#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6IQ23 uniprotkb:Q9UKV8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9C0C2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2104458|uniprotkb:Q6PJ35|uniprotkb:Q6ZV74|uniprotkb:A7E2F8|intact:EBI-28975617|ensembl:ENSP00000350990|ensembl:ENSP00000437271 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tb182_human(display_long)|uniprotkb:TNKS1BP1(gene name)|psi-mi:TNKS1BP1(display_short)|uniprotkb:KIAA1741(gene name synonym)|uniprotkb:TAB182(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:XP_006718788.1|ensembl:ENSP00000350990|ensembl:ENSP00000437271|refseq:NP_203754.2|ensembl:ENSG00000149115(gene)|ensembl:ENST00000358252(transcript)|ensembl:ENST00000532437(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR032764|interpro:IPR040006|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pOIaK7wn7iYvUHbSA0kUZlIgtgw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P35249 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P17612 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UQ80 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H201 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-7221344|intact:MINT-1199053|uniprotkb:Q9BVN6|uniprotkb:A8K6J3|uniprotkb:A8KAB2|uniprotkb:Q9NWK2|intact:EBI-28967454|ensembl:ENSP00000268933 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:epn3_human(display_long)|uniprotkb:EPN3(gene name)|psi-mi:EPN3(display_short)|uniprotkb:EPS-15-interacting protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000268933|ensembl:ENST00000510045|ensembl:ENSP00000421933|refseq:NP_060427.2|ensembl:ENSG00000049283(gene)|ensembl:ENST00000268933(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990175"(EH domain binding)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR027318 - - comment:mint|comment:homomint figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:jUdhw8lZdwADbilLc4JcpyGeKRQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00499-10 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-7689134|intact:MINT-258409|ensembl:ENSP00000365281 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o00499-10(display_long)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-719094(isoform-parent)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000376113(transcript) - - comment:mint figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:yCLeWtbqSmKzYGsrJovGsWn4yBQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75695 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-7996807|uniprotkb:Q9NU67|uniprotkb:Q86XJ7|intact:MINT-5003911|ensembl:ENSP00000218340 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:xrp2_human(display_long)|uniprotkb:RP2(gene name)|psi-mi:RP2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_008846.2|dip:DIP-29024N|ensembl:ENSG00000102218(gene)|ensembl:ENST00000218340(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR006599(CARP motif)|interpro:IPR012945(Tubulin binding cofactor C)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR036223|interpro:IPR036850|interpro:IPR039093|mint:O75695|rcsb pdb:2BX6|rcsb pdb:3BH6|rcsb pdb:3BH7|reactome:R-HSA-5624138 - - comment:mint|function:Stimulates the GTPase activity of tubulin, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor for ARL3|function:"Defects in RP2 are the cause of retinitis pigmentosa type 2 (RP2) [MIM:312600]; also known as X-linked retinitis pigmentosa 2 (XLRP-2). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well" figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:34VzWqa5cV0XAIxDOCDGzd+1VPk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q16651 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-7246681|uniprotkb:B4DWP2|intact:MINT-5000236|uniprotkb:Q9UCA3|ensembl:ENSP00000319730 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:prss8_human(display_long)|uniprotkb:Channel-activating protease 1(gene name synonym)|uniprotkb:PRSS8(gene name)|psi-mi:PRSS8(display_short)|uniprotkb:Serine protease 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002764.1|ensembl:ENSG00000052344(gene)|ensembl:ENST00000317508(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|go:"GO:0017080"(sodium channel regulator activity)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:3DFJ|rcsb pdb:3DFL|rcsb pdb:3E0N|rcsb pdb:3E0P|rcsb pdb:3E16|rcsb pdb:3E1X|rcsb pdb:3FVF|rcsb pdb:3GYL|rcsb pdb:3GYM|reactome:R-HSA-6809371 - - comment:mint|comment:homomint|function:Possesses a trypsin-like cleavage specificity figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:QnM4TQgJm3CP4GkJAvtsEfJ62uk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15637-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-7176142|ensembl:ENSP00000334414|intact:MINT-1582461 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q15637-2(display_long)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Bone(isoform synonym)|uniprotkb:SF1-Bo(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000168066(gene)|ensembl:ENST00000334944(transcript)|intact:EBI-744603(isoform-parent)|uniprotkb:Q15637-2(isoform-parent) - - comment:mint figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ZUDU+A9OMn7Tf2WaMP+L68EoFTE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q01105-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-7481343|intact:MINT-2610947|ensembl:ENSP00000318012 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q01105-2(display_long)|uniprotkb:SET(gene name)|psi-mi:SET(display_short)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:TAF-I beta(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1053182(isoform-parent)|ensembl:ENSG00000119335(gene)|ensembl:ENST00000322030(transcript)|uniprotkb:Q01105-2(isoform-parent) - - isoform-comment:"Variant in position: 4:P->Q (in dbSNP:rs1141138). Contains a N6-acetyllysine at position 11. Contains a phosphoserine at position 15. Contains a phosphoserine at position 24."|comment:mint figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:L1O5tYLNTg1XsR0kowMDRZAItTU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6ZU35 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11319666|uniprotkb:Q9NTE2|uniprotkb:Q9ULK9|uniprotkb:Q9NTP8|ensembl:ENSP00000264229|ensembl:ENSP00000423366|ensembl:ENSP00000507165 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cracd_human(display_long)|uniprotkb:CRACD(gene name)|psi-mi:CRACD(display_short)|uniprotkb:CRAD(gene name synonym)|uniprotkb:Cancer-related regulator of actin dynamics(gene name synonym)|uniprotkb:KIAA1211(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_065773.1|refseq:XP_005265809.1|refseq:XP_011532699.1|ensembl:ENSG00000109265(gene)|ensembl:ENST00000264229(transcript)|ensembl:ENST00000504228(transcript)|ensembl:ENST00000682029(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR028030 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:L/12y6fRwlL887BYRkdEjhnDRFw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14642 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-8670520|ensembl:ENSP00000357583|uniprotkb:Q14640|intact:UNK-5392019|uniprotkb:Q5JSF1|uniprotkb:D3DXI3 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:i5p1_human(display_long)|uniprotkb:43 kDa inositol polyphosphate 5-phosphatase(gene name synonym)|uniprotkb:5PTASE(gene name synonym)|uniprotkb:Type I inositol 1,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:INPP5A(gene name)|psi-mi:INPP5A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000068383(gene)|ensembl:ENST00000368594(transcript)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0042731"(PH domain binding)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048016"(inositol phosphate-mediated signaling)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0052659"(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|interpro:IPR039737|reactome:R-HSA-1855183|refseq:NP_001307971.1|refseq:NP_005530.3 - - comment:mint|function:"Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction" figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:WggXPOR+hZ/sOcfwveU1ErIdLS09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P61978-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-7060731|ensembl:ENSP00000365439|ensembl:ENSP00000365458|uniprotkb:Q07244-2|intact:MINT-225449 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p61978-2(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000165119(gene)|ensembl:ENST00000376263(transcript)|ensembl:ENST00000376281(transcript)|intact:EBI-304185(isoform-parent)|uniprotkb:P61978-2(isoform-parent) - - comment:mint figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:FX/iS2YfOhD0ntY2oqpOUetACqg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P35052 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-8307554|ensembl:ENSP00000264039|intact:UNK-5376584|uniprotkb:Q53QM4|intact:UNK-5431308|uniprotkb:B3KTD1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gpc1_human(display_long)|uniprotkb:GPC1(gene name)|psi-mi:GPC1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000063660(gene)|ensembl:ENST00000264039(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0016477"(cell migration)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032288"(myelin assembly)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043236"(laminin binding)|go:"GO:0045121"(membrane raft)|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-376176|reactome:R-HSA-4420332|reactome:R-HSA-975634|go:"GO:0045202"(synapse)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1905475"(regulation of protein localization to membrane)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR001863(Glypican)|interpro:IPR015502(Glypican1)|interpro:IPR019803|mint:P35052|rcsb pdb:4ACR|rcsb pdb:4AD7|rcsb pdb:4BWE|rcsb pdb:4YWT|reactome:R-HSA-1971475|reactome:R-HSA-2022928|refseq:NP_002072.2 - - function:Cell surface proteoglycan that bears heparan sulfate|comment:mint figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ycuKz8cHA1TlfV2XkBz+onEEwyw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P21333-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-9641086|ensembl:ENSP00000353467 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p21333-2(display_long)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-350432(isoform-parent)|ensembl:ENSG00000196924(gene)|ensembl:ENST00000360319(transcript)|uniprotkb:P21333-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:r3XEZc6gmq37vSWBuSgyVvIf7Sc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NXR1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-7191649|intact:MINT-4944181|ensembl:ENSP00000379642|ensembl:ENSP00000379643|ensembl:ENSP00000488050|ensembl:ENSP00000488199|ensembl:ENSP00000501936|ensembl:ENSP00000502160|ensembl:ENSP00000502354|ensembl:ENSP00000502635 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9nxr1-2(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short)|uniprotkb:NUDE(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-941227(isoform-parent)|uniprotkb:Q9NXR1-2(isoform-parent)|ensembl:ENSG00000072864(gene)|ensembl:ENSG00000275911(gene)|ensembl:ENST00000396354(transcript)|ensembl:ENST00000396355(transcript)|ensembl:ENST00000631844(transcript)|ensembl:ENST00000631923(transcript)|ensembl:ENST00000674554(transcript)|ensembl:ENST00000674888(transcript)|ensembl:ENST00000675926(transcript)|ensembl:ENST00000675951(transcript) - - comment:mint|comment:homomint figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:H769EmQerGWsy6Zud3BBzkAuQw49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P15311 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96B26 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:y/cReHiPMubzNruyETohBjbRick9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15024 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96J88-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399424 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96j88-2(display_long)|uniprotkb:EPSTI1(gene name)|psi-mi:EPSTI1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 uniprotkb:Q96J88(isoform-parent)|uniprotkb:Q96J88-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:gaXcGoqeO/+B9tyDck0PMotMhkY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H6S3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3940939|uniprotkb:Q53GM8|uniprotkb:Q9H6K9|uniprotkb:B3KSX1|uniprotkb:Q96K06|uniprotkb:Q8WYW7|ensembl:ENSP00000320828|ensembl:ENSP00000435585|ensembl:ENSP00000436035|uniprotkb:B7ZKL3 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:es8l2_human(display_long)|uniprotkb:EPS8L2(gene name)|psi-mi:EPS8L2(display_short)|uniprotkb:EPS8R2(gene name synonym)|uniprotkb:Epidermal growth factor receptor pathway substrate 8-related protein 2(gene name synonym)|uniprotkb:PP13181(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000177106(gene)|ensembl:ENST00000318562(transcript)|ensembl:ENST00000530636(transcript)|ensembl:ENST00000533256(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0031982"(vesicle)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045296"(cadherin binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|mint:Q9H6S3|rcsb pdb:1WWU|rcsb pdb:1WXB|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_073609.2|refseq:XP_016873619.1|refseq:XP_016873620.1|refseq:XP_016873621.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:fm46f0tF2y2QGPLD7dk77JUHMXA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BS26 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-541644|uniprotkb:O60319|uniprotkb:Q5VWZ7|uniprotkb:Q6UW14|uniprotkb:Q8WX67|intact:EBI-1054855|uniprotkb:Q4VXC1|ensembl:ENSP00000262455 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:erp44_human(display_long)|uniprotkb:ERP44(gene name)|psi-mi:ERP44(display_short)|uniprotkb:UNQ532/PRO1075(orf name)|uniprotkb:TXNDC4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:KIAA0573(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000023318(gene)|ensembl:ENST00000262455(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009986"(cell surface)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|mint:Q9BS26|rcsb pdb:2R2J|rcsb pdb:5GU6|rcsb pdb:5GU7|rcsb pdb:5HQP|rcsb pdb:5XWM|reactome:R-HSA-6798695|go:"GO:0009100"(glycoprotein metabolic process)|refseq:NP_055866.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:TpwaFRifveb03iRPS2pEZve1kLA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O94905 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75477 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75616 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-6393536|ensembl:ENSP00000254928|uniprotkb:B3KN21|uniprotkb:C9JEC6|uniprotkb:O75617|uniprotkb:Q8WUY4|uniprotkb:Q96LE2|uniprotkb:Q96TC0 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eral1_human(display_long)|uniprotkb:ERAL1(gene name)|psi-mi:ERAL1(display_short)|uniprotkb:HERA(gene name synonym)|uniprotkb:Conserved ERA-like GTPase(gene name synonym)|uniprotkb:ERA-W(gene name synonym)|uniprotkb:ERA-like protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000132591(gene)|ensembl:ENST00000254928(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005662(GTP-binding protein Era)|interpro:IPR006073(GTP1/OBG)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR027417|interpro:IPR030388|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_005693.1|refseq:NP_001304914.1|refseq:NP_001304915.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:2usCrRc4/GbXG5Ft8GY61w+rGds9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P42566 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14677-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10983245|ensembl:ENSP00000429824 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q14677-3(display_long)|uniprotkb:CLINT1(gene name)|psi-mi:CLINT1(display_short)|uniprotkb:Clathrin-interacting protein localized in the trans-Golgi region(gene name synonym)|uniprotkb:ENTH(gene name synonym)|uniprotkb:EPN4(gene name synonym)|uniprotkb:EPNR(gene name synonym)|uniprotkb:Enthoprotin(gene name synonym)|uniprotkb:Epsin-4(gene name synonym)|uniprotkb:Epsin-related protein(gene name synonym)|uniprotkb:KIAA0171(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1171113(isoform-parent)|ensembl:ENSG00000113282(gene)|ensembl:ENST00000523908(transcript) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:of9/yDWoY9Vg+oiSMmZMV58QvWI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y6I3-1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399445|ensembl:ENSP00000406209 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9y6i3-1(display_long)|uniprotkb:EH domain-binding mitotic phosphoprotein(gene name synonym)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)|uniprotkb:EPN1(gene name)|psi-mi:EPN1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000063245(gene)|ensembl:ENST00000411543(transcript)|intact:EBI-713198(isoform-parent)|uniprotkb:Q9Y6I3-1(isoform-parent) - - isoform-comment:"Ref.1 (AAD38326) sequence differs from that shown due to frameshift." figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:nZQJEOXl3LvY93rC677JL117YCc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UNN8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-719705|uniprotkb:Q14218|uniprotkb:Q6IB56|uniprotkb:Q96CB3|uniprotkb:Q9ULX1|uniprotkb:B2RC04|ensembl:ENSP00000216968 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:epcr_human(display_long)|uniprotkb:Endothelial cell protein C receptor(gene name synonym)|uniprotkb:Activated protein C receptor(gene name synonym)|uniprotkb:PROCR(gene name)|psi-mi:PROCR(display_short)|uniprotkb:EPCR(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006395.2|ensembl:ENSG00000101000(gene)|ensembl:ENST00000216968(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR015669(Endothelial protein C receptor)|interpro:IPR037055|rcsb pdb:1L8J|rcsb pdb:1LQV|rcsb pdb:3JTC|rcsb pdb:4V3D|rcsb pdb:4V3E|rcsb pdb:6SNY|reactome:R-HSA-140875|reactome:R-HSA-202733|dip:DIP-48671N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:E5YufhPX46Id1xm4YN03ZG+UYPU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P16422 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1171184|uniprotkb:P18180|uniprotkb:Q96C47|uniprotkb:Q6FG26|uniprotkb:Q6FG49|uniprotkb:Q9UCD0|ensembl:ENSP00000263735 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:epcam_human(display_long)|uniprotkb:EPCAM(gene name)|psi-mi:EPCAM(display_short)|uniprotkb:GA733-2(gene name synonym)|uniprotkb:M1S2(gene name synonym)|uniprotkb:TROP1(gene name synonym)|uniprotkb:Major gastrointestinal tumor-associated protein GA733-2(gene name synonym)|uniprotkb:Epithelial cell surface antigen(gene name synonym)|uniprotkb:Epithelial glycoprotein(gene name synonym)|uniprotkb:Adenocarcinoma-associated antigen(gene name synonym)|uniprotkb:KSA(gene name synonym)|uniprotkb:KS 1/4 antigen(gene name synonym)|uniprotkb:Cell surface glycoprotein Trop-1(gene name synonym)|uniprotkb:M4S1(gene name synonym)|uniprotkb:MIC18(gene name synonym)|uniprotkb:TACSTD1(gene name synonym)|uniprotkb:Tumor-associated calcium signal transducer 1(gene name synonym)|uniprotkb:Epithelial glycoprotein 314(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002345.2|ensembl:ENSG00000119888(gene)|ensembl:ENST00000263735(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR041630|interpro:IPR043406|mint:P16422|rcsb pdb:4MZV|rcsb pdb:6I07|reactome:R-HSA-202733|go:"GO:0009986"(cell surface) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:mzYNoxHCDJuzMM5HkW5FIOaxm1w9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UBC2-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10980349|ensembl:ENSP00000393313 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9ubc2-2(display_long)|uniprotkb:EPS15L1(gene name)|psi-mi:EPS15L1(display_short)|uniprotkb:EPS15R(gene name synonym)|uniprotkb:Eps15-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000127527(gene)|ensembl:ENST00000455140(transcript)|intact:EBI-2556746(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:BYED7lYYVMpzc7D7TghXnbLa7Qs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P14625 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P54851 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-9083553|uniprotkb:B2R7V6|uniprotkb:D3DUF8|ensembl:ENSP00000352540|ensembl:ENSP00000445712 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:emp2_human(display_long)|uniprotkb:EMP2(gene name)|psi-mi:EMP2(display_short)|uniprotkb:XMP(gene name synonym)|uniprotkb:Protein XMP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001415.1|refseq:XP_006720927.1|ensembl:ENSG00000213853(gene)|ensembl:ENST00000359543(transcript)|ensembl:ENST00000536829(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003093"(regulation of glomerular filtration)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0008219"(cell death)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032060"(bleb assembly)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001212"(regulation of vasculogenesis)|interpro:IPR003933(Epithelial membrane protein EMP-2)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR004032(PMP-22/EMP/MP20) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:EUVI+CwVw3JJidad+/TkmOBKEeo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P50402 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9HC35 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-717876|uniprotkb:Q3SWW0|uniprotkb:Q53R29|uniprotkb:Q53TW8|uniprotkb:Q6PJ45|uniprotkb:Q9NV40|uniprotkb:B2RTW7|uniprotkb:B2RBK3|uniprotkb:A6H8Y6|uniprotkb:B5MCW9|intact:EBI-28969987|ensembl:ENSP00000320663 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:emal4_human(display_long)|uniprotkb:Restrictedly overexpressed proliferation-associated protein(gene name synonym)|uniprotkb:Ropp 120(gene name synonym)|uniprotkb:EML4(gene name)|psi-mi:EML4(display_short)|uniprotkb:C2orf2(gene name synonym)|uniprotkb:EMAPL4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_061936.2|ensembl:ENSP00000320663|ensembl:ENST00000402711|ensembl:ENSP00000385059|refseq:NP_001138548.1|ensembl:ENSG00000143924(gene)|ensembl:ENST00000318522(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR001680(WD40 repeat)|interpro:IPR005108(HELP)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4CGC|reactome:R-HSA-9648025 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Uil30Xzo4QqT/8hfUP7TJbuCG3o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15717 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q7L2H7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-353901|intact:EBI-4289539|intact:EBI-715219|uniprotkb:Q2F836|uniprotkb:Q53HL6|uniprotkb:Q9BXW1|uniprotkb:O60735|uniprotkb:A8K7X4|intact:EBI-2559366|ensembl:ENSP00000436049|intact:EBI-373200|uniprotkb:B4E2Q4 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eif3m_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)|uniprotkb:HFLB5(gene name synonym)|uniprotkb:PCID1(gene name synonym)|uniprotkb:PCI domain-containing protein 1(gene name synonym)|uniprotkb:Fetal lung protein B5(gene name synonym)|uniprotkb:GA17(orf name)|uniprotkb:PNAS-125(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006351.2|refseq:NP_001294858.1|ensembl:ENSG00000149100(gene)|ensembl:ENST00000531120(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027528|interpro:IPR036390|interpro:IPR040750|mint:Q7L2H7|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31256N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:siTfTDezqWL90pw6xG3xUKfY9n49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75822 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-366647|uniprotkb:Q9BUD2|uniprotkb:Q9H8Q2|uniprotkb:Q9UI65|ensembl:ENSP00000261868|uniprotkb:B4DUI3|uniprotkb:F5H425 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eif3j_human(display_long)|uniprotkb:EIF3J(gene name)|psi-mi:EIF3J(display_short)|uniprotkb:PRO0391(orf name)|uniprotkb:EIF3S1(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 1(gene name synonym)|uniprotkb:eIF-3-alpha(gene name synonym)|uniprotkb:eIF3 p35(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001271264.1|refseq:NP_001271265.1|refseq:NP_003749.2|ensembl:ENSG00000104131(gene)|ensembl:ENST00000261868(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR013906(Translation initiation factor eIF3 subunit)|interpro:IPR023194|mint:O75822|rcsb pdb:2KRB|rcsb pdb:3BPJ|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31117N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:dJ+uqlLn3RH30Rw3COnJ+/nkk+I9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13347 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-354047|intact:EBI-11759480|ensembl:ENSP00000504034|ensembl:ENSP00000504061|ensembl:ENSP00000502867|ensembl:ENSP00000503348|ensembl:ENSP00000503539 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eif3i_human(display_long)|uniprotkb:EIF3I(gene name)|psi-mi:EIF3I(display_short)|uniprotkb:TRIP1(gene name synonym)|uniprotkb:EIF3S2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003748.1|ensembl:ENST00000676801(transcript)|ensembl:ENST00000677202(transcript)|ensembl:ENST00000677701(transcript)|ensembl:ENST00000677711(transcript)|ensembl:ENST00000677760(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|ensembl:ENSG00000084623(gene)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q13347|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31116N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:fogC6nSNmIynV2ziHZboT9laA3M9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O15372 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-709735|ensembl:ENSP00000429931 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75821 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O15371 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P55884-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399439 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p55884-2(display_long)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-366696(isoform-parent)|uniprotkb:P55884-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:fJffxmlQIIj2hDRfKh2o+i6vqbs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14152 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H4M9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-490691|uniprotkb:O14611|uniprotkb:Q2M3Q4|uniprotkb:Q9UNR3|ensembl:ENSP00000320516|ensembl:ENSP00000352354 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ehd1_human(display_long)|uniprotkb:Testilin(gene name synonym)|uniprotkb:CDABP0131(orf name)|uniprotkb:EHD1(gene name)|psi-mi:EHD1(display_short)|uniprotkb:PAST(gene name synonym)|uniprotkb:PAST1(gene name synonym)|uniprotkb:PAST homolog 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_006786.2|refseq:XP_011543041.1|refseq:NP_001269373.1|refseq:NP_001269374.1|ensembl:ENSG00000110047(gene)|ensembl:ENST00000320631(transcript)|ensembl:ENST00000359393(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H4M9|rcsb pdb:2JQ6|rcsb pdb:2KFF|rcsb pdb:2KFG|rcsb pdb:2KFH|rcsb pdb:2KSP|reactome:R-HSA-983231 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:txUfRMtv6SbBqKKJ1DVM6K/pj2Y9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P49411 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P13639 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P26641 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P29692 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358607|uniprotkb:Q969J1|uniprotkb:D3DWK3|intact:EBI-748782|uniprotkb:Q96I38|ensembl:ENSP00000317399|ensembl:ENSP00000378551|ensembl:ENSP00000388261|ensembl:ENSP00000433412|ensembl:ENSP00000433611|ensembl:ENSP00000434448|ensembl:ENSP00000434872|ensembl:ENSP00000436542|ensembl:ENSP00000436933|ensembl:ENSP00000478340|ensembl:ENSP00000479653|ensembl:ENSP00000483527|ensembl:ENSP00000487680|intact:EBI-11048966|uniprotkb:Q4VBZ6|uniprotkb:B4DDU4|uniprotkb:E9PBQ9 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ef1d_human(display_long)|uniprotkb:EEF1D(gene name)|psi-mi:EEF1D(display_short)|uniprotkb:EF1D(gene name synonym)|uniprotkb:Antigen NY-CO-4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001123528.1|refseq:NP_001123527.1|refseq:NP_001123529.1|refseq:NP_001951.2|refseq:XP_011515207.1|refseq:XP_011515208.1|ensembl:ENST00000419152(transcript)|ensembl:ENST00000529272(transcript)|ensembl:ENST00000530191(transcript)|ensembl:ENST00000530445(transcript)|ensembl:ENST00000531218(transcript)|ensembl:ENST00000533494(transcript)|ensembl:ENST00000534380(transcript)|ensembl:ENST00000614575(transcript)|ensembl:ENST00000615067(transcript)|ensembl:ENST00000615698(transcript)|ensembl:ENST00000632587(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0009299"(mRNA transcription)|go:"GO:0010941"(regulation of cell death)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|mint:P29692|rcsb pdb:2MVM|rcsb pdb:2MVN|rcsb pdb:2N51|rcsb pdb:5JPO|reactome:R-HSA-156842|ensembl:ENSG00000104529(gene)|ensembl:ENSG00000273594(gene)|ensembl:ENST00000317198(transcript)|ensembl:ENST00000395119(transcript)|refseq:NP_001304672.1|refseq:NP_001182132.1|refseq:NP_001276879.1|refseq:XP_006716585.1|refseq:XP_006716586.1|refseq:XP_006716587.1|refseq:XP_006716588.1|refseq:XP_005250880.1|refseq:NP_001317575.1|refseq:XP_016868659.1|refseq:NP_001123525.2|refseq:NP_115754.3 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:9Mzpfofeg2W/GQ/JfjFxcCFJnKg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P68104 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6P2E9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96F86 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P55084 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P40939 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:E7EVA0 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11140077|ensembl:ENSP00000407602 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:e7eva0_human(display_long)|uniprotkb:MAP4(gene name)|psi-mi:MAP4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000047849(gene)|ensembl:ENST00000426837(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|go:"GO:0005829"(cytosol) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:DGRmA1OSdcpvXPEzDsN2cun9tuo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9HCM4-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1907289|ensembl:ENSP00000329687|ensembl:ENSP00000393722 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9hcm4-2(display_long)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1047162(isoform-parent)|ensembl:ENSG00000115109(gene)|ensembl:ENST00000331393(transcript)|ensembl:ENST00000443124(transcript)|uniprotkb:Q9HCM4-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:yPc+xqaXHhnLbpjOcRlYrhPCLE89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43491 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1052044|uniprotkb:Q5T4F0|uniprotkb:B4DHI8|uniprotkb:Q68DV2|uniprotkb:E9PPD9|ensembl:ENSP00000338481|ensembl:ENSP00000357110 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:e41l2_human(display_long)|uniprotkb:Generally expressed protein 4.1(gene name synonym)|uniprotkb:EPB41L2(gene name)|psi-mi:EPB41L2(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001422.1|refseq:NP_001129026.1|refseq:NP_001129027.1|refseq:NP_001239589.1|refseq:XP_011533832.1|refseq:XP_011533836.1|ensembl:ENSG00000079819(gene)|ensembl:ENST00000337057(transcript)|ensembl:ENST00000368128(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0008091"(spectrin)|go:"GO:0030054"(cell junction)|go:"GO:0030507"(spectrin binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042731"(PH domain binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030546|interpro:IPR035963|mint:O43491|reactome:R-HSA-6794361|refseq:XP_016865844.1|refseq:XP_016865848.1|refseq:XP_016865849.1|refseq:XP_016865850.1|refseq:XP_016865851.1|dip:DIP-17034N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:QvhY6g+bBqTBR8oHl/php27Wb7Y9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H4G0-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11027417|ensembl:ENSP00000202028|ensembl:ENSP00000399214 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9h4g0-2(display_long)|uniprotkb:EPB41L1(gene name)|psi-mi:EPB41L1(display_short)|uniprotkb:KIAA0338(gene name synonym)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000088367(gene)|ensembl:ENST00000202028(transcript)|ensembl:ENST00000441639(transcript)|intact:EBI-465536(isoform-parent) - - isoform-comment:Contains a N-acetylmethionine at position 1. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:9VwcZjLyXMIhATWQ7p65pS5QZY89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14126 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2556545|uniprotkb:Q4KKU6|ensembl:ENSP00000261590 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dsg2_human(display_long)|uniprotkb:CDHF5(gene name synonym)|uniprotkb:HDGC(gene name synonym)|uniprotkb:Cadherin family member 5(gene name synonym)|uniprotkb:DSG2(gene name)|psi-mi:DSG2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001934.2|reactome:R-HSA-9013423|ensembl:ENSG00000046604(gene)|ensembl:ENST00000261590(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003165"(Purkinje myocyte development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|rcsb pdb:2YQG|rcsb pdb:5ERD|rcsb pdb:5J5J|rcsb pdb:6QNT|rcsb pdb:6QNU|rcsb pdb:6SIT|rcsb pdb:7A7D|rcsb pdb:7AGF|rcsb pdb:7AGG|reactome:R-HSA-351906|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9013404|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|reactome:R-HSA-9013408|dip:DIP-46250N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:LCSf84WRgh5lTrze5IEzFaBeuEc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y295 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-719554|uniprotkb:Q6FGP8|uniprotkb:Q8WW69|uniprotkb:Q9UGF2|uniprotkb:B2RDS8|ensembl:ENSP00000329715 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:drg1_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 3(gene name synonym)|uniprotkb:DRG1(gene name)|psi-mi:DRG1(display_short)|uniprotkb:NEDD3(gene name synonym)|uniprotkb:Translation factor GTPase DRG1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004138.1|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|rcsb pdb:2EKI|go:"GO:0005844"(polysome)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|ensembl:ENSG00000185721(gene)|ensembl:ENST00000331457(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:gVbgvaeulEwp7MdnP+qRgZ/aawA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q16643 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|ensembl:ENSP00000308532|intact:EBI-4404710|uniprotkb:A8MV58 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758(gene)|ensembl:ENST00000309007(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0042641"(actomyosin)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q16643|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|go:"GO:0032507"(maintenance of protein location in cell)|refseq:XP_016864629.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P27487 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2871277|uniprotkb:Q53TN1|ensembl:ENSP00000353731 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dpp4_human(display_long)|uniprotkb:DPP4(gene name)|psi-mi:DPP4(display_short)|uniprotkb:ADCP2(gene name synonym)|uniprotkb:CD26(gene name synonym)|uniprotkb:ADABP(gene name synonym)|uniprotkb:Adenosine deaminase complexing protein 2(gene name synonym)|uniprotkb:Dipeptidyl peptidase IV(gene name synonym)|uniprotkb:T-cell activation antigen CD26(gene name synonym)|uniprotkb:TP103(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001926.2|dip:DIP-351N|ensembl:ENSG00000197635(gene)|ensembl:ENST00000360534(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002020"(protease binding)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008239"(dipeptidyl-peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010716"(negative regulation of extracellular matrix disassembly)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0033632"(regulation of cell-cell adhesion mediated by integrin)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002469(Peptidase S9B, dipeptidylpeptidase IV N-terminal)|interpro:IPR002471(Peptidase S9, serine active site)|interpro:IPR029058|mint:P27487|rcsb pdb:1J2E|rcsb pdb:1N1M|rcsb pdb:1NU6|rcsb pdb:1NU8|rcsb pdb:1PFQ|rcsb pdb:1R9M|rcsb pdb:1R9N|rcsb pdb:1RWQ|rcsb pdb:1TK3|rcsb pdb:1TKR|rcsb pdb:1U8E|rcsb pdb:1W1I|rcsb pdb:1WCY|rcsb pdb:1X70|rcsb pdb:2AJL|rcsb pdb:2BGN|rcsb pdb:2BGR|rcsb pdb:2BUB|rcsb pdb:2FJP|rcsb pdb:2G5P|rcsb pdb:2G5T|rcsb pdb:2G63|rcsb pdb:2HHA|rcsb pdb:2I03|rcsb pdb:2I78|rcsb pdb:2IIV|rcsb pdb:2JID|rcsb pdb:2OAG|rcsb pdb:2OGZ|rcsb pdb:2OLE|rcsb pdb:2ONC|rcsb pdb:2OPH|rcsb pdb:2OQI|rcsb pdb:2OQV|rcsb pdb:2P8S|rcsb pdb:2QJR|rcsb pdb:2QKY|rcsb pdb:2QOE|rcsb pdb:2QT9|rcsb pdb:2IIT|rcsb pdb:2QTB|rcsb pdb:2RGU|rcsb pdb:2RIP|rcsb pdb:3BJM|rcsb pdb:3C43|rcsb pdb:3C45|rcsb pdb:3CCB|rcsb pdb:3CCC|rcsb pdb:3D4L|rcsb pdb:3EIO|rcsb pdb:3F8S|rcsb pdb:3G0B|rcsb pdb:3G0C|rcsb pdb:3G0D|rcsb pdb:3G0G|rcsb pdb:3H0C|rcsb pdb:3HAB|rcsb pdb:3HAC|rcsb pdb:3KWF|rcsb pdb:3KWJ|rcsb pdb:3NOX|rcsb pdb:3O95|rcsb pdb:3O9V|rcsb pdb:3OC0|rcsb pdb:3OPM|rcsb pdb:3Q0T|rcsb pdb:3Q8W|rcsb pdb:3SWW|rcsb pdb:3SX4|rcsb pdb:3VJK|rcsb pdb:3VJL|rcsb pdb:3VJM|rcsb pdb:3W2T|rcsb pdb:3WQH|rcsb pdb:4A5S|rcsb pdb:4DSA|rcsb pdb:4DSZ|rcsb pdb:4DTC|rcsb pdb:4G1F|rcsb pdb:4J3J|rcsb pdb:4JH0|rcsb pdb:4KR0|rcsb pdb:4L72|rcsb pdb:4LKO|rcsb pdb:4N8D|rcsb pdb:4N8E|rcsb pdb:4PNZ|rcsb pdb:4PV7|rcsb pdb:4QZV|rcsb pdb:5I7U|rcsb pdb:5ISM|rcsb pdb:5J3J|rcsb pdb:5KBY|rcsb pdb:5T4B|rcsb pdb:5T4E|rcsb pdb:5T4F|rcsb pdb:5T4H|rcsb pdb:5Y7H|rcsb pdb:5Y7J|rcsb pdb:5Y7K|rcsb pdb:5ZID|rcsb pdb:6B1E|rcsb pdb:6B1O|reactome:R-HSA-381771|reactome:R-HSA-400511|rcsb pdb:3QBJ - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:D8cgqdBbAfEQk+G2GhDuJvrkBcE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6XZF7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2483419|ensembl:ENSP00000315659|uniprotkb:Q8IVY3|uniprotkb:Q9Y2L3 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dnmbp_human(display_long)|uniprotkb:DNMBP(gene name)|psi-mi:DNMBP(display_short)|uniprotkb:KIAA1010(gene name synonym)|uniprotkb:Scaffold protein Tuba(gene name synonym)|uniprotkb:ARHGEF36(gene name synonym)|uniprotkb:TUBA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000107554(gene)|ensembl:ENST00000324109(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007568"(aging)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045202"(synapse)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0098793"(presynapse)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035469|interpro:IPR035817|interpro:IPR035818|interpro:IPR035819|interpro:IPR035820|interpro:IPR035899|interpro:IPR036028|mint:Q6XZF7|rcsb pdb:1UG1|rcsb pdb:1UHC|rcsb pdb:4CC2|rcsb pdb:4CC3|rcsb pdb:4CC4|rcsb pdb:4CC7|rcsb pdb:4GLM|reactome:R-HSA-9013148|refseq:XP_011537861.1|refseq:NP_056036.1|refseq:NP_001305255.1|refseq:NP_001305256.1|dip:DIP-53822N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Pnps+8tUGF35nxMUaPgDr5hzRzc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P25686-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399430|ensembl:ENSP00000375936 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p25686-2(display_long)|uniprotkb:Heat shock 40 kDa protein 3(gene name synonym)|uniprotkb:Heat shock protein J1(gene name synonym)|uniprotkb:DNAJB2a(isoform synonym)|uniprotkb:HSJ1a(isoform synonym)|uniprotkb:DNAJB2(gene name)|psi-mi:DNAJB2(display_short)|uniprotkb:HSJ1(gene name synonym)|uniprotkb:HSPF3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000135924(gene)|ensembl:ENST00000392086(transcript)|intact:EBI-6166532(isoform-parent)|uniprotkb:P25686-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:f4XUkjoxoA34vJe5Zhq4ouAZ5TM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P25685 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60884 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P31689 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q12959-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357500|ensembl:ENSP00000345731|intact:EBI-7915005|intact:EBI-7915073|intact:EBI-7915143|intact:EBI-7915210|intact:EBI-7915398|intact:EBI-7914769|intact:MINT-107714|intact:EBI-7914861|intact:EBI-7915314|intact:EBI-7914914 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q12959-2(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000075711(gene)|ensembl:ENST00000346964(transcript)|intact:EBI-357481(dlg1_human)|uniprotkb:Q12959-2(isoform-parent) - - isoform-comment:Contains a phosphoserine at position 709. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:YETcLwmae16VPu6Mc9feJ1TmOPU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NXW2-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399240 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9nxw2-2(display_long)|uniprotkb:DNAJB12(gene name)|psi-mi:DNAJB12(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 uniprotkb:Q9NXW2(isoform-parent)|uniprotkb:Q9NXW2-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:9KRhdvw/VdKQmJ7HGZWNIj61n049606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UBS4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UPY3-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399295|ensembl:ENSP00000444719 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9upy3-2(display_long)|uniprotkb:Helicase with RNase motif(gene name synonym)|uniprotkb:DICER1(gene name)|psi-mi:DICER1(display_short)|uniprotkb:DICER(gene name synonym)|uniprotkb:HERNA(gene name synonym)|uniprotkb:KIAA0928(gene name synonym)|uniprotkb:t-Dicer(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000100697(gene)|ensembl:ENST00000541352(transcript)|intact:EBI-395506(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ZtGfyeV0VRqis5DZzVvbPwVAVC09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P49366 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-741925|ensembl:ENSP00000210060|uniprotkb:Q13184|uniprotkb:Q13276|uniprotkb:A8K688|uniprotkb:Q9UDG0|uniprotkb:M0R1I5 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dhys_human(display_long)|uniprotkb:DHPS(gene name)|psi-mi:DHPS(display_short)|uniprotkb:DS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001193903.1|ensembl:ENSG00000095059(gene)|ensembl:ENST00000210060(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008216"(spermidine metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008612"(peptidyl-lysine modification to peptidyl-hypusine)|go:"GO:0034038"(deoxyhypusine synthase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR002773(Deoxyhypusine synthase)|interpro:IPR029035|interpro:IPR036982|mint:P49366|rcsb pdb:1DHS|rcsb pdb:1RLZ|rcsb pdb:1ROZ|rcsb pdb:1RQD|refseq:NP_001921.1|refseq:NP_037538.1|rcsb pdb:6P4V|rcsb pdb:6PGR|rcsb pdb:6WKZ|rcsb pdb:6WL6|rcsb pdb:6XXH|rcsb pdb:6XXI|rcsb pdb:6XXJ|rcsb pdb:6XXK|rcsb pdb:6XXL|rcsb pdb:6XXM|reactome:R-HSA-204626|refseq:XP_011526072.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:4MuV3m6JWYn3kCENrfcLU6GAkto9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43143 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q00796 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-750068|uniprotkb:B2R655|uniprotkb:Q16682|uniprotkb:Q9UMD6|uniprotkb:B7Z3A6|uniprotkb:J3JZZ5|ensembl:ENSP00000267814 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dhso_human(display_long)|uniprotkb:L-iditol 2-dehydrogenase(gene name synonym)|uniprotkb:SORD(gene name)|psi-mi:SORD(display_short)|uniprotkb:"(R,R)-butanediol dehydrogenase"(gene name synonym)|uniprotkb:Polyol dehydrogenase(gene name synonym)|uniprotkb:Ribitol dehydrogenase(gene name synonym)|uniprotkb:Xylitol dehydrogenase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003095.2|ensembl:ENSG00000140263(gene)|ensembl:ENST00000267814(transcript)|go:"GO:0000721"("(R,R)-butanediol dehydrogenase activity")|go:"GO:0003939"(L-iditol 2-dehydrogenase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006062"(sorbitol catabolic process)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046370"(fructose biosynthetic process)|go:"GO:0046526"(D-xylulose reductase activity)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0050255"(ribitol 2-dehydrogenase activity)|go:"GO:0051160"(L-xylitol catabolic process)|go:"GO:0051164"(L-xylitol metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:Q00796|rcsb pdb:1PL6|rcsb pdb:1PL7|rcsb pdb:1PL8|reactome:R-HSA-5652227|reactome:R-HSA-5661270 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:BGqvXy2I7nmCLPYTOkUcQ8fpCkk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UBM7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1054468|uniprotkb:O60492|uniprotkb:O60717|uniprotkb:B2R6Z2|ensembl:ENSP00000347717|ensembl:ENSP00000384739 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dhcr7_human(display_long)|uniprotkb:"Sterol Delta(7)-reductase"(gene name synonym)|uniprotkb:DHCR7(gene name)|psi-mi:DHCR7(display_short)|uniprotkb:D7SR(gene name synonym)|uniprotkb:Delta7-sterol reductase(gene name synonym)|uniprotkb:Sterol reductase SR-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001157289.1|refseq:NP_001351.2|mint:Q9UBM7|reactome:R-HSA-2426168|reactome:R-HSA-6807047|reactome:R-HSA-6807062|interpro:IPR018083|ensembl:ENSG00000172893(gene)|ensembl:ENST00000355527(transcript)|ensembl:ENST00000407721(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0009918"(sterol delta7 reductase activity)|go:"GO:0016020"(membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016132"(brassinosteroid biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0047598"(7-dehydrocholesterol reductase activity)|go:"GO:0050661"(NADP binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:op53bBpGaOM0Ysy4Bn5q6qXcKgI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P51659 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358398|ensembl:ENSP00000424940|uniprotkb:B4DNV1|uniprotkb:B4DVS5|uniprotkb:E9PB82|uniprotkb:F5HE57 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dhb4_human(display_long)|uniprotkb:HSD17B4(gene name)|psi-mi:HSD17B4(display_short)|uniprotkb:EDH17B4(gene name synonym)|uniprotkb:D-bifunctional protein(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 4(gene name synonym)|uniprotkb:Multifunctional protein 2(gene name synonym)|uniprotkb:SDR8C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 8C member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000405.1|refseq:NP_001186220.1|refseq:NP_001186221.1|refseq:NP_001278956.1|refseq:NP_001278957.1|ensembl:ENSG00000133835(gene)|ensembl:ENST00000510025(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0033989"(3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity)|go:"GO:0036111"(very long-chain fatty-acyl-CoA metabolic process)|go:"GO:0036112"(medium-chain fatty-acyl-CoA metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0060009"(Sertoli cell development)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR029069|interpro:IPR036291|interpro:IPR036527|rcsb pdb:1IKT|rcsb pdb:1S9C|rcsb pdb:1ZBQ|rcsb pdb:6Z1W|rcsb pdb:6Z1X|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:i3A0dh9gAO2vfrCYXvo2U6+PwJQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P15924 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|uniprotkb:D7RX09|ensembl:ENSP00000369129 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001305963.1|refseq:NP_001008844.1|refseq:NP_004406.2|go:"GO:0014704"(intercalated disc)|go:"GO:0005916"(fascia adherens)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-109N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8TEH3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-8796791|intact:EBI-28967334|ensembl:ENSP00000362727|uniprotkb:Q05C88|uniprotkb:D3PFD3|uniprotkb:Q8IVD6|uniprotkb:Q9H796|uniprotkb:B1AM80|uniprotkb:Q6PJZ5|uniprotkb:Q5VWF0|uniprotkb:B7Z669|uniprotkb:A8MZA3|uniprotkb:B7Z3C8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:den1a_human(display_long)|uniprotkb:Connecdenn 1(gene name synonym)|uniprotkb:FAM31A(gene name synonym)|uniprotkb:KIAA1608(gene name synonym)|uniprotkb:Protein FAM31A(gene name synonym)|uniprotkb:DENND1A(gene name)|psi-mi:DENND1A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENST00000373618|ensembl:ENSP00000362720|ensembl:ENST00000373620|ensembl:ENSP00000362722|ensembl:ENSP00000362727|go:"GO:0030425"(dendrite)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|go:"GO:0030136"(clathrin-coated vesicle)|interpro:IPR037516|interpro:IPR043153|rcsb pdb:6EKK|reactome:R-HSA-8876198|interpro:IPR040032|ensembl:ENSG00000119522(gene)|ensembl:ENST00000373624(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0017124"(SH3 domain binding)|refseq:NP_065997.1|refseq:NP_079096.