#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96Q07 uniprotkb:Q9C098 intact:EBI-2510245|ensembl:ENSP00000418751|ensembl:ENSP00000497066|uniprotkb:Q494V9|uniprotkb:Q96M00|uniprotkb:Q494W1 intact:EBI-1383502|ensembl:ENSP00000394484 psi-mi:btbd9_human(display_long)|uniprotkb:BTBD9(gene name)|psi-mi:BTBD9(display_short)|uniprotkb:KIAA1880(gene name synonym) psi-mi:dclk3_human(display_long)|uniprotkb:DCLK3(gene name)|psi-mi:DCLK3(display_short)|uniprotkb:DCAMKL3(gene name synonym)|uniprotkb:DCDC3C(gene name synonym)|uniprotkb:KIAA1765(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 3(gene name synonym)|uniprotkb:Doublecortin-like kinase 3(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Galvan et al. (2018) pubmed:29534157|imex:IM-26152 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16518576|imex:IM-26152-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183826(gene)|ensembl:ENST00000481247(transcript)|ensembl:ENST00000649492(transcript)|go:"GO:0007616"(long-term memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042748"(circadian sleep/wake cycle, non-REM sleep)|go:"GO:0048512"(circadian behavior)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050951"(sensory perception of temperature stimulus)|go:"GO:0060586"(multicellular organismal iron ion homeostasis)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR034091|refseq:XP_011512581.1|refseq:NP_001092742.1|refseq:NP_001165889.1|refseq:NP_443125.1|refseq:NP_689946.2 refseq:NP_208382.1|refseq:XP_011532469.1|ensembl:ENSG00000163673(gene)|ensembl:ENST00000416516(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) - - - figure legend:Figure 5B, Table S1 -1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/25 2017/10/25 rogid:cjdtAwudivBKATkCJ5R/vYLhx4g9606 rogid:3pz7T/EIrA3CdVzvt+3+BGecr+o9606 rigid:bSt+8a7pHXTYcpk406LLM7vIU9Q false - sufficient binding region:162-632 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NSC2 uniprotkb:Q9C098 intact:EBI-11317266|uniprotkb:Q9P1R0|uniprotkb:Q99881|uniprotkb:Q9NSC3|ensembl:ENSP00000251020 intact:EBI-1383502|ensembl:ENSP00000394484 psi-mi:sall1_human(display_long)|uniprotkb:SAL1(gene name synonym)|uniprotkb:Spalt-like transcription factor 1(gene name synonym)|uniprotkb:ZNF794(gene name synonym)|uniprotkb:Zinc finger protein 794(gene name synonym)|uniprotkb:Zinc finger protein SALL1(gene name synonym)|uniprotkb:Zinc finger protein Spalt-1(gene name synonym)|uniprotkb:SALL1(gene name)|psi-mi:SALL1(display_short) psi-mi:dclk3_human(display_long)|uniprotkb:DCLK3(gene name)|psi-mi:DCLK3(display_short)|uniprotkb:DCAMKL3(gene name synonym)|uniprotkb:DCDC3C(gene name synonym)|uniprotkb:KIAA1765(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 3(gene name synonym)|uniprotkb:Doublecortin-like kinase 3(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Galvan et al. (2018) pubmed:29534157|imex:IM-26152 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16518582|imex:IM-26152-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000251020|ensembl:ENST00000440970|ensembl:ENSP00000407914|refseq:NP_001121364.1|refseq:NP_002959.2|refseq:XP_006721304.1|refseq:XP_011521556.1|ensembl:ENSG00000103449(gene)|ensembl:ENST00000251020(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003337"(mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008406"(gonad development)|go:"GO:0010369"(chromocenter)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021889"(olfactory bulb interneuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031129"(inductive cell-cell signaling)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0060173"(limb development)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0072092"(ureteric bud invasion)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|reactome:R-HSA-2892247 