#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96RS6 uniprotkb:Q9UL18 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-527363|uniprotkb:Q5TA57|uniprotkb:Q6P4S0|ensembl:ENSP00000362300|ensembl:ENSP00000501450 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:ago1_human(display_long)|uniprotkb:AGO1(gene name)|psi-mi:AGO1(display_short)|uniprotkb:Argonaute RISC catalytic component 1(gene name synonym)|uniprotkb:EIF2C1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 1(gene name synonym)|uniprotkb:Putative RNA-binding protein Q99(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 dip:DIP-29193N|refseq:NP_036331.1|ensembl:ENSG00000092847(gene)|ensembl:ENST00000373204(transcript)|ensembl:ENST00000674304(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016442"(RISC complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UL18|rcsb pdb:1SI2|rcsb pdb:1SI3|rcsb pdb:4KRE|rcsb pdb:4KRF|rcsb pdb:4KXT|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|refseq:NP_001304051.1|refseq:NP_001304052.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:l/WmIsnfJjifEOoxOyG9zDo2ljQ9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9C0C2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2104458|uniprotkb:Q6PJ35|uniprotkb:Q6ZV74|uniprotkb:A7E2F8|intact:EBI-28975617|ensembl:ENSP00000350990|ensembl:ENSP00000437271 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:tb182_human(display_long)|uniprotkb:TNKS1BP1(gene name)|psi-mi:TNKS1BP1(display_short)|uniprotkb:KIAA1741(gene name synonym)|uniprotkb:TAB182(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:XP_006718788.1|ensembl:ENSP00000350990|ensembl:ENSP00000437271|refseq:NP_203754.2|ensembl:ENSG00000149115(gene)|ensembl:ENST00000358252(transcript)|ensembl:ENST00000532437(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR032764|interpro:IPR040006|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:pOIaK7wn7iYvUHbSA0kUZlIgtgw9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 intact:EBI-8011851 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:MINT-8395041 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:f5gyc1_human(display_short)|psi-mi:EBI-8011851(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:F5GYC1(uniprot-removed-ac) - - comment:mint|comment:homomint|no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:TMMmEXqhZmllyr2F+jqBoFxe56A9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P35556 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-6164392|ensembl:ENSP00000424571|ensembl:ENSP00000262464|uniprotkb:B4DU01|uniprotkb:Q59ES6 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:fbn2_human(display_long)|uniprotkb:FBN2(gene name)|psi-mi:FBN2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35556|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|interpro:IPR018097|ensembl:ENSG00000138829(gene)|ensembl:ENST00000262464(transcript)|ensembl:ENST00000508053(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|refseq:NP_001990.2 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:iqBnjHuy9kU3serIc5tPWGIDzUc9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P52701 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-395529|uniprotkb:O43706|uniprotkb:O43917|uniprotkb:Q8TCX4|uniprotkb:Q9BTB5|ensembl:ENSP00000234420|uniprotkb:B4DF41|uniprotkb:B4E3I4|uniprotkb:F5H2F9 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:msh6_human(display_long)|uniprotkb:MSH6(gene name)|psi-mi:MSH6(display_short)|uniprotkb:MutS-alpha 160 kDa subunit(gene name synonym)|uniprotkb:G/T mismatch-binding protein(gene name synonym)|uniprotkb:GTBP(gene name synonym)|uniprotkb:MutS protein homolog 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_000170.1|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006290"(pyrimidine dimer repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009411"(response to UV)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019899"(enzyme binding)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|mint:P52701|rcsb pdb:2GFU|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:6OQM|reactome:R-HSA-5358565|reactome:R-HSA-5632928|reactome:R-HSA-5632968|ensembl:ENSG00000116062(gene)|ensembl:ENST00000234420(transcript)|refseq:NP_001268421.1|refseq:NP_001268422.1|refseq:NP_001268423.1|dip:DIP-32972N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:YPpiWmh4fSjXapWgA/rXbMrLAGg9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q8N122 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1567928|uniprotkb:Q8N4V9|uniprotkb:Q8TB32|uniprotkb:Q9P2P3|uniprotkb:B2RN36|uniprotkb:C6KEF2|uniprotkb:F5H7J5|ensembl:ENSP00000307272 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rptor_human(display_long)|uniprotkb:"p150 target of rapamycin (TOR)-scaffold protein"(gene name synonym)|uniprotkb:RPTOR(gene name)|psi-mi:RPTOR(display_short)|uniprotkb:KIAA1303(gene name synonym)|uniprotkb:RAPTOR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001156506.1|refseq:NP_065812.1|dip:DIP-39482N|ensembl:ENSG00000141564(gene)|ensembl:ENST00000306801(transcript)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|mint:Q8N122|rcsb pdb:5H64|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6U62|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:BOvNcQXqn9hLPxAZeCZhKWbwgOk9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q96II8 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-8795942|uniprotkb:B4E0T7|intact:EBI-10963906|uniprotkb:Q9NT52|uniprotkb:Q96FP9|ensembl:ENSP00000393579 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:lrch3_human(display_long)|uniprotkb:LRCH3(gene name)|psi-mi:LRCH3(display_short)|uniprotkb:Leucine-rich repeat and calponin homology domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:XP_005269419.1|refseq:NP_116162.1|refseq:XP_006713854.1|ensembl:ENSG00000186001(gene)|ensembl:ENST00000425562(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032185"(septin cytoskeleton organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036872 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:hb9NKXgACuzQk1py0w1k4DcE0h09606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9BZQ6 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2556756|uniprotkb:B7ZLZ2|uniprotkb:Q9UFV7|uniprotkb:Q0VGM5|uniprotkb:B2RCH6|uniprotkb:Q9HCW1|uniprotkb:Q5TEZ0|uniprotkb:Q7L2Y5|ensembl:ENSP00000318147|intact:EBI-11137062 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:edem3_human(display_long)|uniprotkb:C1orf22(gene name synonym)|uniprotkb:EDEM3(gene name)|psi-mi:EDEM3(display_short)|uniprotkb:Alpha-1,2-mannosidase EDEM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_079467.3|ensembl:ENSG00000116406(gene)|ensembl:ENST00000318130(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR003137(Protease-associated PA)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR037322|interpro:IPR044674|reactome:R-HSA-901032|refseq:NP_001306889.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Y+n8Hhal53ri5I8jlKzXI6S8pk09606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9BWG4 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-744719|ensembl:ENSP00000270061|uniprotkb:Q9BWW5 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:ssbp4_human(display_long)|uniprotkb:SSBP4(gene name)|psi-mi:SSBP4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000130511(gene)|ensembl:ENST00000270061(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWG4|refseq:NP_001009998.1|refseq:NP_116016.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:c0T7Xjz4MbjSZpCzJlpGVFbFYy89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O60568 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-741582|uniprotkb:Q540C3|ensembl:ENSP00000223127|uniprotkb:B2R6W6 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:plod3_human(display_long)|uniprotkb:PLOD3(gene name)|psi-mi:PLOD3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000106397(gene)|ensembl:ENST00000223127(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005506"(iron ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0008104"(protein localization)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0021915"(neural tube development)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033823"(procollagen glucosyltransferase activity)|go:"GO:0042311"(vasodilation)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O60568|rcsb pdb:6FXK|rcsb pdb:6FXM|rcsb pdb:6FXR|rcsb pdb:6FXT|rcsb pdb:6FXX|rcsb pdb:6FXY|rcsb pdb:6TE3|rcsb pdb:6TEC|refseq:NP_001075.1|rcsb pdb:6TES|rcsb pdb:6TEU|rcsb pdb:6TEX|rcsb pdb:6TEZ|reactome:R-HSA-1650814|rcsb pdb:6WFV - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:dvfk+ko7squrB6c4AayW+fR8EnE9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P46939 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:metWqbqGtzonNZ1mgNjlFrenuI89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q7Z350 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723278 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q7z350_human(display_long)|uniprotkb:DKFZp686L0695(gene name)|psi-mi:DKFZp686L0695(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Wgmgo7q7QpfR0q6SXUHvzI/MrgA9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O75962-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723105 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:o75962-2(display_long)|uniprotkb:PTPRF-interacting protein(gene name synonym)|uniprotkb:TRIO(gene name)|psi-mi:TRIO(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:O75962-2(isoform-parent)|intact:EBI-718519(isoform-parent) - - isoform-comment:"Ref.5 (AAC34245) sequence differs from that shown due to frameshift." figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:05AfZy8zEQNMRmGeRjpSi39OeU09606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:H7BYD0 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723094|ensembl:ENSP00000368072 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:h7byd0_human(display_long)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000128609(gene)|ensembl:ENST00000378795(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0022904"(respiratory electron transport chain)|interpro:IPR006806(ETC complex I subunit) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:D3jg/Sebjo4sd9F1ZRPi8i1WZsg9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9NYU2-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-11019518 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9nyu2-2(display_long)|uniprotkb:UGGT1(gene name)|psi-mi:UGGT1(display_short)|uniprotkb:GT(gene name synonym)|uniprotkb:"UDP--Glc:glycoprotein glucosyltransferase"(gene name synonym)|uniprotkb:UDP-glucose ceramide glucosyltransferase-like 1(gene name synonym)|uniprotkb:UGCGL1(gene name synonym)|uniprotkb:UGGT(gene name synonym)|uniprotkb:UGT1(gene name synonym)|uniprotkb:UGTR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 intact:EBI-1056389(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:IlwHiRLmfwXG5TFTMzSZPc24Vj89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9UHV7 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394440|uniprotkb:O60334|uniprotkb:B2RU05|ensembl:ENSP00000380888 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med13_human(display_long)|uniprotkb:TRAP240(gene name synonym)|uniprotkb:MED13(gene name)|psi-mi:MED13(display_short)|uniprotkb:ARC250(gene name synonym)|uniprotkb:KIAA0593(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex component DRIP250(gene name synonym)|uniprotkb:Activator-recruited cofactor 250 kDa component(gene name synonym)|uniprotkb:THRAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_005112.2|ensembl:ENSG00000108510(gene)|ensembl:ENST00000397786(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR009401(TRAP240)|interpro:IPR041285|mint:Q9UHV7|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31468N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:ZNWwmsetsKLA56joRzRL0UKjq9Y9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P67775 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P49247 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:E9PF10 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-10966422|ensembl:ENSP00000422019 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pf10_human(display_long)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001265241.1|ensembl:ENSG00000113569(gene)|ensembl:ENST00000513532(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042537|interpro:IPR042538 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:MVzd8diq4txjpvuviCQJte4Qjgk9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q5JRI1 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723264|ensembl:ENSP00000363577 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q5jri1_human(display_long)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000188529(gene)|ensembl:ENST00000374453(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|refseq:NP_001287865.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:9OKUv5nxzwWhQfo4ypSoMGFv5rE9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q96EN8 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1220583|uniprotkb:Q53GP5|uniprotkb:Q8N3A4|uniprotkb:Q9NWM7|ensembl:ENSP00000261326 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:mocos_human(display_long)|uniprotkb:MOCOS(gene name)|psi-mi:MOCOS(display_short)|uniprotkb:Molybdenum cofactor sulfurtransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_060417.2|ensembl:ENSG00000075643(gene)|ensembl:ENST00000261326(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0008265"(Mo-molybdopterin cofactor sulfurase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032324"(molybdopterin cofactor biosynthetic process)|go:"GO:0043545"(molybdopterin cofactor metabolic process)|go:"GO:0102867"(molybdenum cofactor sulfurtransferase activity)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR005302(Molybdenum cofactor sulphurase, C-terminal)|interpro:IPR005303(MOSC, N-terminal beta barrel)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR028886|mint:Q96EN8|reactome:R-HSA-947581 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:c1HZVYnnbRSW3olxYNYmtb3S8a09606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P62487 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:H3BVG0 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723251|ensembl:ENSP00000458101 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:h3bvg0_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000102900(gene)|go:"GO:0005643"(nuclear pore)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR007231(Nucleoporin interacting component)|ensembl:ENST00000569842(transcript) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:zAL3KNPEvD5XxTlpSnHq1AU3hkk9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P19387 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q12933-4 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723245 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q12933-4(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:Q12933-4(isoform-parent)|intact:EBI-355744(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:GP+6S2ZJ8kDj5bX4LE/ffjXPkM89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:E9PJM3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723230|ensembl:ENSP00000431745 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pjm3_human(display_long)|uniprotkb:FBXO3(gene name)|psi-mi:FBXO3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000110429(gene)|ensembl:ENST00000534136(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007474(ApaG)|interpro:IPR018958|interpro:IPR028388|interpro:IPR036047|interpro:IPR036767|interpro:IPR037883 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Lj+01l0SOKqyfLbJyjRzuCeGQ8k9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:J3KTL8 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723217|ensembl:ENSP00000463049 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:j3ktl8_human(display_long)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000101596(gene)|ensembl:ENST00000577880(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0051276"(chromosome organization)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR038892 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:8Qfsi0+N9+sdGE6NQ7qCkxVAgZA9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P18583-10 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723204 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p18583-10(display_long)|uniprotkb:Bax antagonist selected in saccharomyces 1(gene name synonym)|uniprotkb:Negative regulatory element-binding protein(gene name synonym)|uniprotkb:Protein DBP-5(gene name synonym)|uniprotkb:SON3(gene name synonym)|uniprotkb:HSPC310(orf name)|uniprotkb:HSPC312(orf name)|uniprotkb:SON(gene name)|psi-mi:SON(display_short)|uniprotkb:C21orf50(gene name synonym)|uniprotkb:DBP5(gene name synonym)|uniprotkb:KIAA1019(gene name synonym)|uniprotkb:NREBP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:P18583-10(isoform-parent)|intact:EBI-1053513(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:q0PXEMygT1zEVWWQhs5OJVZvVSM9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P11047 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-714904|uniprotkb:Q5VYE7|ensembl:ENSP00000258341 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:lamc1_human(display_long)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:LAMC1(gene name)|psi-mi:LAMC1(display_short)|uniprotkb:LAMB2(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|mint:P11047|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9619665|go:"GO:0070062"(extracellular exosome)|refseq:NP_002284.3|ensembl:ENSG00000135862(gene)|ensembl:ENST00000258341(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007492"(endoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:2JMPODzaiqmTaLlmjdgvlv8e8+M9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P53396-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-16399011|ensembl:ENSP00000345398|ensembl:ENSP00000377474 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p53396-2(display_long)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000131473(gene)|ensembl:ENST00000353196(transcript)|ensembl:ENST00000393896(transcript)|intact:EBI-1042794(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:pBJJcwGUAn6Tyx0dgKPXQtcoLFE9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P35250-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-12936957|ensembl:ENSP00000275627 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p35250-2(display_long)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000049541(gene)|ensembl:ENST00000352131(transcript)|uniprotkb:P35250-2(isoform-parent)|intact:EBI-476409(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:lsI0SIBF2KE5ZZZ56qZXuWFCr249606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O43439-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723195|ensembl:ENSP00000380902|ensembl:ENSP00000433270 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:o43439-2(display_long)|uniprotkb:ETO homologous on chromosome 20(gene name synonym)|uniprotkb:MTG8-like protein(gene name synonym)|uniprotkb:MTG8-related protein 1(gene name synonym)|uniprotkb:Myeloid translocation-related protein 1(gene name synonym)|uniprotkb:p85(gene name synonym)|uniprotkb:EHT(isoform synonym)|uniprotkb:MTGR1a(isoform synonym)|uniprotkb:CBFA2T2(gene name)|psi-mi:CBFA2T2(display_short)|uniprotkb:EHT(gene name synonym)|uniprotkb:MTGR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000078699(gene)|ensembl:ENST00000397800(transcript)|ensembl:ENST00000492345(transcript)|uniprotkb:O43439-2(isoform-parent)|intact:EBI-748628(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:8xmgENrtFihsF6jVVN6HlpQXjVY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q5U5Q3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2864451|uniprotkb:Q9NZE3|uniprotkb:A1L022|ensembl:ENSP00000385610 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:mex3c_human(display_long)|uniprotkb:MEX3C(gene name)|psi-mi:MEX3C(display_short)|uniprotkb:RKHD2(gene name synonym)|uniprotkb:RNF194(gene name synonym)|uniprotkb:RING finger and KH domain-containing protein 2(gene name synonym)|uniprotkb:RING finger protein 194(gene name synonym)|uniprotkb:BM-013(orf name)|uniprotkb:RING-type E3 ubiquitin transferase MEX3C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_057710.3|ensembl:ENSG00000176624(gene)|ensembl:ENST00000406189(transcript)|go:"GO:0003415"(chondrocyte hypertrophy)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097009"(energy homeostasis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036612|rcsb pdb:5WWW|rcsb pdb:5WWX|rcsb pdb:5WWZ|rcsb pdb:5ZI6|reactome:R-HSA-983168 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:ZmQS1ZMrIF33uyR7VW2C4t9cyyk9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:E9PQR7 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723179|ensembl:ENSP00000434393 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pqr7_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000160948(gene)|ensembl:ENST00000531032(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:NOOGvmWpQDY4QA2RtcuFzTEn5W89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P22234 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q8NCN5 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-16769589|ensembl:ENSP00000288050|ensembl:ENSP00000457916|uniprotkb:A7E298|uniprotkb:A8K8Y7|uniprotkb:B3KSE1|uniprotkb:Q6AI20|uniprotkb:Q6AWC9 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:pdpr_human(display_long)|uniprotkb:PDPR(gene name)|psi-mi:PDPR(display_short)|uniprotkb:KIAA1990(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000090857(gene)|ensembl:ENST00000288050(transcript)|ensembl:ENST00000568530(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR001763(Rhodanese-like)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR006222(Glycine cleavage T-protein, N-terminal)|interpro:IPR013977(Glycine cleavage T-protein, C-terminal barrel)|interpro:IPR027266|interpro:IPR029043|interpro:IPR032503|interpro:IPR036188|reactome:R-HSA-204174|refseq:NP_001309046.1|refseq:NP_060460.4|refseq:XP_005256072.1|refseq:XP_005256073.1|refseq:XP_016878876.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:jKDbjPDs6wBeHVsTm8j9cZj4yAA9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:K7ENR6 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723169|ensembl:ENSP00000467060 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:k7enr6_human(display_long)|uniprotkb:PSMG2(gene name)|psi-mi:PSMG2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000128789(gene)|ensembl:ENST00000590217(transcript)|interpro:IPR016562(Uncharacterised conserved protein UCP010044)|interpro:IPR019151|interpro:IPR038389 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Ht4aR0SgREXzpSCXJt6qYxB7Ja89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P39656 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P61964 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9Y266 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-357298|ensembl:ENSP00000319664|uniprotkb:Q5QP31|uniprotkb:Q5QP35|uniprotkb:Q9H0N2|uniprotkb:Q9Y2B6|intact:EBI-2555945 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:nudc_human(display_long)|uniprotkb:NUDC(gene name)|psi-mi:NUDC(display_short)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000090273(gene)|ensembl:ENST00000321265(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:Q9Y266|rcsb pdb:3QOR|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0007080"(mitotic metaphase plate congression)|reactome:R-HSA-9696270|refseq:NP_006591.