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:FAi3e2/uMk7/cXHabR2lzbEINUo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P26196 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P17844 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q86XP3-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399290|ensembl:ENSP00000352308 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q86xp3-2(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-722353(isoform-parent)|ensembl:ENSG00000198231(gene)|ensembl:ENST00000359353(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Q243mS5S0gaP0GZwzWpJo3gEk+w9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UJV9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1046350|ensembl:ENSP00000330349|uniprotkb:Q96BK6|uniprotkb:Q96K05|uniprotkb:Q9NT96|uniprotkb:Q9NW04|uniprotkb:B2RDC8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ddx41_human(display_long)|uniprotkb:DEAD box protein 41(gene name synonym)|uniprotkb:DEAD box protein abstrakt homolog(gene name synonym)|uniprotkb:DDX41(gene name)|psi-mi:DDX41(display_short)|uniprotkb:ABS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000183258(gene)|ensembl:ENST00000330503(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044113|mint:Q9UJV9|rcsb pdb:2P6N|rcsb pdb:5GVS|rcsb pdb:5H1Y|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-3270619|rcsb pdb:5GVR|refseq:NP_057306.2|refseq:NP_001308661.1|refseq:NP_001308759.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:a3HNDsQBaXs/1q8ZXjkcMgEhPes9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00571-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399283|ensembl:ENSP00000392494 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o00571-2(display_long)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000215301(gene)|ensembl:ENST00000457138(transcript)|intact:EBI-353779(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:5SxnZCFJwg8W6hNGI7CQfQom5E49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NR30-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-6654714|ensembl:ENSP00000480334 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9nr30-2(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:DEAD box protein 21(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-357942(isoform-parent)|ensembl:ENSG00000165732(gene)|ensembl:ENST00000620315(transcript)|uniprotkb:Q9NR30-2(isoform-parent) - - isoform-comment:Contains a N-acetylmethionine at position 1. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:G4lZy34GneSNYW02rbAZ+Yhm9j09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UHI6 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92841 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92499 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358474|ensembl:ENSP00000233084|ensembl:ENSP00000370745|ensembl:ENSP00000413767|ensembl:ENSP00000504080|uniprotkb:B4DME8|uniprotkb:B4DPN6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ddx1_human(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:DEAD box protein retinoblastoma(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000079785(gene)|ensembl:ENST00000233084(transcript)|ensembl:ENST00000381341(transcript)|ensembl:ENST00000434671(transcript)|ensembl:ENST00000677302(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|refseq:NP_004930.1|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071920"(cleavage body)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR043136|mint:Q92499|rcsb pdb:4XW3|reactome:R-HSA-6784531|dip:DIP-38163N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:n2Zv07BpuUDT32/ttDzIFXH3yIQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8IZD4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NPI6 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8IWE4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-15794102|ensembl:ENSP00000319482|ensembl:ENSP00000454762|uniprotkb:B3KVY4 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dcnl3_human(display_long)|uniprotkb:DCUN1D3(gene name)|psi-mi:DCUN1D3(display_short)|uniprotkb:SCCRO3(gene name synonym)|uniprotkb:DCUN1 domain-containing protein 3(gene name synonym)|uniprotkb:Defective in cullin neddylation protein 1-like protein 3(gene name synonym)|uniprotkb:Squamous cell carcinoma-related oncogene 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000188215(gene)|ensembl:ENST00000324344(transcript)|ensembl:ENST00000563934(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032182"(ubiquitin-like protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045116"(protein neddylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2000435"(negative regulation of protein neddylation)|go:"GO:2000436"(positive regulation of protein neddylation)|interpro:IPR005176(Protein of unknown function DUF298)|interpro:IPR014764(Defective in cullin neddylation)|interpro:IPR042460|rcsb pdb:4GBA|reactome:R-HSA-8951664|refseq:NP_775746.1|dip:DIP-60769N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:mm1cxzEu3wERC4LSX9V7qT9yB089606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P61962 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P08174-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399275|ensembl:ENSP00000316333 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p08174-2(display_long)|uniprotkb:CD55(gene name)|psi-mi:CD55(display_short)|uniprotkb:CR(gene name synonym)|uniprotkb:DAF(gene name synonym)|uniprotkb:DAF-1(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000196352(gene)|ensembl:ENST00000314754(transcript)|intact:EBI-1033846(isoform-parent)|uniprotkb:P08174-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:PJEQBwVqqCkdWRQRTcO3STT1YFE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P98082-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399269|ensembl:ENSP00000426245|ensembl:ENSP00000439919 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p98082-3(display_long)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym)|uniprotkb:Differentially-expressed protein 2(gene name synonym)|uniprotkb:DAB2(gene name)|psi-mi:DAB2(display_short)|uniprotkb:DOC2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1171238(isoform-parent)|ensembl:ENSG00000153071(gene)|ensembl:ENST00000509337(transcript)|ensembl:ENST00000545653(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:m7zSXYqvPBGjCIkTUXKcEufJqDk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:D6RIU2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399261|ensembl:ENSP00000427385 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:d6riu2_human(display_long)|uniprotkb:CLDND1(gene name)|psi-mi:CLDND1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000080822(gene)|ensembl:ENST00000503621(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR042356 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ogwza8I99rhqsCvuwbcfkPt24i09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q5M775-4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965309|ensembl:ENSP00000378901 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q5m775-4(display_long)|uniprotkb:SPECC1(gene name)|psi-mi:SPECC1(display_short)|uniprotkb:CYTSB(gene name synonym)|uniprotkb:NSP5(gene name synonym)|uniprotkb:Nuclear structure protein 5(gene name synonym)|uniprotkb:Sperm antigen HCMOGT-1(gene name synonym)|uniprotkb:Sperm antigen with calponin homology and coiled-coil domains 1(gene name synonym)|uniprotkb:NSP5alpha3beta(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000128487(gene)|ensembl:ENST00000395530(transcript)|intact:EBI-350473(isoform-parent) - - isoform-comment:Initiator Met-1 is removed. Contains a N-myristoyl glycine at position 2. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:6vw12KYobZ+tGQRufNyVOakiNTU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q69YQ0 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351113|uniprotkb:O15081|intact:EBI-10965349|uniprotkb:B7Z758|uniprotkb:F5H1H6|ensembl:ENSP00000325785|ensembl:ENSP00000393363|ensembl:ENSP00000439633 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cytsa_human(display_long)|uniprotkb:SPECC1L(gene name)|psi-mi:SPECC1L(display_short)|uniprotkb:Renal carcinoma antigen NY-REN-22(gene name synonym)|uniprotkb:CYTSA(gene name synonym)|uniprotkb:KIAA0376(gene name synonym)|uniprotkb:Sperm antigen with calponin homology and coiled-coil domains 1-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_056145.4|refseq:NP_001241661.2|dip:DIP-33173N|ensembl:ENSG00000100014(gene)|ensembl:ENST00000314328(transcript)|ensembl:ENST00000437398(transcript)|ensembl:ENST00000541492(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005921"(gap junction)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0051301"(cell division)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR040166|mint:Q69YQ0 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:iYg2RCRo/dMtmwyppU7ywkhkolI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9P0U4-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-12743307|ensembl:ENSP00000390475 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9p0u4-2(display_long)|uniprotkb:CXXC1(gene name)|psi-mi:CXXC1(display_short)|uniprotkb:CFP1(gene name synonym)|uniprotkb:CGBP(gene name synonym)|uniprotkb:CpG-binding protein(gene name synonym)|uniprotkb:PCCX1(gene name synonym)|uniprotkb:PHD finger and CXXC domain-containing protein 1(gene name synonym)|uniprotkb:PHF18(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000154832(gene)|ensembl:ENST00000412036(transcript)|intact:EBI-949911(isoform-parent)|uniprotkb:Q9P0U4-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:xbbetWt89EVR6HhPeMAzK9u1yI09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P78310-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399252 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p78310-2(display_long)|uniprotkb:CVB3-binding protein(gene name synonym)|uniprotkb:Coxsackievirus B-adenovirus receptor(gene name synonym)|uniprotkb:HCVADR(gene name synonym)|uniprotkb:CAR2(isoform synonym)|uniprotkb:HCAR2(isoform synonym)|uniprotkb:TVV(isoform synonym)|uniprotkb:CXADR(gene name)|psi-mi:CXADR(display_short)|uniprotkb:CAR(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-747931(isoform-parent)|uniprotkb:P78310-2(isoform-parent) - - isoform-comment:"Ref.14 (AAD31772) sequence is in conflict in position: 343:P->A." figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Dg4yjuVG7NgxfiStRoHP4fZzruc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P17302 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1103439|uniprotkb:Q6FHU1|uniprotkb:Q9Y5I8|uniprotkb:B2R5U9|ensembl:ENSP00000282561|ensembl:ENSP00000497283|ensembl:ENSP00000497367|ensembl:ENSP00000497565 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cxa1_human(display_long)|uniprotkb:GJAL(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)|uniprotkb:GJA1(gene name)|psi-mi:GJA1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|ensembl:ENSG00000152661(gene)|ensembl:ENST00000282561(transcript)|ensembl:ENST00000647564(transcript)|ensembl:ENST00000649003(transcript)|ensembl:ENST00000650427(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P17302|rcsb pdb:2LL2|reactome:R-HSA-190704|reactome:R-HSA-190827|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-190873|reactome:R-HSA-191650|reactome:R-HSA-196025|reactome:R-HSA-9013406|reactome:R-HSA-9013409|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042311"(vasodilation)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:1905867"(epididymis development)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|refseq:NP_000156.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ri2cG7YGyM1rVOXreP305UK1h4U9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60716-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399246|ensembl:ENSP00000354907 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o60716-3(display_long)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-701927(isoform-parent)|ensembl:ENSG00000198561(gene)|ensembl:ENST00000361796(transcript) - - isoform-comment:Contains a phosphothreonine at position 916. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:g1fjQgOwVLA3sgl4rgL8jjjOo989606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P35222 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P35221 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BY42 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1045669|uniprotkb:Q9BYL7|uniprotkb:Q9HCV9|uniprotkb:Q9NX29|uniprotkb:Q9NZZ8|uniprotkb:Q9P002|uniprotkb:Q9UHW3|uniprotkb:E1P5Z9|ensembl:ENSP00000349906 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rtf2_human(display_long)|uniprotkb:RTF2(gene name)|psi-mi:RTF2(display_short)|uniprotkb:C20orf43(gene name synonym)|uniprotkb:RTFDC1(gene name synonym)|uniprotkb:Replication termination factor 2 domain-containing protein 1(gene name synonym)|uniprotkb:AD-007(orf name)|uniprotkb:CDA05(orf name)|uniprotkb:HSPC164(orf name)|uniprotkb:HSPC169(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001269964.1|refseq:NP_001269965.1|refseq:NP_001269966.1|refseq:NP_057491.2|ensembl:ENSG00000022277(gene)|go:"GO:0003677"(DNA binding)|ensembl:ENST00000357348(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0071171"(site-specific DNA replication termination at RTS1 barrier)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1902979"(mitotic DNA replication termination)|interpro:IPR006735(Protein of unknown function DUF602)|interpro:IPR027799 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:eh/6sc/MIM9QOLgd0NfZaezJ7ek9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BT78 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|ensembl:ENSP00000264389|uniprotkb:B3KST5 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000138663(gene)|refseq:NP_057213.2|refseq:NP_001244935.1|go:"GO:0016607"(nuclear speck)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|ensembl:ENST00000264389(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|refseq:NP_001317656.1|dip:DIP-34516N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UNS2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|ensembl:ENSP00000268717|uniprotkb:B4DY81 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001186054.1|refseq:NP_003644.2|ensembl:ENSG00000141030(gene)|ensembl:ENST00000268717(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009416"(response to light stimulus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037753|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|rcsb pdb:6R6H|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|refseq:XP_005256894.1|dip:DIP-32478N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14936-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11041710|ensembl:ENSP00000494183 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o14936-3(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1215506(isoform-parent)|ensembl:ENSG00000147044(gene)|ensembl:ENST00000644347(transcript)|uniprotkb:O14936-3(isoform-parent) - - isoform-comment:Contains a phosphoserine at position 571. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:d4K07hNSxQ6SzevpdPbxIOMmuHQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P68400 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8IVT2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2555085|intact:EBI-28972337|ensembl:ENSP00000215582 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:misp_human(display_long)|uniprotkb:MISP(gene name)|psi-mi:MISP(display_short)|uniprotkb:C19orf21(gene name synonym)|uniprotkb:Mitotic spindle positioning protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_775752.1|ensembl:ENSP00000215582|refseq:XP_011525987.1|refseq:XP_011525988.1|ensembl:ENSG00000099812(gene)|ensembl:ENST00000215582(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0016477"(cell migration)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051301"(cell division)|go:"GO:0051640"(organelle localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904776"(regulation of protein localization to cell cortex)|interpro:IPR029304|interpro:IPR042779 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HJ0vL2U8LEer8c+rWNdKxkOv2g89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P46109 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UKF6 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q99829 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1642542|uniprotkb:E1P5Q4|uniprotkb:Q6IBL3|uniprotkb:Q9H243|uniprotkb:Q9NTZ7|ensembl:ENSP00000336945|ensembl:ENSP00000380585 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cpne1_human(display_long)|uniprotkb:CPNE1(gene name)|psi-mi:CPNE1(display_short)|uniprotkb:CPN1(gene name synonym)|uniprotkb:Copine I(gene name synonym)|uniprotkb:Chromobindin 17(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003906.2|refseq:NP_690902.1|refseq:NP_690903.1|refseq:NP_690904.1|refseq:NP_690905.1|ensembl:ENSG00000214078(gene)|ensembl:ENST00000352393(transcript)|ensembl:ENST00000397443(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005215"(transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|interpro:IPR035892|interpro:IPR036465|interpro:IPR037768|mint:Q99829|reactome:R-HSA-1483206|reactome:R-HSA-6798695 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Mtq9BQZT1fdT+JigvKinqBWAh9w9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6FI81 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-750511|uniprotkb:O75206|uniprotkb:O75207|uniprotkb:Q9H0W1|uniprotkb:Q9P1L7|uniprotkb:A8K8B6|ensembl:ENSP00000377914 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cpin1_human(display_long)|uniprotkb:Cytokine-induced apoptosis inhibitor 1(gene name synonym)|uniprotkb:CIAPIN1(gene name)|psi-mi:CIAPIN1(display_short)|uniprotkb:PRO0915(orf name)|uniprotkb:CUA001(orf name)|uniprotkb:Fe-S cluster assembly protein DRE2 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_064709.2|refseq:NP_001295276.1|refseq:NP_001295287.1|dip:DIP-61697N|go:"GO:0006915"(apoptotic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|rcsb pdb:2LD4|rcsb pdb:2YUI|rcsb pdb:4M7R|reactome:R-HSA-2564830|ensembl:ENSG00000005194(gene)|ensembl:ENST00000394391(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:80r/MAg7g8AcGJc7SGHsjE5aWiA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9ULV4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351384|uniprotkb:Q9NSK5|uniprotkb:B3KU12|ensembl:ENSP00000261401|ensembl:ENSP00000438341|intact:EBI-4404698|uniprotkb:A7MAP0|uniprotkb:A7MAP1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cor1c_human(display_long)|uniprotkb:CORO1C(gene name)|psi-mi:CORO1C(display_short)|uniprotkb:CRNN4(gene name synonym)|uniprotkb:Coronin-3(gene name synonym)|uniprotkb:hCRNN4(gene name synonym)|uniprotkb:CRN2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001263400.1|refseq:NP_055140.1|ensembl:ENSG00000110880(gene)|ensembl:ENST00000261401(transcript)|ensembl:ENST00000541050(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0090148"(membrane fission)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0016197"(endosomal transport)|go:"GO:0097750"(endosome membrane tubulation)|go:"GO:0140285"(endosome fission)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027333|interpro:IPR036322|mint:Q9ULV4|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|refseq:NP_001098707.1|refseq:XP_016874610.1|refseq:XP_016874611.1|refseq:XP_016874612.1|dip:DIP-33138N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Em/LQxjBk9n4tobk5ksyDfFSyeU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BR76 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y678 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1049127|uniprotkb:A8K6M8|uniprotkb:B3KMF6|uniprotkb:Q54AC4|ensembl:ENSP00000325002 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:copg1_human(display_long)|uniprotkb:COPG1(gene name)|psi-mi:COPG1(display_short)|uniprotkb:COPG(gene name synonym)|uniprotkb:Gamma-1-coat protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_057212.1|ensembl:ENSG00000181789(gene)|ensembl:ENST00000314797(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9Y678|rcsb pdb:1R4X|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-29872N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:P3wujl1rJH+o0vUUl/rLp0PEpMU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P23528 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629|ensembl:ENSP00000432660 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005498.1|ensembl:ENSG00000172757(gene)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|ensembl:ENST00000308162(transcript)|ensembl:ENST00000525451(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009615"(response to virus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0031258"(lamellipodium membrane)|dip:DIP-33000N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q53SF7-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399083 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q53sf7-2(display_long)|uniprotkb:COBLL1(gene name)|psi-mi:COBLL1(display_short)|uniprotkb:KIAA0977(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-2835780(isoform-parent)|uniprotkb:Q53SF7(isoform-parent)|uniprotkb:Q53SF7-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:u/eD1NLYQr5Ym3/iGOLR1zbMhKk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75128 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3446582|uniprotkb:A4D257|uniprotkb:B7ZLW9|uniprotkb:B9EGF8|uniprotkb:Q8TCM1|uniprotkb:Q8N304|uniprotkb:A7E2B0|uniprotkb:Q86XA7|uniprotkb:Q504Y4|uniprotkb:Q2T9J3|intact:EBI-28974386|ensembl:ENSP00000265136 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cobl_human(display_long)|uniprotkb:COBL(gene name)|psi-mi:COBL(display_short)|uniprotkb:KIAA0633(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000265136|ensembl:ENST00000395540|ensembl:ENSP00000378910|ensembl:ENST00000395542|ensembl:ENSP00000378912|ensembl:ENST00000441453|ensembl:ENSP00000399500|refseq:XP_011513537.1|refseq:NP_056013.2|refseq:NP_001274365.1|refseq:NP_001274367.1|refseq:NP_001333370.1|refseq:NP_001333371.1|refseq:NP_001333372.1|refseq:NP_001333373.1|ensembl:ENSG00000106078(gene)|ensembl:ENST00000265136(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001726"(ruffle)|go:"GO:0001757"(somite specification)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0016020"(membrane)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030903"(notochord development)|go:"GO:0033504"(floor plate development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048565"(digestive tract development)|go:"GO:0048669"(collateral sprouting in absence of injury)|go:"GO:0051639"(actin filament network formation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990357"(terminal web)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR019025|interpro:IPR039895|mint:O75128|rcsb pdb:4PL8 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:mkEX2B5sVoK8CD6RWVVCp912otg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8IWV2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2028276|uniprotkb:Q8IX14|uniprotkb:Q8TC35|uniprotkb:B2RAX3|ensembl:ENSP00000380602|ensembl:ENSP00000396010|ensembl:ENSP00000413642 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cntn4_human(display_long)|uniprotkb:CNTN4(gene name)|psi-mi:CNTN4(display_short)|uniprotkb:Brain-derived immunoglobulin superfamily protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:XP_011531727.1|refseq:XP_011531728.1|refseq:XP_011531729.1|refseq:XP_011531730.1|refseq:XP_011531731.1|refseq:XP_011531732.1|refseq:NP_001193884.1|refseq:NP_001193885.1|refseq:NP_783200.1|refseq:NP_783302.1|refseq:XP_016861271.1|refseq:XP_016861272.1|refseq:XP_016861273.1|ensembl:ENSG00000144619(gene)|ensembl:ENST00000397461(transcript)|ensembl:ENST00000418658(transcript)|ensembl:ENST00000427331(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|reactome:R-HSA-163125 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:bEuIzCrzCxpUO3SU+TBgVQly0aI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15417 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2371691|uniprotkb:B4DFK6|uniprotkb:B4DP09|uniprotkb:F8WA86|uniprotkb:Q6FHA7|ensembl:ENSP00000359225 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cnn3_human(display_long)|uniprotkb:CNN3(gene name)|psi-mi:CNN3(display_short)|uniprotkb:Calponin, acidic isoform(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001830.1|refseq:NP_001272984.1|refseq:NP_001272985.1|refseq:XP_016855734.1|ensembl:ENSG00000117519(gene)|ensembl:ENST00000370206(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:UgeW769u9WgYLYNzTZ50xQqB5I09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q99439 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2961712|ensembl:ENSP00000263097|uniprotkb:Q92578|uniprotkb:A5D8U8|uniprotkb:D6W5X9|uniprotkb:A6NFI4 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cnn2_human(display_long)|uniprotkb:CNN2(gene name)|psi-mi:CNN2(display_short)|uniprotkb:Calponin H2, smooth muscle(gene name synonym)|uniprotkb:Neutral calponin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000064666(gene)|ensembl:ENST00000263097(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045296"(cadherin binding)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR029974|interpro:IPR036872|rcsb pdb:1WYN|reactome:R-HSA-6798695|reactome:R-HSA-8950505|refseq:NP_004359.1|refseq:NP_958434.1|refseq:NP_001290428.1|refseq:NP_001290430.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:64KRSh4MEocrTZ8EuTz9ni8ahhc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P09543-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-9088367|ensembl:ENSP00000377466 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p09543-2(display_long)|uniprotkb:DNAI(isoform synonym)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1059219(isoform-parent)|ensembl:ENSG00000173786(gene)|ensembl:ENST00000393888(transcript)|uniprotkb:P09543-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:SjBMCdDayBiWIFuNnb687QFl8MQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P10909-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399180 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p10909-2(display_long)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:1(isoform synonym)|uniprotkb:CLU34(isoform synonym)|uniprotkb:Sulfated glycoprotein 2(gene name synonym)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1104674(isoform-parent)|uniprotkb:P10909-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ViPwBY4HDabSpU8hw7ogR+rS34o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q00610-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10963396|ensembl:ENSP00000376763 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q00610-2(display_long)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000141367(gene)|ensembl:ENST00000393043(transcript)|intact:EBI-354967(isoform-parent)|uniprotkb:Q00610-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:kv+aVWhj1cM/1s6De8Baz2GC5649606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P09497-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965328|ensembl:ENSP00000310812 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p09497-2(display_long)|uniprotkb:CLTB(gene name)|psi-mi:CLTB(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-726598(isoform-parent)|ensembl:ENSG00000175416(gene)|ensembl:ENST00000345807(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:r047u2aiXuVM26p1k2gGk3R5ucw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P09496-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-4401010|ensembl:ENSP00000242284 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p09496-2(display_long)|uniprotkb:CLTA(gene name)|psi-mi:CLTA(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1171169(isoform-parent)|ensembl:ENSG00000122705(gene)|ensembl:ENST00000345519(transcript)|uniprotkb:P09496-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:0k8RkZBtJhE5Dd3a/4GBwaTT1gw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q07065 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H8K7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-714785|uniprotkb:Q0P6C6|uniprotkb:Q8N597|ensembl:ENSP00000419126 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:paat_human(display_long)|uniprotkb:PAAT(gene name)|psi-mi:PAAT(display_short)|uniprotkb:C10orf88(gene name synonym)|uniprotkb:Protein associated with ABC transporters(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000119965(gene)|ensembl:ENST00000481909(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0042802"(identical protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR028043|refseq:NP_079218.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:FVQBSowK05RlKodgqYZ71aHgU689606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9P2M7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-79537|intact:EBI-28986579|ensembl:ENSP00000271636|uniprotkb:Q5T386|uniprotkb:Q9NR25|uniprotkb:A6H8L3|uniprotkb:A7MD22 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cing_human(display_long)|uniprotkb:CGN(gene name)|psi-mi:CGN(display_short)|uniprotkb:KIAA1319(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000143375(gene)|ensembl:ENST00000271636(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016459"(myosin complex)|go:"GO:0030054"(cell junction)|go:"GO:0045296"(cadherin binding)|interpro:IPR002928(Myosin tail)|mint:Q9P2M7|reactome:R-HSA-2173791|refseq:NP_065821.1|ensembl:ENSP00000271636|refseq:XP_005245422.1|dip:DIP-30947N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RJ4soprXOGUAlMLVIikuoeMs3v09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O76071 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UHD1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399174|ensembl:ENSP00000401080|ensembl:ENSP00000494044 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9uhd1-2(display_long)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:Protein morgana(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:CHP1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000457199(transcript)|ensembl:ENST00000647220(transcript)|intact:EBI-2550959(isoform-parent)|uniprotkb:Q9UHD1-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:jZUa8wLINKmgKpYoQDiwuUo6OKI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H444 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UNE7-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399167|ensembl:ENSP00000456875|ensembl:ENSP00000457228 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9une7-2(display_long)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:PP1131(orf name)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:CHIP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-357085(isoform-parent)|uniprotkb:Q9UNE7-2(isoform-parent)|ensembl:ENSG00000103266(gene)|ensembl:ENST00000564370(transcript)|ensembl:ENST00000565677(transcript) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:BjkNiDgZRysZDbU4tBaI8TVJzUs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P10809 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P49715 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1172054|uniprotkb:A7LNP2|uniprotkb:Q05CA4|uniprotkb:P78319|ensembl:ENSP00000427514 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cebpa_human(display_long)|uniprotkb:CEBPA(gene name)|psi-mi:CEBPA(display_short)|uniprotkb:CEBP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000245848(gene)|ensembl:ENST00000498907(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048469"(cell maturation)|go:"GO:0048839"(inner ear development)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P49715|rcsb pdb:6DC0|reactome:R-HSA-381340|reactome:R-HSA-9616222|refseq:NP_004355.2|refseq:NP_001272758.1|refseq:NP_001274353.1|refseq:NP_001274364.1|dip:DIP-37882N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:uo2VMV1hbdAvsRxr6yU2EVW11nY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q99618 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-739534|uniprotkb:A8K5V6|uniprotkb:D3DUS6|ensembl:ENSP00000442068|ensembl:ENSP00000446339 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cdca3_human(display_long)|uniprotkb:CDCA3(gene name)|psi-mi:CDCA3(display_short)|uniprotkb:Trigger of mitotic entry protein 1(gene name synonym)|uniprotkb:Gene-rich cluster protein C8(gene name synonym)|uniprotkb:C8(gene name synonym)|uniprotkb:GRCC8(gene name synonym)|uniprotkb:TOME1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001284532.1|refseq:NP_001284533.1|refseq:NP_112589.1|ensembl:ENST00000535406(transcript)|ensembl:ENST00000538862(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|interpro:IPR038832|ensembl:ENSG00000111665(gene)|refseq:NP_001317948.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:UmhACVP83jo9/xqP7qDSSvKgiAo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y5K6 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-298152|uniprotkb:A6NL34|uniprotkb:Q5VYA3|uniprotkb:Q9UG97|ensembl:ENSP00000352264 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cd2ap_human(display_long)|uniprotkb:CD2AP(gene name)|psi-mi:CD2AP(display_short)|uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)|uniprotkb:Adapter protein CMS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000198087(gene)|ensembl:ENST00000359314(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031941"(filamentous actin)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9Y5K6|rcsb pdb:2FEI|rcsb pdb:2J6F|rcsb pdb:2J6K|rcsb pdb:2J6O|rcsb pdb:2J7I|rcsb pdb:3AA6|rcsb pdb:3LK4|rcsb pdb:3U23|rcsb pdb:4WCI|rcsb pdb:4X1V|rcsb pdb:7DS6|rcsb pdb:7DS8|reactome:R-HSA-373753|refseq:NP_036252.1|dip:DIP-31807N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:T0OYMq1jOCwVMJOxnrPg5Jm4CGw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8ND76 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1049189|uniprotkb:Q2M3V4|uniprotkb:Q2TU96|uniprotkb:Q6NT86|uniprotkb:Q7Z4U7|uniprotkb:Q8TEX2|uniprotkb:Q8TEX3|uniprotkb:Q96M99|uniprotkb:Q96P45|uniprotkb:B7ZKX9|uniprotkb:D3DRY9|ensembl:ENSP00000363836 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ccny_human(display_long)|uniprotkb:Cyclin fold protein 1(gene name synonym)|uniprotkb:Cyclin box protein 1(gene name synonym)|uniprotkb:CCNY(gene name)|psi-mi:CCNY(display_short)|uniprotkb:C10orf9(gene name synonym)|uniprotkb:CBCP1(gene name synonym)|uniprotkb:CFP1(gene name synonym)|uniprotkb:cyclin-X(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_659449.3|refseq:NP_859049.2|refseq:NP_001269781.1|refseq:NP_001269782.1|refseq:NP_001269783.1|refseq:XP_011517660.1|refseq:XP_011517662.1|refseq:XP_011517663.1|refseq:XP_011517664.1|refseq:XP_011517665.1|refseq:XP_011517666.1|refseq:XP_011517667.1|refseq:XP_011517668.1|refseq:XP_011517669.1|refseq:XP_011517670.1|refseq:XP_016871328.1|refseq:XP_016871329.1|refseq:XP_016871330.1|ensembl:ENSG00000108100(gene)|ensembl:ENST00000374704(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000308"(cytoplasmic cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR012399(Uncharacterised conserved protein CG14939, cyclin region)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|mint:Q8ND76 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HilQRrRscMCl9sjGletD/fYyTI89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P47755 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-762451|uniprotkb:B4DG50|ensembl:ENSP00000354947 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:caza2_human(display_long)|uniprotkb:CapZ alpha-2(gene name synonym)|uniprotkb:CAPZA2(gene name)|psi-mi:CAPZA2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006127.1|ensembl:ENSG00000198898(gene)|ensembl:ENST00000361183(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47755|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-9662360|reactome:R-HSA-983231|go:"GO:0016020"(membrane) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:7+0w8fJ0OowIwAC7/tdNqiGSepc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P52907 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14444-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399158|ensembl:ENSP00000374296|ensembl:ENSP00000434204 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q14444-2(display_long)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:RNG105(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1047080(isoform-parent)|ensembl:ENSG00000135387(gene)|ensembl:ENST00000389645(transcript)|ensembl:ENST00000530820(transcript) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:nY6bmHyNuKXqs6PP91n9+WWBx7s9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P27797 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q05682-4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399149|ensembl:ENSP00000354513|ensembl:ENSP00000398826 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q05682-4(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym)|uniprotkb:WI-38 L-CAD II(isoform synonym)|uniprotkb:1-CAD(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1642116(isoform-parent)|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361901(transcript)|ensembl:ENST00000417172(transcript) - - isoform-comment:"Contains a phosphoserine at position 202. Contains a glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) at position 209." figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:IwqiO4Xm4Z/XmRtP6uUKkWv/po89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BY67 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-5652260|uniprotkb:Q86WB8|uniprotkb:Q8N2F4|uniprotkb:A4FVB5|uniprotkb:F5H0J4|uniprotkb:H0YGA7|uniprotkb:H1ZZV9|uniprotkb:H1ZZW1|uniprotkb:H1ZZW2|uniprotkb:X5D2C8|ensembl:ENSP00000395359 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cadm1_human(display_long)|uniprotkb:CADM1(gene name)|psi-mi:CADM1(display_short)|uniprotkb:IGSF4(gene name synonym)|uniprotkb:IGSF4A(gene name synonym)|uniprotkb:NECL2(gene name synonym)|uniprotkb:SYNCAM(gene name synonym)|uniprotkb:TSLC1(gene name synonym)|uniprotkb:Immunoglobulin superfamily member 4(gene name synonym)|uniprotkb:Nectin-like protein 2(gene name synonym)|uniprotkb:Spermatogenic immunoglobulin superfamily(gene name synonym)|uniprotkb:Synaptic cell adhesion molecule(gene name synonym)|uniprotkb:Tumor suppressor in lung cancer 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001287972.1|refseq:NP_001287973.1|refseq:NP_001287974.1|refseq:NP_001091987.1|refseq:NP_055148.3|dip:DIP-57599N|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045202"(synapse)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0051606"(detection of stimulus)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9BY67|rcsb pdb:3BIN|rcsb pdb:4H5S|reactome:R-HSA-418990|reactome:R-HSA-420597|go:"GO:0030165"(PDZ domain binding)|ensembl:ENSG00000182985(gene)|ensembl:ENST00000452722(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002376"(immune system process)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008037"(cell recognition)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030154"(cell differentiation) - - crc64:CDEDE1E0C08BDD3A figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:870cLsl7OEZV3iLs+IaE2V/UW4o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P12830 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13137 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-739580|uniprotkb:B4DDC4|uniprotkb:E7ENK0|uniprotkb:Q53FQ5|uniprotkb:Q53HB5|uniprotkb:Q6IBN9|uniprotkb:Q9BTF7|uniprotkb:B2RBT0|ensembl:ENSP00000258947|uniprotkb:B4E0C0|uniprotkb:E7ETP5|uniprotkb:B4DDT4|uniprotkb:B4DP36|uniprotkb:E9PBE5 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:caco2_human(display_long)|uniprotkb:CALCOCO2(gene name)|psi-mi:CALCOCO2(display_short)|uniprotkb:NDP52(gene name synonym)|uniprotkb:Nuclear domain 10 protein NDP52(gene name synonym)|uniprotkb:Antigen nuclear dot 52 kDa protein(gene name synonym)|uniprotkb:Nuclear dot protein 52(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001248319.1|refseq:NP_001248320.1|refseq:NP_001248322.1|refseq:NP_005822.1|ensembl:ENSG00000136436(gene)|ensembl:ENST00000258947(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0016605"(PML body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098792"(xenophagy)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR041611|interpro:IPR041641|mint:Q13137|rcsb pdb:2MXP|rcsb pdb:3VVV|rcsb pdb:3VVW|rcsb pdb:4GXL|rcsb pdb:4HAN|rcsb pdb:4XKL|rcsb pdb:5AAQ|rcsb pdb:5Z7A|rcsb pdb:5Z7L|refseq:NP_001248324.1|dip:DIP-57534N - - crc64:609B121DA1A9DCB8 figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:N/GPJUGBK+Dh5Cg+csmafphuo9M9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9P1Z2-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399141|ensembl:ENSP00000447647 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9p1z2-2(display_long)|uniprotkb:Calphoglin(gene name synonym)|uniprotkb:Coiled-coil coactivator protein(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-3(gene name synonym)|uniprotkb:PP13275(orf name)|uniprotkb:UNQ2436/PRO4996(orf name)|uniprotkb:CALCOCO1(gene name)|psi-mi:CALCOCO1(display_short)|uniprotkb:KIAA1536(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-749920(isoform-parent)|ensembl:ENSG00000012822(gene)|ensembl:ENST00000548263(transcript)|uniprotkb:Q9P1Z2-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:2mWnXtLxaenmKLT95F7hL+iSLCA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H425 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11022412|uniprotkb:A8K8R8|uniprotkb:G5EA08|uniprotkb:B3KTW1|intact:EBI-11090756|ensembl:ENSP00000355623 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ca198_human(display_long)|uniprotkb:C1orf198(gene name)|psi-mi:C1orf198(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:XP_016858088.1|refseq:NP_001129966.1|refseq:NP_001129967.1|refseq:NP_116189.1|ensembl:ENSG00000119280(gene)|ensembl:ENST00000366663(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR031600 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:vPJ0HFpmqJM83LuTIWhqgJyySUg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q07021 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q7L1Q6-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399134|ensembl:ENSP00000394316 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q7l1q6-3(display_long)|uniprotkb:Protein Orf(gene name synonym)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000082153(gene)|ensembl:ENST00000452790(transcript)|intact:EBI-1046727(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:fLiACYEla9w4qnuSzjfnN1VrOr09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43684-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10973830|ensembl:ENSP00000357851 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o43684-2(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1050987(isoform-parent)|ensembl:ENSG00000154473(gene)|ensembl:ENST00000368858(transcript)|uniprotkb:O43684-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:09UCXnVgc+bSYbygg0KVJjt9f7c9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q10589 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2476339|ensembl:ENSP00000252593|intact:EBI-2839059|uniprotkb:A8K4Y4|uniprotkb:Q53G07 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:bst2_human(display_long)|uniprotkb:BST2(gene name)|psi-mi:BST2(display_short)|uniprotkb:Tetherin(gene name synonym)|uniprotkb:HM1.24 antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0005886"(plasma membrane)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR024886|rcsb pdb:2LK9|rcsb pdb:2X7A|rcsb pdb:2XG7|rcsb pdb:3MQ7|rcsb pdb:3MQ9|rcsb pdb:3MQB|rcsb pdb:3MQC|rcsb pdb:3NWH|rcsb pdb:4P6Z|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0051607"(defense response to virus)|rcsb pdb:6DFF|go:"GO:0070062"(extracellular exosome)|go:"GO:0070665"(positive regulation of leukocyte proliferation)|go:"GO:1901253"(negative regulation of intracellular transport of viral material)|reactome:R-HSA-6798695|reactome:R-HSA-909733|ensembl:ENSG00000130303(gene)|ensembl:ENST00000252593(transcript)|go:"GO:0002737"(negative regulation of plasmacytoid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|refseq:NP_004326.1|dip:DIP-53216N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:vunnCOscGahFdaeN03pDo/8xW7I9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NSY1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1383367|uniprotkb:O94791|uniprotkb:Q8IYF2|uniprotkb:Q8N2G7|uniprotkb:Q8NHG9|uniprotkb:Q9NTG8|uniprotkb:Q4W5H2|intact:EBI-28972938|ensembl:ENSP00000424668 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:bmp2k_human(display_long)|uniprotkb:BMP2K(gene name)|psi-mi:BMP2K(display_short)|uniprotkb:BIKE(gene name synonym)|uniprotkb:HRIHFB2017(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000424668|ensembl:ENST00000502871|ensembl:ENSP00000421768|refseq:NP_060063.2|refseq:NP_942595.1|ensembl:ENSG00000138756(gene)|ensembl:ENST00000502613(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR026105|interpro:IPR028182|rcsb pdb:4W9W|rcsb pdb:4W9X|rcsb pdb:5I3O|rcsb pdb:5I3R|rcsb pdb:5IKW|go:"GO:0019208"(phosphatase regulator activity) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ckhpP0erhSRURf04YvQFCsYZ8rY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8NFC6 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2654318|uniprotkb:Q9NTD6|uniprotkb:Q96AL1|uniprotkb:Q9H6G0|uniprotkb:Q6P0M8|uniprotkb:Q9P2L9|ensembl:ENSP00000040738 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:bd1l1_human(display_long)|uniprotkb:BOD1L1(gene name)|psi-mi:BOD1L1(display_short)|uniprotkb:BOD1L(gene name synonym)|uniprotkb:FAM44A(gene name synonym)|uniprotkb:KIAA1327(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_683692.2|ensembl:ENSG00000038219(gene)|ensembl:ENST00000040738(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR043244|mint:Q8NFC6 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/sFfw7CP8rOZG3hZNsT0npwIZIQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P80723 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281|ensembl:ENSP00000482066 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788(gene)|ensembl:ENST00000322611(transcript)|ensembl:ENST00000616743(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0008406"(gonad development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0031982"(vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:2001076"(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:X+L20HKimV3J+vLnQljg+x78+e09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UL15-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399128|ensembl:ENSP00000338814 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9ul15-2(display_long)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-356517(isoform-parent)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000337322(transcript)|uniprotkb:Q9UL15-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:z+Rgw1tAnQeQ7q7XTrGFqwVxbkg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14965 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-448680|uniprotkb:O60445|uniprotkb:O75873|uniprotkb:Q9BQD6|uniprotkb:Q9UPG5|uniprotkb:E1P5F9|ensembl:ENSP00000216911|ensembl:ENSP00000321591|ensembl:ENSP00000360407|ensembl:ENSP00000379247|ensembl:ENSP00000379249|ensembl:ENSP00000379250|ensembl:ENSP00000379251 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:aurka_human(display_long)|uniprotkb:AIRK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 15(gene name synonym)|uniprotkb:Aurora/IPL1-related kinase 1(gene name synonym)|uniprotkb:Breast tumor-amplified kinase(gene name synonym)|uniprotkb:STK6(gene name synonym)|uniprotkb:AIK(gene name synonym)|uniprotkb:ARK1(gene name synonym)|uniprotkb:AURA(gene name synonym)|uniprotkb:BTAK(gene name synonym)|uniprotkb:STK15(gene name synonym)|uniprotkb:AURKA(gene name)|psi-mi:AURKA(display_short)|uniprotkb:AYK1(gene name synonym)|uniprotkb:IAK1(gene name synonym)|uniprotkb:Aurora 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 6(gene name synonym)|uniprotkb:Serine/threonine-protein kinase aurora-A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003591.2|refseq:NP_940835.1|refseq:NP_940836.1|refseq:NP_940837.1|refseq:NP_940838.1|refseq:NP_940839.1|refseq:NP_001310232.1|refseq:NP_001310233.1|refseq:NP_001310234.1|refseq:XP_016883524.1|dip:DIP-33068N|rcsb pdb:3LAU|rcsb pdb:3M11|rcsb pdb:3MYG|rcsb pdb:3NRM|rcsb pdb:3O50|rcsb pdb:3O51|rcsb pdb:3P9J|rcsb pdb:3QBN|rcsb pdb:3R21|rcsb pdb:3R22|rcsb pdb:3UNZ|rcsb pdb:3UO4|rcsb pdb:3UO5|rcsb pdb:3UO6|rcsb pdb:3UOD|rcsb pdb:3UOH|rcsb pdb:3UOJ|rcsb pdb:3UOK|rcsb pdb:3UOL|rcsb pdb:3UP2|rcsb pdb:3UP7|rcsb pdb:3W10|rcsb pdb:3W16|rcsb pdb:3W18|rcsb pdb:3W2C|rcsb pdb:4B0G|rcsb pdb:4BN1|rcsb pdb:4BYI|rcsb pdb:4BYJ|rcsb pdb:4C3P|rcsb pdb:4C3R|rcsb pdb:4CEG|rcsb pdb:4DEA|rcsb pdb:4DEB|rcsb pdb:4DED|rcsb pdb:4DEE|rcsb pdb:4DHF|rcsb pdb:4J8M|rcsb pdb:4J8N|rcsb pdb:4JAI|rcsb pdb:4JAJ|rcsb pdb:4JBO|rcsb pdb:4JBP|rcsb pdb:4JBQ|rcsb pdb:4O0S|rcsb pdb:4O0U|rcsb pdb:4O0W|rcsb pdb:4PRJ|rcsb pdb:4UYN|rcsb pdb:4UZD|rcsb pdb:4UZH|rcsb pdb:4ZS0|rcsb pdb:3VAP|rcsb pdb:4ZTQ|rcsb pdb:4ZTR|rcsb pdb:5AAD|rcsb pdb:5AAE|rcsb pdb:5AAF|rcsb pdb:5AAG|rcsb pdb:5DN3|rcsb pdb:5DNR|rcsb pdb:5DOS|rcsb pdb:5DPV|rcsb pdb:5DR2|rcsb pdb:5DR6|rcsb pdb:5DR9|rcsb pdb:5DRD|rcsb pdb:5DT0|rcsb pdb:5DT3|rcsb pdb:5DT4|rcsb pdb:5EW9|rcsb pdb:5G15|rcsb pdb:5G1X|rcsb pdb:5L8J|rcsb pdb:5L8K|rcsb pdb:5L8L|rcsb pdb:5LXM|rcsb pdb:5OBJ|rcsb pdb:5OBR|rcsb pdb:5ODT|rcsb pdb:5ONE|rcsb pdb:5ORL|rcsb pdb:5ORN|rcsb pdb:5ORO|rcsb pdb:5ORP|rcsb pdb:5ORR|rcsb pdb:5ORS|rcsb pdb:5ORT|rcsb pdb:5ORV|rcsb pdb:5ORW|rcsb pdb:5ORX|rcsb pdb:5ORY|rcsb pdb:5ORZ|rcsb pdb:5OS0|rcsb pdb:5OS1|rcsb pdb:5OS2|rcsb pdb:5OS3|rcsb pdb:5OS4|rcsb pdb:5OS5|rcsb pdb:5OS6|rcsb pdb:5OSD|rcsb pdb:5OSE|rcsb pdb:5OSF|rcsb pdb:5ZAN|rcsb pdb:6C2R|rcsb pdb:6C2T|rcsb pdb:6C83|rcsb pdb:6CPE|rcsb pdb:6CPF|rcsb pdb:6CPG|rcsb pdb:6GRA|rcsb pdb:6HJJ|rcsb pdb:6HJK|rcsb pdb:6I2U|rcsb pdb:6R49|rcsb pdb:6R4A|rcsb pdb:6R4B|rcsb pdb:4ZTS|rcsb pdb:6R4C|rcsb pdb:6R4D|rcsb pdb:6VPG|rcsb pdb:6VPH|rcsb pdb:6VPI|rcsb pdb:6VPJ|rcsb pdb:6VPL|rcsb pdb:6VPM|rcsb pdb:6XKA|rcsb pdb:6Z4Y|rcsb pdb:7AYH|rcsb pdb:7AYI|reactome:R-HSA-174178|reactome:R-HSA-2565942|reactome:R-HSA-4615885|reactome:R-HSA-6804114|reactome:R-HSA-6804756|reactome:R-HSA-8854050|reactome:R-HSA-8854518|reactome:R-HSA-8854521|ensembl:ENSG00000087586(gene)|ensembl:ENST00000312783(transcript)|ensembl:ENST00000347343(transcript)|ensembl:ENST00000371356(transcript)|ensembl:ENST00000395911(transcript)|ensembl:ENST00000395913(transcript)|ensembl:ENST00000395914(transcript)|ensembl:ENST00000395915(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0009611"(response to wounding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030496"(midbody)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032133"(chromosome passenger complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0042585"(germinal vesicle)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043203"(axon hillock)|go:"GO:0045120"(pronucleus)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097421"(liver regeneration)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:2C6D|rcsb pdb:2C6E|rcsb pdb:2DWB|rcsb pdb:2J4Z|rcsb pdb:2J50|rcsb pdb:2NP8|rcsb pdb:2W1C|rcsb pdb:2W1D|rcsb pdb:2W1E|rcsb pdb:2W1F|interpro:IPR030611|rcsb pdb:2W1G|rcsb pdb:2WQE|rcsb pdb:2WTV|rcsb pdb:2WTW|rcsb pdb:2X6D|rcsb pdb:2X6E|rcsb pdb:2X81|rcsb pdb:2XNE|rcsb pdb:2XNG|rcsb pdb:2XRU|rcsb pdb:3COH|rcsb pdb:3E5A|rcsb pdb:3EFW|rcsb pdb:3FDN|interpro:IPR030616|mint:O14965|rcsb pdb:1MQ4|rcsb pdb:1MUO|rcsb pdb:1OL5|rcsb pdb:1OL6|rcsb pdb:1OL7|rcsb pdb:2BMC|rcsb pdb:3H0Y|rcsb pdb:3H0Z|rcsb pdb:3H10|rcsb pdb:3HA6|rcsb pdb:3K5U - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:UT4ih1hMN2xMvAC3hDznAJOW+/E9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8WWM7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P54709 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P05023-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399123|ensembl:ENSP00000358508 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p05023-3(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-358778(isoform-parent)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000369496(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:m/AvVHYmVUOgvRmD8pJSZyHuRKY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UBL3-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16130425|ensembl:ENSP00000395310 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9ubl3-3(display_long)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym)|uniprotkb:ASH2-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000129691(gene)|ensembl:ENST00000428278(transcript)|intact:EBI-540797(isoform-parent) - - isoform-comment:No experimental confirmation available. Contains a N-acetylmethionine at position 1. