Focal adhesion kinase 2(gene name synonym)|uniprotkb:Proline-rich tyrosine kinase 2(gene name synonym)|uniprotkb:Related adhesion focal tyrosine kinase(gene name synonym)|uniprotkb:PTK2B(gene name)|psi-mi:PTK2B(display_short)|uniprotkb:FAK2(gene name synonym)|uniprotkb:PYK2(gene name synonym)|uniprotkb:RAFTK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883689|imex:IM-26494-302 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000120899(gene)|ensembl:ENST00000346049(transcript)|ensembl:ENST00000397501(transcript)|intact:EBI-298640(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/26 - rogid:rpqjaDBbtx7BK+JiIR/sBlyPLvY9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8TDD1-2 intact:EBI-20725289 intact:EBI-11035712|ensembl:ENSP00000323858 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q8tdd1-2(display_long)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DEAD box protein 54(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883706|imex:IM-26494-380 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1052503(isoform-parent)|ensembl:ENSG00000123064(gene)|ensembl:ENST00000314045(transcript)|uniprotkb:Q8TDD1-2(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:KkgGArBuS1uyON/ianfcaNRFaIQ9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P50221-1 intact:EBI-20725289 intact:EBI-16807694 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p502211(display_long)|uniprotkb:MEOX1(gene name)|psi-mi:MEOX1(display_short)|uniprotkb:MOX1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883724|imex:IM-26494-304 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - uniprotkb:P50221-1(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:yBbzuzEOADdUkAmwCSLI6+yosC09606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9H607 intact:EBI-20725289 intact:EBI-6658915|ensembl:ENSP00000215061 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ocel1_human(display_long)|uniprotkb:OCEL1(gene name)|psi-mi:OCEL1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883738|imex:IM-26494-348 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000099330(gene)|ensembl:ENST00000215061(transcript)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031182|interpro:IPR031176|refseq:NP_078854.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:ODj/Ajc/K7/YdXk9GvtWvDiYI2w9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8WYH8-1 intact:EBI-20725289 intact:EBI-26883763|ensembl:ENSP00000322142 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q8wyh8-1(display_long)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short)|uniprotkb:p28ING5(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883784|imex:IM-26494-288 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|intact:EBI-488533(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:dwJLwzNcL9866noaSFznDKeulRU9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q76L83-1 intact:EBI-20725289 intact:EBI-26883800|ensembl:ENSP00000391447 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q76l83-1(display_long)|uniprotkb:Additional sex combs-like protein 2(gene name synonym)|uniprotkb:ASXL2(gene name)|psi-mi:ASXL2(display_short)|uniprotkb:ASXH2(gene name synonym)|uniprotkb:KIAA1685(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883809|imex:IM-26494-306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000143970(gene)|ensembl:ENST00000435504(transcript)|intact:EBI-1058437(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:O3e0oxBNha1iPYIYsUBSLGP0GPQ9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P0C1Z6-1 intact:EBI-20725289 intact:EBI-26883825|ensembl:ENSP00000375639|ensembl:ENSP00000477775|ensembl:ENSP00000480169|ensembl:ENSP00000481443|ensembl:ENSP00000480353|ensembl:ENSP00000482185|ensembl:ENSP00000482785|ensembl:ENSP00000483417|ensembl:ENSP00000483971|ensembl:ENSP00000484685 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p0c1z6-1(display_long)|uniprotkb:INO80 complex subunit F(gene name synonym)|uniprotkb:Protein FB1(gene name synonym)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)|uniprotkb:INO80F(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883832|imex:IM-26494-382 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000105619(gene)|ensembl:ENSG00000273833(gene)|ensembl:ENSG00000274073(gene)|ensembl:ENSG00000275086(gene)|ensembl:ENSG00000276022(gene)|ensembl:ENSG00000276263(gene)|ensembl:ENSG00000276296(gene)|ensembl:ENSG00000276323(gene)|ensembl:ENSG00000276504(gene)|ensembl:ENSG00000278161(gene)|ensembl:ENST00000391759(transcript)|ensembl:ENST00000611514(transcript)|ensembl:ENST00000611935(transcript)|ensembl:ENST00000614788(transcript)|ensembl:ENST00000615534(transcript)|ensembl:ENST00000615620(transcript)|ensembl:ENST00000616277(transcript)|ensembl:ENST00000616798(transcript)|ensembl:ENST00000617348(transcript)|ensembl:ENST00000619581(transcript)|intact:EBI-1245626(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q12894-1 intact:EBI-20725289 intact:EBI-26883842 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q12894-1(display_long)|uniprotkb:Protein SKMC15(gene name synonym)|uniprotkb:IFRD2(gene name)|psi-mi:IFRD2(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883848|imex:IM-26494-366 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-2512448(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:ktxpbUgNcw2DWOJw8o1R4s+U3a09606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9P1W8-1 intact:EBI-20725289 intact:EBI-26883858|ensembl:ENSP00000305529 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q9p1w8-1(display_long)|uniprotkb:CD172 antigen-like family member B(gene name synonym)|uniprotkb:Signal-regulatory protein beta-2(gene name synonym)|uniprotkb:SIRPG(gene name)|psi-mi:SIRPG(display_short)|uniprotkb:SIRPB2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883865|imex:IM-26494-384 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000089012(gene)|ensembl:ENST00000303415(transcript)|intact:EBI-1268284(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:3jf/9G8F9SPikrpNKrRrd6CR4jA9606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9BYD6 intact:EBI-20725289 intact:EBI-5325394|ensembl:ENSP00000315017|uniprotkb:A6NG03|uniprotkb:Q4W5B8|uniprotkb:Q6IAG4|uniprotkb:Q96BW3|uniprotkb:Q9H793|uniprotkb:Q9NRL5 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:rm01_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein uL1m(gene name synonym)|uniprotkb:BM-022(orf name)|uniprotkb:MRPL1(gene name)|psi-mi:MRPL1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26883877|imex:IM-26494-386 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000169288(gene)|ensembl:ENST00000315567(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR005879(Ribosomal protein L1, mitochondrial)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:Q9BYD6|rcsb pdb:7A5K|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011530500.1|refseq:XP_011530501.1|refseq:NP_064621.3 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:S5t4UAM2nDToXMl6lV3gh6Ecef09606 - false biotin tag:?-?|tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9H6T3 intact:EBI-20725289 intact:EBI-356928|uniprotkb:Q6PHR5|uniprotkb:B4DRW9|ensembl:ENSP00000005386 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:rpap3_human(display_long)|uniprotkb:RPAP3(gene name)|psi-mi:RPAP3(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26884033|imex:IM-26494-308 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001139547.1|refseq:NP_001139548.1|refseq:NP_078880.2|dip:DIP-47508N|ensembl:ENSG00000005175(gene)|ensembl:ENST00000005386(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0097255"(R2TP complex)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR025986|mint:Q9H6T3|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:6EZ4|rcsb pdb:6FD7|rcsb pdb:6FDP|rcsb pdb:6FDT|rcsb pdb:6FM8|rcsb pdb:6FO1|rcsb pdb:6GXZ|rcsb pdb:6ZBK - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:pN6/ClY+oonHFRAFtpcGeZ/OTEQ9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q14320 intact:EBI-20725289 intact:EBI-2687434|uniprotkb:Q6PJH5|uniprotkb:B2R997|uniprotkb:A8KAQ4|uniprotkb:Q5HY37|ensembl:ENSP00000377225 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:fa50a_human(display_long)|uniprotkb:DXS9928E(gene name synonym)|uniprotkb:HXC26(gene name synonym)|uniprotkb:XAP5(gene name synonym)|uniprotkb:Protein HXC-26(gene name synonym)|uniprotkb:Protein XAP-5(gene name synonym)|uniprotkb:FAM50A(gene name)|psi-mi:FAM50A(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26884043|imex:IM-26494-388 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_004690.1|ensembl:ENSG00000071859(gene)|ensembl:ENST00000393600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR007005(XAP5 protein) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:dhoqStQJ476KuMntvWeA63O2ff89606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q96LR5 intact:EBI-20725289 intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26884203|imex:IM-26494-368 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/19 - rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P46527 intact:EBI-20725289 intact:EBI-519280|uniprotkb:Q16307|uniprotkb:Q9BUS6|ensembl:ENSP00000228872|ensembl:ENSP00000507272|uniprotkb:Q5U0H2 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:cdn1b_human(display_long)|uniprotkb:Cyclin-dependent kinase inhibitor p27(gene name synonym)|uniprotkb:p27Kip1(gene name synonym)|uniprotkb:CDKN1B(gene name)|psi-mi:CDKN1B(display_short)|uniprotkb:KIP1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896201|imex:IM-26494-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_004055.1|rcsb pdb:1JSU|rcsb pdb:2AST|rcsb pdb:5UQ3|rcsb pdb:6ATH|rcsb pdb:6P8E|rcsb pdb:6P8F|rcsb pdb:6P8G|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-187577|reactome:R-HSA-198323|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-5625900|reactome:R-HSA-5674400|reactome:R-HSA-6804116|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69563|reactome:R-HSA-69656|reactome:R-HSA-8849470|reactome:R-HSA-9607240|reactome:R-HSA-9617828|reactome:R-HSA-9634638|reactome:R-HSA-9661069|ensembl:ENSG00000111276(gene)|ensembl:ENST00000228872(transcript)|ensembl:ENST00000614874(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001890"(placenta development)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009749"(response to glucose)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048839"(inner ear development)|go:"GO:0051087"(chaperone binding)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090398"(cellular senescence)|go:"GO:1902746"(regulation of lens fiber cell differentiation)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905179"(negative regulation of cardiac muscle tissue regeneration)|interpro:IPR003175(Cyclin-dependent kinase inhibitor)|interpro:IPR029843|mint:P46527|rcsb pdb:1H27|dip:DIP-33341N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:UGcAvE0fJ9JmjMbh0s4ILpSzV+49606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P49916-1 intact:EBI-20725289 intact:EBI-5452765|ensembl:ENSP00000367787 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p49916-1(display_long)|uniprotkb:LIG3(gene name)|psi-mi:LIG3(display_short)|uniprotkb:DNA ligase III(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 3(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896211|imex:IM-26494-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000005156(gene)|ensembl:ENST00000378526(transcript)|intact:EBI-1753381(isoform-parent) - - isoform-comment:Produced by alternative splicing. figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:+GqYPnth9+VqCoh1TvPG4yEDLeo9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q14696-1 intact:EBI-20725289 intact:EBI-26896221|ensembl:ENSP00000482455|ensembl:ENSP00000453430|ensembl:ENSP00000261758 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q14696-1(display_long)|uniprotkb:LDLR chaperone MESD(gene name synonym)|uniprotkb:Mesoderm development LRP chaperone MESD(gene name synonym)|uniprotkb:Mesoderm development candidate 2(gene name synonym)|uniprotkb:Mesoderm development protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-61(gene name synonym)|uniprotkb:UNQ1911/PRO4369(orf name)|uniprotkb:MESD(gene name)|psi-mi:MESD(display_short)|uniprotkb:KIAA0081(gene name synonym)|uniprotkb:MESDC2(gene name synonym)|uniprotkb:MESDM(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896231|imex:IM-26494-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENST00000261758(transcript)|ensembl:ENST00000561312(transcript)|ensembl:ENST00000619987(transcript)|ensembl:ENSG00000117899(gene)|intact:EBI-6165891(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:PO/8DDUMQwmzmwLpGYdFJWIUdB09606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8WWH5 intact:EBI-20725289 intact:EBI-6658513|ensembl:ENSP00000298746|uniprotkb:Q53ES2|uniprotkb:B2R716 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:trub1_human(display_long)|uniprotkb:TRUB1(gene name)|psi-mi:TRUB1(display_short)|uniprotkb:PUS4(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896241|imex:IM-26494-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000165832(gene)|ensembl:ENST00000298746(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR014780(tRNA pseudouridine synthase B, N-terminal, bacterial-type)|interpro:IPR020103|refseq:NP_631908.