#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A0A583ZBW8 uniprotkb:Q14954 intact:EBI-9978392|uniprotkb:P30502 intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711|ensembl:ENSP00000481628|ensembl:ENSP00000482060|ensembl:ENSP00000482170|ensembl:ENSP00000482900|ensembl:ENSP00000483434|ensembl:ENSP00000491232|ensembl:ENSP00000492239|ensembl:ENSP00000492347|ensembl:ENSP00000494266|ensembl:ENSP00000494623|ensembl:ENSP00000495438 psi-mi:1c02_human(display_long)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)|uniprotkb:HLAC(gene name synonym)|uniprotkb:MHC class I antigen Cw*2(gene name synonym) psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16370810|imex:IM-26182-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0055038"(recycling endosome membrane)|uniprotkb:P10321(see-also)|go:"GO:0009986"(cell surface)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0046977"(TAP binding)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0006955"(immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|ensembl:ENST00000420206|ensembl:ENSP00000410214|ensembl:ENSG00000228299|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|interpro:IPR036179|interpro:IPR037055|uniprotkb:A0A0B7NNJ6(see-also) refseq:NP_055327.1|ensembl:ENSG00000273517(gene)|ensembl:ENSG00000273603(gene)|ensembl:ENSG00000275421(gene)|ensembl:ENSG00000276327(gene)|ensembl:ENSG00000278120(gene)|ensembl:ENSG00000278304(gene)|ensembl:ENSG00000284120(gene)|ensembl:ENSG00000284150(gene)|ensembl:ENSG00000284560(gene)|ensembl:ENST00000611996(transcript)|ensembl:ENST00000612447(transcript)|ensembl:ENST00000617661(transcript)|ensembl:ENST00000618071(transcript)|ensembl:ENST00000621207(transcript)|ensembl:ENST00000622039(transcript)|ensembl:ENST00000638832(transcript)|ensembl:ENST00000639093(transcript)|ensembl:ENST00000639232(transcript)|ensembl:ENST00000643062(transcript)|ensembl:ENST00000644318(transcript)|ensembl:ENST00000645834(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 - no-uniprot-update:|caution:"The protein could not be merged with EBI-1051396 because of some conflicts with the protein sequence (features which cannot be shifted)." - figure legend:Fig 1A and text|comment:C0202 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2018/04/06 rogid:to6Sq6pB+Vn5nSM0v5vkRoYCpqk9606 rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606 rigid:w+28xeE1Kqy1FZQFJDFvCninYaQ false variant:5-5|variant:10-10|variant:73-74|variant:92-92|variant:179-179|variant:202-202|variant:364-364 sufficient binding region:22..22-245..245|fc-igg tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P10321 uniprotkb:Q14954 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711|ensembl:ENSP00000481628|ensembl:ENSP00000482060|ensembl:ENSP00000482170|ensembl:ENSP00000482900|ensembl:ENSP00000483434|ensembl:ENSP00000491232|ensembl:ENSP00000492239|ensembl:ENSP00000492347|ensembl:ENSP00000494266|ensembl:ENSP00000494623|ensembl:ENSP00000495438 psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16370855|imex:IM-26182-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 refseq:NP_055327.1|ensembl:ENSG00000273517(gene)|ensembl:ENSG00000273603(gene)|ensembl:ENSG00000275421(gene)|ensembl:ENSG00000276327(gene)|ensembl:ENSG00000278120(gene)|ensembl:ENSG00000278304(gene)|ensembl:ENSG00000284120(gene)|ensembl:ENSG00000284150(gene)|ensembl:ENSG00000284560(gene)|ensembl:ENST00000611996(transcript)|ensembl:ENST00000612447(transcript)|ensembl:ENST00000617661(transcript)|ensembl:ENST00000618071(transcript)|ensembl:ENST00000621207(transcript)|ensembl:ENST00000622039(transcript)|ensembl:ENST00000638832(transcript)|ensembl:ENST00000639093(transcript)|ensembl:ENST00000639232(transcript)|ensembl:ENST00000643062(transcript)|ensembl:ENST00000644318(transcript)|ensembl:ENST00000645834(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 - - - figure legend:Fig 1A-2 and text|comment:C0401 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606 rigid:bNBmZjOL62AsbYtJa9/LgD42p0Q false - sufficient binding region:22..22-245..245|fc-igg tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P10321 uniprotkb:Q14954 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711|ensembl:ENSP00000481628|ensembl:ENSP00000482060|ensembl:ENSP00000482170|ensembl:ENSP00000482900|ensembl:ENSP00000483434|ensembl:ENSP00000491232|ensembl:ENSP00000492239|ensembl:ENSP00000492347|ensembl:ENSP00000494266|ensembl:ENSP00000494623|ensembl:ENSP00000495438 psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16370890|imex:IM-26182-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 refseq:NP_055327.1|ensembl:ENSG00000273517(gene)|ensembl:ENSG00000273603(gene)|ensembl:ENSG00000275421(gene)|ensembl:ENSG00000276327(gene)|ensembl:ENSG00000278120(gene)|ensembl:ENSG00000278304(gene)|ensembl:ENSG00000284120(gene)|ensembl:ENSG00000284150(gene)|ensembl:ENSG00000284560(gene)|ensembl:ENST00000611996(transcript)|ensembl:ENST00000612447(transcript)|ensembl:ENST00000617661(transcript)|ensembl:ENST00000618071(transcript)|ensembl:ENST00000621207(transcript)|ensembl:ENST00000622039(transcript)|ensembl:ENST00000638832(transcript)|ensembl:ENST00000639093(transcript)|ensembl:ENST00000639232(transcript)|ensembl:ENST00000643062(transcript)|ensembl:ENST00000644318(transcript)|ensembl:ENST00000645834(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 - - - figure legend:Fig 1A-3 and text|comment:C0501 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606 rigid:bNBmZjOL62AsbYtJa9/LgD42p0Q false - sufficient binding region:22..22-245..245|fc-igg tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P10321 uniprotkb:Q14954 