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ERKOFmIONf8FkZlCUVcFrYjIpck9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O15144 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:v5OozQTt614rvrBBoUavbAzjgZ49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P61158 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P61160 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-353580|ensembl:ENSP00000260641|uniprotkb:O15142|uniprotkb:Q96C82|uniprotkb:B2RCP5|uniprotkb:D6W5F4|uniprotkb:E9PF41 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:arp2_human(display_long)|uniprotkb:ACTR2(gene name)|psi-mi:ACTR2(display_short)|uniprotkb:ARP2(gene name synonym)|uniprotkb:Actin-like protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000138071(gene)|ensembl:ENST00000260641(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008306"(associative learning)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0016482"(cytosolic transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0030478"(actin cap)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0045471"(response to ethanol)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:NP_001005386.1|refseq:NP_005713.1|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:P61160|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33165N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:URQsZpIsMtsFZAnpLYDDvgKcPqA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8N6T3-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-6288865|ensembl:ENSP00000314615 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q8n6t3-2(display_long)|uniprotkb:ARFGAP1(gene name)|psi-mi:ARFGAP1(display_short)|uniprotkb:ARF1GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor 1 GTPase-activating protein(gene name synonym)|uniprotkb:ARF1-directed GTPase-activating protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-716933(isoform-parent)|ensembl:ENSG00000101199(gene)|ensembl:ENST00000353546(transcript)|uniprotkb:Q8N6T3-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:u+yn46US/e/Uc45ydi8QOL5Hjuk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O15143 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802|ensembl:ENSP00000389631|ensembl:ENSP00000398110|ensembl:ENSP00000403211|ensembl:ENSP00000410238|ensembl:ENSP00000494033|ensembl:ENSP00000496599 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005711.1|ensembl:ENSG00000130429(gene)|ensembl:ENST00000427217(transcript)|ensembl:ENST00000431816(transcript)|ensembl:ENST00000451682(transcript)|ensembl:ENST00000455009(transcript)|ensembl:ENST00000458033(transcript)|ensembl:ENST00000645391(transcript)|ensembl:ENST00000646101(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032355"(response to estradiol)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0036284"(tubulobulbar complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030141|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92747 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1020827|uniprotkb:Q7Z5U8|uniprotkb:Q86WU5|uniprotkb:Q8IXQ0|uniprotkb:A4D276|uniprotkb:D6W5S1|ensembl:ENSP00000262942|uniprotkb:B4DLQ7 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:arc1a_human(display_long)|uniprotkb:ARPC1A(gene name)|psi-mi:ARPC1A(display_short)|uniprotkb:SOP2L(gene name synonym)|uniprotkb:SOP2-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006400.2|ensembl:ENSG00000241685(gene)|ensembl:ENST00000262942(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q92747|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33142N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ACqXC+XYl9R9Z7mHhpw7vt1SPu49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P02649 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1222467|uniprotkb:C0JYY5|uniprotkb:Q9P2S4|uniprotkb:B2RC15|ensembl:ENSP00000252486 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:apoe_human(display_long)|uniprotkb:APOE(gene name)|psi-mi:APOE(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000032.1|refseq:NP_001289617.1|refseq:NP_001289618.1|refseq:NP_001289619.1|refseq:NP_001289620.1|dip:DIP-1120N|ensembl:ENSG00000130203(gene)|ensembl:ENST00000252486(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010467"(gene expression)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010877"(lipid transport involved in lipid storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0017038"(protein import)|go:"GO:0019068"(virion assembly)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032805"(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034447"(very-low-density lipoprotein particle clearance)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046907"(intracellular transport)|go:"GO:0046911"(metal chelating activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0051651"(maintenance of location in cell)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061771"(response to caloric restriction)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071830"(triglyceride-rich lipoprotein particle clearance)|go:"GO:0071831"(intermediate-density lipoprotein particle clearance)|go:"GO:0072562"(blood microparticle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901627"(negative regulation of postsynaptic membrane organization)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1902999"(negative regulation of phospholipid efflux)|go:"GO:1903001"(negative regulation of lipid transport across blood-brain barrier)|go:"GO:1903002"(positive regulation of lipid transport across blood-brain barrier)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905855"(positive regulation of heparan sulfate binding)|go:"GO:1905860"(positive regulation of heparan sulfate proteoglycan binding)|go:"GO:1905890"(regulation of cellular response to very-low-density lipoprotein particle stimulus)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:1990777"(lipoprotein particle)|go:"GO:2000822"(regulation of behavioral fear response)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P02649|rcsb pdb:1B68|rcsb pdb:1BZ4|rcsb pdb:1EA8|rcsb pdb:1GS9|rcsb pdb:1H7I|rcsb pdb:1LE2|rcsb pdb:1LE4|rcsb pdb:1LPE|rcsb pdb:1NFN|rcsb pdb:1NFO|rcsb pdb:1OEF|rcsb pdb:1OEG|rcsb pdb:1OR2|rcsb pdb:1OR3|rcsb pdb:2KC3|rcsb pdb:2KNY|rcsb pdb:2L7B|rcsb pdb:6IWB|rcsb pdb:6NCN|rcsb pdb:6NCO|reactome:R-HSA-1251985|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-8864260|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964058|reactome:R-HSA-9029569|reactome:R-HSA-975634|reactome:R-HSA-977225 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:vnCU03+HdGblqtALKeOTZRx5/3E9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96CW1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965256|ensembl:ENSP00000371894|ensembl:ENSP00000409081 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96cw1-2(display_long)|uniprotkb:AP2M1(gene name)|psi-mi:AP2M1(display_short)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:Adaptin-mu2(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)|uniprotkb:CLAPM1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:HA2 50 kDa subunit(gene name synonym)|uniprotkb:KIAA0109(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000161203(gene)|ensembl:ENST00000382456(transcript)|ensembl:ENST00000439647(transcript)|intact:EBI-297683(isoform-parent)|uniprotkb:Q96CW1-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zq5vvE0JV87QlpnLDuNVcxK6tNQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P63010-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11529439|ensembl:ENSP00000482835|ensembl:ENSP00000483185 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p63010-2(display_long)|uniprotkb:ADTB2(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:CLAPB1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP2B1(gene name)|psi-mi:AP2B1(display_short)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-432924(isoform-parent)|uniprotkb:P63010-2(isoform-parent)|ensembl:ENSG00000006125(gene)|ensembl:ENST00000610402(transcript)|ensembl:ENST00000618940(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RpFHKbLgdxGqagTUoCCgQ2W+9nw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O94973 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1642835|uniprotkb:O75403|uniprotkb:Q96SI8|uniprotkb:Q53ET1|ensembl:ENSP00000413234 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ap2a2_human(display_long)|uniprotkb:AP2A2(gene name)|psi-mi:AP2A2(display_short)|uniprotkb:ADTAB(gene name synonym)|uniprotkb:CLAPA2(gene name synonym)|uniprotkb:HYPJ(gene name synonym)|uniprotkb:KIAA0899(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Huntingtin-interacting protein J(gene name synonym)|uniprotkb:Huntingtin yeast partner J(gene name synonym)|uniprotkb:HIP9(gene name synonym)|uniprotkb:Huntingtin-interacting protein 9(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001229766.1|refseq:NP_036437.1|ensembl:ENST00000448903(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0140312"(cargo adaptor activity)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O94973|reactome:R-HSA-167590|ensembl:ENSG00000183020(gene)|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-6798695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:sda1msOBssgmBiU3ZfSyk3z7/jc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O95782-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965313|ensembl:ENSP00000346246 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o95782-2(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-353552(isoform-parent)|ensembl:ENSG00000196961(gene)|ensembl:ENST00000354293(transcript)|uniprotkb:O95782-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:TqGX2+cKSxTF8iah3B57Fg54+949606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y6Q5 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-752250|uniprotkb:Q9BSI8|uniprotkb:B2RDV5|ensembl:ENSP00000250244 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ap1m2_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-2 subunit(gene name synonym)|uniprotkb:Mu-adaptin 2(gene name synonym)|uniprotkb:AP-mu chain family member mu1B(gene name synonym)|uniprotkb:Mu1B-adaptin(gene name synonym)|uniprotkb:AP1M2(gene name)|psi-mi:AP1M2(display_short)|uniprotkb:Adaptor protein complex AP-1 subunit mu-2(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-2(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-2 medium chain 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005489.2|refseq:NP_001287816.1|ensembl:ENSG00000129354(gene)|ensembl:ENST00000250244(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006903"(vesicle targeting)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Zb94TVE2hogjzn1QKDV3vWRNsWo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BXS5 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-541426|ensembl:ENSP00000291439|uniprotkb:Q4TTY5 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ap1m1_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:AP1M1(gene name)|psi-mi:AP1M1(display_short)|uniprotkb:CLTNM(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_115882.1|ensembl:ENSG00000072958(gene)|ensembl:ENST00000291439(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168|mint:Q9BXS5|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001123996.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:B6OVovdusOdmvB0D+RIyhRRga2Q9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43747-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10185819|ensembl:ENSP00000377148 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o43747-2(display_long)|uniprotkb:ADTG(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit gamma-1(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit gamma-1(gene name synonym)|uniprotkb:CLAPG1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 gamma-1 large chain(gene name synonym)|uniprotkb:Gamma1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin subunit gamma-1(gene name synonym)|uniprotkb:AP1G1(gene name)|psi-mi:AP1G1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-447609(isoform-parent)|uniprotkb:O43747-2(isoform-parent)|ensembl:ENSG00000166747(gene)|ensembl:ENST00000393512(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:24TtNY6AEZwi+zmx9JGGiUR5wPY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q10567-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11978055 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q10567-3(display_long)|uniprotkb:AP1B1(gene name)|psi-mi:AP1B1(display_short)|uniprotkb:ADTB1(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)|uniprotkb:BAM22(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:CLAPB2(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1171303(isoform-parent)|uniprotkb:Q10567-3(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:h1weMDNGhZr6IuDw01OstMT/Nds9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P20073-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11975885|ensembl:ENSP00000362012 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p20073-2(display_long)|uniprotkb:ANXA7(gene name)|psi-mi:ANXA7(display_short)|uniprotkb:ANX7(gene name synonym)|uniprotkb:Annexin VII(gene name synonym)|uniprotkb:Annexin-7(gene name synonym)|uniprotkb:SNX(gene name synonym)|uniprotkb:Synexin(gene name synonym)|uniprotkb:OK/SW-cl.95(orf name)|uniprotkb:Annexin VIIa(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-2338704(isoform-parent)|uniprotkb:P20073-2(isoform-parent)|ensembl:ENSG00000138279(gene)|ensembl:ENST00000372921(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pGFqXRMjtDSrLhKef/dX3Dk92Wk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P07355 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14744-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16398987|ensembl:ENSP00000380583 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o14744-2(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000100462(gene)|ensembl:ENST00000397441(transcript)|intact:EBI-351098(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ZOH7W7B8L7/YM+rFyd0f3wXEcSE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q99873-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399024 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q99873-2(display_long)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:V3(isoform synonym)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-78738(isoform-parent)|uniprotkb:Q99873-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:+M26lRdlFMXQBxqrRNaJDvgwD4o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P30533 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-715927|uniprotkb:Q2M310|uniprotkb:Q53HQ3|uniprotkb:Q53HS6|uniprotkb:D3DVR9|ensembl:ENSP00000497444 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:amrp_human(display_long)|uniprotkb:Low density lipoprotein receptor-related protein-associated protein 1(gene name synonym)|uniprotkb:LRPAP1(gene name)|psi-mi:LRPAP1(display_short)|uniprotkb:A2MRAP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002328.1|ensembl:ENSG00000163956(gene)|ensembl:ENST00000650182(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0012505"(endomembrane system)|go:"GO:0031904"(endosome lumen)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035473"(lipase binding)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900116"(extracellular negative regulation of signal transduction)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|interpro:IPR009066(Alpha-2-macroglobulin receptor-associated protein, domain 1)|interpro:IPR010483(Alpha-2-macroglobulin RAP, C-terminal)|interpro:IPR036744|interpro:IPR037999|interpro:IPR038001|interpro:IPR038003|mint:P30533|rcsb pdb:1LRE|rcsb pdb:1NRE|rcsb pdb:1OP1|rcsb pdb:1OV2|rcsb pdb:2FCW|rcsb pdb:2FTU|rcsb pdb:2FYL|rcsb pdb:2P01|rcsb pdb:2P03|dip:DIP-39355N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:TIbL+P1GW4op4Qawa4lpg8iXUaQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P04075 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y2D5-5 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399017 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9y2d5-5(display_long)|uniprotkb:AKAP-KL(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 2(gene name synonym)|uniprotkb:AKAP2(gene name)|psi-mi:AKAP2(display_short)|uniprotkb:KIAA0920(gene name synonym)|uniprotkb:PRKA2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1754555(isoform-parent) - - isoform-comment:"Ref.6 (AAI46864) sequence is in conflict in position: 20:P->L." figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:jhu+kRtP3OKH5bKUa15XsZ3UGjI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13155 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q12904-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-12412735 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q12904-2(display_long)|uniprotkb:AIMP1(gene name)|psi-mi:AIMP1(display_short)|uniprotkb:EMAP2(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p43(gene name synonym)|uniprotkb:SCYE1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1045802(isoform-parent)|uniprotkb:Q12904-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:s0MERGRXKfgBBThSdBYYuLkvZjA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O95433 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-448610|uniprotkb:Q9P060|uniprotkb:Q96IL6|uniprotkb:B2R9L2|uniprotkb:B4DUR9|ensembl:ENSP00000216479 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ahsa1_human(display_long)|uniprotkb:HSPC322(orf name)|uniprotkb:p38(gene name synonym)|uniprotkb:AHSA1(gene name)|psi-mi:AHSA1(display_short)|uniprotkb:C14orf3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_036243.1|refseq:NP_001308370.1|ensembl:ENSG00000100591(gene)|ensembl:ENST00000216479(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|mint:O95433|rcsb pdb:1X53|rcsb pdb:7DMD|rcsb pdb:7DME|go:"GO:0051879"(Hsp90 protein binding) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HUgJrOxubEHSPst5ZQNxSC38QvY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q09666 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q16186 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NRN7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-740884|ensembl:ENSP00000278618|uniprotkb:Q9C068|uniprotkb:Q9P0Q3|uniprotkb:Q9UG80|uniprotkb:Q9Y389|uniprotkb:B2R6D1|uniprotkb:B4DDW7 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:adppt_human(display_long)|uniprotkb:4'-phosphopantetheinyl transferase(gene name synonym)|uniprotkb:Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase(gene name synonym)|uniprotkb:LYS5 ortholog(gene name synonym)|uniprotkb:AASDHPPT(gene name)|psi-mi:AASDHPPT(display_short)|uniprotkb:CGI-80(orf name)|uniprotkb:HAH-P(orf name)|uniprotkb:HSPC223(orf name)|uniprotkb:x0005(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_056238.2|ensembl:ENSG00000149313(gene)|ensembl:ENST00000278618(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008897"(holo-[acyl-carrier-protein] synthase activity)|go:"GO:0015939"(pantothenate metabolic process)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008278(4'-phosphopantetheinyl transferase)|interpro:IPR037143|rcsb pdb:2BYD|rcsb pdb:2C43|rcsb pdb:2CG5|reactome:R-HSA-199220 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:0S9gDK0HeJ+8eoM5vHaJDW3THAY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UEY8-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11118757|ensembl:ENSP00000277900|ensembl:ENSP00000353286 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9uey8-2(display_long)|uniprotkb:ADD3(gene name)|psi-mi:ADD3(display_short)|uniprotkb:ADDL(gene name synonym)|uniprotkb:Adducin-like protein 70(gene name synonym)|uniprotkb:Short(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-2838698(isoform-parent)|ensembl:ENSG00000148700(gene)|ensembl:ENST00000277900(transcript)|ensembl:ENST00000360162(transcript)|uniprotkb:Q9UEY8-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:NMZfMWdTkFM3xxkUGsdKGBQndWs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P35611-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11030777|ensembl:ENSP00000498269 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p35611-2(display_long)|uniprotkb:ADDA(gene name synonym)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym)|uniprotkb:ADD1(gene name)|psi-mi:ADD1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000087274(gene)|ensembl:ENST00000651918(transcript)|intact:EBI-2809187(isoform-parent)|uniprotkb:P35611-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:oJ2LhoNf3skHWRXHdwXgfB64wk09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P00813 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3904496|uniprotkb:Q53F92|uniprotkb:Q6LA59|ensembl:ENSP00000361965 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ada_human(display_long)|uniprotkb:ADA(gene name)|psi-mi:ADA(display_short)|uniprotkb:ADA1(gene name synonym)|uniprotkb:Adenosine aminohydrolase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000013.2|dip:DIP-371N|ensembl:ENSG00000196839(gene)|ensembl:ENST00000372874(transcript)|go:"GO:0000255"(allantoin metabolic process)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001821"(histamine secretion)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001883"(purine nucleoside binding)|go:"GO:0001889"(liver development)|go:"GO:0001890"(placenta development)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0002636"(positive regulation of germinal center formation)|go:"GO:0002686"(negative regulation of leukocyte migration)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004000"(adenosine deaminase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006154"(adenosine catabolic process)|go:"GO:0006157"(deoxyadenosine catabolic process)|go:"GO:0006196"(AMP catabolic process)|go:"GO:0007568"(aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032261"(purine nucleotide salvage)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033632"(regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042110"(T cell activation)|go:"GO:0042323"(negative regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043101"(purine-containing compound salvage)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0043278"(response to morphine)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046059"(dAMP catabolic process)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0046103"(inosine biosynthetic process)|go:"GO:0046111"(xanthine biosynthetic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046936"(2'-deoxyadenosine deaminase activity)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048541"(Peyer's patch development)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0060169"(negative regulation of adenosine receptor signaling pathway)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0060407"(negative regulation of penile erection)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0070256"(negative regulation of mucus secretion)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006330(Adenosine deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR028893|interpro:IPR032466|rcsb pdb:1M7M|rcsb pdb:3IAR|reactome:R-HSA-74217 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ecvLRFAvATmWKAH4KZ2HAjHgchw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P61163 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-774234|uniprotkb:P42024|uniprotkb:B2R6B0|ensembl:ENSP00000358921 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:actz_human(display_long)|uniprotkb:Centrosome-associated actin homolog(gene name synonym)|uniprotkb:Actin-RPV(gene name synonym)|uniprotkb:ARP1(gene name synonym)|uniprotkb:ACTR1A(gene name)|psi-mi:ACTR1A(display_short)|uniprotkb:CTRN1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005727.1|ensembl:ENSG00000138107(gene)|ensembl:ENST00000369905(transcript)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P61163|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:aJHKOSj1qmZ7Pk8aZAyWWd8DEdw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43707 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|ensembl:ENSP00000252699|ensembl:ENSP00000489220|uniprotkb:A4K467 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004915.2|ensembl:ENSG00000130402(gene)|ensembl:ENSG00000282844(gene)|ensembl:ENST00000252699(transcript)|ensembl:ENST00000634960(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|dip:DIP-33179N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P12814 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:guTURyt26f1ort4NAlYyabNc+WE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H568 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10306917|uniprotkb:Q96M75|uniprotkb:Q13104|ensembl:ENSP00000364555|ensembl:ENSP00000481590 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:actl8_human(display_long)|uniprotkb:ACTL8(gene name)|psi-mi:ACTL8(display_short)|uniprotkb:Cancer/testis antigen 57(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_110439.2|refseq:XP_011540514.1|ensembl:ENSG00000117148(gene)|ensembl:ENST00000375406(transcript)|ensembl:ENST00000617065(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005869"(dynactin complex)|go:"GO:0030855"(epithelial cell differentiation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR043129 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:iHdcioMxSyQC7+b0hiji62JIMCg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P63261 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P68032 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P53396-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399011|ensembl:ENSP00000345398|ensembl:ENSP00000377474 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p53396-2(display_long)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000131473(gene)|ensembl:ENST00000353196(transcript)|ensembl:ENST00000393896(transcript)|intact:EBI-1042794(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pBJJcwGUAn6Tyx0dgKPXQtcoLFE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14639-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399003|ensembl:ENSP00000376682 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o14639-2(display_long)|uniprotkb:Actin-binding LIM protein family member 1(gene name synonym)|uniprotkb:Actin-binding double zinc finger protein(gene name synonym)|uniprotkb:Limatin(gene name synonym)|uniprotkb:ABLIM1(gene name)|psi-mi:ABLIM1(display_short)|uniprotkb:ABLIM(gene name synonym)|uniprotkb:KIAA0059(gene name synonym)|uniprotkb:LIMAB1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-487024(isoform-parent)|ensembl:ENSG00000099204(gene)|ensembl:ENST00000392955(transcript)|uniprotkb:O14639-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:NKlF60PWiHSgdAUP4i81t3H/MyM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8IUX4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11306991|uniprotkb:Q7Z2N2|uniprotkb:B0QYD4|uniprotkb:Q45F03|uniprotkb:Q6ICH3|uniprotkb:Q7Z2N5|ensembl:ENSP00000309749 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:abc3f_human(display_long)|uniprotkb:APOBEC3F(gene name)|psi-mi:APOBEC3F(display_short)|uniprotkb:Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001006667.1|refseq:NP_660341.2|ensembl:ENSG00000128394(gene)|ensembl:ENST00000308521(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0016554"(cytidine to uridine editing)|go:"GO:0030895"(apolipoprotein B mRNA editing enzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0047844"(deoxycytidine deaminase activity)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070383"(DNA cytosine deamination)|go:"GO:0080111"(DNA demethylation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|rcsb pdb:3WUS|rcsb pdb:4IOU|rcsb pdb:4J4J|rcsb pdb:5HX4|rcsb pdb:5HX5|rcsb pdb:5W2M|rcsb pdb:6NIL|refseq:XP_016884132.1|dip:DIP-59966N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:UQApMs/hHRGAKejbOlOwc2tVp+Q9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P54619 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q2M2I8-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965264|ensembl:ENSP00000385181 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q2m2i8-2(display_long)|uniprotkb:AAK1(gene name)|psi-mi:AAK1(display_short)|uniprotkb:Adaptor-associated kinase 1(gene name synonym)|uniprotkb:KIAA1048(gene name synonym)|uniprotkb:AAK1S(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1383433(isoform-parent)|ensembl:ENSG00000115977(gene)|ensembl:ENST00000406297(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:DH8DkUULuzRh2/D20pq1Z4t0fSI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6PD74 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-719906|uniprotkb:Q6FI86|uniprotkb:Q7Z5X9|uniprotkb:Q9H0P1|uniprotkb:Q9HAK0|intact:EBI-28970370|ensembl:ENSP00000261880|uniprotkb:B4DG44 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:aagab_human(display_long)|uniprotkb:AAGAB(gene name)|psi-mi:AAGAB(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000261880|ensembl:ENST00000542650|ensembl:ENSP00000440735|ensembl:ENST00000561452|ensembl:ENSP00000453263|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|interpro:IPR019341|ensembl:ENSG00000103591(gene)|ensembl:ENST00000261880(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_078942.3|refseq:NP_001258814.1|refseq:NP_001258815.1|refseq:XP_011520322.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:j7VuJ/o1zLGNaScR0tsQM3q3QyE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P52209 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-372761|uniprotkb:Q9BWD8|intact:EBI-11020895|uniprotkb:A8K2Y9|ensembl:ENSP00000270776|uniprotkb:B4DQJ8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:6pgd_human(display_long)|uniprotkb:PGD(gene name)|psi-mi:PGD(display_short)|uniprotkb:PGDH(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001291380.1|refseq:NP_001291381.1|refseq:NP_002622.2|ensembl:ENSG00000142657(gene)|ensembl:ENST00000270776(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|mint:P52209|rcsb pdb:2JKV|rcsb pdb:4GWG|rcsb pdb:4GWK|rcsb pdb:5UQ9|reactome:R-HSA-71336|interpro:IPR036291 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:SgbOgCLmdWm3QnN6fQfkHG6iunw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P08195-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16398997|ensembl:ENSP00000340815|ensembl:ENSP00000442135|ensembl:ENSP00000505110|ensembl:ENSP00000506006 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p08195-2(display_long)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-702356(isoform-parent)|ensembl:ENSG00000168003(gene)|ensembl:ENST00000338663(transcript)|ensembl:ENST00000544377(transcript)|ensembl:ENST00000680631(transcript)|ensembl:ENST00000681657(transcript) - - isoform-comment:Initiator Met-1 is removed. Contains a N-acetylserine at position 2. Contains a phosphoserine at position 2. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:G4OBxVuYiZt+lYFOSwZaRklIe+A9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NRA8-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11531709|ensembl:ENSP00000342927 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9nra8-2(display_long)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000184708(gene)|ensembl:ENST00000344710(transcript)|intact:EBI-301024(isoform-parent)|uniprotkb:Q9NRA8-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:VQghhcptYh8k783QTJChpGbP/lU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P30153 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P01892 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2839473|uniprotkb:Q9TPY0|uniprotkb:Q29680|uniprotkb:Q29899|uniprotkb:P06338|uniprotkb:P30445|uniprotkb:Q95352|uniprotkb:Q9TQI3|uniprotkb:Q95380|uniprotkb:P30444|uniprotkb:Q9TPX8|uniprotkb:O19619|uniprotkb:P30446|uniprotkb:Q9TQH5|uniprotkb:P10313|uniprotkb:Q9TPX9|uniprotkb:P30514|uniprotkb:Q29837 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:1a02_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A*02(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 rcsb pdb:4MNQ|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5HYJ|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4OV5|rcsb pdb:4UQ3|ensembl:ENSG00000227715|ensembl:ENSP00000448077|ensembl:ENST00000547522|rcsb pdb:5SWQ|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5HHM|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E6I|rcsb pdb:5IRO|rcsb pdb:6D7G|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016567"(protein ubiquitination)|rcsb pdb:5D2L|rcsb pdb:5D2N|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0070971"(endoplasmic reticulum exit site)|rcsb pdb:4WJ5|go:"GO:0003723"(RNA binding)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5E00|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|go:"GO:0031901"(early endosome membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050690"(regulation of defense response to virus by virus)|go:"GO:0060337"(type I interferon signaling pathway)|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0009986"(cell surface)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0046977"(TAP binding)|go:"GO:2000568"(positive regulation of memory T cell activation)|rcsb pdb:3QFD|rcsb pdb:4K7F|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0030670"(phagocytic vesicle membrane)|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:5NMG|rcsb pdb:5NHT|rcsb pdb:5NQK|rcsb pdb:4WUU|rcsb pdb:4E5X|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:4I4W|rcsb pdb:5EOT|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:3TO2|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4EUP|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0042608"(T cell receptor binding)|rcsb pdb:4L3E|ensembl:ENSG00000235657|ensembl:ENSP00000403575|ensembl:ENSP00000447962|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|rcsb pdb:4FTV|rcsb pdb:5E9D|rcsb pdb:5C07|rcsb pdb:5C08|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000457879|ensembl:ENST00000547271|go:"GO:0051290"(protein heterotetramerization)|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5N1Y|go:"GO:0002250"(adaptive immune response)|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:5ENW|reactome:R-HSA-8866654|rcsb pdb:5JZI|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5TEZ|rcsb pdb:5WSH|mint:P01892|rcsb pdb:5N6B|rcsb pdb:5W1W|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0062061"(TAP complex binding)|rcsb pdb:6G3J - - no-uniprot-update:Deprecated HLA-A AC, merged into a different UniProt canonical but we have mutation features in variable positions.|comment:"Allele =A*02:01:01:01"|comment:"Allele =A*02:01:01:01 according to IPD-IMGT/HLA database" figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:oTL0BWZeACoxMc++WgT0XDz+sNg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P62258 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92485 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399091|ensembl:ENSP00000363001|uniprotkb:B7ZB35|uniprotkb:Q5T0Z0|uniprotkb:Q96CB7 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:asm3b_human(display_long)|uniprotkb:ASMLPD(gene name synonym)|uniprotkb:SMPDL3B(gene name)|psi-mi:SMPDL3B(display_short)|uniprotkb:ASML3B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000130768(gene)|ensembl:ENST00000373894(transcript)|go:"GO:0004767"(sphingomyelin phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006685"(sphingomyelin catabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016798"(hydrolase activity, acting on glycosyl bonds)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0046466"(membrane lipid catabolic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR017064(Acid sphingomyelinase-like phosphodiesterase, predicted)|interpro:IPR029052|interpro:IPR041805|refseq:NP_001009568.1|refseq:NP_055289.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:IAxrOG1KYzE47759+qIAha8ApYE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P49327 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y4F1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399510 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9y4f1-2(display_long)|uniprotkb:Chondrocyte-derived ezrin-like protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 2(gene name synonym)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:CDEP(gene name synonym)|uniprotkb:PLEKHC2(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-5235630(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Nbdv1IAKoXrAlmZ6aSVnYP5dNwU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:A4D161 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11960181|ensembl:ENSP00000342576|uniprotkb:Q05CG4|uniprotkb:Q4G0Q7|uniprotkb:Q6P519 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:f221a_human(display_long)|uniprotkb:FAM221A(gene name)|psi-mi:FAM221A(display_short)|uniprotkb:C7orf46(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000188732(gene)|ensembl:ENST00000344962(transcript)|interpro:IPR026755|mint:A4D161|refseq:NP_001120836.1|refseq:NP_001120837.1|refseq:NP_001287861.1|refseq:NP_954587.2|refseq:XP_011513671.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:UzUHn7yeE0pPwhhGwJCSuSsnLPU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O95049 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1171427|uniprotkb:A6NFP3|uniprotkb:Q32N01|uniprotkb:B3KR73|uniprotkb:B4E2W6|uniprotkb:F5H2X0|uniprotkb:F5H4S9|uniprotkb:B3KXZ0|uniprotkb:K7EK22|intact:EBI-10970160|ensembl:ENSP00000439278 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:zo3_human(display_long)|uniprotkb:Zonula occludens protein 3(gene name synonym)|uniprotkb:Zona occludens protein 3(gene name synonym)|uniprotkb:Tight junction protein 3(gene name synonym)|uniprotkb:TJP3(gene name)|psi-mi:TJP3(display_short)|uniprotkb:ZO3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001254489.1|refseq:NP_001254490.1|ensembl:ENSG00000105289(gene)|ensembl:ENST00000541714(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005420(Zona occludens protein ZO-3)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|rcsb pdb:3KFV|go:"GO:0005923"(bicellular tight junction) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:bJciuPizUo/lOq89solMYusjm009606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13148 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BYI3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11065686|uniprotkb:A0A024RA06|uniprotkb:A4D145|uniprotkb:B8ZZJ1|uniprotkb:Q6N010|uniprotkb:Q75MR4|uniprotkb:Q7LDZ4|uniprotkb:Q96MX1|uniprotkb:Q96NQ6|ensembl:ENSP00000403396|intact:EBI-16428864 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hycci_human(display_long)|uniprotkb:FAM126A(gene name)|psi-mi:FAM126A(display_short)|uniprotkb:DRCTNNB1A(gene name synonym)|uniprotkb:Down-regulated by CTNNB1 protein A(gene name synonym)|uniprotkb:Protein FAM126A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_115970.2|refseq:XP_011513891.1|refseq:XP_005249951.1|ensembl:ENSG00000122591(gene)|ensembl:ENST00000432176(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0042552"(myelination)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR018619|rcsb pdb:5DSE|rcsb pdb:6BQ1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:dQX246o/4bB9UkgG+9Be4mIOfxU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UDY2-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-6596236 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9udy2-3(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:X104(gene name synonym)|uniprotkb:ZO2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1042602(isoform-parent)|uniprotkb:Q9UDY2-3(isoform-parent) - - isoform-comment:Produced by alternative promoter usage. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:7VM99F+2jgFgefvYIs8R5uZqii09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q07157 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-79553|uniprotkb:B4E3K1|ensembl:ENSP00000281537|ensembl:ENSP00000484535|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000104067(gene)|ensembl:ENSG00000277401(gene)|ensembl:ENST00000346128(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENST00000621049(transcript)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR035597|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_003248.3|refseq:NP_783297.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H7S9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3957070|uniprotkb:Q5XG76|ensembl:ENSP00000332325 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:zn703_human(display_long)|uniprotkb:ZNF703(gene name)|psi-mi:ZNF703(display_short)|uniprotkb:ZEPPO1(gene name synonym)|uniprotkb:ZPO1(gene name synonym)|uniprotkb:Zinc finger elbow-related proline domain protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000183779(gene)|ensembl:ENST00000331569(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022129|reactome:R-HSA-212436|refseq:NP_079345.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:6o2BN2iquHZVAhS8rqsdMIJrZ0A9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NUD5 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2954851|uniprotkb:Q3B7J3|ensembl:ENSP00000484056|uniprotkb:Q6NT79 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:zchc3_human(display_long)|uniprotkb:ZCCHC3(gene name)|psi-mi:ZCCHC3(display_short)|uniprotkb:C20orf99(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000247315(gene)|ensembl:ENST00000500893(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|interpro:IPR042509|refseq:NP_149080.