#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q03188 uniprotkb:Q03188 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Trazzi et al. (2009) pubmed:19503796|imex:IM-26679 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20812842|imex:IM-26679-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Fig. 4B, 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2018/10/29 2018/10/29 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:8tuEGk2loIpVl+/ZUVFmplm6qmA false sufficient binding region:638-943|ha tag:n-n sufficient binding region:760-943|flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P49450 uniprotkb:Q03188 intact:EBI-1751979|uniprotkb:D6W544|uniprotkb:Q53T74|uniprotkb:Q9BVW2|ensembl:ENSP00000336868 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:cenpa_human(display_long)|uniprotkb:CENPA(gene name)|psi-mi:CENPA(display_short)|uniprotkb:Centromere autoantigen A(gene name synonym)|uniprotkb:Centromere protein A(gene name synonym) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Trazzi et al. (2009) pubmed:19503796|imex:IM-26679 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20812906|imex:IM-26679-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035891.1|refseq:NP_001800.1|dip:DIP-52297N|ensembl:ENSG00000115163(gene)|ensembl:ENST00000335756(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000939"(inner kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:3AN2|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3R45|rcsb pdb:3WTP|rcsb pdb:5CVD|rcsb pdb:5Z23|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6KDQ|rcsb pdb:6KDS|rcsb pdb:6L49|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6TEM|rcsb pdb:7D20|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2018/10/29 2018/10/29 rogid:p+4MxwgHYHM9fpMXrAec/uZshTA9606 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:VmOoBq+3y0db4Xeh7UE+4gLmYTc false ha tag:n-n sufficient binding region:638-943|flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P49450 uniprotkb:Q03188 intact:EBI-1751979|uniprotkb:D6W544|uniprotkb:Q53T74|uniprotkb:Q9BVW2|ensembl:ENSP00000336868 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:cenpa_human(display_long)|uniprotkb:CENPA(gene name)|psi-mi:CENPA(display_short)|uniprotkb:Centromere autoantigen A(gene name synonym)|uniprotkb:Centromere protein A(gene name synonym) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Trazzi et al. (2009) pubmed:19503796|imex:IM-26679 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20812918|imex:IM-26679-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035891.1|refseq:NP_001800.1|dip:DIP-52297N|ensembl:ENSG00000115163(gene)|ensembl:ENST00000335756(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000939"(inner kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:3AN2|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3R45|rcsb pdb:3WTP|rcsb pdb:5CVD|rcsb pdb:5Z23|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6KDQ|rcsb pdb:6KDS|rcsb pdb:6L49|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6TEM|rcsb pdb:7D20|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Fig. 6C Fig.7|comment:"Again the HA::CENP-A was immunoprecipitated and the IP complexes were analyzed by Western blotting with an anti-FLAG antibody. Results show that the C-terminal domain (aa 638–943) can be efficiently co-immunoprecipitated with CENP-A. Consistent results were obtained when the reciprocal experiment was performed. HA::CENP-C and FLAG::CENP-A constructs were cotransfected into HEK-293 cells, immunoprecipitated with an anti-HA antibody and FLAG-tagged proteins were detected (Figure 6C)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2018/10/29 2018/10/29 rogid:p+4MxwgHYHM9fpMXrAec/uZshTA9606 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:VmOoBq+3y0db4Xeh7UE+4gLmYTc false flag tag:n-n sufficient binding region:638-943|ha tag:n-n|necessary binding region:819-943 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q03188 uniprotkb:Q03188 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Trazzi et al. (2009) pubmed:19503796|imex:IM-26679 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20812865|imex:IM-26679-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/10/29 2018/10/29 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:TsAxRFjTEUcryiq0KV7Xy8h0Tjk false ha tag:n-n|sufficient binding region:760-943 ha tag:n-n|sufficient binding region:760-943 2 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q03188 uniprotkb:Q03188 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Trazzi et al. (2009) pubmed:19503796|imex:IM-26679 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20812872|imex:IM-26679-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/10/29 2018/10/29 