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:e1Q+/+VhG73ljCc3+ibG+RZNQUM9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q5SRQ3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723124|ensembl:ENSP00000365040|ensembl:ENSP00000372923|ensembl:ENSP00000389767|ensembl:ENSP00000390345|ensembl:ENSP00000392194|ensembl:ENSP00000407844|ensembl:ENSP00000407864|ensembl:ENSP00000477593|ensembl:ENSP00000478227|ensembl:ENSP00000480787|ensembl:ENSP00000482951|ensembl:ENSP00000484115|ensembl:ENSP00000484705 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q5srq3_human(display_long)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CSNK2B-LY6G5B-1181(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000206406(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENSG00000258543(gene)|ensembl:ENSG00000258589(gene)|ensembl:ENSG00000263020(gene)|ensembl:ENST00000375880(transcript)|ensembl:ENST00000383431(transcript)|ensembl:ENST00000413083(transcript)|ensembl:ENST00000416194(transcript)|ensembl:ENST00000437010(transcript)|ensembl:ENST00000443952(transcript)|ensembl:ENST00000457089(transcript)|ensembl:ENST00000614071(transcript)|ensembl:ENST00000614974(transcript)|ensembl:ENST00000620322(transcript)|ensembl:ENST00000620798(transcript)|ensembl:ENST00000621203(transcript)|ensembl:ENST00000622139(transcript)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019887"(protein kinase regulator activity)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:LfqUXxpolbDZR5TPgM6hs3FMV1k9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9H6R7 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-346906|uniprotkb:D6W532|uniprotkb:Q8IYK0|uniprotkb:Q9HBP5|ensembl:ENSP00000295148 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:wdcp_human(display_long)|uniprotkb:WDCP(gene name)|psi-mi:WDCP(display_short)|uniprotkb:C2orf44(gene name synonym)|uniprotkb:PP384(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001135791.1|refseq:NP_079479.1|ensembl:ENSG00000163026(gene)|ensembl:ENST00000295148(transcript)|go:"GO:0019900"(kinase binding)|go:"GO:0051259"(protein complex oligomerization)|interpro:IPR028041|mint:Q9H6R7 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:qT8Zfifj+1U5HvWjtXjKTiVj1OA9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P62310 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q96F44-3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723118 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q96f44-3(display_long)|uniprotkb:TRIM11(gene name)|psi-mi:TRIM11(display_short)|uniprotkb:RNF92(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:Q96F44-3(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:OO/KqJmgSVSQM7nAM/NMY7+Nfzk9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q15024 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q86WJ1-3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723112|ensembl:ENSP00000358263 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q86wj1-3(display_long)|uniprotkb:CHD1L(gene name)|psi-mi:CHD1L(display_short)|uniprotkb:ALC1(gene name synonym)|uniprotkb:Amplified in liver cancer protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:Q86WJ1-3(isoform-parent)|intact:EBI-2340020(isoform-parent)|ensembl:ENSG00000131778(gene)|ensembl:ENST00000369259(transcript) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:hHo0jfnG9+9fIQXFOzJU1EwW0so9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q96JB3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-726282|uniprotkb:Q504T6|uniprotkb:Q96KR3|uniprotkb:Q9NSM9|uniprotkb:Q9UPX9|ensembl:ENSP00000384889|ensembl:ENSP00000385319|ensembl:ENSP00000387757 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:hic2_human(display_long)|uniprotkb:Hic-3(gene name synonym)|uniprotkb:HIC1-related gene on chromosome 22 protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 30(gene name synonym)|uniprotkb:HIC2(gene name)|psi-mi:HIC2(display_short)|uniprotkb:HRG22(gene name synonym)|uniprotkb:KIAA1020(gene name synonym)|uniprotkb:ZBTB30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_055909.2|refseq:XP_016884158.1|refseq:XP_011528309.1|refseq:XP_011528310.1|refseq:XP_011528311.1|refseq:XP_011528312.1|ensembl:ENSG00000169635(gene)|ensembl:ENST00000407464(transcript)|ensembl:ENST00000407598(transcript)|ensembl:ENST00000443632(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:bfyBMyJ4q1mzy+GNgOZvfdk+Gjo9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:F2Z3J2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723083|ensembl:ENSP00000435773|ensembl:ENSP00000487480 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:f2z3j2_human(display_long)|uniprotkb:PSMD5(gene name)|psi-mi:PSMD5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000095261(gene)|ensembl:ENST00000476949(transcript)|ensembl:ENST00000625444(transcript)|go:"GO:0043248"(proteasome assembly)|interpro:IPR019538 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:PBKIS8d76SfI3ZUbciwXHbB641o9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P53621 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P48553 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-6160572|uniprotkb:Q86SI7|uniprotkb:Q3MIR2|uniprotkb:Q9UMD4|uniprotkb:Q9Y4L3|ensembl:ENSP00000291574 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:tpc10_human(display_long)|uniprotkb:TRAPPC10(gene name)|psi-mi:TRAPPC10(display_short)|uniprotkb:EHOC1(gene name synonym)|uniprotkb:TMEM1(gene name synonym)|uniprotkb:Epilepsy holoprosencephaly candidate 1 protein(gene name synonym)|uniprotkb:Protein GT334(gene name synonym)|uniprotkb:Trafficking protein particle complex subunit TMEM1(gene name synonym)|uniprotkb:Transport protein particle subunit TMEM1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:XP_016855323.1|refseq:NP_003265.3|dip:DIP-48281N|ensembl:ENSG00000160218(gene)|ensembl:ENST00000291574(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:1990071"(TRAPPII protein complex)|interpro:IPR022233|reactome:R-HSA-204005|reactome:R-HSA-8876198 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:VUosZh02L+11PPUoR+v8GHPPFZI9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q96S15 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-746424|uniprotkb:Q96GC7|uniprotkb:Q9H0B7|uniprotkb:A2IDB8|uniprotkb:D3DU59|ensembl:ENSP00000293883|intact:EBI-11086802 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:wdr24_human(display_long)|uniprotkb:WDR24(gene name)|psi-mi:WDR24(display_short)|uniprotkb:C16orf21(gene name synonym)|uniprotkb:WD repeat-containing protein 24(gene name synonym)|uniprotkb:JFP7(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_115635.1|ensembl:ENSG00000127580(gene)|ensembl:ENST00000293883(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061700"(GATOR2 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037590|reactome:R-HSA-9639288|dip:DIP-53812N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:t4jmiY8uryt3X3y5QUGYRMGFpXg9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O75323 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-307133|uniprotkb:O43801|uniprotkb:Q53X96|uniprotkb:C9IYJ3|ensembl:ENSP00000313050 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:nips2_human(display_long)|uniprotkb:NIPSNAP2(gene name)|psi-mi:NIPSNAP2(display_short)|uniprotkb:GBAS(gene name synonym)|uniprotkb:Glioblastoma-amplified sequence(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001189398.1|refseq:NP_001474.1|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:O75323|reactome:R-HSA-9013407|reactome:R-HSA-9013409|ensembl:ENSG00000146729(gene)|ensembl:ENST00000322090(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|dip:DIP-33564N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:sfBQGdtSVoH21kBu/Bz9x8x3KWU9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 intact:EBI-20723073 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 - psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:f5gx77_human(display_short)|psi-mi:EBI-20723073(display_long)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:F5GX77(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:j858NUAaCiBwT1mX5R/FmpOECI49606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q96LD4 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2130423|uniprotkb:Q96GU5|uniprotkb:Q9BRN7|uniprotkb:Q96AD0|intact:EBI-28987808|ensembl:ENSP00000254816 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:tri47_human(display_long)|uniprotkb:TRIM47(gene name)|psi-mi:TRIM47(display_short)|uniprotkb:GOA(gene name synonym)|uniprotkb:RNF100(gene name synonym)|uniprotkb:Gene overexpressed in astrocytoma protein(gene name synonym)|uniprotkb:RING finger protein 100(gene name synonym)|uniprotkb:Tripartite motif-containing protein 47(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_258411.2|ensembl:ENSP00000254816|refseq:XP_005257844.1|refseq:XP_005257845.1|ensembl:ENSG00000132481(gene)|ensembl:ENST00000254816(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042780|interpro:IPR043136|mint:Q96LD4 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:F8KSNivuNkLAEFW/DrYsMu5ICRk9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:E5RHG8 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-10977654|ensembl:ENSP00000429789 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e5rhg8_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000154582(gene)|ensembl:ENST00000519082(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:bDY6n7TGKdEkMqC/5h4tvcb7L6Y9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q8IV48 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-5459222|uniprotkb:A8K4U7|uniprotkb:Q9NSX3|ensembl:ENSP00000250263|ensembl:ENSP00000430190 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:eri1_human(display_long)|uniprotkb:ERI1(gene name)|psi-mi:ERI1(display_short)|uniprotkb:3'EXO(gene name synonym)|uniprotkb:THEX1(gene name synonym)|uniprotkb:3'-5' exonuclease ERI1(gene name synonym)|uniprotkb:Eri-1 homolog(gene name synonym)|uniprotkb:Histone mRNA 3'-end-specific exoribonuclease(gene name synonym)|uniprotkb:Histone mRNA 3'-exonuclease 1(gene name synonym)|uniprotkb:Protein 3'hExo(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_699163.2|dip:DIP-61409N|ensembl:ENSG00000104626(gene)|ensembl:ENST00000250263(transcript)|ensembl:ENST00000519292(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0019843"(rRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031125"(rRNA 3'-end processing)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR036361|interpro:IPR036397|rcsb pdb:1W0H|rcsb pdb:1ZBH|rcsb pdb:1ZBU|rcsb pdb:4L8R|rcsb pdb:4QOZ|reactome:R-HSA-6791226 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:wtuZZZVatZWPvuO1g3sT/FJsBPE9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:A6NHL2-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723068 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:a6nhl2-2(display_long)|uniprotkb:TUBAL3(gene name)|psi-mi:TUBAL3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:A6NHL2-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:svCnlapBKXSlfZEO5h58Pz3Q5gY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9Y5V3-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-16812862 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9y5v32(display_long)|uniprotkb:PP2250(orf name)|uniprotkb:PRO2292(orf name)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:Q9Y5V3-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:BMWcQEWXLa1tlUMwjwBL34RRH9E9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:B4DDV3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-10978784 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:b4ddv3_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001307987.1|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR029035|go:"GO:0016740"(transferase activity)|go:"GO:0070403"(NAD+ binding) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:u5DyfcU/8nlpFfSEbKM+RSgpcMU9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O43318-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-358700|ensembl:ENSP00000358338|intact:EBI-8504523|intact:MINT-88577|intact:EBI-8504565|intact:EBI-8504760|intact:EBI-8504490 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:o43318-2(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 intact:EBI-358684(m3k7_human)|ensembl:ENSG00000135341(gene)|ensembl:ENST00000369332(transcript)|uniprotkb:O43318-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:cbvDXk0gd0dt+l8eJxhfBYKPaQE9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q93074-3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-11030781|ensembl:ENSP00000363215 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q93074-3(display_long)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000184634(gene)|ensembl:ENST00000374102(transcript)|intact:EBI-394357(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:q2s3nKB73bdD0sQiG+wPfax0k4c9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9ULX6-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723060 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9ulx6-2(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:NAKAP(gene name synonym)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:HRIHFB2018(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:Q9ULX6-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:5ZeJwkHHE2X1idcSPZbPl3glm1Y9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O15027 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-357515|intact:EBI-1384174|uniprotkb:A1YCA4|uniprotkb:Q5SXP0|uniprotkb:Q5SXP1|uniprotkb:Q8N347|uniprotkb:Q96HP1|uniprotkb:J3KNL6|uniprotkb:Q4G0D7|intact:EBI-28968206|ensembl:ENSP00000325827|intact:EBI-10967582|intact:EBI-21024388 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:sc16a_human(display_long)|uniprotkb:KIAA0310(gene name synonym)|uniprotkb:SEC16(gene name synonym)|uniprotkb:SEC16L(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:SEC16A(gene name)|psi-mi:SEC16A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:XP_011517562.1|refseq:XP_005266191.1|refseq:XP_011517548.1|refseq:XP_011517549.1|refseq:XP_011517550.1|refseq:XP_011517557.1|refseq:XP_011517559.1|refseq:XP_011517561.1|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:O15027|reactome:R-HSA-204005|ensembl:ENSG00000148396(gene)|ensembl:ENST00000313050(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031090"(organelle membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensembl:ENSP00000325827|refseq:NP_055681.1|refseq:XP_011517554.1|refseq:NP_001263347.1|dip:DIP-27588N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:yB65QJbL+WBjtWO5UXAx2DCRbwI9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:E9PNW8 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723046|ensembl:ENSP00000437111 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pnw8_human(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000197601(gene)|ensembl:ENST00000532701(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR036291 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:+JHdLhoNtynywYk+gSS7KHYJqQg9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P04049 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-365996|uniprotkb:B0LPH8|uniprotkb:Q15278|uniprotkb:Q9UC20|ensembl:ENSP00000251849|uniprotkb:B2R5N3 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:raf1_human(display_long)|uniprotkb:RAF1(gene name)|psi-mi:RAF1(display_short)|uniprotkb:RAF(gene name synonym)|uniprotkb:Proto-oncogene c-RAF(gene name synonym)|uniprotkb:Raf-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 rcsb pdb:3IQV|rcsb pdb:3KUC|rcsb pdb:3KUD|rcsb pdb:3NKX|rcsb pdb:3O8I|rcsb pdb:3OMV|rcsb pdb:4FJ3|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4IEA|rcsb pdb:4IHL|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6VJJ|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6XI7|ensembl:ENSG00000132155(gene)|ensembl:ENST00000251849(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007507"(heart development)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0060324"(face development)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P04049|rcsb pdb:1C1Y|rcsb pdb:1FAQ|rcsb pdb:1FAR|rcsb pdb:1GUA|rcsb pdb:1RFA|rcsb pdb:3CU8|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:7JHP|reactome:R-HSA-2672351|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-5621575|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|refseq:NP_002871.1|refseq:XP_011532276.1|refseq:XP_005265412.1|dip:DIP-1048N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:1WOAPuzcZdMoq9hyFD/qr4Tz7049606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9HCK5 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2269696|uniprotkb:A7MD27|ensembl:ENSP00000362306 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:ago4_human(display_long)|uniprotkb:AGO4(gene name)|psi-mi:AGO4(display_short)|uniprotkb:Argonaute RISC catalytic component 4(gene name synonym)|uniprotkb:EIF2C4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 4(gene name synonym)|uniprotkb:KIAA1567(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_060099.2|ensembl:ENSG00000134698(gene)|ensembl:ENST00000373210(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0008584"(male gonad development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070578"(RISC-loading complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028604|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|rcsb pdb:6OON|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Trb+nRiEAUNwHDgrcv70Uz20YDs9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P27635 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9H0J9 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-765907|uniprotkb:Q9H610|uniprotkb:Q9NP36|uniprotkb:Q9NTI3|ensembl:ENSP00000263549 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:par12_human(display_long)|uniprotkb:Zinc finger CCCH domain-containing protein 1(gene name synonym)|uniprotkb:PARP12(gene name)|psi-mi:PARP12(display_short)|uniprotkb:ZC3HDC1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 12(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_073587.1|ensembl:ENSG00000059378(gene)|ensembl:ENST00000263549(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|rcsb pdb:2PQF|rcsb pdb:6V3W - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:JYAGjPHJuEyh/yQE9vTfNOwXgNo9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9NVC6 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:C9J0K6 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-11033494|ensembl:ENSP00000418512 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:c9j0k6_human(display_long)|uniprotkb:SRI(gene name)|psi-mi:SRI(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:XP_011514830.1|ensembl:ENSG00000075142(gene)|ensembl:ENST00000490437(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:leqocEtCEYrbVGCmfEaRzTxk4LI9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P62993 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-401755|ensembl:ENSP00000339007|uniprotkb:P29354|uniprotkb:Q14450|uniprotkb:Q63057|uniprotkb:Q63059|ensembl:ENSP00000376345|ensembl:ENSP00000376347|ensembl:ENSP00000496913 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:grb2_human(display_long)|uniprotkb:GRB2(gene name)|psi-mi:GRB2(display_short)|uniprotkb:ASH(gene name synonym)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)|uniprotkb:Protein Ash(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000177885(gene)|refseq:NP_002077.1|refseq:NP_987102.1|ensembl:ENST00000316804(transcript)|ensembl:ENST00000392562(transcript)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|ensembl:ENST00000392564(transcript)|ensembl:ENST00000648046(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0007568"(aging)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0012506"(vesicle membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070436"(Grb2-EGFR complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|mint:P62993|rcsb pdb:1AZE|rcsb pdb:1BM2|rcsb pdb:1BMB|rcsb pdb:1CJ1|rcsb pdb:1FHS|rcsb pdb:1FYR|rcsb pdb:1GCQ|rcsb pdb:1GFC|rcsb pdb:1GFD|rcsb pdb:1GHU|rcsb pdb:1GRI|rcsb pdb:1IO6|rcsb pdb:1JYQ|rcsb pdb:1JYR|rcsb pdb:1JYU|rcsb pdb:1QG1|rcsb pdb:1TZE|rcsb pdb:1X0N|rcsb pdb:1ZFP|rcsb pdb:2AOA|rcsb pdb:2AOB|rcsb pdb:2H46|rcsb pdb:2H5K|rcsb pdb:2HUW|rcsb pdb:2VVK|rcsb pdb:2VWF|rcsb pdb:2W0Z|rcsb pdb:3C7I|rcsb pdb:3IMD|rcsb pdb:3IMJ|rcsb pdb:3IN7|rcsb pdb:3IN8|rcsb pdb:3KFJ|rcsb pdb:3MXC|rcsb pdb:3N7Y|rcsb pdb:3N84|rcsb pdb:3N8M|rcsb pdb:3OV1|rcsb pdb:3OVE|rcsb pdb:3MXY|rcsb pdb:3S8L|rcsb pdb:3S8N|rcsb pdb:3S8O|rcsb pdb:3WA4|rcsb pdb:4P9V|rcsb pdb:4P9Z|rcsb pdb:5CDW|rcsb pdb:6ICG|rcsb pdb:6ICH|rcsb pdb:6SDF|rcsb pdb:6VK2|rcsb pdb:6WM1|rcsb pdb:6WO2|reactome:R-HSA-109704|reactome:R-HSA-112412|reactome:R-HSA-1236382|reactome:R-HSA-1250196|reactome:R-HSA-1250347|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-167044|reactome:R-HSA-179812|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2029482|reactome:R-HSA-210993|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2428933|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-354194|reactome:R-HSA-375165|reactome:R-HSA-388841|reactome:R-HSA-389359|reactome:R-HSA-391160|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654688|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5663213|reactome:R-HSA-5673001|reactome:R-HSA-6807004|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-74751|reactome:R-HSA-8851805|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8865999|reactome:R-HSA-8875360|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-8983432|reactome:R-HSA-9026519|reactome:R-HSA-9027284|reactome:R-HSA-9028335|reactome:R-HSA-5654689|reactome:R-HSA-9028731|reactome:R-HSA-9034864|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9607240|reactome:R-HSA-9634285|reactome:R-HSA-9645135|reactome:R-HSA-9664422|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|dip:DIP-29229N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:SLnslQ7NHbnuK06nMVuRvJpoOA49606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P55268 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2529769|uniprotkb:Q16321|ensembl:ENSP00000307156|ensembl:ENSP00000388325 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:lamb2_human(display_long)|uniprotkb:Laminin-4 subunit beta(gene name synonym)|uniprotkb:Laminin-7 subunit beta(gene name synonym)|uniprotkb:Laminin-9 subunit beta(gene name synonym)|uniprotkb:Laminin-11 subunit beta(gene name synonym)|uniprotkb:Laminin-14 subunit beta(gene name synonym)|uniprotkb:Laminin-15 subunit beta(gene name synonym)|uniprotkb:S-laminin subunit beta(gene name synonym)|uniprotkb:LAMB2(gene name)|psi-mi:LAMB2(display_short)|uniprotkb:LAMS(gene name synonym)|uniprotkb:Laminin-3 subunit beta(gene name synonym)|uniprotkb:Laminin B1s chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000172037(gene)|ensembl:ENST00000305544(transcript)|ensembl:ENST00000418109(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005608"(laminin-3 complex)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014002"(astrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016477"(cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043256"(laminin complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0048677"(axon extension involved in regeneration)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0072249"(metanephric glomerular visceral epithelial cell development)|go:"GO:0072274"(metanephric glomerular basement membrane development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P55268|reactome:R-HSA-3000157|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-3000171|refseq:NP_002283.3|refseq:XP_005265184.1|dip:DIP-42106N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:LY1lt2hyTcFN+x4GtvfzufChDF89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q63HN8 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P10909-4 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-4322678 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p10909-4(display_long)|uniprotkb:nCLU(isoform synonym)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:Sulfated glycoprotein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 intact:EBI-1104674(isoform-parent) - - isoform-comment:"Minor isoform that has been detected in a breast cancer cell line, but not in any other tissues or cell lines (Ref.29). Not glycosylated. Not detected in unstressed cells. Detectable at low level in stressed cells (Ref.3)." figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:5gthvEHR2f3sI/kC6sU19M/DBKc9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q15750 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-358643|uniprotkb:Q2PP09|intact:EBI-3959873|uniprotkb:Q8IZW2|ensembl:ENSP00000216160 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:tab1_human(display_long)|uniprotkb:TAB1(gene name)|psi-mi:TAB1(display_short)|uniprotkb:MAP3K7IP1(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_006107.1|refseq:NP_705717.1|ensembl:ENSP00000216160|ensembl:ENST00000331454|ensembl:ENSP00000333049|go:"GO:0003279"(cardiac septum development)|rcsb pdb:7NTI|go:"GO:0003007"(heart morphogenesis)|ensembl:ENSG00000100324(gene)|ensembl:ENST00000216160(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0060976"(coronary vasculature development)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q15750|rcsb pdb:2J4O|rcsb pdb:2POM|rcsb pdb:2POP|rcsb pdb:2YDS|rcsb pdb:2YIY|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4GS6|rcsb pdb:4KA3|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5DIY|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5V5N|rcsb pdb:5VVU|rcsb pdb:7NTH|reactome:R-HSA-168638|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27524N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:28+bzs6bpXJTun4XukxC/7oAYSs9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q5VY93 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723039|ensembl:ENSP00000357298 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q5vy93_human(display_long)|uniprotkb:ARHGEF2(gene name)|psi-mi:ARHGEF2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000116584(gene)|ensembl:ENST00000368315(transcript) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:qZk8+vo2v33XhlpcRL6oTcBWlvQ9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:C9JEV9 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723026|ensembl:ENSP00000396060 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:c9jev9_human(display_long)|uniprotkb:CPSF4(gene name)|psi-mi:CPSF4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000160917(gene)|ensembl:ENST00000451876(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036855|interpro:IPR036875 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:GxMG8IUKj8dIQfGKHZKN6wLKo6U9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q15648 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q32P28 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-396328|uniprotkb:Q96SK8|uniprotkb:Q7KZR4|uniprotkb:Q96BR8|uniprotkb:Q96SL5|uniprotkb:Q96SN3|uniprotkb:Q9H6K3|uniprotkb:Q9HC86|uniprotkb:Q9HC87|intact:EBI-2555416|ensembl:ENSP00000296388 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p3h1_human(display_long)|uniprotkb:P3H1(gene name)|psi-mi:P3H1(display_short)|uniprotkb:GROS1(gene name synonym)|uniprotkb:Growth suppressor 1(gene name synonym)|uniprotkb:LEPRE1(gene name synonym)|uniprotkb:Leucine- and proline-enriched proteoglycan 1(gene name synonym)|uniprotkb:PSEC0109(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001139761.1|refseq:NP_001230175.1|refseq:NP_071751.3|ensembl:ENSG00000117385(gene)|ensembl:ENST00000296388(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0019797"(procollagen-proline 3-dioxygenase activity)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901874"(negative regulation of post-translational protein modification)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR039575|interpro:IPR039837|mint:Q32P28|reactome:R-HSA-1650814 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:L3euuYyawz69NXv4u6baW/ceVdU9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:M0R0W6 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723006|ensembl:ENSP00000471497 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:m0r0w6_human(display_long)|uniprotkb:AXL(gene name)|psi-mi:AXL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000167601(gene)|ensembl:ENST00000593513(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036116|refseq:NP_001265528.