#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q15788	uniprotkb:Q13569	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173397|imex:IM-26384-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	-	-	figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2018/04/13	2018/04/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rigid:edVoa62GLzTtcV9gd9YIAR44XNg	false	ha tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15788	uniprotkb:Q13569	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173407|imex:IM-26384-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	-	-	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2018/04/13	2018/04/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rigid:edVoa62GLzTtcV9gd9YIAR44XNg	false	ha tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q15788-2	uniprotkb:Q13569	intact:EBI-5327712|ensembl:ENSP00000288599|ensembl:ENSP00000385097	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:q15788-2(display_long)|uniprotkb:SRC-1E(isoform synonym)|uniprotkb:SRC1e(isoform synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173422|imex:IM-26384-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-455189(isoform-parent)|ensembl:ENSG00000084676(gene)|ensembl:ENST00000405141(transcript)|ensembl:ENST00000288599(transcript)|uniprotkb:Q15788-2(isoform-parent)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	isoform-comment:"Major form. Contains a domain at its C-terminus (1241-1399) that is able to mediate transactivation."	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/04/13	2018/04/13	rogid:45R2VkXyvB1q0fa69XlCw0HVVs09606	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rigid:CbyhykhdUnsaaP6CQSCTIGpXIxQ	false	glutathione s tranferase tag:?-?|sufficient binding region:989-1106	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q15788	uniprotkb:P19785	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-346765|uniprotkb:Q9JJT5|uniprotkb:Q9QY51|uniprotkb:Q9QY52|ensembl:ENSMUSP00000070070|ensembl:ENSMUSP00000101214|ensembl:ENSMUSP00000101215	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:esr1_mouse(display_long)|uniprotkb:Esr1(gene name)|psi-mi:Esr1(display_short)|uniprotkb:Esr(gene name synonym)|uniprotkb:Estr(gene name synonym)|uniprotkb:Estra(gene name synonym)|uniprotkb:Nr3a1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173434|imex:IM-26384-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	refseq:XP_011241368.1|refseq:XP_011241369.1|refseq:XP_011241370.1|refseq:NP_031982.1|refseq:NP_001289460.1|refseq:NP_001289461.1|refseq:XP_006512496.1|refseq:XP_006512497.1|refseq:XP_006512498.1|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-5689896|reactome:R-MMU-6811558|reactome:R-MMU-8866910|reactome:R-MMU-8931987|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9018519|reactome:R-MMU-1257604|go:"GO:0035327"|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042562"(hormone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060011"(Sertoli cell proliferation)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P19785|reactome:R-MMU-1251985|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|ensembl:ENSMUSG00000019768(gene)|ensembl:ENSMUST00000067086(transcript)|ensembl:ENSMUST00000105589(transcript)|ensembl:ENSMUST00000105590(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030315"(T-tubule)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031798"(type 1 metabotropic glutamate receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)	-	-	-	figure legend:Fig.2B|comment:the interaction occurs only with E2 treatment|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/04/13	2018/04/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:rGimZuxFcndkD0fWkLb/pZLxcZc10090	rigid:06bdp00MiWS8hrbPqQcHH503/V8	false	glutathione s tranferase tag:?-?|sufficient binding region:1241-1399|sufficient binding region:570-780	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q15788	uniprotkb:Q13569	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173448|imex:IM-26384-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	-	-	figure legend:Fig.2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/04/13	2018/04/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rigid:edVoa62GLzTtcV9gd9YIAR44XNg	false	glutathione s tranferase tag:?-?|sufficient binding region:989-1240	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q15788	uniprotkb:Q13569	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173583|imex:IM-26384-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	-	-	figure legend:Fig.3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/04/13	2018/04/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rigid:edVoa62GLzTtcV9gd9YIAR44XNg	false	glutathione s tranferase tag:?