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:gjrCu9R/KVmdnMW7pbffs6CISwI9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q16644 intact:EBI-20725289 intact:EBI-1384657|uniprotkb:B5BU67|ensembl:ENSP00000350639|ensembl:ENSP00000396467|ensembl:ENSP00000478922 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:mapk3_human(display_long)|uniprotkb:Chromosome 3p kinase(gene name synonym)|uniprotkb:MAPKAPK3(gene name)|psi-mi:MAPKAPK3(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896251|imex:IM-26494-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_004626.1|refseq:NP_001230854.1|refseq:NP_001230855.1|reactome:R-HSA-2559580|reactome:R-HSA-4420097|reactome:R-HSA-450302|ensembl:ENSG00000114738(gene)|ensembl:ENST00000357955(transcript)|ensembl:ENST00000446044(transcript)|ensembl:ENST00000621469(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044351"(macropinocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|mint:Q16644|rcsb pdb:3FHR|rcsb pdb:3FXW|rcsb pdb:3R1N|rcsb pdb:3SHE|reactome:R-HSA-171007 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:pb+7uZ1B8LMFi5DrfRi70X9Xbks9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9UQB8 intact:EBI-20725289 intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896261|imex:IM-26494-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q99469 intact:EBI-20725289 intact:EBI-2652799|uniprotkb:B2R8S8|ensembl:ENSP00000273183 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:stac_human(display_long)|uniprotkb:STAC(gene name)|psi-mi:STAC(display_short)|uniprotkb:Src homology 3 and cysteine-rich domain-containing protein(gene name synonym)|uniprotkb:STAC1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896271|imex:IM-26494-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_003140.1|ensembl:ENSG00000144681(gene)|ensembl:ENST00000273183(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0030315"(T-tubule)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR001452(Src homology-3)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR035508|interpro:IPR036028|interpro:IPR039688|mint:Q99469|rcsb pdb:2DL4|rcsb pdb:6B25 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:8RqTwCIcB04azYqRuxegTSYkVf09606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O94811 intact:EBI-20725289 intact:EBI-3927802|ensembl:ENSP00000353785 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:tppp_human(display_long)|uniprotkb:TPPP(gene name)|psi-mi:TPPP(display_short)|uniprotkb:TPPP1(gene name synonym)|uniprotkb:25 kDa brain-specific protein(gene name synonym)|uniprotkb:TPPP/p25(gene name synonym)|uniprotkb:p24(gene name synonym)|uniprotkb:p25-alpha(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896281|imex:IM-26494-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000171368(gene)|ensembl:ENST00000360578(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0015631"(tubulin binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032288"(myelin assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051418"(microtubule nucleation by microtubule organizing center)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0150051"(postsynaptic Golgi apparatus)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|interpro:IPR008907(P25-alpha)|interpro:IPR011992(EF-Hand type)|interpro:IPR030792|mint:O94811|refseq:XP_005248294.2|refseq:NP_008961.1|refseq:XP_016864483.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:f7JDiVZTcTNdZeHJjWoGIeP3bvg9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O95466-1 intact:EBI-20725289 intact:EBI-26896291|ensembl:ENSP00000329219 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o95466-1(display_long)|uniprotkb:CLL-associated antigen KW-13(gene name synonym)|uniprotkb:Leukocyte formin(gene name synonym)|uniprotkb:FMNL1alpha(isoform synonym)|uniprotkb:FMNL1(gene name)|psi-mi:FMNL1(display_short)|uniprotkb:C17orf1(gene name synonym)|uniprotkb:C17orf1B(gene name synonym)|uniprotkb:FMNL(gene name synonym)|uniprotkb:FRL1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896303|imex:IM-26494-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000184922(gene)|ensembl:ENST00000331495(transcript)|intact:EBI-720020(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:SN1xgeqb5yPUjiaEv2H/kyDrD4c9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P05114 intact:EBI-20725289 intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896313|imex:IM-26494-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q6UWU2-1 intact:EBI-20725289 intact:EBI-26896323|ensembl:ENSP00000295759|ensembl:ENSP00000375939 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q6uwu2-1(display_long)|uniprotkb:GLB1L(gene name)|psi-mi:GLB1L(display_short)|uniprotkb:UNQ229/PRO262(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896330|imex:IM-26494-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000163521(gene)|ensembl:ENST00000295759(transcript)|ensembl:ENST00000392089(transcript)|intact:EBI-4311622(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:pm8Iv1eqSYc2azRlgBxM20XkcYo9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8TBX8-1 intact:EBI-20725289 intact:EBI-26896340|ensembl:ENSP00000347032|ensembl:ENSP00000439878 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q8tbx8-1(display_long)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II gamma(gene name synonym)|uniprotkb:PIP4K2C(gene name)|psi-mi:PIP4K2C(display_short)|uniprotkb:PIP5K2C(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896347|imex:IM-26494-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1383637(isoform-parent)|ensembl:ENST00000540759(transcript)|ensembl:ENSG00000166908(gene)|ensembl:ENST00000354947(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:vC4KtXa6EcyihfFZdCAb3GmQUhs9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q5BJF6-3 intact:EBI-20725289 intact:EBI-26896357|ensembl:ENSP00000377161|ensembl:ENSP00000394506 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q5bjf6-3(display_long)|uniprotkb:Cenexin(gene name synonym)|uniprotkb:Outer dense fiber of sperm tails protein 2(gene name synonym)|uniprotkb:Cenexin 1(isoform synonym)|uniprotkb:ODF2(gene name)|psi-mi:ODF2(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896364|imex:IM-26494-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000136811(gene)|ensembl:ENST00000393527(transcript)|ensembl:ENST00000444119(transcript)|intact:EBI-8744243(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:5nTd7W6UCkS6fldQXpxGwtXTvWM9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9Y6X8 intact:EBI-20725289 intact:EBI-948566|ensembl:ENSP00000314709 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:zhx2_human(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:ZHX2(gene name)|psi-mi:ZHX2(display_short)|uniprotkb:AFR1(gene name synonym)|uniprotkb:KIAA0854(gene name synonym)|uniprotkb:RAF(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896374|imex:IM-26494-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000178764(gene)|ensembl:ENST00000314393(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060040"(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|rcsb pdb:2DMP|rcsb pdb:3NAU|refseq:NP_055758.1|refseq:XP_011515233.1|refseq:XP_011515234.1|refseq:XP_005250893.1|refseq:XP_005250894.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:E8GZEZG6tlb2fHpC+xgJoP8D85Y9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P50570-1 intact:EBI-20725289 intact:EBI-26896384|ensembl:ENSP00000347890 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p50570-1(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896391|imex:IM-26494-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|intact:EBI-346547(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O00515 intact:EBI-20725289 intact:EBI-2880585|ensembl:ENSP00000375829|uniprotkb:Q96GD8|uniprotkb:O95614 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:lad1_human(display_long)|uniprotkb:LAD1(gene name)|psi-mi:LAD1(display_short)|uniprotkb:LAD(gene name synonym)|uniprotkb:Linear IgA disease antigen(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896401|imex:IM-26494-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENST00000391967(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005604"(basement membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR017404(Ladinin 1)|mint:O00515|ensembl:ENSG00000159166(gene)|refseq:NP_005549.2 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:C58/NEfIlDj38lGEIsWtqBNuSis9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q13057-1 intact:EBI-20725289 intact:EBI-26896411|ensembl:ENSP00000377406|ensembl:ENSP00000393564 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q13057-1(display_long)|uniprotkb:NBP(gene name synonym)|uniprotkb:POV-2(gene name synonym)|uniprotkb:PSEC0106(orf name)|uniprotkb:CoASy alpha(isoform synonym)|uniprotkb:COASY(gene name)|psi-mi:COASY(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896419|imex:IM-26494-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000068120(gene)|ensembl:ENST00000393818(transcript)|ensembl:ENST00000421097(transcript)|intact:EBI-745967(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:yMK1IODpj01+JZsNsayJCgEHpyo9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q15059-1 intact:EBI-20725289 intact:EBI-22033351|ensembl:ENSP00000305918 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q15059-1(display_long)|uniprotkb:RING3-like protein(gene name synonym)|uniprotkb:BRD3(gene name)|psi-mi:BRD3(display_short)|uniprotkb:KIAA0043(gene name synonym)|uniprotkb:RING3L(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896429|imex:IM-26494-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1383460(isoform-parent)|ensembl:ENSG00000169925(gene)|ensembl:ENST00000303407(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:RIwhmbGQ4NziOcjy4M80p+TY1OQ9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8N4Y2-3 intact:EBI-20725289 intact:EBI-11982645|ensembl:ENSP00000409256|ensembl:ENSP00000432334 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q8n4y2-3(display_long)|uniprotkb:CRACR2B(gene name)|psi-mi:CRACR2B(display_short)|uniprotkb:Calcium release-activated calcium channel regulator 2B(gene name synonym)|uniprotkb:Calcium release-activated channel regulator 2B(gene name synonym)|uniprotkb:EFCAB4A(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896439|imex:IM-26494-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - uniprotkb:Q8N4Y2-3(isoform-parent)|intact:EBI-10267893(isoform-parent)|ensembl:ENSG00000177685(gene)|ensembl:ENST00000528542(transcript)|ensembl:ENST00000450448(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:76w0B5349e/QlU4aMfv4UAGek8I9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O75815-1 