#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q86WQ0 uniprotkb:P49116-2 intact:EBI-10260040|uniprotkb:B4DW92|uniprotkb:A6NGP7|ensembl:ENSP00000332823 intact:EBI-20709881|ensembl:ENSP00000320447|ensembl:ENSP00000483059 psi-mi:nr2ca_human(display_long)|uniprotkb:NR2C2AP(gene name)|psi-mi:NR2C2AP(display_short)|uniprotkb:TR4 orphan receptor-associated 16 kDa protein(gene name synonym)|uniprotkb:TRA16(gene name synonym) psi-mi:p49116-2(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym) psi-mi:"MI:0232"(transcriptional complementation assay) Yang et al. (2003) imex:IM-26651|pubmed:12486131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20709792|imex:IM-26651-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287874.1|refseq:NP_795361.1|ensembl:ENSG00000184162(gene)|ensembl:ENST00000331552(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-383280 ensembl:ENSG00000177463(gene)|ensembl:ENST00000323373(transcript)|ensembl:ENST00000617312(transcript)|intact:EBI-2652582(isoform-parent)|uniprotkb:P49116-2(isoform-parent) - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2018/07/24 2018/07/27 rogid:qRHzm919kmXqd6BJv1fCAjoLj7Y9606 rogid:t22p9J2g2J9jawQv0AKrSLsa7Qo9606 rigid:NEdnvZJU7L0pPCyntiXLuLS3AyQ false tag:?-? tag:?-? - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86WQ0 uniprotkb:P49116 intact:EBI-10260040|uniprotkb:B4DW92|uniprotkb:A6NGP7|ensembl:ENSP00000332823 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:nr2ca_human(display_long)|uniprotkb:NR2C2AP(gene name)|psi-mi:NR2C2AP(display_short)|uniprotkb:TR4 orphan receptor-associated 16 kDa protein(gene name synonym)|uniprotkb:TRA16(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Yang et al. (2003) imex:IM-26651|pubmed:12486131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-20709806|imex:IM-26651-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287874.1|refseq:NP_795361.1|ensembl:ENSG00000184162(gene)|ensembl:ENST00000331552(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-383280 refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N go:"GO:0031965"(nuclear membrane) - - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma) - 2018/07/24 2018/07/27 rogid:qRHzm919kmXqd6BJv1fCAjoLj7Y9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 rigid:zCCmf0BVmREPFkteUvryilp7JEo false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q86WQ0 uniprotkb:P49116-2 intact:EBI-10260040|uniprotkb:B4DW92|uniprotkb:A6NGP7|ensembl:ENSP00000332823 intact:EBI-20709881|ensembl:ENSP00000320447|ensembl:ENSP00000483059 psi-mi:nr2ca_human(display_long)|uniprotkb:NR2C2AP(gene name)|psi-mi:NR2C2AP(display_short)|uniprotkb:TR4 orphan receptor-associated 16 kDa protein(gene name synonym)|uniprotkb:TRA16(gene name synonym) psi-mi:p49116-2(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yang et al. (2003) imex:IM-26651|pubmed:12486131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20709822|imex:IM-26651-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287874.1|refseq:NP_795361.1|ensembl:ENSG00000184162(gene)|ensembl:ENST00000331552(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-383280 ensembl:ENSG00000177463(gene)|ensembl:ENST00000323373(transcript)|ensembl:ENST00000617312(transcript)|intact:EBI-2652582(isoform-parent)|uniprotkb:P49116-2(isoform-parent) go:"GO:0031965"(nuclear membrane) - - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2018/07/24 2018/07/27 rogid:qRHzm919kmXqd6BJv1fCAjoLj7Y9606 rogid:t22p9J2g2J9jawQv0AKrSLsa7Qo9606 rigid:NEdnvZJU7L0pPCyntiXLuLS3AyQ false gal4 dna binding domain:?