-?|sufficient binding region:989-1240	mutation decreasing interaction strength:342-342,346-346|mutation decreasing interaction strength:346-346,342-342|35s radiolabel:?-?|mutation decreasing interaction strength:334-334,338-338|mutation decreasing interaction strength:334-334,338-338|mutation disrupting interaction strength:334-334,338-338,342-342,346-346|mutation disrupting interaction strength:334-334,338-338,342-342,346-346|mutation with no effect:351-351,356-356	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P19785	uniprotkb:Q13569	intact:EBI-346765|uniprotkb:Q9JJT5|uniprotkb:Q9QY51|uniprotkb:Q9QY52|ensembl:ENSMUSP00000070070|ensembl:ENSMUSP00000101214|ensembl:ENSMUSP00000101215	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:esr1_mouse(display_long)|uniprotkb:Esr1(gene name)|psi-mi:Esr1(display_short)|uniprotkb:Esr(gene name synonym)|uniprotkb:Estr(gene name synonym)|uniprotkb:Estra(gene name synonym)|uniprotkb:Nr3a1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173640|imex:IM-26384-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011241368.1|refseq:XP_011241369.1|refseq:XP_011241370.1|refseq:NP_031982.1|refseq:NP_001289460.1|refseq:NP_001289461.1|refseq:XP_006512496.1|refseq:XP_006512497.1|refseq:XP_006512498.1|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-5689896|reactome:R-MMU-6811558|reactome:R-MMU-8866910|reactome:R-MMU-8931987|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9018519|reactome:R-MMU-1257604|go:"GO:0035327"|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042562"(hormone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060011"(Sertoli cell proliferation)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P19785|reactome:R-MMU-1251985|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|ensembl:ENSMUSG00000019768(gene)|ensembl:ENSMUST00000067086(transcript)|ensembl:ENSMUST00000105589(transcript)|ensembl:ENSMUST00000105590(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030315"(T-tubule)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031798"(type 1 metabotropic glutamate receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	-	-	figure legend:Fig.3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/04/13	2018/04/13	rogid:rGimZuxFcndkD0fWkLb/pZLxcZc10090	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rigid:81MsHUgQCCBy4ooVUO2UTnnV9Qs	false	glutathione s tranferase tag:?-?	mutation with no effect:342-342,346-346|mutation with no effect:346-346,342-342|35s radiolabel:?-?|mutation with no effect:334-334,338-338|mutation with no effect:334-334,338-338|mutation with no effect:334-334,338-338,342-342,346-346|mutation with no effect:334-334,338-338,342-342,346-346|mutation with no effect:351-351,356-356	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q15788	uniprotkb:Q13569	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173691|imex:IM-26384-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	-	-	figure legend:Fig.3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/04/13	2018/04/16	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rigid:edVoa62GLzTtcV9gd9YIAR44XNg	false	glutathione s tranferase tag:?-?	35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q15788	uniprotkb:Q13569	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173691|imex:IM-26384-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	-	-	figure legend:Fig.3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/04/13	2018/04/16	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rigid:edVoa62GLzTtcV9gd9YIAR44XNg	false	glutathione s tranferase tag:?-?	sufficient binding region:330-346|mutation disrupting interaction strength:334-334,338-338,342-342,346-346|mutation with no effect:351-351,356-356	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q13569	uniprotkb:Q15788-2	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	intact:EBI-5327712|ensembl:ENSP00000288599|ensembl:ENSP00000385097	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:q15788-2(display_long)|uniprotkb:SRC-1E(isoform synonym)|uniprotkb:SRC1e(isoform synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173759|imex:IM-26384-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	intact:EBI-455189(isoform-parent)|ensembl:ENSG00000084676(gene)|ensembl:ENST00000405141(transcript)|ensembl:ENST00000288599(transcript)|uniprotkb:Q15788-2(isoform-parent)	-	-	isoform-comment:"Major form. Contains a domain at its C-terminus (1241-1399) that is able to mediate transactivation."	figure legend:Fig. 4B, 4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/04/13	2018/04/16	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rogid:45R2VkXyvB1q0fa69XlCw0HVVs09606	rigid:CbyhykhdUnsaaP6CQSCTIGpXIxQ	false	glutathione s tranferase tag:?