#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0DN86 uniprotkb:P01215 intact:EBI-8626304|uniprotkb:P01233|uniprotkb:Q8WXL1|uniprotkb:B9ZVP5|uniprotkb:A1A5E0|uniprotkb:Q8WXL2|intact:MINT-1510897|uniprotkb:Q3SY41|uniprotkb:Q3KPI3|uniprotkb:Q8WXL4|uniprotkb:Q14000|uniprotkb:Q8WTT5|uniprotkb:Q13991|uniprotkb:Q8WXL3|ensembl:ENSP00000301408|ensembl:ENSP00000349954|ensembl:ENSP00000403649 intact:EBI-718913|ensembl:ENSP00000486024 psi-mi:cgb3_human(display_long)|uniprotkb:CGB5(gene name)|psi-mi:CGB5(display_short)|uniprotkb:CGB8(gene name)|psi-mi:CGB8(display_short)|uniprotkb:CGB3(gene name)|psi-mi:CGB3(display_short)|uniprotkb:CGB(gene name synonym)|uniprotkb:Choriogonadotropin subunit beta(gene name synonym)|uniprotkb:Chorionic gonadotropin chain beta(gene name synonym) psi-mi:glha_human(display_long)|uniprotkb:Anterior pituitary glycoprotein hormones common subunit alpha(gene name synonym)|uniprotkb:Follitropin alpha chain(gene name synonym)|uniprotkb:Follicle-stimulating hormone alpha chain(gene name synonym)|uniprotkb:Lutropin alpha chain(gene name synonym)|uniprotkb:Luteinizing hormone alpha chain(gene name synonym)|uniprotkb:Thyrotropin alpha chain(gene name synonym)|uniprotkb:Thyroid-stimulating hormone alpha chain(gene name synonym)|uniprotkb:Choriogonadotropin alpha chain(gene name synonym)|uniprotkb:Chorionic gonadotrophin subunit alpha(gene name synonym)|uniprotkb:CGA(gene name)|psi-mi:CGA(display_short) psi-mi:"MI:0114"(x-ray crystallography) Wu et al. (1994) pubmed:7922031|doi:"10.1016/s0969-2126(00)00054-x"|imex:IM-23576 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-16210354|imex:IM-23576-1|dip:DIP-11035E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149032.1|refseq:NP_000728.1|refseq:NP_149439.1|ensembl:ENSG00000104827(gene)|ensembl:ENSG00000189052(gene)|ensembl:ENSG00000213030(gene)|ensembl:ENST00000301408(transcript)|ensembl:ENST00000357383(transcript)|ensembl:ENST00000448456(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007292"(female gamete generation)|go:"GO:0009755"(hormone-mediated signaling pathway)|interpro:IPR001545(Gonadotropin, beta chain)|interpro:IPR006208(Cystine knot)|interpro:IPR018245|interpro:IPR029034|rcsb pdb:1HCN|rcsb pdb:1HRP|rcsb pdb:1QFW|rcsb pdb:1XUL|reactome:R-HSA-209822|reactome:R-HSA-8866910 refseq:NP_001239312.1|refseq:NP_000726.1|ensembl:ENSG00000135346(gene)|ensembl:ENST00000627148(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008406"(gonad development)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010893"(positive regulation of steroid biosynthetic process)|go:"GO:0016913"(follicle-stimulating hormone activity)|go:"GO:0016914"(follicle-stimulating hormone complex)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030878"(thyroid gland development)|go:"GO:0032275"(luteinizing hormone secretion)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046884"(follicle-stimulating hormone secretion)|go:"GO:0048589"(developmental growth)|interpro:IPR000476(Glycoprotein hormone alpha chain)|interpro:IPR029034|rcsb pdb:1DZ7|rcsb pdb:1E9J|rcsb pdb:1FL7|rcsb pdb:1HCN|rcsb pdb:1HD4|rcsb pdb:1HRP|rcsb pdb:1QFW|rcsb pdb:1XUL|rcsb pdb:1XWD|rcsb pdb:4AY9|rcsb pdb:4MQW|reactome:R-HSA-193048|reactome:R-HSA-193993|reactome:R-HSA-209822|reactome:R-HSA-209968|reactome:R-HSA-375281|reactome:R-HSA-418555|reactome:R-HSA-8866910|reactome:R-HSA-9660821|reactome:R-HSA-975578|dip:DIP-6182N psi-mi:"MI:0465"(dip) comment:mint|function:Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2017/08/08 2020/08/27 rogid:Fg4f/QYLQ+ZjWmJ1xx/ZNXwdvi89606 rogid:VQrwxotrJ6jIWVX7vhOF18yY6os9606 rigid:ANwLhEwjiSYmDmUCwmOMU735LbQ false sufficient binding region:25-165 sufficient binding region:25-116 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)