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:8tiNeTBkIcDSEqUfqEcxZq+jE049606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:D6R938 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722987|ensembl:ENSP00000423677 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:d6r938_human(display_long)|uniprotkb:CAMK2D(gene name)|psi-mi:CAMK2D(display_short)|uniprotkb:hCG_22679(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000145349(gene)|ensembl:ENST00000514328(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|refseq:NP_001308503.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:q1yS9I1HDEPTopAGWNwPHPPI7zA9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:J3KS22 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722976|ensembl:ENSP00000462272 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:j3ks22_human(display_long)|uniprotkb:DCXR(gene name)|psi-mi:DCXR(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000169738(gene)|ensembl:ENST00000582900(transcript)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Y+9np+7O/eXpBdjvfTWilA+zh2Q9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:E9PQ57 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722960|ensembl:ENSP00000432609 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pq57_human(display_long)|uniprotkb:RAE1(gene name)|psi-mi:RAE1(display_short)|uniprotkb:mRNA export factor(gene name synonym)|uniprotkb:mRNA-associated protein mrnp 41(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000101146(gene)|ensembl:ENST00000527947(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037631 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:hpggnE+7y064td8Yo38J0+d4r4s9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q8IZH2-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-10965083|ensembl:ENSP00000376707 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q8izh2-2(display_long)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000114127(gene)|ensembl:ENST00000392981(transcript)|intact:EBI-372406(isoform-parent)|uniprotkb:Q8IZH2-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:E7g0flI0E0BQBTcMcbjByo6F/eQ9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q5TEE2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722947|ensembl:ENSP00000407859 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q5tee2_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000116478(gene)|ensembl:ENST00000428704(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:rf7F3YIXN1vwbLsggYFK6a6CFxM9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:E9PE19 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722923|ensembl:ENSP00000343837 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pe19_human(display_long)|uniprotkb:BPTF(gene name)|psi-mi:BPTF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000171634(gene)|ensembl:ENST00000342579(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016589"(NURF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR038028 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:qHAC3A29HFPsXe9mAXPVFakEJJs9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O15230 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-725060|uniprotkb:Q8WZA7|uniprotkb:Q9H1P1|uniprotkb:Q8TDF8|uniprotkb:Q5U4N9|ensembl:ENSP00000252999 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:lama5_human(display_long)|uniprotkb:LAMA5(gene name)|psi-mi:LAMA5(display_short)|uniprotkb:KIAA0533(gene name synonym)|uniprotkb:KIAA1907(gene name synonym)|uniprotkb:Laminin-10 subunit alpha(gene name synonym)|uniprotkb:Laminin-11 subunit alpha(gene name synonym)|uniprotkb:Laminin-15 subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_005551.3|ensembl:ENSG00000130702(gene)|ensembl:ENST00000252999(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001942"(hair follicle development)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005610"(laminin-5 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016477"(cell migration)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|mint:O15230|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-6785807|reactome:R-HSA-8874081 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:rSTl5zwwQKcbd20buKGffFtl3jI9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q6DKJ4 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1055389|uniprotkb:Q3SWW6|uniprotkb:Q6P3U6|uniprotkb:Q9H9Q1|uniprotkb:B4DXQ0|uniprotkb:Q7L4C6|uniprotkb:D3DTH2|ensembl:ENSP00000337443 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:nxn_human(display_long)|uniprotkb:NXN(gene name)|psi-mi:NXN(display_short)|uniprotkb:NRX(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_071908.2|refseq:NP_001192248.1|ensembl:ENST00000336868(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0072359"(circulatory system development)|interpro:IPR012336(Thioredoxin-like fold)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041861|mint:Q6DKJ4|ensembl:ENSG00000167693(gene) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:xQsuChT9r8OMThUdFAfhMknlhzU9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O95864 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-11337838|uniprotkb:A8K2M6|uniprotkb:Q6MZQ7|uniprotkb:Q9H3G3|uniprotkb:Q9Y3X4|uniprotkb:B7Z634|uniprotkb:Q96SV8|uniprotkb:Q96H07|ensembl:ENSP00000278840 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:fads2_human(display_long)|uniprotkb:Fatty acid desaturase 2(gene name synonym)|uniprotkb:FADS2(gene name)|psi-mi:FADS2(display_short)|uniprotkb:"Delta(6) fatty acid desaturase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001268430.1|refseq:NP_001268431.1|refseq:NP_004256.1|ensembl:ENSG00000134824(gene)|ensembl:ENST00000278840(transcript)|go:"GO:0004768"(stearoyl-CoA 9-desaturase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006636"(unsaturated fatty acid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016213"(linoleoyl-CoA desaturase activity)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043651"(linoleic acid metabolic process)|interpro:IPR001199(Cytochrome b5)|interpro:IPR005804(Fatty acid desaturase, type 1)|interpro:IPR012171(Fatty acid/sphingolipid desaturase)|interpro:IPR036400|mint:O95864|reactome:R-HSA-2046105|reactome:R-HSA-2046106 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:xyJ9VBTFjemwT3LQSM4bdikd4Zk9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:H7BY36 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722907|ensembl:ENSP00000353204 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:h7by36_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000182944(gene)|ensembl:ENST00000360091(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:ebqFOBv0lL2CtPEBpnrWbCMiNZs9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O43865 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2371423|uniprotkb:Q2TAJ6|uniprotkb:Q502W8|uniprotkb:Q5VSM0|uniprotkb:Q6P171|uniprotkb:Q96PK4|uniprotkb:Q9UG84|uniprotkb:B4E168|ensembl:ENSP00000358814 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:sahh2_human(display_long)|uniprotkb:AHCYL1(gene name)|psi-mi:AHCYL1(display_short)|uniprotkb:DCAL(gene name synonym)|uniprotkb:XPVKONA(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:DC-expressed AHCY-like molecule(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:"IP(3)Rs binding protein released with IP(3)"(gene name synonym)|uniprotkb:IRBIT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001229602.1|refseq:NP_001229603.1|refseq:NP_001229604.1|refseq:NP_001229605.1|refseq:NP_006612.2|ensembl:ENSG00000168710(gene)|ensembl:ENST00000369799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:O43865|rcsb pdb:3MTG|reactome:R-HSA-112043|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:uwZ+P9SdKadoVn01p/b8qHp6egk9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O60244 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P23142-3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722901|ensembl:ENSP00000393812 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p23142-3(display_long)|uniprotkb:FBLN1(gene name)|psi-mi:FBLN1(display_short)|uniprotkb:PP213(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000077942(gene)|ensembl:ENST00000442170(transcript)|uniprotkb:P23142-3(isoform-parent)|intact:EBI-726652(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:LlNjk4lysFMyAtlGZJ3zW2tmXs89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:H0YMM5 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722888|ensembl:ENSP00000453667 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:h0ymm5_human(display_long)|uniprotkb:DUT(gene name)|psi-mi:DUT(display_short)|uniprotkb:dUTP pyrophosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000128951(gene)|ensembl:ENST00000559935(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0046081"(dUTP catabolic process)|interpro:IPR008181(DeoxyUTP pyrophosphatase subfamily 1)|interpro:IPR029054|interpro:IPR033704|interpro:IPR036157 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:n75Ry9ExSL6lAdXiD+p/U8ubWcg9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:D6RG16 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722881|ensembl:ENSP00000426460 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:d6rg16_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000120725(gene)|ensembl:ENST00000505830(transcript) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Mmc1mcndcJysEJi4ERXbo3kLEDw9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P30153 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9HAV7 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P37802 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1056740|intact:EBI-2825986|uniprotkb:Q5JRQ6|uniprotkb:Q5JRQ7|uniprotkb:Q9BUH5|uniprotkb:Q9H4P0|uniprotkb:Q6FGI1|uniprotkb:E9KL39|ensembl:ENSP00000357075|ensembl:ENSP00000357077 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:tagl2_human(display_long)|uniprotkb:TAGLN2(gene name)|psi-mi:TAGLN2(display_short)|uniprotkb:KIAA0120(gene name synonym)|uniprotkb:SM22-alpha homolog(gene name synonym)|uniprotkb:CDABP0035(orf name)|uniprotkb:Epididymis tissue protein Li 7e(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_003555.1|refseq:NP_001264152.1|refseq:NP_001264153.1|ensembl:ENSG00000158710(gene)|ensembl:ENST00000320307(transcript)|ensembl:ENST00000368097(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031982"(vesicle)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000557(Calponin repeat)|interpro:IPR001061("Transgelin (SM22-alpha)")|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|mint:P37802|rcsb pdb:1WYM|reactome:R-HSA-114608 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:JxbMK5SbZWQd+XA9iYc/xuNaVQc9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q13951 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-718750|uniprotkb:Q13124|uniprotkb:Q9HCT2|uniprotkb:A8K347|ensembl:ENSP00000290858 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:pebb_human(display_long)|uniprotkb:Polyomavirus enhancer-binding protein 2 beta subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 subunit beta(gene name synonym)|uniprotkb:SL3/AKV core-binding factor beta subunit(gene name synonym)|uniprotkb:CBFB(gene name)|psi-mi:CBFB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001746.1|refseq:NP_074036.1|dip:DIP-36772N|ensembl:ENSG00000067955(gene)|ensembl:ENST00000290858(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR003417(Core binding factor, beta subunit)|interpro:IPR036552|mint:Q13951|rcsb pdb:1CL3|rcsb pdb:1E50|rcsb pdb:1H9D|rcsb pdb:4N9F|rcsb pdb:6NIL|rcsb pdb:6P59|rcsb pdb:6VGD|rcsb pdb:6VGE|rcsb pdb:6VGG|reactome:R-HSA-8877330|reactome:R-HSA-8878166|reactome:R-HSA-8931987|reactome:R-HSA-8934593|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030099"(myeloid cell differentiation)|reactome:R-HSA-8935964|reactome:R-HSA-8936459|reactome:R-HSA-8941332|reactome:R-HSA-8941333|reactome:R-HSA-8941858|reactome:R-HSA-8949275|reactome:R-HSA-8951911|reactome:R-HSA-8951936|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-8939236|reactome:R-HSA-8939242|reactome:R-HSA-8939243|reactome:R-HSA-8939245|reactome:R-HSA-8939246|reactome:R-HSA-8939247|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-8940973|reactome:R-HSA-8941284|reactome:R-HSA-8941326 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:CPjRPRBOYrP/Oj+k66XpWQysihY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q6P2C8-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722874 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q6p2c8-2(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:Q6P2C8-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:lDlawjPj7PITZ0nJSDAT8/gnG589606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P09497-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-10965328|ensembl:ENSP00000310812 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p09497-2(display_long)|uniprotkb:CLTB(gene name)|psi-mi:CLTB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 intact:EBI-726598(isoform-parent)|ensembl:ENSG00000175416(gene)|ensembl:ENST00000345807(transcript) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:r047u2aiXuVM26p1k2gGk3R5ucw9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9Y2X0-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-10970047|ensembl:ENSP00000379153 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9y2x0-2(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 intact:EBI-394541(isoform-parent)|ensembl:ENSG00000175221(gene)|ensembl:ENST00000395808(transcript)|uniprotkb:Q9Y2X0-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:FDFwyztYm5BxsnasSg/tAwUFeOY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:F8W943 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722859|ensembl:ENSP00000354710 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:f8w943_human(display_long)|uniprotkb:ASL(gene name)|psi-mi:ASL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000126522(gene)|ensembl:ENST00000362000(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0004056"(argininosuccinate lyase activity)|go:"GO:0042450"(arginine biosynthetic process via ornithine)|interpro:IPR000362(Fumarate lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR009049(Argininosuccinate lyase)|interpro:IPR020557|interpro:IPR022761|interpro:IPR024083|interpro:IPR029419 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:NuNuHl/OyBCpLHFo42MHDc4PKEY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9BUE0 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q8WXX5 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q93008-1 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-10964523|ensembl:ENSP00000367558 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q93008-1(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Short(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|intact:EBI-302524(isoform-parent)|uniprotkb:Q93008-1(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P20839-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722853|ensembl:ENSP00000420803 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p20839-2(display_long)|uniprotkb:IMPDH-I(gene name synonym)|uniprotkb:IMPDH1(gene name)|psi-mi:IMPDH1(display_short)|uniprotkb:IMPD1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:P20839-2(isoform-parent)|intact:EBI-2866691(isoform-parent)|ensembl:ENSG00000106348(gene)|ensembl:ENST00000496200(transcript) - - isoform-comment:No experimental confirmation available. figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:AO9F2LwyaAyiIMkvH8pprtwfMos9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q96G25 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:B7ZBT8 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722834|ensembl:ENSP00000386693 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:b7zbt8_human(display_long)|uniprotkb:PCDH15(gene name)|psi-mi:PCDH15(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000150275(gene)|ensembl:ENST00000409834(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0048839"(inner ear development)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR030718 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:P5OJIHD1o5mCVNCtwoI8Qw2Pkf49606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q53G59 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P60903 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-717048|uniprotkb:P08206|uniprotkb:Q5T1C5|uniprotkb:A8K4V8|ensembl:ENSP00000357799|ensembl:ENSP00000357801 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:s10aa_human(display_long)|uniprotkb:S100 calcium-binding protein A10(gene name synonym)|uniprotkb:Calpactin-1 light chain(gene name synonym)|uniprotkb:Calpactin I light chain(gene name synonym)|uniprotkb:p10 protein(gene name synonym)|uniprotkb:p11(gene name synonym)|uniprotkb:Cellular ligand of annexin II(gene name synonym)|uniprotkb:S100A10(gene name)|psi-mi:S100A10(display_short)|uniprotkb:ANX2LG(gene name synonym)|uniprotkb:CAL1L(gene name synonym)|uniprotkb:CLP11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_002957.1|ensembl:ENSG00000197747(gene)|ensembl:ENST00000368809(transcript)|ensembl:ENST00000368811(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005576"(extracellular region)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990665"(AnxA2-p11 complex)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028476|rcsb pdb:1A4P|rcsb pdb:1BT6|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRE|rcsb pdb:4HRG|rcsb pdb:4HRH|reactome:R-HSA-75205 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:WlxwW4qaHp6tcyEAYvQ2ut9SyRA9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9BQ67 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-351000|uniprotkb:Q8TF59|ensembl:ENSP00000253237|intact:EBI-9512815|uniprotkb:A0MNN5 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:grwd1_human(display_long)|uniprotkb:GRWD1(gene name)|psi-mi:GRWD1(display_short)|uniprotkb:GRWD(gene name synonym)|uniprotkb:WDR28(gene name synonym)|uniprotkb:KIAA1942(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 interpro:IPR022052|refseq:NP_113673.3|ensembl:ENSG00000105447(gene)|ensembl:ENST00000253237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|mint:Q9BQ67|interpro:IPR036322 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:rbkcKHsv+l3kFqh4SElBDft0b+A9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:F5H793 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722822|ensembl:ENSP00000442680 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:f5h793_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000111716(gene)|ensembl:ENST00000539782(transcript)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR036291 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:xxKQBT7kJ4YGikY2geFfrEz2pBc9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9P2N7-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722815|ensembl:ENSP00000440707 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9p2n7-2(display_long)|uniprotkb:KLHL13(gene name)|psi-mi:KLHL13(display_short)|uniprotkb:BKLHD2(gene name synonym)|uniprotkb:KIAA1309(gene name synonym)|uniprotkb:BTB and kelch domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000003096(gene)|ensembl:ENST00000545703(transcript)|uniprotkb:Q9P2N7-2(isoform-parent)|intact:EBI-1996321(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:2MRL3spWcfrnua6TB1wE19S6IHY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q08397 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-5395846|uniprotkb:Q6NUL3|uniprotkb:Q96BW7|ensembl:ENSP00000261921 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:loxl1_human(display_long)|uniprotkb:LOXL1(gene name)|psi-mi:LOXL1(display_short)|uniprotkb:LOXL(gene name synonym)|uniprotkb:Lysyl oxidase-like protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_005567.2|ensembl:ENSG00000129038(gene)|ensembl:ENST00000261921(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0018277"(protein deamination)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035904"(aorta development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR019828|reactome:R-HSA-1566948|reactome:R-HSA-2243919 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:JH05ghJNnvJeMUhA3j+L9jOqr3g9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q5JWT2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722806|ensembl:ENSP00000357037 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q5jwt2_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:Mediator of RNA polymerase II transcription subunit 23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000112282(gene)|ensembl:ENST00000368058(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR021629 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:H/D6RDJdrHK9Z70jzqDwt0BUzy49606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9P2I0 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1043224|uniprotkb:Q6NSJ1|uniprotkb:Q9H3W7|ensembl:ENSP00000298875|uniprotkb:B3KME1 