-?	35s radiolabel:?-?|mutation disrupting interaction strength:1169-1169|mutation decreasing interaction strength:991-991|mutation disrupting interaction strength:991-991,1169-1169	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q13569	uniprotkb:Q15788	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173776|imex:IM-26384-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	-	-	-	figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2018/04/13	2018/04/16	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rigid:edVoa62GLzTtcV9gd9YIAR44XNg	false	glutathione s tranferase tag:?-?	glutathione s tranferase tag:?-?|mutation decreasing interaction strength:1169-1169|mutation decreasing interaction strength:991-991|mutation decreasing interaction strength:991-991,1169-1169|sufficient binding region:989-1240	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q15788	uniprotkb:P56581	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-4320525|uniprotkb:Q3TPW4|uniprotkb:Q542A9|uniprotkb:Q5U3M4|uniprotkb:Q5U3M5|uniprotkb:Q6PJW4|uniprotkb:Q8BPK0|ensembl:ENSMUSP00000121000	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_mouse(display_long)|uniprotkb:Tdg(gene name)|psi-mi:Tdg(display_short)|uniprotkb:C-JUN leucine zipper interactive protein JZA-3(gene name synonym)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173466|imex:IM-26384-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	refseq:NP_035691.2|refseq:NP_766140.2|ensembl:ENSMUSG00000034674(gene)|ensembl:ENSMUST00000151390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0016605"(PML body)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|reactome:R-MMU-110329|reactome:R-MMU-110357|reactome:R-MMU-3108214|reactome:R-MMU-5221030|go:"GO:0003677"(DNA binding)|dip:DIP-216N	-	-	-	figure legend:Fig. 3A, 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/04/13	2018/04/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:zR76gYnkGSSFMFlHrLeYV5zuxz810090	rigid:S97oxQYyyrh/qT48sMKc8W9CsKc	false	sufficient binding region:989-1240	necessary binding region:307-338	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15788	uniprotkb:P56581	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-4320525|uniprotkb:Q3TPW4|uniprotkb:Q542A9|uniprotkb:Q5U3M4|uniprotkb:Q5U3M5|uniprotkb:Q6PJW4|uniprotkb:Q8BPK0|ensembl:ENSMUSP00000121000	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_mouse(display_long)|uniprotkb:Tdg(gene name)|psi-mi:Tdg(display_short)|uniprotkb:C-JUN leucine zipper interactive protein JZA-3(gene name synonym)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173489|imex:IM-26384-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	refseq:NP_035691.2|refseq:NP_766140.2|ensembl:ENSMUSG00000034674(gene)|ensembl:ENSMUST00000151390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0016605"(PML body)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|reactome:R-MMU-110329|reactome:R-MMU-110357|reactome:R-MMU-3108214|reactome:R-MMU-5221030|go:"GO:0003677"(DNA binding)|dip:DIP-216N	-	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/04/13	2018/04/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:zR76gYnkGSSFMFlHrLeYV5zuxz810090	rigid:S97oxQYyyrh/qT48sMKc8W9CsKc	false	sufficient binding region:989-1240	mutation decreasing interaction strength:349-349,345-345|mutation decreasing interaction strength:353-353,357-357|mutation decreasing interaction strength:345-345,349-349,353-353,357-357	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15788	uniprotkb:P56581	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-4320525|uniprotkb:Q3TPW4|uniprotkb:Q542A9|uniprotkb:Q5U3M4|uniprotkb:Q5U3M5|uniprotkb:Q6PJW4|uniprotkb:Q8BPK0|ensembl:ENSMUSP00000121000	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_mouse(display_long)|uniprotkb:Tdg(gene name)|psi-mi:Tdg(display_short)|uniprotkb:C-JUN leucine zipper interactive protein JZA-3(gene name synonym)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173527|imex:IM-26384-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	refseq:NP_035691.2|refseq:NP_766140.2|ensembl:ENSMUSG00000034674(gene)|ensembl:ENSMUST00000151390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0016605"(PML body)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|reactome:R-MMU-110329|reactome:R-MMU-110357|reactome:R-MMU-3108214|reactome:R-MMU-5221030|go:"GO:0003677"(DNA binding)|dip:DIP-216N	-	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2018/04/13	2018/04/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:zR76gYnkGSSFMFlHrLeYV5zuxz810090	rigid:S97oxQYyyrh/qT48sMKc8W9CsKc	false	sufficient binding region:989-1240|mutation decreasing interaction strength:991-991|mutation