intact:EBI-20725289 intact:EBI-15953103|ensembl:ENSP00000260502|ensembl:ENSP00000359263|ensembl:ENSP00000359264 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:o75815-1(display_long)|uniprotkb:BCAR3(gene name)|psi-mi:BCAR3(display_short)|uniprotkb:NSP2(gene name synonym)|uniprotkb:SH2D3B(gene name synonym)|uniprotkb:UNQ271/PRO308(orf name)|uniprotkb:SH2 domain-containing protein 3B(gene name synonym)|uniprotkb:Novel SH2-containing protein 2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896449|imex:IM-26494-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-702336(isoform-parent)|uniprotkb:O75815-1(isoform-parent)|ensembl:ENSG00000137936(gene)|ensembl:ENST00000260502(transcript)|ensembl:ENST00000370243(transcript)|ensembl:ENST00000370244(transcript) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:r4mh2ZDGa0AleYRBV+oAiDds1+w9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P38432 intact:EBI-20725289 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896459|imex:IM-26494-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9UN70 intact:EBI-20725289 intact:EBI-2681692|uniprotkb:Q9Y5C4|uniprotkb:Q08192|uniprotkb:O60622|ensembl:ENSP00000312070 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:pcdgk_human(display_long)|uniprotkb:PCDH2(gene name synonym)|uniprotkb:Protocadherin-2(gene name synonym)|uniprotkb:Protocadherin-43(gene name synonym)|uniprotkb:PCDHGC3(gene name)|psi-mi:PCDHGC3(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896469|imex:IM-26494-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_002579.2|refseq:NP_115778.1|ensembl:ENSG00000240184(gene)|ensembl:ENST00000308177(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016020"(membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0050808"(synapse organization)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR030728|interpro:IPR031904|interpro:IPR032455 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:P/DoxMq8JfaXjZefjqhhXGT+2V89606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q6DCA0 intact:EBI-20725289 intact:EBI-5774304|uniprotkb:B4E276|ensembl:ENSP00000272647|ensembl:ENSP00000376726 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:amerl_human(display_long)|uniprotkb:AMMECR1L(gene name)|psi-mi:AMMECR1L(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896479|imex:IM-26494-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001186069.1|refseq:NP_113633.2|ensembl:ENSG00000144233(gene)|ensembl:ENST00000272647(transcript)|ensembl:ENST00000393001(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR002733(AMMECR1)|interpro:IPR023473|interpro:IPR027485|interpro:IPR036071 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:jJvwBNzZ9acbrtTddeTmrbN76FU9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q14202-1 intact:EBI-20725289 intact:EBI-26896489|ensembl:ENSP00000322845 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q14202-1(display_long)|uniprotkb:Zinc finger protein 261(gene name synonym)|uniprotkb:ZMYM3(gene name)|psi-mi:ZMYM3(display_short)|uniprotkb:DXS6673E(gene name synonym)|uniprotkb:KIAA0385(gene name synonym)|uniprotkb:ZNF261(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896499|imex:IM-26494-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000147130(gene)|ensembl:ENST00000314425(transcript)|intact:EBI-2556139(isoform-parent) - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:pNPpauiC3Qk1EB3mevtM9L/+g0A9606 - false tag:?-?|biotin tag:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q14563 intact:EBI-20725289 intact:EBI-26610586|ensembl:ENSP00000265362|ensembl:ENSP00000415260 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:sem3a_human(display_long)|uniprotkb:Semaphorin III(gene name synonym)|uniprotkb:SEMA3A(gene name)|psi-mi:SEMA3A(display_short)|uniprotkb:SEMAD(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896509|imex:IM-26494-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000075213(gene)|ensembl:ENST00000265362(transcript)|ensembl:ENST00000436949(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021675"(nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021828"(gonadotrophin-releasing hormone neuronal migration to the hypothalamus)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036486"(ventral trunk neural crest cell migration)|go:"GO:0038191"(neuropilin binding)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0048880"(sensory system development)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0060385"(axonogenesis involved in innervation)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061551"(trigeminal ganglion development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0097490"(sympathetic neuron projection extension)|go:"GO:0097491"(sympathetic neuron projection guidance)|go:"GO:0150020"(basal dendrite arborization)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1902285"(semaphorin-plexin signaling pathway involved in neuron projection guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1903045"(neural crest cell migration involved in sympathetic nervous system development)|go:"GO:1903375"(facioacoustic ganglion development)|go:"GO:2000020"(positive regulation of male gonad development)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|interpro:IPR042820|mint:Q14563|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|dip:DIP-5744N|refseq:NP_006071.1|refseq:XP_005250167.1|refseq:XP_005250168.1|refseq:XP_006715902.1|refseq:XP_011514036.1|refseq:XP_016867162.1 - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:LrzZi1ccIRowKEYyzaG9pQco39E9606 - false tag:?-?|biotin tag:?-? his tag:n-n|fc-igg1:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9WVB4 intact:EBI-20725289 intact:EBI-26896540|ensembl:ENSMUSP00000066857|uniprotkb:B1ATW4 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:slit3_mouse(display_long)|uniprotkb:Slit3(gene name)|psi-mi:Slit3(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896587|imex:IM-26494-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000056427(gene)|ensembl:ENSMUST00000069837(transcript)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051414"(response to cortisol)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|reactome:R-MMU-376176|refseq:NP_035542.2 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:5A7E8bJae0tQlsc44F/I1h02JBA10090 - false biotin tag:?-?|tag:?-? his tag:c-c|sufficient binding region:27-901 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P70211-1 intact:EBI-20725289 intact:EBI-15755366|ensembl:ENSMUSP00000110593 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p70211-1(display_long)|uniprotkb:Dcc(gene name)|psi-mi:Dcc(display_short)|uniprotkb:Tumor suppressor protein DCC(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896597|imex:IM-26494-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-1798863(isoform-parent)|ensembl:ENSMUSG00000060534(gene)|ensembl:ENSMUST00000114943(transcript) - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:EMyR8LhWLCvJIBIAEn9dULe8Xfo10090 - false biotin tag:?-?|tag:?-? his tag:c-c|fc-igg1:c-c|sufficient binding region:1-1097 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O88632 intact:EBI-20725289 intact:EBI-26896611|ensembl:ENSMUSP00000141865|uniprotkb:E9QNC5|uniprotkb:O88633 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:sem3f_mouse(display_long)|uniprotkb:Semaphorin IV(gene name synonym)|uniprotkb:Sema3f(gene name)|psi-mi:Sema3f(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896660|imex:IM-26494-467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000034684(gene)|ensembl:ENSMUST00000192727(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021675"(nerve development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036486"(ventral trunk neural crest cell migration)|go:"GO:0040011"(locomotion)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0097490"(sympathetic neuron projection extension)|go:"GO:0097491"(sympathetic neuron projection guidance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1902285"(semaphorin-plexin signaling pathway involved in neuron projection guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001298080.1|refseq:NP_035479.2|refseq:XP_006511739.1|refseq:XP_017168717.1 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 - rogid:JIfOdCDyp8+wLXEdM/7MTgasRPc10090 - false biotin tag:?-?|tag:?-? sufficient binding region:19-775|fc-igg1:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q9P270 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-3959887|uniprotkb:A8K4P1|uniprotkb:Q8N5R3|ensembl:ENSP00000264313 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:slai2_human(display_long)|uniprotkb:SLAIN2(gene name)|psi-mi:SLAIN2(display_short)|uniprotkb:KIAA1458(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896712|imex:IM-26494-479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 refseq:NP_065897.1|ensembl:ENSG00000109171(gene)|ensembl:ENST00000264313(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR026179|mint:Q9P270|rcsb pdb:3RDV - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:r8OlU6BASEpehSYkbA9b3F3q5go9606 rigid:ohbPxrE5jYxC6lTKqxrqtuTiNN0 false his tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q96LJ8 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-1993941|uniprotkb:Q5R386|ensembl:ENSP00000364240 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:ubx10_human(display_long)|uniprotkb:UBXN10(gene name)|psi-mi:UBXN10(display_short)|uniprotkb:UBXD3(gene name synonym)|uniprotkb:UBX domain-containing protein 3(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896756|imex:IM-26494-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 refseq:XP_011539001.1|refseq:NP_689589.1|refseq:XP_005245799.1|ensembl:ENSG00000162543(gene)|ensembl:ENST00000375099(transcript)|go:"GO:0005929"(cilium)|go:"GO:0060271"(cilium assembly)|interpro:IPR001012(UBX)|interpro:IPR029071|mint:Q96LJ8 - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:qB59VesF5qlK1qZ9rMI4M2qj/xw9606 rigid:qS3m6POYzcnCMQ/hI7s8Ku5bSLg false his tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q9UBZ4 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-742588|uniprotkb:Q9Y5X7|ensembl:ENSP00000364126 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:apex2_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 2(gene name synonym)|uniprotkb:APEX nuclease 2(gene name synonym)|uniprotkb:APEX nuclease-like 2(gene name synonym)|uniprotkb:AP endonuclease XTH2(gene name synonym)|uniprotkb:APEX2(gene name)|psi-mi:APEX2(display_short)|uniprotkb:APE2(gene name synonym)|uniprotkb:APEXL2(gene name synonym)|uniprotkb:XTH2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896764|imex:IM-26494-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 refseq:NP_055296.2|go:"GO:0004519"(endonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006284"(base-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR020847|interpro:IPR036691|ensembl:ENSG00000169188(gene)|ensembl:ENST00000374987(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity") - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:QJEwQWbkLhf2cixDOWo024QN29M9606 rigid:bvbA6EMAp7fvGPX84hrbtWcYk3I false his tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q14722-1 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-22197468|ensembl:ENSP00000419952 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:q14722-1(display_long)|uniprotkb:"K(+) channel subunit beta-1"(gene name synonym)|uniprotkb:Kv-beta-1(gene name synonym)|uniprotkb:KCNAB1(gene name)|psi-mi:KCNAB1(display_short)|uniprotkb:KCNA1B(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896772|imex:IM-26494-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 intact:EBI-1642508(isoform-parent)|ensembl:ENSG00000169282(gene)|ensembl:ENST00000490337(transcript) - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:Er/E2csvNMFtZmI5s64uce21dcM9606 