-? vp16 activation domain:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49116-2 uniprotkb:P49116-2 intact:EBI-20709881|ensembl:ENSP00000320447|ensembl:ENSP00000483059 intact:EBI-20709881|ensembl:ENSP00000320447|ensembl:ENSP00000483059 psi-mi:p49116-2(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym) psi-mi:p49116-2(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yang et al. (2003) imex:IM-26651|pubmed:12486131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20709869|imex:IM-26651-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177463(gene)|ensembl:ENST00000323373(transcript)|ensembl:ENST00000617312(transcript)|intact:EBI-2652582(isoform-parent)|uniprotkb:P49116-2(isoform-parent) ensembl:ENSG00000177463(gene)|ensembl:ENST00000323373(transcript)|ensembl:ENST00000617312(transcript)|intact:EBI-2652582(isoform-parent)|uniprotkb:P49116-2(isoform-parent) go:"GO:0031965"(nuclear membrane) - - figure legend:Fig. 9A, 9B|comment:"The addition of NR2C2AP (Q86WQ0) suppressed the interaction between TR4 and TR4-LBD"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2018/07/24 2018/07/27 rogid:t22p9J2g2J9jawQv0AKrSLsa7Qo9606 rogid:t22p9J2g2J9jawQv0AKrSLsa7Qo9606 rigid:Q38WduoQeaf7cRov9Wt4MTw7Hiw false gal4 dna binding domain:?-?|sufficient binding region:224-615 sufficient binding region:125-615|vp16 activation domain:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49116-2 uniprotkb:P49116-2 intact:EBI-20709881|ensembl:ENSP00000320447|ensembl:ENSP00000483059 intact:EBI-20709881|ensembl:ENSP00000320447|ensembl:ENSP00000483059 psi-mi:p49116-2(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym) psi-mi:p49116-2(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yang et al. (2003) imex:IM-26651|pubmed:12486131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20715053|imex:IM-26651-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177463(gene)|ensembl:ENST00000323373(transcript)|ensembl:ENST00000617312(transcript)|intact:EBI-2652582(isoform-parent)|uniprotkb:P49116-2(isoform-parent) ensembl:ENSG00000177463(gene)|ensembl:ENST00000323373(transcript)|ensembl:ENST00000617312(transcript)|intact:EBI-2652582(isoform-parent)|uniprotkb:P49116-2(isoform-parent) go:"GO:0031965"(nuclear membrane) - - figure legend:Fig. 9A|comment:"The addition of NR2C2AP (Q86WQ0) suppressed the interaction between TR4 and TR4-LBD"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2018/07/24 2018/08/02 rogid:t22p9J2g2J9jawQv0AKrSLsa7Qo9606 rogid:t22p9J2g2J9jawQv0AKrSLsa7Qo9606 rigid:NEdnvZJU7L0pPCyntiXLuLS3AyQ false gal4 dna binding domain:?-?|sufficient binding region:224-615 vp16 activation domain:?-?|sufficient binding region:125-615 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49116-2 uniprotkb:Q86WQ0 intact:EBI-20709881|ensembl:ENSP00000320447|ensembl:ENSP00000483059 intact:EBI-10260040|uniprotkb:B4DW92|uniprotkb:A6NGP7|ensembl:ENSP00000332823 psi-mi:p49116-2(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym) psi-mi:nr2ca_human(display_long)|uniprotkb:NR2C2AP(gene name)|psi-mi:NR2C2AP(display_short)|uniprotkb:TR4 orphan receptor-associated 16 kDa protein(gene name synonym)|uniprotkb:TRA16(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yang et al. (2003) imex:IM-26651|pubmed:12486131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20715053|imex:IM-26651-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000177463(gene)|ensembl:ENST00000323373(transcript)|ensembl:ENST00000617312(transcript)|intact:EBI-2652582(isoform-parent)|uniprotkb:P49116-2(isoform-parent) refseq:NP_001287874.1|refseq:NP_795361.1|ensembl:ENSG00000184162(gene)|ensembl:ENST00000331552(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-383280 go:"GO:0031965"(nuclear membrane) - - figure legend:Fig. 9A|comment:"The addition of NR2C2AP (Q86WQ0) suppressed the interaction between TR4 and TR4-LBD"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2018/07/24 2018/08/02 rogid:t22p9J2g2J9jawQv0AKrSLsa7Qo9606 rogid:qRHzm919kmXqd6BJv1fCAjoLj7Y9606 rigid:NEdnvZJU7L0pPCyntiXLuLS3AyQ false gal4 dna binding domain:?-?