refseq:NP_208382.1|refseq:XP_011532469.1|ensembl:ENSG00000163673(gene)|ensembl:ENST00000416516(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) - - - figure legend:Figure 5B, Table S1 -2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/25 2017/10/25 rogid:DBQLgD+Ff+UK80hJsSpeecFzbJQ9606 rogid:3pz7T/EIrA3CdVzvt+3+BGecr+o9606 rigid:7uDs+YVTq0aVhY2brH4dKNP+w/M false - sufficient binding region:162-632 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HCM9 uniprotkb:Q9C098 intact:EBI-739510|uniprotkb:Q5STG4|uniprotkb:Q76BL3|uniprotkb:Q8IYT9|uniprotkb:Q96IB6|ensembl:ENSP00000365844|ensembl:ENSP00000373096|ensembl:ENSP00000379796|ensembl:ENSP00000391917|ensembl:ENSP00000397043|ensembl:ENSP00000398355|ensembl:ENSP00000409902|ensembl:ENSP00000411949|ensembl:ENSP00000447835|ensembl:ENSP00000448462|ensembl:ENSP00000448572|ensembl:ENSP00000449272|ensembl:ENSP00000449847|ensembl:ENSP00000450288|uniprotkb:Q5STG3 intact:EBI-1383502|ensembl:ENSP00000394484 psi-mi:tri39_human(display_long)|uniprotkb:TRIM39(gene name)|psi-mi:TRIM39(display_short)|uniprotkb:RNF23(gene name synonym)|uniprotkb:TFP(gene name synonym)|uniprotkb:RING finger protein 23(gene name synonym)|uniprotkb:Testis-abundant finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 39(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM39(gene name synonym) psi-mi:dclk3_human(display_long)|uniprotkb:DCLK3(gene name)|psi-mi:DCLK3(display_short)|uniprotkb:DCAMKL3(gene name synonym)|uniprotkb:DCDC3C(gene name synonym)|uniprotkb:KIAA1765(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 3(gene name synonym)|uniprotkb:Doublecortin-like kinase 3(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Galvan et al. (2018) pubmed:29534157|imex:IM-26152 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16518588|imex:IM-26152-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000204599(gene)|ensembl:ENSG00000206495(gene)|ensembl:ENSG00000224994(gene)|ensembl:ENSG00000226437(gene)|ensembl:ENSG00000229929(gene)|ensembl:ENSG00000230308(gene)|ensembl:ENSG00000232839(gene)|ensembl:ENST00000376656(transcript)|ensembl:ENST00000383602(transcript)|ensembl:ENST00000396547(transcript)|ensembl:ENST00000413715(transcript)|ensembl:ENST00000424575(transcript)|ensembl:ENST00000445206(transcript)|ensembl:ENST00000426469(transcript)|ensembl:ENST00000451715(transcript)|ensembl:ENST00000547030(transcript)|ensembl:ENST00000548002(transcript)|ensembl:ENST00000549841(transcript)|ensembl:ENST00000550282(transcript)|ensembl:ENST00000552337(transcript)|ensembl:ENST00000552520(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035033|interpro:IPR043136|mint:Q9HCM9|rcsb pdb:2DID|rcsb pdb:2DIF|rcsb pdb:2ECJ|reactome:R-HSA-983168|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:NP_067076.2|refseq:NP_742013.1 refseq:NP_208382.1|refseq:XP_011532469.1|ensembl:ENSG00000163673(gene)|ensembl:ENST00000416516(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) - - - figure legend:Figure 5B, Table S1 -3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/25 2017/10/25 rogid:xMCXGcMTqCjzLQzC53o81S4gqZA9606 rogid:3pz7T/EIrA3CdVzvt+3+BGecr+o9606 rigid:Jjhpho/1YXSUIw2d8Nf1tOYsUao false - sufficient binding region:162-632 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75528 uniprotkb:Q9C098 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 intact:EBI-1383502|ensembl:ENSP00000394484 psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:dclk3_human(display_long)|uniprotkb:DCLK3(gene name)|psi-mi:DCLK3(display_short)|uniprotkb:DCAMKL3(gene name synonym)|uniprotkb:DCDC3C(gene name synonym)|uniprotkb:KIAA1765(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 3(gene name synonym)|uniprotkb:Doublecortin-like kinase 3(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Galvan et al. (2018) pubmed:29534157|imex:IM-26152 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16518594|imex:IM-26152-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 