#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NY61 uniprotkb:O75528 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0018"(two hybrid) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16717476|imex:IM-26307-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - - figure legend:Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/12/19 2018/01/04 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:aaAMCfCjBUa+ADm0MVMTcEjaOG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NY61 uniprotkb:O75478 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:"MI:0018"(two hybrid) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16717480|imex:IM-26307-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N - - - figure legend:Figure 1B-2, 2A|comment:For both ADA2 isoforms, the region between the SANT domain and the Ada1 box also may be critical for interaction with AATF.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/12/19 2018/01/04 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 rigid:RcKeJR4GM+i2GunvMtdj5GRwNYE false - necessary binding region:87-167|sufficient binding region:1-347 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NY61 uniprotkb:Q86TJ2 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 intact:EBI-2512219|uniprotkb:Q6MZG9|uniprotkb:B3KSN0|uniprotkb:B3KU86|uniprotkb:A4QMR7|uniprotkb:A0AUJ8|ensembl:ENSP00000308022 psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:tad2b_human(display_long)|uniprotkb:TADA2B(gene name)|psi-mi:TADA2B(display_short)|uniprotkb:ADA2B(gene name synonym)|uniprotkb:ADA2-like protein beta(gene name synonym) psi-mi:"MI:0018"(two hybrid) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16717484|imex:IM-26307-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 refseq:XP_011511897.1|refseq:NP_689506.2|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:Q86TJ2|reactome:R-HSA-3214847|reactome:R-HSA-5689880|interpro:IPR009057(Homeodomain-like)|ensembl:ENSG00000173011(gene)|ensembl:ENST00000310074(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030914"|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding) - - - figure legend:Figure 1B-3, 2B|comment:For both ADA2 isoforms, the region between the SANT domain and the Ada1 box also may be critical for interaction with AATF.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/12/19 2018/01/04 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rogid:ShA8/bknqf6XcaEWL3YFWOz9s9c9606 rigid:zveMgtx098br73m331603zq1uAE false - sufficient binding region:1-120|necessary binding region:92-120 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NY61 uniprotkb:Q92830 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 intact:EBI-477622|uniprotkb:Q9UCW1|uniprotkb:Q8N1A2|ensembl:ENSP00000225916 psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:kat2a_human(display_long)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16717488|imex:IM-26307-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 refseq:NP_066564.2|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q92830|rcsb pdb:1F68|rcsb pdb:1Z4R|rcsb pdb:3D7C|rcsb pdb:5H84|rcsb pdb:5H86|rcsb pdb:5MLJ|rcsb pdb:5TRL|rcsb pdb:5TRM|rcsb pdb:6J3P|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5689880|reactome:R-HSA-73762|reactome:R-HSA-8941856|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|reactome:R-HSA-9013508|reactome:R-HSA-9013695|refseq:XP_016879937.1|dip:DIP-28146N - - - figure legend:Figure 1B-4, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/12/19 2018/01/04 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606 rigid:OcpKYFpCnQHt+7y7oQuGI3DpcVA false - sufficient binding region:428-837|necessary binding region:428-532 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O75528 uniprotkb:Q9NY61 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16717627|imex:IM-26307-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 - - - figure legend:Figure 3-1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/12/19 2018/01/04 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:aaAMCfCjBUa+ADm0MVMTcEjaOG8 false cyan fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O75478 uniprotkb:Q9NY61 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16717670|imex:IM-26307-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 - - - figure legend:Figure 3-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/12/19 2018/01/04 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:RcKeJR4GM+i2GunvMtdj5GRwNYE false cyan fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86TJ2 uniprotkb:Q9NY61 intact:EBI-2512219|uniprotkb:Q6MZG9|uniprotkb:B3KSN0|uniprotkb:B3KU86|uniprotkb:A4QMR7|uniprotkb:A0AUJ8|ensembl:ENSP00000308022 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:tad2b_human(display_long)|uniprotkb:TADA2B(gene name)|psi-mi:TADA2B(display_short)|uniprotkb:ADA2B(gene name synonym)|uniprotkb:ADA2-like protein beta(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16717678|imex:IM-26307-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011511897.1|refseq:NP_689506.2|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:Q86TJ2|reactome:R-HSA-3214847|reactome:R-HSA-5689880|interpro:IPR009057(Homeodomain-like)|ensembl:ENSG00000173011(gene)|ensembl:ENST00000310074(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030914"|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 - - - figure legend:Figure 3-3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/12/19 2018/01/04 rogid:ShA8/bknqf6XcaEWL3YFWOz9s9c9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:zveMgtx098br73m331603zq1uAE false cyan fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q92830 uniprotkb:Q9NY61 intact:EBI-477622|uniprotkb:Q9UCW1|uniprotkb:Q8N1A2|ensembl:ENSP00000225916 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:kat2a_human(display_long)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16717686|imex:IM-26307-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066564.2|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q92830|rcsb pdb:1F68|rcsb pdb:1Z4R|rcsb pdb:3D7C|rcsb pdb:5H84|rcsb pdb:5H86|rcsb pdb:5MLJ|rcsb pdb:5TRL|rcsb pdb:5TRM|rcsb pdb:6J3P|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5689880|reactome:R-HSA-73762|reactome:R-HSA-8941856|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|reactome:R-HSA-9013508|reactome:R-HSA-9013695|refseq:XP_016879937.1|dip:DIP-28146N refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 - - - figure legend:Figure 3-4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/12/19 2018/01/04 rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:OcpKYFpCnQHt+7y7oQuGI3DpcVA false cyan fluorescent protein tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q86TJ2 uniprotkb:Q9NY61 intact:EBI-2512219|uniprotkb:Q6MZG9|uniprotkb:B3KSN0|uniprotkb:B3KU86|uniprotkb:A4QMR7|uniprotkb:A0AUJ8|ensembl:ENSP00000308022 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:tad2b_human(display_long)|uniprotkb:TADA2B(gene name)|psi-mi:TADA2B(display_short)|uniprotkb:ADA2B(gene name synonym)|uniprotkb:ADA2-like protein beta(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0663"(confocal microscopy) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16717724|imex:IM-26307-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011511897.1|refseq:NP_689506.2|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:Q86TJ2|reactome:R-HSA-3214847|reactome:R-HSA-5689880|interpro:IPR009057(Homeodomain-like)|ensembl:ENSG00000173011(gene)|ensembl:ENST00000310074(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030914"|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus) - - figure legend:Figure 4-B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/12/19 2018/01/04 rogid:ShA8/bknqf6XcaEWL3YFWOz9s9c9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:zveMgtx098br73m331603zq1uAE false cyan fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q92830 uniprotkb:Q9NY61 intact:EBI-477622|uniprotkb:Q9UCW1|uniprotkb:Q8N1A2|ensembl:ENSP00000225916 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:kat2a_human(display_long)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0663"(confocal microscopy) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16717744|imex:IM-26307-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066564.2|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q92830|rcsb pdb:1F68|rcsb pdb:1Z4R|rcsb pdb:3D7C|rcsb pdb:5H84|rcsb pdb:5H86|rcsb pdb:5MLJ|rcsb pdb:5TRL|rcsb pdb:5TRM|rcsb pdb:6J3P|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5689880|reactome:R-HSA-73762|reactome:R-HSA-8941856|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|reactome:R-HSA-9013508|reactome:R-HSA-9013695|refseq:XP_016879937.1|dip:DIP-28146N refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 go:"GO:0005654"(nucleoplasm) - - figure legend:Figure 4-C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/12/19 2018/01/04 rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:OcpKYFpCnQHt+7y7oQuGI3DpcVA false cyan fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:O75478 uniprotkb:Q9NY61 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0663"(confocal microscopy) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16717786|imex:IM-26307-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - figure legend:Figure 4-A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2017/12/19 2018/01/04 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:RcKeJR4GM+i2GunvMtdj5GRwNYE false cyan fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:O75478 uniprotkb:Q9NY61 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0663"(confocal microscopy) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16717705|imex:IM-26307-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - figure legend:Supplementary Figure 1-A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/12/19 2018/01/04 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:RcKeJR4GM+i2GunvMtdj5GRwNYE false cyan fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q92830 uniprotkb:Q9NY61 intact:EBI-477622|uniprotkb:Q9UCW1|uniprotkb:Q8N1A2|ensembl:ENSP00000225916 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:kat2a_human(display_long)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0663"(confocal microscopy) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16717777|imex:IM-26307-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066564.2|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q92830|rcsb pdb:1F68|rcsb pdb:1Z4R|rcsb pdb:3D7C|rcsb pdb:5H84|rcsb pdb:5H86|rcsb pdb:5MLJ|rcsb pdb:5TRL|rcsb pdb:5TRM|rcsb pdb:6J3P|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5689880|reactome:R-HSA-73762|reactome:R-HSA-8941856|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|reactome:R-HSA-9013508|reactome:R-HSA-9013695|refseq:XP_016879937.1|dip:DIP-28146N refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 go:"GO:0005654"(nucleoplasm) - - figure legend:Supplementary Figure 1 -C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/12/19 2018/01/04 rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:OcpKYFpCnQHt+7y7oQuGI3DpcVA false cyan fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q86TJ2 uniprotkb:Q9NY61 intact:EBI-2512219|uniprotkb:Q6MZG9|uniprotkb:B3KSN0|uniprotkb:B3KU86|uniprotkb:A4QMR7|uniprotkb:A0AUJ8|ensembl:ENSP00000308022 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:tad2b_human(display_long)|uniprotkb:TADA2B(gene name)|psi-mi:TADA2B(display_short)|uniprotkb:ADA2B(gene name synonym)|uniprotkb:ADA2-like protein beta(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0663"(confocal microscopy) Caliskan et al. (2016) pubmed:29232376|imex:IM-26307 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16717767|imex:IM-26307-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011511897.1|refseq:NP_689506.2|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:Q86TJ2|reactome:R-HSA-3214847|reactome:R-HSA-5689880|interpro:IPR009057(Homeodomain-like)|ensembl:ENSG00000173011(gene)|ensembl:ENST00000310074(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030914"|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894 go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus) - - figure legend:Supplementary Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/12/19 2018/01/04 rogid:ShA8/bknqf6XcaEWL3YFWOz9s9c9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rigid:zveMgtx098br73m331603zq1uAE false cyan fluorescent protein tag:?-? yellow fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)