#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P26006	uniprotkb:P48509	intact:EBI-2550768|uniprotkb:B7ZM80|ensembl:ENSP00000315190|uniprotkb:A7E246|uniprotkb:B9EGQ1|uniprotkb:D3DTX4|uniprotkb:D3DTX5	intact:EBI-10210332|uniprotkb:Q86U54|uniprotkb:Q14826|uniprotkb:E9PI15|uniprotkb:Q96TE3|uniprotkb:A8KAK8|ensembl:ENSP00000324101|ensembl:ENSP00000380565|ensembl:ENSP00000380566|ensembl:ENSP00000432385	psi-mi:ita3_human(display_long)|uniprotkb:ITGA3(gene name)|psi-mi:ITGA3(display_short)|uniprotkb:MSK18(gene name synonym)|uniprotkb:Galactoprotein B3(gene name synonym)|uniprotkb:VLA-3 subunit alpha(gene name synonym)|uniprotkb:FRP-2(gene name synonym)|uniprotkb:CD49 antigen-like family member C(gene name synonym)	psi-mi:cd151_human(display_long)|uniprotkb:CD151(gene name)|psi-mi:CD151(display_short)|uniprotkb:GP27(gene name synonym)|uniprotkb:Membrane glycoprotein SFA-1(gene name synonym)|uniprotkb:Platelet-endothelial tetraspan antigen 3(gene name synonym)|uniprotkb:TSPAN24(gene name synonym)|uniprotkb:Tetraspanin-24(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sterk et al. (2000)	imex:IM-26297|pubmed:10811835	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16763007|imex:IM-26297-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042493"|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072006"(nephron development)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097205"(renal filtration)|go:"GO:0035640"(exploration behavior)|go:"GO:1990812"(growth cone filopodium)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|mint:P26006|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-8874081|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|ensembl:ENSG00000005884(gene)|ensembl:ENST00000320031(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007613"(memory)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030324"(lung development)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034698"(response to gonadotropin)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|refseq:NP_002195.1|dip:DIP-140N	refseq:NP_001034579.1|refseq:NP_004348.2|refseq:NP_620598.1|refseq:NP_620599.1|ensembl:ENSG00000177697(gene)|ensembl:ENST00000322008(transcript)|ensembl:ENST00000397420(transcript)|ensembl:ENST00000397421(transcript)|ensembl:ENST00000530726(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0042098"(T cell proliferation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P48509|reactome:R-HSA-2022090|reactome:R-HSA-446107	-	-	-	figure legend:Fig.3|comment:K562 cells stably expressing α3β1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2018/02/08	2018/02/08	rogid:gmrsTA4D01ARM8U0n7b2HBjo9vs9606	rogid:Cxlf8123VFoYdzJ5fh0jzkSaaL09606	rigid:CrYRTFhIY3Vlled9q/cKfWyPAXs	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23229	uniprotkb:P48509	intact:EBI-2436548|uniprotkb:Q9UCT1|uniprotkb:B2RMU9|uniprotkb:B4DG69|uniprotkb:B4DKB8|uniprotkb:Q08443|uniprotkb:Q0MRC7|uniprotkb:Q14646|uniprotkb:Q16508|uniprotkb:Q53RX7|uniprotkb:Q59HB7|uniprotkb:Q86VL6|uniprotkb:Q9UN03|uniprotkb:G5E9H1|uniprotkb:C4AM96|ensembl:ENSP00000406694	intact:EBI-10210332|uniprotkb:Q86U54|uniprotkb:Q14826|uniprotkb:E9PI15|uniprotkb:Q96TE3|uniprotkb:A8KAK8|ensembl:ENSP00000324101|ensembl:ENSP00000380565|ensembl:ENSP00000380566|ensembl:ENSP00000432385	psi-mi:ita6_human(display_long)|uniprotkb:ITGA6(gene name)|psi-mi:ITGA6(display_short)|uniprotkb:VLA-6(gene name synonym)|uniprotkb:CD49 antigen-like family member F(gene name synonym)	psi-mi:cd151_human(display_long)|uniprotkb:CD151(gene name)|psi-mi:CD151(display_short)|uniprotkb:GP27(gene