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:cpsf2_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 100 kDa subunit(gene name synonym)|uniprotkb:CPSF2(gene name)|psi-mi:CPSF2(display_short)|uniprotkb:CPSF100(gene name synonym)|uniprotkb:KIAA1367(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR025069|interpro:IPR027075|interpro:IPR035639|interpro:IPR036866|mint:Q9P2I0|rcsb pdb:6URG|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|ensembl:ENSG00000165934(gene)|ensembl:ENST00000298875(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016020"(membrane)|refseq:NP_059133.1|refseq:NP_001309201.1|dip:DIP-42500N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:RYiaQ8q9VM7htGre4S8PkSQaCz89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q5QPE4 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722791|ensembl:ENSP00000406731 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q5qpe4_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000089006(gene)|ensembl:ENST00000419004(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:tH66/PNr9i8ys7P4MIjvIaQvdpA9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P14625 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q71F56 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394435|uniprotkb:A1L469|uniprotkb:Q68DN4|uniprotkb:Q9H8C0|uniprotkb:Q9NSY9|uniprotkb:Q9UFD8|uniprotkb:Q9UPX5|ensembl:ENSP00000281928 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:md13l_human(display_long)|uniprotkb:Mediator complex subunit 13-like(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 2(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component-like(gene name synonym)|uniprotkb:MED13L(gene name)|psi-mi:MED13L(display_short)|uniprotkb:KIAA1025(gene name synonym)|uniprotkb:PROSIT240(gene name synonym)|uniprotkb:THRAP2(gene name synonym)|uniprotkb:TRAP240L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_056150.1|ensembl:ENSG00000123066(gene)|ensembl:ENST00000281928(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009401(TRAP240)|interpro:IPR021643|interpro:IPR041285|mint:Q71F56|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Zdj5dM/HEWW8zS27yaXsR+ZOxZs9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9NPJ6 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9Y597 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-373299|uniprotkb:A0AV15|uniprotkb:Q49AG7|uniprotkb:Q504Q9|uniprotkb:Q6PJN6|uniprotkb:Q8ND58|uniprotkb:Q8NDJ0|uniprotkb:Q8WX16|uniprotkb:D3DTA6|ensembl:ENSP00000259154 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:kctd3_human(display_long)|uniprotkb:KCTD3(gene name)|psi-mi:KCTD3(display_short)|uniprotkb:Renal carcinoma antigen NY-REN-45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_057205.2|refseq:NP_001306223.1|refseq:NP_001306224.1|ensembl:ENST00000259154(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-HSA-9013148|ensembl:ENSG00000136636(gene) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:rd5uwUaxsHyv815HcLJmrI3sgNQ9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q15404-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722785 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q15404-2(display_long)|uniprotkb:RSU1(gene name)|psi-mi:RSU1(display_short)|uniprotkb:RSP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:Q15404-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:F14qZW5v3JSgIKWk+qx+9Po1GVc9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O00483 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:E9PRT1 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722774|ensembl:ENSP00000434174 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9prt1_human(display_long)|uniprotkb:KCTD21(gene name)|psi-mi:KCTD21(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000188997(gene)|ensembl:ENST00000525447(transcript)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:qhvs0QCpnXl2w13h+ofTt+H97C89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:G3V4A5 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722760|ensembl:ENSP00000451684 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:g3v4a5_human(display_long)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000133997(gene)|ensembl:ENST00000554963(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:0hq3Tp+czQsWU4HCUqIKQJHLoEI9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q92506 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-5461137|uniprotkb:A6NLX7|uniprotkb:Q5STP7|uniprotkb:Q9UIQ1|ensembl:ENSP00000230236|ensembl:ENSP00000363794|ensembl:ENSP00000387753|ensembl:ENSP00000403538|ensembl:ENSP00000406488|ensembl:ENSP00000413950 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:dhb8_human(display_long)|uniprotkb:Estradiol 17-beta-dehydrogenase 8(gene name synonym)|uniprotkb:HSD17B8(gene name)|psi-mi:HSD17B8(display_short)|uniprotkb:FABGL(gene name synonym)|uniprotkb:HKE6(gene name synonym)|uniprotkb:RING2(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 8(gene name synonym)|uniprotkb:3-oxoacyl-[acyl-carrier-protein] reductase(gene name synonym)|uniprotkb:Protein Ke6(gene name synonym)|uniprotkb:Testosterone 17-beta-dehydrogenase 8(gene name synonym)|uniprotkb:SDR30C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 30C member 1(gene name synonym)|uniprotkb:3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_055049.1|ensembl:ENSG00000112474(gene)|ensembl:ENSG00000204228(gene)|ensembl:ENSG00000225312(gene)|ensembl:ENSG00000228357(gene)|ensembl:ENSG00000228712(gene)|ensembl:ENSG00000232357(gene)|ensembl:ENST00000230236(transcript)|ensembl:ENST00000374662(transcript)|ensembl:ENST00000414463(transcript)|ensembl:ENST00000422433(transcript)|ensembl:ENST00000427295(transcript)|ensembl:ENST00000454191(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047025"("3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity")|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0048038"(quinone binding)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070404"(NADH binding)|go:"GO:1990204"(oxidoreductase complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|go:"GO:0006703"(estrogen biosynthetic process)|rcsb pdb:2PD6|rcsb pdb:4CQL|rcsb pdb:4CQM|reactome:R-HSA-75105 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:jXKOiIp3Eh3Q/IHoLpkWQY0fjhs9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P35222 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9BWW4-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722753 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9bww4-2(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:Q9BWW4-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:bi+RFQlOUWaeH5JpX+umlT3USEs9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O94952-1 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-11023203|ensembl:ENSP00000483508 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:o94952-1(display_long)|uniprotkb:FBXO21(gene name)|psi-mi:FBXO21(display_short)|uniprotkb:FBX21(gene name synonym)|uniprotkb:KIAA0875(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000135108(gene)|ensembl:ENST00000622495(transcript)|intact:EBI-311435(isoform-parent)|uniprotkb:O94952-1(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:8lf2JyYa6Oj2rpFwlCtXXo5CkY09606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q8WX93 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2803991|uniprotkb:Q9Y2J6|uniprotkb:Q9UQF5|uniprotkb:Q8N1M2|uniprotkb:Q7Z3W0|uniprotkb:Q86WE8|uniprotkb:B5MD56|uniprotkb:Q7L3E0|uniprotkb:Q9UGA0|uniprotkb:Q9Y3E9|uniprotkb:B7ZMM5|uniprotkb:B3KTG2 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:palld_human(display_long)|uniprotkb:KIAA0992(gene name synonym)|uniprotkb:SIH002(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-77(gene name synonym)|uniprotkb:CGI-151(orf name)|uniprotkb:PALLD(gene name)|psi-mi:PALLD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 interpro:IPR033017|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0060076"(excitatory synapse)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|rcsb pdb:2DM2|rcsb pdb:2DM3|go:"GO:0016477"(cell migration)|refseq:NP_001159580.1|refseq:NP_001159581.1|refseq:NP_001159582.1|refseq:NP_057165.3|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR036179|mint:Q8WX93 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:0GUVyoDYzf03b+bZXUa1n/fnP/Y9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P53618 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q8WTU2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722735|ensembl:ENSP00000275560|uniprotkb:Q2HIZ5|uniprotkb:Q6ZMG3|uniprotkb:Q96BF5 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:srb4d_human(display_long)|uniprotkb:Four scavenger receptor cysteine-rich domains-containing protein(gene name synonym)|uniprotkb:S4D-SRCRB(gene name synonym)|uniprotkb:SSC4D(gene name)|psi-mi:SSC4D(display_short)|uniprotkb:SRCRB4D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|ensembl:ENSG00000146700(gene)|ensembl:ENST00000275560(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|refseq:NP_542782.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:FnulMrTXfb92o1AC8HOEBWxDLxo9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q13643 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q8NDN9 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2811558|uniprotkb:Q969U9|intact:EBI-3044072|uniprotkb:Q8IY29|ensembl:ENSP00000258646|ensembl:ENSP00000367552 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rcbt1_human(display_long)|uniprotkb:RCBTB1(gene name)|psi-mi:RCBTB1(display_short)|uniprotkb:CLLD7(gene name synonym)|uniprotkb:E4.5(gene name synonym)|uniprotkb:Chronic lymphocytic leukemia deletion region gene 7 protein(gene name synonym)|uniprotkb:Regulator of chromosome condensation and BTB domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:XP_011533435.1|refseq:XP_011533436.1|refseq:NP_060661.3|ensembl:ENSG00000136144(gene)|ensembl:ENST00000258646(transcript)|ensembl:ENST00000378302(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)|refseq:XP_005266498.1 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:qlFRfKV0PffERWU2HnbL6M64qa09606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P17655 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1028956|uniprotkb:Q16738|uniprotkb:Q6PJT3|uniprotkb:Q8WU26|uniprotkb:Q9HBB1|uniprotkb:A6NDG7|ensembl:ENSP00000295006|uniprotkb:B7ZA96|uniprotkb:E7ES58 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:can2_human(display_long)|uniprotkb:CAPN2(gene name)|psi-mi:CAPN2(display_short)|uniprotkb:CANPL2(gene name synonym)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)|uniprotkb:Calpain large polypeptide L2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001139540.1|refseq:NP_001739.2|ensembl:ENSG00000162909(gene)|ensembl:ENST00000295006(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001824"(blastocyst development)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007565"(female pregnancy)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0005634"(nucleus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029539|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:P17655|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:2NQA|reactome:R-HSA-1474228|reactome:R-HSA-8862803|interpro:IPR002048(Calcium-binding EF-hand) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:r60XX66kihGVLaa9888soeXjc0M9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P35228-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722728 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p35228-2(display_long)|uniprotkb:NOS2(gene name)|psi-mi:NOS2(display_short)|uniprotkb:NOS2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:P35228-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:rKFr1Md01jNBgnv2ah/hJJUGU8o9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:B9A044 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722716|ensembl:ENSP00000386876 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:b9a044_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000135930(gene)|ensembl:ENST00000409495(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Jjxg2JKrPoD1qAzZQK/vFJjMGkc9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P04114 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q7L7V1-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722710 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q7l7v1-2(display_long)|uniprotkb:DHX32(gene name)|psi-mi:DHX32(display_short)|uniprotkb:DDX32(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 uniprotkb:Q7L7V1-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:AVtQO/x7ILeIKLThDUmyRkWXQzQ9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9UBF2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q9UKD2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1046493|ensembl:ENSP00000364320|uniprotkb:Q9BPV9|uniprotkb:Q5TG55|uniprotkb:Q96SS6|uniprotkb:B3KNB3 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:mrt4_human(display_long)|uniprotkb:MRTO4(gene name)|psi-mi:MRTO4(display_short)|uniprotkb:C1orf33(gene name synonym)|uniprotkb:MRT4(gene name synonym)|uniprotkb:Ribosome assembly factor MRTO4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000053372(gene)|ensembl:ENST00000330263(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:Q9UKD2|interpro:IPR033867|refseq:NP_057267.2 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:LpvX3By1Cp6MxlAx3d5qoDM3FNY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O43143 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:C9J1Z8 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722697|ensembl:ENSP00000412701 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:c9j1z8_human(display_long)|uniprotkb:ARF5(gene name)|psi-mi:ARF5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000004059(gene)|ensembl:ENST00000415666(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:QIfq2qacYf6er15jVoO65QoEGI89606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P40763 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N - - crc64:6C00632211C8012D figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q96HR3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q7KZF4 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q658Y4 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-3045545|ensembl:ENSP00000335082|uniprotkb:Q8TE89|uniprotkb:Q658T5|uniprotkb:B6YY23 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:f91a1_human(display_long)|uniprotkb:FAM91A1(gene name)|psi-mi:FAM91A1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000176853(gene)|ensembl:ENST00000334705(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0099041"(vesicle tethering to Golgi)|interpro:IPR028091|interpro:IPR028097|interpro:IPR039199|mint:Q658Y4|reactome:R-HSA-9013407|refseq:NP_001304846.1|refseq:NP_001304847.1|refseq:NP_659400.2 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:0Fq4tmA02p3P6sxVWlt0RA24hrc9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:C9JLU1 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-11076042|ensembl:ENSP00000409065 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:c9jlu1_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000163882(gene)|ensembl:ENST00000455712(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006351"(transcription, DNA-templated)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:cWioC0bRrUHFlH3rBu2AwgRiKiY9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P60891 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-749195|uniprotkb:P09329|uniprotkb:B2R6T7|uniprotkb:B1ALA8|uniprotkb:B4DNL6|uniprotkb:D3DUX6|ensembl:ENSP00000361512 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:prps1_human(display_long)|uniprotkb:Phosphoribosyl pyrophosphate synthase I(gene name synonym)|uniprotkb:PRPS1(gene name)|psi-mi:PRPS1(display_short)|uniprotkb:PPRibP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_001191331.1|refseq:NP_002755.1|ensembl:ENSG00000147224(gene)|ensembl:ENST00000372435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006221"(pyrimidine nucleotide biosynthetic process)|go:"GO:0007399"(nervous system development)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046101"(hypoxanthine biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|go:"GO:0006144"(purine nucleobase metabolic process)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|rcsb pdb:2H06|rcsb pdb:2H07|rcsb pdb:2H08|rcsb pdb:2HCR|rcsb pdb:3EFH|rcsb pdb:3S5J|rcsb pdb:4F8E|rcsb pdb:4LYG|rcsb pdb:4LZN|rcsb pdb:4LZO|rcsb pdb:4M0P|rcsb pdb:4M0U|reactome:R-HSA-73843|dip:DIP-61999N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:+Hih2M7JLTsjEglauBlPj182h9M9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P61981 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:K7EM73 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723328|ensembl:ENSP00000466386 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:k7em73_human(display_long)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calpain small subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000126247(gene)|ensembl:ENST00000591041(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR029642 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:+2N4TD0DfNn8TzEtTcEBD1cY1b49606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:I3L2C7 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-11066860|ensembl:ENSP00000459565 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:i3l2c7_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:XP_005256727.1|refseq:XP_011522214.1|refseq:XP_011522215.1|ensembl:ENSG00000179409(gene)|ensembl:ENST00000576778(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|interpro:IPR033265 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:OkovwUEjpcuicbkuypcYP0bjw0Y9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:O15514 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q96AY3 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-2372475|uniprotkb:Q7Z3R4|uniprotkb:Q9H3N3|uniprotkb:Q9H6N5|uniprotkb:Q9UF89|uniprotkb:Q9H6J3|ensembl:ENSP00000317232 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:fkb10_human(display_long)|uniprotkb:FKBP10(gene name)|psi-mi:FKBP10(display_short)|uniprotkb:FKBP65(gene name synonym)|uniprotkb:FK506-binding protein 10(gene name synonym)|uniprotkb:Immunophilin FKBP65(gene name synonym)|uniprotkb:65 kDa FK506-binding protein(gene name synonym)|uniprotkb:PSEC0056(orf name)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 refseq:NP_068758.3|ensembl:ENSG00000141756(gene)|ensembl:ENST00000321562(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0018208"(peptidyl-proline modification)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0042060"(wound healing)|go:"GO:0085029"(extracellular matrix assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q96AY3 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:+oJpWT3zBh/fq0DqKPapFoVt3u09606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q709C8-4 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20722686|ensembl:ENSP00000379235 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q709c8-4(display_long)|uniprotkb:VPS13C(gene name)|psi-mi:VPS13C(display_short)|uniprotkb:KIAA1421(gene name synonym)|uniprotkb:1B(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000129003(gene)|ensembl:ENST00000395898(transcript)|intact:EBI-2819265(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:V08DrMDYjIr0aNPGpkQVjvHJj/Q9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:Q4VXZ8 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723316|ensembl:ENSP00000400374|ensembl:ENSP00000487756 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q4vxz8_human(display_long)|uniprotkb:DECR2(gene name)|psi-mi:DECR2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000242612(gene)|ensembl:ENSG00000274296(gene)|ensembl:ENST00000424398(transcript)|ensembl:ENST00000633596(transcript)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:bcOMmBUNR89ZKeIpftk1/m1P8WI9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:B0YIW6 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723300|ensembl:ENSP00000352385 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:b0yiw6_human(display_long)|uniprotkb:ARCN1(gene name)|psi-mi:ARCN1(display_short)|uniprotkb:hCG_40220(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000095139(gene)|ensembl:ENST00000359415(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:Pgd3aKxQeQrYHWRu+npxBsig86s9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:C9JJ54 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-20723288|ensembl:ENSP00000395416 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:c9jj54_human(display_long)|uniprotkb:WDFY1(gene name)|psi-mi:WDFY1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 ensembl:ENSG00000085449(gene)|ensembl:ENST00000429915(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR042234 - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:9avEUAvEAv2TEJhYmME6mPSO3Fg9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6 uniprotkb:P49336-2 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 intact:EBI-11039720 psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p49336-2(display_long)|uniprotkb:CDK8(gene name)|psi-mi:CDK8(display_short)|uniprotkb:Cell division protein kinase 8(gene name synonym)|uniprotkb:Mediator complex subunit CDK8(gene name synonym)|uniprotkb:Mediator of RNA polymerase II transcription subunit CDK8(gene name synonym)|uniprotkb:Protein kinase K35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723339|imex:IM-26492-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 intact:EBI-394377(isoform-parent)|uniprotkb:P49336-2(isoform-parent) - - - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs F8W9R9, F5H4E4, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2021/04/12 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:QfOhtWEkdFrlqfZVYGzRjuANdqM9606 rigid:athm2qURU2oA+WVNSLDgU4Ds5so false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 intact:EBI-8011851 intact:EBI-20723514|ensembl:ENSP00000410707 intact:MINT-8395041 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:f5gyc1_human(display_short)|psi-mi:EBI-8011851(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) uniprotkb:F5GYC1(uniprot-removed-ac) - - comment:mint|comment:homomint|no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:TMMmEXqhZmllyr2F+jqBoFxe56A9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q96EE3 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-922818|uniprotkb:Q8NFU6|uniprotkb:Q96MH3|uniprotkb:Q9C069|uniprotkb:A8K5B1|ensembl:ENSP00000262124 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:seh1_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit SEH1(gene name synonym)|uniprotkb:SEH1L(gene name)|psi-mi:SEH1L(display_short)|uniprotkb:SEC13L(gene name synonym)|uniprotkb:SEH1(gene name synonym)|uniprotkb:SEC13-like protein(gene name synonym)|uniprotkb:GATOR complex protein SEH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_001013455.1|refseq:NP_112493.2|ensembl:ENSP00000262124|ensembl:ENST00000399892|ensembl:ENSP00000382779|ensembl:ENSG00000085415(gene)|ensembl:ENST00000262124(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034629"|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0061700"(GATOR2 complex)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037363|interpro:IPR037597|mint:Q96EE3|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:I/aUTa3zTawK6QwtkrUkO8B51W49606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:O95782-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-10965313|ensembl:ENSP00000346246 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:o95782-2(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) intact:EBI-353552(isoform-parent)|ensembl:ENSG00000196961(gene)|ensembl:ENST00000354293(transcript)|uniprotkb:O95782-2(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:TqGX2+cKSxTF8iah3B57Fg54+949606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P98170 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q6AZZ1 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-2130449|uniprotkb:A6NI19|uniprotkb:A8K551|uniprotkb:Q8WZ70|uniprotkb:Q96PF7|uniprotkb:Q9H9C2|uniprotkb:Q9NW18|uniprotkb:B3KPM5|uniprotkb:Q96LE5|uniprotkb:B4DVK4|ensembl:ENSP00000300747 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:tri68_human(display_long)|uniprotkb:TRIM68(gene