|sufficient binding region:224-615 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q86WQ0 uniprotkb:P49116-2 intact:EBI-10260040|uniprotkb:B4DW92|uniprotkb:A6NGP7|ensembl:ENSP00000332823 intact:EBI-20709881|ensembl:ENSP00000320447|ensembl:ENSP00000483059 psi-mi:nr2ca_human(display_long)|uniprotkb:NR2C2AP(gene name)|psi-mi:NR2C2AP(display_short)|uniprotkb:TR4 orphan receptor-associated 16 kDa protein(gene name synonym)|uniprotkb:TRA16(gene name synonym) psi-mi:p49116-2(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yang et al. (2003) imex:IM-26651|pubmed:12486131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20709838|imex:IM-26651-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287874.1|refseq:NP_795361.1|ensembl:ENSG00000184162(gene)|ensembl:ENST00000331552(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-383280 ensembl:ENSG00000177463(gene)|ensembl:ENST00000323373(transcript)|ensembl:ENST00000617312(transcript)|intact:EBI-2652582(isoform-parent)|uniprotkb:P49116-2(isoform-parent) go:"GO:0031965"(nuclear membrane) - - figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/24 2018/07/27 rogid:qRHzm919kmXqd6BJv1fCAjoLj7Y9606 rogid:t22p9J2g2J9jawQv0AKrSLsa7Qo9606 rigid:NEdnvZJU7L0pPCyntiXLuLS3AyQ false his tag:?-?|35s radiolabel:?-? 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q86WQ0 uniprotkb:P49116 intact:EBI-10260040|uniprotkb:B4DW92|uniprotkb:A6NGP7|ensembl:ENSP00000332823 intact:EBI-2652582|uniprotkb:A8K3H5|uniprotkb:P55092|uniprotkb:B6ZGT8|ensembl:ENSP00000376814|ensembl:ENSP00000384463|ensembl:ENSP00000388387 psi-mi:nr2ca_human(display_long)|uniprotkb:NR2C2AP(gene name)|psi-mi:NR2C2AP(display_short)|uniprotkb:TR4 orphan receptor-associated 16 kDa protein(gene name synonym)|uniprotkb:TRA16(gene name synonym) psi-mi:nr2c2_human(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yang et al. (2003) imex:IM-26651|pubmed:12486131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20709860|imex:IM-26651-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287874.1|refseq:NP_795361.1|ensembl:ENSG00000184162(gene)|ensembl:ENST00000331552(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-383280 refseq:NP_003289.2|refseq:NP_001278623.1|ensembl:ENSG00000177463(gene)|ensembl:ENST00000393102(transcript)|ensembl:ENST00000406272(transcript)|ensembl:ENST00000425241(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P49116|rcsb pdb:3P0U|reactome:R-HSA-383280|refseq:XP_016862609.1|dip:DIP-5999N go:"GO:0031965"(nuclear membrane) - - figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-h1299)|taxid:9606(Homo sapiens lung lymph node carcinoma) - 2018/07/24 2018/07/27 rogid:qRHzm919kmXqd6BJv1fCAjoLj7Y9606 rogid:FQqhbuxItvCQ2iu5nydvHZaNog89606 rigid:zCCmf0BVmREPFkteUvryilp7JEo false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q86WQ0 uniprotkb:P49116-2 intact:EBI-10260040|uniprotkb:B4DW92|uniprotkb:A6NGP7|ensembl:ENSP00000332823 intact:EBI-20709881|ensembl:ENSP00000320447|ensembl:ENSP00000483059 psi-mi:nr2ca_human(display_long)|uniprotkb:NR2C2AP(gene name)|psi-mi:NR2C2AP(display_short)|uniprotkb:TR4 orphan receptor-associated 16 kDa protein(gene name synonym)|uniprotkb:TRA16(gene name synonym) psi-mi:p49116-2(display_long)|uniprotkb:NR2C2(gene name)|psi-mi:NR2C2(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:TR4(gene name synonym)|uniprotkb:Orphan nuclear receptor TAK1(gene name synonym)|uniprotkb:Orphan nuclear receptor TR4(gene name synonym)|uniprotkb:Testicular receptor 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2003) imex:IM-26651|pubmed:12486131 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-20715074|imex:IM-26651-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287874.1|refseq:NP_795361.1|ensembl:ENSG00000184162(gene)|ensembl:ENST00000331552(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-383280 ensembl:ENSG00000177463(gene)|ensembl:ENST00000323373(transcript)|ensembl:ENST00000617312(transcript)|intact:EBI-2652582(isoform-parent)|uniprotkb:P49116-2(isoform-parent) - - - figure legend:Fig. 9C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2018/07/24 2018/08/02 rogid:qRHzm919kmXqd6BJv1fCAjoLj7Y9606 rogid:t22p9J2g2J9jawQv0AKrSLsa7Qo9606 rigid:NEdnvZJU7L0pPCyntiXLuLS3AyQ false 35s radiolabel:?-? 35s radiolabel:?-?|sufficient binding region:125-615 - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)