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:7OjndwgSqExNYquAbdZ2zX2Ploc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O96006 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-740037|uniprotkb:Q96BY4|ensembl:ENSP00000370616|ensembl:ENSP00000370620|ensembl:ENSP00000370621|ensembl:ENSP00000498725 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:zbed1_human(display_long)|uniprotkb:ZBED1(gene name)|psi-mi:ZBED1(display_short)|uniprotkb:ALTE(gene name synonym)|uniprotkb:DREF(gene name synonym)|uniprotkb:KIAA0785(gene name synonym)|uniprotkb:TRAMP(gene name synonym)|uniprotkb:dREF homolog(gene name synonym)|uniprotkb:Putative Ac-like transposable element(gene name synonym)|uniprotkb:DNA replication-related element-binding factor(gene name synonym)|uniprotkb:Zinc finger BED domain-containing protein 1(gene name synonym)|uniprotkb:hDREF(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001164606.1|refseq:NP_001164607.1|refseq:NP_004720.1|ensembl:ENSG00000214717(gene)|ensembl:ENST00000381218(transcript)|ensembl:ENST00000381222(transcript)|ensembl:ENST00000381223(transcript)|ensembl:ENST00000652001(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990466"(protein autosumoylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003656(Zinc finger, BED-type predicted)|interpro:IPR008906(HAT dimerisation)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036236|mint:O96006|rcsb pdb:2CT5|reactome:R-HSA-4551638|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016605"(PML body) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:jl97ZV2Kz5YAmQKktWt/wk7OkRw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6ZSR9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-8770594 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:yj005_human(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 interpro:IPR028182 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/hof6Sm+pnFWS2hEGqOuPgNxipw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P07947 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-515331|uniprotkb:A6NLB3|uniprotkb:D3DUH1|intact:EBI-28995389|ensembl:ENSP00000324740|ensembl:ENSP00000462468 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:yes_human(display_long)|uniprotkb:p61-Yes(gene name synonym)|uniprotkb:Proto-oncogene c-Yes(gene name synonym)|uniprotkb:YES1(gene name)|psi-mi:YES1(display_short)|uniprotkb:YES(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:XP_016881449.1|refseq:NP_005424.1|ensembl:ENSP00000324740|ensembl:ENSP00000462468|dip:DIP-33849N|ensembl:ENSG00000176105(gene)|ensembl:ENST00000314574(transcript)|ensembl:ENST00000584307(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050900"(leukocyte migration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035751|interpro:IPR036028|interpro:IPR036860|mint:P07947|rcsb pdb:2HDA|reactome:R-HSA-1227986|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2682334|reactome:R-HSA-389356|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-8940973|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9670439 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Wo+NWxPVSmF8W6ZHQmTPpg3YuY09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P67809 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P46937 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H0D6-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16398401 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9h0d6-2(display_long)|uniprotkb:XRN2b(isoform synonym)|uniprotkb:DHM1-like protein(gene name synonym)|uniprotkb:XRN2(gene name)|psi-mi:XRN2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-372110(isoform-parent)|uniprotkb:Q9H0D6(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:TVNq+PF/Um+HSvweV62ZMvC8reg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8IZH2-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965083|ensembl:ENSP00000376707 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q8izh2-2(display_long)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000114127(gene)|ensembl:ENST00000392981(transcript)|intact:EBI-372406(isoform-parent)|uniprotkb:Q8IZH2-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:E7g0flI0E0BQBTcMcbjByo6F/eQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P12956 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P13010 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P18887 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-947466|uniprotkb:Q9HCB1|uniprotkb:Q6IBS4|ensembl:ENSP00000262887 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:xrcc1_human(display_long)|uniprotkb:XRCC1(gene name)|psi-mi:XRCC1(display_short)|uniprotkb:X-ray repair cross-complementing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006288.2|dip:DIP-39067N|ensembl:ENSG00000073050(gene)|ensembl:ENST00000262887(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010033"(response to organic substance)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0032356"(oxidized DNA binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904877"(positive regulation of DNA ligase activity)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990599"(3' overhang single-stranded DNA endodeoxyribonuclease activity)|interpro:IPR001357(BRCT)|interpro:IPR002706(DNA-repair protein Xrcc1, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036420|mint:P18887|rcsb pdb:1CDZ|rcsb pdb:1XNA|rcsb pdb:1XNT|rcsb pdb:2D8M|rcsb pdb:2W3O|rcsb pdb:3K75|rcsb pdb:3K77|rcsb pdb:3LQC|rcsb pdb:5E6Q|rcsb pdb:5W7X|rcsb pdb:5W7Y|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:96hETrBzHYhHX9FC5dZpKnFcjDg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6UXN9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P61964 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BV38 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75083 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351917|uniprotkb:O75313|uniprotkb:Q8N6E5|uniprotkb:Q9UG05|uniprotkb:Q9UG78|uniprotkb:A8MPU4|uniprotkb:Q9UQE0|uniprotkb:A8K6E9|ensembl:ENSP00000371890|ensembl:ENSP00000427687 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:wdr1_human(display_long)|uniprotkb:WDR1(gene name)|psi-mi:WDR1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)|uniprotkb:NORI-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005103.2|refseq:NP_059830.1|ensembl:ENSG00000071127(gene)|ensembl:ENST00000382452(transcript)|ensembl:ENST00000499869(transcript)|go:"GO:0002102"(podosome)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0040011"(locomotion)|go:"GO:0042247"(establishment of planar polarity of follicular epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990266"(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O75083|reactome:R-HSA-114608 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ewKq6uA2Wrg/uK31ayOoenA9Gv49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NP79 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-740160|uniprotkb:Q5TGM1|uniprotkb:Q6IAE8|uniprotkb:Q9H0R2|uniprotkb:Q9H3K9|uniprotkb:Q9P0Q0|uniprotkb:E1P594|ensembl:ENSP00000356602|uniprotkb:B4DW55|uniprotkb:E7ETQ7 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:vta1_human(display_long)|uniprotkb:VTA1(gene name)|psi-mi:VTA1(display_short)|uniprotkb:HSPC228(orf name)|uniprotkb:My012(orf name)|uniprotkb:SKD1-binding protein 1(gene name synonym)|uniprotkb:C6orf55(gene name synonym)|uniprotkb:Dopamine-responsive gene 1 protein(gene name synonym)|uniprotkb:LYST-interacting protein 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001273300.1|refseq:NP_001273301.1|refseq:NP_057569.2|rcsb pdb:4TXQ|rcsb pdb:4TXR|rcsb pdb:4U7E|reactome:R-HSA-162588|reactome:R-HSA-917729|ensembl:ENSG00000009844(gene)|ensembl:ENST00000367630(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046755"(viral budding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR023175|interpro:IPR039431|interpro:IPR041212|interpro:IPR044538|rcsb pdb:2LXL|rcsb pdb:2LXM|rcsb pdb:4TXP - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:QIeYrvtJGJ2jWli8PWK9TeO6gus9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q93050-1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10982167|ensembl:ENSP00000377415 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q93050-1(display_long)|uniprotkb:ATP6N1(gene name synonym)|uniprotkb:ATP6N1A(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:VPP1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:II(isoform synonym)|uniprotkb:ATP6V0A1(gene name)|psi-mi:ATP6V0A1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000033627(gene)|ensembl:ENST00000393829(transcript)|intact:EBI-2891238(isoform-parent)|uniprotkb:Q93050-1(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:6xORlarFote90IzU+aWuSIHfR/k9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H9H4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75436 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1043891|uniprotkb:Q8TBH4|uniprotkb:Q9H982|ensembl:ENSP00000263559|ensembl:ENSP00000362480|uniprotkb:B2RDD3|uniprotkb:A8MZ56 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:vp26a_human(display_long)|uniprotkb:VPS26A(gene name)|psi-mi:VPS26A(display_short)|uniprotkb:VPS26(gene name synonym)|uniprotkb:Vesicle protein sorting 26A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000122958(gene)|ensembl:ENST00000263559(transcript)|ensembl:ENST00000373382(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031982"(vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0097422"(tubular endosome)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934|mint:O75436|rcsb pdb:2FAU|rcsb pdb:5F0J|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|reactome:R-HSA-3238698|rcsb pdb:7BLO|refseq:NP_001030337.1|refseq:NP_004887.2|refseq:NP_001305875.1|dip:DIP-29075N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:n0uOd+2HQmRW7koIy678uP0d3+o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60504-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1222956|ensembl:ENSP00000429764|intact:EBI-8080249|intact:EBI-8565573|intact:EBI-8565600|intact:EBI-7503501|intact:EBI-8080170|intact:EBI-8565332|intact:EBI-8565394|intact:EBI-7503561|intact:EBI-8080198|intact:EBI-8080221|intact:EBI-8565438|intact:EBI-8080138|intact:EBI-8597571|intact:EBI-8565301|intact:MINT-262507|intact:EBI-8597400|intact:EBI-8080321 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o60504-2(display_long)|uniprotkb:SORBS3(gene name)|psi-mi:SORBS3(display_short)|uniprotkb:SCAM1(gene name synonym)|uniprotkb:SH3-containing adapter molecule 1(gene name synonym)|uniprotkb:Sorbin and SH3 domain-containing protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000120896(gene)|ensembl:ENST00000523965(transcript)|intact:EBI-741237(vinex_human)|uniprotkb:O60504-2(isoform-parent) - - isoform-comment:Contains a phosphoserine at position 6. Initiator Met-1 is removed. Contains a N-acetylalanine at position 2. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:J/3fJkmrjmQg5ul/KWW06IGy4iM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P18206-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11027067|ensembl:ENSP00000361841 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p18206-2(display_long)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:Vinculin(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-716775(isoform-parent)|ensembl:ENSG00000035403(gene)|ensembl:ENST00000372755(transcript)|uniprotkb:P18206-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:NTtWA0EY5lnB707QOeQCIB2iY4U9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P09327 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q00341 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1049478|uniprotkb:Q9UCY3|uniprotkb:Q53QU2|uniprotkb:B4DTQ2|uniprotkb:E7EM71|intact:EBI-28974616|ensembl:ENSP00000399139 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:vigln_human(display_long)|uniprotkb:High density lipoprotein-binding protein(gene name synonym)|uniprotkb:HDLBP(gene name)|psi-mi:HDLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:VGL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000399139|refseq:NP_005327.1|refseq:NP_976221.1|refseq:NP_001230829.1|refseq:XP_011509360.1|refseq:XP_011509362.1|refseq:XP_016859429.1|ensembl:ENSG00000115677(gene)|ensembl:ENST00000427183(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0045296"(cadherin binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|rcsb pdb:1VIG|rcsb pdb:1VIH|rcsb pdb:2CTE|rcsb pdb:2CTF|rcsb pdb:2CTJ|rcsb pdb:2CTK|rcsb pdb:2CTL|rcsb pdb:2CTM|reactome:R-HSA-8964011|refseq:NP_001307894.1|refseq:NP_001307895.1|refseq:XP_005247059.2|refseq:XP_006712538.1|refseq:XP_005247060.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:4NqKFEjUn5Fi5Ws3tirpanGqYwg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P21283 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-988663|ensembl:ENSP00000379203|ensembl:ENSP00000430282 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:vatc1_human(display_long)|uniprotkb:Vacuolar proton pump subunit C 1(gene name synonym)|uniprotkb:ATP6V1C1(gene name)|psi-mi:ATP6V1C1(display_short)|uniprotkb:ATP6C(gene name synonym)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VATC(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001686.1|go:"GO:0005886"(plasma membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045177"(apical part of cell)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004907(ATPase, V1 complex, subunit C)|interpro:IPR036132|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|ensembl:ENSG00000155097(gene)|ensembl:ENST00000395862(transcript)|ensembl:ENST00000518738(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005215"(transporter activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:8Bvb2tq4GavkgDWnRGz7fb/eQh49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P38606 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1054757|intact:EBI-10982175|uniprotkb:Q53YD9|uniprotkb:Q96DY6|uniprotkb:Q9UHY3|uniprotkb:B2RBR8|uniprotkb:B7Z1R5|uniprotkb:D3DN75|ensembl:ENSP00000273398 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:vata_human(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Vacuolar ATPase isoform VA68(gene name synonym)|uniprotkb:ATP6V1A(gene name)|psi-mi:ATP6V1A(display_short)|uniprotkb:ATP6A1(gene name synonym)|uniprotkb:ATP6V1A1(gene name synonym)|uniprotkb:VPP2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001681.2|ensembl:ENSG00000114573(gene)|ensembl:ENST00000273398(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:P38606|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:GqPRFwsl5tDH83kpE8Al7NiYWrI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15904 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-714667|uniprotkb:Q8NBT4|uniprotkb:Q9H0C7|uniprotkb:A6ZKI4|ensembl:ENSP00000358777 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:vas1_human(display_long)|uniprotkb:V-ATPase S1 accessory protein(gene name synonym)|uniprotkb:V-ATPase Ac45 subunit(gene name synonym)|uniprotkb:Protein XAP-3(gene name synonym)|uniprotkb:ATP6AP1(gene name)|psi-mi:ATP6AP1(display_short)|uniprotkb:ATP6IP1(gene name synonym)|uniprotkb:ATP6S1(gene name synonym)|uniprotkb:VATPS1(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:Vacuolar proton pump subunit S1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001174.2|ensembl:ENSG00000071553(gene)|ensembl:ENST00000369762(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045851"(pH reduction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR008388(ATPase, V1 complex, subunit S1)|mint:Q15904|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-77387|reactome:R-HSA-8980692|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:XP_011529481.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:c5zqmRYvzBfRy1BdJteDGueEjY49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P61421 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-954063|ensembl:ENSP00000290949|uniprotkb:P12953|uniprotkb:Q02547 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:va0d1_human(display_long)|uniprotkb:Vacuolar proton pump subunit d 1(gene name synonym)|uniprotkb:V-ATPase AC39 subunit(gene name synonym)|uniprotkb:V-ATPase 40 kDa accessory protein(gene name synonym)|uniprotkb:32 kDa accessory protein(gene name synonym)|uniprotkb:ATP6V0D1(gene name)|psi-mi:ATP6V0D1(display_short)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VPATPD(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000159720(gene)|ensembl:ENST00000290949(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|mint:P61421|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-381038|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|go:"GO:0016324"(apical plasma membrane)|refseq:NP_004682.2|dip:DIP-47435N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3a/yIxEF9LMwAZUR3npGQrw8xNo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H3U1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10977801|ensembl:ENSP00000377816 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9h3u1-2(display_long)|uniprotkb:UNC45A(gene name)|psi-mi:UNC45A(display_short)|uniprotkb:GCUNC-45(gene name synonym)|uniprotkb:SMAP1(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 1(gene name synonym)|uniprotkb:3(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1048763(isoform-parent)|ensembl:ENSG00000140553(gene)|ensembl:ENST00000394275(transcript)|uniprotkb:Q9H3U1-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:dlj1Yxe0kjoEMS5uEdhIwMh51MQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q04323-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11530712|ensembl:ENSP00000294119 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q04323-2(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000162191(gene)|ensembl:ENST00000294119(transcript)|intact:EBI-1058647(isoform-parent)|uniprotkb:Q04323-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3DD93eyg5bSqmm3twiOfff+2Bps9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q93009 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P45974-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-12072186|ensembl:ENSP00000373883 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p45974-2(display_long)|uniprotkb:USP5(gene name)|psi-mi:USP5(display_short)|uniprotkb:Deubiquitinating enzyme 5(gene name synonym)|uniprotkb:ISOT(gene name synonym)|uniprotkb:Isopeptidase T(gene name synonym)|uniprotkb:Ubiquitin thioesterase 5(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000111667(gene)|ensembl:ENST00000389231(transcript)|intact:EBI-741277(isoform-parent)|uniprotkb:P45974-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:L23hJoJYEeSIJ2TP3s86XQmg+EY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P0CG47 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697|ensembl:ENSP00000379178|ensembl:ENSP00000379180|ensembl:ENSP00000478771 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG47|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|rcsb pdb:2KHW|rcsb pdb:2MBB|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2MRO|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|rcsb pdb:2MSG|go:"GO:1901214"(regulation of neuron death)|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|interpro:IPR000626(Ubiquitin)|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7CAP|rcsb pdb:7JMS|rcsb pdb:7LYC|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-174178|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-983168|reactome:R-HSA-8852276|reactome:R-HSA-8941858|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8856828|reactome:R-HSA-8951664|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|ensembl:ENSG00000170315(gene)|ensembl:ENST00000302182(transcript)|ensembl:ENST00000395837(transcript)|ensembl:ENST00000395839(transcript)|ensembl:ENST00000614404(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BZF9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-350510|uniprotkb:Q14DD3|uniprotkb:Q8N3B8|uniprotkb:Q9HCL1|uniprotkb:Q9NWC6|uniprotkb:G3XAG2|uniprotkb:Q96NH6|intact:EBI-10977773|ensembl:ENSP00000314556 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:uaca_human(display_long)|uniprotkb:UACA(gene name)|psi-mi:UACA(display_short)|uniprotkb:KIAA1561(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001008225.1|refseq:NP_060473.2|dip:DIP-33117N|ensembl:ENSG00000137831(gene)|ensembl:ENST00000322954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030227|interpro:IPR036770|mint:Q9BZF9|reactome:R-HSA-9013407|reactome:R-HSA-9627069 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:F58VkGk2DBsUUrB+wgknUFZhJ+E9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6IBS0 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-722204|uniprotkb:Q9Y3F5|ensembl:ENSP00000303908 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:twf2_human(display_long)|uniprotkb:Twinfilin-1-like protein(gene name synonym)|uniprotkb:A6-related protein(gene name synonym)|uniprotkb:Protein tyrosine kinase 9-like(gene name synonym)|uniprotkb:TWF2(gene name)|psi-mi:TWF2(display_short)|uniprotkb:PTK9L(gene name synonym)|uniprotkb:MSTP011(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_009215.1|ensembl:ENSG00000247596(gene)|ensembl:ENST00000305533(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030016"(myofibril)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032420"(stereocilium)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|rcsb pdb:2VAC|rcsb pdb:2W0I|reactome:R-HSA-9662360|reactome:R-HSA-9662361 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:qWz7EmcCrpyHRA+wdEsiONY16zA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q12792 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1056675|uniprotkb:Q6NUK9|uniprotkb:A8K5A8|uniprotkb:Q59G07|uniprotkb:Q5U0B1|uniprotkb:Q6FHJ1|uniprotkb:Q6FHL6|uniprotkb:Q86XL6|uniprotkb:Q8TCD3|ensembl:ENSP00000378886|uniprotkb:B3KXS6|uniprotkb:B4DLX9 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:twf1_human(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:PTK9(gene name synonym)|uniprotkb:Protein A6(gene name synonym)|uniprotkb:Protein tyrosine kinase 9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000151239(gene)|ensembl:ENST00000395510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030016"(myofibril)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043538"(regulation of actin phosphorylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|mint:Q12792|refseq:NP_001229326.1|refseq:NP_002813.3|rcsb pdb:7CCC|reactome:R-HSA-9013418|reactome:R-HSA-9662360|reactome:R-HSA-9662361 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:5yv7DC8rsBmxmXtzv40wJ/U154c9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P09493-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11099611|ensembl:ENSP00000351022 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p09493-3(display_long)|uniprotkb:TPM1(gene name)|psi-mi:TPM1(display_short)|uniprotkb:Alpha-tropomyosin(gene name synonym)|uniprotkb:C15orf13(gene name synonym)|uniprotkb:TMSA(gene name synonym)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Fibroblast(isoform synonym)|uniprotkb:TM3(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000140416(gene)|ensembl:ENST00000358278(transcript)|intact:EBI-351158(isoform-parent) - - isoform-comment:Contains a N6-acetyllysine at position 213. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:H/jK3i0BU3aFtVWcIz3xIyR/LyE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O96008 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60784-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-12117154|ensembl:ENSP00000413697 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o60784-2(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000100284(gene)|ensembl:ENST00000411850(transcript)|intact:EBI-74634(isoform-parent)|uniprotkb:O60784-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pSyf40hg3apXj2tU4sB2WBfZSq09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UPQ9-1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10968878|ensembl:ENSP00000338371 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9upq9-1(display_long)|uniprotkb:TNRC6B(gene name)|psi-mi:TNRC6B(display_short)|uniprotkb:KIAA1093(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-947158(isoform-parent)|ensembl:ENSG00000100354(gene)|ensembl:ENST00000335727(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:vkbXMvgP25UMQ2VuIPY1SCh0R6o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8NDV7-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400164 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q8ndv7-2(display_long)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 uniprotkb:Q8NDV7(isoform-parent)|intact:EBI-2269715(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:DRHjw+1A33/o4EQQOYtNz+hpaaE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NYL9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352614|ensembl:ENSP00000308753|uniprotkb:Q9NT43|uniprotkb:Q9NZR0|uniprotkb:B2R6G7 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tmod3_human(display_long)|uniprotkb:TMOD3(gene name)|psi-mi:TMOD3(display_short)|uniprotkb:Ubiquitous tropomodulin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000138594(gene)|ensembl:ENST00000308580(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|refseq:NP_055362.1|go:"GO:0048821"(erythrocyte development)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR004934(Tropomodulin)|interpro:IPR030133|interpro:IPR032675|mint:Q9NYL9|reactome:R-HSA-390522|reactome:R-HSA-9013418|reactome:R-HSA-9696264|refseq:XP_016877576.1|refseq:XP_016877577.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:crEfCAAepSPAE8ByBpD4Sr14P5I9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P28289 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2659631|uniprotkb:B2RB77|uniprotkb:Q5T7W3|uniprotkb:Q9BUF1|ensembl:ENSP00000259365|ensembl:ENSP00000378637|intact:EBI-10965302 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tmod1_human(display_long)|uniprotkb:Erythrocyte tropomodulin(gene name synonym)|uniprotkb:D9S57E(gene name synonym)|uniprotkb:TMOD(gene name synonym)|uniprotkb:TMOD1(gene name)|psi-mi:TMOD1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001159588.1|refseq:NP_003266.1|ensembl:ENST00000259365(transcript)|ensembl:ENST00000395211(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0070307"(lens fiber cell development)|interpro:IPR004934(Tropomodulin)|interpro:IPR030135|interpro:IPR032675|mint:P28289|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4Z8G|rcsb pdb:4Z94|reactome:R-HSA-390522|ensembl:ENSG00000136842(gene) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:xbmnoh2E0cuP4ZYmnhlOo8QDnHw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BTV4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q3ZCQ8-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400236|ensembl:ENSP00000445806 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q3zcq8-2(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name)|uniprotkb:Tim50a(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000105197(gene)|ensembl:ENST00000544017(transcript)|intact:EBI-355175(isoform-parent)|uniprotkb:Q3ZCQ8-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:mwlscSBnVTNN0b4IwPS7EYGTS7Q9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13263-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400228|ensembl:ENSP00000342232 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q13263-2(display_long)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000130726(gene)|ensembl:ENST00000341753(transcript)|intact:EBI-78139(isoform-parent)|uniprotkb:Q13263-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:tt0BfVCqApCCNgfFUpPdQ+16HQI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q86W42-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400221|ensembl:ENSP00000253952 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q86w42-3(display_long)|uniprotkb:Functional spliceosome-associated protein 35(gene name synonym)|uniprotkb:WD repeat-containing protein 58(gene name synonym)|uniprotkb:THOC6(gene name)|psi-mi:THOC6(display_short)|uniprotkb:WDR58(gene name synonym)|uniprotkb:PSEC0006(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000131652(gene)|ensembl:ENST00000253952(transcript)|intact:EBI-2880668(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:sfK4357gCM67iFIp/pEiavNvvNg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P24752 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1051459|uniprotkb:B2R6H1|uniprotkb:G3XAB4|uniprotkb:Q96FG8|ensembl:ENSP00000265838 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:thil_human(display_long)|uniprotkb:Acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:T2(gene name synonym)|uniprotkb:ACAT1(gene name)|psi-mi:ACAT1(display_short)|uniprotkb:ACAT(gene name synonym)|uniprotkb:MAT(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000010.1|ensembl:ENSG00000075239(gene)|ensembl:ENST00000265838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007420"(brain development)|go:"GO:0009725"(response to hormone)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016453"(C-acetyltransferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046356"(acetyl-CoA catabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072229"(metanephric proximal convoluted tubule development)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1902224"(ketone body metabolic process)|go:"GO:1902860"(propionyl-CoA biosynthetic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|rcsb pdb:2F2S|rcsb pdb:2IB7|rcsb pdb:2IB8|rcsb pdb:2IB9|rcsb pdb:2IBU|rcsb pdb:2IBW|rcsb pdb:2IBY|reactome:R-HSA-70895|reactome:R-HSA-77108|reactome:R-HSA-77111 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:UYAY+kDdcJqx/hrDFoXH9rgtm/E9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P09110 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3926709|ensembl:ENSP00000333664|uniprotkb:G5E935|uniprotkb:Q96CA6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:thik_human(display_long)|uniprotkb:ACAA1(gene name)|psi-mi:ACAA1(display_short)|uniprotkb:ACAA(gene name synonym)|uniprotkb:PTHIO(gene name synonym)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Peroxisomal 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:Acetyl-CoA C-myristoyltransferase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001123882.1|refseq:NP_001598.1|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005777"(peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0008775"(acetate CoA-transferase activity)|go:"GO:0010124"(phenylacetate catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016401"(palmitoyl-CoA oxidase activity)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|rcsb pdb:2IIK|reactome:R-HSA-2046106|reactome:R-HSA-390247|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9033500|ensembl:ENSG00000060971(gene)|ensembl:ENST00000333167(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005576"(extracellular region) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:yWp9R9bAzdied8kfDD+qVrY8Slk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NWX6 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-746510|uniprotkb:Q53G12|uniprotkb:Q7L5R3|uniprotkb:Q9H0S2|uniprotkb:D3DQJ5|ensembl:ENSP00000231198 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:thg1_human(display_long)|uniprotkb:Induced in high glucose-1(gene name synonym)|uniprotkb:tRNA-histidine guanylyltransferase(gene name synonym)|uniprotkb:Interphase cytoplasmic foci protein 45(gene name synonym)|uniprotkb:THG1L(gene name)|psi-mi:THG1L(display_short)|uniprotkb:ICF45(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001304753.1|refseq:NP_001304754.1|refseq:NP_001304755.1|refseq:NP_060342.2|ensembl:ENSG00000113272(gene)|ensembl:ENST00000231198(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008033"(tRNA processing)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008193"(tRNA guanylyltransferase activity)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:1990046"(stress-induced mitochondrial fusion)|go:"GO:1990234"(transferase complex)|interpro:IPR007537(tRNAHis guanylyltransferase)|interpro:IPR024956|interpro:IPR025845|interpro:IPR038469|rcsb pdb:3OTB|rcsb pdb:3OTC|rcsb pdb:3OTD|rcsb pdb:3OTE|rcsb pdb:7CV1|reactome:R-HSA-6782315|dip:DIP-59479N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:P1Q3muoqX06qZw9Xu0Gz5f8ALv49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P02786 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355727|uniprotkb:Q59G55|uniprotkb:Q9UCN0|uniprotkb:Q9UCU5|uniprotkb:Q9UDF9|uniprotkb:Q9UK21|uniprotkb:Q1HE24|uniprotkb:D3DXB0|ensembl:ENSP00000353224|ensembl:ENSP00000376197 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tfr1_human(display_long)|uniprotkb:TFRC(gene name)|psi-mi:TFRC(display_short)|uniprotkb:T9(gene name synonym)|uniprotkb:p90(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001121620.1|refseq:NP_003225.2|refseq:NP_001300894.1|refseq:NP_001300895.1|ensembl:ENSG00000072274(gene)|ensembl:ENST00000360110(transcript)|ensembl:ENST00000392396(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:P02786|rcsb pdb:1CX8|rcsb pdb:1DE4|rcsb pdb:1SUV|rcsb pdb:2NSU|rcsb pdb:3KAS|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:3S9N|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6OKD|rcsb pdb:6W3H|rcsb pdb:6WRV|rcsb pdb:6WRW|rcsb pdb:6WRX|rcsb pdb:6Y76|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-917977|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-2736N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:TWJEaKElrOrDMMqSefG5icrTbIU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92734 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P55072 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P40227 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P50990 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P49368-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400214|ensembl:ENSP00000357242 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p49368-2(display_long)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000163468(gene)|ensembl:ENST00000368259(transcript)|intact:EBI-356673(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:+mD3wrymt6JhaQAo6bc1BrpigQc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P48643 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13428-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400208|ensembl:ENSP00000325223 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q13428-2(display_long)|uniprotkb:Treacher Collins syndrome protein(gene name synonym)|uniprotkb:TCOF1(gene name)|psi-mi:TCOF1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000070814(gene)|ensembl:ENST00000323668(transcript)|intact:EBI-396105(isoform-parent)|uniprotkb:Q13428-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Xloqh5KIaPHm2QVo85SfRMdC2HU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P23193 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2608271|uniprotkb:A6NF25|uniprotkb:A8K339|uniprotkb:Q15563|uniprotkb:Q6FG87|ensembl:ENSP00000428426 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tcea1_human(display_long)|uniprotkb:TCEA1(gene name)|psi-mi:TCEA1(display_short)|uniprotkb:GTF2S(gene name synonym)|uniprotkb:TFIIS(gene name synonym)|uniprotkb:Transcription elongation factor S-II protein 1(gene name synonym)|uniprotkb:Transcription elongation factor TFIIS.o(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006747.1|refseq:NP_958845.1|ensembl:ENSG00000187735(gene)|ensembl:ENST00000521604(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901919"(positive regulation of exoribonuclease activity)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR006289(Transcription elongation factor, TFIIS)|interpro:IPR017923|interpro:IPR035100|interpro:IPR035441|interpro:IPR036575|mint:P23193|reactome:R-HSA-167243|reactome:R-HSA-167246|rcsb pdb:1TFI|reactome:R-HSA-167287|rcsb pdb:3NDQ|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:6O9L|reactome:R-HSA-112382|reactome:R-HSA-167290|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-48480N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:88QvzePEd32tHYxrij2EoOYkaLk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y4P3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2513719|ensembl:ENSP00000307260|uniprotkb:Q9UQE2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tbl2_human(display_long)|uniprotkb:TBL2(gene name)|psi-mi:TBL2(display_short)|uniprotkb:WBSCR13(gene name synonym)|uniprotkb:WS beta-transducin repeats protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 13 protein(gene name synonym)|uniprotkb:UNQ563/PRO1125(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000106638(gene)|ensembl:ENST00000305632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR042410|mint:Q9Y4P3|refseq:NP_036585.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:K0mFwM08LEIAWO/zg4Irplaq9oM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BZK7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-765729|uniprotkb:Q14DC3|uniprotkb:Q9H2I1|uniprotkb:Q9H9A1|uniprotkb:D3DNQ9|ensembl:ENSP00000263964|ensembl:ENSP00000387849|ensembl:ENSP00000405574|ensembl:ENSP00000413251|ensembl:ENSP00000501274 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tbl1r_human(display_long)|uniprotkb:Transducin beta-like 1X-related protein 1(gene name synonym)|uniprotkb:Nuclear receptor corepressor/HDAC3 complex subunit TBLR1(gene name synonym)|uniprotkb:TBL1-related protein 1(gene name synonym)|uniprotkb:TBL1XR1(gene name)|psi-mi:TBL1XR1(display_short)|uniprotkb:IRA1(gene name synonym)|uniprotkb:TBLR1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_078941.2|refseq:XP_011511443.1|refseq:XP_011511444.1|refseq:XP_011511445.1|refseq:NP_001308123.1|refseq:NP_001308124.1|refseq:NP_001308122.1|refseq:XP_005247832.1|refseq:XP_006713809.1|refseq:XP_016862674.1|dip:DIP-34582N|ensembl:ENSG00000177565(gene)|ensembl:ENST00000422442(transcript)|ensembl:ENST00000352800(transcript)|ensembl:ENST00000430069(transcript)|ensembl:ENST00000457928(transcript)|ensembl:ENST00000673974(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9BZK7|rcsb pdb:4LG9|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Sr6jJZT7jdfR/ps1xK1ySq9/TuI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BYX2-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400199|ensembl:ENSP00000364207 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9byx2-2(display_long)|uniprotkb:Armus(gene name synonym)|uniprotkb:Prostate antigen recognized and identified by SEREX 1(gene name synonym)|uniprotkb:TBC1D2(gene name)|psi-mi:TBC1D2(display_short)|uniprotkb:PARIS1(gene name synonym)|uniprotkb:PP8997(gene name synonym)|uniprotkb:TBC1D2A(gene name synonym)|uniprotkb:PARIS-1(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-8994876(isoform-parent)|ensembl:ENSG00000095383(gene)|ensembl:ENST00000375066(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/qWSg0sgxiplhGEMtYJU3plx5ww9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60343-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400190|ensembl:ENSP00000366852 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o60343-2(display_long)|uniprotkb:Akt substrate of 160 kDa(gene name synonym)|uniprotkb:TBC1D4(gene name)|psi-mi:TBC1D4(display_short)|uniprotkb:AS160(gene name synonym)|uniprotkb:KIAA0603(gene name synonym)|uniprotkb:AS160_tv2(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-522028(isoform-parent)|uniprotkb:O60343-2(isoform-parent)|ensembl:ENSG00000136111(gene)|ensembl:ENST00000377625(transcript) - - isoform-comment:Contains a phosphoserine at position 666. Contains a phosphoserine at position 672. Contains a phosphoserine at position 678. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:BTHvGVuBrOv3FDQaZRfAbaigyW89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P68363 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H2D6-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400179 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9h2d6-2(display_long)|uniprotkb:Protein Tara(gene name synonym)|uniprotkb:Trio-associated repeat on actin(gene name synonym)|uniprotkb:HRIHFB2122(orf name)|uniprotkb:Long isoform(isoform synonym)|uniprotkb:TRIOBP(gene name)|psi-mi:TRIOBP(display_short)|uniprotkb:KIAA1662(gene name synonym)|uniprotkb:TARA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-715619(isoform-parent)|uniprotkb:Q9H2D6-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:nd4eLNEc1Aoqv9hALefqUZuV4mA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8WXE9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-539742|uniprotkb:Q6NT47|uniprotkb:Q96RI7|uniprotkb:Q96RU6|uniprotkb:Q17R24|uniprotkb:G3V2T7|uniprotkb:Q59H11|intact:EBI-28967360 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ston2_human(display_long)|uniprotkb:Stoned B(gene name synonym)|uniprotkb:STON2(gene name)|psi-mi:STON2(display_short)|uniprotkb:STNB(gene name synonym)|uniprotkb:STN2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 interpro:IPR017110(Stonin)|ensembl:ENST00000555447|ensembl:ENSP00000450857|ensembl:ENSG00000140022|ensembl:ENST00000614646|ensembl:ENSP00000477736|interpro:IPR028565|refseq:NP_149095.2|interpro:IPR012320(Stonin homology)|interpro:IPR022699|interpro:IPR036168|interpro:IPR031228|refseq:NP_001243359.1|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|rcsb pdb:2JXC|mint:Q8WXE9 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:AtPNlh4TC/kL9DnGQJqv1BVwQCM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UJZ1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1044428|ensembl:ENSP00000348886|uniprotkb:O60376|uniprotkb:Q53G29|uniprotkb:Q96FY2|uniprotkb:Q9P042|uniprotkb:D3DRN3|uniprotkb:B4E1K7 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:stml2_human(display_long)|uniprotkb:EPB72-like protein 2(gene name synonym)|uniprotkb:STOML2(gene name)|psi-mi:STOML2(display_short)|uniprotkb:SLP2(gene name synonym)|uniprotkb:HSPC108(orf name)|uniprotkb:Paraprotein target 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000165283(gene)|ensembl:ENST00000356493(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010876"(lipid localization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051020"(GTPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1900210"(positive regulation of cardiolipin metabolic process)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1990046"(stress-induced mitochondrial fusion)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR032435|interpro:IPR036013|mint:Q9UJZ1|reactome:R-HSA-8949664|refseq:NP_001273960.1|refseq:NP_038470.1|refseq:NP_001273961.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:VH6uT4ShPg3IpPHbQtaSVXjZAYg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P43307 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-714168|uniprotkb:A8K685|uniprotkb:Q9TNQ8|uniprotkb:Q53GX2|uniprotkb:Q53H19|uniprotkb:Q5TAM3|uniprotkb:Q6IB43|uniprotkb:Q8NBH9|uniprotkb:Q96IA2|uniprotkb:Q9UN49|ensembl:ENSP00000244763 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ssra_human(display_long)|uniprotkb:Signal sequence receptor subunit alpha(gene name synonym)|uniprotkb:SSR1(gene name)|psi-mi:SSR1(display_short)|uniprotkb:TRAPA(gene name synonym)|uniprotkb:PSEC0262(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003135.2|ensembl:ENSG00000124783(gene)|ensembl:ENST00000244763(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005595("Translocon-associated protein (TRAP), alpha subunit")|mint:P43307|reactome:R-HSA-1799339|reactome:R-HSA-381038|refseq:NP_001278937.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:OhI1z1wbH8LEZaiv+OLChzMvT+A9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BXP5-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-5280046|ensembl:ENSP00000478341 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9bxp5-2(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ARS2(gene name synonym)|uniprotkb:ASR2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000087087(gene)|ensembl:ENST00000618262(transcript)|intact:EBI-712721(isoform-parent)|uniprotkb:Q9BXP5-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:yQ+LWfp4S7IvSa3kLE+B8ACTs8Q9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UQ35 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1050142|uniprotkb:A6NKB9|uniprotkb:Q9UHA8|uniprotkb:Q9UQ36|uniprotkb:Q9UQ37|uniprotkb:Q9UQ38|uniprotkb:Q9UQ40|uniprotkb:O15038|uniprotkb:O94803|uniprotkb:Q6NSL3|uniprotkb:Q6PIM3|uniprotkb:Q6PK40|uniprotkb:Q8IW17|uniprotkb:Q96GY7|uniprotkb:Q9P0G1|uniprotkb:D3DU97|ensembl:ENSP00000301740 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:srrm2_human(display_long)|uniprotkb:Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa(gene name synonym)|uniprotkb:Splicing coactivator subunit SRm300(gene name synonym)|uniprotkb:300 kDa nuclear matrix antigen(gene name synonym)|uniprotkb:SRRM2(gene name)|psi-mi:SRRM2(display_short)|uniprotkb:KIAA0324(gene name synonym)|uniprotkb:SRL300(gene name synonym)|uniprotkb:SRM300(gene name synonym)|uniprotkb:HSPC075(orf name)|uniprotkb:Tax-responsive enhancer element-binding protein 803(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_057417.3|ensembl:ENSG00000167978(gene)|ensembl:ENST00000301740(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945|mint:Q9UQ35|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7DVQ|reactome:R-HSA-72163 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3yyPAOaCzKSCEg5guJSbq0MWrHI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14247 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P12931-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400094|ensembl:ENSP00000362659 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p12931-2(display_long)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)|uniprotkb:pp60c-src(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000197122(gene)|ensembl:ENST00000373558(transcript)|intact:EBI-621482(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:WFJsHrjw9e+pT0U7naGREuKgJVU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O94875 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-311323|intact:EBI-747334|uniprotkb:B7Z1G5|uniprotkb:C9JKV9|uniprotkb:G3XAI0|intact:EBI-2804177|uniprotkb:A6NEK9|uniprotkb:O60592|uniprotkb:O60593|uniprotkb:Q96EX0|uniprotkb:D3DP62|uniprotkb:D3DP63|intact:EBI-28977791|ensembl:ENSP00000284776|uniprotkb:B7Z3X6|uniprotkb:E9PAS5|uniprotkb:E9PAW4|uniprotkb:B3KPQ7|uniprotkb:H7BXR4|uniprotkb:J3KNZ5|intact:EBI-10983198|intact:EBI-10965282 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:srbs2_human(display_long)|uniprotkb:SORBS2(gene name)|psi-mi:SORBS2(display_short)|uniprotkb:ARGBP2(gene name synonym)|uniprotkb:KIAA0777(gene name synonym)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Sorbin(gene name synonym)|uniprotkb:Arg-binding protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000284776|ensembl:ENST00000319471|ensembl:ENSP00000322182|ensembl:ENST00000355634|ensembl:ENSP00000347852|ensembl:ENST00000393528|ensembl:ENSP00000377162|ensembl:ENST00000418609|ensembl:ENSP00000397482|ensembl:ENST00000437304|ensembl:ENSP00000396008|ensembl:ENST00000448662|ensembl:ENSP00000409158|ensembl:ENST00000449407|ensembl:ENSP00000397262|ensembl:ENSG00000154556(gene)|ensembl:ENST00000284776(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028506|interpro:IPR036028|mint:O94875|rcsb pdb:5VEI|refseq:NP_001139142.1|refseq:NP_001139144.1|refseq:NP_001139145.1|refseq:NP_066547.1|refseq:NP_001139146.1|refseq:NP_001139143.1|refseq:NP_001257700.1|refseq:NP_003594.3|refseq:XP_005263369.1|refseq:XP_006714453.1|refseq:XP_016864260.1|dip:DIP-31634N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ficlNf23am8NpwQVRUKXeVUJTsQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BX66-10 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400106|ensembl:ENSP00000360295 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9bx66-10(display_long)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000095637(gene)|ensembl:ENST00000371249(transcript)|intact:EBI-433642(isoform-parent) - - isoform-comment:No experimental confirmation available. Contains a phosphoserine at position 478. Contains a phosphoserine at position 735. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/lLkxqMZEzXGzL0WNK+ZK51+WDc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13501 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13813 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q01082 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P49903 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-714091|uniprotkb:D3DRS9|uniprotkb:D6PSQ9|uniprotkb:Q9BVT4|uniprotkb:Q5T5U8|intact:EBI-1045366|ensembl:ENSP00000367893|uniprotkb:B4DWK0|uniprotkb:Q5T5U9 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sps1_human(display_long)|uniprotkb:Selenophosphate synthase 1(gene name synonym)|uniprotkb:Selenium donor protein 1(gene name synonym)|uniprotkb:SEPHS1(gene name)|psi-mi:SEPHS1(display_short)|uniprotkb:SELD(gene name synonym)|uniprotkb:SPS(gene name synonym)|uniprotkb:SPS1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001182531.1|refseq:NP_001182533.1|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR004536(Selenide water dikinase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR016188(PurM, N-terminal-like)|interpro:IPR036676|interpro:IPR036921|mint:P49903|rcsb pdb:3FD5|rcsb pdb:3FD6|ensembl:ENSG00000086475(gene)|ensembl:ENST00000327347(transcript)|go:"GO:0004756"(selenide, water dikinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016260"(selenocysteine biosynthetic process)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|refseq:NP_036379.2|refseq:XP_016871431.1|refseq:XP_016871432.1|refseq:XP_016871434.