#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P01887 uniprotkb:P11609 intact:EBI-1026566|ensembl:ENSMUSP00000099534|uniprotkb:Q91XJ8 intact:EBI-1026535|uniprotkb:Q91XK9 psi-mi:b2mg_mouse(display_long)|uniprotkb:B2m(gene name)|psi-mi:B2m(display_short) psi-mi:cd1d1_mouse(display_long)|uniprotkb:Cd1d1(gene name)|psi-mi:Cd1d1(display_short)|uniprotkb:Cd1.1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zeng et al. (1997) pubmed:9219685|doi:10.1126/science.277.5324.339|imex:IM-25233 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16213091|imex:IM-25233-1|dip:DIP-10999E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000060802(gene)|ensembl:ENSMUST00000102476(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006968"(cellular defense response)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|rcsb pdb:3BUY|rcsb pdb:3C8K|rcsb pdb:3CC5|rcsb pdb:3CCH|rcsb pdb:3CH1|rcsb pdb:3CPL|rcsb pdb:3CVH|rcsb pdb:3DMM|rcsb pdb:3E6F|rcsb pdb:3E6H|rcsb pdb:3ECB|rcsb pdb:3FOL|rcsb pdb:3FOM|rcsb pdb:3FON|rcsb pdb:3FTG|rcsb pdb:3G08|rcsb pdb:3GML|rcsb pdb:3GMM|rcsb pdb:3GMN|rcsb pdb:3GMO|rcsb pdb:3GMP|rcsb pdb:3GMQ|rcsb pdb:3GMR|rcsb pdb:3HE6|rcsb pdb:3HE7|rcsb pdb:3ILP|rcsb pdb:3ILQ|rcsb pdb:3L3H|rcsb pdb:3MA7|rcsb pdb:3NWM|rcsb pdb:3O8X|rcsb pdb:3O9W|rcsb pdb:3P4M|rcsb pdb:3P4N|rcsb pdb:3P4O|rcsb pdb:3P9L|rcsb pdb:3P9M|rcsb pdb:3PAB|rcsb pdb:3PQY|rcsb pdb:3PWU|rcsb pdb:3QI9|rcsb pdb:3QUK|rcsb pdb:3QUL|rcsb pdb:3QUX|rcsb pdb:3QUY|rcsb pdb:3QUZ|rcsb pdb:3RGV|rcsb pdb:3ROL|rcsb pdb:3ROO|rcsb pdb:3RTQ|rcsb pdb:3RUG|rcsb pdb:3RZC|rcsb pdb:3SCM|rcsb pdb:3SDA|rcsb pdb:3SDC|rcsb pdb:3SDD|rcsb pdb:3T1F|rcsb pdb:3TA3|rcsb pdb:3TBS|rcsb pdb:3TBT|rcsb pdb:3TBV|rcsb pdb:3TBW|rcsb pdb:3TBY|rcsb pdb:3TN0|rcsb pdb:3TO4|rcsb pdb:3TVM|rcsb pdb:3UBX|rcsb pdb:3VJ6|rcsb pdb:3WS3|rcsb pdb:3WS6|rcsb pdb:4APQ|rcsb pdb:4EI5|rcsb pdb:4ELM|rcsb pdb:4HS3|rcsb pdb:4HUU|rcsb pdb:4HUV|rcsb pdb:4HUW|rcsb pdb:4HUX|rcsb pdb:4HV8|rcsb pdb:4IHO|rcsb pdb:4IRJ|rcsb pdb:4IRS|rcsb pdb:4L8B|rcsb pdb:4L8C|rcsb pdb:4L8D|rcsb pdb:4MNG|rcsb pdb:4MQ7|rcsb pdb:4MX7|rcsb pdb:4NSK|rcsb pdb:4PG2|rcsb pdb:4PG9|rcsb pdb:4PGB|rcsb pdb:4PGC|rcsb pdb:4PGD|rcsb pdb:4PGE|rcsb pdb:4PV8|rcsb pdb:4PV9|rcsb pdb:4Y16|rcsb pdb:4Y2D|rcsb pdb:4Y4F|rcsb pdb:4Y4H|rcsb pdb:4Y4K|rcsb pdb:4ZAK|rcsb pdb:4ZUS|rcsb pdb:4ZUT|rcsb pdb:4ZUU|rcsb pdb:4ZUV|rcsb pdb:4ZUW|rcsb pdb:5OQG|rcsb pdb:5OQH|rcsb pdb:5OQI|rcsb pdb:5SWS|rcsb pdb:5SWZ|rcsb pdb:5E8N|rcsb pdb:5E8O|rcsb pdb:5E8P|rcsb pdb:5T7G|rcsb pdb:5EFI|rcsb pdb:5TIL|rcsb pdb:5TJE|rcsb pdb:5FKP|rcsb pdb:5TW2|rcsb pdb:5TW5|rcsb pdb:5IVX|rcsb