name synonym)|uniprotkb:Membrane glycoprotein SFA-1(gene name synonym)|uniprotkb:Platelet-endothelial tetraspan antigen 3(gene name synonym)|uniprotkb:TSPAN24(gene name synonym)|uniprotkb:Tetraspanin-24(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sterk et al. (2000)	imex:IM-26297|pubmed:10811835	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16763013|imex:IM-26297-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000201.2|refseq:NP_001073286.1|refseq:NP_001303235.1|ensembl:ENSG00000091409(gene)|ensembl:ENST00000442250(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0034676"(integrin alpha6-beta4 complex)|go:"GO:0035878"(nail development)|go:"GO:0038132"(neuregulin binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR032695|mint:P23229|rcsb pdb:7CEB|rcsb pdb:7CEC|reactome:R-HSA-2022090|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107	refseq:NP_001034579.1|refseq:NP_004348.2|refseq:NP_620598.1|refseq:NP_620599.1|ensembl:ENSG00000177697(gene)|ensembl:ENST00000322008(transcript)|ensembl:ENST00000397420(transcript)|ensembl:ENST00000397421(transcript)|ensembl:ENST00000530726(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0042098"(T cell proliferation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P48509|reactome:R-HSA-2022090|reactome:R-HSA-446107	-	-	-	figure legend:Fig.3|comment:K562 cells stably expressing α6β4.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2018/02/08	2018/02/08	rogid:YyoW/gnP6QH8w7M9UxzVxMTkpOg9606	rogid:Cxlf8123VFoYdzJ5fh0jzkSaaL09606	rigid:zDIpBV5dvWfiWHpALCTI0d8E3To	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P16144	uniprotkb:P48509	intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97	intact:EBI-10210332|uniprotkb:Q86U54|uniprotkb:Q14826|uniprotkb:E9PI15|uniprotkb:Q96TE3|uniprotkb:A8KAK8|ensembl:ENSP00000324101|ensembl:ENSP00000380565|ensembl:ENSP00000380566|ensembl:ENSP00000432385	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	psi-mi:cd151_human(display_long)|uniprotkb:CD151(gene name)|psi-mi:CD151(display_short)|uniprotkb:GP27(gene name synonym)|uniprotkb:Membrane glycoprotein SFA-1(gene name synonym)|uniprotkb:Platelet-endothelial tetraspan antigen 3(gene name synonym)|uniprotkb:TSPAN24(gene name synonym)|uniprotkb:Tetraspanin-24(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Sterk et al. (2000)	imex:IM-26297|pubmed:10811835	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16763018|imex:IM-26297-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1	refseq:NP_001034579.1|refseq:NP_004348.2|refseq:NP_620598.1|refseq:NP_620599.1|ensembl:ENSG00000177697(gene)|ensembl:ENST00000322008(transcript)|ensembl:ENST00000397420(transcript)|ensembl:ENST00000397421(transcript)|ensembl:ENST00000530726(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0042098"(T cell proliferation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P48509|reactome:R-HSA-2022090|reactome:R-HSA-446107	-	-	-	figure legend:Fig.3|comment:K562 cells stably expressing α6β4.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2018/02/08	2018/02/08	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	rogid:Cxlf8123VFoYdzJ5fh0jzkSaaL09606	rigid:cCAk4t3bGqYuagqaiomoToKAeS8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P26006	uniprotkb:P48509	intact:EBI-2550768|uniprotkb:B7ZM80|ensembl:ENSP00000315190|uniprotkb:A7E246|uniprotkb:B9EGQ1|uniprotkb:D3DTX4|uniprotkb:D3DTX5	intact:EBI-10210332|uniprotkb:Q86U54|uniprotkb:Q14826|uniprotkb:E9PI15|uniprotkb:Q96TE3|uniprotkb:A8KAK8|ensembl:ENSP00000324101|ensembl:ENSP00000380565|ensembl:ENSP00000380566|ensembl:ENSP00000432385	