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711|ensembl:ENSP00000481628|ensembl:ENSP00000482060|ensembl:ENSP00000482170|ensembl:ENSP00000482900|ensembl:ENSP00000483434|ensembl:ENSP00000491232|ensembl:ENSP00000492239|ensembl:ENSP00000492347|ensembl:ENSP00000494266|ensembl:ENSP00000494623|ensembl:ENSP00000495438 psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16370901|imex:IM-26182-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 refseq:NP_055327.1|ensembl:ENSG00000273517(gene)|ensembl:ENSG00000273603(gene)|ensembl:ENSG00000275421(gene)|ensembl:ENSG00000276327(gene)|ensembl:ENSG00000278120(gene)|ensembl:ENSG00000278304(gene)|ensembl:ENSG00000284120(gene)|ensembl:ENSG00000284150(gene)|ensembl:ENSG00000284560(gene)|ensembl:ENST00000611996(transcript)|ensembl:ENST00000612447(transcript)|ensembl:ENST00000617661(transcript)|ensembl:ENST00000618071(transcript)|ensembl:ENST00000621207(transcript)|ensembl:ENST00000622039(transcript)|ensembl:ENST00000638832(transcript)|ensembl:ENST00000639093(transcript)|ensembl:ENST00000639232(transcript)|ensembl:ENST00000643062(transcript)|ensembl:ENST00000644318(transcript)|ensembl:ENST00000645834(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 - - - figure legend:Fig 1A-4 and text|comment:C0602 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606 rigid:bNBmZjOL62AsbYtJa9/LgD42p0Q false - sufficient binding region:22..22-245..245|fc-igg tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P10321 uniprotkb:Q14954 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711|ensembl:ENSP00000481628|ensembl:ENSP00000482060|ensembl:ENSP00000482170|ensembl:ENSP00000482900|ensembl:ENSP00000483434|ensembl:ENSP00000491232|ensembl:ENSP00000492239|ensembl:ENSP00000492347|ensembl:ENSP00000494266|ensembl:ENSP00000494623|ensembl:ENSP00000495438 psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16370910|imex:IM-26182-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 refseq:NP_055327.1|ensembl:ENSG00000273517(gene)|ensembl:ENSG00000273603(gene)|ensembl:ENSG00000275421(gene)|ensembl:ENSG00000276327(gene)|ensembl:ENSG00000278120(gene)|ensembl:ENSG00000278304(gene)|ensembl:ENSG00000284120(gene)|ensembl:ENSG00000284150(gene)|ensembl:ENSG00000284560(gene)|ensembl:ENST00000611996(transcript)|ensembl:ENST00000612447(transcript)|ensembl:ENST00000617661(transcript)|ensembl:ENST00000618071(transcript)|ensembl:ENST00000621207(transcript)|ensembl:ENST00000622039(transcript)|ensembl:ENST00000638832(transcript)|ensembl:ENST00000639093(transcript)|ensembl:ENST00000639232(transcript)|ensembl:ENST00000643062(transcript)|ensembl:ENST00000644318(transcript)|ensembl:ENST00000645834(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 - - - figure legend:Fig 1A-5 and text|comment:C1502 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606 rigid:bNBmZjOL62AsbYtJa9/LgD42p0Q false - sufficient binding region:22..22-245..245|fc-igg tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P10321 uniprotkb:Q14954 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711|ensembl:ENSP00000481628|ensembl:ENSP00000482060|ensembl:ENSP00000482170|ensembl:ENSP00000482900|ensembl:ENSP00000483434|ensembl:ENSP00000491232|ensembl:ENSP00000492239|ensembl:ENSP00000492347|ensembl:ENSP00000494266|ensembl:ENSP00000494623|ensembl:ENSP00000495438 psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16370959|imex:IM-26182-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 refseq:NP_055327.1|ensembl:ENSG00000273517(gene)|ensembl:ENSG00000273603(gene)|ensembl:ENSG00000275421(gene)|ensembl:ENSG00000276327(gene)|ensembl:ENSG00000278120(gene)|ensembl:ENSG00000278304(gene)|ensembl:ENSG00000284120(gene)|ensembl:ENSG00000284150(gene)|ensembl:ENSG00000284560(gene)|ensembl:ENST00000611996(transcript)|ensembl:ENST00000612447(transcript)|ensembl:ENST00000617661(transcript)|ensembl:ENST00000618071(transcript)|ensembl:ENST00000621207(transcript)|ensembl:ENST00000622039(transcript)|ensembl:ENST00000638832(transcript)|ensembl:ENST00000639093(transcript)|ensembl:ENST00000639232(transcript)|ensembl:ENST00000643062(transcript)|ensembl:ENST00000644318(transcript)|ensembl:ENST00000645834(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 - - - figure legend:Fig 1A-6 and text|comment:C1701 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606 rigid:bNBmZjOL62AsbYtJa9/LgD42p0Q false - sufficient binding region:22..22-245..245|fc-igg tag:c-c - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q14954 uniprotkb:P10321 intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711|ensembl:ENSP00000481628|ensembl:ENSP00000482060|ensembl:ENSP00000482170|ensembl:ENSP00000482900|ensembl:ENSP00000483434|ensembl:ENSP00000491232|ensembl:ENSP00000492239|ensembl:ENSP00000492347|ensembl:ENSP00000494266|ensembl:ENSP00000494623|ensembl:ENSP00000495438 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym) psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16371057|imex:IM-26182-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055327.1|ensembl:ENSG00000273517(gene)|ensembl:ENSG00000273603(gene)|ensembl:ENSG00000275421(gene)|ensembl:ENSG00000276327(gene)|ensembl:ENSG00000278120(gene)|ensembl:ENSG00000278304(gene)|ensembl:ENSG00000284120(gene)|ensembl:ENSG00000284150(gene)|ensembl:ENSG00000284560(gene)|ensembl:ENST00000611996(transcript)|ensembl:ENST00000612447(transcript)|ensembl:ENST00000617661(transcript)|ensembl:ENST00000618071(transcript)|ensembl:ENST00000621207(transcript)|ensembl:ENST00000622039(transcript)|ensembl:ENST00000638832(transcript)|ensembl:ENST00000639093(transcript)|ensembl:ENST00000639232(transcript)|ensembl:ENST00000643062(transcript)|ensembl:ENST00000644318(transcript)|ensembl:ENST00000645834(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 - - - figure legend:Fig 1A-7 and text|comment:C1802 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rigid:bNBmZjOL62AsbYtJa9/LgD42p0Q false sufficient binding region:22..22-245..245|fc-igg tag:c-c variant:319-319 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P43626 uniprotkb:A0A583ZBW7 intact:EBI-8684277|uniprotkb:Q6IST4|intact:MINT-8013645|uniprotkb:Q32WE6|uniprotkb:O43470|ensembl:ENSP00000478232|ensembl:ENSP00000478263|ensembl:ENSP00000479363|ensembl:ENSP00000482120|ensembl:ENSP00000484361|ensembl:ENSP00000484559|ensembl:ENSP00000291633 intact:EBI-13916865|uniprotkb:O02865|uniprotkb:O19676|uniprotkb:P30500|uniprotkb:Q29986|uniprotkb:Q9UQS9 psi-mi:ki2l1_human(display_long)|uniprotkb:KIR2DL1(gene name)|psi-mi:KIR2DL1(display_short)|uniprotkb:CD158 antigen-like family member A(gene name synonym)|uniprotkb:CD158A(gene name synonym)|uniprotkb:NKAT1(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 1(gene name synonym)|uniprotkb:p58 natural killer cell receptor clones CL-42/47.11(gene name synonym)|uniprotkb:p58.1 MHC class-I-specific NK receptor(gene name synonym) psi-mi:1c01_human(display_long)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)|uniprotkb:HLAC(gene name synonym)|uniprotkb:MHC class I antigen Cw*1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16371233|imex:IM-26182-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055033.2|ensembl:ENSG00000125498(gene)|ensembl:ENSG00000273794(gene)|ensembl:ENSG00000276625(gene)|ensembl:ENSG00000277833(gene)|ensembl:ENSG00000278495(gene)|ensembl:ENSG00000278738(gene)|ensembl:ENSG00000278821(gene)|ensembl:ENST00000291633(transcript)|ensembl:ENST00000611611(transcript)|ensembl:ENST00000615920(transcript)|ensembl:ENST00000617376(transcript)|ensembl:ENST00000618563(transcript)|ensembl:ENST00000620449(transcript)|ensembl:ENST00000622463(transcript)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IM9|rcsb pdb:1NKR|reactome:R-HSA-198933 go:"GO:0055038"(recycling endosome membrane)|uniprotkb:P10321(see-also)|ensembl:ENST00000438171|ensembl:ENSP00000393374|ensembl:ENSG00000237022|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0009986"(cell surface)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0046977"(TAP binding)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0006955"(immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR036179|interpro:IPR037055 - comment:mint no-uniprot-update:|caution:"The protein could not be merged with EBI-1051396 because of some conflicts with the protein sequence (features which cannot be shifted)." figure legend:Fig 1Ai and text|comment:C0102 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2017/08/23 rogid:8lycFqdUAUK1Ww2NpLHNFtFPlZ49606 rogid:yZNtsKoOb6HhKK3W3XprXxlPin09606 rigid:nIu0AxjnPyna63vKIcWSMieztcE false sufficient binding region:22-242|fc-igg tag:c-c variant:5-5|variant:92-92|variant:179-179|variant:202-202|variant:364-364 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P43626 uniprotkb:Q53YP1 intact:EBI-8684277|uniprotkb:Q6IST4|intact:MINT-8013645|uniprotkb:Q32WE6|uniprotkb:O43470|ensembl:ENSP00000478232|ensembl:ENSP00000478263|ensembl:ENSP00000479363|ensembl:ENSP00000482120|ensembl:ENSP00000484361|ensembl:ENSP00000484559|ensembl:ENSP00000291633 intact:EBI-13917186|uniprotkb:O62883|uniprotkb:O78060|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:P30503|uniprotkb:Q29743|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q9GIK8|uniprotkb:Q9TQB4 psi-mi:ki2l1_human(display_long)|uniprotkb:KIR2DL1(gene name)|psi-mi:KIR2DL1(display_short)|uniprotkb:CD158 antigen-like family member A(gene name synonym)|uniprotkb:CD158A(gene name synonym)|uniprotkb:NKAT1(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 1(gene name synonym)|uniprotkb:p58 natural killer cell receptor clones CL-42/47.11(gene name synonym)|uniprotkb:p58.1 MHC class-I-specific NK receptor(gene name synonym) psi-mi:1c03_human(display_long)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short)|uniprotkb:HLAC(gene name synonym)|uniprotkb:MHC class I antigen Cw*3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16372106|imex:IM-26182-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055033.2|ensembl:ENSG00000125498(gene)|ensembl:ENSG00000273794(gene)|ensembl:ENSG00000276625(gene)|ensembl:ENSG00000277833(gene)|ensembl:ENSG00000278495(gene)|ensembl:ENSG00000278738(gene)|ensembl:ENSG00000278821(gene)|ensembl:ENST00000291633(transcript)|ensembl:ENST00000611611(transcript)|ensembl:ENST00000615920(transcript)|ensembl:ENST00000617376(transcript)|ensembl:ENST00000618563(transcript)|ensembl:ENST00000620449(transcript)|ensembl:ENST00000622463(transcript)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IM9|rcsb pdb:1NKR|reactome:R-HSA-198933 go:"GO:0055038"(recycling endosome membrane)|uniprotkb:P10321(see-also)|rcsb pdb:1EFX|ensembl:ENST00000457903|ensembl:ENSP00000390851|ensembl:ENSG00000225691|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0009986"(cell surface)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0046977"(TAP binding)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0045087"(innate immune response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050776"(regulation of immune response)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR036179|interpro:IPR037055 - comment:mint no-uniprot-update:|caution:"The protein could not be merged with EBI-1051396 because of some conflicts with the protein sequence (features which cannot be shifted)." figure legend:Fig 1Ai-2 and text|comment:"C0302, C0303, C0304 (canonical entry) alleles