rigid:49f7E/hWTVxnbwZb7uw5t7hxPXk false his tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q6NUN7-2 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-26896780|ensembl:ENSP00000307695 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:q6nun7-2(display_long)|uniprotkb:JHY(gene name)|psi-mi:JHY(display_short)|uniprotkb:C11orf63(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896787|imex:IM-26494-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 ensembl:ENSG00000109944(gene)|ensembl:ENST00000307257(transcript)|intact:EBI-6660304(isoform-parent) - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:e7SGBq4xW3m8vEImLedmHn4ni9I9606 rigid:oEIlm4ZLYsTo0XQvalA/nj5y0Vg false his tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q8TDR4 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-3923210|uniprotkb:Q96LN5|uniprotkb:Q53EW0|ensembl:ENSP00000300258|ensembl:ENSP00000501209 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:tcp1l_human(display_long)|uniprotkb:TCP10L(gene name)|psi-mi:TCP10L(display_short)|uniprotkb:TCP10-like(gene name synonym)|uniprotkb:PRED77(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896795|imex:IM-26494-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 refseq:NP_653260.1|ensembl:ENSG00000242220(gene)|ensembl:ENST00000300258(transcript)|ensembl:ENST00000674156(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR026581 - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:+ljQHIRk6XZaqejKeQk6uVqc+rg9606 rigid:sn8/eiNs8zPLAJnlmciDUl57HVQ false his tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q13303-1 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-26896803|ensembl:ENSP00000400285|ensembl:ENSP00000499496|ensembl:ENSP00000164247|ensembl:ENSP00000367332|ensembl:ENSP00000367337 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:q13303-1(display_long)|uniprotkb:"K(+) channel subunit beta-2"(gene name synonym)|uniprotkb:Kv-beta-2(gene name synonym)|uniprotkb:KvB2.1(isoform synonym)|uniprotkb:KCNAB2(gene name)|psi-mi:KCNAB2(display_short)|uniprotkb:KCNA2B(gene name synonym)|uniprotkb:KCNK2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896812|imex:IM-26494-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 ensembl:ENST00000164247(transcript)|ensembl:ENST00000378092(transcript)|ensembl:ENST00000378097(transcript)|ensembl:ENST00000428161(transcript)|ensembl:ENST00000671676(transcript)|ensembl:ENSG00000069424(gene)|intact:EBI-948729(isoform-parent) - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:xH22lEz6vYy0yIz7gNUS91SkeMs9606 rigid:vVn6OfEW5UE1Gb8DNRqcgyU6AiI false his tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:O43781 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-2602828|uniprotkb:Q7Z752|uniprotkb:Q9HBY6|uniprotkb:Q9HBY7|uniprotkb:D3DT79|ensembl:ENSP00000356076 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:dyrk3_human(display_long)|uniprotkb:Regulatory erythroid kinase(gene name synonym)|uniprotkb:DYRK3(gene name)|psi-mi:DYRK3(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896820|imex:IM-26494-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 refseq:NP_001004023.1|refseq:NP_003573.2|ensembl:ENSG00000143479(gene)|ensembl:ENST00000367109(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0051301"(cell division)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1903008"(organelle disassembly)|go:"GO:1903432"(regulation of TORC1 signaling)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042521|rcsb pdb:5Y86|refseq:XP_005273372.1 - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:cW2GsEMjkZZIcq3e2YDKGkEYHkg9606 rigid:gkHQ3KgPFmJZfMKulCg6fgcPDCE false his tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q7KZI7-14 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-26664926|ensembl:ENSP00000423974 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:q7kzi7-14(display_long)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896828|imex:IM-26494-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 ensembl:ENSG00000072518(gene)|ensembl:ENST00000509502(transcript)|intact:EBI-516560(isoform-parent) - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:l40ZZv7fU8zH87dwxHLjiwOvUE09606 rigid:vKgDLVP4TP4oal81ZPgr6+yYP0Q false his tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:P48730-2 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-9087876|ensembl:ENSP00000376146 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:p48730-2(display_long)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896836|imex:IM-26494-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 intact:EBI-751621(isoform-parent)|ensembl:ENSG00000141551(gene)|ensembl:ENST00000392334(transcript)|uniprotkb:P48730-2(isoform-parent) - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:DKYeQTtdg+u5Gm9wscDkiTs7Blg9606 rigid:hYeKDstmga8FdJmvxDWAARozrRY false his tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:O14965 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896844|imex:IM-26494-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606 rigid:TDoytdQdp4neJPVsAmM3/VB+sEc false his tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q8N2I9 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-716112|uniprotkb:Q5VTK8|uniprotkb:Q5VTK9|uniprotkb:Q6ZMN1|uniprotkb:Q8N2J8|uniprotkb:Q8N3I6|uniprotkb:Q96HN6|uniprotkb:Q96I44|uniprotkb:Q9BSA3|uniprotkb:Q9H7H6|uniprotkb:D3DPS8|ensembl:ENSP00000362221|ensembl:ENSP00000362224 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:stk40_human(display_long)|uniprotkb:SGK495(gene name synonym)|uniprotkb:SINK-homologous serine/threonine-protein kinase(gene name synonym)|uniprotkb:Sugen kinase 495(gene name synonym)|uniprotkb:STK40(gene name)|psi-mi:STK40(display_short)|uniprotkb:SHIK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896852|imex:IM-26494-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 refseq:NP_001269475.1|refseq:NP_001269476.1|refseq:NP_114406.1|ensembl:ENSG00000196182(gene)|ensembl:ENST00000373129(transcript)|ensembl:ENST00000373132(transcript)|go:"GO:0003016"(respiratory system process)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0048286"(lung alveolus development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024104|interpro:IPR024236|rcsb pdb:5L2Q|go:"GO:0106310"(protein serine kinase activity) - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:f2777mqQy9IwYGE/+Y7wSNcxhGs9606 rigid:QCaFlpP8F5qbHtU5dhW/MSYhFQw false his tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:P53350 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896860|imex:IM-26494-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:fBOK366hV6mDprx9IWhz43gPcJE9606 rigid:L4ijjksnX+ZK1PyQrZp4YxPwnxw false his tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:P49674 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896872|imex:IM-26494-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320 - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:evdzz03ba4MFWavN9xRae/Wxwio9606 rigid:hwh77MFecjLwZcE6qp7WC+ls0iQ false his tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q62000 uniprotkb:Q9NQU5 intact:EBI-8345812|intact:MINT-4101955|ensembl:ENSMUSP00000021822 intact:EBI-1053685|ensembl:ENSP00000260404|ensembl:ENSP00000401153|ensembl:ENSP00000406873|ensembl:ENSP00000439597|ensembl:ENSP00000453858|ensembl:ENSP00000456785|uniprotkb:A8K2G2|uniprotkb:B3KYB0|uniprotkb:G5E9R2 psi-mi:mime_mouse(display_long)|uniprotkb:Ogn(gene name)|psi-mi:Ogn(display_short)|uniprotkb:Og(gene name synonym)|uniprotkb:Osteoglycin(gene name synonym) psi-mi:pak6_human(display_long)|uniprotkb:p21-activated kinase 6(gene name synonym)|uniprotkb:PAK-5(gene name synonym)|uniprotkb:PAK6(gene name)|psi-mi:PAK6(display_short)|uniprotkb:PAK5(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896880|imex:IM-26494-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032786.1|ensembl:ENSMUSG00000021390(gene)|ensembl:ENSMUST00000021822(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0008083"(growth factor activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027211|interpro:IPR032675|interpro:IPR043547|mint:Q62000|reactome:R-MMU-2022854|reactome:R-MMU-2022857 go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSG00000137843(gene)|ensembl:ENST00000260404(transcript)|ensembl:ENST00000441369(transcript)|ensembl:ENST00000453867(transcript)|ensembl:ENST00000542403(transcript)|ensembl:ENST00000558658(transcript)|ensembl:ENST00000560346(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001263646.1|refseq:NP_001122100.1|refseq:NP_001122101.1|refseq:NP_064553.1|refseq:NP_001263647.1|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0030054"(cell junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140058"(neuron projection arborization)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035066|interpro:IPR036936|rcsb pdb:2C30|rcsb pdb:2ODB|rcsb pdb:4KS7|rcsb pdb:4KS8|rcsb pdb:6QDR|rcsb pdb:6QDS|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013424 - function:Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2|comment:mint - figure legend:Table 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/03/25 rogid:efQRc1wrorUxL8gFP4w8Recr3U410090 rogid:sLf1m1moEJrh+5QFw4V8UgWgxOQ9606 rigid:ZGG07waLikApnaESLEvhhPbP8h0 false his tag:c-c his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O88632 intact:EBI-20725289 intact:EBI-26896611|ensembl:ENSMUSP00000141865|uniprotkb:E9QNC5|uniprotkb:O88633 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:sem3f_mouse(display_long)|uniprotkb:Semaphorin IV(gene name synonym)|uniprotkb:Sema3f(gene name)|psi-mi:Sema3f(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903012|imex:IM-26494-540 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000034684(gene)|ensembl:ENSMUST00000192727(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021675"(nerve development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0036486"(ventral trunk neural crest cell migration)|go:"GO:0040011"(locomotion)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0097490"(sympathetic neuron projection extension)|go:"GO:0097491"(sympathetic neuron projection guidance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1902285"(semaphorin-plexin signaling pathway involved in neuron projection guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001298080.1|refseq:NP_035479.2|refseq:XP_006511739.1|refseq:XP_017168717.1 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:JIfOdCDyp8+wLXEdM/7MTgasRPc10090 - false biotin tag:?-?|tag:?-? sufficient binding region:19-775|mutation:583-583,586-586 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O15041 intact:EBI-20725289 intact:EBI-7283693|uniprotkb:Q75M97|uniprotkb:B4E1P1|uniprotkb:Q75M94|intact:MINT-4507944|ensembl:ENSP00000496491 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:sem3e_human(display_long)|uniprotkb:SEMA3E(gene name)|psi-mi:SEMA3E(display_short)|uniprotkb:KIAA0331(gene name synonym)|uniprotkb:SEMAH(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903028|imex:IM-26494-480 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_036563.1|refseq:NP_001171600.1|ensembl:ENSG00000170381(gene)|ensembl:ENST00000643230(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050808"(synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015513(Semaphorin 3E)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|mint:O15041|reactome:R-HSA-416700 - - comment:mint figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:m6pJKIlr+wF5rd6krKT5Q1MnE6s9606 - false biotin tag:?-?|tag:?-? sufficient binding region:25-775|his tag:n-n|mutation:557-557,560-560 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q16288-3 intact:EBI-20725289 intact:EBI-26563736|ensembl:ENSP00000377990 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q16288-3(display_long)|uniprotkb:GP145-TrkC(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 3(gene name synonym)|uniprotkb:TrkC tyrosine kinase(gene name synonym)|uniprotkb:C(isoform synonym)|uniprotkb:NTRK3(gene name)|psi-mi:NTRK3(display_short)|uniprotkb:TRKC(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903058|imex:IM-26494-542 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000140538(gene)|ensembl:ENST00000394480(transcript)|intact:EBI-3936704(isoform-parent) - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:cUiMWnb8bg+AgxbX4bmtAEW2qNU9606 - false biotin tag:?