#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P55854	uniprotkb:P11474	intact:EBI-474067|uniprotkb:Q53HI9|uniprotkb:Q6FGD4|uniprotkb:Q9BWR4|uniprotkb:B2R5X4|uniprotkb:B4DUW4|ensembl:ENSP00000330343	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	psi-mi:sumo3_human(display_long)|uniprotkb:SMT3 homolog 1(gene name synonym)|uniprotkb:SUMO-2(gene name synonym)|uniprotkb:SMT3H1(gene name synonym)|uniprotkb:SUMO3(gene name)|psi-mi:SUMO3(display_short)|uniprotkb:SMT3A(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3A(gene name synonym)	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20302727|imex:IM-26400-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273345.1|refseq:NP_008867.2|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|ensembl:ENSG00000184900(gene)|ensembl:ENST00000332859(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0043392"(negative regulation of DNA binding)|interpro:IPR029071|mint:P55854|rcsb pdb:1U4A|rcsb pdb:2IO1|rcsb pdb:2MP2|rcsb pdb:6K5R|rcsb pdb:6NNQ|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-29255N	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	-	-	-	figure legend:Figure 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/03/21	2018/05/08	rogid:VQpLZsGsYa4wN8/XLGNsHsHwyQ09606	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rigid:2SSYleOhVNkpyRbfrs7mAw7J4nU	false	ha tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P55854	uniprotkb:P62508	intact:EBI-474067|uniprotkb:Q53HI9|uniprotkb:Q6FGD4|uniprotkb:Q9BWR4|uniprotkb:B2R5X4|uniprotkb:B4DUW4|ensembl:ENSP00000330343	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	psi-mi:sumo3_human(display_long)|uniprotkb:SMT3 homolog 1(gene name synonym)|uniprotkb:SUMO-2(gene name synonym)|uniprotkb:SMT3H1(gene name synonym)|uniprotkb:SUMO3(gene name)|psi-mi:SUMO3(display_short)|uniprotkb:SMT3A(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3A(gene name synonym)	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20302794|imex:IM-26400-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273345.1|refseq:NP_008867.2|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|ensembl:ENSG00000184900(gene)|ensembl:ENST00000332859(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0043392"(negative regulation of DNA binding)|interpro:IPR029071|mint:P55854|rcsb pdb:1U4A|rcsb pdb:2IO1|rcsb pdb:2MP2|rcsb pdb:6K5R|rcsb pdb:6NNQ|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-29255N	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	-	-	-	figure legend:Figure 1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/03/21	2018/05/03	rogid:VQpLZsGsYa4wN8/XLGNsHsHwyQ09606	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rigid:sNiLslOJRc4JfSzpKyvIz/p77vc	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P11474	uniprotkb:Q9UBE0	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303027|imex:IM-26400-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N	-	-	-	figure legend:Figure 2A LHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/08	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606	rigid:ZUZsSbbcMPzeL6bMpvnrG886Gdw	false	35s radiolabel:?-?|myc tag:?-?|mutation decreasing interaction rate:14-14|mutation with no effect:403-403	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P11474	uniprotkb:Q9UBT2	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	intact:EBI-718569|uniprotkb:O95605|uniprotkb:Q59H87|uniprotkb:Q6IBP6|uniprotkb:Q9NTJ1|uniprotkb:Q9UED2|uniprotkb:B3KWB9|ensembl:ENSP00000246548	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:sae2_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym)|uniprotkb:HRIHFB2115(orf name)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:UBA2(gene name)|psi-mi:UBA2(display_short)|uniprotkb:SAE2(gene name synonym)|uniprotkb:UBLE1B(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303027|imex:IM-26400-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	refseq:NP_005490.1|ensembl:ENSP00000246548|ensembl:ENST00000439527|ensembl:ENSP00000437484|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9UBT2|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:2PX9|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:4W5V|rcsb pdb:5FQ2|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|ensembl:ENSG00000126261(gene)|ensembl:ENST00000246548(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|dip:DIP-35136N	-	-	-	figure legend:Figure 2A LHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/08	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:OwedW+/kLLyyv1mwI+hjEPet+yM9606	rigid:ZUZsSbbcMPzeL6bMpvnrG886Gdw	false	35s radiolabel:?