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:lofaL1G9IpLjOna+cSeMvE0kQ+A9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43278 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-953990|ensembl:ENSP00000342098|uniprotkb:Q7Z7D2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:spit1_human(display_long)|uniprotkb:Hepatocyte growth factor activator inhibitor type 1(gene name synonym)|uniprotkb:SPINT1(gene name)|psi-mi:SPINT1(display_short)|uniprotkb:HAI1(gene name synonym)|uniprotkb:UNQ223/PRO256(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000166145(gene)|ensembl:ENST00000344051(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR042482|rcsb pdb:1YC0|rcsb pdb:2MSX|rcsb pdb:4ISL|rcsb pdb:4ISN|rcsb pdb:4ISO|rcsb pdb:5EZD|rcsb pdb:5H7V|reactome:R-HSA-6806942|reactome:R-HSA-8852405|interpro:IPR011106(Seven cysteines, N-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013980(Seven cysteines)|interpro:IPR020901|interpro:IPR023415|interpro:IPR036055|interpro:IPR036880|refseq:NP_001027539.1|refseq:NP_003701.1|refseq:NP_857593.1|refseq:XP_006720720.1|dip:DIP-37949N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:feHnyLQq6rOSG2IW9dCGVBkcurg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y5X1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-77848|ensembl:ENSP00000376024|ensembl:ENSP00000506326|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000130340(gene)|ensembl:ENST00000392185(transcript)|ensembl:ENST00000679814(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028644|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_057308.1|dip:DIP-30997N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13573 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-632715|uniprotkb:Q13483|uniprotkb:Q32N03|uniprotkb:Q5D0D6|uniprotkb:A8K8A9|ensembl:ENSP00000261531 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:snw1_human(display_long)|uniprotkb:Nuclear protein SkiP(gene name synonym)|uniprotkb:Ski-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor coactivator NCoA-62(gene name synonym)|uniprotkb:SKIIP(gene name synonym)|uniprotkb:SKIP(gene name synonym)|uniprotkb:SNW1(gene name)|psi-mi:SNW1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_036377.1|ensembl:ENSG00000100603(gene)|ensembl:ENST00000261531(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048385"(regulation of retinoic acid receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0070564"(positive regulation of vitamin D receptor signaling pathway)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR004015(SKIP/SNW)|interpro:IPR017862|mint:Q13573|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-72163|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|dip:DIP-34800N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:DwdpE5FIS2KfI0GOFt9IbAvjm/Y9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q99747 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3221833|uniprotkb:B4DFC9|ensembl:ENSP00000324628|uniprotkb:Q9BUV1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:snag_human(display_long)|uniprotkb:NAPG(gene name)|psi-mi:NAPG(display_short)|uniprotkb:SNAPG(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein gamma(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000134265(gene)|ensembl:ENST00000322897(transcript)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0045202"(synapse)|go:"GO:0050821"(protein stabilization)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q99747|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:XP_011524058.1|refseq:NP_003817.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:QbHDxqDWn6/UYiMIOMiKfx5eCFg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P54920 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-749652|uniprotkb:Q96IK3|uniprotkb:Q9BVJ3|uniprotkb:A8K879|ensembl:ENSP00000263354 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:snaa_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:NAPA(gene name)|psi-mi:NAPA(display_short)|uniprotkb:SNAPA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003818.2|ensembl:ENSG00000105402(gene)|ensembl:ENST00000263354(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016020"(membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-HSA-204005|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RHbBvhRSSaakY4HPkl3Y9ggkiPk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P53814-5 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11100581|ensembl:ENSP00000329532 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p53814-5(display_long)|uniprotkb:SMTN(gene name)|psi-mi:SMTN(display_short)|uniprotkb:SMSMO(gene name synonym)|uniprotkb:L2(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000183963(gene)|intact:EBI-1199956(isoform-parent)|ensembl:ENST00000333137(transcript)|uniprotkb:P53814-5(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:AKoICW9OuTX6YNlstWfYKw0KBzY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q16637 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14493 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2696402|uniprotkb:B3KRJ5|ensembl:ENSP00000417686 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:slbp_human(display_long)|uniprotkb:SLBP(gene name)|psi-mi:SLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Histone stem-loop-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001293003.1|refseq:NP_001293004.1|refseq:NP_006518.1|ensembl:ENSG00000163950(gene)|ensembl:ENST00000489418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR026502|interpro:IPR029344|interpro:IPR038294|mint:Q14493|rcsb pdb:2KJM|rcsb pdb:4L8R|rcsb pdb:4QOZ|reactome:R-HSA-159230|reactome:R-HSA-73856|reactome:R-HSA-77588|dip:DIP-57045N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Rt3HJRsfQ5SAgjMsloMR6H7Emho9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60292 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2559690|uniprotkb:Q2TV87|intact:EBI-28973263|ensembl:ENSP00000222345 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:si1l3_human(display_long)|uniprotkb:SIPA1L3(gene name)|psi-mi:SIPA1L3(display_short)|uniprotkb:KIAA0545(gene name synonym)|uniprotkb:SPAL3(gene name synonym)|uniprotkb:SPA-1-like protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000222345|refseq:XP_011524959.1|refseq:NP_055888.1|ensembl:ENSG00000105738(gene)|ensembl:ENST00000222345(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001725"(stress fiber)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0045177"(apical part of cell)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR031204|interpro:IPR035974|interpro:IPR036034|mint:O60292|go:"GO:0061689"(tricellular tight junction)|refseq:XP_005258728.1|refseq:XP_016882006.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:IzfxQ79AL5Y4lieFeMcvEYmPJu49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8TBC3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-724292|uniprotkb:Q8N2I6|uniprotkb:Q96IB8|uniprotkb:Q8WY93|intact:EBI-28987662|ensembl:ENSP00000291842 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:shkb1_human(display_long)|uniprotkb:SHKBP1(gene name)|psi-mi:SHKBP1(display_short)|uniprotkb:SB1(gene name synonym)|uniprotkb:SETA-binding protein 1(gene name synonym)|uniprotkb:PP203(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_612401.2|interpro:IPR001680(WD40 repeat)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|ensembl:ENSG00000160410(gene)|ensembl:ENST00000291842(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:4CRH|reactome:R-HSA-9013148|ensembl:ENSP00000291842 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:2cIBkgod4mRxgPSslubgbqyJtFk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96B97 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-346595|uniprotkb:Q8IWX6|uniprotkb:Q8IX98|uniprotkb:Q96RN4|uniprotkb:Q9NYR0|uniprotkb:B7Z1D5|uniprotkb:Q5JPT4|uniprotkb:Q5JPT5|ensembl:ENSP00000380921 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sh3k1_human(display_long)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:CD2-binding protein 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001019837.1|refseq:NP_114098.1|refseq:NP_001171889.1|refseq:XP_016884958.1|dip:DIP-31803N|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR035770|interpro:IPR035771|interpro:IPR035772|interpro:IPR036028|mint:Q96B97|rcsb pdb:2BZ8|rcsb pdb:2K6D|rcsb pdb:2K9G|rcsb pdb:2N64|rcsb pdb:2O2O|rcsb pdb:2YDL|rcsb pdb:5ABS|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866376|reactome:R-HSA-8875360|reactome:R-HSA-983695|go:"GO:0007015"(actin filament organization) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q99961 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|dip:DIP-29452N|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360 - - crc64:6E5BE978BC955077 figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43765 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q99729-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10980488|ensembl:ENSP00000348093|ensembl:ENSP00000427465 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q99729-3(display_long)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRPAB(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000197451(gene)|ensembl:ENST00000355836(transcript)|ensembl:ENST00000506259(transcript)|intact:EBI-1044873(isoform-parent) - - isoform-comment:Contains a omega-N-methylarginine at position 250. Contains a omega-N-methylarginine at position 253. Contains a phosphoserine at position 255. Contains a N6-acetyllysine at position 271. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:vdzrfLpXLW88X5gmR/4mVDhWU489606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P51991 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P22626 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P09651-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352677|ensembl:ENSP00000446486|ensembl:ENSP00000448617|ensembl:ENSP00000449913 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p09651-2(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-352662(roa1_human)|ensembl:ENSG00000135486(gene)|ensembl:ENST00000546500(transcript)|ensembl:ENST00000547566(transcript)|ensembl:ENST00000550482(transcript)|uniprotkb:P09651-2(isoform-parent) - - isoform-comment:Is twenty times more abundant than isoform A1-B. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Co5hW3ZlIoa2k56GA2/9RJBNguI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13151 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P05388 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q02878 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P46777 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P36578 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-348313|ensembl:ENSP00000311430|uniprotkb:P39029|uniprotkb:Q4VBR0|uniprotkb:Q969Z9|uniprotkb:A8K502 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rl4_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:RPL1(gene name synonym)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000174444(gene)|ensembl:ENST00000307961(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR025755|mint:P36578|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|interpro:IPR023574|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OM0|refseq:NP_000959.2|dip:DIP-27559N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:34il/jyrW0Dqj0eA8GBFgUk05XU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P13489 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96D71-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10284512|ensembl:ENSP00000258062 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96d71-3(display_long)|uniprotkb:REPS1(gene name)|psi-mi:REPS1(display_short)|uniprotkb:RalBP1-interacting protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1171195(isoform-parent)|ensembl:ENSG00000135597(gene)|ensembl:ENST00000258062(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Tum2NBs1Lu+88po9J8KoJtK2Ylw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15293 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-948278|ensembl:ENSP00000054950|uniprotkb:D3DR00|uniprotkb:B7Z1M1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rcn1_human(display_long)|uniprotkb:RCN1(gene name)|psi-mi:RCN1(display_short)|uniprotkb:RCN(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 reactome:R-HSA-8957275|reactome:R-HSA-381426|ensembl:ENSG00000049449(gene)|ensembl:ENST00000054950(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q15293|refseq:NP_002892.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ynhvrXX2fQ7Dn1LT+mp2PKm0bc89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15311 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-749285|uniprotkb:D3DUI0|ensembl:ENSP00000019317|ensembl:ENSP00000372924 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rbp1_human(display_long)|uniprotkb:Ral-interacting protein 1(gene name synonym)|uniprotkb:76 kDa Ral-interacting protein(gene name synonym)|uniprotkb:Dinitrophenyl S-glutathione ATPase(gene name synonym)|uniprotkb:RALBP1(gene name)|psi-mi:RALBP1(display_short)|uniprotkb:RLIP1(gene name synonym)|uniprotkb:RLIP76(gene name synonym)|uniprotkb:RLIP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006779.1|ensembl:ENSG00000017797(gene)|ensembl:ENST00000019317(transcript)|ensembl:ENST00000383432(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015431"(ABC-type glutathione S-conjugate transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0055085"(transmembrane transport)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1900753"(doxorubicin transport)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR039767|mint:Q15311|rcsb pdb:2KWH|rcsb pdb:2KWI|rcsb pdb:2MBG|rcsb pdb:6ZQT|rcsb pdb:6ZRN|reactome:R-HSA-9013148|reactome:R-HSA-9013149 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:6u1yy+UdGWJbJ9SiItSAp+CqeVk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BWF3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2856454|uniprotkb:B3KUN0|uniprotkb:Q8WU85|uniprotkb:Q6P1P2|uniprotkb:O02916|uniprotkb:Q4VC48|uniprotkb:B4E1U0|uniprotkb:E7EQS3|ensembl:ENSP00000309166|ensembl:ENSP00000386561|ensembl:ENSP00000386894 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rbm4_human(display_long)|uniprotkb:RBM4(gene name)|psi-mi:RBM4(display_short)|uniprotkb:RBM4A(gene name synonym)|uniprotkb:Lark homolog(gene name synonym)|uniprotkb:RNA-binding motif protein 4(gene name synonym)|uniprotkb:RNA-binding motif protein 4a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001185772.1|refseq:NP_002887.2|refseq:NP_001185773.1|dip:DIP-44199N|ensembl:ENSG00000173933(gene)|ensembl:ENST00000310092(transcript)|ensembl:ENST00000408993(transcript)|ensembl:ENST00000409406(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002190"(cap-independent translational initiation)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:0097167"(circadian regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979|mint:Q9BWF3|rcsb pdb:2DNQ|reactome:R-HSA-400253|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:hbW6dv/AEWQz3mWvA2/9n8h/bbA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15291-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400009|ensembl:ENSP00000356132 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q15291-2(display_long)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-592823(isoform-parent)|ensembl:ENSG00000117222(gene)|ensembl:ENST00000367164(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:7YbaQO/KqCd5DQm0w5+756EdTdY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UKM9-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11071394|ensembl:ENSP00000364255 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9ukm9-2(display_long)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)|uniprotkb:Autoantigen p542(gene name synonym)|uniprotkb:HNRPCL2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 2(gene name synonym)|uniprotkb:P542(gene name synonym)|uniprotkb:hnRNP associated with lethal yellow protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-714796(isoform-parent)|ensembl:ENSG00000125970(gene)|ensembl:ENST00000375114(transcript)|uniprotkb:Q9UKM9-2(isoform-parent) - - isoform-comment:Contains a phosphoserine at position 106. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:18uuC6SClaCS9DJCl7XCOgvdgAg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8NFJ5 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2561555|ensembl:ENSP00000014914|uniprotkb:O95357|uniprotkb:B3KV45 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rai3_human(display_long)|uniprotkb:GPRC5A(gene name)|psi-mi:GPRC5A(display_short)|uniprotkb:GPCR5A(gene name synonym)|uniprotkb:RAI3(gene name synonym)|uniprotkb:RAIG1(gene name synonym)|uniprotkb:G-protein coupled receptor family C group 5 member A(gene name synonym)|uniprotkb:Retinoic acid-induced gene 1 protein(gene name synonym)|uniprotkb:Phorbol ester induced gene 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000013588(gene)|ensembl:ENST00000014914(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031982"(vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR017978|refseq:NP_003970.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:34/gAVA1PebkQgzu1veBTClSGcE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9P0K7-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400036|ensembl:ENSP00000427123 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9p0k7-2(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:sNORPEG(isoform synonym)|uniprotkb:RAI14(gene name)|psi-mi:RAI14(display_short)|uniprotkb:KIAA1334(gene name synonym)|uniprotkb:NORPEG(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000039560(gene)|ensembl:ENST00000515799(transcript)|intact:EBI-1023749(isoform-parent)|uniprotkb:Q9P0K7-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:UTZPLHITU3o2XK60xX9Xo3+lFYs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P78406 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-724495|uniprotkb:O15306|uniprotkb:Q3SYL7|uniprotkb:Q5TCH8|uniprotkb:Q6V708|uniprotkb:Q9H100|uniprotkb:Q9NQM6|ensembl:ENSP00000360286|ensembl:ENSP00000379181|ensembl:ENSP00000379182|uniprotkb:A8K882 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rae1l_human(display_long)|uniprotkb:mRNA-associated protein mrnp 41(gene name synonym)|uniprotkb:Rae1 protein homolog(gene name synonym)|uniprotkb:RAE1(gene name)|psi-mi:RAE1(display_short)|uniprotkb:MRNP41(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001015885.1|refseq:NP_003601.1|ensembl:ENSG00000101146(gene)|ensembl:ENST00000371242(transcript)|ensembl:ENST00000395840(transcript)|ensembl:ENST00000395841(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037631|mint:P78406|rcsb pdb:3MMY|rcsb pdb:4OWR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|interpro:IPR019775|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|refseq:XP_011527390.1|refseq:XP_011527391.1|refseq:XP_005260639.2|dip:DIP-41063N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:JK4Y5p3WUcHFXBXyhhqCnDnG49c9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P35241 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:75lzbINdL0deHtiWY7IwioSh5749606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q00577 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1045860|ensembl:ENSP00000332706|ensembl:ENSP00000499133 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pura_human(display_long)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)|uniprotkb:PURA(gene name)|psi-mi:PURA(display_short)|uniprotkb:PUR1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005850.1|ensembl:ENSG00000185129(gene)|ensembl:ENST00000331327(transcript)|ensembl:ENST00000651386(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030500|mint:Q00577 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:4NuTKCFE1X+wdaAs+0Brd8IsFS89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P22234 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P26599-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-350557|ensembl:ENSP00000408096 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p26599-2(display_long)|uniprotkb:PTB2(isoform synonym)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:PTB(gene name synonym)|uniprotkb:57 kDa RNA-binding protein PPTB-1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-350540(ptbp1_human)|ensembl:ENSG00000011304(gene)|ensembl:ENST00000394601(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:BJPhqT+INdKSk3fKPDpao9uoDbY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15008 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P51665 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UNM6 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:iOxE62MMeGx+aqsrir/LukJqeho9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00231 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:BgQKXK7gMMihacRCI+g/pBnRN309606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P62195 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N - - crc64:29C6410C4A85A7F7 figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P62333 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y570-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400028 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9y570-2(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1772895(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:MMIOQopjTybTigOMlvzVL8rG8Sw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P10696 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2557899|uniprotkb:Q96CM1|uniprotkb:A8KAF2|uniprotkb:Q16727|uniprotkb:Q53S81|ensembl:ENSP00000295453 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ppbn_human(display_long)|uniprotkb:ALPG(gene name)|psi-mi:ALPG(display_short)|uniprotkb:ALP-1(gene name synonym)|uniprotkb:ALPPL(gene name synonym)|uniprotkb:ALPPL2(gene name synonym)|uniprotkb:Alkaline phosphatase Nagao isozyme(gene name synonym)|uniprotkb:Alkaline phosphatase, placental-like(gene name synonym)|uniprotkb:Germ cell alkaline phosphatase(gene name synonym)|uniprotkb:Placental alkaline phosphatase-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_112603.2|ensembl:ENSG00000163286(gene)|ensembl:ENST00000295453(transcript)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|reactome:R-HSA-163125 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:7+Mu+FXW0V3WQbaWO0u083e6Jc09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P09923 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1052631|uniprotkb:Q53S80|uniprotkb:Q9UBV5|uniprotkb:Q9UCL2|uniprotkb:B2R7Y4|ensembl:ENSP00000295463 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ppbi_human(display_long)|uniprotkb:ALPI(gene name)|psi-mi:ALPI(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001622.2|ensembl:ENSG00000163295(gene)|ensembl:ENST00000295463(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002020"(protease binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|reactome:R-HSA-1483166|reactome:R-HSA-163125|reactome:R-HSA-8935690 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RVz6SrTgIp87b+FLyMYQuoQDsI49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P62714 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P62140 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P62136 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6S8J3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-4289913|uniprotkb:Q6S8J4|uniprotkb:Q6S8J8|uniprotkb:Q6S8J5|ensembl:ENSP00000439189|ensembl:ENSP00000507284 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:potee_human(display_long)|uniprotkb:POTEE(gene name)|psi-mi:POTEE(display_short)|uniprotkb:A26C1A(gene name synonym)|uniprotkb:POTE2(gene name synonym)|uniprotkb:ANKRD26-like family C member 1A(gene name synonym)|uniprotkb:Prostate, ovary, testis-expressed protein on chromosome 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000188219(gene)|ensembl:ENST00000356920(transcript)|ensembl:ENST00000683005(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129|reactome:R-HSA-9035034|interpro:IPR020902|refseq:NP_001077007.1|refseq:XP_016859650.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:LMuv4bmAG2/uPyH5LR9q+ickvWI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15165-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400023|ensembl:ENSP00000404622 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q15165-3(display_long)|uniprotkb:Aromatic esterase 2(gene name synonym)|uniprotkb:Serum aryldialkylphosphatase 2(gene name synonym)|uniprotkb:PON2(gene name)|psi-mi:PON2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-3909798(isoform-parent)|ensembl:ENSG00000105854(gene)|ensembl:ENST00000433091(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:hwaI7jPXaeirsx1WqPPNX3yCM6I9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P13797 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-698052|uniprotkb:B1AQ09|uniprotkb:Q86YI6|uniprotkb:A8K579|uniprotkb:B4DGB4|uniprotkb:B7Z6M1|ensembl:ENSP00000348163|ensembl:ENSP00000445339 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:plst_human(display_long)|uniprotkb:T-plastin(gene name synonym)|uniprotkb:PLS3(gene name)|psi-mi:PLS3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001129497.1|refseq:NP_005023.2|refseq:XP_011535836.1|refseq:NP_001165806.1|refseq:NP_001269266.1|refseq:NP_001269267.1|ensembl:ENSG00000102024(gene)|ensembl:ENST00000355899(transcript)|ensembl:ENST00000539310(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0032432"(actin filament bundle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060348"(bone development)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|mint:P13797|rcsb pdb:1AOA|rcsb pdb:1WJO - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RWAS8uhDHEtqdDd1gfsqDDyvvsE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14651 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1047196|uniprotkb:D3DNG3|uniprotkb:A8K2Q1|uniprotkb:Q8NEG6|ensembl:ENSP00000336831|ensembl:ENSP00000387890|ensembl:ENSP00000418700 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:plsi_human(display_long)|uniprotkb:Intestine-specific plastin(gene name synonym)|uniprotkb:PLS1(gene name)|psi-mi:PLS1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 interpro:IPR018247|interpro:IPR011992(EF-Hand type)|interpro:IPR030235|interpro:IPR036872|interpro:IPR039959|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001138791.1|refseq:NP_001165783.1|refseq:NP_002661.2|refseq:XP_011511202.1|refseq:XP_011511203.1|refseq:XP_011511205.1|ensembl:ENSG00000120756(gene)|ensembl:ENST00000337777(transcript)|ensembl:ENST00000457734(transcript)|ensembl:ENST00000497002(transcript)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005903"(brush border)|go:"GO:0032420"(stereocilium)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060121"(vestibular receptor cell stereocilium organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990357"(terminal web)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|refseq:XP_006713723.1|refseq:XP_016862115.1|refseq:XP_016862116.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:jDBbZOh8WmNZbAhnOmxcqb6fGvc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60664-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400016|ensembl:ENSP00000465596 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o60664-3(display_long)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:TIP47(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000105355(gene)|ensembl:ENST00000585479(transcript)|intact:EBI-725795(isoform-parent)|uniprotkb:O60664-3(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:S7eZyWlDTIo+kHGab/GC/5lOk1A9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6P4A8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2861204|uniprotkb:Q9BVV3|uniprotkb:Q9H625|uniprotkb:A8K4E9|ensembl:ENSP00000240617 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:plbl1_human(display_long)|uniprotkb:PLBD1(gene name)|psi-mi:PLBD1(display_short)|uniprotkb:LAMA-like protein 1(gene name synonym)|uniprotkb:Lamina ancestor homolog 1(gene name synonym)|uniprotkb:Phospholipase B domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_079105.4|ensembl:ENSG00000121316(gene)|ensembl:ENST00000240617(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0009395"(phospholipid catabolic process)|interpro:IPR007000(Laminin A)|interpro:IPR043040|interpro:IPR043041|interpro:IPR043042|mint:Q6P4A8|reactome:R-HSA-1482788|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1483115 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:6ZbYKlwkiOBkyp3kckZ4QkLCj689606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P14923 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:A1L390 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-4401429|ensembl:ENSP00000247226|uniprotkb:A1L389|uniprotkb:B5MEC9|uniprotkb:O60339|uniprotkb:Q6GMS3|uniprotkb:Q6P4B1|uniprotkb:Q7L3S3|uniprotkb:Q86SW7|uniprotkb:Q8TEF5|uniprotkb:Q96EW6|uniprotkb:Q9BT82|intact:EBI-28970790 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pkhg3_human(display_long)|uniprotkb:PLEKHG3(gene name)|psi-mi:PLEKHG3(display_short)|uniprotkb:KIAA0599(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000126822(gene)|ensembl:ENST00000247226(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035899|interpro:IPR043324|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013408|ensembl:ENSP00000247226|ensembl:ENST00000394691|ensembl:ENSP00000378183|refseq:XP_016876646.1|refseq:NP_001295076.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:+obep09w4klmkB8i13aA5FQW2609606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H307 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-681904|uniprotkb:Q9UQR9|uniprotkb:O60899|uniprotkb:Q53EM7|uniprotkb:Q6P5X4|uniprotkb:Q7KYL1|uniprotkb:Q99738|uniprotkb:Q9UHZ9|uniprotkb:B4DZX8|ensembl:ENSP00000216832 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pinin_human(display_long)|uniprotkb:140 kDa nuclear and cell adhesion-related phosphoprotein(gene name synonym)|uniprotkb:Domain-rich serine protein(gene name synonym)|uniprotkb:Melanoma metastasis clone A protein(gene name synonym)|uniprotkb:Desmosome-associated protein(gene name synonym)|uniprotkb:SR-like protein(gene name synonym)|uniprotkb:Nuclear protein SDK3(gene name synonym)|uniprotkb:PNN(gene name)|psi-mi:PNN(display_short)|uniprotkb:DRS(gene name synonym)|uniprotkb:MEMA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002678.2|dip:DIP-32950N|ensembl:ENSG00000100941(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030057"(desmosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006786(Pinin/SDK/memA protein)|interpro:IPR006787(Pinin/SDK)|interpro:IPR039853|mint:Q9H307|ensembl:ENST00000216832(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:1pAhD0z8tks+HkWaYWkdMmSjk3s9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P54136-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400174 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p54136-2(display_long)|uniprotkb:RARS1(gene name)|psi-mi:RARS1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:RARS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-355482(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:UXrHNte3fgHW8rCgzJeX4MCcNjk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13492-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10983186|ensembl:ENSP00000348718 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q13492-2(display_long)|uniprotkb:CALM(gene name synonym)|uniprotkb:Clathrin assembly lymphoid myeloid leukemia protein(gene name synonym)|uniprotkb:Type II(isoform synonym)|uniprotkb:PICALM(gene name)|psi-mi:PICALM(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000073921(gene)|ensembl:ENST00000356360(transcript)|intact:EBI-2803688(isoform-parent)|uniprotkb:Q13492-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:23MG1xdeDQ2K6tu+lnn7D3Iafmw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P47897 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-347462|uniprotkb:B4DWJ2|ensembl:ENSP00000307567 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:syq_human(display_long)|uniprotkb:QARS1(gene name)|psi-mi:QARS1(display_short)|uniprotkb:Glutaminyl-tRNA synthetase(gene name synonym)|uniprotkb:QARS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005042.1|ensembl:ENSG00000172053(gene)|ensembl:ENST00000306125(transcript)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004514(Glutaminyl-tRNA synthetase, class Ic)|interpro:IPR007638(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 2)|interpro:IPR007639(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 1)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR042558|interpro:IPR042559|mint:P47897|rcsb pdb:4R3Z|rcsb pdb:4YE6|rcsb pdb:4YE8|rcsb pdb:4YE9|reactome:R-HSA-2408522|go:"GO:0006469"(negative regulation of protein kinase activity)|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0007420"(brain development)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001259002.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3Q8LR+aWJJue/ixtD3ZYDpC/D3o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8N3V7-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965260|ensembl:ENSP00000302139 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q8n3v7-2(display_long)|uniprotkb:SYNPO(gene name)|psi-mi:SYNPO(display_short)|uniprotkb:KIAA1029(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000171992(gene)|ensembl:ENST00000307662(transcript)|intact:EBI-352936(isoform-parent) - - isoform-comment:Contains a N-acetylmethionine at position 1. Contains a phosphoserine at position 738. Contains a phosphoserine at position 784. Contains a phosphoserine at position 804. Contains a phosphoserine at position 812. Contains a phosphoserine at position 826. Contains a phosphoserine at position 854. Contains a phosphoserine at position 871. Contains a phosphoserine at position 894. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:53LB2alIgoGX9uXbTHT4EmQwbnQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43426 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2821539|uniprotkb:O43425|uniprotkb:O94984|uniprotkb:Q4KMR1|ensembl:ENSP00000501426 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:synj1_human(display_long)|uniprotkb:SYNJ1(gene name)|psi-mi:SYNJ1(display_short)|uniprotkb:KIAA0910(gene name synonym)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001153774.1|refseq:NP_001153778.1|refseq:NP_003886.3|refseq:NP_982271.2|refseq:XP_016883989.1|ensembl:ENSG00000159082(gene)|ensembl:ENST00000674308(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005874"(microtubule)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034097"(response to cytokine)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0061024"(membrane organization)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:1904980"(positive regulation of endosome organization)|go:"GO:1990175"(EH domain binding)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR034971|interpro:IPR034972|interpro:IPR035979|interpro:IPR036691|mint:O43426|rcsb pdb:1W80|rcsb pdb:2DNR|rcsb pdb:2VJ0|rcsb pdb:7A0V|reactome:R-HSA-1660499|reactome:R-HSA-1855183|reactome:R-HSA-1855204|reactome:R-HSA-8856828 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RA73eMbCn6F7MD0ItxF/V7QbjqM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q99623 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:h4pib54mBeQgOKCe/hib58LM26w9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96ES7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P23246 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P41252 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355303|uniprotkb:Q5TCD0|uniprotkb:Q9H588|uniprotkb:A8KAE9|uniprotkb:Q7Z3T4|ensembl:ENSP00000364794|ensembl:ENSP00000406448|ensembl:ENSP00000507144 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:syic_human(display_long)|uniprotkb:IARS1(gene name)|psi-mi:IARS1(display_short)|uniprotkb:IARS(gene name synonym)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002152.2|refseq:NP_038203.2|ensembl:ENSG00000196305(gene)|ensembl:ENST00000375643(transcript)|ensembl:ENST00000443024(transcript)|ensembl:ENST00000683565(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023586|interpro:IPR033709|mint:P41252|reactome:R-HSA-2408522|reactome:R-HSA-379716 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:maAJX/O1Ryxr5NVFQEWvXNgHXyY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P00558 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000282.1|dip:DIP-33679N|ensembl:ENSG00000102144(gene)|ensembl:ENST00000373316(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O15047 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-540779|uniprotkb:A6NP62|uniprotkb:Q6PIF3|uniprotkb:Q8TAJ6|intact:EBI-28969638|ensembl:ENSP00000262519|ensembl:ENSP00000507683 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:set1a_human(display_long)|uniprotkb:KMT2F(gene name synonym)|uniprotkb:SET domain-containing protein 1A(gene name synonym)|uniprotkb:Set1/Ash2 histone methyltransferase complex subunit SET1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2F(gene name synonym)|uniprotkb:SETD1A(gene name)|psi-mi:SETD1A(display_short)|uniprotkb:KIAA0339(gene name synonym)|uniprotkb:SET1(gene name synonym)|uniprotkb:SET1A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_055527.1|refseq:XP_006721169.1|ensembl:ENSP00000262519|ensembl:ENSP00000507683|reactome:R-HSA-8936459|reactome:R-HSA-3214841|ensembl:ENSG00000099381(gene)|ensembl:ENST00000262519(transcript)|ensembl:ENST00000684162(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034467|interpro:IPR035979|interpro:IPR037841|interpro:IPR044570|mint:O15047|go:"GO:0048188"(Set1C/COMPASS complex)|rcsb pdb:3S8S|rcsb pdb:3UVN|rcsb pdb:4EWR|refseq:XP_005255780.1|refseq:XP_016879398.1|dip:DIP-33494N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:nx0uWEVFas1w2NmuG73lCObAULE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P50454 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P07814 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|ensembl:ENSP00000355890|uniprotkb:B9EGH3 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004437.2|ensembl:ENSG00000136628(gene)|ensembl:ENST00000366923(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|dip:DIP-40825N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43175 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q16181-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10176094 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q16181-2(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-2009373(isoform-parent)|uniprotkb:Q16181-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Sg2BdKxeuOrHclAn8D+OPcMr94Y9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15019-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10983222|ensembl:ENSP00000479861 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q15019-2(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000168385(gene)|ensembl:ENST00000616972(transcript)|intact:EBI-741220(isoform-parent)|uniprotkb:Q15019-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:IIEvYwOdQMIWn9owBqoN8CtLutE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y2Z0-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10768076|ensembl:ENSP00000308067 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9y2z0-2(display_long)|uniprotkb:Protein 40-6-3(gene name synonym)|uniprotkb:Sgt1(gene name synonym)|uniprotkb:Suppressor of G2 allele of SKP1 homolog(gene name synonym)|uniprotkb:SGT1A(isoform synonym)|uniprotkb:SUGT1A(isoform synonym)|uniprotkb:SUGT1(gene name)|psi-mi:SUGT1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000165416(gene)|ensembl:ENST00000310528(transcript)|intact:EBI-307008(isoform-parent)|uniprotkb:Q9Y2Z0-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:LGEUHwisWjGnJ41eZHpbz7KfxHQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75326 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1753538|uniprotkb:Q1XE81|uniprotkb:Q1XE82|uniprotkb:Q1XE83|uniprotkb:Q1XE84|uniprotkb:Q3MIY5|uniprotkb:B4DDP7|uniprotkb:F5H1S0|ensembl:ENSP00000261918|ensembl:ENSP00000500448 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sem7a_human(display_long)|uniprotkb:SEMA7A(gene name)|psi-mi:SEMA7A(display_short)|uniprotkb:CD108(gene name synonym)|uniprotkb:SEMAL(gene name synonym)|uniprotkb:Semaphorin-L(gene name synonym)|uniprotkb:Semaphorin-K1(gene name synonym)|uniprotkb:John-Milton-Hargen human blood group Ag(gene name synonym)|uniprotkb:JMH blood group antigen(gene name synonym)|uniprotkb:CDw108(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001139501.1|refseq:NP_003603.1|refseq:NP_001139502.1|ensembl:ENSG00000138623(gene)|ensembl:ENSG00000288455(gene)|ensembl:ENST00000261918(transcript)|ensembl:ENST00000671713(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0021988"(olfactory lobe development)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048675"(axon extension)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|interpro:IPR042824|mint:O75326|rcsb pdb:3NVQ|reactome:R-HSA-416700 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:jvLJrmoDZPhZAxms3wWXHescQas9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96EE3-1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10966390|ensembl:ENSP00000382779 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96ee3-1(display_long)|uniprotkb:GATOR complex protein SEH1(gene name synonym)|uniprotkb:SEH1L(gene name)|psi-mi:SEH1L(display_short)|uniprotkb:Nup107-160 subcomplex subunit SEH1(gene name synonym)|uniprotkb:SEC13-like protein(gene name synonym)|uniprotkb:SEC13L(gene name synonym)|uniprotkb:SEH1(gene name synonym)|uniprotkb:SEH1B(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-922818(isoform-parent)|uniprotkb:Q96EE3-1(isoform-parent)|ensembl:ENSG00000085415(gene)|ensembl:ENST00000399892(transcript) - - isoform-comment:Contains a phosphoserine at position 365. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:XNul9RmXOd+D54ZN+nQQZvYVP1o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P55735 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P31431-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16400101 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p31431-2(display_long)|uniprotkb:Amphiglycan(gene name synonym)|uniprotkb:Ryudocan core protein(gene name synonym)|uniprotkb:SDC4(gene name)|psi-mi:SDC4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-3913237(isoform-parent) - - isoform-comment:Soluble form, lacks the transmembrane domain. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/oE7/mq/9r0BfHz1G6ZssNcw26E9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P37837 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1056712|uniprotkb:O00751|uniprotkb:Q8WV32|uniprotkb:B2R8M2|uniprotkb:Q8WZ45|intact:EBI-28976584|ensembl:ENSP00000321259 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:taldo_human(display_long)|uniprotkb:TALDO1(gene name)|psi-mi:TALDO1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:TALDO(gene name synonym)|uniprotkb:TALDOR(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006746.1|ensembl:ENSP00000321259|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000177156(gene)|ensembl:ENST00000319006(transcript)|go:"GO:0004801"(transaldolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001585(Transaldolase)|interpro:IPR004730(Transaldolase AB)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018225|mint:P37837|rcsb pdb:1F05|reactome:R-HSA-163754|reactome:R-HSA-6791055|reactome:R-HSA-6791462|reactome:R-HSA-71336|reactome:R-HSA-8950505 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:+guHJYtBM8f5qHDRdIbNZzs/Sl09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P53992 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15437 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-742673|uniprotkb:Q5W183|uniprotkb:Q9BS15|uniprotkb:Q9BSI2|uniprotkb:Q9H1D7|intact:EBI-1048165|uniprotkb:Q503A9|uniprotkb:D3DW33|ensembl:ENSP00000262544|ensembl:ENSP00000338844|ensembl:ENSP00000366685|ensembl:ENSP00000497473 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sc23b_human(display_long)|uniprotkb:SEC23-related protein B(gene name synonym)|uniprotkb:SEC23B(gene name)|psi-mi:SEC23B(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001166216.1|refseq:NP_006354.2|refseq:NP_116780.1|refseq:NP_116781.1|ensembl:ENSG00000101310(gene)|ensembl:ENST00000262544(transcript)|ensembl:ENST00000336714(transcript)|ensembl:ENST00000377465(transcript)|ensembl:ENST00000650089(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15437|refseq:XP_016883082.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:+3KZ/1jjziSgJRcr81Axquofkl49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8IWZ8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2691671|uniprotkb:Q8WWT4|uniprotkb:Q8TCQ4|uniprotkb:Q8WWT5|uniprotkb:Q6P3X9|uniprotkb:Q9NTG3|uniprotkb:O60378|intact:EBI-28984293|ensembl:ENSP00000247001 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sugp1_human(display_long)|uniprotkb:RNA-binding protein RBP(gene name synonym)|uniprotkb:SUGP1(gene name)|psi-mi:SUGP1(display_short)|uniprotkb:SF4(gene name synonym)|uniprotkb:Splicing factor 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_757386.2|ensembl:ENSP00000247001|ensembl:ENST00000588731|ensembl:ENSP00000465413|ensembl:ENSG00000105705(gene)|ensembl:ENST00000247001(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR035967|interpro:IPR040169|mint:Q8IWZ8|reactome:R-HSA-72163 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:FLQs/3z1CXsBGCBOWAVeh7HzfuI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15436 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-81088|uniprotkb:B2R5P4|uniprotkb:Q8NE16|ensembl:ENSP00000306881|uniprotkb:B3KXI2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sc23a_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)|uniprotkb:SEC23-related protein A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006355.2|ensembl:ENST00000307712(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|ensembl:ENSG00000100934(gene)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15436|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:2YRC|rcsb pdb:2YRD|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|interpro:IPR036180|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:u1FCes02jPb3CGRj1aDkzpbSiuI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P23526 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1053240|uniprotkb:Q96A36|ensembl:ENSP00000217426|uniprotkb:B3KUN3|uniprotkb:F5H737|uniprotkb:A8K307|uniprotkb:E1P5P2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sahh_human(display_long)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:AHCY(gene name)|psi-mi:AHCY(display_short)|uniprotkb:SAHH(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000678.1|refseq:NP_001155238.1|ensembl:ENSG00000101444(gene)|ensembl:ENST00000217426(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002439"(chronic inflammatory response to antigenic stimulus)|go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0019510"(S-adenosylhomocysteine catabolic process)|go:"GO:0030554"(adenyl nucleotide binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042470"(melanosome)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:P23526|rcsb pdb:1A7A|rcsb pdb:1LI4|refseq:XP_011526961.1|refseq:XP_005260374.1|refseq:NP_001309013.1|refseq:NP_001309014.1|rcsb pdb:3NJ4|rcsb pdb:4PFJ|rcsb pdb:4PGF|rcsb pdb:4YVF|rcsb pdb:5W49|rcsb pdb:5W4B|reactome:R-HSA-156581|reactome:R-HSA-1614635|reactome:R-HSA-2408508|reactome:R-HSA-5578997|refseq:XP_016883197.1|refseq:XP_016883198.1|dip:DIP-50557N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:+y7rwgw9EIMaVrkt4/9kbZM44sg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60437 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15424 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-348298|ensembl:ENSP00000292123|uniprotkb:O60406|uniprotkb:B7Z5B6|uniprotkb:F5H0H3|uniprotkb:Q59HH8|uniprotkb:A0AV56|uniprotkb:B7ZLP6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:safb1_human(display_long)|uniprotkb:SAFB(gene name)|psi-mi:SAFB(display_short)|uniprotkb:HAP(gene name synonym)|uniprotkb:HET(gene name synonym)|uniprotkb:SAFB1(gene name synonym)|uniprotkb:HSP27 estrogen response element-TATA box-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030496"(midbody)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000160633(gene)|interpro:IPR034781|interpro:IPR035979|ensembl:ENST00000292123(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|interpro:IPR036361|mint:Q15424|reactome:R-HSA-3899300|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|refseq:NP_002958.2|refseq:NP_001307500.1|refseq:NP_001307501.1|refseq:NP_001188269.1|refseq:NP_001188267.1|refseq:NP_001188268.