#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UGU0	uniprotkb:Q92547	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560420|imex:IM-26432-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/14	2018/05/14	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:mLchm3WvgK9vZo3f3NbwlDLEnn8	false	myc tag:?-?|35s radiolabel:?-?	35s radiolabel:?-?|ha tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9UGU0	uniprotkb:Q92547	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560483|imex:IM-26432-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/05/14	2018/05/14	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:mLchm3WvgK9vZo3f3NbwlDLEnn8	false	sufficient binding region:1837-1960(IPR013083)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UGU0	uniprotkb:Q92547	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560504|imex:IM-26432-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/14	2018/05/14	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:mLchm3WvgK9vZo3f3NbwlDLEnn8	false	glutathione s tranferase tag:?-?|sufficient binding region:1837-1960(IPR013083)	sufficient binding region:862-1406|ha tag:?-?|35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9UGU0	uniprotkb:Q92547	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560524|imex:IM-26432-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig 1D, 1E, 1F|comment:Complete removal of DNA by treatment with the nuclease benzonase had no effect on the interaction between SPBP and TopBP|comment:"The SPBP(1333–1666) region interacts weakly with TopBP1."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/05/14	2018/05/14	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:mLchm3WvgK9vZo3f3NbwlDLEnn8	false	ha tag:?-?|sufficient binding region:1333-1666(IPR034732)|35s radiolabel:?-?	sufficient binding region:862-1011(IPR036420)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9UGU0	uniprotkb:Q92547	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560548|imex:IM-26432-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2018/05/14	2018/05/14	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:mLchm3WvgK9vZo3f3NbwlDLEnn8	false	green fluorescent protein tag:?-?(IPR034732)	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UGU0	uniprotkb:Q92547	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560562|imex:IM-26432-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig. 2C|comment:Both GFP-tagged and endogenous TCF20 were present in the cell, it is not possible to tell in this experiment which was present in the immunoprecipitate.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2018/05/14	2018/05/14	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:mLchm3WvgK9vZo3f3NbwlDLEnn8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92547	uniprotkb:Q9UGU0	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560577|imex:IM-26432-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	-	-	-	figure legend:Fig. 2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2018/05/14	2018/05/15	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	rigid:mLchm3WvgK9vZo3f3NbwlDLEnn8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q92547	uniprotkb:Q9UGU0	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560577|imex:IM-26432-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	-	-	-	figure legend:Fig. 2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2018/05/14	2018/05/15	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	rigid:mLchm3WvgK9vZo3f3NbwlDLEnn8	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
ensembl:ENSG00000136997	uniprotkb:Q9UGU0	intact:EBI-1265559	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	psi-mi:myc_human_gene(display_short)|psi-mi:ENSG00000136997(display_long)	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560597|imex:IM-26432-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	-	-	-	figure legend:Fig. 3B|comment:Both GFP-tagged and endogenous TCF20 were present in the cell, it is not possible to tell in this experiment which was present in the immunoprecipitate.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2018/05/14	2018/05/15	-	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000136997	uniprotkb:Q92547	intact:EBI-1265559	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:myc_human_gene(display_short)|psi-mi:ENSG00000136997(display_long)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560717|imex:IM-26432-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2018/05/14	2018/05/15	-	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000149968	uniprotkb:Q9UGU0	intact:EBI-2677262	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	psi-mi:mmp3_human_gene(display_short)|psi-mi:ENSG00000149968(display_long)	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560864|imex:IM-26432-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	-	-	-	figure legend:Fig. 4D|comment:Both GFP-tagged and endogenous TCF20 were present in the cell, it is not possible to tell in this experiment which was present in the immunoprecipitate.