psi-mi:ita3_human(display_long)|uniprotkb:ITGA3(gene name)|psi-mi:ITGA3(display_short)|uniprotkb:MSK18(gene name synonym)|uniprotkb:Galactoprotein B3(gene name synonym)|uniprotkb:VLA-3 subunit alpha(gene name synonym)|uniprotkb:FRP-2(gene name synonym)|uniprotkb:CD49 antigen-like family member C(gene name synonym)	psi-mi:cd151_human(display_long)|uniprotkb:CD151(gene name)|psi-mi:CD151(display_short)|uniprotkb:GP27(gene name synonym)|uniprotkb:Membrane glycoprotein SFA-1(gene name synonym)|uniprotkb:Platelet-endothelial tetraspan antigen 3(gene name synonym)|uniprotkb:TSPAN24(gene name synonym)|uniprotkb:Tetraspanin-24(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Sterk et al. (2000)	imex:IM-26297|pubmed:10811835	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16763038|imex:IM-26297-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042493"|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072006"(nephron development)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097205"(renal filtration)|go:"GO:0035640"(exploration behavior)|go:"GO:1990812"(growth cone filopodium)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|mint:P26006|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-8874081|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|ensembl:ENSG00000005884(gene)|ensembl:ENST00000320031(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007613"(memory)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030324"(lung development)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034698"(response to gonadotropin)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|refseq:NP_002195.1|dip:DIP-140N	refseq:NP_001034579.1|refseq:NP_004348.2|refseq:NP_620598.1|refseq:NP_620599.1|ensembl:ENSG00000177697(gene)|ensembl:ENST00000322008(transcript)|ensembl:ENST00000397420(transcript)|ensembl:ENST00000397421(transcript)|ensembl:ENST00000530726(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0042098"(T cell proliferation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P48509|reactome:R-HSA-2022090|reactome:R-HSA-446107	go:"GO:0045178"(basal part of cell)	-	-	figure legend:Fig.4A-C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-keratinocyte)|taxid:9606(Homo sapiens)	-	2018/02/08	2018/02/08	rogid:gmrsTA4D01ARM8U0n7b2HBjo9vs9606	rogid:Cxlf8123VFoYdzJ5fh0jzkSaaL09606	rigid:CrYRTFhIY3Vlled9q/cKfWyPAXs	false	-	-	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:P16144	uniprotkb:P48509	intact:EBI-948678|ensembl:ENSP00000200181|uniprotkb:O14690|uniprotkb:O14691|uniprotkb:O15339|uniprotkb:O15340|uniprotkb:O15341|uniprotkb:Q9UIQ4|uniprotkb:A0AVL6|uniprotkb:Q0VF97	intact:EBI-10210332|uniprotkb:Q86U54|uniprotkb:Q14826|uniprotkb:E9PI15|uniprotkb:Q96TE3|uniprotkb:A8KAK8|ensembl:ENSP00000324101|ensembl:ENSP00000380565|ensembl:ENSP00000380566|ensembl:ENSP00000432385	psi-mi:itb4_human(display_long)|uniprotkb:GP150(gene name synonym)|uniprotkb:ITGB4(gene name)|psi-mi:ITGB4(display_short)	psi-mi:cd151_human(display_long)|uniprotkb:CD151(gene name)|psi-mi:CD151(display_short)|uniprotkb:GP27(gene name synonym)|uniprotkb:Membrane glycoprotein SFA-1(gene name synonym)|uniprotkb:Platelet-endothelial tetraspan antigen 3(gene name synonym)|uniprotkb:TSPAN24(gene name synonym)|uniprotkb:Tetraspanin-24(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Sterk et al. (2000)	imex:IM-26297|pubmed:10811835	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16763092|imex:IM-26297-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-40182N|ensembl:ENSG00000132470(gene)|ensembl:ENST00000200181(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031252"(cell