refseq:NP_208382.1|refseq:XP_011532469.1|ensembl:ENSG00000163673(gene)|ensembl:ENST00000416516(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) - - - figure legend:Figure 5B, Table S1 -4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/25 2017/10/25 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rogid:3pz7T/EIrA3CdVzvt+3+BGecr+o9606 rigid:Tv02KhC/iu158icuUK2iChLpnGg false - sufficient binding region:162-632 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17014 uniprotkb:Q9C098 intact:EBI-11278550|uniprotkb:A8MYC4|uniprotkb:A8WFQ8|uniprotkb:B2RNQ7|uniprotkb:B4DF45|uniprotkb:Q6N016|uniprotkb:Q8NHZ0|uniprotkb:Q9H9P0|uniprotkb:Q9ULZ6|ensembl:ENSP00000385939 intact:EBI-1383502|ensembl:ENSP00000394484 psi-mi:znf12_human(display_long)|uniprotkb:ZNF12(gene name)|psi-mi:ZNF12(display_short)|uniprotkb:GIOT3(gene name synonym)|uniprotkb:Gonadotropin-inducible ovary transcription repressor 3(gene name synonym)|uniprotkb:KOX3(gene name synonym)|uniprotkb:ZNF325(gene name synonym)|uniprotkb:Zinc finger protein 325(gene name synonym)|uniprotkb:Zinc finger protein KOX3(gene name synonym) psi-mi:dclk3_human(display_long)|uniprotkb:DCLK3(gene name)|psi-mi:DCLK3(display_short)|uniprotkb:DCAMKL3(gene name synonym)|uniprotkb:DCDC3C(gene name synonym)|uniprotkb:KIAA1765(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 3(gene name synonym)|uniprotkb:Doublecortin-like kinase 3(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Galvan et al. (2018) pubmed:29534157|imex:IM-26152 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16518600|imex:IM-26152-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008887.2|refseq:NP_057349.2|ensembl:ENSG00000164631(gene)|ensembl:ENST00000405858(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|reactome:R-HSA-212436|interpro:IPR036236 refseq:NP_208382.1|refseq:XP_011532469.1|ensembl:ENSG00000163673(gene)|ensembl:ENST00000416516(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) - - - figure legend:Figure 5B, Table S1 -5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/25 2017/10/25 rogid:v2lN/zGrfrtkzgiKNmc4684fnuU9606 rogid:3pz7T/EIrA3CdVzvt+3+BGecr+o9606 rigid:6D0CDZcszdhh0BQODnu4IiewQ6I false - sufficient binding region:162-632 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60281 uniprotkb:Q9C098 intact:EBI-1224010|uniprotkb:Q9H8G3|uniprotkb:Q9H8J4|uniprotkb:Q5W0B2|uniprotkb:Q7Z3L7|intact:EBI-28971048|ensembl:ENSP00000358590 intact:EBI-1383502|ensembl:ENSP00000394484 psi-mi:zn292_human(display_long)|uniprotkb:ZNF292(gene name)|psi-mi:ZNF292(display_short)|uniprotkb:KIAA0530(gene name synonym) psi-mi:dclk3_human(display_long)|uniprotkb:DCLK3(gene name)|psi-mi:DCLK3(display_short)|uniprotkb:DCAMKL3(gene name synonym)|uniprotkb:DCDC3C(gene name synonym)|uniprotkb:KIAA1765(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 3(gene name synonym)|uniprotkb:Doublecortin-like kinase 3(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Galvan et al. (2018) pubmed:29534157|imex:IM-26152 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16518612|imex:IM-26152-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000358590|refseq:NP_055836.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensembl:ENSG00000188994(gene)|interpro:IPR036236|mint:O60281|rcsb pdb:1X3C|ensembl:ENST00000369577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus) refseq:NP_208382.1|refseq:XP_011532469.1|ensembl:ENSG00000163673(gene)|ensembl:ENST00000416516(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) - - - figure legend:Figure 5B, Table S1 -6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/25 2017/10/25 rogid:4Ss6SyxGv1bSjSBhSjquUKutB349606 rogid:3pz7T/EIrA3CdVzvt+3+BGecr+o9606 rigid:eGcGWo7z3ga46t9AEJLAAtn9Enk false - sufficient binding region:162-632 