#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q12315 uniprotkb:P49686 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-12310|ensemblfungi:YDR192C|uniprotkb:D6VSH5 psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:nup42_yeast(display_long)|uniprotkb:NUP42(gene name)|psi-mi:NUP42(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:UIP1(gene name synonym)|uniprotkb:YDR192C(locus name)|uniprotkb:YD9346.04C(orf name)|uniprotkb:Nuclear pore protein NUP42(gene name synonym) psi-mi:"MI:0018"(two hybrid) Murphy et al. (1996) pubmed:8848052|doi:10.1038/383357a0|imex:IM-24892 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16211202|imex:IM-24892-1|dip:DIP-2737E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0071472"(cellular response to salt stress)|rcsb pdb:6B4E|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|ensemblfungi:YDR192C(gene)|ensemblfungi:YDR192C_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|refseq:NP_010478.3|sgd:S000002600|mint:P49686|dip:DIP-2313N psi-mi:"MI:0465"(dip) crc64:C9C6B1513AF95711 crc64:357F94914A5261F4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:uLrWo3FO8FYd7M+LoyJzqAtu+9w559292 rigid:zwyj14zRtQOze6jfTLwuRehBzCI false sufficient binding region:257-538|mutation decreasing interaction:356-356 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12315 uniprotkb:P49686 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-12310|ensemblfungi:YDR192C|uniprotkb:D6VSH5 psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:nup42_yeast(display_long)|uniprotkb:NUP42(gene name)|psi-mi:NUP42(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:UIP1(gene name synonym)|uniprotkb:YDR192C(locus name)|uniprotkb:YD9346.04C(orf name)|uniprotkb:Nuclear pore protein NUP42(gene name synonym) psi-mi:"MI:0018"(two hybrid) Murphy et al. (1996) pubmed:8848052|doi:10.1038/383357a0|imex:IM-24892 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16211245|imex:IM-24892-3|dip:DIP-2737E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0071472"(cellular response to salt stress)|rcsb pdb:6B4E|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|ensemblfungi:YDR192C(gene)|ensemblfungi:YDR192C_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|refseq:NP_010478.3|sgd:S000002600|mint:P49686|dip:DIP-2313N psi-mi:"MI:0465"(dip) crc64:C9C6B1513AF95711 crc64:357F94914A5261F4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:uLrWo3FO8FYd7M+LoyJzqAtu+9w559292 rigid:zwyj14zRtQOze6jfTLwuRehBzCI false sufficient binding region:257-538 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12315 uniprotkb:P49686 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W intact:EBI-12310|ensemblfungi:YDR192C|uniprotkb:D6VSH5 psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:nup42_yeast(display_long)|uniprotkb:NUP42(gene name)|psi-mi:NUP42(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:UIP1(gene name synonym)|uniprotkb:YDR192C(locus name)|uniprotkb:YD9346.04C(orf name)|uniprotkb:Nuclear pore protein NUP42(gene name synonym) psi-mi:"MI:0018"(two hybrid) Murphy et al. (1996) pubmed:8848052|doi:10.1038/383357a0|imex:IM-24892 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16211264|imex:IM-24892-4|dip:DIP-2737E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0071472"(cellular response to salt stress)|rcsb pdb:6B4E|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|ensemblfungi:YDR192C(gene)|ensemblfungi:YDR192C_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|refseq:NP_010478.3|sgd:S000002600|mint:P49686|dip:DIP-2313N psi-mi:"MI:0465"(dip) crc64:C9C6B1513AF95711 crc64:357F94914A5261F4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rogid:uLrWo3FO8FYd7M+LoyJzqAtu+9w559292 rigid:zwyj14zRtQOze6jfTLwuRehBzCI false necessary binding region:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02629 