leading edge)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035878"(nail development)|go:"GO:0043235"(receptor complex)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048870"(cell motility)|go:"GO:0061450"(trophoblast cell migration)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR012013(Integrin beta-4 subunit)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR033760|interpro:IPR036116|interpro:IPR036349|interpro:IPR036465|interpro:IPR038081|interpro:IPR040622|mint:P16144|rcsb pdb:1QG3|rcsb pdb:2YRZ|rcsb pdb:3F7P|rcsb pdb:3F7Q|rcsb pdb:3F7R|rcsb pdb:3FQ4|rcsb pdb:3FSO|rcsb pdb:3H6A|rcsb pdb:4Q58|rcsb pdb:4WTW|rcsb pdb:4WTX|rcsb pdb:6GVK|rcsb pdb:6GVL|reactome:R-HSA-2022090|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107|refseq:NP_000204.3|refseq:NP_001005619.1|refseq:NP_001005731.1|refseq:NP_001308052.1	refseq:NP_001034579.1|refseq:NP_004348.2|refseq:NP_620598.1|refseq:NP_620599.1|ensembl:ENSG00000177697(gene)|ensembl:ENST00000322008(transcript)|ensembl:ENST00000397420(transcript)|ensembl:ENST00000397421(transcript)|ensembl:ENST00000530726(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0042098"(T cell proliferation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P48509|reactome:R-HSA-2022090|reactome:R-HSA-446107	go:"GO:0030056"(hemidesmosome)	-	-	figure legend:Fig.4G-I, Fig. 5D-F, Fig7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-keratinocyte)|taxid:9606(Homo sapiens)	-	2018/02/08	2018/02/08	rogid:XSzTESyjef5LPBxsph8tWNGJ2u49606	rogid:Cxlf8123VFoYdzJ5fh0jzkSaaL09606	rigid:cCAk4t3bGqYuagqaiomoToKAeS8	false	-	-	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:P26006	uniprotkb:P48509	intact:EBI-2550768|uniprotkb:B7ZM80|ensembl:ENSP00000315190|uniprotkb:A7E246|uniprotkb:B9EGQ1|uniprotkb:D3DTX4|uniprotkb:D3DTX5	intact:EBI-10210332|uniprotkb:Q86U54|uniprotkb:Q14826|uniprotkb:E9PI15|uniprotkb:Q96TE3|uniprotkb:A8KAK8|ensembl:ENSP00000324101|ensembl:ENSP00000380565|ensembl:ENSP00000380566|ensembl:ENSP00000432385	psi-mi:ita3_human(display_long)|uniprotkb:ITGA3(gene name)|psi-mi:ITGA3(display_short)|uniprotkb:MSK18(gene name synonym)|uniprotkb:Galactoprotein B3(gene name synonym)|uniprotkb:VLA-3 subunit alpha(gene name synonym)|uniprotkb:FRP-2(gene name synonym)|uniprotkb:CD49 antigen-like family member C(gene name synonym)	psi-mi:cd151_human(display_long)|uniprotkb:CD151(gene name)|psi-mi:CD151(display_short)|uniprotkb:GP27(gene name synonym)|uniprotkb:Membrane glycoprotein SFA-1(gene name synonym)|uniprotkb:Platelet-endothelial tetraspan antigen 3(gene name synonym)|uniprotkb:TSPAN24(gene name synonym)|uniprotkb:Tetraspanin-24(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Sterk et al. (2000)	imex:IM-26297|pubmed:10811835	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16763153|imex:IM-26297-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042493"|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072006"(nephron development)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097205"(renal filtration)|go:"GO:0035640"(exploration behavior)|go:"GO:1990812"(growth cone filopodium)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|mint:P26006|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-8874081|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|ensembl:ENSG00000005884(gene)|ensembl:ENST00000320031(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007613"(memory)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030324"(lung