-?|tag:?-? fc-igg1:c-c|sufficient binding region:32-428|L-histidine residue:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P08138 intact:EBI-20725289 intact:EBI-1387782|uniprotkb:B2R961|uniprotkb:B4E096|ensembl:ENSP00000172229 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:tnr16_human(display_long)|uniprotkb:NGFR(gene name)|psi-mi:NGFR(display_short)|uniprotkb:TNFRSF16(gene name synonym)|uniprotkb:Low-affinity nerve growth factor receptor(gene name synonym)|uniprotkb:Gp80-LNGFR(gene name synonym)|uniprotkb:p75 ICD(gene name synonym)|uniprotkb:Low affinity neurotrophin receptor p75NTR(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903072|imex:IM-26494-482 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_002498.1|dip:DIP-406N|ensembl:ENSG00000064300(gene)|ensembl:ENST00000172229(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005035"(death receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016048"(detection of temperature stimulus)|go:"GO:0021675"(nerve development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035907"(dorsal aorta development)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042488"(positive regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043121"(neurotrophin binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051799"(negative regulation of hair follicle development)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR011029(DEATH-like)|interpro:IPR022325|interpro:IPR034046|interpro:IPR041448|mint:P08138|rcsb pdb:2N80|rcsb pdb:2N83|rcsb pdb:2N97|rcsb pdb:3EWV|rcsb pdb:5ZGG|reactome:R-HSA-193634|reactome:R-HSA-193648|reactome:R-HSA-193670|reactome:R-HSA-193681|reactome:R-HSA-193692|reactome:R-HSA-205017|reactome:R-HSA-205025|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-209563 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:xoP55XGR3zC9f2ClOxgUWU3xnzk9606 - false biotin tag:?-?|tag:?-? fc-igg1:c-c|sufficient binding region:1-250|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q02297-10 intact:EBI-20725289 intact:EBI-12842334|ensembl:ENSP00000433289 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q02297-10(display_long)|uniprotkb:NRG1(gene name)|psi-mi:NRG1(display_short)|uniprotkb:GGF(gene name synonym)|uniprotkb:HGL(gene name synonym)|uniprotkb:HRGA(gene name synonym)|uniprotkb:NDF(gene name synonym)|uniprotkb:SMDF(gene name synonym)|uniprotkb:SMDF(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903110|imex:IM-26494-484 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-2460704(isoform-parent)|uniprotkb:Q02297-10(isoform-parent)|ensembl:ENSG00000157168(gene)|ensembl:ENST00000520502(transcript) - - isoform-comment:"Potential internal signal sequence at positions 76-100. Variant in position: 46:G->R (in dbSNP:rs3735774). Variant in position: 127:A->P (in dbSNP:rs34822181)." figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:2qIc7ATUbJhc1zh4OiBfWjG9OEw9606 - false biotin tag:?-?|tag:?-? his tag:c-c|sufficient binding region:1-241 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P04626-1 intact:EBI-20725289 intact:EBI-26664896|ensembl:ENSP00000269571 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:p04626-1(display_long)|uniprotkb:Metastatic lymph node gene 19 protein(gene name synonym)|uniprotkb:Proto-oncogene Neu(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)|uniprotkb:Tyrosine kinase-type cell surface receptor HER2(gene name synonym)|uniprotkb:p185erbB2(gene name synonym)|uniprotkb:ERBB2(isoform synonym)|uniprotkb:HER2(isoform synonym)|uniprotkb:ERBB2(gene name)|psi-mi:ERBB2(display_short)|uniprotkb:HER2(gene name synonym)|uniprotkb:MLN19(gene name synonym)|uniprotkb:NEU(gene name synonym)|uniprotkb:NGL(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903142|imex:IM-26494-500 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000141736(gene)|ensembl:ENST00000269571(transcript)|intact:EBI-641062(isoform-parent) - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:6o8GoqTQ64og/aKbzFZZMQ8gRHI9606 - false biotin tag:?-?|tag:?-? his tag:c-c|fc-igg1:c-c|sufficient binding region:23-652 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q15303 intact:EBI-20725289 intact:EBI-80371|ensembl:ENSP00000342235|uniprotkb:Q2M1W1|uniprotkb:Q59EW4|uniprotkb:B7ZLE3|uniprotkb:B7ZLD7|uniprotkb:B7ZLE2 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:erbb4_human(display_long)|uniprotkb:ERBB4(gene name)|psi-mi:ERBB4(display_short)|uniprotkb:HER4(gene name synonym)|uniprotkb:p180erbB4(gene name synonym)|uniprotkb:Proto-oncogene-like protein c-ErbB-4(gene name synonym)|uniprotkb:Tyrosine kinase-type cell surface receptor HER4(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903159|imex:IM-26494-486 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0007416"(synapse assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0007507"(heart development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0007595"(lactation)|go:"GO:0043235"(receptor complex)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072046"(establishment of planar polarity involved in nephron morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR032778|interpro:IPR036941|mint:Q15303|rcsb pdb:2AHX|rcsb pdb:2L2T|rcsb pdb:2LCX|rcsb pdb:2R4B|rcsb pdb:3BBT|rcsb pdb:3BBW|rcsb pdb:3BCE|rcsb pdb:3U2P|rcsb pdb:3U7U|rcsb pdb:3U9U|reactome:R-HSA-1227986|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1250342|reactome:R-HSA-1250347|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-1253288|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8863795|reactome:R-HSA-9018519|reactome:R-HSA-9620244|reactome:R-HSA-9664565|reactome:R-HSA-9665686|ensembl:ENSG00000178568(gene)|ensembl:ENST00000342788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|ensembl:ENSP00000342235|ensembl:ENST00000436443|ensembl:ENSP00000403204|refseq:NP_001036064.1|refseq:NP_005226.1|refseq:XP_005246433.1|refseq:XP_005246434.1|dip:DIP-29650N - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:B6LYhMaoSj5IT6caAnj1n262+H49606 - false biotin tag:?-?|tag:?-? his tag:c-c|fc-igg1:c-c|sufficient binding region:26-649 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q15303 intact:EBI-20725289 intact:EBI-80371|ensembl:ENSP00000342235|uniprotkb:Q2M1W1|uniprotkb:Q59EW4|uniprotkb:B7ZLE3|uniprotkb:B7ZLD7|uniprotkb:B7ZLE2 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:erbb4_human(display_long)|uniprotkb:ERBB4(gene name)|psi-mi:ERBB4(display_short)|uniprotkb:HER4(gene name synonym)|uniprotkb:p180erbB4(gene name synonym)|uniprotkb:Proto-oncogene-like protein c-ErbB-4(gene name synonym)|uniprotkb:Tyrosine kinase-type cell surface receptor HER4(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903195|imex:IM-26494-544 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0007416"(synapse assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0007507"(heart development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0007595"(lactation)|go:"GO:0043235"(receptor complex)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072046"(establishment of planar polarity involved in nephron morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR032778|interpro:IPR036941|mint:Q15303|rcsb pdb:2AHX|rcsb pdb:2L2T|rcsb pdb:2LCX|rcsb pdb:2R4B|rcsb pdb:3BBT|rcsb pdb:3BBW|rcsb pdb:3BCE|rcsb pdb:3U2P|rcsb pdb:3U7U|rcsb pdb:3U9U|reactome:R-HSA-1227986|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1250342|reactome:R-HSA-1250347|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-1253288|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8863795|reactome:R-HSA-9018519|reactome:R-HSA-9620244|reactome:R-HSA-9664565|reactome:R-HSA-9665686|ensembl:ENSG00000178568(gene)|ensembl:ENST00000342788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|ensembl:ENSP00000342235|ensembl:ENST00000436443|ensembl:ENSP00000403204|refseq:NP_001036064.1|refseq:NP_005226.1|refseq:XP_005246433.1|refseq:XP_005246434.1|dip:DIP-29650N - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:B6LYhMaoSj5IT6caAnj1n262+H49606 - false biotin tag:?-?|tag:?-? sufficient binding region:26-649 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O55005 intact:EBI-20725289 intact:EBI-3505237 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:robo1_rat(display_long)|uniprotkb:Robo1(gene name)|psi-mi:Robo1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903212|imex:IM-26494-488 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - rgd:61941|refseq:NP_071524.1|go:"GO:0001822"(kidney development)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021510"(spinal cord development)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030673"(axolemma)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032986|interpro:IPR036116|interpro:IPR036179|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|dip:DIP-48941N - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:FZnGpdSe5bamCw6zwkkmzOI6d1s10116 - false biotin tag:?-?|tag:?-? fc-igg1:c-c|sufficient binding region:19-560 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P52793 intact:EBI-20725289 intact:EBI-5241529|uniprotkb:P97331|ensembl:ENSMUSP00000029566 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:efna1_mouse(display_long)|uniprotkb:Efna1(gene name)|psi-mi:Efna1(display_short)|uniprotkb:Epgl1(gene name synonym)|uniprotkb:Epl1(gene name synonym)|uniprotkb:Lerk1(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 1(gene name synonym)|uniprotkb:Immediate early response protein B61(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903225|imex:IM-26494-520 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_034237.3|ensembl:ENSMUSG00000027954(gene)|ensembl:ENSMUST00000029566(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003199"(endocardial cushion to mesenchymal transition involved in heart valve formation)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0014028"(notochord formation)|go:"GO:0016477"(cell migration)|go:"GO:0030182"(neuron differentiation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043535"(regulation of blood vessel endothelial cell migration)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034252|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:TMdL2OCslW4zUNIv7p+p0e/+9MM10090 - false biotin tag:?-?|tag:?-? his tag:c-c|fc-igg1:c-c|sufficient binding region:19-182 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P52801 intact:EBI-20725289 intact:EBI-26903239|ensembl:ENSMUSP00000003154 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:efna2_mouse(display_long)|uniprotkb:CEK7-ligand(gene name synonym)|uniprotkb:ELF-1(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 6(gene name synonym)|uniprotkb:Efna2(gene name)|psi-mi:Efna2(display_short)|uniprotkb:Elf1(gene name synonym)|uniprotkb:Epl6(gene name synonym)|uniprotkb:Eplg6(gene name synonym)|uniprotkb:Lerk6(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903269|imex:IM-26494-502 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000003070(gene)|ensembl:ENSMUST00000003154(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0043204"(perikaryon)|go:"GO:0046849"(bone remodeling)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034252|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665|refseq:NP_031935.3 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:y6yRua736GefFQaJvkUA7Z3gqn810090 - false biotin tag:?-?|tag:?