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Y31we6crSBL4G6uviNAfXyX0xfM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P08621 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1049228|uniprotkb:P78493|uniprotkb:P78494|uniprotkb:Q15364|uniprotkb:Q15686|uniprotkb:Q15687|uniprotkb:Q15689|uniprotkb:Q99377|uniprotkb:Q9UE45|uniprotkb:Q9UE46|uniprotkb:Q9UE47|uniprotkb:Q9UE48|uniprotkb:Q9UFQ6|intact:EBI-3190943|uniprotkb:B3KUA3|ensembl:ENSP00000472998 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ru17_human(display_long)|uniprotkb:SNRNP70(gene name)|psi-mi:SNRNP70(display_short)|uniprotkb:RPU1(gene name synonym)|uniprotkb:U1AP1(gene name synonym)|uniprotkb:RNPU1Z(gene name synonym)|uniprotkb:SNRP70(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003080.2|refseq:NP_001287998.1|ensembl:ENSG00000104852(gene)|ensembl:ENST00000598441(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:1904715"(negative regulation of chaperone-mediated autophagy)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR022023|interpro:IPR034143|interpro:IPR035979|mint:P08621|rcsb pdb:2L5I|rcsb pdb:2L5J|rcsb pdb:3CW1|rcsb pdb:3PGW|rcsb pdb:4PJO|rcsb pdb:4PKD|rcsb pdb:6QX9|rcsb pdb:7B0Y|reactome:R-HSA-72163|dip:DIP-29406N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/P72B69q5f0TX4vTr4GuRrtgiRM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13277-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10968862 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q13277-2(display_long)|uniprotkb:STX3(gene name)|psi-mi:STX3(display_short)|uniprotkb:STX3A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1394295(isoform-parent)|uniprotkb:Q13277-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:NwbBp/1Mt7wnO+9m1Ot7CmT2CRA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P08865 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96DX4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2341274|uniprotkb:Q8ND53|uniprotkb:Q6UX21|ensembl:ENSP00000377942|ensembl:ENSP00000443176 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rspry_human(display_long)|uniprotkb:RSPRY1(gene name)|psi-mi:RSPRY1(display_short)|uniprotkb:KIAA1972(gene name synonym)|uniprotkb:UNQ328/PRO444(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001292092.1|refseq:NP_001292093.1|refseq:NP_001292111.1|refseq:NP_588609.1|refseq:XP_005256277.1|ensembl:ENSG00000159579(gene)|ensembl:ENST00000394420(transcript)|ensembl:ENST00000537866(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0046872"(metal ion binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035774|interpro:IPR043136 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:WIh5Nn9L+KH2Zw9m3M+sFpMo2/M9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9P2E9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2371806|uniprotkb:A2A2S6|uniprotkb:A6NCN6|uniprotkb:O75300|uniprotkb:O75301|uniprotkb:Q5W165|uniprotkb:Q96SB2|uniprotkb:Q9BWP1|uniprotkb:Q9H476|uniprotkb:A0A0A0MRV0|intact:EBI-28985482|ensembl:ENSP00000246043|ensembl:ENSP00000367044 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rrbp1_human(display_long)|uniprotkb:RRBP1(gene name)|psi-mi:RRBP1(display_short)|uniprotkb:KIAA1398(gene name synonym)|uniprotkb:Ribosome receptor protein(gene name synonym)|uniprotkb:180 kDa ribosome receptor homolog(gene name synonym)|uniprotkb:ES/130-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001036041.1|refseq:NP_004578.2|ensembl:ENSP00000246043|ensembl:ENST00000360807|ensembl:ENSP00000354045|ensembl:ENST00000377807|ensembl:ENSP00000367038|ensembl:ENSP00000367044|ensembl:ENSG00000125844(gene)|ensembl:ENST00000246043(transcript)|ensembl:ENST00000377813(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR040248|mint:Q9P2E9 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:uOiVzIAM5bsSl2s1BSIfnUtZ3Ms9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NQG5 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y3F4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-727414|uniprotkb:Q9UQC8|uniprotkb:Q9NTK0|uniprotkb:Q5TZT4|intact:EBI-6190807|uniprotkb:B4DNJ6|uniprotkb:B2R5S5|ensembl:ENSP00000392270 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:strap_human(display_long)|uniprotkb:UNR-interacting protein(gene name synonym)|uniprotkb:WD-40 repeat protein PT-WD(gene name synonym)|uniprotkb:MAP activator with WD repeats(gene name synonym)|uniprotkb:STRAP(gene name)|psi-mi:STRAP(display_short)|uniprotkb:MAWD(gene name synonym)|uniprotkb:UNRIP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_009109.3|ensembl:ENSG00000023734(gene)|ensembl:ENST00000419869(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:Q9Y3F4|reactome:R-HSA-2173788 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/IqZt6BHPxD3S/THUZry4+QUvCE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P04843 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q07666 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|ensembl:ENSG00000121774(gene)|ensembl:ENST00000327300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|reactome:R-HSA-8849468 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y597-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399614 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9y597-2(display_long)|uniprotkb:KCTD3(gene name)|psi-mi:KCTD3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 uniprotkb:Q9Y597(isoform-parent)|uniprotkb:Q9Y597-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:qWxIPdlTweejLct/ThEliOfvc549606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P12277 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y6M4-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399650|ensembl:ENSP00000353904 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9y6m4-2(display_long)|uniprotkb:CSNK1G3(gene name)|psi-mi:CSNK1G3(display_short)|uniprotkb:3L(isoform synonym)|uniprotkb:CSNK1G3L(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1383789(isoform-parent)|uniprotkb:Q9Y6M4-2(isoform-parent)|ensembl:ENSG00000151292(gene)|ensembl:ENST00000360683(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:tju3wZFY03ZN9ZKpzBlPDDwTHgQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P48730-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-9087876|ensembl:ENSP00000376146 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p48730-2(display_long)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-751621(isoform-parent)|ensembl:ENSG00000141551(gene)|ensembl:ENST00000392334(transcript)|uniprotkb:P48730-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:DKYeQTtdg+u5Gm9wscDkiTs7Blg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P48729 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1383726|uniprotkb:Q96HD2|uniprotkb:Q5U046|uniprotkb:Q5U047|uniprotkb:Q6FGA2|uniprotkb:Q4JJA0|uniprotkb:Q9UDK3|intact:EBI-11048253|uniprotkb:D3DQG0|uniprotkb:D3DQG1|uniprotkb:Q71TU5|ensembl:ENSP00000367074 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:kc1a_human(display_long)|uniprotkb:CSNK1A1(gene name)|psi-mi:CSNK1A1(display_short)|uniprotkb:CK1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001020276.1|refseq:NP_001883.4|refseq:NP_001258670.1|refseq:NP_001258671.1|dip:DIP-40367N|ensembl:ENSG00000113712(gene)|ensembl:ENST00000377843(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051301"(cell division)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904424"(regulation of GTP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48729|rcsb pdb:5FQD|rcsb pdb:6GZD|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5635838 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:2rG1/sMVnsRKUEWsLhLAyHvqPnY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8N163-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399643 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q8n163-2(display_long)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:NET35(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:DBC1(gene name synonym)|uniprotkb:KIAA1967(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-355410(isoform-parent)|uniprotkb:Q8N163-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Y/i1bvtaGZoPAW2JrV6b5rmv1gM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y287 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2866431|uniprotkb:Q5W0A3|uniprotkb:Q96B24|uniprotkb:Q9NYH1|ensembl:ENSP00000497221 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:itm2b_human(display_long)|uniprotkb:ITM2B(gene name)|psi-mi:ITM2B(display_short)|uniprotkb:BRI(gene name synonym)|uniprotkb:BRI2(gene name synonym)|uniprotkb:Protein E25B(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)|uniprotkb:Immature BRI2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_068839.1|ensembl:ENSG00000136156(gene)|ensembl:ENST00000647800(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|reactome:R-HSA-977225 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:9mHhC4Z61CsmOsTh/1K9oj2NezA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P46940 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15181 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-712298|ensembl:ENSP00000362329|uniprotkb:Q2M348|uniprotkb:Q5SQT7|uniprotkb:Q6P7P4|uniprotkb:Q9UQJ5|uniprotkb:Q9Y5B1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ipyr_human(display_long)|uniprotkb:Pyrophosphate phospho-hydrolase(gene name synonym)|uniprotkb:PPA1(gene name)|psi-mi:PPA1(display_short)|uniprotkb:IOPPP(gene name synonym)|uniprotkb:PP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000180817(gene)|ensembl:ENST00000373232(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q15181|rcsb pdb:6C45|rcsb pdb:7BTN|rcsb pdb:7CMO|reactome:R-HSA-379716|reactome:R-HSA-71737|refseq:NP_066952.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:1094gn9aeisgfDUhIroRn2iqom49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14974 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00505 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P52294 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q12905 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P30740 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2831526|uniprotkb:Q53FB9|uniprotkb:A8K5L2|uniprotkb:Q5W0E1|uniprotkb:Q9UDF8|uniprotkb:B4DNT0|ensembl:ENSP00000370115 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ileu_human(display_long)|uniprotkb:SERPINB1(gene name)|psi-mi:SERPINB1(display_short)|uniprotkb:ELANH2(gene name synonym)|uniprotkb:MNEI(gene name synonym)|uniprotkb:PI2(gene name synonym)|uniprotkb:Monocyte/neutrophil elastase inhibitor(gene name synonym)|uniprotkb:Peptidase inhibitor 2(gene name synonym)|uniprotkb:Serpin B1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:XP_011512635.1|refseq:XP_011512636.1|ensembl:ENSG00000021355(gene)|ensembl:ENST00000380739(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015557(Protease inhibitor I4, serpin B1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:4GA7|reactome:R-HSA-6798695|refseq:NP_109591.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:5IolAmA+BrS4XHZZEQgf05kA4pE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P23588 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P38919 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-299104|ensembl:ENSP00000497641|ensembl:ENSP00000497661|uniprotkb:Q15033|uniprotkb:Q96A18|uniprotkb:Q6IBQ2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:if4a3_human(display_long)|uniprotkb:KIAA0111(gene name synonym)|uniprotkb:EIF4A3(gene name)|psi-mi:EIF4A3(display_short)|uniprotkb:DDX48(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A isoform 3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-3(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DDX48(gene name synonym)|uniprotkb:DEAD box protein 48(gene name synonym)|uniprotkb:Eukaryotic initiation factor 4A-like NUK-34(gene name synonym)|uniprotkb:Nuclear matrix protein 265(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008306"(associative learning)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072715"(cellular response to selenite ion)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904570"(negative regulation of selenocysteine incorporation)|go:"GO:1904574"(negative regulation of selenocysteine insertion sequence binding)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P38919|rcsb pdb:2HXY|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2J0U|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:4C9B|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6YVH|rcsb pdb:7A5P|reactome:R-HSA-1169408|reactome:R-HSA-159236|reactome:R-HSA-429947|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|ensembl:ENST00000647795(transcript)|ensembl:ENST00000649764(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|ensembl:ENSG00000141543(gene)|refseq:NP_055555.1|dip:DIP-33218N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:8e6e4HlM1GsYqqgXyJ9XgzxLzls9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P60842 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00425 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y6M1-1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-5455628|ensembl:ENSP00000320204 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9y6m1-1(display_long)|uniprotkb:IGF2BP2(gene name)|psi-mi:IGF2BP2(display_short)|uniprotkb:IMP2(gene name synonym)|uniprotkb:VICKZ2(gene name synonym)|uniprotkb:Hepatocellular carcinoma autoantigen p62(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 2(gene name synonym)|uniprotkb:VICKZ family member 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1024419(isoform-parent)|ensembl:ENSG00000073792(gene)|ensembl:ENST00000346192(transcript)|uniprotkb:Q9Y6M1-1(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:aBPRtk8xsIFaT138rQ9KS64E1bY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NZI8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P05198 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1056162|ensembl:ENSP00000256383|ensembl:ENSP00000425299 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:if2a_human(display_long)|uniprotkb:EIF2S1(gene name)|psi-mi:EIF2S1(display_short)|uniprotkb:EIF2A(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004085.1|ensembl:ENSG00000134001(gene)|ensembl:ENST00000256383(transcript)|ensembl:ENST00000466499(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|mint:P05198|rcsb pdb:1KL9|rcsb pdb:1Q8K|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|dip:DIP-39418N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:hG3fLbQuFpe5z8zS/bt/TnpEpzA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75874 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-715695|uniprotkb:Q567U4|uniprotkb:Q6FHQ6|uniprotkb:Q7Z3V0|uniprotkb:Q93090|uniprotkb:Q9NTJ9|uniprotkb:Q9UKW8|ensembl:ENSP00000260985|ensembl:ENSP00000390265|ensembl:ENSP00000410513 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:idhc_human(display_long)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:PICD(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005887.2|refseq:NP_001269315.1|refseq:NP_001269316.1|ensembl:ENSG00000138413(gene)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:1T09|rcsb pdb:1T0L|rcsb pdb:3INM|rcsb pdb:3MAP|rcsb pdb:3MAR|rcsb pdb:3MAS|rcsb pdb:4I3K|go:"GO:0060696"(regulation of phospholipid catabolic process)|rcsb pdb:4I3L|rcsb pdb:4KZO|rcsb pdb:4L03|rcsb pdb:4L04|rcsb pdb:4L06|rcsb pdb:4UMX|rcsb pdb:4UMY|rcsb pdb:4XRX|rcsb pdb:4XS3|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008585"(female gonad development)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000345146(transcript)|go:"GO:0045296"(cadherin binding)|ensembl:ENST00000415913(transcript)|ensembl:ENST00000446179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|rcsb pdb:5DE1|rcsb pdb:5GIR|rcsb pdb:5K10|rcsb pdb:5K11|rcsb pdb:5L57|rcsb pdb:5L58|rcsb pdb:5LGE|rcsb pdb:5SUN|rcsb pdb:5SVF|rcsb pdb:5TQH|rcsb pdb:5YFM|rcsb pdb:5YFN|rcsb pdb:6ADG|rcsb pdb:6B0Z|rcsb pdb:6BKX|rcsb pdb:6BKY|rcsb pdb:6BKZ|rcsb pdb:6BL0|rcsb pdb:6BL1|rcsb pdb:6BL2|rcsb pdb:6IO0|rcsb pdb:6VEI|rcsb pdb:6VG0|reactome:R-HSA-389542|reactome:R-HSA-6798695|reactome:R-HSA-2978092|rcsb pdb:6O2Y|rcsb pdb:6O2Z|rcsb pdb:6PAY|rcsb pdb:6Q6F|rcsb pdb:6U4J|reactome:R-HSA-9033241|dip:DIP-59311N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RFBziMEb70PKCzUCJm2jd40y44M9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P54105 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-724693|uniprotkb:Q0VDK6|uniprotkb:Q9NRD2|uniprotkb:Q9NRD3|uniprotkb:B2RCS9|ensembl:ENSP00000433919|ensembl:ENSP00000434311 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:icln_human(display_long)|uniprotkb:Chloride conductance regulatory protein ICln(gene name synonym)|uniprotkb:Chloride channel, nucleotide sensitive 1A(gene name synonym)|uniprotkb:Chloride ion current inducer protein(gene name synonym)|uniprotkb:Reticulocyte pICln(gene name synonym)|uniprotkb:CLNS1A(gene name)|psi-mi:CLNS1A(display_short)|uniprotkb:ICLN(gene name synonym)|uniprotkb:CLCI(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001284.1|refseq:NP_001298128.1|refseq:NP_001298129.1|refseq:NP_001298130.1|refseq:NP_001298131.1|ensembl:ENSG00000074201(gene)|ensembl:ENST00000525428(transcript)|ensembl:ENST00000528364(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|interpro:IPR003521(Nucleotide-sensitive chloride conductance regulator)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039924|mint:P54105|rcsb pdb:6V0O|reactome:R-HSA-191859|dip:DIP-44185N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:dGx9UwPj9VBp1CiPTRCXnT3IYt89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P11142 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P08107 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6YN16 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1056665|uniprotkb:A8K1L4|uniprotkb:A8K8X1|uniprotkb:A8MSV3|uniprotkb:Q658M8|uniprotkb:Q9BT58|ensembl:ENSP00000381785 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hsdl2_human(display_long)|uniprotkb:HSDL2(gene name)|psi-mi:HSDL2(display_short)|uniprotkb:C9orf99(gene name synonym)|uniprotkb:SDR13C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 13C member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001182751.1|refseq:NP_115679.2|ensembl:ENSG00000119471(gene)|ensembl:ENST00000398805(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR036291|interpro:IPR036527|rcsb pdb:3KVO - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:9p5t2957ZP6MwNTNgdfX0rUepnI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P08238 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P07900-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-6190772|ensembl:ENSP00000335153 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p07900-2(display_long)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)|uniprotkb:HSP90AA1-2(isoform synonym)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000080824(gene)|ensembl:ENST00000334701(transcript)|intact:EBI-296047(isoform-parent)|uniprotkb:P07900-2(isoform-parent) - - isoform-comment:"Variant in position: 71:M->L (in dbSNP:rs8005905)." figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zSFsoTnWMCxMgg5CMgkY21uBpb89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92598-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399635|ensembl:ENSP00000369768 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q92598-2(display_long)|uniprotkb:Antigen NY-CO-25(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-356829(isoform-parent)|ensembl:ENSG00000120694(gene)|ensembl:ENST00000380405(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HR/g+Gi95m19/VHfkmkeEndlybs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NZL4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356763|uniprotkb:O95351|uniprotkb:Q6ZNU5|uniprotkb:B3KQP0|uniprotkb:B4DG11|ensembl:ENSP00000255631|ensembl:ENSP00000398244|ensembl:ENSP00000467574 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hpbp1_human(display_long)|uniprotkb:HSPBP1(gene name)|psi-mi:HSPBP1(display_short)|uniprotkb:HSPBP(gene name synonym)|uniprotkb:PP1845(orf name)|uniprotkb:Heat shock protein-binding protein 1(gene name synonym)|uniprotkb:Hsp70-interacting protein 1(gene name synonym)|uniprotkb:Hsp70-binding protein 2(gene name synonym)|uniprotkb:Hsp70-interacting protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001123578.1|refseq:NP_036399.3|ensembl:ENSG00000133265(gene)|ensembl:ENST00000255631(transcript)|ensembl:ENST00000433386(transcript)|ensembl:ENST00000587922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013918(Nucleotide exchange factor Fes1)|interpro:IPR016024(Armadillo-type fold)|mint:Q9NZL4|rcsb pdb:1XQR|rcsb pdb:1XQS|refseq:NP_001284529.1|refseq:XP_016882033.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:26Au2GesO5ysT/yhYX/0oOO9Md89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60506-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-5455760|ensembl:ENSP00000347380|ensembl:ENSP00000397782|ensembl:ENSP00000502974|ensembl:ENSP00000503246 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o60506-3(display_long)|uniprotkb:hnRNP Q1(isoform synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1024357(isoform-parent)|ensembl:ENSG00000135316(gene)|ensembl:ENST00000355238(transcript)|ensembl:ENST00000444272(transcript)|ensembl:ENST00000676637(transcript)|ensembl:ENST00000678528(transcript) - - isoform-comment:"May be due to a competing donor splice site and to an exon inclusion. Ref.5 (AAK59705) sequence is in conflict in positions: 550:QG->V." figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:jpkoqoWt+e91dIkyxegkIBBLe3g9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P52272-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11033003|ensembl:ENSP00000325732 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p52272-2(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym)|uniprotkb:M1-M2(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-486809(isoform-parent)|ensembl:ENSG00000099783(gene)|ensembl:ENST00000348943(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:UO31ACSY94PNTXcG+GhHR4dktf89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P14866 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P52597 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14103-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-432539|ensembl:ENSP00000313327|intact:EBI-8518712|intact:MINT-4853530 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q14103-3(display_long)|uniprotkb:p40(isoform synonym)|uniprotkb:Dx7(isoform synonym)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000138668(gene)|ensembl:ENST00000353341(transcript)|intact:EBI-299674(hnrpd_human) - - isoform-comment:Contains a omega-N-methylarginine at position 282. Contains a N6-acetyllysine at position 292. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:CcPoMLTFV+XA/t8uFs5BNpgNb6k9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P07910-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-5280084|ensembl:ENSP00000442816|ensembl:ENSP00000450544|ensembl:ENSP00000450725|ensembl:ENSP00000451176 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p07910-2(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 uniprotkb:P07910-2(isoform-parent)|intact:EBI-357966(isoform-parent)|ensembl:ENSG00000092199(gene)|ensembl:ENST00000430246(transcript)|ensembl:ENST00000553300(transcript)|ensembl:ENST00000554969(transcript)|ensembl:ENST00000556897(transcript) - - isoform-comment:Contains a phosphoserine at position 107. Contains a phosphoserine at position 108. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:r7AhGozE3aHdynLr8DrXPRtOuyI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P31942-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399628|ensembl:ENSP00000346726 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p31942-2(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym)|uniprotkb:2H9A(isoform synonym)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000096746(gene)|ensembl:ENST00000354695(transcript)|intact:EBI-711437(isoform-parent)|uniprotkb:P31942-2(isoform-parent) - - isoform-comment:Contains a omega-N-methylarginine at position 116. Contains a omega-N-methylarginine at position 121. Contains a omega-N-methylarginine at position 129. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:EcEiHtvtiNckv4jPK/MbPEOwtm09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14979-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399620|ensembl:ENSP00000338552|ensembl:ENSP00000473677|ensembl:ENSP00000480156|ensembl:ENSP00000485954|ensembl:ENSP00000486452 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o14979-2(display_long)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:JKTBP1(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000152795(gene)|ensembl:ENST00000349655(transcript)|ensembl:ENST00000507721(transcript)|ensembl:ENST00000602300(transcript)|ensembl:ENST00000630114(transcript)|ensembl:ENST00000630827(transcript)|uniprotkb:O14979-2(isoform-parent)|intact:EBI-299727(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:dc7ExHSzQ/VanNn2FJnqcjTKkRE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00291 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-473886|uniprotkb:O00328|uniprotkb:Q8TDL4|uniprotkb:Q2TB58|uniprotkb:V5LU97|uniprotkb:B4E3I7|uniprotkb:E7ES17|ensembl:ENSP00000336747 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hip1_human(display_long)|uniprotkb:HIP1(gene name)|psi-mi:HIP1(display_short)|uniprotkb:Huntingtin-interacting protein I(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0051015"(actin filament binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099637"(neurotransmitter receptor transport)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR030554|interpro:IPR032422|interpro:IPR035964|mint:O00291|rcsb pdb:2NO2|rcsb pdb:2QA7|rcsb pdb:3I00|reactome:R-HSA-8856828|refseq:NP_005329.3|refseq:NP_001230127.1|refseq:XP_005250361.1|refseq:XP_011514418.1|ensembl:ENSG00000127946(gene)|ensembl:ENST00000336926(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050821"(protein stabilization)|dip:DIP-17041N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:tv7gJyUeUPo98+42G8L980EnE/c9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P42694 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1210654|uniprotkb:I6L9H4|ensembl:ENSP00000351524 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:helz_human(display_long)|uniprotkb:HELZ(gene name)|psi-mi:HELZ(display_short)|uniprotkb:KIAA0054(gene name synonym)|uniprotkb:DRHC(gene name synonym)|uniprotkb:Down-regulated in human cancers protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_055692.2|ensembl:ENSG00000198265(gene)|ensembl:ENST00000358691(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|dip:DIP-39352N|interpro:IPR027417|interpro:IPR036855|interpro:IPR041677|interpro:IPR041679 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:q+2P+W7RDRl2CyPhdEsvONGaM0U9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P51610 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P16401 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-5327611|uniprotkb:Q14529|uniprotkb:Q3MJ42|ensembl:ENSP00000330074 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:h15_human(display_long)|uniprotkb:H1-5(gene name)|psi-mi:H1-5(display_short)|uniprotkb:H1F5(gene name synonym)|uniprotkb:HIST1H1B(gene name synonym)|uniprotkb:Histone H1a(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005313.1|ensembl:ENSG00000184357(gene)|ensembl:ENST00000331442(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0050821"(protein stabilization)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|rcsb pdb:2FE2|rcsb pdb:2RHI|reactome:R-HSA-140342|reactome:R-HSA-2559584|go:"GO:0000792"(heterochromatin) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:b81Z7VA09Na0XXDfR0HtaZmq1g89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P16403 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UBP9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3922283|uniprotkb:Q9BVL3|uniprotkb:B2RB51|uniprotkb:Q53RF3|uniprotkb:Q53PC1|uniprotkb:D3DPH1|uniprotkb:B8ZZ72|uniprotkb:B4DQ40|uniprotkb:E9PB86|ensembl:ENSP00000352047|ensembl:ENSP00000386289|ensembl:ENSP00000386732|ensembl:ENSP00000386867 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gulp1_human(display_long)|uniprotkb:GULP1(gene name)|psi-mi:GULP1(display_short)|uniprotkb:CED6(gene name synonym)|uniprotkb:GULP(gene name synonym)|uniprotkb:Cell death protein 6 homolog(gene name synonym)|uniprotkb:PTB domain adapter protein CED-6(gene name synonym)|uniprotkb:Protein GULP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_057399.1|refseq:NP_001239598.1|refseq:NP_001239597.1|refseq:XP_016859795.1|ensembl:ENSG00000144366(gene)|ensembl:ENST00000359135(transcript)|ensembl:ENST00000409580(transcript)|ensembl:ENST00000409609(transcript)|ensembl:ENST00000409830(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006869"(lipid transport)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:6ITU - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:d8WIyZvwLJGs0CGArWArKium7Zw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P11169 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-725116|uniprotkb:Q6I9U2|uniprotkb:Q9UG15|uniprotkb:D3DUU6|uniprotkb:B2R606|ensembl:ENSP00000075120 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gtr3_human(display_long)|uniprotkb:Glucose transporter type 3, brain(gene name synonym)|uniprotkb:SLC2A3(gene name)|psi-mi:SLC2A3(display_short)|uniprotkb:GLUT3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_008862.1|ensembl:ENSG00000059804(gene)|ensembl:ENST00000075120(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005536"(glucose binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043204"(perikaryon)|interpro:IPR020846|interpro:IPR036259|mint:P11169|rcsb pdb:4ZW9|rcsb pdb:4ZWB|rcsb pdb:4ZWC|rcsb pdb:5C65|rcsb pdb:7CRZ|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-6798695|reactome:R-HSA-9022699|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002945(Glucose transporter GLUT3, type 3)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:4lvD/2COzfHcIKxN1l9FsXOJWnk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P11166 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-717153|uniprotkb:A8K9S6|uniprotkb:O75535|uniprotkb:Q147X2|uniprotkb:B2R620|uniprotkb:D3DPX0|uniprotkb:Q0P512|ensembl:ENSP00000416293 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gtr1_human(display_long)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)|uniprotkb:HepG2 glucose transporter(gene name synonym)|uniprotkb:SLC2A1(gene name)|psi-mi:SLC2A1(display_short)|uniprotkb:GLUT1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006507.2|ensembl:ENSG00000117394(gene)|ensembl:ENST00000426263(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0072562"(blood microparticle)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11166|rcsb pdb:1SUK|rcsb pdb:4PYP|rcsb pdb:5EQG|rcsb pdb:5EQH|rcsb pdb:5EQI|rcsb pdb:6THA|reactome:R-HSA-189200|reactome:R-HSA-196836|reactome:R-HSA-422356|reactome:R-HSA-5619043|reactome:R-HSA-5653890|dip:DIP-23N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:72DLUG1CFkqcf92goIZBZ4+zuls9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P78347-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-12033200|ensembl:ENSP00000477837 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p78347-2(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000263001(gene)|ensembl:ENST00000620879(transcript)|intact:EBI-359622(isoform-parent)|uniprotkb:P78347-2(isoform-parent) - - isoform-comment:Contains a phosphoserine at position 278. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:oAtUCyUBi1ZfU3hGg2tNzlEhxgg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92896-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399500 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q92896-2(display_long)|uniprotkb:GLG1(gene name)|psi-mi:GLG1(display_short)|uniprotkb:CFR1(gene name synonym)|uniprotkb:ESL1(gene name synonym)|uniprotkb:MG160(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 uniprotkb:Q92896(isoform-parent)|uniprotkb:Q92896-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:a8z4t1+GXPcVKty+vILOfjh5fTU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P11021 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P38646 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NQ84-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399541|ensembl:ENSP00000498839 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9nq84-2(display_long)|uniprotkb:Retinoic acid-induced gene 3 protein(gene name synonym)|uniprotkb:PSEC0087(orf name)|uniprotkb:GPRC5C(gene name)|psi-mi:GPRC5C(display_short)|uniprotkb:RAIG3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000170412(gene)|ensembl:ENST00000652294(transcript)|intact:EBI-348052(isoform-parent)|uniprotkb:Q9NQ84-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HDdn9Sfa1nxpbKiqyrucPF5ziu89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P51654 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-5654198|uniprotkb:C9JLE3|uniprotkb:Q2L880|uniprotkb:G3V1R0|uniprotkb:Q2L882|ensembl:ENSP00000359854 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gpc3_human(display_long)|uniprotkb:GTR2-2(gene name synonym)|uniprotkb:Intestinal protein OCI-5(gene name synonym)|uniprotkb:MXR7(gene name synonym)|uniprotkb:OCI5(gene name synonym)|uniprotkb:GPC3(gene name)|psi-mi:GPC3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001158091.1|dip:DIP-61509N|refseq:NP_004475.1|refseq:NP_001158089.1|ensembl:ENSG00000147257(gene)|ensembl:ENST00000370818(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009617"(response to bacterium)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0010171"(body morphogenesis)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0016477"(cell migration)|go:"GO:0030282"(bone mineralization)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060422"(peptidyl-dipeptidase inhibitor activity)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072111"(cell proliferation involved in kidney development)|go:"GO:0072138"(mesenchymal cell proliferation involved in ureteric bud development)|go:"GO:0072180"(mesonephric duct morphogenesis)|go:"GO:0072203"(cell proliferation involved in metanephros development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1905475"(regulation of protein localization to membrane)|go:"GO:2000050"(regulation of non-canonical Wnt signaling pathway)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR001863(Glypican)|interpro:IPR015501(Glypican 3)|interpro:IPR019803|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-381426|reactome:R-HSA-4420332|reactome:R-HSA-8957275|reactome:R-HSA-975634 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:+H2PtA0Y61S+2l56UPxwxBpCosc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P46926 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-749356|uniprotkb:D3DQE7|uniprotkb:B7Z3X4|ensembl:ENSP00000311876|ensembl:ENSP00000423485|ensembl:ENSP00000423674|ensembl:ENSP00000424275 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gnpi1_human(display_long)|uniprotkb:Glucosamine-6-phosphate deaminase 1(gene name synonym)|uniprotkb:Oscillin(gene name synonym)|uniprotkb:GNPDA1(gene name)|psi-mi:GNPDA1(display_short)|uniprotkb:GNPI(gene name synonym)|uniprotkb:HLN(gene name synonym)|uniprotkb:KIAA0060(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005462.1|refseq:XP_011535839.1|refseq:XP_006714810.1|ensembl:ENST00000311337(transcript)|ensembl:ENST00000500692(transcript)|ensembl:ENST00000503794(transcript)|ensembl:ENST00000508177(transcript)|go:"GO:0004342"(glucosamine-6-phosphate deaminase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006043"(glucosamine catabolic process)|go:"GO:0006046"(N-acetylglucosamine catabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0007338"(single fertilization)|go:"GO:0019262"(N-acetylneuraminate catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004547(Glucosamine-6-phosphate isomerase)|interpro:IPR006148(Glucosamine/galactosamine-6-phosphate isomerase)|interpro:IPR018321|interpro:IPR037171|rcsb pdb:1NE7|reactome:R-HSA-70171|ensembl:ENSG00000113552(gene) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:5TTqdwo8fdjSLGVvC4brLfghfRU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P63092 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1047114|uniprotkb:P04895|uniprotkb:Q12927|uniprotkb:Q5JWD2|uniprotkb:Q5JWD4|uniprotkb:Q5JWD5|uniprotkb:Q6NR75|uniprotkb:Q6NXS0|uniprotkb:Q8TBC0|uniprotkb:Q96H70|uniprotkb:Q14433|uniprotkb:Q32P26|uniprotkb:E1P5G5|ensembl:ENSP00000360126|uniprotkb:A6NI00|intact:EBI-10977858 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gnas2_human(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:GSP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001070958.1|refseq:NP_001296769.1|refseq:NP_536350.2|refseq:NP_000507.1|refseq:NP_001070956.1|refseq:NP_001070957.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371085(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63092|rcsb pdb:5G53|rcsb pdb:5UZ7|rcsb pdb:5VAI|rcsb pdb:6AU6|rcsb pdb:6B3J|rcsb pdb:6E3Y|rcsb pdb:6E67|rcsb pdb:6EG8|rcsb pdb:6GDG|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LPB|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6ORV|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VN7|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XOX|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7BPH|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D7M|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7KH0|rcsb pdb:7LCI|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821|refseq:NP_536351.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:fUnrdxwx4bBAqE3iO2cCB3UInyg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P50148 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3909604|uniprotkb:Q6NT27|uniprotkb:Q92471|uniprotkb:O15108|uniprotkb:Q9BZB9|uniprotkb:Q13462|ensembl:ENSP00000286548 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gnaq_human(display_long)|uniprotkb:GNAQ(gene name)|psi-mi:GNAQ(display_short)|uniprotkb:GAQ(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002063.2|ensembl:ENSG00000156052(gene)|ensembl:ENST00000286548(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P50148|rcsb pdb:6VU5|reactome:R-HSA-112043|reactome:R-HSA-202040|reactome:R-HSA-399997|reactome:R-HSA-416476|reactome:R-HSA-418592|reactome:R-HSA-428930|reactome:R-HSA-434316|reactome:R-HSA-456926|reactome:R-HSA-6814122|dip:DIP-41652N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ExDRSmmaTXllLWSDrc79rkxxAqQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P08754 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357563|uniprotkb:Q5TZX1|uniprotkb:P17539|ensembl:ENSP00000358867 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gnai3_human(display_long)|uniprotkb:GNAI3(gene name)|psi-mi:GNAI3(display_short)|uniprotkb:"G(i) alpha-3"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006487.1|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|ensembl:ENSG00000065135(gene)|ensembl:ENST00000369851(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007049"(cell cycle)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0042588"(zymogen granule)|go:"GO:0045121"(membrane raft)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:2IHB|rcsb pdb:2ODE|rcsb pdb:2V4Z|rcsb pdb:4G5O|rcsb pdb:4G5R|rcsb pdb:4G5S|rcsb pdb:7E9H|rcsb pdb:7KH0|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-9009391|reactome:R-HSA-9660821 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:npLeIXVzrV8y0trCCII5rivIRYQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P04899 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14344 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-465387|ensembl:ENSP00000400717|uniprotkb:Q8TD70|uniprotkb:B7Z7R0|uniprotkb:F5H1G8|uniprotkb:B2R977 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gna13_human(display_long)|uniprotkb:GNA13(gene name)|psi-mi:GNA13(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000120063(gene)|ensembl:ENST00000439174(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-428930|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-456926|refseq:NP_006563.2|refseq:NP_001269354.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ZYmlpIogjya3/ejteQS1YC+LqKI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P29992 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1171154|uniprotkb:O15109|uniprotkb:Q14350|uniprotkb:Q6IB00|ensembl:ENSP00000078429 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gna11_human(display_long)|uniprotkb:GNA11(gene name)|psi-mi:GNA11(display_short)|uniprotkb:GA11(gene name synonym)|uniprotkb:"Guanine nucleotide-binding protein G(y) subunit alpha"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002058.2|ensembl:ENSG00000088256(gene)|ensembl:ENST00000078429(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0045202"(synapse)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071467"(cellular response to pH)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P29992|rcsb pdb:6OIJ|reactome:R-HSA-112043|reactome:R-HSA-202040|reactome:R-HSA-399997|reactome:R-HSA-416476|reactome:R-HSA-418592|reactome:R-HSA-428930|reactome:R-HSA-434316|reactome:R-HSA-456926|reactome:R-HSA-6814122 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:tb/5F5leSFWxmZySr0PzfPIbLAQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O76003 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14908 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92820 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3045534|ensembl:ENSP00000260118 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000137563(gene)|ensembl:ENST00000260118(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0034722"(gamma-glutamyl-peptidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0046900"(tetrahydrofolylpolyglutamate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070500"(poly-gamma-glutamate metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|rcsb pdb:1L9X|reactome:R-HSA-6798695|refseq:NP_003869.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NWZ8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2626001|uniprotkb:C4AMC4|uniprotkb:Q2LJ66|uniprotkb:Q6ZV27|ensembl:ENSP00000369895|ensembl:ENSP00000381398|ensembl:ENSP00000505279|ensembl:ENSP00000505429 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gemi8_human(display_long)|uniprotkb:GEMIN8(gene name)|psi-mi:GEMIN8(display_short)|uniprotkb:FAM51A1(gene name synonym)|uniprotkb:Protein FAM51A1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001035944.1|refseq:NP_001035945.1|refseq:NP_060326.1|refseq:XP_016885106.1|refseq:XP_016885107.1|ensembl:ENSG00000046647(gene)|ensembl:ENST00000380523(transcript)|ensembl:ENST00000398355(transcript)|ensembl:ENST00000477386(transcript)|ensembl:ENST00000680255(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR034754|mint:Q9NWZ8|rcsb pdb:7BBL|reactome:R-HSA-191859 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Lvyive5mtL+89HujsYibFUTFP1k9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8TEQ6 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-443630|ensembl:ENSP00000285873|uniprotkb:Q14CV0|uniprotkb:Q8WWV4|uniprotkb:Q969W4|uniprotkb:Q9H9K3|uniprotkb:Q9UFI5 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gemi5_human(display_long)|uniprotkb:GEMIN5(gene name)|psi-mi:GEMIN5(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000082516(gene)|ensembl:ENST00000285873(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0032797"(SMN complex)|go:"GO:0034718"(SMN-Gemin2 complex)|interpro:IPR036322|mint:Q8TEQ6|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5GXH|rcsb pdb:5GXI|rcsb pdb:5H1J|rcsb pdb:5H1K|go:"GO:0043022"(ribosome binding)|rcsb pdb:5H1L|rcsb pdb:5H1M|rcsb pdb:5H3S|rcsb pdb:5H3T|rcsb pdb:5H3U|rcsb pdb:5TEE|rcsb pdb:5TEF|rcsb pdb:5THA|rcsb pdb:6RNQ|rcsb pdb:6RNS|reactome:R-HSA-191859|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|refseq:NP_056280.2|refseq:NP_001239085.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:9D6k6KGv+klNdYzgQClnthCYJuo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P57678 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14893 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-443648|ensembl:ENSP00000250379|ensembl:ENSP00000308533|ensembl:ENSP00000379548|ensembl:ENSP00000416827|uniprotkb:Q2M3B3|uniprotkb:Q9H4F5|uniprotkb:Q9NS77|uniprotkb:Q9NS78|uniprotkb:Q9NS79|uniprotkb:B2R9W8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gemi2_human(display_long)|uniprotkb:GEMIN2(gene name)|psi-mi:GEMIN2(display_short)|uniprotkb:SIP1(gene name synonym)|uniprotkb:Component of gems 2(gene name synonym)|uniprotkb:Survival of motor neuron protein-interacting protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000092208(gene)|ensembl:ENST00000250379(transcript)|ensembl:ENST00000308317(transcript)|ensembl:ENST00000396249(transcript)|ensembl:ENST00000412033(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR017364(Survival of motor neuron protein interacting, gemin2)|interpro:IPR035426|mint:O14893|rcsb pdb:2LEH|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|refseq:NP_001009182.1|refseq:NP_001009183.1|refseq:NP_003607.1|dip:DIP-32605N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:cCbpiHhHdfq+SNoIud5xipHgYVA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P06396-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10963392|ensembl:ENSP00000404226|ensembl:ENSP00000362929 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p06396-2(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:AGEL(gene name synonym)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:Cytoplasmic(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENST00000373823(transcript)|ensembl:ENST00000432226(transcript)|ensembl:ENSG00000148180(gene)|intact:EBI-351506(isoform-parent)|uniprotkb:P06396-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:1a/0CWQEYaIdPArQyk4RPyDJTYQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P50395 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P23378 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2509907|ensembl:ENSP00000370737|uniprotkb:Q2M2F8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gcsp_human(display_long)|uniprotkb:GLDC(gene name)|psi-mi:GLDC(display_short)|uniprotkb:GCSP(gene name synonym)|uniprotkb:Glycine decarboxylase(gene name synonym)|uniprotkb:Glycine cleavage system P protein(gene name synonym)|uniprotkb:"Glycine dehydrogenase (aminomethyl-transferring)"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000178445(gene)|ensembl:ENST00000321612(transcript)|go:"GO:0004375"("glycine dehydrogenase (decarboxylating) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016829"(lyase activity)|go:"GO:0019464"(glycine decarboxylation via glycine cleavage system)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0036255"(response to methylamine)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070280"(pyridoxal binding)|go:"GO:1903442"(response to lipoic acid)|interpro:IPR001597(Aromatic amino acid beta-eliminating lyase/threonine aldolase)|interpro:IPR003437(Glycine cleavage system P-protein)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020581|rcsb pdb:6I33|rcsb pdb:6I34|rcsb pdb:6I35|reactome:R-HSA-6783984|refseq:NP_000161.