#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5VY80 uniprotkb:P26718 intact:EBI-16364752|ensembl:ENSP00000286380|ensembl:ENSP00000356310|uniprotkb:A3KME4|uniprotkb:Q8TE74 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 psi-mi:ulbp6_human(display_long)|uniprotkb:Retinoic acid early transcript 1L protein(gene name synonym)|uniprotkb:ULBP6(gene name synonym)|uniprotkb:RAET1L(gene name)|psi-mi:RAET1L(display_short) psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16364749|imex:IM-26180-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000155918(gene)|ensembl:ENST00000286380(transcript)|ensembl:ENST00000367341(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|rcsb pdb:4S0U|reactome:R-HSA-163125|refseq:NP_570970.2|refseq:XP_011533788.1 reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N - - - figure legend:2A, 4G, table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:15.5x10^-9(molar) 2017/06/20 2017/08/23 rogid:qmBpBwkDVEzA6OoRr0bXyIdVzzw9606 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rigid:apqtvGJb8v24nGblCdD9KiSsCYk false biotin tag:?-?|his tag:?-?|sufficient binding region:29-207|variant:147-147,106-106|mutation:147-147|mutation decreasing interaction strength:106-106 sufficient binding region:80-216 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5VY80 uniprotkb:P26718 intact:EBI-16364752|ensembl:ENSP00000286380|ensembl:ENSP00000356310|uniprotkb:A3KME4|uniprotkb:Q8TE74 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 psi-mi:ulbp6_human(display_long)|uniprotkb:Retinoic acid early transcript 1L protein(gene name synonym)|uniprotkb:ULBP6(gene name synonym)|uniprotkb:RAET1L(gene name)|psi-mi:RAET1L(display_short) psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16364912|imex:IM-26180-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000155918(gene)|ensembl:ENST00000286380(transcript)|ensembl:ENST00000367341(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|rcsb pdb:4S0U|reactome:R-HSA-163125|refseq:NP_570970.2|refseq:XP_011533788.1 reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N - - - figure legend:2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:13.0x10^-9(molar) 2017/06/20 2017/08/23 rogid:qmBpBwkDVEzA6OoRr0bXyIdVzzw9606 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rigid:apqtvGJb8v24nGblCdD9KiSsCYk false sufficient binding region:29-207|variant:147-147,106-106 sufficient binding region:80-216|his tag:?-?|biotin tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BZM6 uniprotkb:P26718 intact:EBI-16365037|ensembl:ENSP00000229708|uniprotkb:Q5VY81|uniprotkb:Q8IZW3|uniprotkb:Q8IZX6 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 psi-mi:ulbp1_human(display_long)|uniprotkb:ALCAN-beta(gene name synonym)|uniprotkb:Retinoic acid early transcript 1I(gene name synonym)|uniprotkb:NKG2D ligand 1(gene name synonym)|uniprotkb:ULBP1(gene name)|psi-mi:ULBP1(display_short)|uniprotkb:N2DL1(gene name synonym)|uniprotkb:RAET1I(gene name synonym) psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16365018|imex:IM-26180-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111981(gene)|ensembl:ENST00000229708(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|reactome:R-HSA-198933|refseq:NP_001304018.1|refseq:NP_079494.1 reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N - - - figure legend:2A-2, Supp fig 2A|comment:Kd values from Supp. Table 1 and Supp. figure 2A have both been entered.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:307.0x10^-9(molar)|kd:294.0x10^-9(molar) 2017/06/20 2017/08/23 rogid:PSK5rSDPPq0s+n3JRmMptk0SaeI9606 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rigid:LsqE+KtrlHk8ZsDlkpk+myjK8uQ false biotin tag:?-?|his tag:?-?|sufficient binding region:29-206..207 sufficient binding region:80-216 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BZM6 uniprotkb:P26718 intact:EBI-16365037|ensembl:ENSP00000229708|uniprotkb:Q5VY81|uniprotkb:Q8IZW3|uniprotkb:Q8IZX6 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 psi-mi:ulbp1_human(display_long)|uniprotkb:ALCAN-beta(gene name synonym)|uniprotkb:Retinoic acid early transcript 1I(gene name synonym)|uniprotkb:NKG2D ligand 1(gene name synonym)|uniprotkb:ULBP1(gene name)|psi-mi:ULBP1(display_short)|uniprotkb:N2DL1(gene name synonym)|uniprotkb:RAET1I(gene name synonym) psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16365147|imex:IM-26180-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111981(gene)|ensembl:ENST00000229708(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|reactome:R-HSA-198933|refseq:NP_001304018.1|refseq:NP_079494.1 reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N - - - figure legend:2B-2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.46x10^-7(molar) 2017/06/20 2017/08/23 rogid:PSK5rSDPPq0s+n3JRmMptk0SaeI9606 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rigid:LsqE+KtrlHk8ZsDlkpk+myjK8uQ false sufficient binding region:29-206..207 his tag:?