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8N895 uniprotkb:Q9C098 intact:EBI-2813661|uniprotkb:Q7RTV4|ensembl:ENSP00000313158|uniprotkb:Q5HYI9 intact:EBI-1383502|ensembl:ENSP00000394484 psi-mi:zn366_human(display_long)|uniprotkb:ZNF366(gene name)|psi-mi:ZNF366(display_short)|uniprotkb:Dendritic cell-specific transcript protein(gene name synonym) psi-mi:dclk3_human(display_long)|uniprotkb:DCLK3(gene name)|psi-mi:DCLK3(display_short)|uniprotkb:DCAMKL3(gene name synonym)|uniprotkb:DCDC3C(gene name synonym)|uniprotkb:KIAA1765(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 3(gene name synonym)|uniprotkb:Doublecortin-like kinase 3(gene name synonym)|uniprotkb:Doublecortin domain-containing protein 3C(gene name synonym) psi-mi:"MI:0018"(two hybrid) Galvan et al. (2018) pubmed:29534157|imex:IM-26152 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16518618|imex:IM-26152-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689838.1|ensembl:ENSG00000178175(gene)|ensembl:ENST00000318442(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043627"(response to estrogen)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_208382.1|refseq:XP_011532469.1|ensembl:ENSG00000163673(gene)|ensembl:ENST00000416516(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) - - - figure legend:Figure 5B, Table S1 -7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/10/25 2017/10/25 rogid:eE4EW7+MMZfDglVayxF2rOZpFDE9606 rogid:3pz7T/EIrA3CdVzvt+3+BGecr+o9606 rigid:MK9YZwHM3J1Ps9INA0w7jmvTFTU false - sufficient binding region:162-632 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BWQ5 uniprotkb:O75528 intact:EBI-16518538|ensembl:ENSMUSP00000107510|uniprotkb:Q1A748 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:dclk3_mouse(display_long)|uniprotkb:Dclk3(gene name)|psi-mi:Dclk3(display_short)|uniprotkb:Dcamkl3(gene name synonym)|uniprotkb:CLICK-I and II-related(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 3(gene name synonym)|uniprotkb:Doublecortin-like kinase 3(gene name synonym) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Galvan et al. (2018) pubmed:29534157|imex:IM-26152 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16518624|imex:IM-26152-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032500(gene)|ensembl:ENSMUST00000111879(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036572|refseq:NP_766516.2 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:Figure 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/10/25 2017/10/26 rogid:T+MnOorEItUh9AwpX66IURDRWQw10090 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:5PUxhtC2UEg5WSpMIKYYwxoKrVQ false ha tag:c-c|sufficient binding region:330-790 v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8BWQ5 uniprotkb:O75528 intact:EBI-16518538|ensembl:ENSMUSP00000107510|uniprotkb:Q1A748 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:dclk3_mouse(display_long)|uniprotkb:Dclk3(gene name)|psi-mi:Dclk3(display_short)|uniprotkb:Dcamkl3(gene name synonym)|uniprotkb:CLICK-I and II-related(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 3(gene name synonym)|uniprotkb:Doublecortin-like kinase 3(gene name synonym) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Galvan et al. (2018) pubmed:29534157|imex:IM-26152 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16518634|imex:IM-26152-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032500(gene)|ensembl:ENSMUST00000111879(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036572|refseq:NP_766516.2 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:Figure 5Ci|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/10/25 2017/10/26 rogid:T+MnOorEItUh9AwpX66IURDRWQw10090 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:5PUxhtC2UEg5WSpMIKYYwxoKrVQ false ha tag:c-c|sufficient binding region:330-790 v5 tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)