#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06492	uniprotkb:P04387	intact:EBI-7489933|uniprotkb:Q09I86|intact:MINT-275736|uniprotkb:B9VQH6	intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W	psi-mi:vp16_hhv11(display_long)|uniprotkb:Vmw65(gene name synonym)|uniprotkb:ICP25(gene name synonym)|uniprotkb:Alpha-TIF(gene name synonym)|uniprotkb:Alpha trans-inducing protein(gene name synonym)|uniprotkb:UL48(orf name)	psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name)	psi-mi:"MI:0096"(pull down)	Swaffield et al. (1995)	pubmed:7870180|doi:10.1038/374088a0|imex:IM-24886	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16210136|imex:IM-24886-1|dip:DIP-199875E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009137123.1|mint:P06492|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044161"(host cell cytoplasmic vesicle)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0046809"(replication compartment)|go:"GO:0051701"(biological process involved in interaction with host)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003174("Alpha trans-inducing protein (Alpha-TIF)")|interpro:IPR021051|interpro:IPR036538|rcsb pdb:16VP|rcsb pdb:2PHE|rcsb pdb:2PHG|dip:DIP-41776N	refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U	psi-mi:"MI:0465"(dip)	comment:mint|function:"Responsible for transcriptional activation of immediate early promoters (alpha genes). Activation requires the formation of a heteromeric complex with the host cell factor. These two proteins then assemble with the octamer motif-binding protein Oct-1 on the cis-acting target sequence: 5'-TAATGARAT-3'"	crc64:1492473684F3894C	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:8rAT+y7LSTotMP4XcD+eSyMpff010299	rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292	rigid:6mQWjxtKc3CORZcPHgIan7W9WeI	false	sufficient binding region:411-490|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13393	uniprotkb:Q01939	intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W	intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92	psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Swaffield et al. (1995)	pubmed:7870180|doi:10.1038/374088a0|imex:IM-24886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-16210178|imex:IM-24886-3|dip:DIP-10057E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393	go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N	psi-mi:"MI:0465"(dip)	crc64:50365FFF1D3718CE	crc64:9C59E92A0794F60F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/08	2017/08/10	rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292	rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292	rigid:RZqrkJvLV0PoIGKQVmxjSRMqj/Y	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P13393	uniprotkb:Q01939	intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W	intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92	psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Swaffield et al. (1995)	pubmed:7870180|doi:10.1038/374088a0|imex:IM-24886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16210195|imex:IM-24886-4|dip:DIP-10057E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393	go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N	psi-mi:"MI:0465"(dip)	crc64:50365FFF1D3718CE	crc64:9C59E92A0794F60F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292	rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292	rigid:RZqrkJvLV0PoIGKQVmxjSRMqj/Y	false	glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06492	uniprotkb:Q01939	intact:EBI-7489933|uniprotkb:Q09I86|intact:MINT-275736|uniprotkb:B9VQH6	intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92	psi-mi:vp16_hhv11(display_long)|uniprotkb:Vmw65(gene name synonym)|uniprotkb:ICP25(gene name synonym)|uniprotkb:Alpha-TIF(gene name synonym)|uniprotkb:Alpha trans-inducing protein(gene name synonym)|uniprotkb:UL48(orf name)	psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Swaffield et al. (1995)	pubmed:7870180|doi:10.1038/374088a0|imex:IM-24886	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16210214|imex:IM-24886-5|dip:DIP-75925E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_009137123.1|mint:P06492|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044161"(host cell cytoplasmic vesicle)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0046809"(replication compartment)|go:"GO:0051701"(biological process involved in interaction with host)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003174("Alpha trans-inducing protein (Alpha-TIF)")|interpro:IPR021051|interpro:IPR036538|rcsb pdb:16VP|rcsb pdb:2PHE|rcsb pdb:2PHG|dip:DIP-41776N	go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N	psi-mi:"MI:0465"(dip)	