name)|psi-mi:TRIM68(display_short)|uniprotkb:RNF137(gene name synonym)|uniprotkb:SS56(gene name synonym)|uniprotkb:RING finger protein 137(gene name synonym)|uniprotkb:SSA protein SS-56(gene name synonym)|uniprotkb:GC109(gene name synonym)|uniprotkb:Tripartite motif-containing protein 68(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_001291425.1|refseq:NP_060543.5|ensembl:ENSG00000167333(gene)|ensembl:ENST00000300747(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042656|interpro:IPR043136|reactome:R-HSA-877300 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:hm0MRstol6cN4p4oG4p2iuQhSEo9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P55735 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P22234 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q10570 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q08209-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-11959013|ensembl:ENSP00000378322 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:q08209-2(display_long)|uniprotkb:PPP3CA(gene name)|psi-mi:PPP3CA(display_short)|uniprotkb:CALNA(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:CNA(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000138814(gene)|ensembl:ENST00000394853(transcript)|intact:EBI-352922(isoform-parent)|uniprotkb:Q08209-2(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:lP58KeK5q9YvkzOMzav8dd92K4Q9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:C9JJ54 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723288|ensembl:ENSP00000395416 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:c9jj54_human(display_long)|uniprotkb:WDFY1(gene name)|psi-mi:WDFY1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000085449(gene)|ensembl:ENST00000429915(transcript)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR042234 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:9avEUAvEAv2TEJhYmME6mPSO3Fg9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q9BWW4-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20722753 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:q9bww4-2(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) uniprotkb:Q9BWW4-2(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:bi+RFQlOUWaeH5JpX+umlT3USEs9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q9UNQ2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-395738|uniprotkb:O76025|uniprotkb:Q9BU77|uniprotkb:Q9UES1|ensembl:ENSP00000199320 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:dim1_human(display_long)|uniprotkb:DIMT1L(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1 homolog(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1-like(gene name synonym)|uniprotkb:HUSSY-05(orf name)|uniprotkb:"Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase"(gene name synonym)|uniprotkb:Probable 18S rRNA dimethylase(gene name synonym)|uniprotkb:DIMT1(gene name)|psi-mi:DIMT1(display_short)|uniprotkb:"Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_055288.1|ensembl:ENSG00000086189(gene)|ensembl:ENST00000199320(transcript)|go:"GO:0000179"("rRNA (adenine-N6,N6-)-dimethyltransferase activity")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0031167"(rRNA methylation)|go:"GO:0052909"("18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR011530(rRNA adenine dimethylase)|interpro:IPR020596|interpro:IPR020598|interpro:IPR029063|mint:Q9UNQ2|rcsb pdb:1ZQ9|rcsb pdb:6W6C|rcsb pdb:6W6F|reactome:R-HSA-6790901|refseq:NP_001335005.1 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:hx0FRrx+XTeoziOqfesiw4KL+wo9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:F5H793 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20722822|ensembl:ENSP00000442680 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:f5h793_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000111716(gene)|ensembl:ENST00000539782(transcript)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR036291 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:xxKQBT7kJ4YGikY2geFfrEz2pBc9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q12824-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-358436|ensembl:ENSP00000383984|ensembl:ENSP00000486870 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:q12824-2(display_long)|uniprotkb:INI1B(isoform synonym)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000407422(transcript)|ensembl:ENST00000631333(transcript)|intact:EBI-358419(snf5_human)|uniprotkb:Q12824-2(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:nCACo1KHiMlwp3pROvLzVFOl5pE9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P46940 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q86U70-3 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723506 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:q86u70-3(display_long)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:Nuclear LIM interactor(gene name synonym)|uniprotkb:b(isoform synonym)|uniprotkb:LDB1(gene name)|psi-mi:LDB1(display_short)|uniprotkb:CLIM2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) intact:EBI-677177(isoform-parent) - - isoform-comment:Due to intron retention. Lacks LIM-binding domain. figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:CAVFxLyex6ozWp90rDJKqX4eOZs9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:C9J2Q4 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723609|ensembl:ENSP00000397195 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:c9j2q4_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000168385(gene)|ensembl:ENST00000428282(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0030496"(midbody)|go:"GO:0031514"(motile cilium)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051301"(cell division)|go:"GO:0060170"(ciliary membrane)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:+Yve/3l8olpItIhNLpuWq+g/tAU9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q13085-4 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-12562760|ensembl:ENSP00000478577|ensembl:ENSP00000483300 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:q13085-4(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000616317(transcript)|ensembl:ENST00000619487(transcript)|uniprotkb:Q13085-4(isoform-parent)|intact:EBI-717681(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:pLStO7poopKGvMufughT4SUnJHQ9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q9NPJ6 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q15024 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:E9PPM8 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723594|ensembl:ENSP00000436999 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:e9ppm8_human(display_long)|uniprotkb:DERA(gene name)|psi-mi:DERA(display_short)|uniprotkb:Phosphodeoxyriboaldolase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENST00000532964(transcript)|go:"GO:0004139"(deoxyribose-phosphate aldolase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0046386"(deoxyribose phosphate catabolic process)|interpro:IPR002915(Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase)|interpro:IPR011343(Deoxyribose-phosphate aldolase)|interpro:IPR013785(Aldolase-type TIM barrel)|ensembl:ENSG00000023697(gene)|refseq:NP_001287708.1 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:oTL6YDxsIptKPUPRxa06JYZlcZE9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q16831 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-2850872|uniprotkb:Q15362|uniprotkb:D3DVM4|ensembl:ENSP00000330032|ensembl:ENSP00000378931 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:upp1_human(display_long)|uniprotkb:UP(gene name synonym)|uniprotkb:UPP1(gene name)|psi-mi:UPP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:XP_011513814.1|refseq:NP_003355.1|refseq:NP_001274355.1|refseq:NP_001274357.1|refseq:NP_001274358.1|refseq:NP_001274359.1|ensembl:ENSG00000183696(gene)|ensembl:ENST00000331803(transcript)|ensembl:ENST00000395564(transcript)|go:"GO:0004850"(uridine phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006218"(uridine catabolic process)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0009032"(thymidine phosphorylase activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044206"(UMP salvage)|go:"GO:0046050"(UMP catabolic process)|go:"GO:0046074"(dTMP catabolic process)|go:"GO:0046079"(dUMP catabolic process)|go:"GO:0047847"(deoxyuridine phosphorylase activity)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010059(Uridine phosphorylase, eukaryotic)|interpro:IPR018016|interpro:IPR035994|rcsb pdb:3EUE|rcsb pdb:3EUF|rcsb pdb:3NBQ|reactome:R-HSA-73614|reactome:R-HSA-73621 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:B1cM7wNyPh/lNm7Ixtf4q4vilow9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q96JB6 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-749562|uniprotkb:Q96DY1|uniprotkb:Q96PC0|uniprotkb:Q9H6T5|uniprotkb:Q5W0B3|ensembl:ENSP00000260702 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:loxl4_human(display_long)|uniprotkb:Lysyl oxidase-like protein 4(gene name synonym)|uniprotkb:Lysyl oxidase-related protein C(gene name synonym)|uniprotkb:LOXL4(gene name)|psi-mi:LOXL4(display_short)|uniprotkb:LOXC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_115587.6|ensembl:ENSG00000138131(gene)|ensembl:ENST00000260702(transcript)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0016020"(membrane)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR019828|interpro:IPR036772|mint:Q96JB6|reactome:R-HSA-1566948|reactome:R-HSA-2243919 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:yOUffU5WqmaUNvrXvX1ie0RWEG49606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P53396-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-16399011|ensembl:ENSP00000345398|ensembl:ENSP00000377474 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:p53396-2(display_long)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000131473(gene)|ensembl:ENST00000353196(transcript)|ensembl:ENST00000393896(transcript)|intact:EBI-1042794(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:pBJJcwGUAn6Tyx0dgKPXQtcoLFE9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P42224 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:O95429-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723588 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:o95429-2(display_long)|uniprotkb:BAG4(gene name)|psi-mi:BAG4(display_short)|uniprotkb:SODD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) uniprotkb:O95429-2(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:ctqGZupeEdCgW37LVrgOqHMxhkw9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q9UMS4 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-395746|ensembl:ENSP00000227524 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:prp19_human(display_long)|uniprotkb:PRPF19(gene name)|psi-mi:PRPF19(display_short)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:NMP200(gene name synonym)|uniprotkb:PRP19(gene name synonym)|uniprotkb:SNEV(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000110107(gene)|ensembl:ENST00000227524(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|refseq:NP_055317.1|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q9UMS4|rcsb pdb:4LG8|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|dip:DIP-32978N - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:5TseaFcCOVVWjJeMF/H7k29nd3c9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:B0QYD3 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723574|ensembl:ENSP00000385060 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:b0qyd3_human(display_long)|uniprotkb:APOBEC3B(gene name)|psi-mi:APOBEC3B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000179750(gene)|ensembl:ENST00000402182(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:jzAgfcX1UoyQY938zmVPcGHnpDo9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:E9PIR7 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723555|ensembl:ENSP00000433935 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:e9pir7_human(display_long)|uniprotkb:TXNRD1(gene name)|psi-mi:TXNRD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000198431(gene)|ensembl:ENST00000527688(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:W7Kn+mfDVYACMOU1dz/qITv6BQk9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q9NPL8 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-6268651|ensembl:ENSP00000418803|uniprotkb:D3DN81|uniprotkb:Q6IAJ7|uniprotkb:Q6UWU6|uniprotkb:Q9NPR3|uniprotkb:Q9NPS5|uniprotkb:Q9P0Y6 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:tidc1_human(display_long)|uniprotkb:Translocase of inner mitochondrial membrane domain-containing protein 1(gene name synonym)|uniprotkb:UNQ247/PRO284(orf name)|uniprotkb:TIMMDC1(gene name)|psi-mi:TIMMDC1(display_short)|uniprotkb:C3orf1(gene name synonym)|uniprotkb:Protein M5-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000113845(gene)|ensembl:ENST00000494664(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-6799198|refseq:NP_057673.2 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:unRvwLcwr8HPurvP0QImnk9d5ko9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q9Y5B8-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-16813363 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:q9y5b82(display_long)|uniprotkb:NME7(gene name)|psi-mi:NME7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) uniprotkb:Q9Y5B8-2(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:+5rLvYG60Lnrw1a2LRI8sgmIRuI9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:O94952-1 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-11023203|ensembl:ENSP00000483508 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:o94952-1(display_long)|uniprotkb:FBXO21(gene name)|psi-mi:FBXO21(display_short)|uniprotkb:FBX21(gene name synonym)|uniprotkb:KIAA0875(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000135108(gene)|ensembl:ENST00000622495(transcript)|intact:EBI-311435(isoform-parent)|uniprotkb:O94952-1(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:8lf2JyYa6Oj2rpFwlCtXXo5CkY09606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P23142-3 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20722901|ensembl:ENSP00000393812 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:p23142-3(display_long)|uniprotkb:FBLN1(gene name)|psi-mi:FBLN1(display_short)|uniprotkb:PP213(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000077942(gene)|ensembl:ENST00000442170(transcript)|uniprotkb:P23142-3(isoform-parent)|intact:EBI-726652(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:LlNjk4lysFMyAtlGZJ3zW2tmXs89606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q15758 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q13555-9 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723546 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:q13555-9(display_long)|uniprotkb:CAMK2G(gene name)|psi-mi:CAMK2G(display_short)|uniprotkb:CAMK(gene name synonym)|uniprotkb:CAMK-II(gene name synonym)|uniprotkb:CAMKG(gene name synonym)|uniprotkb:gamma D(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) uniprotkb:Q13555-9(isoform-parent)|intact:EBI-1383465(isoform-parent) - - isoform-comment:Contains a phosphoserine at position 325. Contains a phosphoserine at position 338. figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:ZFdpGAi+HWifP/5jsUYAK5dYQck9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:B7Z1N3 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723539 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:b7z1n3_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|refseq:XP_005260489.1|interpro:IPR007245(Gpi16 subunit, GPI transamidase component) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:Ly2oXTwQrFyKc2oTMey6qMSUksc9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q8N5L8 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-10189722|uniprotkb:D3DRM5|ensembl:ENSP00000297613|ensembl:ENSP00000368242 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:rp25l_human(display_long)|uniprotkb:RPP25L(gene name)|psi-mi:RPP25L(display_short)|uniprotkb:C9orf23(gene name synonym)|uniprotkb:Rpp25-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_680544.1|refseq:NP_680545.1|ensembl:ENSG00000164967(gene)|ensembl:ENST00000297613(transcript)|ensembl:ENST00000378959(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR002775(Alba, DNA/RNA-binding protein)|interpro:IPR036882 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:WpTe4D9lvRLa+96z7U42c722f2A9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:O75643 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-1045395|uniprotkb:O94884|uniprotkb:Q6PX59|uniprotkb:Q8NBE6|uniprotkb:Q96IF2|uniprotkb:Q9H7S0|uniprotkb:Q6NZY0|intact:EBI-1051631|ensembl:ENSP00000317123 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:u520_human(display_long)|uniprotkb:SNRNP200(gene name)|psi-mi:SNRNP200(display_short)|uniprotkb:HELIC2(gene name synonym)|uniprotkb:KIAA0788(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)|uniprotkb:Activating signal cointegrator 1 complex subunit 3-like 1(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:ASCC3L1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_054733.2|ensembl:ENSG00000144028(gene)|ensembl:ENST00000323853(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:O75643|rcsb pdb:2Q0Z|rcsb pdb:3JCR|rcsb pdb:4F91|rcsb pdb:4F92|rcsb pdb:4F93|rcsb pdb:4KIT|rcsb pdb:5O9Z|rcsb pdb:5URJ|rcsb pdb:5URK|rcsb pdb:5URM|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6S8O|rcsb pdb:6S8Q|rcsb pdb:6S9I|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7BDI|rcsb pdb:7BDJ|rcsb pdb:7BDK|rcsb pdb:7BDL|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:XP_016859092.1|dip:DIP-31659N - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:2ZAcbMfMlk2xWWAiy7MeCL0CHtM9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P13807-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723533 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:p13807-2(display_long)|uniprotkb:GYS1(gene name)|psi-mi:GYS1(display_short)|uniprotkb:GYS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) uniprotkb:P13807-2(isoform-parent) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:vMdh+bA5juIzeq90ydIKVgBSyk89606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P35222 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q8TDB6 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-2340392|uniprotkb:Q5MJP7|uniprotkb:Q53ZZ3|uniprotkb:B3KWH6|ensembl:ENSP00000296161 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:dtx3l_human(display_long)|uniprotkb:DTX3L(gene name)|psi-mi:DTX3L(display_short)|uniprotkb:BBAP(gene name synonym)|uniprotkb:B-lymphoma- and BAL-associated protein(gene name synonym)|uniprotkb:Rhysin-2(gene name synonym)|uniprotkb:Protein deltex-3-like(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase DTX3L(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_612144.1|ensembl:ENSG00000163840(gene)|ensembl:ENST00000296161(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0015031"(protein transport)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:2000646"(positive regulation of receptor catabolic process)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399|interpro:IPR042843|rcsb pdb:3PG6|reactome:R-HSA-983168 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:d2ctDfd7pj1wRA3HxmyWJ5nL19Y9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q96SW2-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-10693561|ensembl:ENSP00000412499 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:q96sw2-2(display_long)|uniprotkb:CRBN(gene name)|psi-mi:CRBN(display_short)|uniprotkb:AD-006(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000113851(gene)|ensembl:ENST00000432408(transcript)|intact:EBI-2510250(isoform-parent)|uniprotkb:Q96SW2-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:gWwrgG/aX24CQNiDPMV0dxKsmNE9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:E9PKP7 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20723521|ensembl:ENSP00000431539 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:e9pkp7_human(display_long)|uniprotkb:UBTF(gene name)|psi-mi:UBTF(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) ensembl:ENSG00000108312(gene)|ensembl:ENST00000527034(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR029215|interpro:IPR036910 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:GsWgBZrgxYBl8gRAXQFKSh9pwaQ9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q8WTU2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-20722735|ensembl:ENSP00000275560|uniprotkb:Q2HIZ5|uniprotkb:Q6ZMG3|uniprotkb:Q96BF5 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:srb4d_human(display_long)|uniprotkb:Four scavenger receptor cysteine-rich domains-containing protein(gene name synonym)|uniprotkb:S4D-SRCRB(gene name synonym)|uniprotkb:SSC4D(gene name)|psi-mi:SSC4D(display_short)|uniprotkb:SRCRB4D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|ensembl:ENSG00000146700(gene)|ensembl:ENST00000275560(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|refseq:NP_542782.1 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:FnulMrTXfb92o1AC8HOEBWxDLxo9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q8WXX5 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q08397 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-5395846|uniprotkb:Q6NUL3|uniprotkb:Q96BW7|ensembl:ENSP00000261921 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:loxl1_human(display_long)|uniprotkb:LOXL1(gene name)|psi-mi:LOXL1(display_short)|uniprotkb:LOXL(gene name synonym)|uniprotkb:Lysyl oxidase-like protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_005567.2|ensembl:ENSG00000129038(gene)|ensembl:ENST00000261921(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0018277"(protein deamination)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035904"(aorta development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR019828|reactome:R-HSA-1566948|reactome:R-HSA-2243919 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:JH05ghJNnvJeMUhA3j+L9jOqr3g9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q9NR30-2 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-6654714|ensembl:ENSP00000480334 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:q9nr30-2(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:DEAD box protein 21(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) intact:EBI-357942(isoform-parent)|ensembl:ENSG00000165732(gene)|ensembl:ENST00000620315(transcript)|uniprotkb:Q9NR30-2(isoform-parent) - - isoform-comment:Contains a N-acetylmethionine at position 1. figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:G4lZy34GneSNYW02rbAZ+Yhm9j09606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:P22830 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-1390356|uniprotkb:Q8IXN1|uniprotkb:Q8NAN0|uniprotkb:A8KA72|ensembl:ENSP00000262093 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:hemh_human(display_long)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)|uniprotkb:FECH(gene name)|psi-mi:FECH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_000131.2|refseq:NP_001012533.1|dip:DIP-39632N|ensembl:ENSG00000066926(gene)|ensembl:ENST00000262093(transcript)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010288"(response to lead ion)|go:"GO:0017085"(response to insecticide)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0046501"(protoporphyrinogen IX metabolic process)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051597"(response to methylmercury)|go:"GO:0070541"(response to platinum ion)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|interpro:IPR033644|interpro:IPR033659|rcsb pdb:1HRK|rcsb pdb:2HRC|rcsb pdb:2HRE|rcsb pdb:2PNJ|rcsb pdb:2PO5|rcsb pdb:2PO7|rcsb pdb:2QD1|rcsb pdb:2QD2|rcsb pdb:2QD3|rcsb pdb:2QD4|rcsb pdb:2QD5|rcsb pdb:3AQI|rcsb pdb:3HCN|rcsb pdb:3HCO|rcsb pdb:3HCP|rcsb pdb:3HCR|rcsb pdb:3W1W|rcsb pdb:4F4D|rcsb pdb:4KLA|rcsb pdb:4KLC|rcsb pdb:4KLR|rcsb pdb:4KMM|rcsb pdb:4MK4|reactome:R-HSA-189451 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:Rh4ulxUAnCedNUVAABAhY4iOnuo9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q5JTZ9 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-308736|uniprotkb:Q8N198|uniprotkb:Q96D02|uniprotkb:Q9ULF0|uniprotkb:A2RRN5|ensembl:ENSP00000244571 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:syam_human(display_long)|uniprotkb:KIAA1270(gene name synonym)|uniprotkb:AARS2(gene name)|psi-mi:AARS2(display_short)|uniprotkb:AARSL(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_065796.1|ensembl:ENSG00000124608(gene)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:Q5JTZ9|rcsb pdb:6NLQ|rcsb pdb:6NLY|rcsb pdb:6NOW|reactome:R-HSA-379726|ensembl:ENST00000244571(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006400"(tRNA modification)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0070143"(mitochondrial alanyl-tRNA aminoacylation)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc) - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:RzNZMsaNjWpD4eB5AdgpjhC3vP09606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q09666 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-2 uniprotkb:Q9NZN3 intact:EBI-20723514|ensembl:ENSP00000410707 intact:EBI-2870749|uniprotkb:Q9NZB3|uniprotkb:Q8N514|uniprotkb:B4DFR5|uniprotkb:D6W574|ensembl:ENSP00000327116 psi-mi:q96rs6-2(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-S(isoform synonym) psi-mi:ehd3_human(display_long)|uniprotkb:EHD3(gene name)|psi-mi:EHD3(display_short)|uniprotkb:EHD2(gene name synonym)|uniprotkb:PAST3(gene name synonym)|uniprotkb:PAST homolog 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723623|imex:IM-26492-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000427660(transcript)|intact:EBI-2512429(isoform-parent)|uniprotkb:Q96RS6-2(isoform-parent) refseq:NP_055415.1|ensembl:ENSG00000013016(gene)|ensembl:ENST00000322054(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9NZN3|reactome:R-HSA-983231 - - - figure legend:f3 st1|comment:the protein corresponding to the uniprot ID F8W9R9 provided by authors in supplementary table 1, was not included because it has been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/09/21 rogid:CBlXuU5lx3+8KwhP/feJAebzu709606 rogid:nyg47ipzaBxbLMl9jSWet1FffNw9606 rigid:VXh0bKSO4QW4Sj481nkXhAp1ufo false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9BZQ6 intact:EBI-20723690 intact:EBI-2556756|uniprotkb:B7ZLZ2|uniprotkb:Q9UFV7|uniprotkb:Q0VGM5|uniprotkb:B2RCH6|uniprotkb:Q9HCW1|uniprotkb:Q5TEZ0|uniprotkb:Q7L2Y5|ensembl:ENSP00000318147|intact:EBI-11137062 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:edem3_human(display_long)|uniprotkb:C1orf22(gene name synonym)|uniprotkb:EDEM3(gene name)|psi-mi:EDEM3(display_short)|uniprotkb:Alpha-1,2-mannosidase EDEM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_079467.3|ensembl:ENSG00000116406(gene)|ensembl:ENST00000318130(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR003137(Protease-associated PA)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR037322|interpro:IPR044674|reactome:R-HSA-901032|refseq:NP_001306889.