-? his tag:c-c|fc-igg1:c-c|sufficient binding region:1-184 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P52797 intact:EBI-20725289 intact:EBI-722730|uniprotkb:Q0VGC9|uniprotkb:Q5SR70|uniprotkb:D3DV85|uniprotkb:B7ZAD3|intact:EBI-28970463|ensembl:ENSP00000357393 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:efna3_human(display_long)|uniprotkb:EPH-related receptor tyrosine kinase ligand 3(gene name synonym)|uniprotkb:EHK1 ligand(gene name synonym)|uniprotkb:EFL-2(gene name synonym)|uniprotkb:EFNA3(gene name)|psi-mi:EFNA3(display_short)|uniprotkb:EFL2(gene name synonym)|uniprotkb:EPLG3(gene name synonym)|uniprotkb:LERK3(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903283|imex:IM-26494-504 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_004943.1|ensembl:ENSP00000357393|ensembl:ENSG00000143590(gene)|ensembl:ENST00000368408(transcript)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007411"(axon guidance)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034252|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:KgSgyIbTdEtbAMrmvPInOaoK3vY9606 - false biotin tag:?-?|tag:?-? his tag:c-c|fc-igg1:c-c|sufficient binding region:1-209 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O08542 intact:EBI-20725289 intact:EBI-8603023|ensembl:ENSMUSP00000029674|uniprotkb:O55218|intact:MINT-7013357 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:efna4_mouse(display_long)|uniprotkb:Efna4(gene name)|psi-mi:Efna4(display_short)|uniprotkb:Epl4(gene name synonym)|uniprotkb:Eplg4(gene name synonym)|uniprotkb:Lerk4(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 4(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903297|imex:IM-26494-522 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000028040(gene)|ensembl:ENSMUST00000029674(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0048013"(ephrin receptor signaling pathway)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034252|mint:O08542|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665|go:"GO:0046875"(ephrin receptor binding)|refseq:NP_031936.2 - - comment:mint figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:PGa9Y9VBL+RYxOoxL9pRGl2oCnI10090 - false biotin tag:?-?|tag:?-? fc-igg1:c-c|sufficient binding region:1-176 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P52803 intact:EBI-20725289 intact:EBI-1753674|ensembl:ENSP00000328777 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:efna5_human(display_long)|uniprotkb:EFNA5(gene name)|psi-mi:EFNA5(display_short)|uniprotkb:EPLG7(gene name synonym)|uniprotkb:LERK7(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 7(gene name synonym)|uniprotkb:AL-1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903309|imex:IM-26494-524 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001953.1|dip:DIP-48296N|ensembl:ENSG00000184349(gene)|ensembl:ENST00000333274(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005169"(neurotrophin TRKB receptor binding)|go:"GO:0005170"(neurotrophin TRKC receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030297"(transmembrane receptor protein tyrosine kinase activator activity)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034252|rcsb pdb:2X11|rcsb pdb:3MX0|rcsb pdb:4BK5|rcsb pdb:4BKA|rcsb pdb:4L0P|rcsb pdb:4M4R|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:llcBvFrSFaqGGFHXs0ipOgtzAVk9606 - false biotin tag:?-?|tag:?-? fc-igg1:c-c|his tag:c-c|sufficient binding region:1-203 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9HCK4 intact:EBI-20725289 intact:EBI-399800|ensembl:ENSP00000417164|uniprotkb:O43608|uniprotkb:Q19AB4|uniprotkb:Q19AB5|intact:EBI-28972899 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:robo2_human(display_long)|uniprotkb:ROBO2(gene name)|psi-mi:ROBO2(display_short)|uniprotkb:KIAA1568(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903323|imex:IM-26494-506 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000185008(gene)|ensembl:ENST00000461745(transcript)|go:"GO:0001656"(metanephros development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0021510"(spinal cord development)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0030673"(axolemma)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035904"(aorta development)|go:"GO:0042802"(identical protein binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050925"(negative regulation of negative chemotaxis)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1UEM|rcsb pdb:1UJT|rcsb pdb:2EDJ|rcsb pdb:5NOI|rcsb pdb:6I9S|rcsb pdb:6IAA|reactome:R-HSA-376176|reactome:R-HSA-428542|reactome:R-HSA-8985801|reactome:R-HSA-9010553|reactome:R-HSA-9010642|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0008046"(axon guidance receptor activity)|refseq:NP_002933.1|ensembl:ENSP00000417164|ensembl:ENST00000487694|ensembl:ENSP00000417335|refseq:NP_001122401.1|refseq:NP_001276968.1|refseq:NP_001276969.1|refseq:NP_001276994.1 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:AYfQ3Fza8Oo8wQ7Mzhqxm2kW3rs9606 - false biotin tag:?-?|tag:?-? fc-igg1:c-c|sufficient binding region:1-312 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P52795 intact:EBI-20725289 intact:EBI-8107507|intact:MINT-1793539|ensembl:ENSMUSP00000050716 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:efnb1_mouse(display_long)|uniprotkb:Efnb1(gene name)|psi-mi:Efnb1(display_short)|uniprotkb:Epl2(gene name synonym)|uniprotkb:Eplg2(gene name synonym)|uniprotkb:Lerk2(gene name synonym)|uniprotkb:Stra1(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 2(gene name synonym)|uniprotkb:CEK5 receptor ligand(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 1 protein(gene name synonym)|uniprotkb:ELK ligand(gene name synonym)|uniprotkb:EFL-3(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903335|imex:IM-26494-490 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_034240.1|dip:DIP-29206N|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52795|rcsb pdb:6P7S|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|go:"GO:0099054"(presynapse assembly)|ensembl:ENSMUSG00000031217(gene)|ensembl:ENSMUST00000052839(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031295"(T cell costimulation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0098978"(glutamatergic synapse) - - function:Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons|comment:mint figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:Js3TO3daJCJdawFl8NX7HMgbpkM10090 - false biotin tag:?-?|tag:?-? his tag:c-c|sufficient binding region:30-229|fc-igg1:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P52800 intact:EBI-20725289 intact:EBI-1032676|ensembl:ENSMUSP00000001319 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:efnb2_mouse(display_long)|uniprotkb:Elf2(gene name synonym)|uniprotkb:Epl5(gene name synonym)|uniprotkb:Eplg5(gene name synonym)|uniprotkb:Htkl(gene name synonym)|uniprotkb:Lerk5(gene name synonym)|uniprotkb:Efnb2(gene name)|psi-mi:Efnb2(display_short)|uniprotkb:EPH-related receptor tyrosine kinase ligand 5(gene name synonym)|uniprotkb:ELF-2(gene name synonym)|uniprotkb:HTK ligand(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903367|imex:IM-26494-508 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_034241.2|ensembl:ENSMUSG00000001300(gene)|ensembl:ENSMUST00000001319(transcript)|go:"GO:0001945"(lymph vessel development)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|interpro:IPR034255|mint:P52800|rcsb pdb:1IKO|rcsb pdb:1KGY|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|dip:DIP-29208N - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:P051BaTxVceRTs9h3ugIgtq/EGo10090 - false biotin tag:?-?|tag:?-? sufficient binding region:29-229|fc-igg1:c-c|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q15768 intact:EBI-20725289 intact:EBI-3908475|uniprotkb:Q92875|uniprotkb:Q8TBH7|uniprotkb:D3DTQ6|uniprotkb:B2RBW2|uniprotkb:O00680|ensembl:ENSP00000226091 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:efnb3_human(display_long)|uniprotkb:EFNB3(gene name)|psi-mi:EFNB3(display_short)|uniprotkb:EPLG8(gene name synonym)|uniprotkb:LERK8(gene name synonym)|uniprotkb:EPH-related receptor transmembrane ligand ELK-L3(gene name synonym)|uniprotkb:EPH-related receptor tyrosine kinase ligand 8(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903394|imex:IM-26494-546 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001397.1|ensembl:ENSG00000108947(gene)|ensembl:ENST00000226091(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007628"(adult walking behavior)|go:"GO:0016198"(axon choice point recognition)|go:"GO:0031295"(T cell costimulation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|interpro:IPR001799(Ephrin)|interpro:IPR008972(Cupredoxin)|interpro:IPR019765|interpro:IPR031328|mint:Q15768|rcsb pdb:4BKF|reactome:R-HSA-2682334|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|dip:DIP-59196N - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:SCKHF/6JfjSaED+FsgWMp2o4aDI9606 - false biotin tag:?-?|tag:?-? fc-igg1:c-c|sufficient binding region:1-224 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P21709 intact:EBI-20725289 intact:EBI-968453|ensembl:ENSP00000275815|ensembl:ENSP00000494931|uniprotkb:B5A966|uniprotkb:B5A967|uniprotkb:Q15405|uniprotkb:A1L3V3 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:epha1_human(display_long)|uniprotkb:EPHA1(gene name)|psi-mi:EPHA1(display_short)|uniprotkb:EPH(gene name synonym)|uniprotkb:EPHT(gene name synonym)|uniprotkb:EPHT1(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH(gene name synonym)|uniprotkb:EPH tyrosine kinase(gene name synonym)|uniprotkb:EPH tyrosine kinase 1(gene name synonym)|uniprotkb:Erythropoietin-producing hepatoma receptor(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903407|imex:IM-26494-526 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000146904(gene)|ensembl:ENSG00000284816(gene)|ensembl:ENST00000275815(transcript)|ensembl:ENST00000645847(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034251|interpro:IPR036116|mint:P21709|rcsb pdb:2K1K|rcsb pdb:2K1L|rcsb pdb:3HIL|rcsb pdb:3KKA|reactome:R-HSA-2682334|reactome:R-HSA-2892247|reactome:R-HSA-3928663|reactome:R-HSA-3928665|refseq:NP_005223.4|dip:DIP-34886N - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:TB6kRxNntZnW6eicjTb94922jDM9606 - false biotin tag:?-?|tag:?-? fc-igg1:c-c|sufficient binding region:1-547 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q8BRB1 intact:EBI-20725289 intact:EBI-26903419|ensembl:ENSMUSP00000066554 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q8brb1_mouse(display_long)|uniprotkb:Epha3(gene name)|psi-mi:Epha3(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903462|imex:IM-26494-548 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000052504(gene)|ensembl:ENSMUST00000064405(transcript)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034266|interpro:IPR036116|refseq:NP_034270.1 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:APl536b2Rxa2YmVXl9ClF2K+aoI10090 - false biotin tag:?-?|tag:?-? his tag:c-c|fc-igg1:c-c|mutation:323-323,476-476|sufficient binding region:1-541 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q03137 intact:EBI-20725289 intact:EBI-1539152|uniprotkb:Q80VZ2|ensembl:ENSMUSP00000027451|ensembl:ENSMUSP00000139640|ensembl:ENSMUSP00000140954 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:epha4_mouse(display_long)|uniprotkb:Tyrosine-protein kinase receptor SEK-1(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor MPK-3(gene name synonym)|uniprotkb:Epha4(gene name)|psi-mi:Epha4(display_short)|uniprotkb:Sek(gene name synonym)|uniprotkb:Sek1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26903479|imex:IM-26494-510 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_031962.2|dip:DIP-1019N|ensembl:ENSMUST00000027451(transcript)|ensembl:ENSMUST00000188797(transcript)|ensembl:ENSMUST00000188952(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008347"(glial cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016301"(kinase activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042731"(PH domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043235"(receptor complex)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0048710"(regulation of astrocyte differentiation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0072178"(nephric duct morphogenesis)|go:"GO:0090102"(cochlea development)|go:"GO:0097155"(fasciculation of sensory neuron axon)|go:"GO:0097156"(fasciculation of motor neuron axon)|go:"GO:0097161"(DH domain binding)|go:"GO:0097485"(neuron projection guidance)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098883"(synapse pruning)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106030"(neuron projection fasciculation)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903051"(negative regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905244"(regulation of modification of synaptic structure)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|ensembl:ENSMUSG00000026235(gene)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR030602|interpro:IPR034270|interpro:IPR036116|mint:Q03137|rcsb pdb:1B0X|rcsb pdb:2HEL|rcsb pdb:2I8J|rcsb pdb:2XYU|rcsb pdb:2Y6M|rcsb pdb:2Y6O|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/07 - rogid:cDRUcRD/LB5owMEI7vdfcaD90uE10090 - false biotin tag:?