-?|myc tag:?-?|mutation decreasing interaction rate:14-14|mutation with no effect:403-403	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P11474	uniprotkb:P63165	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303027|imex:IM-26400-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N	-	-	-	figure legend:Figure 2A LHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/08	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606	rigid:ZUZsSbbcMPzeL6bMpvnrG886Gdw	false	35s radiolabel:?-?|myc tag:?-?|mutation decreasing interaction rate:14-14|mutation with no effect:403-403	sufficient binding region:1-97(IPR029071)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P11474	uniprotkb:P63279	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303027|imex:IM-26400-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Figure 2A LHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/08	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rigid:ZUZsSbbcMPzeL6bMpvnrG886Gdw	false	35s radiolabel:?-?|myc tag:?-?|mutation decreasing interaction rate:14-14|mutation with no effect:403-403	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P11474	uniprotkb:Q9UBE0	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303512|imex:IM-26400-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N	-	-	-	figure legend:Figure 2A-RHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606	rigid:fMwVAQ36Uutz1FS6MqWlCZp0+0Q	false	35s radiolabel:?-?|myc tag:?-?|mutation disrupting interaction rate:14-14|mutation with no effect:403-403	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P11474	uniprotkb:Q9UBT2	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	intact:EBI-718569|uniprotkb:O95605|uniprotkb:Q59H87|uniprotkb:Q6IBP6|uniprotkb:Q9NTJ1|uniprotkb:Q9UED2|uniprotkb:B3KWB9|ensembl:ENSP00000246548	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:sae2_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym)|uniprotkb:HRIHFB2115(orf name)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:UBA2(gene name)|psi-mi:UBA2(display_short)|uniprotkb:SAE2(gene name synonym)|uniprotkb:UBLE1B(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303512|imex:IM-26400-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	refseq:NP_005490.1|ensembl:ENSP00000246548|ensembl:ENST00000439527|ensembl:ENSP00000437484|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9UBT2|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:2PX9|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:4W5V|rcsb pdb:5FQ2|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|ensembl:ENSG00000126261(gene)|ensembl:ENST00000246548(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|dip:DIP-35136N	-	-	-	figure legend:Figure 2A-RHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:OwedW+/kLLyyv1mwI+hjEPet+yM9606	rigid:fMwVAQ36Uutz1FS6MqWlCZp0+0Q	false	35s radiolabel:?-?|myc tag:?-?|mutation disrupting interaction rate:14-14|mutation with no effect:403-403	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P11474	uniprotkb:P61956	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303512|imex:IM-26400-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N	-	-	-	figure legend:Figure 2A-RHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:WgudlZhwtQbQInv29BniecTYGY89606	rigid:fMwVAQ36Uutz1FS6MqWlCZp0+0Q	false	35s radiolabel:?-?|myc tag:?-?|mutation disrupting interaction rate:14-14|mutation with no effect:403-403	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P11474	uniprotkb:P63279	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303512|imex:IM-26400-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Figure 2A-RHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rigid:fMwVAQ36Uutz1FS6MqWlCZp0+0Q	false	35s radiolabel:?-?|myc tag:?-?