comment:mint|function:"Responsible for transcriptional activation of immediate early promoters (alpha genes). Activation requires the formation of a heteromeric complex with the host cell factor. These two proteins then assemble with the octamer motif-binding protein Oct-1 on the cis-acting target sequence: 5'-TAATGARAT-3'"	crc64:9C59E92A0794F60F	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:8rAT+y7LSTotMP4XcD+eSyMpff010299	rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292	rigid:gqFj0GK4Sa4DAYAxrJrSqTCizbY	false	sufficient binding region:411-490|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P04387	uniprotkb:P04386	intact:EBI-2061197|uniprotkb:D6VZC4|ensemblfungi:YML051W	intact:EBI-4407660|uniprotkb:D6W3C3|ensemblfungi:YPL248C	psi-mi:gal80_yeast(display_long)|uniprotkb:GAL80(gene name)|psi-mi:GAL80(display_short)|uniprotkb:YM9958.12(orf name)|uniprotkb:YM9827.01(orf name)|uniprotkb:YML051W(locus name)	psi-mi:gal4_yeast(display_long)|uniprotkb:GAL4(gene name)|psi-mi:GAL4(display_short)|uniprotkb:YPL248C(locus name)	psi-mi:"MI:0096"(pull down)	Swaffield et al. (1995)	pubmed:7870180|doi:10.1038/374088a0|imex:IM-24886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16210157|imex:IM-24886-2|dip:DIP-1195E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013661.1|sgd:S000004515|dip:DIP-594N|mint:P04387|ensemblfungi:YML051W(gene)|ensemblfungi:YML051W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR036291|rcsb pdb:3BTS|rcsb pdb:3BTU|rcsb pdb:3BTV|rcsb pdb:3V2U	refseq:NP_015076.1|sgd:S000006169|mint:P04386|dip:DIP-593N|ensemblfungi:YPL248C(gene)|ensemblfungi:YPL248C_mRNA(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR005600(Gal4-like dimerisation domain)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864|rcsb pdb:1AW6|rcsb pdb:1D66|rcsb pdb:1HBW|rcsb pdb:3BTS|rcsb pdb:3COQ	psi-mi:"MI:0465"(dip)	crc64:1492473684F3894C	crc64:29D7FF68B0B05880	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:6ryfff/vlV8NQ3Fk1U8RWaUWkxE559292	rogid:3bV9oJGeVBncvgN7655e/XjQzOo559292	rigid:o+uSJc/l2BmpuP3Ik6E353rv+F8	false	-	sufficient binding region:841-875|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01939	uniprotkb:P04386	intact:EBI-13914|ensemblfungi:YGL048C|uniprotkb:D6VU92	intact:EBI-4407660|uniprotkb:D6W3C3|ensemblfungi:YPL248C	psi-mi:prs8_yeast(display_long)|uniprotkb:TBPY(gene name synonym)|uniprotkb:TBY1(gene name synonym)|uniprotkb:YGL048C(locus name)|uniprotkb:RPT6(gene name)|psi-mi:RPT6(display_short)|uniprotkb:CIM3(gene name synonym)|uniprotkb:CRL3(gene name synonym)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Protein SUG1(gene name synonym)|uniprotkb:Protein CIM3(gene name synonym)|uniprotkb:Tat-binding protein TBY1(gene name synonym)	psi-mi:gal4_yeast(display_long)|uniprotkb:GAL4(gene name)|psi-mi:GAL4(display_short)|uniprotkb:YPL248C(locus name)	psi-mi:"MI:0096"(pull down)	Swaffield et al. (1995)	pubmed:7870180|doi:10.1038/374088a0|imex:IM-24886	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-16210235|imex:IM-24886-6|dip:DIP-1197E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070682"(proteasome regulatory particle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035261|interpro:IPR041569|rcsb pdb:3JCO|rcsb pdb:3JCP|rcsb pdb:4CR2|rcsb pdb:4CR3|rcsb pdb:4CR4|rcsb pdb:5A5B|rcsb pdb:5MP9|rcsb pdb:5MPA|rcsb pdb:5MPB|rcsb pdb:5MPC|rcsb pdb:5WVI|rcsb pdb:6EF3|rcsb pdb:6FVT|rcsb pdb:6FVU|rcsb pdb:6FVV|rcsb pdb:6FVW|rcsb pdb:6FVX|rcsb pdb:6FVY|rcsb pdb:6J2C|rcsb pdb:6J2N|rcsb pdb:6J2Q|rcsb pdb:6J2X|rcsb pdb:6J30|reactome:R-SCE-1236978|reactome:R-SCE-174113|reactome:R-SCE-5668541|rcsb pdb:5WVK|rcsb pdb:6EF0|rcsb pdb:6EF1|rcsb pdb:6EF2|reactome:R-SCE-5687128|reactome:R-SCE-5689880|reactome:R-SCE-68949|reactome:R-SCE-69017|reactome:R-SCE-69601|reactome:R-SCE-75815|reactome:R-SCE-8948751|reactome:R-SCE-983168|reactome:R-SCE-8854050|ensemblfungi:YGL048C(gene)|ensemblfungi:YGL048C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|refseq:NP_011467.1|sgd:S000003016|mint:Q01939|dip:DIP-979N	refseq:NP_015076.1|sgd:S000006169|mint:P04386|dip:DIP-593N|ensemblfungi:YPL248C(gene)|ensemblfungi:YPL248C_mRNA(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR005600(Gal4-like dimerisation domain)|interpro:IPR007219(Fungal specific transcription factor)|interpro:IPR036864|rcsb pdb:1AW6|rcsb pdb:1D66|rcsb pdb:1HBW|rcsb pdb:3BTS|rcsb pdb:3COQ	psi-mi:"MI:0465"(dip)	crc64:9C59E92A0794F60F	crc64:29D7FF68B0B05880	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/08	2017/08/10	rogid:lvkwNLqTeoit17Ax4mP0+WiGzsY559292	rogid:3bV9oJGeVBncvgN7655e/XjQzOo559292	rigid:WC0wYXQKcJXr1ort/Rv3gYWz95k	false	-	sufficient binding region:841-875|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)