-?|tag:?-? his tag:c-c|fc-igg1:c-c|sufficient binding region:1-547 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q62413 intact:EBI-20725289 intact:EBI-26904580|uniprotkb:B9EIV2|uniprotkb:Q8CCN2 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:epha6_mouse(display_long)|uniprotkb:Epha6(gene name)|psi-mi:Epha6(display_short)|uniprotkb:Ehk-2(gene name synonym)|uniprotkb:Ehk2(gene name synonym)|uniprotkb:EPH homology kinase 2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904623|imex:IM-26494-512 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|rcsb pdb:5ZRY|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665|interpro:IPR042746|interpro:IPR027936|interpro:IPR034280|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR036116|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR020635|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site) - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:I5nEbwDRRrd5QyEUsgdWVICAfd010090 - false tag:?-?|biotin tag:?-? his tag:c-c|fc-igg1:c-c|sufficient binding region:1-546 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q61772-3 intact:EBI-20725289 intact:EBI-26904637 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:q61772-3(display_long)|uniprotkb:Developmental kinase 1(gene name synonym)|uniprotkb:EPH homology kinase 3(gene name synonym)|uniprotkb:Embryonic brain kinase(gene name synonym)|uniprotkb:Epha7(gene name)|psi-mi:Epha7(display_short)|uniprotkb:Ebk(gene name synonym)|uniprotkb:Ehk3(gene name synonym)|uniprotkb:Mdk1(gene name synonym)|uniprotkb:MDK1-2(isoform synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904647|imex:IM-26494-528 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - intact:EBI-26947447(isoform-parent) - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:6tFhkr2HV/MUf5beA7dODlq7g0Q10090 - false tag:?-?|biotin tag:?-? his tag:c-c|sufficient binding region:1-549|fc-igg1:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O09127 intact:EBI-20725289 intact:EBI-7087039|ensembl:ENSMUSP00000030420|uniprotkb:A3KG07|intact:MINT-5312751 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:epha8_mouse(display_long)|uniprotkb:Epha8(gene name)|psi-mi:Epha8(display_short)|uniprotkb:Eek(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EEK(gene name synonym)|uniprotkb:EPH- and ELK-related kinase(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904661|imex:IM-26494-492 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000028661(gene)|ensembl:ENSMUST00000030420(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016322"(neuron remodeling)|go:"GO:0019838"(growth factor binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR020691|interpro:IPR027936|interpro:IPR034287|interpro:IPR036116|reactome:R-MMU-2682334|reactome:R-MMU-3928663|reactome:R-MMU-3928665|refseq:NP_031965.2 - - comment:mint|function:Receptor for members of the ephrin-A family. Interacts at least with ephrin-A2, -A3, and -A5 figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:rC7G83J70zQqwU9rmWf4Tp1YOzA10090 - false tag:?-?|biotin tag:?-? fc-igg1:c-c|his tag:c-c|sufficient binding region:1-540 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P09759 intact:EBI-20725289 intact:EBI-26904675|ensembl:ENSRNOP00000010634 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ephb1_rat(display_long)|uniprotkb:ELK(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EPH-2(gene name synonym)|uniprotkb:Ephb1(gene name)|psi-mi:Ephb1(display_short)|uniprotkb:Elk(gene name synonym)|uniprotkb:Epth2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904755|imex:IM-26494-514 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - dip:DIP-138N|rgd:2556|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902723"(negative regulation of skeletal muscle satellite cell proliferation)|go:"GO:1902725"(negative regulation of satellite cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034231|interpro:IPR036116|interpro:IPR042819|reactome:R-RNO-2682334|reactome:R-RNO-3928662|reactome:R-RNO-3928664|reactome:R-RNO-3928665|ensembl:ENSRNOG00000007865(gene)|ensembl:ENSRNOT00000010634(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0014719"(skeletal muscle satellite cell activation)|go:"GO:0016020"(membrane)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022008"(neurogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|refseq:NP_001097998.1|refseq:XP_017450939.1 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:bDeHs+jfMmhv4Q19bL4F0OT6lPc10116 - false tag:?-?|biotin tag:?-? fc-igg1:c-c|sufficient binding region:18-538 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P54754 intact:EBI-20725289 intact:EBI-26904795|ensembl:ENSMUSP00000006112|uniprotkb:Q62214|uniprotkb:Q91YS9 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ephb3_mouse(display_long)|uniprotkb:Ephb3(gene name)|psi-mi:Ephb3(display_short)|uniprotkb:Etk2(gene name synonym)|uniprotkb:Mdk5(gene name synonym)|uniprotkb:Sek4(gene name synonym)|uniprotkb:Developmental kinase 5(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor SEK-4(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904862|imex:IM-26494-530 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000005958(gene)|ensembl:ENSMUST00000006112(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001655"(urogenital system development)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005003"(ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008046"(axon guidance receptor activity)|go:"GO:0016477"(cell migration)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022038"(corpus callosum development)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030425"(dendrite)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043235"(receptor complex)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034245|interpro:IPR036116|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060997"(dendritic spine morphogenesis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|refseq:NP_034273.1 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:Et+OYdDtNIx5WiMNDLq8v1GBtbs10090 - false tag:?-?|biotin tag:?-? fc-igg1:c-c|sufficient binding region:30-537|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P54761 intact:EBI-20725289 intact:EBI-26904876|ensembl:ENSMUSP00000051622|ensembl:ENSMUSP00000115731|ensembl:ENSMUSP00000130275|uniprotkb:Q60627|uniprotkb:Q99MR2 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:ephb4_mouse(display_long)|uniprotkb:Ephb4(gene name)|psi-mi:Ephb4(display_short)|uniprotkb:Htk(gene name synonym)|uniprotkb:Mdk2(gene name synonym)|uniprotkb:Myk1(gene name synonym)|uniprotkb:Developmental kinase 2(gene name synonym)|uniprotkb:Hepatoma transmembrane kinase(gene name synonym)|uniprotkb:Tyrosine kinase MYK-1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904937|imex:IM-26494-516 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000029710(gene)|ensembl:ENSMUST00000061244(transcript)|ensembl:ENSMUST00000144296(transcript)|ensembl:ENSMUST00000166239(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005003"(ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000525"(positive regulation of T cell costimulation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011641(GCC2 and GCC3)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034290|interpro:IPR036116|interpro:IPR037636|reactome:R-MMU-2682334|reactome:R-MMU-3928662|reactome:R-MMU-3928664|reactome:R-MMU-3928665|refseq:NP_034274.4 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:qDlaqeS5HJFXBbZUkFh+44sekQQ10090 - false tag:?-?|biotin tag:?-? his tag:c-c|fc-igg1:c-c|sufficient binding region:16-539 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q14563 intact:EBI-20725289 intact:EBI-26610586|ensembl:ENSP00000265362|ensembl:ENSP00000415260 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:sem3a_human(display_long)|uniprotkb:Semaphorin III(gene name synonym)|uniprotkb:SEMA3A(gene name)|psi-mi:SEMA3A(display_short)|uniprotkb:SEMAD(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904951|imex:IM-26494-518 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000075213(gene)|ensembl:ENST00000265362(transcript)|ensembl:ENST00000436949(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021675"(nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021828"(gonadotrophin-releasing hormone neuronal migration to the hypothalamus)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036486"(ventral trunk neural crest cell migration)|go:"GO:0038191"(neuropilin binding)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0048880"(sensory system development)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0060385"(axonogenesis involved in innervation)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061551"(trigeminal ganglion development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0097490"(sympathetic neuron projection extension)|go:"GO:0097491"(sympathetic neuron projection guidance)|go:"GO:0150020"(basal dendrite arborization)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1902285"(semaphorin-plexin signaling pathway involved in neuron projection guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1903045"(neural crest cell migration involved in sympathetic nervous system development)|go:"GO:1903375"(facioacoustic ganglion development)|go:"GO:2000020"(positive regulation of male gonad development)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|interpro:IPR042820|mint:Q14563|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|dip:DIP-5744N|refseq:NP_006071.1|refseq:XP_005250167.1|refseq:XP_005250168.1|refseq:XP_006715902.1|refseq:XP_011514036.1|refseq:XP_016867162.1 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:LrzZi1ccIRowKEYyzaG9pQco39E9606 - false tag:?-?|biotin tag:?-? fc-igg1:c-c|his tag:n-n|mutation:552-552,555-555|sufficient binding region:26-771 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9H3S1 intact:EBI-20725289 intact:EBI-3924922|uniprotkb:B3KR76|uniprotkb:Q5TCJ6|uniprotkb:B2RDH8|uniprotkb:Q8WUA9|uniprotkb:Q5TCI5|ensembl:ENSP00000347117|ensembl:ENSP00000357265|ensembl:ENSP00000357268 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:sem4a_human(display_long)|uniprotkb:SEMA4A(gene name)|psi-mi:SEMA4A(display_short)|uniprotkb:SEMAB(gene name synonym)|uniprotkb:SEMB(gene name synonym)|uniprotkb:Semaphorin-B(gene name synonym)|uniprotkb:UNQ783/PRO1317(orf name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904968|imex:IM-26494-494 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_011508174.1|refseq:XP_011508175.1|refseq:NP_001180229.1|refseq:NP_001180230.1|refseq:NP_001180231.1|refseq:NP_071762.2|ensembl:ENSG00000196189(gene)|ensembl:ENST00000355014(transcript)|ensembl:ENST00000368282(transcript)|ensembl:ENST00000368285(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:1904891"(positive regulation of excitatory synapse assembly)|go:"GO:1905704"(positive regulation of inhibitory synapse assembly)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|mint:Q9H3S1|reactome:R-HSA-416700|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|refseq:XP_016857545.1 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:mET6IfHJaauZpacRiDhcsm/uDTw9606 - false tag:?