#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q86VZ6 uniprotkb:P49116 intact:EBI-11023753|uniprotkb:Q8N3L7|uniprotkb:A4D195|ensembl:ENSP00000283928 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:jazf1_human(display_long)|uniprotkb:JAZF1(gene name)|psi-mi:JAZF1(display_short)|uniprotkb:TAK1-interacting protein 27(gene name synonym)|uniprotkb:TIP27(gene name synonym)|uniprotkb:ZNF802(gene name synonym)|uniprotkb:Zinc finger protein 802(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nakajima et al. (2003) imex:IM-26489|pubmed:15302918 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20650836|imex:IM-26489-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778231.2|ensembl:ENSG00000153814(gene)|ensembl:ENST00000283928(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030436|interpro:IPR036236 refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N - - - figure legend:na|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/24 2018/07/25 rogid:vMCocmTjETz23vpigEMmoBJERcY9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 rigid:vfI7+T4E/gLXqkDpPlYLdR0e360 false - sufficient binding region:190..190-596..596 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86VZ6 uniprotkb:P49116 intact:EBI-11023753|uniprotkb:Q8N3L7|uniprotkb:A4D195|ensembl:ENSP00000283928 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:jazf1_human(display_long)|uniprotkb:JAZF1(gene name)|psi-mi:JAZF1(display_short)|uniprotkb:TAK1-interacting protein 27(gene name synonym)|uniprotkb:TIP27(gene name synonym)|uniprotkb:ZNF802(gene name synonym)|uniprotkb:Zinc finger protein 802(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0728"(gal4 vp16 complementation) Nakajima et al. (2003) imex:IM-26489|pubmed:15302918 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20650881|imex:IM-26489-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778231.2|ensembl:ENSG00000153814(gene)|ensembl:ENST00000283928(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030436|interpro:IPR036236 refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N - - - figure legend:Fig. 3, 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cv-1)|taxid:9534(Monkey African Green kidney fibroblast) - 2018/07/24 2018/09/11 rogid:vMCocmTjETz23vpigEMmoBJERcY9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 rigid:vfI7+T4E/gLXqkDpPlYLdR0e360 false - necessary binding region:362-450|mutation decreasing interaction strength:576-576 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86VZ6 uniprotkb:P49116 intact:EBI-11023753|uniprotkb:Q8N3L7|uniprotkb:A4D195|ensembl:ENSP00000283928 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:jazf1_human(display_long)|uniprotkb:JAZF1(gene name)|psi-mi:JAZF1(display_short)|uniprotkb:TAK1-interacting protein 27(gene name synonym)|uniprotkb:TIP27(gene name synonym)|uniprotkb:ZNF802(gene name synonym)|uniprotkb:Zinc finger protein 802(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0728"(gal4 vp16 complementation) Nakajima et al. (2003) imex:IM-26489|pubmed:15302918 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20650936|imex:IM-26489-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778231.2|ensembl:ENSG00000153814(gene)|ensembl:ENST00000283928(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030436|interpro:IPR036236 refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cv-1)|taxid:9534(Monkey African Green kidney fibroblast) - 2018/07/24 2018/07/25 rogid:vMCocmTjETz23vpigEMmoBJERcY9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 rigid:vfI7+T4E/gLXqkDpPlYLdR0e360 false necessary binding region:40-58|sufficient binding region:39-79|mutation with no effect:47-47|mutation disrupting interaction strength:60-60|mutation decreasing interaction strength:76-76|mutation with no effect:69-69 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86VZ6 uniprotkb:P49116 intact:EBI-11023753|uniprotkb:Q8N3L7|uniprotkb:A4D195|ensembl:ENSP00000283928 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:jazf1_human(display_long)|uniprotkb:JAZF1(gene name)|psi-mi:JAZF1(display_short)|uniprotkb:TAK1-interacting protein 27(gene name synonym)|uniprotkb:TIP27(gene name synonym)|uniprotkb:ZNF802(gene name synonym)|uniprotkb:Zinc finger protein 802(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0096"(pull down) Nakajima et al. (2003) imex:IM-26489|pubmed:15302918 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20709632|imex:IM-26489-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778231.2|ensembl:ENSG00000153814(gene)|ensembl:ENST00000283928(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030436|interpro:IPR036236 refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N - - - figure legend:Figs. 6B, 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/24 2018/07/26 rogid:vMCocmTjETz23vpigEMmoBJERcY9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 rigid:vfI7+T4E/gLXqkDpPlYLdR0e360 false glutathione s tranferase tag:n-n|sufficient binding region:39-101|necessary binding region:39-79 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q86VZ6 uniprotkb:P49116 intact:EBI-11023753|uniprotkb:Q8N3L7|uniprotkb:A4D195|ensembl:ENSP00000283928 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:jazf1_human(display_long)|uniprotkb:JAZF1(gene name)|psi-mi:JAZF1(display_short)|uniprotkb:TAK1-interacting protein 27(gene name synonym)|uniprotkb:TIP27(gene name synonym)|uniprotkb:ZNF802(gene name synonym)|uniprotkb:Zinc finger protein 802(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nakajima et al. (2003) imex:IM-26489|pubmed:15302918 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20709652|imex:IM-26489-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778231.2|ensembl:ENSG00000153814(gene)|ensembl:ENST00000283928(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030436|interpro:IPR036236 refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N - - - figure legend:Fig. 6D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2018/07/24 2018/07/26 rogid:vMCocmTjETz23vpigEMmoBJERcY9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 rigid:vfI7+T4E/gLXqkDpPlYLdR0e360 false myc tag:?-?|necessary binding region:39-79 flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86VZ6 uniprotkb:P49116 intact:EBI-11023753|uniprotkb:Q8N3L7|uniprotkb:A4D195|ensembl:ENSP00000283928 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:jazf1_human(display_long)|uniprotkb:JAZF1(gene name)|psi-mi:JAZF1(display_short)|uniprotkb:TAK1-interacting protein 27(gene name synonym)|uniprotkb:TIP27(gene name synonym)|uniprotkb:ZNF802(gene name synonym)|uniprotkb:Zinc finger protein 802(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Nakajima et al. (2003) imex:IM-26489|pubmed:15302918 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-20709672|imex:IM-26489-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778231.2|ensembl:ENSG00000153814(gene)|ensembl:ENST00000283928(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030436|interpro:IPR036236 refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N go:"GO:0005634"(nucleus) - - figure legend:Fig. 7D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2018/07/24 2018/07/26 rogid:vMCocmTjETz23vpigEMmoBJERcY9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 rigid:vfI7+T4E/gLXqkDpPlYLdR0e360 false green fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0707"(anti tag immunostaining)