all bind"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2017/08/24 rogid:8lycFqdUAUK1Ww2NpLHNFtFPlZ49606 rogid:JFeUsl+FLKQrUF6Miog4kKzX3aE9606 rigid:G0XOmHmhSlcmzuzi1j/yE53qKsU false sufficient binding region:22-242|fc-igg tag:c-c variant:115-115|variant:119-119,140-140 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P43626 uniprotkb:P10321 intact:EBI-8684277|uniprotkb:Q6IST4|intact:MINT-8013645|uniprotkb:Q32WE6|uniprotkb:O43470|ensembl:ENSP00000478232|ensembl:ENSP00000478263|ensembl:ENSP00000479363|ensembl:ENSP00000482120|ensembl:ENSP00000484361|ensembl:ENSP00000484559|ensembl:ENSP00000291633 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 psi-mi:ki2l1_human(display_long)|uniprotkb:KIR2DL1(gene name)|psi-mi:KIR2DL1(display_short)|uniprotkb:CD158 antigen-like family member A(gene name synonym)|uniprotkb:CD158A(gene name synonym)|uniprotkb:NKAT1(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 1(gene name synonym)|uniprotkb:p58 natural killer cell receptor clones CL-42/47.11(gene name synonym)|uniprotkb:p58.1 MHC class-I-specific NK receptor(gene name synonym) psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16372128|imex:IM-26182-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055033.2|ensembl:ENSG00000125498(gene)|ensembl:ENSG00000273794(gene)|ensembl:ENSG00000276625(gene)|ensembl:ENSG00000277833(gene)|ensembl:ENSG00000278495(gene)|ensembl:ENSG00000278738(gene)|ensembl:ENSG00000278821(gene)|ensembl:ENST00000291633(transcript)|ensembl:ENST00000611611(transcript)|ensembl:ENST00000615920(transcript)|ensembl:ENST00000617376(transcript)|ensembl:ENST00000618563(transcript)|ensembl:ENST00000620449(transcript)|ensembl:ENST00000622463(transcript)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IM9|rcsb pdb:1NKR|reactome:R-HSA-198933 refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 - comment:mint - figure legend:Fig 1Ai-3 and text|comment:C0702 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:8lycFqdUAUK1Ww2NpLHNFtFPlZ49606 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rigid:P0WYRZRAbNwTALcykoeA5rWQ8b8 false sufficient binding region:22-242|fc-igg tag:c-c - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P43626 uniprotkb:P10321 intact:EBI-8684277|uniprotkb:Q6IST4|intact:MINT-8013645|uniprotkb:Q32WE6|uniprotkb:O43470|ensembl:ENSP00000478232|ensembl:ENSP00000478263|ensembl:ENSP00000479363|ensembl:ENSP00000482120|ensembl:ENSP00000484361|ensembl:ENSP00000484559|ensembl:ENSP00000291633 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 psi-mi:ki2l1_human(display_long)|uniprotkb:KIR2DL1(gene name)|psi-mi:KIR2DL1(display_short)|uniprotkb:CD158 antigen-like family member A(gene name synonym)|uniprotkb:CD158A(gene name synonym)|uniprotkb:NKAT1(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 1(gene name synonym)|uniprotkb:p58 natural killer cell receptor clones CL-42/47.11(gene name synonym)|uniprotkb:p58.1 MHC class-I-specific NK receptor(gene name synonym) psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16372201|imex:IM-26182-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055033.2|ensembl:ENSG00000125498(gene)|ensembl:ENSG00000273794(gene)|ensembl:ENSG00000276625(gene)|ensembl:ENSG00000277833(gene)|ensembl:ENSG00000278495(gene)|ensembl:ENSG00000278738(gene)|ensembl:ENSG00000278821(gene)|ensembl:ENST00000291633(transcript)|ensembl:ENST00000611611(transcript)|ensembl:ENST00000615920(transcript)|ensembl:ENST00000617376(transcript)|ensembl:ENST00000618563(transcript)|ensembl:ENST00000620449(transcript)|ensembl:ENST00000622463(transcript)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IM9|rcsb pdb:1NKR|reactome:R-HSA-198933 refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 - comment:mint - figure legend:Fig 1Ai-4 and text|comment:C0801 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:8lycFqdUAUK1Ww2NpLHNFtFPlZ49606 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rigid:P0WYRZRAbNwTALcykoeA5rWQ8b8 false sufficient binding region:22-242|fc-igg tag:c-c - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P43626 uniprotkb:P10321 intact:EBI-8684277|uniprotkb:Q6IST4|intact:MINT-8013645|uniprotkb:Q32WE6|uniprotkb:O43470|ensembl:ENSP00000478232|ensembl:ENSP00000478263|ensembl:ENSP00000479363|ensembl:ENSP00000482120|ensembl:ENSP00000484361|ensembl:ENSP00000484559|ensembl:ENSP00000291633 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 psi-mi:ki2l1_human(display_long)|uniprotkb:KIR2DL1(gene name)|psi-mi:KIR2DL1(display_short)|uniprotkb:CD158 antigen-like family member A(gene name synonym)|uniprotkb:CD158A(gene name synonym)|uniprotkb:NKAT1(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 1(gene name synonym)|uniprotkb:p58 natural killer cell receptor clones CL-42/47.11(gene name synonym)|uniprotkb:p58.1 MHC class-I-specific NK receptor(gene name synonym) psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16372214|imex:IM-26182-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055033.2|ensembl:ENSG00000125498(gene)|ensembl:ENSG00000273794(gene)|ensembl:ENSG00000276625(gene)|ensembl:ENSG00000277833(gene)|ensembl:ENSG00000278495(gene)|ensembl:ENSG00000278738(gene)|ensembl:ENSG00000278821(gene)|ensembl:ENST00000291633(transcript)|ensembl:ENST00000611611(transcript)|ensembl:ENST00000615920(transcript)|ensembl:ENST00000617376(transcript)|ensembl:ENST00000618563(transcript)|ensembl:ENST00000620449(transcript)|ensembl:ENST00000622463(transcript)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IM9|rcsb pdb:1NKR|reactome:R-HSA-198933 refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 - comment:mint - figure legend:Fig 1Ai-5 and text|comment:C1203 