-?|biotin tag:?-? sufficient binding region:32-683|fc-igg1:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9H2E6 intact:EBI-20725289 intact:EBI-311295|uniprotkb:Q9P2H9|ensembl:ENSP00000345512|ensembl:ENSP00000424388 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:sem6a_human(display_long)|uniprotkb:SEMA6A(gene name)|psi-mi:SEMA6A(display_short)|uniprotkb:KIAA1368(gene name synonym)|uniprotkb:SEMAQ(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904980|imex:IM-26494-532 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_065847.1|refseq:NP_001287709.1|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0106089"(negative regulation of cell adhesion involved in sprouting angiogenesis)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|rcsb pdb:6WTS|reactome:R-HSA-416700|ensembl:ENSG00000092421(gene)|ensembl:ENST00000343348(transcript)|ensembl:ENST00000510263(transcript)|go:"GO:0001755"(neural crest cell migration) - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:4DFr78PrSaGvR6om5lXlNBZPYt89606 - false tag:?-?|biotin tag:?-? fc-igg1:c-c|sufficient binding region:1-649 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9H2E6 intact:EBI-20725289 intact:EBI-311295|uniprotkb:Q9P2H9|ensembl:ENSP00000345512|ensembl:ENSP00000424388 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:sem6a_human(display_long)|uniprotkb:SEMA6A(gene name)|psi-mi:SEMA6A(display_short)|uniprotkb:KIAA1368(gene name synonym)|uniprotkb:SEMAQ(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26904992|imex:IM-26494-534 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_065847.1|refseq:NP_001287709.1|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0106089"(negative regulation of cell adhesion involved in sprouting angiogenesis)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|rcsb pdb:6WTS|reactome:R-HSA-416700|ensembl:ENSG00000092421(gene)|ensembl:ENST00000343348(transcript)|ensembl:ENST00000510263(transcript)|go:"GO:0001755"(neural crest cell migration) - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:4DFr78PrSaGvR6om5lXlNBZPYt89606 - false tag:?-?|biotin tag:?-? sufficient binding region:1-649 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9H3T3 intact:EBI-20725289 intact:EBI-25432706|ensembl:ENSP00000467290|ensembl:ENSP00000503414|uniprotkb:A5PKU4|uniprotkb:F6IB19|uniprotkb:Q9NRK9 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:sem6b_human(display_long)|uniprotkb:Semaphorin-Z(gene name synonym)|uniprotkb:UNQ1907/PRO4353(orf name)|uniprotkb:SEMA6B(gene name)|psi-mi:SEMA6B(display_short)|uniprotkb:SEMAN(gene name synonym)|uniprotkb:SEMAZ(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26905004|imex:IM-26494-550 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000167680(gene)|ensembl:ENST00000586582(transcript)|ensembl:ENST00000676793(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027231|interpro:IPR036352|refseq:NP_115484.2 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:HcJG/zQjP5iQEhU4UWxA+5+1d649606 - false tag:?-?|biotin tag:?-? fc-igg1:c-c|sufficient binding region:26-603 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O09118 intact:EBI-20725289 intact:EBI-1798844|uniprotkb:B1ARR0|uniprotkb:Q60832|uniprotkb:Q9QY50|ensembl:ENSMUSP00000021284|ensembl:ENSMUSP00000104314 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:net1_mouse(display_long)|uniprotkb:Ntn1(gene name)|psi-mi:Ntn1(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26905016|imex:IM-26494-496 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_032770.2|ensembl:ENSMUSG00000020902(gene)|ensembl:ENSMUST00000021284(transcript)|ensembl:ENSMUST00000108674(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007097"(nuclear migration)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030879"(mammary gland development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0061643"(chemorepulsion of axon)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071944"(cell periphery)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|rcsb pdb:4OVE|reactome:R-MMU-373752|reactome:R-MMU-418885 - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:03RX6IHBOrGA1HJPLlszlp+P6i410090 - false tag:?-?|biotin tag:?-? his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q90923 intact:EBI-20725289 intact:EBI-26905028 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:net3_chick(display_long)|uniprotkb:NTN3(gene name)|psi-mi:NTN3(display_short)|uniprotkb:NTN2(gene name synonym)|uniprotkb:Netrin-2(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26905049|imex:IM-26494-498 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016358"(dendrite development)|refseq:NP_001264534.1|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008993(TIMP-like, OB-fold) - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:7KFbmsr7HDx+oUq1afXeb5T2o6k9031 - false tag:?-?|biotin tag:?-? his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:Q9HB63 intact:EBI-20725289 intact:EBI-743459|ensembl:ENSP00000340998|uniprotkb:Q658K9|uniprotkb:Q7L3F1|uniprotkb:Q7L9D6|uniprotkb:Q7Z5B6|uniprotkb:Q9BZP1|uniprotkb:Q9NT44|uniprotkb:Q9P133|uniprotkb:B2RNC2 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:net4_human(display_long)|uniprotkb:Beta-netrin(gene name synonym)|uniprotkb:Hepar-derived netrin-like protein(gene name synonym)|uniprotkb:NTN4(gene name)|psi-mi:NTN4(display_short) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26905059|imex:IM-26494-536 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR018933|ensembl:ENSG00000074527(gene)|ensembl:ENST00000343702(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043237"(laminin-1 binding)|interpro:IPR035811|reactome:R-HSA-3000171|reactome:R-HSA-373752|go:"GO:0043256"(laminin complex)|go:"GO:0060668"(regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001134(Netrin, C-terminal)|refseq:NP_067052.2|refseq:NP_001316629.1|refseq:NP_001316630.1|refseq:NP_001316631.1|dip:DIP-46274N - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:Wiq3R27SFsSneLrCDSpL19glpxE9606 - false tag:?-?|biotin tag:?-? his tag:c-c|sufficient binding region:1-628 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O08722 intact:EBI-20725289 intact:EBI-4404185 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:unc5b_rat(display_long)|uniprotkb:Unc5b(gene name)|psi-mi:Unc5b(display_short)|uniprotkb:Unc5h2(gene name synonym)|uniprotkb:Protein unc-5 homolog 2(gene name synonym)|uniprotkb:Protein unc-5 homolog B(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26905071|imex:IM-26494-538 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - rgd:621756|refseq:NP_071543.1|dip:DIP-60743N|go:"GO:0005042"(netrin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033564"(anterior/posterior axon guidance)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000488(Death)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR000906(ZU5)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011029(DEATH-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033772|interpro:IPR036179|interpro:IPR036383|interpro:IPR037936|interpro:IPR042156|rcsb pdb:3G5B|go:"GO:0045121"(membrane raft) - - - figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/08 - rogid:eMLpHKP8+9+6y69jsrnTolsZdEI10116 - false tag:?-?|biotin tag:?-? fc-igg1:c-c|sufficient binding region:1-373 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" matrixdb:MULT_79_rat intact:EBI-20725289 intact:EBI-26905393 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:pdgfab_rat(display_short)|psi-mi:MULT_79_rat(display_long)|intact:Platelet-derived growth factor AB complex(complex recommended name)|intact:Platelet-derived growth factor AB complex(complex systematic name) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26957372|imex:IM-26494-551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:1302"(stable complex) - go:"GO:1990265"(platelet-derived growth factor complex)|evidence ontology:"ECO:0005544"|complex portal:CPX-1875(inferred-from)|go:"GO:0008083"(growth factor activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|pubmed:11831861(see-also)|pubmed:7679113(see-also)|complex portal:CPX-6591(complex-primary) - - curated-complex:"A- and B-chain of the platelet-derived growth factor (PDGF). Binds to and activates PDGF receptor alpha (PDGFRalpha, P20786) and beta (PDGFRbeta, Q05030) subunits by inducing receptor dimerisation and tyrosine phosphorylation. Is a potent mitogen for cells of mesenchymal origin. Plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Plays an important role in wound healing."|complex-properties:"Anti-parallel heterodimer. Binds to PDGF receptor alpha and beta homo- and heterodimers.. Assembled into disulphide-linked dimers in the endoplasmic reticulum as inactive precursors. Proteolytic processing is necessary for activation and biological function in the exocytic pathway. Predicted Mw: 24.8 kDa"|complex-assembly:Heterodimer figure legend:Table 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/20 - - - false biotin tag:?-?|tag:?-? sufficient binding region:87-196,74-182 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:P53350 intact:EBI-20725289 intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym) psi-mi:"MI:0089"(protein array) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26963279|imex:IM-26494-552 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N - - - figure legend:Table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/08/28 2021/04/26 - rogid:fBOK366hV6mDprx9IWhz43gPcJE9606 - false biotin tag:?-?|tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60924" uniprotkb:O94813 intact:EBI-20725289 intact:EBI-1236865|uniprotkb:O95710|uniprotkb:Q17RU3|uniprotkb:Q9Y5Q7|uniprotkb:B7ZLR5|uniprotkb:A0A0A6YYB8|ensembl:ENSP00000422591 psi-mi:keratan sulfate(display_short)|psi-mi:"CHEBI:60924"(display_long)|intact:keratan sulfates(synonym)|intact:keratosulfate(synonym) psi-mi:slit2_human(display_long)|uniprotkb:SLIT2(gene name)|psi-mi:SLIT2(display_short)|uniprotkb:SLIL3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Conrad et al. (2010) pubmed:20375348|imex:IM-26494 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0917"(matrixdb) intact:EBI-26896694|imex:IM-26494-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:NP_001276064.1|refseq:NP_001276065.1|refseq:NP_004778.1|dip:DIP-38198N|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021972"(corticospinal neuron axon guidance through spinal cord)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0050929"(induction of negative chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051414"(response to cortisol)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071676"(negative regulation of mononuclear cell migration)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|go:"GO:0090027"(negative regulation of monocyte chemotaxis)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|mint:O94813|rcsb pdb:2V70|rcsb pdb:2V9S|rcsb pdb:2V9T|rcsb pdb:2WFH|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-9010553|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|ensembl:ENSG00000145147(gene)|ensembl:ENST00000504154(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002689"(negative regulation of leukocyte chemotaxis)|go:"GO:0003180"(aortic valve morphogenesis) - - - figure legend:Figure 1, Figure 2, Table 8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kon:1.17x10^3 ~0.24(per mole per second)|koff:3.45x10^-7 ~2.37(second -1)|kd:2.0x10^-8 ~15.35(molar) 2018/08/28 2021/03/25 - rogid:25Wc98dEfv1yROTD5pUtyQ+LWN89606 - false biotin tag:?-?|tag:?-? his tag:c-c|sufficient binding region:26-1118 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)