decreasing interaction strength:1169-1169|mutation decreasing interaction strength:991-991,1169-1169	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15788	uniprotkb:P56581	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-4320525|uniprotkb:Q3TPW4|uniprotkb:Q542A9|uniprotkb:Q5U3M4|uniprotkb:Q5U3M5|uniprotkb:Q6PJW4|uniprotkb:Q8BPK0|ensembl:ENSMUSP00000121000	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_mouse(display_long)|uniprotkb:Tdg(gene name)|psi-mi:Tdg(display_short)|uniprotkb:C-JUN leucine zipper interactive protein JZA-3(gene name synonym)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173552|imex:IM-26384-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	refseq:NP_035691.2|refseq:NP_766140.2|ensembl:ENSMUSG00000034674(gene)|ensembl:ENSMUST00000151390(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0016605"(PML body)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|reactome:R-MMU-110329|reactome:R-MMU-110357|reactome:R-MMU-3108214|reactome:R-MMU-5221030|go:"GO:0003677"(DNA binding)|dip:DIP-216N	-	-	-	figure legend:Fig. 3E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2018/04/13	2018/04/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:zR76gYnkGSSFMFlHrLeYV5zuxz810090	rigid:S97oxQYyyrh/qT48sMKc8W9CsKc	false	sufficient binding region:989-1240	mutation decreasing interaction strength:349-349,345-345|mutation decreasing interaction strength:353-353,357-357|mutation decreasing interaction strength:345-345,349-349,353-353,357-357|mutation with no effect:151-151|mutation with no effect:144-144,146-146,147-147|mutation decreasing interaction strength:353-353,357-357|mutation decreasing interaction strength:345-345,349-349,353-353,357-357	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P03372	uniprotkb:Q13569	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173823|imex:IM-26384-28	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/04/16	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	-	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P03372	ensembl:ENSG00000082175	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	intact:EBI-17173825	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	uniprotkb:PGR(gene name)|psi-mi:PGR(display_short)|uniprotkb:NR3C3(gene name synonym)|ensembl:prgr_human_gene(shortlabel)|psi-mi:ENSG00000082175(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173823|imex:IM-26384-28	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	refseq:NP_000917.3|refseq:NP_001189403.1|refseq:NP_001258090.1|refseq:NP_001258091.1	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/04/16	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	-	-	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q15788	uniprotkb:Q13569	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173838|imex:IM-26384-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/04/16	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	-	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q15788	ensembl:ENSG00000082175	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-17173825	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	uniprotkb:PGR(gene name)|psi-mi:PGR(display_short)|uniprotkb:NR3C3(gene name synonym)|ensembl:prgr_human_gene(shortlabel)|psi-mi:ENSG00000082175(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173838|imex:IM-26384-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	refseq:NP_000917.3|refseq:NP_001189403.1|refseq:NP_001258090.1|refseq:NP_001258091.1	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/04/16	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	-	-	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P03372	uniprotkb:Q15788	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173846|imex:IM-26384-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/04/16	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	-	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P03372	ensembl:ENSG00000082175	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	intact:EBI-17173825	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	uniprotkb:PGR(gene name)|psi-mi:PGR(display_short)|uniprotkb:NR3C3(gene name synonym)|ensembl:prgr_human_gene(shortlabel)|psi-mi:ENSG00000082175(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173846|imex:IM-26384-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	refseq:NP_000917.3|refseq:NP_001189403.1|refseq:NP_001258090.1|refseq:NP_001258091.1	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/04/16	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	-	-	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q13569	uniprotkb:Q15788	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173853|imex:IM-26384-34	