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:TsAxRFjTEUcryiq0KV7Xy8h0Tjk false ha tag:n-n|sufficient binding region:638-943 ha tag:n-n|sufficient binding region:638-943 3 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q03188 uniprotkb:Q03188 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Trazzi et al. (2009) pubmed:19503796|imex:IM-26679 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20812879|imex:IM-26679-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/10/29 2018/10/29 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:TsAxRFjTEUcryiq0KV7Xy8h0Tjk false ha tag:n-n|sufficient binding region:638-943 ha tag:n-n|sufficient binding region:638-943 4 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P49450 uniprotkb:Q03188 intact:EBI-1751979|uniprotkb:D6W544|uniprotkb:Q53T74|uniprotkb:Q9BVW2|ensembl:ENSP00000336868 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:cenpa_human(display_long)|uniprotkb:CENPA(gene name)|psi-mi:CENPA(display_short)|uniprotkb:Centromere autoantigen A(gene name synonym)|uniprotkb:Centromere protein A(gene name synonym) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Trazzi et al. (2009) pubmed:19503796|imex:IM-26679 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20812892|imex:IM-26679-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035891.1|refseq:NP_001800.1|dip:DIP-52297N|ensembl:ENSG00000115163(gene)|ensembl:ENST00000335756(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000939"(inner kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:3AN2|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3R45|rcsb pdb:3WTP|rcsb pdb:5CVD|rcsb pdb:5Z23|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6KDQ|rcsb pdb:6KDS|rcsb pdb:6L49|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6TEM|rcsb pdb:7D20|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 go:"GO:0005634"(nucleus) - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2018/10/29 2018/10/29 rogid:p+4MxwgHYHM9fpMXrAec/uZshTA9606 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:VmOoBq+3y0db4Xeh7UE+4gLmYTc false ha tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49450 uniprotkb:Q03188 intact:EBI-1751979|uniprotkb:D6W544|uniprotkb:Q53T74|uniprotkb:Q9BVW2|ensembl:ENSP00000336868 intact:EBI-295799|uniprotkb:Q9P0M5|uniprotkb:Q8IW27|uniprotkb:Q6PIR0|ensembl:ENSP00000273853 psi-mi:cenpa_human(display_long)|uniprotkb:CENPA(gene name)|psi-mi:CENPA(display_short)|uniprotkb:Centromere autoantigen A(gene name synonym)|uniprotkb:Centromere protein A(gene name synonym) psi-mi:cenpc_human(display_long)|uniprotkb:CENPC(gene name)|psi-mi:CENPC(display_short)|uniprotkb:CENPC1(gene name synonym)|uniprotkb:Centromere autoantigen C(gene name synonym)|uniprotkb:Centromere protein C 1(gene name synonym)|uniprotkb:ICEN7(gene name synonym)|uniprotkb:Interphase centromere complex protein 7(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Trazzi et al. (2009) pubmed:19503796|imex:IM-26679 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-20812940|imex:IM-26679-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035891.1|refseq:NP_001800.1|dip:DIP-52297N|ensembl:ENSG00000115163(gene)|ensembl:ENST00000335756(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000939"(inner kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:3AN2|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3R45|rcsb pdb:3WTP|rcsb pdb:5CVD|rcsb pdb:5Z23|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6KDQ|rcsb pdb:6KDS|rcsb pdb:6L49|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6TEM|rcsb pdb:7D20|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 refseq:NP_001803.2|ensembl:ENSG00000145241(gene)|ensembl:ENST00000273853(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0030496"(midbody)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR025974|interpro:IPR028052|interpro:IPR028386|interpro:IPR028931|mint:Q03188|rcsb pdb:5LSJ|rcsb pdb:5LSK|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 go:"GO:0000775"(chromosome, centromeric region) - - figure legend:Fig. 8|comment:"Following the above described procedure we have performed a BiFC assay coexpressing N-GFP::HA::CENPCΔ890/943 and HA::CENPA::C-GFP. As shown in Figure 8DI we could observe only few green dots localizing at centromere positions (Figure 8DI–II) indicating a lowered efficiency level of the CENP-C/CENP-A interaction. In detail in this experiment only 25,6% of the green signal correspond to centromere positions (Figure 8G)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2018/10/29 2018/10/29 rogid:p+4MxwgHYHM9fpMXrAec/uZshTA9606 rogid:wPrWsvQ3j7zVPWsgleGrsS8O5wA9606 rigid:VmOoBq+3y0db4Xeh7UE+4gLmYTc false ha tag:n-n|cGFP:c-c nGFP:n-n|ha tag:n-n|binding-associated region:890-943 - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)