|mutation disrupting interaction rate:14-14|mutation with no effect:403-403	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P62508	uniprotkb:Q9UBE0	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303735|imex:IM-26400-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N	-	-	-	figure legend:Figure 2B LHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606	rigid:FPYsXD9KOoj+CbJz490bz99EZx4	false	myc tag:?-?|35s radiolabel:?-?|mutation with no effect:360-360|mutation with no effect:439-439|mutation disrupting interaction rate:40-40	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P62508	uniprotkb:Q9UBT2	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	intact:EBI-718569|uniprotkb:O95605|uniprotkb:Q59H87|uniprotkb:Q6IBP6|uniprotkb:Q9NTJ1|uniprotkb:Q9UED2|uniprotkb:B3KWB9|ensembl:ENSP00000246548	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:sae2_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym)|uniprotkb:HRIHFB2115(orf name)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:UBA2(gene name)|psi-mi:UBA2(display_short)|uniprotkb:SAE2(gene name synonym)|uniprotkb:UBLE1B(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303735|imex:IM-26400-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	refseq:NP_005490.1|ensembl:ENSP00000246548|ensembl:ENST00000439527|ensembl:ENSP00000437484|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9UBT2|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:2PX9|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:4W5V|rcsb pdb:5FQ2|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|ensembl:ENSG00000126261(gene)|ensembl:ENST00000246548(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|dip:DIP-35136N	-	-	-	figure legend:Figure 2B LHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rogid:OwedW+/kLLyyv1mwI+hjEPet+yM9606	rigid:FPYsXD9KOoj+CbJz490bz99EZx4	false	myc tag:?-?|35s radiolabel:?-?|mutation with no effect:360-360|mutation with no effect:439-439|mutation disrupting interaction rate:40-40	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P62508	uniprotkb:P63165	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	intact:EBI-80140|uniprotkb:P55856|uniprotkb:Q6FGG0|uniprotkb:Q6NZ62|uniprotkb:Q93068|intact:EBI-28970052|ensembl:ENSP00000376076|ensembl:ENSP00000376077|uniprotkb:B2R4I5|uniprotkb:A8MUS8	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:sumo1_human(display_long)|uniprotkb:SUMO1(gene name)|psi-mi:SUMO1(display_short)|uniprotkb:Sentrin(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3C(gene name synonym)|uniprotkb:Ubiquitin-homology domain protein PIC1(gene name synonym)|uniprotkb:Ubiquitin-like protein UBL1(gene name synonym)|uniprotkb:GAP-modifying protein 1(gene name synonym)|uniprotkb:SMT3 homolog 3(gene name synonym)|uniprotkb:SMT3C(gene name synonym)|uniprotkb:SMT3H3(gene name synonym)|uniprotkb:UBL1(gene name synonym)|uniprotkb:OK/SW-cl.43(orf name)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303735|imex:IM-26400-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	refseq:NP_001005781.1|refseq:NP_003343.1|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P63165|rcsb pdb:1A5R|rcsb pdb:1TGZ|rcsb pdb:1WYW|rcsb pdb:1Y8R|rcsb pdb:1Z5S|rcsb pdb:2ASQ|rcsb pdb:2BF8|rcsb pdb:2G4D|rcsb pdb:2IO2|rcsb pdb:2IY0|rcsb pdb:2IY1|rcsb pdb:2KQS|rcsb pdb:2LAS|rcsb pdb:2MW5|rcsb pdb:2N1A|rcsb pdb:2N1V|rcsb pdb:2PE6|rcsb pdb:2UYZ|rcsb pdb:2VRR|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:3RZW|rcsb pdb:3UIP|rcsb pdb:4WJN|rcsb pdb:4WJO|rcsb pdb:4WJP|rcsb pdb:4WJQ|rcsb pdb:5AEK|rcsb pdb:5B7A|rcsb pdb:5ELJ|rcsb pdb:5GHD|rcsb pdb:6EOP|rcsb pdb:6EOT|rcsb pdb:6J4I|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6K5T|rcsb pdb:6TRW|rcsb pdb:6UYO|rcsb pdb:6UYP|rcsb pdb:6UYQ|rcsb pdb:6UYR|rcsb pdb:6UYS|ensembl:ENSG00000116030(gene)|ensembl:ENST00000392245(transcript)|ensembl:ENST00000392246(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010621"(negative regulation of transcription by transcription factor localization)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|rcsb pdb:6UYU|rcsb pdb:6UYV|rcsb pdb:6UYX|rcsb pdb:6UYY|rcsb pdb:6UYZ|rcsb pdb:6V7P|rcsb pdb:6V7Q|rcsb pdb:6V7R|rcsb pdb:6UYT|rcsb pdb:6V7S|rcsb pdb:6WW3|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-4551638|reactome:R-HSA-877312|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000392244|ensembl:ENSP00000376075|ensembl:ENSP00000376076|ensembl:ENSP00000376077|refseq:NP_001005782.1|dip:DIP-29080N	-	-	-	figure legend:Figure 2B LHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ9606	rigid:FPYsXD9KOoj+CbJz490bz99EZx4	false	myc tag:?