-?|biotin tag:?-?|sufficient binding region:80-216 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BZM5 uniprotkb:P26718 intact:EBI-3919993|ensembl:ENSP00000356320|uniprotkb:Q5VUN4 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 psi-mi:ulbp2_human(display_long)|uniprotkb:ULBP2(gene name)|psi-mi:ULBP2(display_short)|uniprotkb:NKG2D ligand 2(gene name synonym)|uniprotkb:N2DL2(gene name synonym)|uniprotkb:RAET1H(gene name synonym)|uniprotkb:ALCAN-alpha(gene name synonym)|uniprotkb:Retinoic acid early transcript 1H(gene name synonym)|uniprotkb:UNQ463/PRO791(orf name) psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16365437|imex:IM-26180-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131015(gene)|ensembl:ENST00000367351(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|reactome:R-HSA-163125|refseq:NP_079493.1 reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N - - - figure legend:Supp fig 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:38.5x10^-6(molar) 2017/06/20 2017/08/23 rogid:zuq4AAgsMCKpAdAWhIZxEcpcv4Q9606 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rigid:qiGQVKKlU1M60tQrOfSLZODu5ng false sufficient binding region:29-206 his tag:?-?|biotin tag:?-?|sufficient binding region:80-216 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BZM4 uniprotkb:P26718 intact:EBI-1032551|uniprotkb:Q8IZX5|uniprotkb:Q8TE75|uniprotkb:Q5VY82|ensembl:ENSP00000356308|ensembl:ENSP00000403562 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 psi-mi:ulbp3_human(display_long)|uniprotkb:NKG2D ligand 3(gene name synonym)|uniprotkb:ULBP3(gene name)|psi-mi:ULBP3(display_short)|uniprotkb:N2DL3(gene name synonym)|uniprotkb:RAET1N(gene name synonym)|uniprotkb:ALCAN-gamma(gene name synonym)|uniprotkb:Retinoic acid early transcript 1N(gene name synonym) psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16365519|imex:IM-26180-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078794.1|ensembl:ENSG00000131019(gene)|ensembl:ENST00000367339(transcript)|ensembl:ENST00000438272(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|rcsb pdb:1KCG|reactome:R-HSA-198933 reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N - - - figure legend:Supp fig 2C, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:657.9x10^-9(molar) 2017/06/20 2017/08/23 rogid:5myzHeEnjNcdi5NtcpGuqI9c7gA9606 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rigid:95fLM7Q4hhqTK8Wc1Pj4vUXP29o false his tag:?-?|biotin tag:?-?|sufficient binding region:30-207 sufficient binding region:80-216 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26718 uniprotkb:Q8TD07 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 intact:EBI-16365677|ensembl:ENSP00000349709|uniprotkb:A6YF59|uniprotkb:Q5VYB7|uniprotkb:Q5VYB8|uniprotkb:Q8TEZ2|uniprotkb:Q96L41|intact:EBI-16417333|intact:EBI-16417358 psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:rae1e_human(display_long)|uniprotkb:NKG2D ligand 4(gene name synonym)|uniprotkb:Lymphocyte effector toxicity activation ligand(gene name synonym)|uniprotkb:RAE-1-like transcript 4(gene name synonym)|uniprotkb:UL16-binding protein 4(gene name synonym)|uniprotkb:RAET1E(gene name)|psi-mi:RAET1E(display_short)|uniprotkb:LETAL(gene name synonym)|uniprotkb:N2DL4(gene name synonym)|uniprotkb:ULBP4(gene name synonym)|uniprotkb:UNQ1867/PRO4303(orf name) psi-mi:"MI:0107"(surface plasmon resonance) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16365663|imex:IM-26180-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N ensembl:ENSG00000164520(gene)|ensembl:ENST00000357183(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|reactome:R-HSA-198933|refseq:NP_001230254.1|refseq:NP_001230256.1|refseq:NP_001230257.1|refseq:NP_631904.1|refseq:XP_011533781.1 - - - figure legend:Supp fig 2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:3.15x10^-6(molar) 2017/06/20 2017/08/23 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rogid:ED1vlb7qfcUNlxg90bEKKbME8TA9606 rigid:kGXIKFHd7xLL7QjTQ6QL1mX29wQ false his tag:?-?|biotin tag:?-?