pdb:5J6G|rcsb pdb:5VCJ|rcsb pdb:5J6H|rcsb pdb:5VCL|rcsb pdb:5JWD|rcsb pdb:5JWE|rcsb pdb:5KD4|rcsb pdb:5KD7|rcsb pdb:5WES|rcsb pdb:5M00|rcsb pdb:5M02|rcsb pdb:5WET|rcsb pdb:5WEU|rcsb pdb:5MZM|rcsb pdb:5OQF|rcsb pdb:5WLG|rcsb pdb:5WLI|rcsb pdb:6A97|rcsb pdb:6BMH|rcsb pdb:6BMK|rcsb pdb:6BNK|rcsb pdb:6BNL|rcsb pdb:6C5M|rcsb pdb:6C69|rcsb pdb:6C6A|rcsb pdb:6C6C|rcsb pdb:6C6E|rcsb pdb:6C6F|rcsb pdb:6C6H|rcsb pdb:6C6J|rcsb pdb:6CW6|rcsb pdb:6CW9|rcsb pdb:6CWB|rcsb pdb:6CWE|rcsb pdb:6CX5|rcsb pdb:6CX7|rcsb pdb:6CX9|rcsb pdb:6CXA|rcsb pdb:6CXE|rcsb pdb:6CXF|rcsb pdb:6CYW|rcsb pdb:6E1I|rcsb pdb:6G9Q|rcsb pdb:6G9R|rcsb pdb:6GB5|rcsb pdb:6GB6|rcsb pdb:6GB7|rcsb pdb:6H6D|rcsb pdb:6H6H|rcsb pdb:6I8C|rcsb pdb:6JQ2|rcsb pdb:6JQ3|rcsb pdb:6L9M|rcsb pdb:6L9N|rcsb pdb:6MIV|rcsb pdb:6MIY|rcsb pdb:6MJ4|rcsb pdb:6MJ6|rcsb pdb:6MJA|rcsb pdb:6MJI|rcsb pdb:6MJJ|rcsb pdb:6MJQ|rcsb pdb:6MP0|rcsb pdb:6MP1|rcsb pdb:6MSS|rcsb pdb:6OJP|rcsb pdb:6OMG|rcsb pdb:6OOR|rcsb pdb:7JI2|reactome:R-MMU-1236974|reactome:R-MMU-1236977|reactome:R-MMU-198933|reactome:R-MMU-2172127|reactome:R-MMU-2424491|reactome:R-MMU-6798695|reactome:R-MMU-983170|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|rcsb pdb:1BZ9|rcsb pdb:1CD1|rcsb pdb:1DDH|rcsb pdb:1FFN|rcsb pdb:1FFO|rcsb pdb:1FFP|rcsb pdb:1FG2|rcsb pdb:1FO0|rcsb pdb:1FZJ|rcsb pdb:1FZK|rcsb pdb:1FZM|rcsb pdb:1FZO|rcsb pdb:1G6R|rcsb pdb:1G7P|rcsb pdb:1G7Q|rcsb pdb:1HOC|rcsb pdb:1INQ|rcsb pdb:1JPF|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|rcsb pdb:1JPG|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|rcsb pdb:1JUF|mint:P01887|rcsb pdb:1BII|rcsb pdb:1K8D|rcsb pdb:1KBG|rcsb pdb:1KJ2|rcsb pdb:1BQH|rcsb pdb:1KJ3|rcsb pdb:1KPU|rcsb pdb:1KPV|rcsb pdb:1L6Q|rcsb pdb:1LD9|rcsb pdb:1LDP|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1LK2|rcsb pdb:1MHC|rcsb pdb:1MWA|rcsb pdb:1N3N|rcsb pdb:1N59|rcsb pdb:1N5A|rcsb pdb:1NAM|rcsb pdb:1NAN|rcsb pdb:1NEZ|rcsb pdb:1OSZ|rcsb pdb:1P1Z|rcsb pdb:1P4L|rcsb pdb:1PQZ|rcsb pdb:1QO3|rcsb pdb:1RJY|rcsb pdb:1RJZ|rcsb pdb:1RK0|rcsb pdb:1RK1|rcsb pdb:1S7Q|rcsb pdb:1S7R|rcsb pdb:1S7S|rcsb pdb:1S7T|rcsb pdb:1S7U|rcsb pdb:1S7V|rcsb pdb:1S7W|rcsb pdb:1S7X|rcsb pdb:1T0M|rcsb pdb:1T0N|rcsb pdb:1U58|rcsb pdb:1VAC|rcsb pdb:1VAD|rcsb pdb:1WBX|rcsb pdb:1WBY|rcsb pdb:1WBZ|rcsb pdb:1YN6|rcsb pdb:1YN7|rcsb pdb:1Z5L|rcsb pdb:1ZHB|rcsb pdb:1ZHN|rcsb pdb:1ZT1|rcsb pdb:1ZT7|rcsb pdb:2AKR|rcsb pdb:2CKB|rcsb pdb:2CLV|rcsb pdb:2CLZ|rcsb pdb:2FIK|rcsb pdb:2FO4|rcsb pdb:2FWO|rcsb pdb:2GAZ|rcsb pdb:2MHA|rcsb pdb:2OL3|rcsb pdb:2Q7Y|rcsb pdb:2QRI|rcsb pdb:2QRS|rcsb pdb:2QRT|rcsb pdb:2VAA|rcsb