-?|35s radiolabel:?-?|mutation with no effect:360-360|mutation with no effect:439-439|mutation disrupting interaction rate:40-40	sufficient binding region:1-97(IPR029071)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P62508	uniprotkb:P63279	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303735|imex:IM-26400-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Figure 2B LHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rigid:FPYsXD9KOoj+CbJz490bz99EZx4	false	myc tag:?-?|35s radiolabel:?-?|mutation with no effect:360-360|mutation with no effect:439-439|mutation disrupting interaction rate:40-40	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P62508	uniprotkb:Q9UBE0	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303834|imex:IM-26400-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N	-	-	-	figure legend:Figure 2B RHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606	rigid:8OCXWk24fpenRQpCU8kxt72TdA4	false	myc tag:?-?|35s radiolabel:?-?|mutation with no effect:360-360|mutation with no effect:439-439|mutation disrupting interaction rate:40-40	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P62508	uniprotkb:Q9UBT2	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	intact:EBI-718569|uniprotkb:O95605|uniprotkb:Q59H87|uniprotkb:Q6IBP6|uniprotkb:Q9NTJ1|uniprotkb:Q9UED2|uniprotkb:B3KWB9|ensembl:ENSP00000246548	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:sae2_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym)|uniprotkb:HRIHFB2115(orf name)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:UBA2(gene name)|psi-mi:UBA2(display_short)|uniprotkb:SAE2(gene name synonym)|uniprotkb:UBLE1B(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303834|imex:IM-26400-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	refseq:NP_005490.1|ensembl:ENSP00000246548|ensembl:ENST00000439527|ensembl:ENSP00000437484|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9UBT2|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:2PX9|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:4W5V|rcsb pdb:5FQ2|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|ensembl:ENSG00000126261(gene)|ensembl:ENST00000246548(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|dip:DIP-35136N	-	-	-	figure legend:Figure 2B RHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rogid:OwedW+/kLLyyv1mwI+hjEPet+yM9606	rigid:8OCXWk24fpenRQpCU8kxt72TdA4	false	myc tag:?-?|35s radiolabel:?-?|mutation with no effect:360-360|mutation with no effect:439-439|mutation disrupting interaction rate:40-40	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P62508	uniprotkb:P61956	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303834|imex:IM-26400-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N	-	-	-	figure legend:Figure 2B RHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rogid:WgudlZhwtQbQInv29BniecTYGY89606	rigid:8OCXWk24fpenRQpCU8kxt72TdA4	false	myc tag:?-?|35s radiolabel:?-?|mutation with no effect:360-360|mutation with no effect:439-439|mutation disrupting interaction rate:40-40	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P62508	uniprotkb:P63279	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	intact:EBI-80168|uniprotkb:P50550|uniprotkb:Q15698|uniprotkb:Q59GX1|uniprotkb:Q86VB3|ensembl:ENSP00000324897|ensembl:ENSP00000348056|ensembl:ENSP00000380649|ensembl:ENSP00000380650|ensembl:ENSP00000384568|ensembl:ENSP00000455893|ensembl:ENSP00000456188|ensembl:ENSP00000457064|ensembl:ENSP00000490882|ensembl:ENSP00000385009|uniprotkb:D3DU69	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:ubc9_human(display_long)|uniprotkb:UBE2I(gene name)|psi-mi:UBE2I(display_short)|uniprotkb:p18(gene name synonym)|uniprotkb:SUMO-protein ligase(gene name synonym)|uniprotkb:UBC9(gene name synonym)|uniprotkb:UBCE9(gene name synonym)|uniprotkb:Ubiquitin carrier protein 9(gene name synonym)|uniprotkb:Ubiquitin carrier protein I(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 I(gene name