#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-20749408 intact:EBI-20750170 rnacentral:URS00004208C5_9606 ensembl:ENST00000425538.5 psi-mi:hsa-mir-9-5p(display_short)|psi-mi:EBI-20749408(display_long) psi-mi:mrna_myocardin(display_short)|psi-mi:EBI-20750170(display_long) psi-mi:"MI:2285"(miRNA interference luciferase reporter assay) Wang et al. (2010) pubmed:20177053|imex:IM-26516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20764578|imex:IM-26516-1 - - psi-mi:"MI:2274"(regulator) psi-mi:"MI:2275"(regulator target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:2204"(micro rna) psi-mi:"MI:0324"(messenger rna) - refseq:NM_001146312.2(see-also) go:"GO:1903231"(mRNA binding involved in posttranscriptional gene silencing) - - figure legend:Fig 6A, D|causality statement:down-regulates quantity by destabilization|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2018/09/20 2018/09/20 - - - false - luciferase tag:?-?|mutation decreasing interaction:4097-4100 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:1220"(tag visualisation by luciferase assay) ensembl:ENSG00000141052 uniprotkb:Q12968 intact:EBI-20764606 intact:EBI-5278441|uniprotkb:O75211|uniprotkb:Q14516|uniprotkb:Q99840|uniprotkb:Q99841|uniprotkb:Q99842|ensembl:ENSP00000300659 psi-mi:myocardin(display_short)|psi-mi:ENSG00000141052(display_long) psi-mi:nfac3_human(display_long)|uniprotkb:NFATC3(gene name)|psi-mi:NFATC3(display_short)|uniprotkb:NFAT4(gene name synonym)|uniprotkb:NFATx(gene name synonym)|uniprotkb:T-cell transcription factor NFAT4(gene name synonym) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Wang et al. (2010) pubmed:20177053|imex:IM-26516 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20764603|imex:IM-26516-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0250"(gene) psi-mi:"MI:0326"(protein) - refseq:NP_004546.1|refseq:NP_775186.1|refseq:NP_775188.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1902894"(negative regulation of miRNA transcription)|ensembl:ENSG00000072736(gene)|ensembl:ENST00000346183(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR032397|interpro:IPR037059|rcsb pdb:2XRW|rcsb pdb:2XS0|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-5607763 - - - figure legend:Fig3D|agonist:"Isoproterenol (CHEBI:64317); aldosterone (CHEBI:27584)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-cardiomyocytes)|taxid:9606(human cardiomyocytes) - 2018/09/20 2018/09/20 - rogid:YhaCvxbZKhSOtPQqf5dj5XVr8X89606 - false - - - - psi-mi:"MI:0088"(primer specific pcr) psi-mi:"MI:0421"(identification by antibody)