pdb:2VAB|rcsb pdb:2VE6|rcsb pdb:2ZOK|rcsb pdb:2ZOL|rcsb pdb:2ZSV|rcsb pdb:2ZSW|rcsb pdb:3ARB|rcsb pdb:3ARD|rcsb pdb:3ARE|rcsb pdb:3ARF|rcsb pdb:3ARG|rcsb pdb:3AU1|refseq:NP_033865.2|dip:DIP-6111N refseq:NP_031665.2|rcsb pdb:3GMQ|rcsb pdb:3GMR|rcsb pdb:3HE6|rcsb pdb:3HE7|rcsb pdb:3ILP|rcsb pdb:3ILQ|rcsb pdb:3MA7|rcsb pdb:3O8X|rcsb pdb:3O9W|rcsb pdb:3QI9|rcsb pdb:3QUX|rcsb pdb:3QUY|rcsb pdb:3QUZ|rcsb pdb:3RTQ|rcsb pdb:3RUG|rcsb pdb:3RZC|rcsb pdb:3SCM|rcsb pdb:3SDA|rcsb pdb:3SDC|rcsb pdb:3TVM|rcsb pdb:3UBX|rcsb pdb:4APQ|rcsb pdb:3SDD|rcsb pdb:3T1F|rcsb pdb:3TA3|rcsb pdb:3TN0|rcsb pdb:3TO4|rcsb pdb:4EI5|rcsb pdb:4IRS|rcsb pdb:4MNG|rcsb pdb:4MQ7|rcsb pdb:4MX7|rcsb pdb:4Y16|rcsb pdb:4Y2D|rcsb pdb:4Y4F|rcsb pdb:4Y4H|rcsb pdb:4Y4K|rcsb pdb:4ZAK|rcsb pdb:5EFI|rcsb pdb:5FKP|rcsb pdb:5TW2|rcsb pdb:5TW5|rcsb pdb:5VCJ|rcsb pdb:6BNK|rcsb pdb:6BNL|rcsb pdb:6C5M|rcsb pdb:6C69|rcsb pdb:6C6A|rcsb pdb:4IRJ|rcsb pdb:6CYW|rcsb pdb:6C6C|rcsb pdb:6C6E|rcsb pdb:6MIV|rcsb pdb:6MIY|rcsb pdb:6MJ4|rcsb pdb:6MJ6|rcsb pdb:6MJA|rcsb pdb:6MJI|rcsb pdb:6C6F|rcsb pdb:6MJJ|rcsb pdb:6MJQ|rcsb pdb:6C6H|rcsb pdb:6MSS|rcsb pdb:6OJP|rcsb pdb:6OMG|rcsb pdb:6OOR|rcsb pdb:6C6J|rcsb pdb:6CW6|rcsb pdb:6CW9|rcsb pdb:6CWB|rcsb pdb:6CWE|rcsb pdb:6CX5|rcsb pdb:6CX7|rcsb pdb:6CX9|rcsb pdb:6CXA|rcsb pdb:6CXE|rcsb pdb:6CXF|rcsb pdb:4ELM|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030882"(lipid antigen binding)|go:"GO:0030883"(endogenous lipid antigen binding)|go:"GO:0030884"(exogenous lipid antigen binding)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033084"(regulation of immature T cell proliferation in thymus)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045087"(innate immune response)|go:"GO:0048006"(antigen processing and presentation, endogenous lipid antigen via MHC class Ib)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0071723"(lipopeptide binding)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|rcsb pdb:3GMM|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|rcsb pdb:3GMN|rcsb pdb:1CD1|rcsb pdb:3GMO|rcsb pdb:1Z5L|rcsb pdb:1ZHN|rcsb pdb:2AKR|rcsb pdb:2FIK|rcsb pdb:2GAZ|rcsb pdb:2Q7Y|rcsb pdb:3ARB|rcsb pdb:3ARD|rcsb pdb:3ARE|rcsb pdb:3ARF|rcsb pdb:3ARG|rcsb pdb:3AU1|rcsb pdb:3G08|rcsb pdb:3GML|rcsb pdb:3GMP|dip:DIP-6127N|reactome:R-MMU-198933 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:grneeEsMKY5Sujo0fOBcfKu/qtA10090 rogid:QXLhy8YKCdX/IKdorMHBNpPNfbo10090 rigid:JDcxlztcQGlGg/av2sJa2SeqK4Q false sufficient binding region:21-119 sufficient binding region:22-336 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)