synonym)|uniprotkb:Ubiquitin-protein ligase I(gene name synonym)|uniprotkb:RING-type E3 SUMO transferase UBC9(gene name synonym)	psi-mi:"MI:1008"(sumoylase assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0566"(sumoylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20303834|imex:IM-26400-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	refseq:NP_003336.1|refseq:NP_919235.1|refseq:NP_919236.1|refseq:NP_919237.1|ensembl:ENSG00000103275(gene)|rcsb pdb:5D2M|rcsb pdb:5F6D|rcsb pdb:5F6E|rcsb pdb:5F6U|rcsb pdb:5F6V|rcsb pdb:5F6W|rcsb pdb:5F6X|rcsb pdb:5F6Y|rcsb pdb:5FQ2|rcsb pdb:6SYF|reactome:R-HSA-1221632|reactome:R-HSA-196791|reactome:R-HSA-3065678|reactome:R-HSA-3108214|reactome:R-HSA-3108232|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-4655427|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-8866904|reactome:R-HSA-9615933|reactome:R-HSA-9683610|reactome:R-HSA-9694631|ensembl:ENST00000325437(transcript)|ensembl:ENST00000355803(transcript)|ensembl:ENST00000397514(transcript)|ensembl:ENST00000397515(transcript)|ensembl:ENST00000403747(transcript)|ensembl:ENST00000406620(transcript)|ensembl:ENST00000562470(transcript)|ensembl:ENST00000566587(transcript)|ensembl:ENST00000567074(transcript)|ensembl:ENST00000567383(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043398"(HLH domain binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0061656"(SUMO conjugating enzyme activity)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:1903755"(positive regulation of SUMO transferase activity)|go:"GO:1990356"(sumoylated E2 ligase complex)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P63279|rcsb pdb:1A3S|rcsb pdb:1KPS|rcsb pdb:1Z5Q|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2O25|rcsb pdb:2PE6|rcsb pdb:2PX9|rcsb pdb:2XWU|rcsb pdb:3A4S|rcsb pdb:3UIN|go:"GO:1990234"(transferase complex)|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4W5V|rcsb pdb:4Y1L|refseq:XP_016879129.1|dip:DIP-29078N	-	-	-	figure legend:Figure 2B RHS|comment:It is stated that ERRa K403R was sumoylated to a level similar to the wild-type receptor, however there is a missing band for the ERRa K403R mutant.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rogid:VV8ByrWqarJUmpoBqQ9EPZiGpFo9606	rigid:8OCXWk24fpenRQpCU8kxt72TdA4	false	myc tag:?-?|35s radiolabel:?-?|mutation with no effect:360-360|mutation with no effect:439-439|mutation disrupting interaction rate:40-40	his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9UBK2	uniprotkb:P11474	intact:EBI-765486|uniprotkb:Q9UN32|uniprotkb:B7Z406|uniprotkb:I3RTT5|uniprotkb:I3RTT6|uniprotkb:I3RTT7|uniprotkb:I3RTT8|uniprotkb:I3RTT9|uniprotkb:G8DM16|uniprotkb:Q4W5M7|uniprotkb:Q3LIG1|intact:EBI-28970000|ensembl:ENSP00000264867	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	psi-mi:prgc1_human(display_long)|uniprotkb:Ligand effect modulator 6(gene name synonym)|uniprotkb:PPARGC1A(gene name)|psi-mi:PPARGC1A(display_short)|uniprotkb:LEM6(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1A(gene name synonym)|uniprotkb:PPARGC1(gene name synonym)	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20402470|imex:IM-26400-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000264867|ensembl:ENST00000506055|ensembl:ENSP00000423075|ensembl:ENST00000513205|ensembl:ENSP00000421632|ensembl:ENST00000613098|ensembl:ENSP00000481498|refseq:XP_011512073.1|refseq:NP_001317681.1|refseq:NP_001317682.1|refseq:NP_037393.1|refseq:NP_001317680.1|dip:DIP-38449N|ensembl:ENSG00000109819(gene)|ensembl:ENST00000264867(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007586"(digestion)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045333"(cellular respiration)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|mint:Q9UBK2|rcsb pdb:1XB7|rcsb pdb:3B1M|rcsb pdb:3CS8|rcsb pdb:3D24|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:4QJR|rcsb pdb:4QK4|rcsb pdb:5Q0I|rcsb pdb:5UNJ|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6FZF|rcsb pdb:6FZP|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6K0T|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6LN4|rcsb pdb:6MS7|rcsb pdb:6NWK|rcsb pdb:6NWL|rcsb pdb:6T1V|rcsb pdb:6W9K|rcsb pdb:6W9L|rcsb pdb:7E2E|rcsb pdb:7KHT|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2151209|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-8939902|reactome:R-HSA-9615017|rcsb pdb:5TWO|reactome:R-HSA-9707616	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	-	-	-	figure legend:Figure 3I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/08	rogid:kZHn8pBS+XDQNNMV7vwuyaxnquI9606	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rigid:Qqj0KhfD1Ho+X4XZWFUF8XD4+gY	false	sufficient binding region:1-250|glutathione s tranferase tag:n-n	35s radiolabel:?