development)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034698"(response to gonadotropin)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|refseq:NP_002195.1|dip:DIP-140N	refseq:NP_001034579.1|refseq:NP_004348.2|refseq:NP_620598.1|refseq:NP_620599.1|ensembl:ENSG00000177697(gene)|ensembl:ENST00000322008(transcript)|ensembl:ENST00000397420(transcript)|ensembl:ENST00000397421(transcript)|ensembl:ENST00000530726(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0042098"(T cell proliferation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P48509|reactome:R-HSA-2022090|reactome:R-HSA-446107	go:"GO:0030056"(hemidesmosome)	-	-	figure legend:Fig.5G-I, Fig7F|comment:weak colocalization|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-keratinocyte)|taxid:9606(Homo sapiens)	-	2018/02/08	2018/02/08	rogid:gmrsTA4D01ARM8U0n7b2HBjo9vs9606	rogid:Cxlf8123VFoYdzJ5fh0jzkSaaL09606	rigid:CrYRTFhIY3Vlled9q/cKfWyPAXs	false	-	-	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)
uniprotkb:P23229	uniprotkb:P48509	intact:EBI-2436548|uniprotkb:Q9UCT1|uniprotkb:B2RMU9|uniprotkb:B4DG69|uniprotkb:B4DKB8|uniprotkb:Q08443|uniprotkb:Q0MRC7|uniprotkb:Q14646|uniprotkb:Q16508|uniprotkb:Q53RX7|uniprotkb:Q59HB7|uniprotkb:Q86VL6|uniprotkb:Q9UN03|uniprotkb:G5E9H1|uniprotkb:C4AM96|ensembl:ENSP00000406694	intact:EBI-10210332|uniprotkb:Q86U54|uniprotkb:Q14826|uniprotkb:E9PI15|uniprotkb:Q96TE3|uniprotkb:A8KAK8|ensembl:ENSP00000324101|ensembl:ENSP00000380565|ensembl:ENSP00000380566|ensembl:ENSP00000432385	psi-mi:ita6_human(display_long)|uniprotkb:ITGA6(gene name)|psi-mi:ITGA6(display_short)|uniprotkb:VLA-6(gene name synonym)|uniprotkb:CD49 antigen-like family member F(gene name synonym)	psi-mi:cd151_human(display_long)|uniprotkb:CD151(gene name)|psi-mi:CD151(display_short)|uniprotkb:GP27(gene name synonym)|uniprotkb:Membrane glycoprotein SFA-1(gene name synonym)|uniprotkb:Platelet-endothelial tetraspan antigen 3(gene name synonym)|uniprotkb:TSPAN24(gene name synonym)|uniprotkb:Tetraspanin-24(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Sterk et al. (2000)	imex:IM-26297|pubmed:10811835	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16763206|imex:IM-26297-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000201.2|refseq:NP_001073286.1|refseq:NP_001303235.1|ensembl:ENSG00000091409(gene)|ensembl:ENST00000442250(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0034676"(integrin alpha6-beta4 complex)|go:"GO:0035878"(nail development)|go:"GO:0038132"(neuregulin binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR032695|mint:P23229|rcsb pdb:7CEB|rcsb pdb:7CEC|reactome:R-HSA-2022090|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107	refseq:NP_001034579.1|refseq:NP_004348.2|refseq:NP_620598.1|refseq:NP_620599.1|ensembl:ENSG00000177697(gene)|ensembl:ENST00000322008(transcript)|ensembl:ENST00000397420(transcript)|ensembl:ENST00000397421(transcript)|ensembl:ENST00000530726(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0042098"(T cell proliferation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045807"(positive regulation of endocytosis)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P48509|reactome:R-HSA-2022090|reactome:R-HSA-446107	go:"GO:0005925"(focal adhesion)	-	-	figure legend:Fig.5C|comment:weak interaction|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-keratinocyte)|taxid:9606(Homo sapiens)	-	2018/02/08	2018/07/11	rogid:YyoW/gnP6QH8w7M9UxzVxMTkpOg9606	rogid:Cxlf8123VFoYdzJ5fh0jzkSaaL09606	rigid:zDIpBV5dvWfiWHpALCTI0d8E3To	false	-	-	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)