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:Y+n8Hhal53ri5I8jlKzXI6S8pk09606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9BWG4 intact:EBI-20723690 intact:EBI-744719|ensembl:ENSP00000270061|uniprotkb:Q9BWW5 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:ssbp4_human(display_long)|uniprotkb:SSBP4(gene name)|psi-mi:SSBP4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000130511(gene)|ensembl:ENST00000270061(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWG4|refseq:NP_001009998.1|refseq:NP_116016.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:c0T7Xjz4MbjSZpCzJlpGVFbFYy89606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q4VXZ8 intact:EBI-20723690 intact:EBI-20723316|ensembl:ENSP00000400374|ensembl:ENSP00000487756 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q4vxz8_human(display_long)|uniprotkb:DECR2(gene name)|psi-mi:DECR2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000242612(gene)|ensembl:ENSG00000274296(gene)|ensembl:ENST00000424398(transcript)|ensembl:ENST00000633596(transcript)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:bcOMmBUNR89ZKeIpftk1/m1P8WI9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q53G59 intact:EBI-20723690 intact:EBI-740929|ensembl:ENSP00000356230|uniprotkb:A6NEN8|uniprotkb:B7Z7B8|uniprotkb:Q9HBX5 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:klh12_human(display_long)|uniprotkb:CUL3-interacting protein 1(gene name synonym)|uniprotkb:KLHL12(gene name)|psi-mi:KLHL12(display_short)|uniprotkb:C3IP1(gene name synonym)|uniprotkb:DKIR homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|mint:Q53G59|rcsb pdb:2VPJ|rcsb pdb:6TTK|rcsb pdb:6V7O|reactome:R-HSA-4641258|refseq:NP_067646.1|ensembl:ENSG00000117153(gene)|ensembl:ENST00000367261(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0034451"(centriolar satellite)|refseq:NP_001289980.1|refseq:NP_001290038.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:C4I/Ys9vqNqfG61HsXRZhywP4vE9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q2TAY7 intact:EBI-20723690 intact:EBI-298027|uniprotkb:Q9BU59|uniprotkb:Q9HA96|uniprotkb:Q9NVD1|ensembl:ENSP00000380336|uniprotkb:B4E3L0 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:smu1_human(display_long)|uniprotkb:Smu-1 suppressor of mec-8 and unc-52 protein homolog(gene name synonym)|uniprotkb:SMU1(gene name)|psi-mi:SMU1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENST00000397149(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q2TAY7|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6Q8F|rcsb pdb:6Q8I|rcsb pdb:6Q8J|ensembl:ENSG00000122692(gene)|refseq:NP_060695.2 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:zbTRfKynNIUSFY8IEqyYWh3JSho9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:E9PGM9 intact:EBI-20723690 intact:EBI-20723841|ensembl:ENSP00000396466 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pgm9_human(display_long)|uniprotkb:RBM6(gene name)|psi-mi:RBM6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000004534(gene)|ensembl:ENST00000443081(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR028806|interpro:IPR034123|interpro:IPR034125|interpro:IPR035617|interpro:IPR035979|interpro:IPR041591|refseq:XP_005264841.1|refseq:XP_006712979.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:RjuKWDX49ExkT1xVoWXQWzEKNyw9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q8IZH2-2 intact:EBI-20723690 intact:EBI-10965083|ensembl:ENSP00000376707 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q8izh2-2(display_long)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000114127(gene)|ensembl:ENST00000392981(transcript)|intact:EBI-372406(isoform-parent)|uniprotkb:Q8IZH2-2(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:E7g0flI0E0BQBTcMcbjByo6F/eQ9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:O60244 intact:EBI-20723690 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:E7ET89 intact:EBI-20723690 intact:EBI-20723825|ensembl:ENSP00000397648 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e7et89_human(display_long)|uniprotkb:DTX2(gene name)|psi-mi:DTX2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000091073(gene)|ensembl:ENST00000446600(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004170(WWE)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018123|interpro:IPR018957|interpro:IPR037197|interpro:IPR039396|interpro:IPR039398|interpro:IPR039399 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:Hi7mWEIMbM7Ns9/wFLBz42K5xRg9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9UHV7 intact:EBI-20723690 intact:EBI-394440|uniprotkb:O60334|uniprotkb:B2RU05|ensembl:ENSP00000380888 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med13_human(display_long)|uniprotkb:TRAP240(gene name synonym)|uniprotkb:MED13(gene name)|psi-mi:MED13(display_short)|uniprotkb:ARC250(gene name synonym)|uniprotkb:KIAA0593(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex component DRIP250(gene name synonym)|uniprotkb:Activator-recruited cofactor 250 kDa component(gene name synonym)|uniprotkb:THRAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_005112.2|ensembl:ENSG00000108510(gene)|ensembl:ENST00000397786(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR009401(TRAP240)|interpro:IPR041285|mint:Q9UHV7|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31468N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:ZNWwmsetsKLA56joRzRL0UKjq9Y9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q3ZCM7 intact:EBI-20723690 intact:EBI-302558|ensembl:ENSP00000456206|intact:EBI-1390656|uniprotkb:Q5SQX9|uniprotkb:Q8WZ78 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:tbb8_human(display_long)|uniprotkb:TUBB8(gene name)|psi-mi:TUBB8(display_short)|uniprotkb:Tubulin beta 8 class VIII(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9619483|ensembl:ENSG00000261456(gene)|ensembl:ENST00000568584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072687"(meiotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3ZCM7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|refseq:NP_817124.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:bTJnhl0qEm2ACoHQ7IOcn5Rx7xM9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q96S15 intact:EBI-20723690 intact:EBI-746424|uniprotkb:Q96GC7|uniprotkb:Q9H0B7|uniprotkb:A2IDB8|uniprotkb:D3DU59|ensembl:ENSP00000293883|intact:EBI-11086802 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:wdr24_human(display_long)|uniprotkb:WDR24(gene name)|psi-mi:WDR24(display_short)|uniprotkb:C16orf21(gene name synonym)|uniprotkb:WD repeat-containing protein 24(gene name synonym)|uniprotkb:JFP7(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_115635.1|ensembl:ENSG00000127580(gene)|ensembl:ENST00000293883(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061700"(GATOR2 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037590|reactome:R-HSA-9639288|dip:DIP-53812N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:t4jmiY8uryt3X3y5QUGYRMGFpXg9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:O95163 intact:EBI-20723690 intact:EBI-347559|uniprotkb:Q9H327|uniprotkb:Q9UG87|uniprotkb:Q5JSV2|ensembl:ENSP00000363779|ensembl:ENSP00000501893 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:elp1_human(display_long)|uniprotkb:ELP1(gene name)|psi-mi:ELP1(display_short)|uniprotkb:IKAP(gene name synonym)|uniprotkb:IKBKAP(gene name synonym)|uniprotkb:p150(gene name synonym)|uniprotkb:IkappaB kinase complex-associated protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) dip:DIP-27579N|refseq:NP_003631.2|refseq:NP_001305289.1|ensembl:ENSG00000070061(gene)|ensembl:ENST00000374647(transcript)|ensembl:ENST00000675406(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR006849(IKI3)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O95163|rcsb pdb:5CQR|reactome:R-HSA-3214847|go:"GO:0005829"(cytosol) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:hl+inV6TcN+DGu9CwE3SitkHiI09606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q13535-2 intact:EBI-20723690 intact:EBI-20723681|ensembl:ENSP00000499589 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q13535-2(display_long)|uniprotkb:ATR(gene name)|psi-mi:ATR(display_short)|uniprotkb:FRP1(gene name synonym)|uniprotkb:Ataxia telangiectasia and Rad3-related protein(gene name synonym)|uniprotkb:FRAP-related protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000175054(gene)|ensembl:ENST00000661310(transcript)|intact:EBI-968983(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:cuyS83EPCdB4+zOswQGEggxn31I9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P83111 intact:EBI-20723690 intact:EBI-2878119|ensembl:ENSP00000261893|uniprotkb:P83096 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:lactb_human(display_long)|uniprotkb:LACTB(gene name)|psi-mi:LACTB(display_short)|uniprotkb:MRPL56(gene name synonym)|uniprotkb:UNQ843/PRO1781(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000103642(gene)|ensembl:ENST00000261893(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|refseq:NP_116246.2|refseq:NP_741982.1|refseq:NP_001275514.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:idqlmN9YYs76X8+d8+4LALz5WjM9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:K4DI86 intact:EBI-20723690 intact:EBI-20723806 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:k4di86_human(display_long)|uniprotkb:ABCC9(gene name)|psi-mi:ABCC9(display_short)|uniprotkb:hCG_24790(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) go:"GO:0005524"(ATP binding)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008281"(sulfonylurea receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR036640|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR001475(Sulphonylurea receptor, type 2, N-terminus)|interpro:IPR027417|interpro:IPR000388(Sulphonylurea receptor, N-terminus) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:4LDB9MGv3Nj1XXg95ilUxdtHB909606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:E9PF10 intact:EBI-20723690 intact:EBI-10966422|ensembl:ENSP00000422019 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pf10_human(display_long)|uniprotkb:NUP155(gene name)|psi-mi:NUP155(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_001265241.1|ensembl:ENSG00000113569(gene)|ensembl:ENST00000513532(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042537|interpro:IPR042538 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:MVzd8diq4txjpvuviCQJte4Qjgk9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q00341 intact:EBI-20723690 intact:EBI-1049478|uniprotkb:Q9UCY3|uniprotkb:Q53QU2|uniprotkb:B4DTQ2|uniprotkb:E7EM71|intact:EBI-28974616|ensembl:ENSP00000399139 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:vigln_human(display_long)|uniprotkb:High density lipoprotein-binding protein(gene name synonym)|uniprotkb:HDLBP(gene name)|psi-mi:HDLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:VGL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSP00000399139|refseq:NP_005327.1|refseq:NP_976221.1|refseq:NP_001230829.1|refseq:XP_011509360.1|refseq:XP_011509362.1|refseq:XP_016859429.1|ensembl:ENSG00000115677(gene)|ensembl:ENST00000427183(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0045296"(cadherin binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|rcsb pdb:1VIG|rcsb pdb:1VIH|rcsb pdb:2CTE|rcsb pdb:2CTF|rcsb pdb:2CTJ|rcsb pdb:2CTK|rcsb pdb:2CTL|rcsb pdb:2CTM|reactome:R-HSA-8964011|refseq:NP_001307894.1|refseq:NP_001307895.1|refseq:XP_005247059.2|refseq:XP_006712538.1|refseq:XP_005247060.2 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:4NqKFEjUn5Fi5Ws3tirpanGqYwg9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:O15269 intact:EBI-20723690 intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:E9PNW8 intact:EBI-20723690 intact:EBI-20723046|ensembl:ENSP00000437111 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pnw8_human(display_long)|uniprotkb:FAR1(gene name)|psi-mi:FAR1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000197601(gene)|ensembl:ENST00000532701(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0080019"("fatty-acyl-CoA reductase (alcohol-forming) activity")|go:"GO:0102965"(alcohol-forming fatty acyl-CoA reductase activity)|interpro:IPR013120(Male sterility, NAD-binding)|interpro:IPR026055|interpro:IPR036291 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:+JHdLhoNtynywYk+gSS7KHYJqQg9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9P086 intact:EBI-20723690 intact:EBI-394704|uniprotkb:Q6NS89|ensembl:ENSP00000293777 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med11_human(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)|uniprotkb:HSPC296(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_001291929.1|refseq:NP_001001683.1|ensembl:ENSG00000161920(gene)|ensembl:ENST00000293777(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019404|mint:Q9P086|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|go:"GO:0003712"(transcription coregulator activity) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:y7SZi5hIo5aOatJSZi98Hqt082A9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q12824-2 intact:EBI-20723690 intact:EBI-358436|ensembl:ENSP00000383984|ensembl:ENSP00000486870 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q12824-2(display_long)|uniprotkb:INI1B(isoform synonym)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:BAF47(gene name synonym)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000407422(transcript)|ensembl:ENST00000631333(transcript)|intact:EBI-358419(snf5_human)|uniprotkb:Q12824-2(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:nCACo1KHiMlwp3pROvLzVFOl5pE9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q92784 intact:EBI-20723690 intact:EBI-16355309|ensembl:ENSP00000450518|uniprotkb:A8MSI3|uniprotkb:B7Z276|uniprotkb:F5H575|uniprotkb:Q32UJ0|uniprotkb:Q6P9E6|uniprotkb:Q6ZT41|uniprotkb:Q9H7Y5 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:dpf3_human(display_long)|uniprotkb:DPF3(gene name)|psi-mi:DPF3(display_short)|uniprotkb:BAF45C(gene name synonym)|uniprotkb:BRG1-associated factor 45C(gene name synonym)|uniprotkb:CERD4(gene name synonym)|uniprotkb:Zinc finger protein cer-d4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000205683(gene)|ensembl:ENST00000556509(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071565"(nBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|interpro:IPR038047|mint:Q92784|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:5I3L|rcsb pdb:5SZB|rcsb pdb:5SZC|go:"GO:0007399"(nervous system development)|dip:DIP-59245N|refseq:NP_001267471.1|refseq:NP_001267472.1|refseq:NP_001267473.1|refseq:NP_036206.3|refseq:XP_016877159.1|refseq:XP_016877160.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:O97+tk0b//PukSNQS/JTPszyqbU9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9Y597 intact:EBI-20723690 intact:EBI-373299|uniprotkb:A0AV15|uniprotkb:Q49AG7|uniprotkb:Q504Q9|uniprotkb:Q6PJN6|uniprotkb:Q8ND58|uniprotkb:Q8NDJ0|uniprotkb:Q8WX16|uniprotkb:D3DTA6|ensembl:ENSP00000259154 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:kctd3_human(display_long)|uniprotkb:KCTD3(gene name)|psi-mi:KCTD3(display_short)|uniprotkb:Renal carcinoma antigen NY-REN-45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_057205.2|refseq:NP_001306223.1|refseq:NP_001306224.1|ensembl:ENST00000259154(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-HSA-9013148|ensembl:ENSG00000136636(gene) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:rd5uwUaxsHyv815HcLJmrI3sgNQ9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9Y5V3-2 intact:EBI-20723690 intact:EBI-16812862 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9y5v32(display_long)|uniprotkb:PP2250(orf name)|uniprotkb:PRO2292(orf name)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) uniprotkb:Q9Y5V3-2(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:BMWcQEWXLa1tlUMwjwBL34RRH9E9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q63HN8 intact:EBI-20723690 intact:EBI-1058832|intact:EBI-1059339|uniprotkb:Q8TEU0|uniprotkb:Q9H6C9|uniprotkb:C9JCP4|uniprotkb:D6RI12|uniprotkb:F8WKS1|uniprotkb:Q658P6|uniprotkb:Q6MZR1|uniprotkb:Q9H6H9|uniprotkb:Q9H6P3|uniprotkb:Q9H8A9|uniprotkb:Q9HCF4|uniprotkb:Q9HCL8|uniprotkb:Q69YK7|uniprotkb:Q8IWF4|uniprotkb:Q8IZX1|uniprotkb:Q8IZX2|uniprotkb:Q8N406 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rn213_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF213(gene name synonym)|uniprotkb:RNF213(gene name)|psi-mi:RNF213(display_short)|uniprotkb:ALK lymphoma oligomerization partner on chromosome 17(gene name synonym)|uniprotkb:ALO17(gene name synonym)|uniprotkb:C17orf27(gene name synonym)|uniprotkb:KIAA1554(gene name synonym)|uniprotkb:KIAA1618(gene name synonym)|uniprotkb:MYSTR(gene name synonym)|uniprotkb:Mysterin(gene name synonym)|uniprotkb:RING finger protein 213(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018957|go:"GO:0001525"(angiogenesis)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000051"(negative regulation of non-canonical Wnt signaling pathway)|reactome:R-HSA-9635465|reactome:R-HSA-983168|refseq:NP_001243000.2|interpro:IPR027417|refseq:NP_066005.2|ensembl:ENST00000319921|ensembl:ENSP00000324392|ensembl:ENSG00000173821|interpro:IPR031248|mint:Q63HN8 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:M5TG5F1xZSNNeYTLh0H6WMqUHGs9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9Y2X0-2 intact:EBI-20723690 intact:EBI-10970047|ensembl:ENSP00000379153 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9y2x0-2(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) intact:EBI-394541(isoform-parent)|ensembl:ENSG00000175221(gene)|ensembl:ENST00000395808(transcript)|uniprotkb:Q9Y2X0-2(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:FDFwyztYm5BxsnasSg/tAwUFeOY9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P04049 intact:EBI-20723690 intact:EBI-365996|uniprotkb:B0LPH8|uniprotkb:Q15278|uniprotkb:Q9UC20|ensembl:ENSP00000251849|uniprotkb:B2R5N3 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:raf1_human(display_long)|uniprotkb:RAF1(gene name)|psi-mi:RAF1(display_short)|uniprotkb:RAF(gene name synonym)|uniprotkb:Proto-oncogene c-RAF(gene name synonym)|uniprotkb:Raf-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) rcsb pdb:3IQV|rcsb pdb:3KUC|rcsb pdb:3KUD|rcsb pdb:3NKX|rcsb pdb:3O8I|rcsb pdb:3OMV|rcsb pdb:4FJ3|rcsb pdb:4G0N|rcsb pdb:4G3X|rcsb pdb:4IEA|rcsb pdb:4IHL|rcsb pdb:6NTC|rcsb pdb:6NTD|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6VJJ|rcsb pdb:6XGU|rcsb pdb:6XGV|rcsb pdb:6XHA|rcsb pdb:6XHB|rcsb pdb:6XI7|ensembl:ENSG00000132155(gene)|ensembl:ENST00000251849(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007507"(heart development)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0060324"(face development)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR003116(Raf-like Ras-binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020454|interpro:IPR029071|mint:P04049|rcsb pdb:1C1Y|rcsb pdb:1FAQ|rcsb pdb:1FAR|rcsb pdb:1GUA|rcsb pdb:1RFA|rcsb pdb:3CU8|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:7JHP|reactome:R-HSA-2672351|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-5621575|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|refseq:NP_002871.1|refseq:XP_011532276.1|refseq:XP_005265412.1|dip:DIP-1048N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:1WOAPuzcZdMoq9hyFD/qr4Tz7049606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9NYJ8 intact:EBI-20723690 intact:EBI-358708|uniprotkb:O94838|uniprotkb:Q6I9W8|uniprotkb:Q76N06|uniprotkb:Q9UFP7|uniprotkb:E1P5A0|uniprotkb:B2RCC4|ensembl:ENSP00000356426|ensembl:ENSP00000445752|ensembl:ENSP00000490618 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:tab2_human(display_long)|uniprotkb:TAB2(gene name)|psi-mi:TAB2(display_short)|uniprotkb:KIAA0733(gene name synonym)|uniprotkb:MAP3K7IP2(gene name synonym)|uniprotkb:TAK1-binding protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 2(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_055908.1|refseq:NP_001278963.1|refseq:NP_001278964.1|refseq:XP_011533935.1|ensembl:ENST00000637181(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENST00000538427(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007507"(heart development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR036443|interpro:IPR041911|mint:Q9NYJ8|rcsb pdb:2DAE|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1|reactome:R-HSA-1251985|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|ensembl:ENST00000367456(transcript)|ensembl:ENSG00000055208(gene)|refseq:XP_016866080.1|refseq:XP_016866081.1|dip:DIP-27525N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:hMWL5GobXJSsm8ToWVBF/ZwPX3M9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9Y6K5 intact:EBI-20723690 intact:EBI-6115729|uniprotkb:Q2HJ14|uniprotkb:Q9H3P5|ensembl:ENSP00000228928 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:oas3_human(display_long)|uniprotkb:OAS3(gene name)|psi-mi:OAS3(display_short)|uniprotkb:p100 OAS(gene name synonym)|uniprotkb:P/OKcl.