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2018/05/14	2018/05/15	-	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000149968	uniprotkb:Q92547	intact:EBI-2677262	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:mmp3_human_gene(display_short)|psi-mi:ENSG00000149968(display_long)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560873|imex:IM-26432-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2018/05/14	2018/05/15	-	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSG00000149968	uniprotkb:P14921	intact:EBI-2677262	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:mmp3_human_gene(display_short)|psi-mi:ENSG00000149968(display_long)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560885|imex:IM-26432-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	-	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2018/05/14	2018/05/15	-	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	-	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9UGU0	uniprotkb:Q92547	intact:EBI-3444158|uniprotkb:Q9H4M0|uniprotkb:Q4V353|uniprotkb:Q13078|uniprotkb:O14528|uniprotkb:A9JX12|ensembl:ENSP00000352463|ensembl:ENSP00000460328|ensembl:ENSP00000483199|ensembl:ENSP00000487296|ensembl:ENSP00000487302|ensembl:ENSP00000489215|ensembl:ENSP00000489614|ensembl:ENSP00000490305|ensembl:ENSP00000503828|ensembl:ENSP00000508272	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:tcf20_human(display_long)|uniprotkb:TCF20(gene name)|psi-mi:TCF20(display_short)|uniprotkb:KIAA0292(gene name synonym)|uniprotkb:SPBP(gene name synonym)|uniprotkb:Nuclear factor SPBP(gene name synonym)|uniprotkb:Protein AR1(gene name synonym)|uniprotkb:Stromelysin-1 PDGF-responsive element-binding protein(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560914|imex:IM-26432-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528656.1|refseq:XP_006724376.1|refseq:NP_005641.1|refseq:NP_852469.1|ensembl:ENSG00000100207(gene)|ensembl:ENSG00000262024(gene)|ensembl:ENSG00000276461(gene)|ensembl:ENSG00000280467(gene)|ensembl:ENSG00000281897(gene)|ensembl:ENSG00000282892(gene)|ensembl:ENSG00000283026(gene)|ensembl:ENSG00000283681(gene)|ensembl:ENST00000359486(transcript)|ensembl:ENST00000574943(transcript)|ensembl:ENST00000621408(transcript)|ensembl:ENST00000626726(transcript)|ensembl:ENST00000628774(transcript)|ensembl:ENST00000634616(transcript)|ensembl:ENST00000635146(transcript)|ensembl:ENST00000636799(transcript)|ensembl:ENST00000677622(transcript)|ensembl:ENST00000683686(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR041972|mint:Q9UGU0|refseq:XP_005261779.1	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig. 7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/05/14	2018/05/15	rogid:h+PDFg/Ak1TJeM/o6G/gTp/wc4E9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:mLchm3WvgK9vZo3f3NbwlDLEnn8	false	sufficient binding region:1837-1960(IPR013083)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03164	uniprotkb:Q92547	intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560922|imex:IM-26432-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig. 7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/05/14	2018/05/15	rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:7ZIkQYTJReVu4VEJAWCHiYimkU8	false	sufficient binding region:1431..1431-1978(IPR034732)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14686	uniprotkb:Q92547	intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560936|imex:IM-26432-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig. 7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/05/14	2018/05/15	rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:kjT7g2RtzQErElawNe4ZFASrEMU	false	sufficient binding region:170..170-5137..5137	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UMN6	uniprotkb:Q92547	intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837	intact:EBI-308302|uniprotkb:Q7LGC1|uniprotkb:Q9UEB9|uniprotkb:B7Z7W8|ensembl:ENSP00000260810	psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym)	psi-mi:topb1_human(display_long)|uniprotkb:KIAA0259(gene name synonym)|uniprotkb:TOPBP1(gene name)|psi-mi:TOPBP1(display_short)|uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)|uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Sjøttem et al. (2006)	pubmed:17913746|imex:IM-26432	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-20560951|imex:IM-26432-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000398837|dip:DIP-34598N|ensembl:ENSG00000272333(gene)|ensembl:ENST00000420124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459	refseq:NP_008958.2|ensembl:ENSG00000163781(gene)|ensembl:ENST00000260810(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000922"(spindle pole)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001357(BRCT)|interpro:IPR035960|interpro:IPR036420|interpro:IPR044737|mint:Q92547|rcsb pdb:1WF6|rcsb pdb:2XNH|rcsb pdb:2XNK|rcsb pdb:3AL2|rcsb pdb:3AL3|rcsb pdb:3JVE|rcsb pdb:3OLC|rcsb pdb:3PD7|rcsb pdb:3UEN|rcsb pdb:3UEO|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:7CMZ|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_016861125.1|dip:DIP-24263N	-	-	-	figure legend:Fig. 7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2018/05/14	2018/05/15	rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606	rogid:QlPHW0dd/u8bQgAUNVnsjcsO+Bk9606	rigid:ZxRhql9Esscww4sfRLZN8rkWuJ8	false	sufficient binding region:1201..1201-1686(IPR034732)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)