-?|mutation with no effect:14-14	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9UBK2	uniprotkb:P62508	intact:EBI-765486|uniprotkb:Q9UN32|uniprotkb:B7Z406|uniprotkb:I3RTT5|uniprotkb:I3RTT6|uniprotkb:I3RTT7|uniprotkb:I3RTT8|uniprotkb:I3RTT9|uniprotkb:G8DM16|uniprotkb:Q4W5M7|uniprotkb:Q3LIG1|intact:EBI-28970000|ensembl:ENSP00000264867	intact:EBI-2834260|uniprotkb:Q9UNJ4|uniprotkb:O96021|uniprotkb:A8K6I2|uniprotkb:Q68DA0|uniprotkb:Q6TS38|uniprotkb:O75454|uniprotkb:Q6PK28|uniprotkb:A8K4I0|uniprotkb:Q9R1F3|uniprotkb:Q6P274|ensembl:ENSP00000386171|uniprotkb:B3KY84|uniprotkb:E9PGB7|uniprotkb:F8W8J3	psi-mi:prgc1_human(display_long)|uniprotkb:Ligand effect modulator 6(gene name synonym)|uniprotkb:PPARGC1A(gene name)|psi-mi:PPARGC1A(display_short)|uniprotkb:LEM6(gene name synonym)|uniprotkb:PGC1(gene name synonym)|uniprotkb:PGC1A(gene name synonym)|uniprotkb:PPARGC1(gene name synonym)	psi-mi:err3_human(display_long)|uniprotkb:ESRRG(gene name)|psi-mi:ESRRG(display_short)|uniprotkb:ERR3(gene name synonym)|uniprotkb:ERRG2(gene name synonym)|uniprotkb:KIAA0832(gene name synonym)|uniprotkb:NR3B3(gene name synonym)|uniprotkb:ERR gamma-2(gene name synonym)|uniprotkb:Estrogen receptor-related protein 3(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20431986|imex:IM-26400-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000264867|ensembl:ENST00000506055|ensembl:ENSP00000423075|ensembl:ENST00000513205|ensembl:ENSP00000421632|ensembl:ENST00000613098|ensembl:ENSP00000481498|refseq:XP_011512073.1|refseq:NP_001317681.1|refseq:NP_001317682.1|refseq:NP_037393.1|refseq:NP_001317680.1|dip:DIP-38449N|ensembl:ENSG00000109819(gene)|ensembl:ENST00000264867(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007586"(digestion)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0009409"(response to cold)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014850"(response to muscle activity)|go:"GO:0014878"(response to electrical stimulus involved in regulation of muscle adaptation)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0021549"(cerebellum development)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030900"(forebrain development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043201"(response to leucine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045333"(cellular respiration)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051552"(flavone metabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071250"(cellular response to nitrite)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071332"(cellular response to fructose stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071873"(response to norepinephrine)|go:"GO:0090258"(negative regulation of mitochondrial fission)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901558"(response to metformin)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1901860"(positive regulation of mitochondrial DNA metabolic process)|go:"GO:1901863"(positive regulation of muscle tissue development)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|go:"GO:1904637"(cellular response to ionomycin)|go:"GO:1904639"(cellular response to resveratrol)|go:"GO:1904640"(response to methionine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000184"(positive regulation of progesterone biosynthetic process)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034605|interpro:IPR034625|interpro:IPR034833|interpro:IPR035979|mint:Q9UBK2|rcsb pdb:1XB7|rcsb pdb:3B1M|rcsb pdb:3CS8|rcsb pdb:3D24|rcsb pdb:3U9Q|rcsb pdb:3V9T|rcsb pdb:3V9V|rcsb pdb:4QJR|rcsb pdb:4QK4|rcsb pdb:5Q0I|rcsb pdb:5UNJ|rcsb pdb:5Z5S|rcsb pdb:5Z6S|rcsb pdb:6AD9|rcsb pdb:6FZF|rcsb pdb:6FZP|rcsb pdb:6IZM|rcsb pdb:6IZN|rcsb pdb:6K0T|rcsb pdb:6KXX|rcsb pdb:6KXY|rcsb