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_006178.2|ensembl:ENSG00000111331(gene)|ensembl:ENST00000228928(transcript)|go:"GO:0001730"(2'-5'-oligoadenylate synthetase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035395"("negative regulation of chemokine (C-X-C motif) ligand 9 production")|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0060700"(regulation of ribonuclease activity)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071659"(negative regulation of IP-10 production)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR002934(Nucleotidyltransferase)|interpro:IPR006116(2-5-oligoadenylate synthetase, ubiquitin-like region)|interpro:IPR006117(2-5-oligoadenylate synthetase, conserved site)|interpro:IPR018952|interpro:IPR026774|interpro:IPR043518|interpro:IPR043519|rcsb pdb:4S3N|reactome:R-HSA-877300|reactome:R-HSA-8983711|reactome:R-HSA-909733 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:7/yDwZr/Wibns/WevqiaT7bCskY9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P23142-3 intact:EBI-20723690 intact:EBI-20722901|ensembl:ENSP00000393812 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p23142-3(display_long)|uniprotkb:FBLN1(gene name)|psi-mi:FBLN1(display_short)|uniprotkb:PP213(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000077942(gene)|ensembl:ENST00000442170(transcript)|uniprotkb:P23142-3(isoform-parent)|intact:EBI-726652(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:LlNjk4lysFMyAtlGZJ3zW2tmXs89606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9NVC6 intact:EBI-20723690 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P51532-5 intact:EBI-20723690 intact:EBI-20723796 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p51532-5(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) uniprotkb:P51532-5(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:fcW7idAR3uPI6/FHFABGbPpBQ5k9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P49458 intact:EBI-20723690 intact:EBI-350743|uniprotkb:Q6NVX0|uniprotkb:Q8WTW0|ensembl:ENSP00000305230|uniprotkb:A8K0N0 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:srp09_human(display_long)|uniprotkb:SRP9(gene name)|psi-mi:SRP9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) rcsb pdb:4UYJ|refseq:NP_001123912.1|refseq:NP_003124.1|ensembl:ENSG00000143742(gene)|ensembl:ENST00000304786(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|mint:P49458|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-6151N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:Y33fEeeXnma9oF7Fzs6zEGQjVBU9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q6P2C8-2 intact:EBI-20723690 intact:EBI-20722874 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q6p2c8-2(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) uniprotkb:Q6P2C8-2(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:lDlawjPj7PITZ0nJSDAT8/gnG589606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9H944 intact:EBI-20723690 intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:H0YJH0 intact:EBI-20723690 intact:EBI-20723780|ensembl:ENSP00000451492 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:h0yjh0_human(display_long)|uniprotkb:SAV1(gene name)|psi-mi:SAV1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000151748(gene)|ensembl:ENST00000555720(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0035329"(hippo signaling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:yonntwRLClP8RGyXzPH2ugdgK9I9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q4G0J3 intact:EBI-20723690 intact:EBI-2371923|uniprotkb:B2ZHN6|uniprotkb:Q3B7A9|uniprotkb:Q9P1S7|uniprotkb:Q9Y3Z8|intact:EBI-2560173|ensembl:ENSP00000314311|ensembl:ENSP00000344950|ensembl:ENSP00000499190 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:larp7_human(display_long)|uniprotkb:LARP7(gene name)|psi-mi:LARP7(display_short)|uniprotkb:La ribonucleoprotein domain family member 7(gene name synonym)|uniprotkb:P-TEFb-interaction protein for 7SK stability(gene name synonym)|uniprotkb:HDCMA18P(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_056269.1|refseq:NP_057732.2|refseq:NP_001253968.1|dip:DIP-47624N|ensembl:ENSG00000174720(gene)|ensembl:ENST00000324052(transcript)|ensembl:ENST00000344442(transcript)|ensembl:ENST00000651579(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990438"(U6 2'-O-snRNA methylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR034887|interpro:IPR034910|interpro:IPR034946|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:Q4G0J3|rcsb pdb:4WKR|rcsb pdb:5KNW|rcsb pdb:6D12 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:ZIHCyGk7VI4irQOPvTXcNjk2ifw9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:O00468-6 intact:EBI-20723690 intact:EBI-17740588 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:o004686(display_long)|uniprotkb:AGRN(gene name)|psi-mi:AGRN(display_short)|uniprotkb:AGRIN(gene name synonym)|uniprotkb:"Agrin y(0)z(0)"(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) uniprotkb:O00468-6(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:TEWFASMxNxh6H0Y5Z5NRw/BEMD49606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P67775 intact:EBI-20723690 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q5JWT2 intact:EBI-20723690 intact:EBI-20722806|ensembl:ENSP00000357037 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q5jwt2_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:Mediator of RNA polymerase II transcription subunit 23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000112282(gene)|ensembl:ENST00000368058(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR021629 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:H/D6RDJdrHK9Z70jzqDwt0BUzy49606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9P2N7-2 intact:EBI-20723690 intact:EBI-20722815|ensembl:ENSP00000440707 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9p2n7-2(display_long)|uniprotkb:KLHL13(gene name)|psi-mi:KLHL13(display_short)|uniprotkb:BKLHD2(gene name synonym)|uniprotkb:KIAA1309(gene name synonym)|uniprotkb:BTB and kelch domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000003096(gene)|ensembl:ENST00000545703(transcript)|uniprotkb:Q9P2N7-2(isoform-parent)|intact:EBI-1996321(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:2MRL3spWcfrnua6TB1wE19S6IHY9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:O60568 intact:EBI-20723690 intact:EBI-741582|uniprotkb:Q540C3|ensembl:ENSP00000223127|uniprotkb:B2R6W6 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:plod3_human(display_long)|uniprotkb:PLOD3(gene name)|psi-mi:PLOD3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000106397(gene)|ensembl:ENST00000223127(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005506"(iron ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0008104"(protein localization)|go:"GO:0008475"(procollagen-lysine 5-dioxygenase activity)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0021915"(neural tube development)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033823"(procollagen glucosyltransferase activity)|go:"GO:0042311"(vasodilation)|go:"GO:0046947"(hydroxylysine biosynthetic process)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050211"(procollagen galactosyltransferase activity)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR001006(Procollagen-lysine 5-dioxygenase)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR029044|mint:O60568|rcsb pdb:6FXK|rcsb pdb:6FXM|rcsb pdb:6FXR|rcsb pdb:6FXT|rcsb pdb:6FXX|rcsb pdb:6FXY|rcsb pdb:6TE3|rcsb pdb:6TEC|refseq:NP_001075.1|rcsb pdb:6TES|rcsb pdb:6TEU|rcsb pdb:6TEX|rcsb pdb:6TEZ|reactome:R-HSA-1650814|rcsb pdb:6WFV - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:dvfk+ko7squrB6c4AayW+fR8EnE9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:F5H793 intact:EBI-20723690 intact:EBI-20722822|ensembl:ENSP00000442680 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:f5h793_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000111716(gene)|ensembl:ENST00000539782(transcript)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0019752"(carboxylic acid metabolic process)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR036291 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:xxKQBT7kJ4YGikY2geFfrEz2pBc9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:O14841 intact:EBI-20723690 intact:EBI-3938544|uniprotkb:Q9Y4Q0|uniprotkb:Q75W65|uniprotkb:A5PKY8|ensembl:ENSP00000480476 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:opla_human(display_long)|uniprotkb:OPLAH(gene name)|psi-mi:OPLAH(display_short)|uniprotkb:5-oxo-L-prolinase(gene name synonym)|uniprotkb:Pyroglutamase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000178814(gene)|ensembl:ENST00000618853(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0017168"("5-oxoprolinase (ATP-hydrolyzing) activity")|go:"GO:0042802"(identical protein binding)|interpro:IPR002821(Hydantoinase/oxoprolinase)|interpro:IPR003692(Hydantoinase B/oxoprolinase)|interpro:IPR008040(Hydantoinaseoxoprolinase, N-terminal)|mint:O14841|reactome:R-HSA-174403|reactome:R-HSA-5578998|refseq:NP_060040.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:9Y4toRkLUqqb+G4+sCVzpeBZe8c9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:D6RGG3 intact:EBI-20723690 intact:EBI-11119619|ensembl:ENSP00000421216 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:d6rgg3_human(display_long)|uniprotkb:COL12A1(gene name)|psi-mi:COL12A1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000111799(gene)|ensembl:ENST00000483888(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|interpro:IPR001791(Laminin G)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036465 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:ih2KMs3glmK7rLb8QRFFjn3852s9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q4TT34 intact:EBI-20723690 intact:EBI-20723763|ensembl:ENSP00000372398 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q4tt34_human(display_long)|uniprotkb:NME4(gene name)|psi-mi:NME4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000103202(gene)|ensembl:ENST00000382940(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:Rc6mK/KhXbFOkDGGJF3dGgfSwRo9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q96JB6 intact:EBI-20723690 intact:EBI-749562|uniprotkb:Q96DY1|uniprotkb:Q96PC0|uniprotkb:Q9H6T5|uniprotkb:Q5W0B3|ensembl:ENSP00000260702 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:loxl4_human(display_long)|uniprotkb:Lysyl oxidase-like protein 4(gene name synonym)|uniprotkb:Lysyl oxidase-related protein C(gene name synonym)|uniprotkb:LOXL4(gene name)|psi-mi:LOXL4(display_short)|uniprotkb:LOXC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_115587.6|ensembl:ENSG00000138131(gene)|ensembl:ENST00000260702(transcript)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0016020"(membrane)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR019828|interpro:IPR036772|mint:Q96JB6|reactome:R-HSA-1566948|reactome:R-HSA-2243919 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:yOUffU5WqmaUNvrXvX1ie0RWEG49606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:C9JRD2 intact:EBI-20723690 intact:EBI-20723752|ensembl:ENSP00000414796 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:c9jrd2_human(display_long)|uniprotkb:DNAJB2(gene name)|psi-mi:DNAJB2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000135924(gene)|ensembl:ENST00000425450(transcript)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|interpro:IPR043183 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:YrYWafeuImDjusN8pZIZoJ87vyA9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:O15230 intact:EBI-20723690 intact:EBI-725060|uniprotkb:Q8WZA7|uniprotkb:Q9H1P1|uniprotkb:Q8TDF8|uniprotkb:Q5U4N9|ensembl:ENSP00000252999 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:lama5_human(display_long)|uniprotkb:LAMA5(gene name)|psi-mi:LAMA5(display_short)|uniprotkb:KIAA0533(gene name synonym)|uniprotkb:KIAA1907(gene name synonym)|uniprotkb:Laminin-10 subunit alpha(gene name synonym)|uniprotkb:Laminin-11 subunit alpha(gene name synonym)|uniprotkb:Laminin-15 subunit alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_005551.3|ensembl:ENSG00000130702(gene)|ensembl:ENST00000252999(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001942"(hair follicle development)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005610"(laminin-5 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016477"(cell migration)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|mint:O15230|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-6785807|reactome:R-HSA-8874081 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:rSTl5zwwQKcbd20buKGffFtl3jI9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:O00165-5 intact:EBI-20723690 intact:EBI-11107757|ensembl:ENSP00000411448 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:o00165-5(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)|uniprotkb:HS1BP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) intact:EBI-357001(isoform-parent)|ensembl:ENSG00000143575(gene)|ensembl:ENST00000457918(transcript) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:fOY3HGmianmbqvoQZs8sllSqgEE9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 intact:EBI-20723738 intact:EBI-20723690 - psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:j3knn5_human(display_short)|psi-mi:EBI-20723738(display_long)|uniprotkb:DDX41(gene name)|psi-mi:DDX41(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) uniprotkb:J3KNN5(uniprot-removed-ac) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:gRDZmJXQNQVKX4VzSihVo51LXrA9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q6AZZ1 intact:EBI-20723690 intact:EBI-2130449|uniprotkb:A6NI19|uniprotkb:A8K551|uniprotkb:Q8WZ70|uniprotkb:Q96PF7|uniprotkb:Q9H9C2|uniprotkb:Q9NW18|uniprotkb:B3KPM5|uniprotkb:Q96LE5|uniprotkb:B4DVK4|ensembl:ENSP00000300747 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:tri68_human(display_long)|uniprotkb:TRIM68(gene name)|psi-mi:TRIM68(display_short)|uniprotkb:RNF137(gene name synonym)|uniprotkb:SS56(gene name synonym)|uniprotkb:RING finger protein 137(gene name synonym)|uniprotkb:SSA protein SS-56(gene name synonym)|uniprotkb:GC109(gene name synonym)|uniprotkb:Tripartite motif-containing protein 68(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_001291425.1|refseq:NP_060543.5|ensembl:ENSG00000167333(gene)|ensembl:ENST00000300747(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042656|interpro:IPR043136|reactome:R-HSA-877300 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:hm0MRstol6cN4p4oG4p2iuQhSEo9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P11047 intact:EBI-20723690 intact:EBI-714904|uniprotkb:Q5VYE7|ensembl:ENSP00000258341 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:lamc1_human(display_long)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:LAMC1(gene name)|psi-mi:LAMC1(display_short)|uniprotkb:LAMB2(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|mint:P11047|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9619665|go:"GO:0070062"(extracellular exosome)|refseq:NP_002284.3|ensembl:ENSG00000135862(gene)|ensembl:ENST00000258341(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007492"(endoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:2JMPODzaiqmTaLlmjdgvlv8e8+M9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:H0YJ08 intact:EBI-20723690 intact:EBI-20723725|ensembl:ENSP00000450588 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:h0yj08_human(display_long)|uniprotkb:AP1G2(gene name)|psi-mi:AP1G2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000213983(gene)|ensembl:ENST00000557162(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030117"(membrane coat)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:fkvVL7I1kWhxRrNsHSPQ7jbWDzc9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:O94952-1 intact:EBI-20723690 intact:EBI-11023203|ensembl:ENSP00000483508 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:o94952-1(display_long)|uniprotkb:FBXO21(gene name)|psi-mi:FBXO21(display_short)|uniprotkb:FBX21(gene name synonym)|uniprotkb:KIAA0875(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000135108(gene)|ensembl:ENST00000622495(transcript)|intact:EBI-311435(isoform-parent)|uniprotkb:O94952-1(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:8lf2JyYa6Oj2rpFwlCtXXo5CkY09606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q8WX93 intact:EBI-20723690 intact:EBI-2803991|uniprotkb:Q9Y2J6|uniprotkb:Q9UQF5|uniprotkb:Q8N1M2|uniprotkb:Q7Z3W0|uniprotkb:Q86WE8|uniprotkb:B5MD56|uniprotkb:Q7L3E0|uniprotkb:Q9UGA0|uniprotkb:Q9Y3E9|uniprotkb:B7ZMM5|uniprotkb:B3KTG2 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:palld_human(display_long)|uniprotkb:KIAA0992(gene name synonym)|uniprotkb:SIH002(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-77(gene name synonym)|uniprotkb:CGI-151(orf name)|uniprotkb:PALLD(gene name)|psi-mi:PALLD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) interpro:IPR033017|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0060076"(excitatory synapse)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|rcsb pdb:2DM2|rcsb pdb:2DM3|go:"GO:0016477"(cell migration)|refseq:NP_001159580.1|refseq:NP_001159581.1|refseq:NP_001159582.1|refseq:NP_057165.3|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR036179|mint:Q8WX93 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:0GUVyoDYzf03b+bZXUa1n/fnP/Y9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P50454 intact:EBI-20723690 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P55268 intact:EBI-20723690 intact:EBI-2529769|uniprotkb:Q16321|ensembl:ENSP00000307156|ensembl:ENSP00000388325 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:lamb2_human(display_long)|uniprotkb:Laminin-4 subunit beta(gene name synonym)|uniprotkb:Laminin-7 subunit beta(gene name synonym)|uniprotkb:Laminin-9 subunit beta(gene name synonym)|uniprotkb:Laminin-11 subunit beta(gene name synonym)|uniprotkb:Laminin-14 subunit beta(gene name synonym)|uniprotkb:Laminin-15 subunit beta(gene name synonym)|uniprotkb:S-laminin subunit beta(gene name synonym)|uniprotkb:LAMB2(gene name)|psi-mi:LAMB2(display_short)|uniprotkb:LAMS(gene name synonym)|uniprotkb:Laminin-3 subunit beta(gene name synonym)|uniprotkb:Laminin B1s chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000172037(gene)|ensembl:ENST00000305544(transcript)|ensembl:ENST00000418109(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005608"(laminin-3 complex)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014002"(astrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016477"(cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043256"(laminin complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0048677"(axon extension involved in regeneration)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|go:"GO:0072249"(metanephric glomerular visceral epithelial cell development)|go:"GO:0072274"(metanephric glomerular basement membrane development)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P55268|reactome:R-HSA-3000157|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-3000171|refseq:NP_002283.3|refseq:XP_005265184.1|dip:DIP-42106N - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:LY1lt2hyTcFN+x4GtvfzufChDF89606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P35228-2 intact:EBI-20723690 intact:EBI-20722728 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:p35228-2(display_long)|uniprotkb:NOS2(gene name)|psi-mi:NOS2(display_short)|uniprotkb:NOS2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) uniprotkb:P35228-2(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:rKFr1Md01jNBgnv2ah/hJJUGU8o9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q8N5L8 intact:EBI-20723690 intact:EBI-10189722|uniprotkb:D3DRM5|ensembl:ENSP00000297613|ensembl:ENSP00000368242 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rp25l_human(display_long)|uniprotkb:RPP25L(gene name)|psi-mi:RPP25L(display_short)|uniprotkb:C9orf23(gene name synonym)|uniprotkb:Rpp25-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_680544.1|refseq:NP_680545.1|ensembl:ENSG00000164967(gene)|ensembl:ENST00000297613(transcript)|ensembl:ENST00000378959(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|interpro:IPR002775(Alba, DNA/RNA-binding protein)|interpro:IPR036882 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:WpTe4D9lvRLa+96z7U42c722f2A9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:E9PIR7 intact:EBI-20723690 intact:EBI-20723555|ensembl:ENSP00000433935 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:e9pir7_human(display_long)|uniprotkb:TXNRD1(gene name)|psi-mi:TXNRD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000198431(gene)|ensembl:ENST00000527688(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:W7Kn+mfDVYACMOU1dz/qITv6BQk9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:M0R081 intact:EBI-20723690 intact:EBI-20723718|ensembl:ENSP00000471075 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:m0r081_human(display_long)|uniprotkb:CLEC11A(gene name)|psi-mi:CLEC11A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000105472(gene)|ensembl:ENST00000599973(transcript) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:WiVNE0zf2orMdmATRJ0cmeHj66A9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q8NDN9 intact:EBI-20723690 intact:EBI-2811558|uniprotkb:Q969U9|intact:EBI-3044072|uniprotkb:Q8IY29|ensembl:ENSP00000258646|ensembl:ENSP00000367552 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:rcbt1_human(display_long)|uniprotkb:RCBTB1(gene name)|psi-mi:RCBTB1(display_short)|uniprotkb:CLLD7(gene name synonym)|uniprotkb:E4.5(gene name synonym)|uniprotkb:Chronic lymphocytic leukemia deletion region gene 7 protein(gene name synonym)|uniprotkb:Regulator of chromosome condensation and BTB domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:XP_011533435.1|refseq:XP_011533436.1|refseq:NP_060661.3|ensembl:ENSG00000136144(gene)|ensembl:ENST00000258646(transcript)|ensembl:ENST00000378302(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011333(BTB/POZ fold)|refseq:XP_005266498.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:qlFRfKV0PffERWU2HnbL6M64qa09606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:P58107 intact:EBI-20723690 intact:EBI-297954|uniprotkb:Q76E58|ensembl:ENSP00000484472|uniprotkb:A0A087X1U6|uniprotkb:Q9NSU9 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:epipl_human(display_long)|uniprotkb:EPPK1(gene name)|psi-mi:EPPK1(display_short)|uniprotkb:EPIPL(gene name synonym)|uniprotkb:450 kDa epidermal antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSP00000484472|ensembl:ENSG00000261150(gene)|ensembl:ENST00000615648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042060"(wound healing)|go:"GO:0042995"(cell projection)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051548"(negative regulation of keratinocyte migration)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0071944"(cell periphery)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1905041"(regulation of epithelium regeneration)|go:"GO:1990254"(keratin filament binding)|interpro:IPR001101(Plectin repeat)|interpro:IPR035915|interpro:IPR043197|refseq:NP_112598.3|refseq:XP_016869379.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:5ThrRQj4JeRG4xjZxMgueWUrjuA9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q8WTU2 intact:EBI-20723690 intact:EBI-20722735|ensembl:ENSP00000275560|uniprotkb:Q2HIZ5|uniprotkb:Q6ZMG3|uniprotkb:Q96BF5 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:srb4d_human(display_long)|uniprotkb:Four scavenger receptor cysteine-rich domains-containing protein(gene name synonym)|uniprotkb:S4D-SRCRB(gene name synonym)|uniprotkb:SSC4D(gene name)|psi-mi:SSC4D(display_short)|uniprotkb:SRCRB4D(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|ensembl:ENSG00000146700(gene)|ensembl:ENST00000275560(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|refseq:NP_542782.1 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:FnulMrTXfb92o1AC8HOEBWxDLxo9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9NY57-2 intact:EBI-20723690 intact:EBI-20723711 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:q9ny57-2(display_long)|uniprotkb:STK32B(gene name)|psi-mi:STK32B(display_short)|uniprotkb:YANK2(gene name synonym)|uniprotkb:UNQ3003/PRO9744(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) uniprotkb:Q9NY57-2(isoform-parent) - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:49M23o4WJdK7HuGeZ1BuWdqH05k9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:H3BM89 intact:EBI-20723690 intact:EBI-20723696|ensembl:ENSP00000454281 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:h3bm89_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:hCG_2004318(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) ensembl:ENSG00000174444(gene)|ensembl:ENST00000568588(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR023574|interpro:IPR025755 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:E61rJaaOnUZaWhqmEdE6MjCVAxI9606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q9Y6N5 intact:EBI-20723690 intact:EBI-1170418|uniprotkb:Q9UQM8|ensembl:ENSP00000260324|ensembl:ENSP00000456019 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:sqor_human(display_long)|uniprotkb:SQOR(gene name)|psi-mi:SQOR(display_short)|uniprotkb:SQRDL(gene name synonym)|uniprotkb:Sulfide quinone oxidoreductase(gene name synonym)|uniprotkb:CGI-44(orf name)|uniprotkb:Sulfide dehydrogenase-like(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_067022.1|refseq:NP_001258142.1|ensembl:ENSG00000137767(gene)|ensembl:ENST00000260324(transcript)|ensembl:ENST00000568606(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0048038"(quinone binding)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0070224"("sulfide:quinone oxidoreductase activity")|go:"GO:0070813"(hydrogen sulfide metabolic process)|go:"GO:0071949"(FAD binding)|interpro:IPR015904(Sulphide quinone-reductase)|interpro:IPR023753|interpro:IPR036188|mint:Q9Y6N5|rcsb pdb:6MO6|rcsb pdb:6MP5|rcsb pdb:6OI5|rcsb pdb:6OI6|rcsb pdb:6OIB|rcsb pdb:6OIC|rcsb pdb:6WH6|reactome:R-HSA-1614517 - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:bjOY0YAzon+joBQnCx3q9YvSHh49606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RS6-3 uniprotkb:Q12756 intact:EBI-20723690 intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824 psi-mi:q96rs6-3(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723859|imex:IM-26492-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2512429(isoform-parent) refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR - isoform-comment:May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. - figure legend:f3 st1|comment:the proteins corresponding to the uniprot IDs J3KPZ3, H7C497, provided by authors in supplementary table 1, were not included because they have been deleted in uniprot.