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:8lycFqdUAUK1Ww2NpLHNFtFPlZ49606 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rigid:P0WYRZRAbNwTALcykoeA5rWQ8b8 false sufficient binding region:22-242|fc-igg tag:c-c variant:121-121 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P43626 uniprotkb:P10321 intact:EBI-8684277|uniprotkb:Q6IST4|intact:MINT-8013645|uniprotkb:Q32WE6|uniprotkb:O43470|ensembl:ENSP00000478232|ensembl:ENSP00000478263|ensembl:ENSP00000479363|ensembl:ENSP00000482120|ensembl:ENSP00000484361|ensembl:ENSP00000484559|ensembl:ENSP00000291633 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 psi-mi:ki2l1_human(display_long)|uniprotkb:KIR2DL1(gene name)|psi-mi:KIR2DL1(display_short)|uniprotkb:CD158 antigen-like family member A(gene name synonym)|uniprotkb:CD158A(gene name synonym)|uniprotkb:NKAT1(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 1(gene name synonym)|uniprotkb:p58 natural killer cell receptor clones CL-42/47.11(gene name synonym)|uniprotkb:p58.1 MHC class-I-specific NK receptor(gene name synonym) psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16372347|imex:IM-26182-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055033.2|ensembl:ENSG00000125498(gene)|ensembl:ENSG00000273794(gene)|ensembl:ENSG00000276625(gene)|ensembl:ENSG00000277833(gene)|ensembl:ENSG00000278495(gene)|ensembl:ENSG00000278738(gene)|ensembl:ENSG00000278821(gene)|ensembl:ENST00000291633(transcript)|ensembl:ENST00000611611(transcript)|ensembl:ENST00000615920(transcript)|ensembl:ENST00000617376(transcript)|ensembl:ENST00000618563(transcript)|ensembl:ENST00000620449(transcript)|ensembl:ENST00000622463(transcript)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IM9|rcsb pdb:1NKR|reactome:R-HSA-198933 refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 - comment:mint - figure legend:Fig 1Ai-6 and text|comment:C1601 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:8lycFqdUAUK1Ww2NpLHNFtFPlZ49606 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rigid:P0WYRZRAbNwTALcykoeA5rWQ8b8 false sufficient binding region:22-242|fc-igg tag:c-c - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P43626 uniprotkb:P01889 intact:EBI-8684277|uniprotkb:Q6IST4|intact:MINT-8013645|uniprotkb:Q32WE6|uniprotkb:O43470|ensembl:ENSP00000478232|ensembl:ENSP00000478263|ensembl:ENSP00000479363|ensembl:ENSP00000482120|ensembl:ENSP00000484361|ensembl:ENSP00000484559|ensembl:ENSP00000291633 intact:EBI-1046513|ensembl:ENSP00000399168|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6 psi-mi:ki2l1_human(display_long)|uniprotkb:KIR2DL1(gene name)|psi-mi:KIR2DL1(display_short)|uniprotkb:CD158 antigen-like family member A(gene name synonym)|uniprotkb:CD158A(gene name synonym)|uniprotkb:NKAT1(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 1(gene name synonym)|uniprotkb:p58 natural killer cell receptor clones CL-42/47.11(gene name synonym)|uniprotkb:p58.1 MHC class-I-specific NK receptor(gene name synonym) psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16372360|imex:IM-26182-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055033.2|ensembl:ENSG00000125498(gene)|ensembl:ENSG00000273794(gene)|ensembl:ENSG00000276625(gene)|ensembl:ENSG00000277833(gene)|ensembl:ENSG00000278495(gene)|ensembl:ENSG00000278738(gene)|ensembl:ENSG00000278821(gene)|ensembl:ENST00000291633(transcript)|ensembl:ENST00000611611(transcript)|ensembl:ENST00000615920(transcript)|ensembl:ENST00000617376(transcript)|ensembl:ENST00000618563(transcript)|ensembl:ENST00000620449(transcript)|ensembl:ENST00000622463(transcript)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IM9|rcsb pdb:1NKR|reactome:R-HSA-198933 rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2A83|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:2AK4|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:2AXF|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:2H6P|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|interpro:IPR037055|rcsb pdb:1A1M|rcsb pdb:1A1N|interpro:IPR036179|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4G9F|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5IEK|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5IM7|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5INC|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:5T6X|rcsb pdb:6BXQ|rcsb pdb:5T6Y|rcsb pdb:6D29|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|ensembl:ENSG00000234745(gene)|ensembl:ENST00000412585(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6MTL|refseq:NP_005505.2 - comment:mint - figure legend:Fig 1Ai-7 and text|comment:B4601 allele|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:8lycFqdUAUK1Ww2NpLHNFtFPlZ49606 rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606 rigid:QZBYxsuthN8A1iZddxRcK9kvbI8 false sufficient binding region:22-242|fc-igg tag:c-c - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P43626 uniprotkb:P01889 intact:EBI-8684277|uniprotkb:Q6IST4|intact:MINT-8013645|uniprotkb:Q32WE6|uniprotkb:O43470|ensembl:ENSP00000478232|ensembl:ENSP00000478263|ensembl:ENSP00000479363|ensembl:ENSP00000482120|ensembl:ENSP00000484361|ensembl:ENSP00000484559|ensembl:ENSP00000291633 