pdb:6LN4|rcsb pdb:6MS7|rcsb pdb:6NWK|rcsb pdb:6NWL|rcsb pdb:6T1V|rcsb pdb:6W9K|rcsb pdb:6W9L|rcsb pdb:7E2E|rcsb pdb:7KHT|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2151209|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-8939902|reactome:R-HSA-9615017|rcsb pdb:5TWO|reactome:R-HSA-9707616	refseq:XP_011507569.1|refseq:XP_011507570.1|refseq:XP_011507571.1|refseq:XP_011507576.1|refseq:XP_011507577.1|refseq:XP_011507578.1|refseq:XP_011507579.1|refseq:XP_011507580.1|refseq:XP_011507581.1|refseq:XP_011507582.1|refseq:XP_016856120.1|refseq:NP_001230434.1|refseq:NP_001230435.1|refseq:NP_001230436.1|refseq:NP_001230447.1|refseq:XP_016856121.1|ensembl:ENSG00000196482(gene)|ensembl:ENST00000408911(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0050682"(AF-2 domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|mint:P62508|rcsb pdb:1KV6|rcsb pdb:1TFC|rcsb pdb:1VJB|rcsb pdb:2E2R|rcsb pdb:2EWP|rcsb pdb:2GP7|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:2GPU|rcsb pdb:2GPV|rcsb pdb:2P7A|rcsb pdb:2P7G|rcsb pdb:2P7Z|rcsb pdb:2ZAS|rcsb pdb:2ZBS|rcsb pdb:2ZKC|rcsb pdb:5YSO|rcsb pdb:6A6K|rcsb pdb:6I61|rcsb pdb:6I62|rcsb pdb:6I63|rcsb pdb:6I64|rcsb pdb:6I65|rcsb pdb:6I66|rcsb pdb:6I67|rcsb pdb:6K3N|rcsb pdb:6KNR|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y3W|rcsb pdb:6Y58|reactome:R-HSA-383280|go:"GO:0005654"(nucleoplasm)|refseq:NP_001127757.1|refseq:NP_001230438.1|refseq:NP_001230439.1|refseq:NP_001230440.1|refseq:NP_001230441.1|refseq:NP_001230442.1|refseq:NP_001230443.1|refseq:NP_001230444.1|refseq:NP_001230448.1|refseq:NP_001429.2|refseq:NP_996317.1|refseq:NP_996318.1|refseq:XP_016856122.1|refseq:XP_016856123.1|refseq:XP_016856124.1|refseq:XP_016856125.1|refseq:XP_016856126.1|refseq:XP_016856127.1|refseq:XP_016856128.1|refseq:XP_016856130.1|refseq:XP_016856133.1|refseq:XP_016856134.1|refseq:XP_016856129.1|refseq:XP_016856131.1|refseq:XP_016856132.1|refseq:XP_016856135.1|refseq:XP_016856136.1|refseq:XP_016856137.1|refseq:XP_016856138.1	-	-	-	figure legend:Figure 3I-2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:kZHn8pBS+XDQNNMV7vwuyaxnquI9606	rogid:BMdGghKpGbkmaSL6DR6ApJU6Exk9606	rigid:oSXztI3XoTEo1uIEvFsT3KzIlYA	false	sufficient binding region:1-250|glutathione s tranferase tag:n-n	35s radiolabel:?-?|mutation with no effect:40-40	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P11474	uniprotkb:P55854	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	intact:EBI-474067|uniprotkb:Q53HI9|uniprotkb:Q6FGD4|uniprotkb:Q9BWR4|uniprotkb:B2R5X4|uniprotkb:B4DUW4|ensembl:ENSP00000330343	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:sumo3_human(display_long)|uniprotkb:SMT3 homolog 1(gene name synonym)|uniprotkb:SUMO-2(gene name synonym)|uniprotkb:SMT3H1(gene name synonym)|uniprotkb:SUMO3(gene name)|psi-mi:SUMO3(display_short)|uniprotkb:SMT3A(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3A(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20466232|imex:IM-26400-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	refseq:NP_001273345.1|refseq:NP_008867.2|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|ensembl:ENSG00000184900(gene)|ensembl:ENST00000332859(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031386"(protein tag)|go:"GO:0043392"(negative regulation of DNA binding)|interpro:IPR029071|mint:P55854|rcsb pdb:1U4A|rcsb pdb:2IO1|rcsb pdb:2MP2|rcsb pdb:6K5R|rcsb pdb:6NNQ|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|dip:DIP-29255N	-	-	-	figure legend:Figure 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2018/03/21	2018/05/09	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rogid:VQpLZsGsYa4wN8/XLGNsHsHwyQ09606	rigid:2SSYleOhVNkpyRbfrs7mAw7J4nU	false	green fluorescent protein tag:n-n|mutation with no effect:14-14	ha tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:P11474	intact:EBI-20557335	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	-	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:erre_probe(display_short)|psi-mi:EBI-20557335(display_long)	psi-mi:"MI:0412"(electrophoretic mobility supershift assay)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20557330|imex:IM-26400-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	-	-	-	-	figure legend:figure 4B|comment:No change in the DNA binding pattern was observed by addition of purified GST-PGC-1a/1–250 fusion protein.