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/04/16	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	-	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q13569	ensembl:ENSG00000082175	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	intact:EBI-17173825	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	uniprotkb:PGR(gene name)|psi-mi:PGR(display_short)|uniprotkb:NR3C3(gene name synonym)|ensembl:prgr_human_gene(shortlabel)|psi-mi:ENSG00000082175(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173853|imex:IM-26384-34	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	refseq:NP_000917.3|refseq:NP_001189403.1|refseq:NP_001258090.1|refseq:NP_001258091.1	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/04/16	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	-	-	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q15788	ensembl:ENSG00000082175	intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216	intact:EBI-17173825	psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym)	uniprotkb:PGR(gene name)|psi-mi:PGR(display_short)|uniprotkb:NR3C3(gene name synonym)|ensembl:prgr_human_gene(shortlabel)|psi-mi:ENSG00000082175(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173860|imex:IM-26384-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)	refseq:NP_000917.3|refseq:NP_001189403.1|refseq:NP_001258090.1|refseq:NP_001258091.1	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/09/13	rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606	-	-	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q13569	ensembl:ENSG00000082175	intact:EBI-348333|ensembl:ENSP00000376611|uniprotkb:Q8IUZ6|uniprotkb:Q8IZM3	intact:EBI-17173825	psi-mi:tdg_human(display_long)|uniprotkb:TDG(gene name)|psi-mi:TDG(display_short)|uniprotkb:Thymine-DNA glycosylase(gene name synonym)	uniprotkb:PGR(gene name)|psi-mi:PGR(display_short)|uniprotkb:NR3C3(gene name synonym)|ensembl:prgr_human_gene(shortlabel)|psi-mi:ENSG00000082175(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-17173867|imex:IM-26384-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENSG00000139372(gene)|ensembl:ENST00000392872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006284"(base-excision repair)|go:"GO:0006285"(base-excision repair, AP site formation)|go:"GO:0006298"(mismatch repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0032183"(SUMO binding)|go:"GO:0035511"(oxidative DNA demethylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043739"(G/U mismatch-specific uracil-DNA glycosylase activity)|go:"GO:0045008"(depyrimidination)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0080111"(DNA demethylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902544"(regulation of DNA N-glycosylase activity)|interpro:IPR003310("G:T/U mismatch-specific DNA glycosylase")|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR015637(DNA glycosylase, G/T mismatch)|interpro:IPR036895|mint:Q13569|rcsb pdb:1WYW|rcsb pdb:2D07|rcsb pdb:2RBA|rcsb pdb:3UFJ|rcsb pdb:3UO7|rcsb pdb:3UOB|rcsb pdb:4FNC|rcsb pdb:4JGC|rcsb pdb:4XEG|rcsb pdb:4Z3A|rcsb pdb:4Z47|rcsb pdb:4Z7B|rcsb pdb:4Z7Z|rcsb pdb:5CYS|rcsb pdb:5FF8|rcsb pdb:5HF7|rcsb pdb:5JXY|rcsb pdb:5T2W|rcsb pdb:6U15|rcsb pdb:6U16|rcsb pdb:6U17|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|reactome:R-HSA-3108214|reactome:R-HSA-5221030|refseq:NP_003202.3|dip:DIP-32709N	refseq:NP_000917.3|refseq:NP_001189403.1|refseq:NP_001258090.1|refseq:NP_001258091.1	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/09/13	rogid:LPhuo6buYUphV9aJ456Ydq36fnU9606	-	-	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P03372	ensembl:ENSG00000082175	intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7	intact:EBI-17173825	psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym)	uniprotkb:PGR(gene name)|psi-mi:PGR(display_short)|uniprotkb:NR3C3(gene name synonym)|ensembl:prgr_human_gene(shortlabel)|psi-mi:ENSG00000082175(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Lucey et al. (2004)	pubmed:16282588|imex:IM-26384	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20738697|imex:IM-26384-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB	refseq:NP_000917.3|refseq:NP_001189403.1|refseq:NP_001258090.1|refseq:NP_001258091.1	-	-	-	figure legend:Fig. 1C|comment:Control ChIP/re-ChIP were also performed, using isotype-matched mouse immunoglobulins for the first IP. On re-IP  with ER-alpha as a bait, pS2 was immunoprecipitated from the supernatants and not from the eluted primary immunoprecipitates.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2018/04/13	2018/09/13	rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606	-	-	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)