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zNBF42twnLftxt9dEQsTcGD5dts9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P62879 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356942|uniprotkb:P54312|uniprotkb:P11016|uniprotkb:B3KPU1|ensembl:ENSP00000305260|ensembl:ENSP00000377501|ensembl:ENSP00000377503 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gbb2_human(display_long)|uniprotkb:GNB2(gene name)|psi-mi:GNB2(display_short)|uniprotkb:Transducin beta chain 2(gene name synonym)|uniprotkb:G protein subunit beta-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005264.2|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031982"(vesicle)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62879|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|go:"GO:0016020"(membrane)|ensembl:ENSG00000172354(gene)|ensembl:ENST00000303210(transcript)|ensembl:ENST00000393924(transcript)|ensembl:ENST00000393926(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:dingPUxdpAhe7UMLquv0eqXNtUM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P62873 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357130|ensembl:ENSP00000367872|ensembl:ENSP00000481878|uniprotkb:P04901|uniprotkb:P04697|uniprotkb:B1AJZ7|uniprotkb:Q1RMY8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gbb1_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62873|rcsb pdb:4KFM|rcsb pdb:4PNK|rcsb pdb:5HE0|rcsb pdb:5HE1|rcsb pdb:5HE2|rcsb pdb:5HE3|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UKM|rcsb pdb:5UZ7|rcsb pdb:6B3J|rcsb pdb:6CRK|rcsb pdb:6D9H|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6E3Y|rcsb pdb:6EG8|rcsb pdb:6G79|rcsb pdb:6GDG|rcsb pdb:6KPF|rcsb pdb:6KPG|go:"GO:1903561"(extracellular vesicle)|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6M8S|rcsb pdb:6N4B|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6OIJ|rcsb pdb:6OIK|rcsb pdb:6OMM|rcsb pdb:6ORV|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VMS|rcsb pdb:6VN7|rcsb pdb:6WHA|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:6XOX|rcsb pdb:7AUE|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX4|rcsb pdb:7D76|rcsb pdb:7D77|rcsb pdb:7D7M|rcsb pdb:7DFL|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7E9H|rcsb pdb:7CX3|rcsb pdb:7EB2|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7JVR|rcsb pdb:7K7L|rcsb pdb:7K7Z|rcsb pdb:7KH0|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7L1U|rcsb pdb:7L1V|rcsb pdb:7LCI|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-381676|reactome:R-HSA-381753|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|ensembl:ENST00000610897(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097381"(photoreceptor disc membrane)|ensembl:ENSG00000078369(gene)|ensembl:ENST00000378609(transcript)|refseq:NP_001269467.1|refseq:NP_001269468.1|dip:DIP-599N|refseq:NP_002065.1|refseq:XP_016856548.1|refseq:XP_016856549.1|refseq:XP_016856550.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zP/G70MXiSQpzbyyWFTWrJFQENk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14697-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399534|ensembl:ENSP00000340466 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q14697-2(display_long)|uniprotkb:Alpha-glucosidase 2(gene name synonym)|uniprotkb:Glucosidase II subunit alpha(gene name synonym)|uniprotkb:GANAB(gene name)|psi-mi:GANAB(display_short)|uniprotkb:G2AN(gene name synonym)|uniprotkb:KIAA0088(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000089597(gene)|ensembl:ENST00000346178(transcript)|uniprotkb:Q14697-2(isoform-parent)|intact:EBI-348004(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zTzlTLrzu7E/1PCkr9att27x0OY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14976 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-714707|uniprotkb:Q9BVY6|uniprotkb:Q5U4P5|intact:EBI-28970318|ensembl:ENSP00000314499 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:gak_human(display_long)|uniprotkb:GAK(gene name)|psi-mi:GAK(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000314499|ensembl:ENST00000511163|ensembl:ENSP00000421361|refseq:NP_005246.2|refseq:NP_001305063.1|ensembl:ENSG00000178950(gene)|ensembl:ENST00000314167(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0030276"(clathrin binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031982"(vesicle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905224"(clathrin-coated pit assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR035892|interpro:IPR036869|rcsb pdb:4C57|rcsb pdb:4C58|rcsb pdb:4C59|rcsb pdb:4O38|rcsb pdb:4Y8D|rcsb pdb:5Y7Z|rcsb pdb:5Y80|reactome:R-HSA-432722|reactome:R-HSA-8856828|go:"GO:0072318"(clathrin coat disassembly) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:+CTVzAL9y1B3+JIg6PHsj8QXIjE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P04406 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UN86 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|ensembl:ENSP00000352738|ensembl:ENSP00000379069|ensembl:ENSP00000503228|ensembl:ENSP00000503239|ensembl:ENSP00000503355|ensembl:ENSP00000503669|ensembl:ENSP00000503911|ensembl:ENSP00000503943|ensembl:ENSP00000504101|ensembl:ENSP00000504159|ensembl:ENSP00000504316|ensembl:ENSP00000504361|ensembl:ENSP00000504371|ensembl:ENSP00000504496|ensembl:ENSP00000504523|ensembl:ENSP00000504585|ensembl:ENSP00000504698|ensembl:ENSP00000503504|uniprotkb:A8K6X1 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|ensembl:ENSG00000138757(gene)|ensembl:ENST00000677620(transcript)|ensembl:ENST00000678062(transcript)|ensembl:ENST00000678100(transcript)|ensembl:ENST00000678123(transcript)|ensembl:ENST00000678265(transcript)|ensembl:ENST00000678578(transcript)|ensembl:ENST00000678798(transcript)|ensembl:ENST00000678971(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR034377|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|ensembl:ENST00000359707(transcript)|ensembl:ENST00000395719(transcript)|ensembl:ENST00000676584(transcript)|ensembl:ENST00000676974(transcript)|ensembl:ENST00000677162(transcript)|ensembl:ENST00000677171(transcript)|ensembl:ENST00000677201(transcript)|ensembl:ENST00000677333(transcript)|ensembl:ENST00000677566(transcript)|ensembl:ENST00000677606(transcript)|refseq:XP_011530743.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13283 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P51114 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000114416(gene)|ensembl:ENST00000357559(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|go:"GO:0014069"(postsynaptic density)|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|mint:P51114|dip:DIP-40789N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P35637-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-400448|ensembl:ENSP00000369594 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p35637-2(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-400434(fus_human)|ensembl:ENSG00000089280(gene)|ensembl:ENST00000380244(transcript)|uniprotkb:P35637-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:0zs/kr6sg2tiOiKClOdclacymiM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P07954-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399529 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p07954-2(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1050358(isoform-parent) - - isoform-comment:Initiator Met-1 is removed. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:J289hL0nE3jKiix0tdSbEOTxx3g9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92945 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003676.2|ensembl:ENSG00000088247(gene)|ensembl:ENST00000398148(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:hlybJllTqSgPgtwwz3kc12zDYh49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P15328 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2556557|uniprotkb:Q9UCT2|uniprotkb:Q6FGT8|uniprotkb:Q6LC90|uniprotkb:Q53EW2|ensembl:ENSP00000308137|ensembl:ENSP00000377281|ensembl:ENSP00000377284|ensembl:ENSP00000377286|ensembl:ENSP00000502440 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:folr1_human(display_long)|uniprotkb:FOLR(gene name synonym)|uniprotkb:Folate receptor 1(gene name synonym)|uniprotkb:Folate receptor, adult(gene name synonym)|uniprotkb:Adult folate-binding protein(gene name synonym)|uniprotkb:Ovarian tumor-associated antigen MOv18(gene name synonym)|uniprotkb:KB cells FBP(gene name synonym)|uniprotkb:FOLR1(gene name)|psi-mi:FOLR1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000793.1|refseq:NP_057936.1|refseq:NP_057937.1|refseq:NP_057941.1|ensembl:ENST00000675784(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001947"(heart looping)|go:"GO:0003147"(neural crest cell migration involved in heart formation)|go:"GO:0003253"(cardiac neural crest cell migration involved in outflow tract morphogenesis)|go:"GO:0005542"(folic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015884"(folic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030133"(transport vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|ensembl:ENSG00000110195(gene)|ensembl:ENST00000312293(transcript)|ensembl:ENST00000393676(transcript)|ensembl:ENST00000393679(transcript)|go:"GO:0031103"(axon regeneration)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0051870"(methotrexate binding)|ensembl:ENST00000393681(transcript)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0061713"(anterior neural tube closure)|go:"GO:0061714"(folic acid receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071231"(cellular response to folic acid)|go:"GO:1904447"(folate import across plasma membrane)|interpro:IPR004269(Folate receptor)|interpro:IPR018143|interpro:IPR032935|rcsb pdb:4KM6|rcsb pdb:4KM7|rcsb pdb:4KMX|rcsb pdb:4LRH|rcsb pdb:5IZQ|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|go:"GO:0060828"(regulation of canonical Wnt signaling pathway) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:GsZqF+nVBlrPC+7apIMAxbpR6v89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9H479 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-968410|ensembl:ENSP00000300784 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:fn3k_human(display_long)|uniprotkb:FN3K(gene name)|psi-mi:FN3K(display_short)|uniprotkb:Protein-psicosamine 3-kinase FN3K(gene name synonym)|uniprotkb:Protein-ribulosamine 3-kinase FN3K(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000167363(gene)|ensembl:ENST00000300784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0030389"(fructosamine metabolic process)|go:"GO:0030393"(fructoselysine metabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036525"(protein deglycation)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0102193"(protein-ribulosamine 3-kinase activity)|go:"GO:0102194"(protein-fructosamine 3-kinase activity)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016477(Ketosamine-3-kinase)|reactome:R-HSA-163841|refseq:NP_071441.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:mRMfQGYb7f1tdgUDHp64Lyy04DI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q06787-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399524 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q06787-3(display_long)|uniprotkb:Fragile X mental retardation protein 1(gene name synonym)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-366305(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:bVoKq4O4ZgdqSXOiWi0MfSCELiw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96PY5-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11065681|ensembl:ENSP00000288670 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96py5-3(display_long)|uniprotkb:FHOD2(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 2(gene name synonym)|uniprotkb:KIAA1902(gene name synonym)|uniprotkb:FMNL2(gene name)|psi-mi:FMNL2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-3438448(isoform-parent)|ensembl:ENSG00000157827(gene)|ensembl:ENST00000288670(transcript)|uniprotkb:Q96PY5-3(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pM4fJ6ca6OojxErASAodFV6DyUs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14254 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-348613|ensembl:ENSP00000378368 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:flot2_human(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short)|uniprotkb:ESA1(gene name synonym)|uniprotkb:M17S1(gene name synonym)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004466.2|ensembl:ENSG00000132589(gene)|go:"GO:0008544"(epidermis development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|ensembl:ENST00000394908(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001931"(uropod)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|mint:Q14254|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:XP_016879883.1|refseq:XP_016879884.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:P9htlLzTYk+eDKKesqCEPe/1BJA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75955 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-603643|ensembl:ENSP00000365569|ensembl:ENSP00000372873|ensembl:ENSP00000373056|ensembl:ENSP00000388861|ensembl:ENSP00000391438|uniprotkb:Q969J8|uniprotkb:Q9UHW1|uniprotkb:Q9UNV8|uniprotkb:B4DVY7 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:flot1_human(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:O75955|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000137312(gene)|ensembl:ENSG00000206379(gene)|ensembl:ENSG00000206480(gene)|ensembl:ENSG00000230143(gene)|ensembl:ENSG00000232280(gene)|ensembl:ENST00000376389(transcript)|ensembl:ENST00000383382(transcript)|ensembl:ENST00000383562(transcript)|ensembl:ENST00000436822(transcript)|ensembl:ENST00000444632(transcript)|refseq:NP_005794.1|refseq:NP_001305804.1|refseq:XP_005248837.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:wRw9QYIRNJb0ZQtwjm/D+ydci8k9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13045-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11030074|ensembl:ENSP00000438536|ensembl:ENSP00000492392 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q13045-2(display_long)|uniprotkb:FLII(gene name)|psi-mi:FLII(display_short)|uniprotkb:FLIL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000177731(gene)|ensembl:ENSG00000284571(gene)|ensembl:ENST00000545457(transcript)|ensembl:ENST00000638404(transcript)|intact:EBI-351549(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:u72oQX+8+d9FLf7oxWtHw9X8WoI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P37268 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-714550|intact:EBI-1058542|uniprotkb:Q96GT0|ensembl:ENSP00000220584|ensembl:ENSP00000480828|ensembl:ENSP00000481481|uniprotkb:B3KQ95|uniprotkb:B4DJE5|uniprotkb:B4DT56|uniprotkb:B7Z1J3 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:fdft_human(display_long)|uniprotkb:Farnesyl-diphosphate farnesyltransferase(gene name synonym)|uniprotkb:"FPP:FPP farnesyltransferase"(gene name synonym)|uniprotkb:FDFT1(gene name)|psi-mi:FDFT1(display_short)|uniprotkb:Farnesyl-diphosphate farnesyltransferase 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENST00000618539(transcript)|refseq:NP_004453.3|ensembl:ENSG00000079459(gene)|ensembl:ENST00000220584(transcript)|ensembl:ENST00000615631(transcript)|rcsb pdb:3LEE|rcsb pdb:3Q2Z|rcsb pdb:3Q30|rcsb pdb:3V66|rcsb pdb:3VJ8|rcsb pdb:3VJ9|rcsb pdb:3VJA|rcsb pdb:3VJB|rcsb pdb:3VJC|rcsb pdb:3WC9|rcsb pdb:3WCD|rcsb pdb:3WCF|rcsb pdb:3WCH|rcsb pdb:3WCI|rcsb pdb:3WCJ|rcsb pdb:3WCL|rcsb pdb:3WCM|rcsb pdb:3WEF|rcsb pdb:3WEG|rcsb pdb:3WEH|rcsb pdb:3WEI|rcsb pdb:3WEJ|rcsb pdb:3WEK|rcsb pdb:3WSA|rcsb pdb:6PYJ|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|rcsb pdb:3ASX|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0004310"(farnesyl-diphosphate farnesyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045338"(farnesyl diphosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051996"(squalene synthase activity)|interpro:IPR002060(Squalene/phytoene synthase)|interpro:IPR006449(Farnesyl-diphosphate farnesyltransferase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR019845|interpro:IPR033904|interpro:IPR044844|mint:P37268|rcsb pdb:1EZF|refseq:NP_001274671.1|refseq:NP_001274672.1|refseq:NP_001274673.1|refseq:NP_001274674.1|refseq:NP_001274676.1|refseq:NP_001274677.1|refseq:NP_001274678.1|refseq:NP_001274679.1|refseq:NP_001274680.1|refseq:NP_001274685.1|refseq:XP_016868706.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3TjanjXw3X58/ZOEsB1xczV0/qQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q0JRZ9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2609756|uniprotkb:Q0JTJ3|uniprotkb:B2RNQ9|uniprotkb:A8K6W7|uniprotkb:Q96CF5|ensembl:ENSP00000393776|uniprotkb:B4DHK0|uniprotkb:E9PG79 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:fcho2_human(display_long)|uniprotkb:FCHO2(gene name)|psi-mi:FCHO2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001139504.1|refseq:NP_620137.2|ensembl:ENST00000430046(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0010324"(membrane invagination)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098835"(presynaptic endocytic zone membrane)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR018808|interpro:IPR027267|interpro:IPR028565|interpro:IPR030122|interpro:IPR031160|rcsb pdb:2V0O|reactome:R-HSA-8856825|reactome:R-HSA-8856828|ensembl:ENSG00000157107(gene)|dip:DIP-29488N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:JYPt0L04ZvoacrpUFy49uFWxD489606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8NEZ5-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399518|ensembl:ENSP00000396442 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q8nez5-3(display_long)|uniprotkb:F-box protein FBX22p44(gene name synonym)|uniprotkb:FBXO22(gene name)|psi-mi:FBXO22(display_short)|uniprotkb:FBX22(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000167196(gene)|ensembl:ENST00000453211(transcript)|intact:EBI-2510137(isoform-parent)|uniprotkb:Q8NEZ5-3(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:iQO51dfIfHMiOK24z/Po+rIzm2U9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96JY6-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399808 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96jy6-3(display_long)|uniprotkb:PDLIM2(gene name)|psi-mi:PDLIM2(display_short)|uniprotkb:PP6345(orf name)|uniprotkb:Mystique 1(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 uniprotkb:Q96JY6(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:n7Uw7BTEHgCA4nvXZp1Nrl7PD/E9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00151 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-724897|uniprotkb:Q5VZH5|uniprotkb:Q9BPZ9|uniprotkb:B2RBS6|ensembl:ENSP00000360305 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pdli1_human(display_long)|uniprotkb:Elfin(gene name synonym)|uniprotkb:LIM domain protein CLP-36(gene name synonym)|uniprotkb:C-terminal LIM domain protein 1(gene name synonym)|uniprotkb:PDLIM1(gene name)|psi-mi:PDLIM1(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:CLP36(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_066272.1|go:"GO:0003779"(actin binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031941"(filamentous actin)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|ensembl:ENSG00000107438(gene)|interpro:IPR006643(ZASP)|interpro:IPR028537|interpro:IPR031847|interpro:IPR036034|rcsb pdb:1X62|rcsb pdb:2PKT|ensembl:ENST00000329399(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001725"(stress fiber)|go:"GO:0003713"(transcription coactivator activity) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:kUUqX2NgmaXbdbESj6oHxE+EQ2g9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y2S7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P07237 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P49585 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2563309|uniprotkb:Q86Y88|uniprotkb:A9LYK9|uniprotkb:D3DXB1|ensembl:ENSP00000292823|ensembl:ENSP00000394617 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pcy1a_human(display_long)|uniprotkb:PCYT1A(gene name)|psi-mi:PCYT1A(display_short)|uniprotkb:CTPCT(gene name synonym)|uniprotkb:PCYT1(gene name synonym)|uniprotkb:Phosphorylcholine transferase A(gene name synonym)|uniprotkb:"CTP:phosphocholine cytidylyltransferase A"(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005008.2|refseq:NP_001299602.1|ensembl:ENSG00000161217(gene)|ensembl:ENST00000292823(transcript)|ensembl:ENST00000431016(transcript)|go:"GO:0004105"(choline-phosphate cytidylyltransferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR041723|mint:P49585|reactome:R-HSA-1483191 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:64kROfRkpFhQ9iL46Q8WetwqBFg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y365 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-4289836|uniprotkb:O60532|ensembl:ENSP00000335247|ensembl:ENSP00000438792 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:sta10_human(display_long)|uniprotkb:STARD10(gene name)|psi-mi:STARD10(display_short)|uniprotkb:SDCCAG28(gene name synonym)|uniprotkb:Antigen NY-CO-28(gene name synonym)|uniprotkb:Serologically defined colon cancer antigen 28(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 10(gene name synonym)|uniprotkb:CGI-52(orf name)|uniprotkb:PCTP-like protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000214530(gene)|ensembl:ENST00000334805(transcript)|ensembl:ENST00000543304(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0031514"(motile cilium)|go:"GO:0046581"(intercellular canaliculus)|interpro:IPR002913(Lipid-binding START)|interpro:IPR023393|interpro:IPR041951|mint:Q9Y365|rcsb pdb:6SER|reactome:R-HSA-1483191|refseq:NP_006636.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:dT74wCec5ul2kdfqw0RH5axrocM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P12004 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15366-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11073205|ensembl:ENSP00000352438 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q15366-2(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-945799(isoform-parent)|ensembl:ENSG00000197111(gene)|ensembl:ENST00000359462(transcript) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:1s5dGl6tUQb/FDz6bjXQbB3YcO09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15365 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96AQ6-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399873|ensembl:ENSP00000357450 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96aq6-2(display_long)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000163346(gene)|ensembl:ENST00000368465(transcript)|intact:EBI-740845(isoform-parent)|uniprotkb:Q96AQ6-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:mpQaY6xF43AAl8fV9F/9CtgJu2I9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96IZ0 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-595869|uniprotkb:O75796|uniprotkb:Q6FHY9|uniprotkb:Q8N700|intact:EBI-2561293|ensembl:ENSP00000328088 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pawr_human(display_long)|uniprotkb:Prostate apoptosis response 4 protein(gene name synonym)|uniprotkb:PAWR(gene name)|psi-mi:PAWR(display_short)|uniprotkb:PAR4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002574.2|refseq:XP_016874866.1|refseq:XP_006719498.1|dip:DIP-29003N|ensembl:ENSG00000177425(gene)|ensembl:ENST00000328827(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR026117|rcsb pdb:2JK9 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid://McqfeFZjywd7Ew+WWk0eCzfNw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q86TB9-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399867 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q86tb9-2(display_long)|uniprotkb:PAT1-like protein 1(gene name synonym)|uniprotkb:Protein PAT1 homolog b(gene name synonym)|uniprotkb:OK/KNS-cl.5(orf name)|uniprotkb:PATL1(gene name)|psi-mi:PATL1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-2562092(isoform-parent)|uniprotkb:Q86TB9-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:i1K0MpQss2Q+0a62IHySNdxxomw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:A6NDB9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-6873185|intact:EBI-28977450|ensembl:ENSP00000344996|ensembl:ENSP00000500424 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:palm3_human(display_long)|uniprotkb:PALM3(gene name)|psi-mi:PALM3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000344996|ensembl:ENSP00000500424|ensembl:ENSG00000187867(gene)|ensembl:ENSG00000288318(gene)|ensembl:ENST00000340790(transcript)|ensembl:ENST00000672551(transcript)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|interpro:IPR024149|refseq:NP_001138500.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:PzFwi9b2OsyYZVc5nVVWWCFiBvY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75781-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399860|ensembl:ENSP00000264560 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o75781-2(display_long)|uniprotkb:Paralemmin(gene name synonym)|uniprotkb:Paralemmin-S(isoform synonym)|uniprotkb:PALM(gene name)|psi-mi:PALM(display_short)|uniprotkb:KIAA0270(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000099864(gene)|ensembl:ENST00000264560(transcript)|intact:EBI-6448827(isoform-parent)|uniprotkb:O75781-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:X4mzLMXzt4agUAqjC7umyX5+PcM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UNF0 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000385040|ensembl:ENSP00000385372|ensembl:ENSP00000263246 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|refseq:XP_016884053.1|ensembl:ENST00000263246(transcript)|ensembl:ENST00000402229(transcript)|ensembl:ENST00000403744(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000100266(gene)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070836"(caveola assembly)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028521|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P11940-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399852 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p11940-2(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-81531(isoform-parent)|uniprotkb:P11940-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:xCbtQrva6ZxuEk+UaSEo0siM6bw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00443 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-641094|ensembl:ENSP00000265970|uniprotkb:Q14CQ9|uniprotkb:B4E2G4|uniprotkb:B0LPH2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p3c2a_human(display_long)|uniprotkb:Phosphoinositide 3-kinase-C2-alpha(gene name synonym)|uniprotkb:PIK3C2A(gene name)|psi-mi:PIK3C2A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000011405(gene)|ensembl:ENST00000265970(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0016020"(membrane)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0006887"(exocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|refseq:NP_001308307.1|refseq:XP_016873413.1|refseq:NP_002636.2|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0061024"(membrane organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR001683(Phox-like)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036871|interpro:IPR036940|interpro:IPR037705|interpro:IPR042133|interpro:IPR042236|rcsb pdb:2AR5|rcsb pdb:2IWL|rcsb pdb:2REA|rcsb pdb:2RED|rcsb pdb:6BTY|rcsb pdb:6BTZ|rcsb pdb:6BU0|rcsb pdb:6BUB|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-432722|reactome:R-HSA-8856828|dip:DIP-33727N|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:etm4OwWiGBZtmarHi94o8yW9js89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BZF1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399844 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9bzf1-2(display_long)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)|uniprotkb:KIAA1451(gene name synonym)|uniprotkb:ORP8(gene name synonym)|uniprotkb:OSBP10(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-2684038(isoform-parent)|uniprotkb:Q9BZF1-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:IMEp20buriOXUP2fsqF2DSUieRo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NTK5 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-766468|uniprotkb:Q5BJD7|uniprotkb:Q8NCI8|uniprotkb:Q96CU1|uniprotkb:Q96SV2|uniprotkb:Q9P1D3|uniprotkb:Q9UNY9|uniprotkb:Q9Y6G4|uniprotkb:D7EHM2|ensembl:ENSP00000284719 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ola1_human(display_long)|uniprotkb:GTPBP9(gene name synonym)|uniprotkb:GTP-binding protein 9(gene name synonym)|uniprotkb:OLA1(gene name)|psi-mi:OLA1(display_short)|uniprotkb:PTD004(orf name)|uniprotkb:PRO2455(orf name)|uniprotkb:DNA damage-regulated overexpressed in cancer 45(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001011708.1|refseq:NP_037473.3|dip:DIP-34591N|ensembl:ENST00000284719(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004095(TGS)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR023192|interpro:IPR027417|interpro:IPR031167|interpro:IPR041706|mint:Q9NTK5|rcsb pdb:2OHF|reactome:R-HSA-114608|ensembl:ENSG00000138430(gene) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:aQk5XBcKpx1YSW4mHtyRsTpimvk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O15294 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-539828|uniprotkb:Q7Z3K0|uniprotkb:Q8WWM8|uniprotkb:Q96CC1|uniprotkb:Q9UG57|ensembl:ENSP00000362824 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ogt1_human(display_long)|uniprotkb:O-linked N-acetylglucosamine transferase 110 kDa subunit(gene name synonym)|uniprotkb:O-GlcNAc transferase subunit p110(gene name synonym)|uniprotkb:OGT(gene name)|psi-mi:OGT(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_858058.1|refseq:NP_858059.1|rcsb pdb:3PE3|rcsb pdb:3PE4|rcsb pdb:3TAX|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4CDR|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4GZ5|rcsb pdb:4GZ6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:1W3B|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:4XI9|rcsb pdb:4XIF|rcsb pdb:5BNW|rcsb pdb:5C1D|rcsb pdb:5HGV|rcsb pdb:5LVV|rcsb pdb:5LWV|rcsb pdb:5NPR|rcsb pdb:5NPS|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:6E37|rcsb pdb:6EOU|rcsb pdb:6IBO|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|rcsb pdb:6Q4M|rcsb pdb:6TKA|reactome:R-HSA-3214847|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-5689603|rcsb pdb:6MA1|ensembl:ENSG00000147162(gene)|ensembl:ENST00000373719(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016262"(protein N-acetylglucosaminyltransferase activity)|go:"GO:0016485"(protein processing)|go:"GO:0017122"(protein N-acetylglucosaminyltransferase complex)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097363"(protein O-GlcNAc transferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR029489|interpro:IPR037919|mint:O15294|go:"GO:0042995"(cell projection)|refseq:XP_016885396.1|refseq:XP_016885397.1|dip:DIP-33491N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:NmuVFHeg1QRYMbVav6e7fRJft5U9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P08559-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399838|ensembl:ENSP00000438550 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p08559-2(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:PDHA1(gene name)|psi-mi:PDHA1(display_short)|uniprotkb:PHE1A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000131828(gene)|ensembl:ENST00000545074(transcript)|intact:EBI-715747(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:36UydxKJj+eBfuzY98L3L1UJYjg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P36957 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351007|uniprotkb:Q9BQ32|uniprotkb:Q7LDY7|intact:EBI-2511564|uniprotkb:B7Z5W8|uniprotkb:E7ESY5|ensembl:ENSP00000335304 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:odo2_human(display_long)|uniprotkb:DLST(gene name)|psi-mi:DLST(display_short)|uniprotkb:DLTS(gene name synonym)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001924.2|ensembl:ENSG00000119689(gene)|ensembl:ENST00000334220(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:P36957|rcsb pdb:6H05|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:lZLUcTHB/dxXBTI/IXnSjyuVmBo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q01968-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11749425|ensembl:ENSP00000349635 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q01968-2(display_long)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:OCRL1(gene name synonym)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-6148898(isoform-parent)|uniprotkb:Q01968-2(isoform-parent)|ensembl:ENSG00000122126(gene)|ensembl:ENST00000357121(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:TJnAUUPjQFEcQlaIfZ3fq6vaVQU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q16625-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399831|ensembl:ENSP00000504966|ensembl:ENSP00000506305 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q16625-2(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short)|uniprotkb:OCLN-ex4del(isoform synonym)|uniprotkb:"TM4(-)"(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000197822(gene)|ensembl:ENST00000680496(transcript)|ensembl:ENST00000680784(transcript)|intact:EBI-2903088(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Nql9WmI6Pg7/wyF7M00xJarEf8o9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P04181 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-721662|uniprotkb:Q68CS0|uniprotkb:Q16068|uniprotkb:Q16069|uniprotkb:Q9UD03|intact:EBI-1237002|uniprotkb:Q6IAV9|uniprotkb:D3DRF0|ensembl:ENSP00000357838 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:oat_human(display_long)|uniprotkb:Ornithine--oxo-acid aminotransferase(gene name synonym)|uniprotkb:OAT(gene name)|psi-mi:OAT(display_short)|uniprotkb:Ornithine delta-aminotransferase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_000265.1|refseq:NP_001165285.1|refseq:NP_001309894.1|refseq:NP_001309895.1|refseq:NP_001309896.1|refseq:NP_001309897.1|refseq:NP_001309898.1|refseq:NP_001309899.1|refseq:NP_001309900.1|rcsb pdb:6OIA|rcsb pdb:6V8C|rcsb pdb:6V8D|rcsb pdb:7JX9|reactome:R-HSA-8964539|ensembl:ENSG00000065154(gene)|ensembl:ENST00000368845(transcript)|go:"GO:0004587"(ornithine-oxo-acid transaminase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007601"(visual perception)|go:"GO:0010121"(arginine catabolic process to proline via ornithine)|go:"GO:0019544"(arginine catabolic process to glutamate)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0050155"("ornithine(lysine) transaminase activity")|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR010164(Ornithine aminotransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1GBN|rcsb pdb:1OAT|rcsb pdb:2BYJ|rcsb pdb:2BYL|rcsb pdb:2CAN|rcsb pdb:2OAT|rcsb pdb:5VWO|rcsb pdb:6HX7 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:j+e5fOgz5Yv7lLp2NV8Uq+eR6909606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P00973-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-12081862|ensembl:ENSP00000415721 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p00973-2(display_long)|uniprotkb:OAS1(gene name)|psi-mi:OAS1(display_short)|uniprotkb:E18/E16(gene name synonym)|uniprotkb:OIAS(gene name synonym)|uniprotkb:p46/p42 OAS(gene name synonym)|uniprotkb:3-9(isoform synonym)|uniprotkb:41 kDa(isoform synonym)|uniprotkb:E16(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-3932815(isoform-parent)|ensembl:ENSG00000089127(gene)|ensembl:ENST00000452357(transcript)|uniprotkb:P00973-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pmA0VGhDjQ+D4+rdyldFXCtMHGU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q149M9 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-9477336|uniprotkb:Q68CT3|uniprotkb:C9J021|ensembl:ENSP00000447224 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:nwd1_human(display_long)|uniprotkb:NWD1(gene name)|psi-mi:NWD1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001277284.1|refseq:NP_001334923.1|refseq:XP_011526231.1|refseq:XP_011526232.1|refseq:XP_011526233.1|refseq:NP_001007526.3|ensembl:ENSG00000188039(gene)|ensembl:ENST00000552788(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027417|interpro:IPR043365 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Bi9PAyjCPdeoLQWAeyXUlScGNm49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P49757-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10692196|ensembl:ENSP00000352563|ensembl:ENSP00000451117 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p49757-3(display_long)|uniprotkb:C14orf41(gene name synonym)|uniprotkb:NUMB(gene name)|psi-mi:NUMB(display_short)|uniprotkb:Protein S171(gene name synonym)|uniprotkb:p71(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-915016(isoform-parent)|uniprotkb:P49757-3(isoform-parent)|ensembl:ENSG00000133961(gene)|ensembl:ENST00000359560(transcript)|ensembl:ENST00000557597(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:N2YwdjNBMiXeMFYxQrJDxqeNkSA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q7Z417 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9Y266 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-357298|ensembl:ENSP00000319664|uniprotkb:Q5QP31|uniprotkb:Q5QP35|uniprotkb:Q9H0N2|uniprotkb:Q9Y2B6|intact:EBI-2555945 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:nudc_human(display_long)|uniprotkb:NUDC(gene name)|psi-mi:NUDC(display_short)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000090273(gene)|ensembl:ENST00000321265(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:Q9Y266|rcsb pdb:3QOR|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0007080"(mitotic metaphase plate congression)|reactome:R-HSA-9696270|refseq:NP_006591.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:e1Q+/+VhG73ljCc3+ibG+RZNQUM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P19338 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P46459 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P06748 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P55209 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15599-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399825|ensembl:ENSP00000402857 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q15599-2(display_long)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000065054(gene)|ensembl:ENST00000432365(transcript)|intact:EBI-1149760(isoform-parent)|uniprotkb:Q15599-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:GkYJsGvNH2JRijW5tE/vb0Jtmw09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8NFW8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2816175|uniprotkb:Q9NQZ0|uniprotkb:Q96AX5|ensembl:ENSP00000229329 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:neua_human(display_long)|uniprotkb:CMAS(gene name)|psi-mi:CMAS(display_short)|uniprotkb:CMP-N-acetylneuraminic acid synthase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_061156.1|ensembl:ENSG00000111726(gene)|ensembl:ENST00000229329(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006054"(N-acetylneuraminate metabolic process)|go:"GO:0008781"(N-acylneuraminate cytidylyltransferase activity)|go:"GO:0016020"(membrane)|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|interpro:IPR023214|interpro:IPR029044|interpro:IPR036412|mint:Q8NFW8|reactome:R-HSA-4085001 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:N8On3mF4lrgjWtwXAwzmhpUZXn49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8NC96 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2609792|uniprotkb:Q5XG95|uniprotkb:Q8NCB0|uniprotkb:Q9BU52|uniprotkb:Q9Y407|uniprotkb:Q6NWY6|uniprotkb:Q2NL73|uniprotkb:Q8N153|intact:EBI-28972454|ensembl:ENSP00000341737|ensembl:ENSP00000491067 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:necp1_human(display_long)|uniprotkb:NECAP1(gene name)|psi-mi:NECAP1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000341737|ensembl:ENST00000450991|ensembl:ENSP00000401963|ensembl:ENSP00000491067|refseq:NP_056324.2|ensembl:ENSG00000089818(gene)|ensembl:ENST00000339754(transcript)|ensembl:ENST00000639955(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|rcsb pdb:6RH5|rcsb pdb:6RH6|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:g4gtP7dIg26Z0Tf8r89sx949TCs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96SB3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351275|uniprotkb:Q8TCR9|intact:EBI-28984643|ensembl:ENSP00000478767|intact:EBI-4401886|uniprotkb:D3DTX6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:neb2_human(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:PPP1R9B(gene name)|psi-mi:PPP1R9B(display_short)|uniprotkb:PPP1R6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000108819(gene)|ensembl:ENST00000612501(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0001560"(regulation of cell growth by extracellular stimulus)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031175"(neuron projection development)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035094"(response to nicotine)|go:"GO:0035690"|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060179"(male mating behavior)|go:"GO:0061458"(reproductive system development)|go:"GO:0071315"(cellular response to morphine)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097338"(response to clozapine)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903119"(protein localization to actin cytoskeleton)|go:"GO:1904372"(positive regulation of protein localization to actin cortical patch)|go:"GO:1904373"(response to kainic acid)|go:"GO:1904386"(response to L-phenylalanine derivative)|go:"GO:1990778"(protein localization to cell periphery)|go:"GO:1990780"(cytoplasmic side of dendritic spine plasma membrane)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029921|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q96SB3|ensembl:ENSP00000478767|refseq:NP_115984.3 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:X6fQLpaYhXCqzRlQNEoX67P/HbU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O75306 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q09161 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UJ70-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11526455|ensembl:ENSP00000389087|ensembl:ENSP00000477639 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9uj70-2(display_long)|uniprotkb:GlcNAc kinase(gene name synonym)|uniprotkb:NAGK(gene name)|psi-mi:NAGK(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-372578(isoform-parent)|ensembl:ENSG00000124357(gene)|ensembl:ENST00000455662(transcript)|ensembl:ENST00000613852(transcript)|uniprotkb:Q9UJ70-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zoy4C+HK341UnmDRUlMuJucczr89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q15274 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-739851|uniprotkb:Q53XW7|uniprotkb:Q96G22|uniprotkb:Q9BSG6|ensembl:ENSP00000378782|ensembl:ENSP00000404873 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:nadc_human(display_long)|uniprotkb:QPRT(gene name)|psi-mi:QPRT(display_short)|uniprotkb:Quinolinate phosphoribosyltransferase [decarboxylating](gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_055113.2|refseq:NP_001305178.1|refseq:NP_001305179.1|ensembl:ENSG00000103485(gene)|ensembl:ENST00000395384(transcript)|ensembl:ENST00000449759(transcript)|go:"GO:0004514"("nicotinate-nucleotide diphosphorylase (carboxylating) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0034213"(quinolinate catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902494"(catalytic complex)|interpro:IPR002638(Quinolinate phosphoribosyl transferase)|interpro:IPR004393(Nicotinate-nucleotide pyrophosphorylase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR022412|interpro:IPR027277|interpro:IPR036068|interpro:IPR037128|rcsb pdb:2JBM|rcsb pdb:4KWV|rcsb pdb:4KWW|rcsb pdb:5AYX|rcsb pdb:5AYY|rcsb pdb:5AYZ|reactome:R-HSA-196807 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ayjZsjJprp+eirEIN5VqDHmIzoA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q13765 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-712216|ensembl:ENSP00000349212|ensembl:ENSP00000377469|ensembl:ENSP00000446801|ensembl:ENSP00000447821|ensembl:ENSP00000503345|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|uniprotkb:F8VU71 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000196531(gene)|ensembl:ENST00000356769(transcript)|ensembl:ENST00000393891(transcript)|ensembl:ENST00000546392(transcript)|ensembl:ENST00000552540(transcript)|ensembl:ENST00000678066(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006412"(translation)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0015031"(protein transport)|go:"GO:0042060"(wound healing)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901227"(negative regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|go:"GO:0043403"(skeletal muscle tissue regeneration)|refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14974 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351726|uniprotkb:Q2NKL4|uniprotkb:Q569H0|uniprotkb:Q86WU3|uniprotkb:Q8NFR6|uniprotkb:Q9BYH0|intact:EBI-28988491|uniprotkb:B4DZ09|uniprotkb:F8VWB4|ensembl:ENSP00000261207|ensembl:ENSP00000389168 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mypt1_human(display_long)|uniprotkb:PPP1R12A(gene name)|psi-mi:PPP1R12A(display_short)|uniprotkb:MBS(gene name synonym)|uniprotkb:MYPT1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001137357.1|refseq:NP_001137358.1|refseq:NP_002471.1|refseq:NP_001231919.1|refseq:NP_001231921.1|refseq:XP_011536685.1|ensembl:ENSP00000261207|ensembl:ENST00000437004|ensembl:ENSP00000416769|ensembl:ENSP00000389168|ensembl:ENSP00000449514|ensembl:ENST00000550107|ensembl:ENSP00000446855|ensembl:ENST00000546369|dip:DIP-33186N|ensembl:ENSG00000058272(gene)|ensembl:ENST00000261207(transcript)|ensembl:ENST00000450142(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031775|interpro:IPR036770|mint:O14974|rcsb pdb:2KJY|rcsb pdb:5HUZ|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Xi5lGskc0tWQCHtbYlgR45ERMSk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NZM1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399816 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9nzm1-2(display_long)|uniprotkb:Fer-1-like protein 3(gene name synonym)|uniprotkb:MYOF(gene name)|psi-mi:MYOF(display_short)|uniprotkb:FER1L3(gene name synonym)|uniprotkb:KIAA1207(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1994363(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:gkN4J5emKxff+qTmTow+UKQ/cY89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UM54-1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-15706115|ensembl:ENSP00000358994 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9um54-1(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000196586(gene)|ensembl:ENST00000369977(transcript)|intact:EBI-350606(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:uFMPpQEidjVNolsax1gFVpfAVUQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O94832 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355634|uniprotkb:Q8NHP9|ensembl:ENSP00000324527|uniprotkb:A6H8V3 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:myo1d_human(display_long)|uniprotkb:MYO1D(gene name)|psi-mi:MYO1D(display_short)|uniprotkb:KIAA0727(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_056009.1|ensembl:ENSG00000176658(gene)|ensembl:ENST00000318217(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030424"(axon)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051641"(cellular localization)|go:"GO:0061502"(early endosome to recycling endosome transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097440"(apical dendrite)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001290208.1|interpro:IPR036961 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:EjrnXi04BVb6Z59cU3e5LW7EhRI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O43795-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965344|ensembl:ENSP00000341903 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o43795-2(display_long)|uniprotkb:MYO1B(gene name)|psi-mi:MYO1B(display_short)|uniprotkb:MYH-1c(gene name synonym)|uniprotkb:Myosin I alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000128641(gene)|ensembl:ENST00000339514(transcript)|intact:EBI-351119(isoform-parent)|uniprotkb:O43795-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:avuE8ro9RvQtGz61qVPLTPZXfDY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P60660-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-11029962|ensembl:ENSP00000446714|uniprotkb:P24572-2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p60660-2(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:17 kDa myosin light chain(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:LC17-sm(isoform synonym)|uniprotkb:LC17B(isoform synonym)|uniprotkb:MLC3sm(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000092841(gene)|ensembl:ENST00000547649(transcript)|intact:EBI-300817(isoform-parent)|uniprotkb:P60660-2(isoform-parent) - - isoform-comment:Contains a phosphoserine at position 135. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:kNgBsqzKYhd3tnQp2PYREseytiY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P35579 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q92614-4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10977809|ensembl:ENSP00000434228 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q92614-4(display_long)|uniprotkb:MYO18A(gene name)|psi-mi:MYO18A(display_short)|uniprotkb:KIAA0216(gene name synonym)|uniprotkb:MYSPDZ(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:CD245(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000196535(gene)|ensembl:ENST00000531253(transcript)|intact:EBI-949059(isoform-parent)|uniprotkb:Q92614-4(isoform-parent) - - isoform-comment:No experimental confirmation available. Contains a phosphoserine at position 1959. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:zcTPBa9xF6ftRMeF/wgZj4WBQXM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14764 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977|ensembl:ENSP00000378760 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSP00000349977|ensembl:ENSP00000378760|refseq:NP_001280133.1|refseq:NP_001280134.1|refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364(gene)|ensembl:ENST00000357402(transcript)|ensembl:ENST00000395353(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q5JR59 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-742948|ensembl:ENSP00000483729|uniprotkb:O94872|uniprotkb:Q08E97|uniprotkb:Q5JQR3|uniprotkb:Q8N5E2|uniprotkb:B4DF81|uniprotkb:A7E292 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mtus2_human(display_long)|uniprotkb:TIP150(gene name synonym)|uniprotkb:MTUS2(gene name)|psi-mi:MTUS2(display_short)|uniprotkb:CAZIP(gene name synonym)|uniprotkb:KIAA0774(gene name synonym)|uniprotkb:Microtubule plus-end tracking protein TIP150(gene name synonym)|uniprotkb:Cardiac zipper protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001028774.2|refseq:NP_056048.1|ensembl:ENSG00000132938(gene)|ensembl:ENST00000612955(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR033339|mint:Q5JR59|ensembl:ENST00000380808|ensembl:ENSP00000370186|ensembl:ENST00000542829|ensembl:ENSP00000445403|ensembl:ENSP00000483729 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:mC6V+TBEtOpFLeNXq09unF0p6N49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9ULD2-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965836|ensembl:ENSP00000371293|ensembl:ENSP00000430167 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9uld2-2(display_long)|uniprotkb:AT2 receptor-binding protein(gene name synonym)|uniprotkb:ATBP(gene name synonym)|uniprotkb:ATIP(gene name synonym)|uniprotkb:Angiotensin-II type 2 receptor-interacting protein(gene name synonym)|uniprotkb:GK1(gene name synonym)|uniprotkb:KIAA1288(gene name synonym)|uniprotkb:MTSG1(gene name synonym)|uniprotkb:Mitochondrial tumor suppressor 1(gene name synonym)|uniprotkb:ATIP3b(isoform synonym)|uniprotkb:MTUS1(gene name)|psi-mi:MTUS1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000129422(gene)|ensembl:ENST00000381869(transcript)|ensembl:ENST00000519263(transcript)|intact:EBI-2818124(isoform-parent)|uniprotkb:Q9ULD2-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ROqTPxMC4JkwjliRmHcF34rYDTw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96DH6-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399707|ensembl:ENSP00000313616 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96dh6-2(display_long)|uniprotkb:MSI2(gene name)|psi-mi:MSI2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-2462339(isoform-parent)|ensembl:ENSG00000153944(gene)|ensembl:ENST00000322684(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Kut4/1wOMPS3cezu5262rVjt9lw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P49006 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-4289961|uniprotkb:Q5TEE6|uniprotkb:Q6NXS5|uniprotkb:D3DPQ0|ensembl:ENSP00000362638 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mrp_human(display_long)|uniprotkb:MARCKSL1(gene name)|psi-mi:MARCKSL1(display_short)|uniprotkb:MLP(gene name synonym)|uniprotkb:MRP(gene name synonym)|uniprotkb:MARCKS-like protein 1(gene name synonym)|uniprotkb:Macrophage myristoylated alanine-rich C kinase substrate(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000175130(gene)|ensembl:ENST00000329421(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P49006|refseq:NP_075385.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:nkq8hGJINvCHlZJ3alKkDP+wCxk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6WCQ1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10965272|ensembl:ENSP00000379156 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q6wcq1-2(display_long)|uniprotkb:MPRIP(gene name)|psi-mi:MPRIP(display_short)|uniprotkb:KIAA0864(gene name synonym)|uniprotkb:MRIP(gene name synonym)|uniprotkb:RHOIP3(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000133030(gene)|ensembl:ENST00000395811(transcript)|intact:EBI-1022605(isoform-parent)|uniprotkb:Q6WCQ1-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:lBw4zzWo+61X7AhdzomRUL4l4nA9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8N3R9-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399750|ensembl:ENSP00000451488 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q8n3r9-2(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MAGUK p55 subfamily member 5(gene name synonym)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Membrane protein, palmitoylated 5(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000072415(gene)|ensembl:ENST00000555925(transcript)|intact:EBI-2513978(isoform-parent)|uniprotkb:Q8N3R9-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:MhpuVKShEKx3C5llGvxUHviB8e49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9HCE1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96EN8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1220583|uniprotkb:Q53GP5|uniprotkb:Q8N3A4|uniprotkb:Q9NWM7|ensembl:ENSP00000261326 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mocos_human(display_long)|uniprotkb:MOCOS(gene name)|psi-mi:MOCOS(display_short)|uniprotkb:Molybdenum cofactor sulfurtransferase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_060417.2|ensembl:ENSG00000075643(gene)|ensembl:ENST00000261326(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0008265"(Mo-molybdopterin cofactor sulfurase activity)|go:"GO:0016829"(lyase activity)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032324"(molybdopterin cofactor biosynthetic process)|go:"GO:0043545"(molybdopterin cofactor metabolic process)|go:"GO:0102867"(molybdenum cofactor sulfurtransferase activity)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR005302(Molybdenum cofactor sulphurase, C-terminal)|interpro:IPR005303(MOSC, N-terminal beta barrel)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR028886|mint:Q96EN8|reactome:R-HSA-947581 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:c1HZVYnnbRSW3olxYNYmtb3S8a09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BU76-4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399744 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9bu76-4(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-742459(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:LlR7k4hhlfJmdgTe6GNdDuXjZ389606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O14950 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q16539-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-4403447|ensembl:ENSP00000229795 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q16539-2(display_long)|uniprotkb:MAPK14(gene name)|psi-mi:MAPK14(display_short)|uniprotkb:CSBP(gene name synonym)|uniprotkb:CSBP1(gene name synonym)|uniprotkb:CSBP2(gene name synonym)|uniprotkb:CSPB1(gene name synonym)|uniprotkb:Cytokine suppressive anti-inflammatory drug-binding protein(gene name synonym)|uniprotkb:MAP kinase MXI2(gene name synonym)|uniprotkb:MAX-interacting protein 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase p38 alpha(gene name synonym)|uniprotkb:SAPK2A(gene name synonym)|uniprotkb:MXI2(gene name synonym)|uniprotkb:Stress-activated protein kinase 2a(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-73946(isoform-parent)|ensembl:ENSG00000112062(gene)|ensembl:ENST00000229795(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:FpUuyu7v2seR6hRNlixYR108O2Y9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P28482 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:odzhd70I/8uWedx0+gF38lhe60I9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8N3F8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1056885|uniprotkb:Q5TI16|uniprotkb:Q7RTP5|uniprotkb:Q8N3N8|uniprotkb:Q9BVL9|uniprotkb:Q9BY92|uniprotkb:Q9UH43|uniprotkb:Q9UH44|uniprotkb:Q9UH45|ensembl:ENSP00000215957 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:milk1_human(display_long)|uniprotkb:MICALL1(gene name)|psi-mi:MICALL1(display_short)|uniprotkb:KIAA1668(gene name synonym)|uniprotkb:MIRAB13(gene name synonym)|uniprotkb:Molecule interacting with Rab13(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_203744.1|ensembl:ENSP00000215957|ensembl:ENSG00000100139(gene)|ensembl:ENST00000215957(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032458"(slow endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR028563|interpro:IPR036872|mint:Q8N3F8|rcsb pdb:2KSP|go:"GO:0045296"(cadherin binding) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:G64P9EtjEfLIVLYkb+w3vCWaT0w9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q08431 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3449497|uniprotkb:Q53FU9|uniprotkb:Q9BTL9|uniprotkb:B2R6M7|uniprotkb:Q7Z3D2|uniprotkb:F5GZN3|ensembl:ENSP00000268150|ensembl:ENSP00000456281 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mfgm_human(display_long)|uniprotkb:MFGE8(gene name)|psi-mi:MFGE8(display_short)|uniprotkb:Breast epithelial antigen BA46(gene name synonym)|uniprotkb:HMFG(gene name synonym)|uniprotkb:MFGM(gene name synonym)|uniprotkb:Milk fat globule-EGF factor 8(gene name synonym)|uniprotkb:SED1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005919.2|refseq:NP_001108086.1|refseq:NP_001297248.1|refseq:NP_001297249.1|refseq:NP_001297250.1|ensembl:ENSG00000140545(gene)|ensembl:ENST00000268150(transcript)|ensembl:ENST00000566497(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007338"(single fertilization)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977225 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:rj2XTJMMYB6NPDRjQX9LSEuF3Qw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9BQA1 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:0q4wunYtHalObC8r1wphhelIpr49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9NPJ6 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P40926 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-721232|uniprotkb:O43682|uniprotkb:B4DE44|uniprotkb:E9PDB2|uniprotkb:A8K414|uniprotkb:B2RE78|ensembl:ENSP00000327070 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mdhm_human(display_long)|uniprotkb:MDH2(gene name)|psi-mi:MDH2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005909.2|refseq:NP_001269332.1|refseq:NP_001269333.1|ensembl:ENSG00000146701(gene)|ensembl:ENST00000315758(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016020"(membrane)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0046554"("malate dehydrogenase (NADP+) activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010097(Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P40926|rcsb pdb:2DFD|rcsb pdb:4WLE|rcsb pdb:4WLF|rcsb pdb:4WLN|rcsb pdb:4WLO|rcsb pdb:4WLU|rcsb pdb:4WLV|reactome:R-HSA-70263|reactome:R-HSA-71403 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Ur2aO+2M7e/ftD8RlhPMHBc8/JU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P40925 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-709625|uniprotkb:B7Z3I7|uniprotkb:Q6I9V0|uniprotkb:B2R5V5|uniprotkb:B4DUN2|uniprotkb:F5H098|ensembl:ENSP00000233114|ensembl:ENSP00000446395 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mdhc_human(display_long)|uniprotkb:Cytosolic malate dehydrogenase(gene name synonym)|uniprotkb:MDH1(gene name)|psi-mi:MDH1(display_short)|uniprotkb:MDHA(gene name synonym)|uniprotkb:Diiodophenylpyruvate reductase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001186040.1|refseq:NP_001186041.1|refseq:NP_005908.1|refseq:NP_001303303.1|ensembl:ENSG00000014641(gene)|ensembl:ENST00000233114(transcript)|ensembl:ENST00000544381(transcript)|go:"GO:0004470"(malic enzyme activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0047860"(diiodophenylpyruvate reductase activity)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010945(Malate dehydrogenase, NAD or NADP)|interpro:IPR011274(Malate dehydrogenase, NAD-dependent, cytosolic)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P40925|reactome:R-HSA-70263 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:SbY7B81CiCRe8tXpVpSdT1sKGOU9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P33992 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-359410|ensembl:ENSP00000216122|uniprotkb:O60785|uniprotkb:Q14578|uniprotkb:Q9BTJ4|uniprotkb:Q9BWL8 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mcm5_human(display_long)|uniprotkb:MCM5(gene name)|psi-mi:MCM5(display_short)|uniprotkb:CDC46(gene name synonym)|uniprotkb:CDC46 homolog(gene name synonym)|uniprotkb:P1-CDC46(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000100297(gene)|ensembl:ENST00000216122(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33992|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_006730.2|reactome:R-HSA-69052|reactome:R-HSA-68962|dip:DIP-27578N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:WjJ4lSpADQFtwT0WnumbRHl/lPw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P25205 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355153|uniprotkb:B4DWW4|uniprotkb:Q92660|uniprotkb:Q9BTR3|uniprotkb:Q9NUE7|ensembl:ENSP00000472940 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:mcm3_human(display_long)|uniprotkb:MCM3(gene name)|psi-mi:MCM3(display_short)|uniprotkb:DNA polymerase alpha holoenzyme-associated protein P1(gene name synonym)|uniprotkb:RLF subunit beta(gene name synonym)|uniprotkb:p102(gene name synonym)|uniprotkb:P1-MCM3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002379.3|refseq:NP_001257401.1|ensembl:ENSG00000112118(gene)|ensembl:ENST00000596288(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005813"(centrosome)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0016020"(membrane)|go:"GO:0042555"(MCM complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P25205|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-31726N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:pKYSPG/QbSyVVJtZamU5lVjgIGo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P43243 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96EH3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2339737|uniprotkb:A4D154|ensembl:ENSP00000419370 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:masu1_human(display_long)|uniprotkb:MALSU1(gene name)|psi-mi:MALSU1(display_short)|uniprotkb:C7orf30(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_612455.1|ensembl:ENSG00000156928(gene)|ensembl:ENST00000466681(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0070130"(negative regulation of mitochondrial translation)|go:"GO:0090071"(negative regulation of ribosome biogenesis)|interpro:IPR004394(Iojap-related protein)|interpro:IPR043519|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:7A5H|rcsb pdb:7A5J|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:LK1PkohSTYCWy9AlTBzno0IbXE89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P29966 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002347.5|ensembl:ENSG00000277443(gene)|ensembl:ENST00000612661(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042585"(germinal vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96T17-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399739|ensembl:ENSP00000368964 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96t17-2(display_long)|uniprotkb:MAP7D2(gene name)|psi-mi:MAP7D2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000184368(gene)|ensembl:ENST00000379643(transcript)|intact:EBI-7850186(isoform-parent)|uniprotkb:Q96T17-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:AtiNYcxvGjDnA5dr9I3SHkwIqfs9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q86V48 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-350467|uniprotkb:Q5TH93|uniprotkb:Q8N4X3|uniprotkb:Q8TEH1|ensembl:ENSP00000303758|ensembl:ENSP00000393460 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:luzp1_human(display_long)|uniprotkb:LUZP1(gene name)|psi-mi:LUZP1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001136018.1|refseq:NP_361013.3|refseq:XP_011540392.1|refseq:XP_011540393.1|ensembl:ENSG00000169641(gene)|ensembl:ENST00000302291(transcript)|ensembl:ENST00000418342(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0021503"(neural fold bending)|go:"GO:0060840"(artery development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026734|mint:Q86V48|refseq:XP_016857741.1|dip:DIP-33113N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:l456S0i3H1z5fv6M4SNkdrls/c49606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P83369 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2626024|uniprotkb:A0AVQ1|uniprotkb:Q7Z7P0|uniprotkb:Q8N975|ensembl:ENSP00000286307 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:lsm11_human(display_long)|uniprotkb:LSM11(gene name)|psi-mi:LSM11(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_775762.1|ensembl:ENSG00000155858(gene)|ensembl:ENST00000286307(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016604"(nuclear body)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034109|interpro:IPR039267|rcsb pdb:6V4X|reactome:R-HSA-111367|reactome:R-HSA-73856|reactome:R-HSA-77588 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:G1rWuaQHAPeHEf3rvzT/XkqvaYk9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8ND56-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399729|ensembl:ENSP00000446271|ensembl:ENSP00000461225 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q8nd56-2(display_long)|uniprotkb:Protein FAM61A(gene name synonym)|uniprotkb:Protein SCD6 homolog(gene name synonym)|uniprotkb:Putative alpha-synuclein-binding protein(gene name synonym)|uniprotkb:RNA-associated protein 55A(gene name synonym)|uniprotkb:"AlphaSNBP(B)"(isoform synonym)|uniprotkb:LSM14A(gene name)|psi-mi:LSM14A(display_short)|uniprotkb:C19orf13(gene name synonym)|uniprotkb:FAM61A(gene name synonym)|uniprotkb:RAP55(gene name synonym)|uniprotkb:RAP55A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1384320(isoform-parent)|uniprotkb:Q8ND56-2(isoform-parent)|ensembl:ENSG00000257103(gene)|ensembl:ENSG00000262860(gene)|ensembl:ENST00000544216(transcript)|ensembl:ENST00000575811(transcript) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:BidlGAk2oRX/Ei0E7AbsMnqcdEE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96AG4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P42704 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q8WWI1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399720 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q8wwi1-2(display_long)|uniprotkb:F-box only protein 20(gene name synonym)|uniprotkb:LOMP(gene name synonym)|uniprotkb:LMO7(gene name)|psi-mi:LMO7(display_short)|uniprotkb:FBX20(gene name synonym)|uniprotkb:FBXO20(gene name synonym)|uniprotkb:KIAA0858(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-350367(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:bBFsbM48q9mVJPsfxln+WdJMoTM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P20700 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-968218|ensembl:ENSP00000261366|uniprotkb:Q3SYN7|uniprotkb:Q96EI6|uniprotkb:B2R6J6 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:lmnb1_human(display_long)|uniprotkb:LMNB1(gene name)|psi-mi:LMNB1(display_short)|uniprotkb:LMN2(gene name synonym)|uniprotkb:LMNB(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000113368(gene)|ensembl:ENST00000261366(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P20700|rcsb pdb:2KPW|go:"GO:0005654"(nucleoplasm)|rcsb pdb:3JT0|rcsb pdb:3TYY|rcsb pdb:3UMN|rcsb pdb:5VVX|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|reactome:R-HSA-2559584|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-4419969|reactome:R-HSA-8862803|reactome:R-HSA-8950505|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_005564.1|dip:DIP-34897N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:ZLv4OS5VSmn3sdXB9IP98YdQ+Iw9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P02545 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UPQ0-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-16399713|ensembl:ENSP00000424645 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9upq0-2(display_long)|uniprotkb:LIMCH1(gene name)|psi-mi:LIMCH1(display_short)|uniprotkb:KIAA1102(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000064042(gene)|ensembl:ENST00000512946(transcript)|intact:EBI-2687222(isoform-parent)|uniprotkb:Q9UPQ0-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:EfsbRMsKEstSOqhaZ2P0rMWS+kY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q9UHB6-4 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10977805|ensembl:ENSP00000378400 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q9uhb6-4(display_long)|uniprotkb:LIMA1(gene name)|psi-mi:LIMA1(display_short)|uniprotkb:EPLIN(gene name synonym)|uniprotkb:Epithelial protein lost in neoplasm(gene name synonym)|uniprotkb:SREBP3(gene name synonym)|uniprotkb:PP624(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000050405(gene)|ensembl:ENST00000394943(transcript)|intact:EBI-351479(isoform-parent)|uniprotkb:Q9UHB6-4(isoform-parent) - - isoform-comment:Produced by alternative splicing. Contains a phosphoserine at position 343. figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:W/vx/oc5V2fxzcfWgcYATKyyD+89606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00214-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-12069522|ensembl:ENSP00000309576|ensembl:ENSP00000431398|ensembl:ENSP00000435460|ensembl:ENSP00000408657 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:o00214-2(display_long)|uniprotkb:LGALS8(gene name)|psi-mi:LGALS8(display_short)|uniprotkb:Po66 carbohydrate-binding protein(gene name synonym)|uniprotkb:Prostate carcinoma tumor antigen 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000116977(gene)|ensembl:ENST00000352231(transcript)|ensembl:ENST00000450372(transcript)|ensembl:ENST00000526589(transcript)|ensembl:ENST00000527974(transcript)|intact:EBI-740058(isoform-parent)|uniprotkb:O00214-2(isoform-parent) - - isoform-comment:"Ref.8 (AAL77076) sequence is in conflict in position: 220:M->T." figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:7X26MEsPRfXZ3GkTd2j34cmfRzo9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P07195 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P00338-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-10195200|ensembl:ENSP00000445175|ensembl:ENSP00000500603 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:p00338-3(display_long)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:PIG19(orf name)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000540430(transcript)|ensembl:ENST00000673007(transcript)|uniprotkb:P00338-3(isoform-parent)|intact:EBI-372327(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:D6W0TxH0yH6hTaZ8MvBh4soTNeY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q14847 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|ensembl:ENSP00000325240|ensembl:ENSP00000392853|uniprotkb:B4DGQ0 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834(gene)|ensembl:ENST00000318008(transcript)|ensembl:ENST00000435347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q14847|rcsb pdb:3I35 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q6PKG0-3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-5280398|ensembl:ENSP00000336721 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q6pkg0-3(display_long)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-1052114(isoform-parent)|ensembl:ENSG00000155506(gene)|ensembl:ENST00000336314(transcript)|uniprotkb:Q6PKG0-3(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:H4FRXRDqg2CWIGzkiEybiqgnG2c9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P42166 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O00515 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2880585|ensembl:ENSP00000375829|uniprotkb:Q96GD8|uniprotkb:O95614 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:lad1_human(display_long)|uniprotkb:LAD1(gene name)|psi-mi:LAD1(display_short)|uniprotkb:LAD(gene name synonym)|uniprotkb:Linear IgA disease antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENST00000391967(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005604"(basement membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR017404(Ladinin 1)|mint:O00515|ensembl:ENSG00000159166(gene)|refseq:NP_005549.2 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:C58/NEfIlDj38lGEIsWtqBNuSis9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P83111 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2878119|ensembl:ENSP00000261893|uniprotkb:P83096 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:lactb_human(display_long)|uniprotkb:LACTB(gene name)|psi-mi:LACTB(display_short)|uniprotkb:MRPL56(gene name synonym)|uniprotkb:UNQ843/PRO1781(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000103642(gene)|ensembl:ENST00000261893(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|refseq:NP_116246.2|refseq:NP_741982.1|refseq:NP_001275514.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:idqlmN9YYs76X8+d8+4LALz5WjM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P05455 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60256 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-724960|uniprotkb:B7ZKZ1|uniprotkb:Q6IAS2|ensembl:ENSP00000268835|uniprotkb:B4E1M8|uniprotkb:E7EMY2|uniprotkb:B4E329 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:kprb_human(display_long)|uniprotkb:41 kDa phosphoribosypyrophosphate synthetase-associated protein(gene name synonym)|uniprotkb:PRPSAP2(gene name)|psi-mi:PRPSAP2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_002758.1|refseq:NP_001230865.1|refseq:NP_001230869.1|refseq:NP_001230870.1|refseq:NP_001230871.1|ensembl:ENSG00000141127(gene)|ensembl:ENST00000268835(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|rcsb pdb:2JI4|refseq:XP_005256782.1|refseq:XP_005256783.1|refseq:XP_005256786.1|refseq:XP_016880354.1|refseq:XP_016880355.1|refseq:XP_016880356.1|refseq:XP_016880360.1|refseq:XP_016880361.1|refseq:XP_016880362.1|refseq:XP_016880363.1|refseq:XP_016880364.1|refseq:XP_016880365.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:6sFkRIePKX0zxDEtLbuXM3gPcFQ9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:P33176 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_004512.1|ensembl:ENSG00000170759(gene)|ensembl:ENST00000302418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-29244N - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:O60870 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2561225|ensembl:ENSP00000368881|uniprotkb:B4DX32 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:kin17_human(display_long)|uniprotkb:BTCD(gene name synonym)|uniprotkb:KIN17(gene name synonym)|uniprotkb:KIN, antigenic determinant of recA protein homolog(gene name synonym)|uniprotkb:Binding to curved DNA(gene name synonym)|uniprotkb:KIN(gene name)|psi-mi:KIN(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000151657(gene)|ensembl:ENST00000379562(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006397"(mRNA processing)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019447|interpro:IPR036236|interpro:IPR037321|interpro:IPR038254|interpro:IPR041330|interpro:IPR041995|rcsb pdb:2CKK|rcsb pdb:2V1N|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-8876725|refseq:NP_036443.1|refseq:XP_011517729.1 - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:U7X9Kz2fa34eHs7/ladH6OcFmQM9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ23 uniprotkb:Q96EY1-2 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-3952284|ensembl:ENSP00000347445|ensembl:ENSP00000479815 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:q96ey1-2(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:HCA57(gene name synonym)|uniprotkb:TID1(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:"Tid-1(S)"(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16398399|imex:IM-25739-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 intact:EBI-356767(isoform-parent)|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000355296(transcript)|ensembl:ENST00000614397(transcript)|uniprotkb:Q96EY1-2(isoform-parent) - - - figure legend:Table 1, Direct submission|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2019/05/28 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:vUs6QuX7N1lqIy87Hp7RaF1+URY9606 rigid:PxQbOhioJvfUaZbK2gR7tbguMmE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKV8 uniprotkb:Q6IQ23 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:0663"(confocal microscopy) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16400496|imex:IM-25739-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0005915"(zonula adherens) - - figure legend:Fig. 1A, Supp 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/29 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rigid:/j4Aqw5vgSsSSaa/drdjOz7mTLs false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q6IQ23 uniprotkb:Q8NDV7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16400536|imex:IM-25739-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 go:"GO:0005915"(zonula adherens) - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/29 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rigid:AoxlwqlSNrlHuG0OHWDCtJu7+jQ false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:O60716 uniprotkb:P11940 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16400541|imex:IM-25739-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N go:"GO:0005915"(zonula adherens) - - figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/09/01 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:RHv4Q12GfUcf6I/abEv+n0599tw false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q9UKV8 uniprotkb:Q8NDV7 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16400938|imex:IM-25739-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 go:"GO:0005915"(zonula adherens) - - figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rigid:yOxWDD/UCJ11wK9MKaI9r4DEn9Y false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q9UKV8 uniprotkb:O60716 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16400943|imex:IM-25739-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 go:"GO:0005915"(zonula adherens) - - figure legend:Supp. Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:XKJMvqsOZfusItJx8cIykupmuEg false O-phospho-L-serine:387-387 - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q6IQ23 uniprotkb:Q9UKV8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400551|imex:IM-25739-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N - - - figure legend:Fig. 1D, Supp Fig 1I, 1J, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rigid:4Rk108MhvTt/l6veTYRFtYc6XOw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IQ23 uniprotkb:O60716 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400551|imex:IM-25739-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 - - - figure legend:Fig. 1D, Supp Fig 1I, 1J, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:4Rk108MhvTt/l6veTYRFtYc6XOw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IQ23 uniprotkb:Q15633 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400551|imex:IM-25739-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N - - - figure legend:Fig. 1D, Supp Fig 1I, 1J, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 rigid:4Rk108MhvTt/l6veTYRFtYc6XOw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IQ23 uniprotkb:Q9UPY3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-395506|uniprotkb:O95943|uniprotkb:Q9UQ02|uniprotkb:A7E2D3|ensembl:ENSP00000343745|ensembl:ENSP00000376783|ensembl:ENSP00000435681|ensembl:ENSP00000437256|uniprotkb:E0AD28|uniprotkb:B3KRG4 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dicer_human(display_long)|uniprotkb:DICER1(gene name)|psi-mi:DICER1(display_short)|uniprotkb:DICER(gene name synonym)|uniprotkb:HERNA(gene name synonym)|uniprotkb:KIAA0928(gene name synonym)|uniprotkb:Helicase with RNase motif(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400551|imex:IM-25739-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_085124.2|refseq:NP_803187.1|refseq:NP_001182502.1|refseq:XP_011534901.1|refseq:XP_011534902.1|refseq:XP_011534903.1|refseq:XP_011534904.1|ensembl:ENSG00000100697(gene)|ensembl:ENST00000343455(transcript)|ensembl:ENST00000393063(transcript)|ensembl:ENST00000526495(transcript)|ensembl:ENST00000527414(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033167"(ARC complex)|go:"GO:0033168"(obsolete conversion of ds siRNA to ss siRNA involved in RNA interference)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0036404"(obsolete conversion of ds siRNA to ss siRNA)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|mint:Q9UPY3|rcsb pdb:2EB1|rcsb pdb:4NGB|rcsb pdb:4NGC|rcsb pdb:4NGD|rcsb pdb:4NGF|rcsb pdb:4NGG|rcsb pdb:4NH3|rcsb pdb:4NH5|rcsb pdb:4NH6|rcsb pdb:4NHA|rcsb pdb:4WYQ|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|reactome:R-HSA-203927|reactome:R-HSA-426486|go:"GO:0035280"(miRNA loading onto RISC)|reactome:R-HSA-9708296|refseq:NP_001258211.1|refseq:NP_001278557.1|refseq:XP_016876609.1|refseq:XP_016876610.1|dip:DIP-29664N - - - figure legend:Fig. 1D, Supp Fig 1I, 1J, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RhSXQEEvS9b0IOvnrPYhRd0MzI09606 rigid:4Rk108MhvTt/l6veTYRFtYc6XOw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IQ23 uniprotkb:Q8NDV7 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400551|imex:IM-25739-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 - - - figure legend:Fig. 1D, Supp Fig 1I, 1J, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rigid:4Rk108MhvTt/l6veTYRFtYc6XOw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IQ23 uniprotkb:P11940 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400551|imex:IM-25739-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Fig. 1D, Supp Fig 1I, 1J, 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:4Rk108MhvTt/l6veTYRFtYc6XOw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NDV7 uniprotkb:Q9UKV8 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400557|imex:IM-25739-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NDV7 uniprotkb:P11940 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400557|imex:IM-25739-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NDV7 uniprotkb:O60716 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400557|imex:IM-25739-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NDV7 uniprotkb:Q6IQ23 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400557|imex:IM-25739-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UKV8 uniprotkb:O60716 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400567|imex:IM-25739-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 - - - figure legend:Fig. 1D, Supp. Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UKV8 uniprotkb:Q6IQ23 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400567|imex:IM-25739-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 - - - figure legend:Fig. 1D, Supp. Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UKV8 uniprotkb:Q8NDV7 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400567|imex:IM-25739-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 - - - figure legend:Fig. 1D, Supp. Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UKV8 uniprotkb:P11940 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400567|imex:IM-25739-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Fig. 1D, Supp. Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IQ23 uniprotkb:Q9UKV8 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400693|imex:IM-25739-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N - - - figure legend:Supp Fig. 1J|comment:These interactions were shown to be RNA-independent by RNase treatment.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/29 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rigid:z+oPJ27SPzLcZIa/ICAOovICSNs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6IQ23 uniprotkb:Q9UPY3 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-395506|uniprotkb:O95943|uniprotkb:Q9UQ02|uniprotkb:A7E2D3|ensembl:ENSP00000343745|ensembl:ENSP00000376783|ensembl:ENSP00000435681|ensembl:ENSP00000437256|uniprotkb:E0AD28|uniprotkb:B3KRG4 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:dicer_human(display_long)|uniprotkb:DICER1(gene name)|psi-mi:DICER1(display_short)|uniprotkb:DICER(gene name synonym)|uniprotkb:HERNA(gene name synonym)|uniprotkb:KIAA0928(gene name synonym)|uniprotkb:Helicase with RNase motif(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400693|imex:IM-25739-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_085124.2|refseq:NP_803187.1|refseq:NP_001182502.1|refseq:XP_011534901.1|refseq:XP_011534902.1|refseq:XP_011534903.1|refseq:XP_011534904.1|ensembl:ENSG00000100697(gene)|ensembl:ENST00000343455(transcript)|ensembl:ENST00000393063(transcript)|ensembl:ENST00000526495(transcript)|ensembl:ENST00000527414(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033167"(ARC complex)|go:"GO:0033168"(obsolete conversion of ds siRNA to ss siRNA involved in RNA interference)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0036404"(obsolete conversion of ds siRNA to ss siRNA)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|mint:Q9UPY3|rcsb pdb:2EB1|rcsb pdb:4NGB|rcsb pdb:4NGC|rcsb pdb:4NGD|rcsb pdb:4NGF|rcsb pdb:4NGG|rcsb pdb:4NH3|rcsb pdb:4NH5|rcsb pdb:4NH6|rcsb pdb:4NHA|rcsb pdb:4WYQ|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|reactome:R-HSA-203927|reactome:R-HSA-426486|go:"GO:0035280"(miRNA loading onto RISC)|reactome:R-HSA-9708296|refseq:NP_001258211.1|refseq:NP_001278557.1|refseq:XP_016876609.1|refseq:XP_016876610.1|dip:DIP-29664N - - - figure legend:Supp Fig. 1J|comment:These interactions were shown to be RNA-independent by RNase treatment.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/29 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:RhSXQEEvS9b0IOvnrPYhRd0MzI09606 rigid:z+oPJ27SPzLcZIa/ICAOovICSNs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11940 uniprotkb:Q9UKV8 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400924|imex:IM-25739-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11940 uniprotkb:O60716 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400924|imex:IM-25739-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11940 uniprotkb:Q6IQ23 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400924|imex:IM-25739-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P11940 uniprotkb:Q8NDV7 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400924|imex:IM-25739-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 - - - figure legend:Fig. 1D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rigid:VZO7MwvfaVRU172hsnUHTnJfhNg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60716 uniprotkb:Q9UKV8 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400931|imex:IM-25739-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N - - - figure legend:Fig. 1D, Supp. Fig. 1I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rigid:EhFSIg6viQ3K4Up3NaGbWiHkado false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60716 uniprotkb:P11940 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400931|imex:IM-25739-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Fig. 1D, Supp. Fig. 1I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:EhFSIg6viQ3K4Up3NaGbWiHkado false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60716 uniprotkb:Q6IQ23 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400931|imex:IM-25739-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 - - - figure legend:Fig. 1D, Supp. Fig. 1I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rigid:EhFSIg6viQ3K4Up3NaGbWiHkado false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60716 uniprotkb:Q8NDV7 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 intact:EBI-2269715|uniprotkb:O15408|uniprotkb:Q658L5|uniprotkb:Q6NVB5|uniprotkb:Q8NEZ0|uniprotkb:Q8TBT8|uniprotkb:Q8TCR0|uniprotkb:Q9NV59|uniprotkb:Q9P268|uniprotkb:C9JAR8|ensembl:ENSP00000379144|ensembl:ENSP00000500873 psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:tnr6a_human(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short)|uniprotkb:CAGH26(gene name synonym)|uniprotkb:KIAA1460(gene name synonym)|uniprotkb:TNRC6(gene name synonym)|uniprotkb:CAG repeat protein 26(gene name synonym)|uniprotkb:Glycine-tryptophan protein of 182 kDa(gene name synonym)|uniprotkb:GW182 autoantigen(gene name synonym)|uniprotkb:EMSY interactor protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400931|imex:IM-25739-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 ensembl:ENST00000315183|ensembl:ENSP00000326900|ensembl:ENSP00000379144|ensembl:ENST00000672933|ensembl:ENSP00000500125|ensembl:ENSP00000500873|refseq:NP_055309.2|refseq:NP_001317449.1|refseq:XP_016878642.1|refseq:XP_005255314.1|dip:DIP-54489N|ensembl:ENSG00000090905(gene)|ensembl:ENSG00000288130(gene)|ensembl:ENST00000395799(transcript)|ensembl:ENST00000673084(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016442"(RISC complex)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR019486|interpro:IPR026805|interpro:IPR032226|interpro:IPR033501|interpro:IPR034924|interpro:IPR035979|mint:Q8NDV7|rcsb pdb:5W6V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8936459|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569 - - - figure legend:Fig. 1D, Supp. Fig. 1I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rogid:CovOl6RsNKv9t55lEGnLPo2gafY9606 rigid:EhFSIg6viQ3K4Up3NaGbWiHkado false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O60716 uniprotkb:Q15633 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33 psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400931|imex:IM-25739-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N - - - figure legend:Fig. 1D, Supp. Fig. 1I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606 rigid:EhFSIg6viQ3K4Up3NaGbWiHkado false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UKV8 uniprotkb:Q6IQ23 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16401003|imex:IM-25739-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0044291"(cell-cell contact zone) - - figure legend:Supp Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rigid:/j4Aqw5vgSsSSaa/drdjOz7mTLs false O-phospho-L-serine:387-387 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:F1PQZ7 uniprotkb:F1PE20 intact:EBI-16400718|ensembl:ENSCAFP00000001710 intact:EBI-16400699|ensembl:ENSCAFP00000012717 psi-mi:f1pqz7_canlf(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short) psi-mi:f1pe20_canlf(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16400775|imex:IM-25739-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000001196(gene)|ensembl:ENSCAFT00000001857(transcript)|go:"GO:0006417"(regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397 interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|interpro:IPR001849(Pleckstrin-like)|ensembl:ENSCAFG00000008664(gene)|ensembl:ENSCAFT00000013753(transcript)|go:"GO:0005915"(zonula adherens)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP) - - - figure legend:Supp. Fig. 1F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2017/06/01 2020/01/08 rogid:q0KaPGf3BxHNRkhvYRe3PlB2l789615 rogid:kKVdddrXFE5aap1zZDMJ9cX4C+E9615 rigid:LbDNx7Ny1ygyqNnvCVPYGx3VOLk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UKV8 uniprotkb:Q6IQ23 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:0813"(proximity ligation assay) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-16400956|imex:IM-25739-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 go:"GO:0044291"(cell-cell contact zone) - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rigid:/j4Aqw5vgSsSSaa/drdjOz7mTLs false O-phospho-L-serine:387-387 myc tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q6IQ23 uniprotkb:O60716 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0813"(proximity ligation assay) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-16400965|imex:IM-25739-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 go:"GO:0044291"(cell-cell contact zone) - - figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2017/06/01 2017/08/30 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:Qyu1PyRRTC7sacO9I1Vsia+58l0 false myc tag:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:E2R434 uniprotkb:F1PQZ7 intact:EBI-3647522|ensembl:ENSCAFP00000011503 intact:EBI-16400718|ensembl:ENSCAFP00000001710 psi-mi:e2r434_canlf(display_long)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short) psi-mi:f1pqz7_canlf(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short) psi-mi:"MI:0663"(confocal microscopy) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16400978|imex:IM-25739-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005631252.1|refseq:XP_013976615.1|ensembl:ENSCAFG00000007767(gene)|ensembl:ENSCAFT00000012414(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016342"(catenin complex)|go:"GO:0030496"(midbody)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|reactome:R-CFA-5218920|reactome:R-CFA-418990 ensembl:ENSCAFG00000001196(gene)|ensembl:ENSCAFT00000001857(transcript)|go:"GO:0006417"(regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397 go:"GO:0005915"(zonula adherens) - - figure legend:Supp Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2017/06/01 2020/01/08 rogid:rxbySEk56GEJEngCd5YEE94OMtU9615 rogid:q0KaPGf3BxHNRkhvYRe3PlB2l789615 rigid:u4L8ShoRlvIHtYTlDs389RRLtaI false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:E2R434 uniprotkb:F1PMK2 intact:EBI-3647522|ensembl:ENSCAFP00000011503 intact:EBI-16400991|ensembl:ENSCAFP00000025858 psi-mi:e2r434_canlf(display_long)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short) psi-mi:f1pmk2_canlf(display_long)|uniprotkb:TNRC6A(gene name)|psi-mi:TNRC6A(display_short) psi-mi:"MI:0663"(confocal microscopy) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16400987|imex:IM-25739-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005631252.1|refseq:XP_013976615.1|ensembl:ENSCAFG00000007767(gene)|ensembl:ENSCAFT00000012414(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016342"(catenin complex)|go:"GO:0030496"(midbody)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|reactome:R-CFA-5218920|reactome:R-CFA-418990 ensembl:ENSCAFG00000017531(gene)|ensembl:ENSCAFT00000027808(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR019486|interpro:IPR032226|interpro:IPR033501 go:"GO:0005915"(zonula adherens) - - figure legend:Supp Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2017/06/01 2020/01/08 rogid:rxbySEk56GEJEngCd5YEE94OMtU9615 rogid:kaBZpUzQGJRr+STuPesUwX+VJ8o9615 rigid:xNDiMmpuyV+qFYZnk32FOVVUMnM false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:E2R434 uniprotkb:J9P326 intact:EBI-3647522|ensembl:ENSCAFP00000011503 intact:EBI-16401000|ensembl:ENSCAFP00000039955 psi-mi:e2r434_canlf(display_long)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short) psi-mi:j9p326_canlf(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short) psi-mi:"MI:0663"(confocal microscopy) Kourtidis, et al. (2017) imex:IM-25739|pubmed:28877994 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-16400996|imex:IM-25739-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005631252.1|refseq:XP_013976615.1|ensembl:ENSCAFG00000007767(gene)|ensembl:ENSCAFT00000012414(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016342"(catenin complex)|go:"GO:0030496"(midbody)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|reactome:R-CFA-5218920|reactome:R-CFA-418990 ensembl:ENSCAFG00000000567(gene)|ensembl:ENSCAFT00000042991(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|reactome:R-CFA-156827|reactome:R-CFA-429947|reactome:R-CFA-450408|reactome:R-CFA-72649|reactome:R-CFA-975956|reactome:R-CFA-975957 go:"GO:0005915"(zonula adherens) - - figure legend:Supp. Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2017/06/01 2020/01/08 rogid:rxbySEk56GEJEngCd5YEE94OMtU9615 rogid:UAGxDy3A2wW03NHsi3Q7mrCr8qs9615 rigid:tojiiGJH2VUKYqy4BDskMRC7f4g false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)