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2019/07/08 rogid:QIQINbSqLcWcBzupOYOx1cGp8Nw9606 rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606 rigid:QgJYi0VXuJYdtLV/q81urOLFopY false green fluorescent protein tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q9Y4K0 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-7172227|ensembl:ENSP00000373783|intact:MINT-4053647|uniprotkb:Q9BW70|uniprotkb:Q53HV3|uniprotkb:Q9Y5Y8|uniprotkb:B2R5Q0 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:loxl2_human(display_long)|uniprotkb:LOXL2(gene name)|psi-mi:LOXL2(display_short)|uniprotkb:Lysyl oxidase-like protein 2(gene name synonym)|uniprotkb:Lysyl oxidase-related protein 2(gene name synonym)|uniprotkb:Lysyl oxidase-related protein WS9-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) ensembl:ENSG00000134013(gene)|ensembl:ENST00000389131(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007155"(cell adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0007568"(aging)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046688"(response to copper ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0070828"(heterochromatin organization)|go:"GO:1902455"(negative regulation of stem cell population maintenance)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR019828|interpro:IPR036772|mint:Q9Y4K0|rcsb pdb:5ZE3|reactome:R-HSA-1566948|reactome:R-HSA-2243919|go:"GO:0030199"(collagen fibril organization)|refseq:NP_002309.1 - - comment:mint figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:F7xjdY5T+JdpyIAsi2BmXPzqz+A9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q13347 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-354047|intact:EBI-11759480|ensembl:ENSP00000504034|ensembl:ENSP00000504061|ensembl:ENSP00000502867|ensembl:ENSP00000503348|ensembl:ENSP00000503539 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:eif3i_human(display_long)|uniprotkb:EIF3I(gene name)|psi-mi:EIF3I(display_short)|uniprotkb:TRIP1(gene name synonym)|uniprotkb:EIF3S2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_003748.1|ensembl:ENST00000676801(transcript)|ensembl:ENST00000677202(transcript)|ensembl:ENST00000677701(transcript)|ensembl:ENST00000677711(transcript)|ensembl:ENST00000677760(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|ensembl:ENSG00000084623(gene)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q13347|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31116N - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:fogC6nSNmIynV2ziHZboT9laA3M9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q15393 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q9Y3B4 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-1046261|ensembl:ENSP00000233468|uniprotkb:Q53TM1 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:sf3b6_human(display_long)|uniprotkb:SF3B6(gene name)|psi-mi:SF3B6(display_short)|uniprotkb:Pre-mRNA branch site protein p14(gene name synonym)|uniprotkb:SAP14(gene name synonym)|uniprotkb:SF3B14(gene name synonym)|uniprotkb:SF3B14A(gene name synonym)|uniprotkb:SF3b 14 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein, 14-kDa(gene name synonym)|uniprotkb:Splicing factor 3b, subunit 6, 14kDa(gene name synonym)|uniprotkb:CGI-110(orf name)|uniprotkb:HSPC175(orf name)|uniprotkb:HT006(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) ensembl:ENST00000233468(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000115128(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034150|interpro:IPR035979|mint:Q9Y3B4|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:3LQV|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_057131.1|dip:DIP-44132N - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:7mhaXkmVqjfJGPdX1UDM+kN4vNI9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q15427 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q96RS6 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-2512429|ensembl:ENSP00000239690|uniprotkb:Q96SI4|uniprotkb:B4DVX6|uniprotkb:Q8NG18|uniprotkb:Q4G130|uniprotkb:Q8NDQ5|uniprotkb:Q9BVR5 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:nudc1_human(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037895|refseq:NP_001121683.1|refseq:NP_116258.2|refseq:XP_016869399.1|refseq:XP_016869400.1 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q13435 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-749111|uniprotkb:A8K485|uniprotkb:B4DT19|uniprotkb:Q7Z627|uniprotkb:Q969K1|uniprotkb:Q96CM6|uniprotkb:Q9BWD2|intact:EBI-1052093|intact:EBI-2688256|uniprotkb:Q7L4T5|ensembl:ENSP00000318861 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:sf3b2_human(display_long)|uniprotkb:SF3B2(gene name)|psi-mi:SF3B2(display_short)|uniprotkb:SAP145(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 145 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 145(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_006833.2|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006568(PSP, proline-rich)|ensembl:ENSG00000087365(gene)|ensembl:ENST00000322535(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR007180(Protein of unknown function DUF382)|rcsb pdb:2DO5|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|mint:Q13435|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:Y9uCV2x4J5kqyxeO8iXjojkXocA9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q96JB6 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-749562|uniprotkb:Q96DY1|uniprotkb:Q96PC0|uniprotkb:Q9H6T5|uniprotkb:Q5W0B3|ensembl:ENSP00000260702 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:loxl4_human(display_long)|uniprotkb:Lysyl oxidase-like protein 4(gene name synonym)|uniprotkb:Lysyl oxidase-related protein C(gene name synonym)|uniprotkb:LOXL4(gene name)|psi-mi:LOXL4(display_short)|uniprotkb:LOXC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_115587.6|ensembl:ENSG00000138131(gene)|ensembl:ENST00000260702(transcript)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0016020"(membrane)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0043235"(receptor complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR019828|interpro:IPR036772|mint:Q96JB6|reactome:R-HSA-1566948|reactome:R-HSA-2243919 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:yOUffU5WqmaUNvrXvX1ie0RWEG49606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:P09661 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-876439|uniprotkb:Q8TBD2|uniprotkb:B2R5I6|ensembl:ENSP00000254193 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:ru2a_human(display_long)|uniprotkb:SNRPA1(gene name)|psi-mi:SNRPA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_003081.2|dip:DIP-625N|ensembl:ENSG00000131876(gene)|ensembl:ENST00000254193(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR044640|mint:P09661|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|reactome:R-HSA-8950505 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:tmZyAPCvMg34GY4kVc6NcnycOeE9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:O15226 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-766011|uniprotkb:Q4VC41|uniprotkb:Q9UJ91|uniprotkb:G3V1N1|ensembl:ENSP00000304803 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:nkrf_human(display_long)|uniprotkb:Transcription factor NRF(gene name synonym)|uniprotkb:Protein ITBA4(gene name synonym)|uniprotkb:NKRF(gene name)|psi-mi:NKRF(display_short)|uniprotkb:ITBA4(gene name synonym)|uniprotkb:NRF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_001166958.1|refseq:NP_001166959.1|refseq:NP_060014.2|refseq:XP_011529667.1|dip:DIP-34570N|ensembl:ENSG00000186416(gene)|ensembl:ENST00000304449(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000467(D111/G-patch)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036867|mint:O15226|rcsb pdb:6SH6|rcsb pdb:6SH7|interpro:IPR034071 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:jH7qlOvuAHKsjuOyzDpBonpgtF09606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:O75533 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-876542|ensembl:ENSP00000335321|uniprotkb:E9PCH3 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:sf3b1_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0034693"(U11/U12 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015016(Splicing factor 3B subunit 1)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|mint:O75533|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:2PEH|rcsb pdb:3LQV|rcsb pdb:4OZ1|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6N3E|refseq:NP_036565.2|dip:DIP-29411N|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-5250924|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q96I25 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q86XP3 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:P98175 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|uniprotkb:A0A0A0MR66|ensembl:ENSP00000366829 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_005667.2|refseq:NP_690595.1|refseq:NP_001191397.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033095|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|ensembl:ENSG00000182872(gene)|ensembl:ENST00000377604(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q8IWX8 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-2555370|uniprotkb:O00302|uniprotkb:Q99492|uniprotkb:Q4G0Y5|uniprotkb:Q8WU30|ensembl:ENSP00000439856 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:cherp_human(display_long)|uniprotkb:DAN26(gene name synonym)|uniprotkb:SCAF6(gene name synonym)|uniprotkb:SR-related CTD-associated factor 6(gene name synonym)|uniprotkb:ERPROT 213-21(gene name synonym)|uniprotkb:CHERP(gene name)|psi-mi:CHERP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_006378.3|ensembl:ENSG00000085872(gene)|ensembl:ENST00000546361(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007399"(nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035967|interpro:IPR039037|reactome:R-HSA-72163 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:Snifq3RgcsxZ8r9MCExHeb242Ss9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q12874 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:fNjNguUOXqApr46rOAEpTs2geqY9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:P08579 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-1053651|uniprotkb:Q9UJD4|uniprotkb:B2R7J3|uniprotkb:D3DW21|ensembl:ENSP00000246071|ensembl:ENSP00000367178 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:ru2b_human(display_long)|uniprotkb:SNRPB2(gene name)|psi-mi:SNRPB2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_003083.1|refseq:NP_937863.1|ensembl:ENSG00000125870(gene)|ensembl:ENST00000246071(transcript)|ensembl:ENST00000377943(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070990"(snRNP binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034562|interpro:IPR034564|interpro:IPR035979|mint:P08579|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:AzDL3wfFG4HmOfTs8NJL6bWjgrc9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q15459 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q9Y676 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-750085|uniprotkb:Q9BS27|uniprotkb:A6NDQ0|uniprotkb:Q659G4|intact:EBI-1050511|ensembl:ENSP00000259873|ensembl:ENSP00000383438|ensembl:ENSP00000397790|ensembl:ENSP00000398494|ensembl:ENSP00000402718|ensembl:ENSP00000414972|ensembl:ENSP00000415703 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:rt18b_human(display_long)|uniprotkb:28S ribosomal protein S18-2, mitochondrial(gene name synonym)|uniprotkb:C6orf14(gene name synonym)|uniprotkb:MRPS18B(gene name)|psi-mi:MRPS18B(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein bS18b(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS40(gene name synonym)|uniprotkb:HSPC183(orf name)|uniprotkb:PTD017(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_054765.1|dip:DIP-29894N|ensembl:ENSG00000203624(gene)|ensembl:ENSG00000204568(gene)|ensembl:ENSG00000223775(gene)|ensembl:ENSG00000226111(gene)|ensembl:ENSG00000227420(gene)|ensembl:ENSG00000229861(gene)|ensembl:ENSG00000233813(gene)|ensembl:ENST00000259873(transcript)|ensembl:ENST00000327800(transcript)|ensembl:ENST00000412451(transcript)|ensembl:ENST00000426945(transcript)|ensembl:ENST00000430402(transcript)|ensembl:ENST00000451032(transcript)|ensembl:ENST00000454427(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0030054"(cell junction)|go:"GO:0032543"(mitochondrial translation)|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|interpro:IPR001648(Ribosomal protein S18)|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|interpro:IPR036870|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|interpro:IPR040054|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|mint:Q9Y676 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:DFGekxKm74bAo8IWpOi8LDITWqc9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:H0Y599 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-20723950|ensembl:ENSP00000397412 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:h0y599_human(display_long)|uniprotkb:DOCK4(gene name)|psi-mi:DOCK4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR032376|interpro:IPR035769|interpro:IPR035892|interpro:IPR036028|interpro:IPR037014|interpro:IPR037811|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|ensembl:ENSG00000128512(gene)|ensembl:ENST00000445943(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity) - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:4ZdBMIC0Ir4tU4VsOW/mbaJ5XNs9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q9UBB9 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-1105213|uniprotkb:O95908|uniprotkb:Q5H8V8|uniprotkb:Q9UGV7|uniprotkb:Q9Y2Q8|ensembl:ENSP00000383892|ensembl:ENSP00000384297|ensembl:ENSP00000384421|ensembl:ENSP00000480171|ensembl:ENSP00000385861|uniprotkb:Q20WL0 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:tfp11_human(display_long)|uniprotkb:TFIP11(gene name)|psi-mi:TFIP11(display_short)|uniprotkb:HSPC006(orf name)|uniprotkb:STIP(gene name synonym)|uniprotkb:Septin and tuftelin-interacting protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) ensembl:ENSG00000100109(gene)|refseq:NP_001008697.1|refseq:NP_036275.1|go:"GO:0016607"(nuclear speck)|ensembl:ENST00000405938(transcript)|ensembl:ENST00000407148(transcript)|ensembl:ENST00000407431(transcript)|ensembl:ENST00000407690(transcript)|ensembl:ENST00000619735(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904876"(negative regulation of DNA ligase activity)|go:"GO:2001033"(negative regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000467(D111/G-patch)|interpro:IPR022159|interpro:IPR022783|interpro:IPR024933|mint:Q9UBB9|reactome:R-HSA-72163|refseq:XP_011528381.1|refseq:XP_016884224.1|refseq:NP_001333786.1|refseq:NP_001333787.1|refseq:NP_001333788.1|refseq:NP_001333790.1 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:Brk0v9dAoy5ntoJVHFsvt+FFE3g9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q8N1G2 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-2691086|uniprotkb:Q96FJ9|uniprotkb:Q14670|uniprotkb:A8K949|ensembl:ENSP00000362550 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:cmtr1_human(display_long)|uniprotkb:CMTR1(gene name)|psi-mi:CMTR1(display_short)|uniprotkb:Cap methyltransferase 1(gene name synonym)|uniprotkb:Cap1 2'O-ribose methyltransferase 1(gene name synonym)|uniprotkb:FTSJD2(gene name synonym)|uniprotkb:FtsJ methyltransferase domain-containing protein 2(gene name synonym)|uniprotkb:Interferon-stimulated gene 95 kDa protein(gene name synonym)|uniprotkb:KIAA0082(gene name synonym)|uniprotkb:MTR1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_055865.1|ensembl:ENSG00000137200(gene)|ensembl:ENST00000373451(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0080009"(mRNA methylation)|go:"GO:0097309"(cap1 mRNA methylation)|interpro:IPR000467(D111/G-patch)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR025816|interpro:IPR029063|interpro:IPR030376|mint:Q8N1G2|rcsb pdb:4N48|rcsb pdb:4N49|rcsb pdb:4N4A - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:mMoDk5J/tBCaxISq1Oju9BY0RVA9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q9BWJ5 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-2555428|uniprotkb:Q7RTV1|uniprotkb:B2R568|ensembl:ENSP00000356541 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:sf3b5_human(display_long)|uniprotkb:SF3B10(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 10 kDa subunit(gene name synonym)|uniprotkb:SF3B5(gene name)|psi-mi:SF3B5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) refseq:NP_112577.1|ensembl:ENSG00000169976(gene)|ensembl:ENST00000367569(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR009846(Splicing factor 3B subunit 5/RDS3 complex subunit 10)|interpro:IPR017089(Splicing factor 3B, subunit 5)|mint:Q9BWJ5|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5Z57 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:wuQBsSytGhSg64IQSmEJXe+26zQ9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:P16383 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-954074|ensembl:ENSP00000318690|uniprotkb:O95032|uniprotkb:Q53TY0|uniprotkb:Q6P2F2|uniprotkb:A4UHQ9|uniprotkb:A4UHQ8 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:gcfc2_human(display_long)|uniprotkb:GCFC2(gene name)|psi-mi:GCFC2(display_short)|uniprotkb:C2orf3(gene name synonym)|uniprotkb:GC-rich sequence DNA-binding factor(gene name synonym)|uniprotkb:GCF(gene name synonym)|uniprotkb:TCF9(gene name synonym)|uniprotkb:Transcription factor 9(gene name synonym)|uniprotkb:GC-rich sequence DNA-binding factor 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) ensembl:ENSG00000005436(gene)|ensembl:ENST00000321027(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071008"(U2-type post-mRNA release spliceosomal complex)|interpro:IPR022783|reactome:R-HSA-72163|interpro:IPR012890(GC-rich sequence DNA-binding factor-like)|refseq:NP_001188264.1|refseq:NP_001188263.1|refseq:NP_003194.3 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:k79JXO1or4Vrexv+VSFpxg6uDtI9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q00325 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 intact:EBI-20723938 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 - psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:h7by58_human(display_short)|psi-mi:EBI-20723938(display_long)|uniprotkb:PCMT1(gene name)|psi-mi:PCMT1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) uniprotkb:H7BY58(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:+cZySiAx2KtulFh5qKwajYbly189606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:Q86XI6 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-3918864|ensembl:ENSP00000308318|ensembl:ENSP00000428642|ensembl:ENSP00000493491|ensembl:ENSP00000494659|uniprotkb:Q9H812|uniprotkb:B3KTV3 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:ppr3b_human(display_long)|uniprotkb:PPP1R3B(gene name)|psi-mi:PPP1R3B(display_short)|uniprotkb:PPP1R4(gene name synonym)|uniprotkb:Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 4(gene name synonym)|uniprotkb:Protein phosphatase 1 subunit GL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) ensembl:ENSG00000173281(gene)|ensembl:ENSG00000285343(gene)|ensembl:ENST00000310455(transcript)|ensembl:ENST00000519699(transcript)|ensembl:ENST00000644687(transcript)|ensembl:ENST00000645121(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0042587"(glycogen granule)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050196"([phosphorylase] phosphatase activity)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR017434(Protein phosphatase 1, glycogen targeting subunit, Metazoa.)|interpro:IPR030682|interpro:IPR038175|rcsb pdb:2EEF|rcsb pdb:5ZT0|refseq:NP_001188258.1|refseq:NP_078883.2|refseq:XP_006716316.1|refseq:XP_016869324.1 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:orhf/0MSEUfycwPk+D9BN8A6Ld89606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O43143 uniprotkb:C9JA69 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 intact:EBI-10967491|ensembl:ENSP00000385317 psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:c9ja69_human(display_long)|uniprotkb:BBX(gene name)|psi-mi:BBX(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-20723936|imex:IM-26492-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) ensembl:ENSG00000114439(gene)|ensembl:ENST00000402543(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR019102|interpro:IPR036910 - - - figure legend:f6 st2|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rogid:6jAszkpZ9e+JSFXuwl92t0K4tTQ9606 rigid:cy0OF8tokASkRP3DBcv4hA4uCK0 false green fluorescent protein tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q12874 uniprotkb:O43143 intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-20724040|imex:IM-26492-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:f7h|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:fNjNguUOXqApr46rOAEpTs2geqY9606 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rigid:rHljYshu9AIaJ/hI5W+1qhFcVP0 false - green fluorescent protein tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q96RS6-1 uniprotkb:O43143 intact:EBI-20724008|ensembl:ENSP00000239690 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:q96rs6-1(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-L(isoform synonym) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-20724016|imex:IM-26492-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|intact:EBI-2512429(isoform-parent) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:f5a|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rigid:a6w16O8Om2/dm0gQmIpH8Xm/isA false green fluorescent protein tag:c-c myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96RS6-1 uniprotkb:O43143 intact:EBI-20724008|ensembl:ENSP00000239690 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:q96rs6-1(display_long)|uniprotkb:NUDCD1(gene name)|psi-mi:NUDCD1(display_short)|uniprotkb:CML66(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 66(gene name synonym)|uniprotkb:Tumor antigen CML66(gene name synonym)|uniprotkb:CML66-L(isoform synonym) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Asselin-Mullen et al. (2017) pubmed:29021621|imex:IM-26492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-20724024|imex:IM-26492-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120526(gene)|ensembl:ENST00000239690(transcript)|intact:EBI-2512429(isoform-parent) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:f5b|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2017/11/30 2018/08/22 rogid:VfINO8Qk3jMFWzVI+0Bd6xk90/E9606 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rigid:a6w16O8Om2/dm0gQmIpH8Xm/isA false green fluorescent protein tag:c-c myc tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)