|sufficient binding region:80-216 sufficient binding region:31-205 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BZM5 uniprotkb:P26718 intact:EBI-3919993|ensembl:ENSP00000356320|uniprotkb:Q5VUN4 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 psi-mi:ulbp2_human(display_long)|uniprotkb:ULBP2(gene name)|psi-mi:ULBP2(display_short)|uniprotkb:NKG2D ligand 2(gene name synonym)|uniprotkb:N2DL2(gene name synonym)|uniprotkb:RAET1H(gene name synonym)|uniprotkb:ALCAN-alpha(gene name synonym)|uniprotkb:Retinoic acid early transcript 1H(gene name synonym)|uniprotkb:UNQ463/PRO791(orf name) psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16368137|imex:IM-26180-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131015(gene)|ensembl:ENST00000367351(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|reactome:R-HSA-163125|refseq:NP_079493.1 reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:34.8x10^-6(molar) 2017/06/20 2017/08/23 rogid:zuq4AAgsMCKpAdAWhIZxEcpcv4Q9606 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rigid:qiGQVKKlU1M60tQrOfSLZODu5ng false sufficient binding region:29-206 his tag:?-?|biotin tag:?-?|sufficient binding region:80-216 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26718 uniprotkb:Q8TD07 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 intact:EBI-16365677|ensembl:ENSP00000349709|uniprotkb:A6YF59|uniprotkb:Q5VYB7|uniprotkb:Q5VYB8|uniprotkb:Q8TEZ2|uniprotkb:Q96L41|intact:EBI-16417333|intact:EBI-16417358 psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:rae1e_human(display_long)|uniprotkb:NKG2D ligand 4(gene name synonym)|uniprotkb:Lymphocyte effector toxicity activation ligand(gene name synonym)|uniprotkb:RAE-1-like transcript 4(gene name synonym)|uniprotkb:UL16-binding protein 4(gene name synonym)|uniprotkb:RAET1E(gene name)|psi-mi:RAET1E(display_short)|uniprotkb:LETAL(gene name synonym)|uniprotkb:N2DL4(gene name synonym)|uniprotkb:ULBP4(gene name synonym)|uniprotkb:UNQ1867/PRO4303(orf name) psi-mi:"MI:0107"(surface plasmon resonance) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16368150|imex:IM-26180-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N ensembl:ENSG00000164520(gene)|ensembl:ENST00000357183(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046703"(natural killer cell lectin-like receptor binding)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|reactome:R-HSA-198933|refseq:NP_001230254.1|refseq:NP_001230256.1|refseq:NP_001230257.1|refseq:NP_631904.1|refseq:XP_011533781.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:2.1x10^-6(molar) 2017/06/20 2017/08/23 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rogid:ED1vlb7qfcUNlxg90bEKKbME8TA9606 rigid:kGXIKFHd7xLL7QjTQ6QL1mX29wQ false his tag:?-?|biotin tag:?-?|sufficient binding region:80-216 sufficient binding region:31-205 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q5VY80 uniprotkb:P26718 intact:EBI-16364752|ensembl:ENSP00000286380|ensembl:ENSP00000356310|uniprotkb:A3KME4|uniprotkb:Q8TE74 intact:EBI-458344|ensembl:ENSP00000240618|ensembl:ENSP00000446003|uniprotkb:Q9NR41|uniprotkb:A8K7K5|uniprotkb:A8K7P4 psi-mi:ulbp6_human(display_long)|uniprotkb:Retinoic acid early transcript 1L protein(gene name synonym)|uniprotkb:ULBP6(gene name synonym)|uniprotkb:RAET1L(gene name)|psi-mi:RAET1L(display_short) psi-mi:nkg2d_human(display_long)|uniprotkb:KLRK1(gene name)|psi-mi:KLRK1(display_short)|uniprotkb:NKG2D(gene name synonym)|uniprotkb:NKG2-D-activating NK receptor(gene name synonym)|uniprotkb:NK cell receptor D(gene name synonym)|uniprotkb:Killer cell lectin-like receptor subfamily K member 1(gene name synonym)|uniprotkb:D12S2489E(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zuo et al. (2017) pubmed:28559451|imex:IM-26180 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16367924|wwpdb:4s0u|imex:IM-26180-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000155918(gene)|ensembl:ENST00000286380(transcript)|ensembl:ENST00000367341(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR037055|rcsb pdb:4S0U|reactome:R-HSA-163125|refseq:NP_570970.2|refseq:XP_011533788.1 reactome:R-HSA-2424491|reactome:R-HSA-2172127|ensembl:ENSG00000213809(gene)|ensembl:ENST00000540818(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:2000502"(negative regulation of natural killer cell chemotaxis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR033992|interpro:IPR042169|rcsb pdb:1HYR|rcsb pdb:1KCG|rcsb pdb:1MPU|rcsb pdb:4PDC|rcsb pdb:4S0U|ensembl:ENST00000240618(transcript)|reactome:R-HSA-198933|refseq:NP_001186734.1|refseq:NP_031386.2|dip:DIP-31100N - - - figure legend:Supp Table 2|3d-resolution:2.35A|3d-r-factors:RFree =0.286 RWork=0.238|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/20 2017/08/23 rogid:qmBpBwkDVEzA6OoRr0bXyIdVzzw9606 rogid:KAqdqIVvc4LUwx7y0KRMc87FsUM9606 rigid:apqtvGJb8v24nGblCdD9KiSsCYk false sufficient binding region:29-207|mutation:34-34 sufficient binding region:80-216 1 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)