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/03/21	2018/05/03	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	-	-	false	myc tag:?-?|mutation with no effect:403-403|mutation with no effect:14-14	32p radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q8N2W9	uniprotkb:P11474	intact:EBI-473160|uniprotkb:O75926|uniprotkb:Q96G19|uniprotkb:Q9UN16|intact:EBI-28970184|ensembl:ENSP00000262971	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	psi-mi:pias4_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein gamma(gene name synonym)|uniprotkb:PIASy(gene name synonym)|uniprotkb:PIAS4(gene name)|psi-mi:PIAS4(display_short)|uniprotkb:PIASG(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS4(gene name synonym)	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20557640|imex:IM-26400-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105229(gene)|ensembl:ENST00000262971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|ensembl:ENSP00000262971|refseq:NP_056981.2|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990234"(transferase complex)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027224|interpro:IPR036361|interpro:IPR038654|reactome:R-HSA-196791|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|dip:DIP-32499N	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	-	-	-	figure legend:Figure 6B|comment:A band that is stated to show probable sumoylation of ERRa  on Lys-14 is shown.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/03/21	2018/05/04	rogid:/1DLDSbuYFdXVUmENWJvNI7WqcQ9606	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rigid:PDHoUmXKktMz8YmibgxK7mWs3lE	false	flag tag:?-?	sumoylated lysine:?-?|myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N2W9	uniprotkb:P11474	intact:EBI-473160|uniprotkb:O75926|uniprotkb:Q96G19|uniprotkb:Q9UN16|intact:EBI-28970184|ensembl:ENSP00000262971	intact:EBI-372412|uniprotkb:Q14514|ensembl:ENSP00000000442|ensembl:ENSP00000384851	psi-mi:pias4_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein gamma(gene name synonym)|uniprotkb:PIASy(gene name synonym)|uniprotkb:PIAS4(gene name)|psi-mi:PIAS4(display_short)|uniprotkb:PIASG(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS4(gene name synonym)	psi-mi:err1_human(display_long)|uniprotkb:Estrogen-related receptor alpha(gene name synonym)|uniprotkb:Estrogen receptor-like 1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group B member 1(gene name synonym)|uniprotkb:ESRRA(gene name)|psi-mi:ESRRA(display_short)|uniprotkb:ERR1(gene name synonym)|uniprotkb:ESRL1(gene name synonym)|uniprotkb:NR3B1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tremblay et al. (2008)	pubmed:18063693|imex:IM-26400	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20557681|imex:IM-26400-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105229(gene)|ensembl:ENST00000262971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|ensembl:ENSP00000262971|refseq:NP_056981.2|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1990234"(transferase complex)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027224|interpro:IPR036361|interpro:IPR038654|reactome:R-HSA-196791|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|dip:DIP-32499N	refseq:NP_004442.3|refseq:NP_001269379.1|refseq:NP_001269380.1|dip:DIP-35053N|ensembl:ENSG00000173153(gene)|ensembl:ENST00000000442(transcript)|ensembl:ENST00000405666(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0032355"(response to estradiol)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051216"(cartilage development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR027289|interpro:IPR035500|rcsb pdb:1XB7|rcsb pdb:2PJL|rcsb pdb:3D24|rcsb pdb:3K6P|rcsb pdb:7E2E|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-383280|reactome:R-HSA-8939902	-	-	-	figure legend:Figure 6Bi|comment:No  sumoylation  is shown.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2018/03/21	2018/05/04	rogid:/1DLDSbuYFdXVUmENWJvNI7WqcQ9606	rogid:8j6Uo6uL0aWefXFicF/Y/HSL7WI9606	rigid:PDHoUmXKktMz8YmibgxK7mWs3lE	false	flag tag:?-?	myc tag:?-?|mutation:14-14	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)