intact:EBI-1046513|ensembl:ENSP00000399168|uniprotkb:O62901|uniprotkb:O95730|uniprotkb:O98140|uniprotkb:P79542|uniprotkb:Q95369|uniprotkb:Q95J00|uniprotkb:Q9GJ20|uniprotkb:Q9MY78|uniprotkb:Q9MYF4|uniprotkb:Q9TQH6|uniprotkb:Q9TQM2|uniprotkb:Q9UQT0|intact:EBI-1049793|intact:EBI-6163549|intact:EBI-6163552|intact:EBI-6163582|intact:EBI-6163570|intact:EBI-6163579|intact:EBI-6163555|intact:EBI-9978548|intact:EBI-1047909|intact:EBI-8770324|uniprotkb:A0A2I6Q7B5|uniprotkb:B0V0B8|uniprotkb:G3GN01|uniprotkb:O02862|uniprotkb:O02956|uniprotkb:O02957|uniprotkb:O02960|uniprotkb:O19555|uniprotkb:O19556|uniprotkb:O19595|uniprotkb:O19615|uniprotkb:O19624|uniprotkb:O78163|uniprotkb:O78172|intact:EBI-1054175|uniprotkb:O19625|uniprotkb:O19627|uniprotkb:O19641|uniprotkb:O19651|uniprotkb:O19675|uniprotkb:O19692|uniprotkb:O19758|uniprotkb:O19779|uniprotkb:O19783|uniprotkb:O46702|uniprotkb:O62897|uniprotkb:O62915|uniprotkb:O62917|uniprotkb:O62919|uniprotkb:O77933|uniprotkb:O77959|uniprotkb:O78053|uniprotkb:O78138|uniprotkb:O78160|uniprotkb:O78173|uniprotkb:O78180|uniprotkb:O78217|uniprotkb:P01890|uniprotkb:P03989|uniprotkb:P10317|uniprotkb:P10318|uniprotkb:P10319|uniprotkb:P10320|uniprotkb:P18463|uniprotkb:P18464|uniprotkb:P18465|uniprotkb:P19373|uniprotkb:P30460|uniprotkb:P30461|uniprotkb:P30462|uniprotkb:P30463|uniprotkb:P30464|uniprotkb:P30465|uniprotkb:P30466|uniprotkb:P30467|uniprotkb:P30468|uniprotkb:P30469|uniprotkb:P30470|uniprotkb:P30471|uniprotkb:P30472|uniprotkb:P30473|uniprotkb:P30474|uniprotkb:P30475|uniprotkb:P30476|uniprotkb:P30477|uniprotkb:P30478|uniprotkb:P30479|uniprotkb:P30480|uniprotkb:P30481|uniprotkb:Q29693|uniprotkb:Q29695|uniprotkb:Q29697|uniprotkb:Q29718|uniprotkb:Q29742|uniprotkb:Q29749|uniprotkb:Q29762|uniprotkb:Q29764|uniprotkb:Q29829|uniprotkb:Q29836|uniprotkb:Q29842|uniprotkb:Q29845|uniprotkb:Q29846|uniprotkb:Q29847|uniprotkb:Q29848|uniprotkb:Q29850|uniprotkb:Q29851|uniprotkb:Q29852|uniprotkb:P30482|uniprotkb:P30483|uniprotkb:P30484|uniprotkb:P30485|uniprotkb:P30486|uniprotkb:P30487|uniprotkb:P30488|uniprotkb:P30489|uniprotkb:P30490|uniprotkb:P30491|uniprotkb:P30492|uniprotkb:P30493|uniprotkb:P30494|uniprotkb:P30495|uniprotkb:P30496|uniprotkb:P30497|uniprotkb:P30498|uniprotkb:P30513|uniprotkb:P30685|uniprotkb:P79489|uniprotkb:P79490|uniprotkb:P79496|uniprotkb:P79504|uniprotkb:P79523|uniprotkb:P79524|uniprotkb:P79555|uniprotkb:Q04826|uniprotkb:Q08136|uniprotkb:Q29633|uniprotkb:Q29636|uniprotkb:Q29638|uniprotkb:Q29661|uniprotkb:Q29665|uniprotkb:Q29678|uniprotkb:Q29679|uniprotkb:Q29681|uniprotkb:Q29935|uniprotkb:Q29936|uniprotkb:Q29940|uniprotkb:Q29953|uniprotkb:Q29961|uniprotkb:Q29982|intact:EBI-4289931|intact:EBI-7382650|intact:MINT-144207|intact:EBI-7245379|intact:MINT-1195012|intact:EBI-1059117|intact:EBI-4289845|uniprotkb:Q29854|uniprotkb:Q29855|uniprotkb:Q29857|uniprotkb:Q29858|uniprotkb:Q29861|uniprotkb:Q29924|uniprotkb:Q29925|uniprotkb:Q29933|uniprotkb:Q8MHN4|uniprotkb:Q30173|uniprotkb:Q30198|uniprotkb:Q31603|uniprotkb:Q31610|uniprotkb:Q31612|uniprotkb:Q31613|uniprotkb:Q546L8|uniprotkb:Q546M4|uniprotkb:Q5JP37|uniprotkb:Q5QT24|uniprotkb:Q5RIP1|uniprotkb:Q5SRJ2|uniprotkb:Q5TK76|uniprotkb:Q5TK77|uniprotkb:Q860I4|uniprotkb:Q861B5|uniprotkb:Q8HWF0|uniprotkb:Q8MGQ3|uniprotkb:Q8SNC5|uniprotkb:Q95343|uniprotkb:Q95344|uniprotkb:Q95365|uniprotkb:Q95392|uniprotkb:Q95HA3|uniprotkb:Q95HA8|uniprotkb:Q95HM9|uniprotkb:Q95IA6|uniprotkb:Q95IB8|uniprotkb:Q95IH5|uniprotkb:Q96IT9|uniprotkb:Q9BCM6|uniprotkb:Q9BCM7|uniprotkb:Q9BCM8|uniprotkb:Q9BD06|uniprotkb:Q9BD38|uniprotkb:Q9BD43|uniprotkb:Q9GIL3|uniprotkb:Q9GIM3|uniprotkb:Q9GIX1|uniprotkb:Q9GIY5|uniprotkb:Q9GIZ0|uniprotkb:Q9GIZ9|uniprotkb:Q9GJ00|uniprotkb:Q9GJ17|uniprotkb:Q9GJ23|uniprotkb:Q9GJ31|uniprotkb:Q9GJF0|uniprotkb:Q9GJM7|uniprotkb:Q9MX21|uniprotkb:Q9MY37|uniprotkb:Q9MY42|uniprotkb:Q9MY43|uniprotkb:Q9MY61|uniprotkb:Q9MY75|uniprotkb:Q9MY79|uniprotkb:Q9MY84|uniprotkb:Q9MY92|uniprotkb:Q9MY93|uniprotkb:Q9MY94|uniprotkb:Q9MYB8|uniprotkb:Q9MYC3|uniprotkb:Q9MYC7|uniprotkb:Q9MYG1|uniprotkb:Q9TP35|uniprotkb:Q9UQS8|uniprotkb:Q9TP36|uniprotkb:Q9TP37|uniprotkb:Q9TP95|uniprotkb:Q9TPQ7|uniprotkb:Q9TPQ9|uniprotkb:Q9TPR2|uniprotkb:Q9TPR4|uniprotkb:Q9TPS6|uniprotkb:Q9TPT2|uniprotkb:Q9TPT4|uniprotkb:Q9TPT6|uniprotkb:Q9TPV2|uniprotkb:Q9TQG1|uniprotkb:Q9TQH3|uniprotkb:Q9TQH7|uniprotkb:Q9TQH8|uniprotkb:Q9TQH9|uniprotkb:Q9TQN4|uniprotkb:Q9TQN6 psi-mi:ki2l1_human(display_long)|uniprotkb:KIR2DL1(gene name)|psi-mi:KIR2DL1(display_short)|uniprotkb:CD158 antigen-like family member A(gene name synonym)|uniprotkb:CD158A(gene name synonym)|uniprotkb:NKAT1(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 1(gene name synonym)|uniprotkb:p58 natural killer cell receptor clones CL-42/47.11(gene name synonym)|uniprotkb:p58.1 MHC class-I-specific NK receptor(gene name synonym) psi-mi:hlab_human(display_long)|uniprotkb:Human leukocyte antigen B(gene name synonym)|uniprotkb:HLA-B(gene name)|psi-mi:HLA-B(display_short)|uniprotkb:HLAB(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-16372369|imex:IM-26182-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055033.2|ensembl:ENSG00000125498(gene)|ensembl:ENSG00000273794(gene)|ensembl:ENSG00000276625(gene)|ensembl:ENSG00000277833(gene)|ensembl:ENSG00000278495(gene)|ensembl:ENSG00000278738(gene)|ensembl:ENSG00000278821(gene)|ensembl:ENST00000291633(transcript)|ensembl:ENST00000611611(transcript)|ensembl:ENST00000615920(transcript)|ensembl:ENST00000617376(transcript)|ensembl:ENST00000618563(transcript)|ensembl:ENST00000620449(transcript)|ensembl:ENST00000622463(transcript)|go:"GO:0002769"(natural killer cell inhibitory signaling pathway)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IM9|rcsb pdb:1NKR|reactome:R-HSA-198933 rcsb pdb:2HJL|rcsb pdb:2NW3|rcsb pdb:2A83|rcsb pdb:2NX5|rcsb pdb:2RFX|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3C9N|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3DTX|rcsb pdb:2AK4|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:2AXF|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3HCV|rcsb pdb:2AXG|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3KPO|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3KXF|rcsb