uniprotkb:Q12315 intact:EBI-11698|ensemblfungi:YKL068W|uniprotkb:D6VXL9 intact:EBI-7635|uniprotkb:D6VRE7|ensemblfungi:YDL207W psi-mi:nu100_yeast(display_long)|uniprotkb:NUP100(gene name)|psi-mi:NUP100(display_short)|uniprotkb:NSP100(gene name synonym)|uniprotkb:YKL068W(locus name)|uniprotkb:YKL336(orf name)|uniprotkb:Nuclear pore protein NUP100/NSP100(gene name synonym) psi-mi:gle1_yeast(display_long)|uniprotkb:BRR3(gene name synonym)|uniprotkb:RSS1(gene name synonym)|uniprotkb:YDL207W(locus name)|uniprotkb:D1049(orf name)|uniprotkb:GLE1(gene name)|psi-mi:GLE1(display_short)|uniprotkb:Nuclear pore protein GLE1(gene name synonym)|uniprotkb:RNA export factor GLE1(gene name synonym)|uniprotkb:Nucleoporin GLE1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Murphy et al. (1996) pubmed:8848052|doi:10.1038/383357a0|imex:IM-24892 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16211224|imex:IM-24892-2|dip:DIP-2736E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL068W(gene)|ensemblfungi:YKL068W_mRNA(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR025574|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|refseq:NP_012855.1|sgd:S000001551|mint:Q02629|dip:DIP-2351N sgd:S000002366|refseq:NP_010074.1|mint:Q12315|dip:DIP-2350N|ensemblfungi:YDL207W(gene)|ensemblfungi:YDL207W_mRNA(transcript)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|interpro:IPR012476(GLE1-like)|interpro:IPR038506|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:6B4E psi-mi:"MI:0465"(dip) crc64:D3985F9901BBAA51 crc64:C9C6B1513AF95711 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/08 2017/08/10 rogid:cdG/6Bz1Q30Of8KHqHp7FGTaOR8559292 rogid:1RI51/DOenI6DQvh2tErmJnDffI559292 rigid:MYIDc5wyTgkVR4FxhYDPRyxJYoE false sufficient binding region:2-595 sufficient binding region:257-538 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P69718 uniprotkb:P49686 intact:EBI-8540156|intact:MINT-8053053|uniprotkb:P04617 intact:EBI-12310|ensemblfungi:YDR192C|uniprotkb:D6VSH5 psi-mi:rev_hv1h3(display_long)|uniprotkb:rev(gene name)|psi-mi:rev(display_short)|uniprotkb:ART/TRS(gene name synonym)|uniprotkb:Anti-repression transactivator(gene name synonym)|uniprotkb:Regulator of expression of viral proteins(gene name synonym) psi-mi:nup42_yeast(display_long)|uniprotkb:NUP42(gene name)|psi-mi:NUP42(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:UIP1(gene name synonym)|uniprotkb:YDR192C(locus name)|uniprotkb:YD9346.04C(orf name)|uniprotkb:Nuclear pore protein NUP42(gene name synonym) psi-mi:"MI:0047"(far western blotting) Murphy et al. (1996) pubmed:8848052|doi:10.1038/383357a0|imex:IM-24892 taxid:11707(hv1h3)|taxid:11707("Human immunodeficiency virus type 1 group M subtype B (isolate HXB3)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-16211283|imex:IM-24892-5|dip:DIP-199889E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61764N|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0016032"(viral process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0051028"(mRNA transport)|interpro:IPR000625(Anti-repression trans-activator protein, REV protein)|rcsb pdb:3LPH|rcsb pdb:4PMI go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0071472"(cellular response to salt stress)|rcsb pdb:6B4E|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|ensemblfungi:YDR192C(gene)|ensemblfungi:YDR192C_mRNA(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|refseq:NP_010478.3|sgd:S000002600|mint:P49686|dip:DIP-2313N psi-mi:"MI:0465"(dip) comment:mint crc64:357F94914A5261F4 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/08 2017/08/10 rogid:MxSi+DZ5ahh2uJZAvCq/FnlK4UY11707 rogid:uLrWo3FO8FYd7M+LoyJzqAtu+9w559292 rigid:Cu3cSeHrh25+4eX0JuTfNIn2Np4 false mutation decreasing interaction:81-81|maltose binding protein tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)