pdb:3L3D|rcsb pdb:2H6P|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3LN5|rcsb pdb:3LV3|rcsb pdb:3MV7|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3UPR|rcsb pdb:3VCL|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3VRJ|rcsb pdb:3W39|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|interpro:IPR037055|rcsb pdb:1A1M|rcsb pdb:1A1N|interpro:IPR036179|rcsb pdb:1A1O|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1CG9|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1HSA|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1K5N|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGT|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1ZHK|rcsb pdb:1ZHL|rcsb pdb:1ZSD|rcsb pdb:4JQV|rcsb pdb:4JQX|rcsb pdb:4LCY|rcsb pdb:4LNR|rcsb pdb:4MJI|rcsb pdb:4G9F|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PR5|rcsb pdb:4PRN|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4XXC|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5TXS|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5IEK|rcsb pdb:5VUF|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5IM7|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5INC|rcsb pdb:6AT5|rcsb pdb:6AVF|rcsb pdb:5IND|rcsb pdb:5T6W|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:5T6X|rcsb pdb:6BXQ|rcsb pdb:5T6Y|rcsb pdb:6D29|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:6D2B|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|ensembl:ENSG00000234745(gene)|ensembl:ENST00000412585(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0002667"(regulation of T cell anergy)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:6MTM|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6P2F|rcsb pdb:6P2S|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VMX|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LGD|rcsb pdb:7LGT|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:6MTL|refseq:NP_005505.2 - comment:mint - figure legend:Fig 1Ai-8 and text|comment:"B7301 allele (canonical)"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:8lycFqdUAUK1Ww2NpLHNFtFPlZ49606 rogid:NlO2PZ/66RypUzj8Euht3hRq8H89606 rigid:QZBYxsuthN8A1iZddxRcK9kvbI8 false sufficient binding region:22-242|fc-igg tag:c-c - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P61769 uniprotkb:P10321 intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191|ensembl:ENSP00000453350|ensembl:ENSP00000481426|ensembl:ENSP00000488321|ensembl:ENSP00000488548|ensembl:ENSP00000497910 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name) psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16372599|imex:IM-26182-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5INC|rcsb pdb:5TXS|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5U16|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6D2B|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6PTE|rcsb pdb:6P2F|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VB4|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7C9V|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MKB|rcsb pdb:7NUI|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-977225|reactome:R-HSA-983170|ensembl:ENSG00000166710(gene)|ensembl:ENSG00000273686(gene)|ensembl:ENST00000559916(transcript)|ensembl:ENST00000561424(transcript)|ensembl:ENST00000617605(transcript)|ensembl:ENST00000631573(transcript)|ensembl:ENST00000631728(transcript)|ensembl:ENST00000648006(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0005925"(focal adhesion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1T20|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UR7|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1ZHK|rcsb pdb:1T1W|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:1T1X|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:1T1Y|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:1T1Z|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|refseq:NP_004039.1|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3KPO|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3KXF|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3KYN|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:3T8X|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4L3E|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:4XXC|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|dip:DIP-6055N refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 - - - figure legend:3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rigid:JCZV0L60O3Ng8D2U9bfWzL2SnuI false sufficient binding region:?-? sufficient binding region:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P61769 uniprotkb:Q14954 intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191|ensembl:ENSP00000453350|ensembl:ENSP00000481426|ensembl:ENSP00000488321|ensembl:ENSP00000488548|ensembl:ENSP00000497910 intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711|ensembl:ENSP00000481628|ensembl:ENSP00000482060|ensembl:ENSP00000482170|ensembl:ENSP00000482900|ensembl:ENSP00000483434|ensembl:ENSP00000491232|ensembl:ENSP00000492239|ensembl:ENSP00000492347|ensembl:ENSP00000494266|ensembl:ENSP00000494623|ensembl:ENSP00000495438 psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name) psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16372599|imex:IM-26182-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5INC|rcsb pdb:5TXS|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5U16|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6D2B|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6PTE|rcsb pdb:6P2F|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VB4|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7C9V|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MKB|rcsb pdb:7NUI|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-977225|reactome:R-HSA-983170|ensembl:ENSG00000166710(gene)|ensembl:ENSG00000273686(gene)|ensembl:ENST00000559916(transcript)|ensembl:ENST00000561424(transcript)|ensembl:ENST00000617605(transcript)|ensembl:ENST00000631573(transcript)|ensembl:ENST00000631728(transcript)|ensembl:ENST00000648006(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0005925"(focal adhesion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1T20|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UR7|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1ZHK|rcsb pdb:1T1W|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:1T1X|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:1T1Y|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:1T1Z|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|refseq:NP_004039.1|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3KPO|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3KXF|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3KYN|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:3T8X|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4L3E|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:4XXC|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|dip:DIP-6055N refseq:NP_055327.1|ensembl:ENSG00000273517(gene)|ensembl:ENSG00000273603(gene)|ensembl:ENSG00000275421(gene)|ensembl:ENSG00000276327(gene)|ensembl:ENSG00000278120(gene)|ensembl:ENSG00000278304(gene)|ensembl:ENSG00000284120(gene)|ensembl:ENSG00000284150(gene)|ensembl:ENSG00000284560(gene)|ensembl:ENST00000611996(transcript)|ensembl:ENST00000612447(transcript)|ensembl:ENST00000617661(transcript)|ensembl:ENST00000618071(transcript)|ensembl:ENST00000621207(transcript)|ensembl:ENST00000622039(transcript)|ensembl:ENST00000638832(transcript)|ensembl:ENST00000639093(transcript)|ensembl:ENST00000639232(transcript)|ensembl:ENST00000643062(transcript)|ensembl:ENST00000644318(transcript)|ensembl:ENST00000645834(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 - - - figure legend:3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606 rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606 rigid:JCZV0L60O3Ng8D2U9bfWzL2SnuI false sufficient binding region:?-? sufficient binding region:22..22-245..245|tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P61769 intact:EBI-16372622 intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191|ensembl:ENSP00000453350|ensembl:ENSP00000481426|ensembl:ENSP00000488321|ensembl:ENSP00000488548|ensembl:ENSP00000497910 - psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name) psi-mi:peptide-x(display_short)|psi-mi:EBI-16372622(display_long) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16372599|imex:IM-26182-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5INC|rcsb pdb:5TXS|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5U16|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6D2B|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6PTE|rcsb pdb:6P2F|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VB4|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7C9V|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MKB|rcsb pdb:7NUI|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-977225|reactome:R-HSA-983170|ensembl:ENSG00000166710(gene)|ensembl:ENSG00000273686(gene)|ensembl:ENST00000559916(transcript)|ensembl:ENST00000561424(transcript)|ensembl:ENST00000617605(transcript)|ensembl:ENST00000631573(transcript)|ensembl:ENST00000631728(transcript)|ensembl:ENST00000648006(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0005925"(focal adhesion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1T20|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UR7|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1ZHK|rcsb pdb:1T1W|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:1T1X|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:1T1Y|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:1T1Z|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|refseq:NP_004039.1|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3KPO|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3KXF|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3KYN|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:3T8X|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4L3E|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:4XXC|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|dip:DIP-6055N - - - - figure legend:3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606 rogid:3rs+twN73HOyUBaE1d4QZw6SxHk-2 rigid:JCZV0L60O3Ng8D2U9bfWzL2SnuI false sufficient binding region:?-? red fluorescent protein tag:?-?|sufficient binding region:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P61769 uniprotkb:P10321 intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191|ensembl:ENSP00000453350|ensembl:ENSP00000481426|ensembl:ENSP00000488321|ensembl:ENSP00000488548|ensembl:ENSP00000497910 intact:EBI-1051396|uniprotkb:O78067|uniprotkb:O78072|uniprotkb:O78090|uniprotkb:O78149|uniprotkb:Q29921|uniprotkb:Q9UM42|intact:EBI-13916949|uniprotkb:O02863|intact:EBI-6163576|intact:EBI-4400689|intact:EBI-6163558|uniprotkb:O02864|uniprotkb:O02865|uniprotkb:O02866|uniprotkb:O02958|uniprotkb:O19505|uniprotkb:O19652|uniprotkb:O19676|uniprotkb:O62879|uniprotkb:O62882|uniprotkb:O62883|uniprotkb:O62888|uniprotkb:O78060|uniprotkb:O78061|uniprotkb:O78062|uniprotkb:O78063|uniprotkb:O78068|uniprotkb:O78069|uniprotkb:O78083|uniprotkb:O78091|uniprotkb:O78165|uniprotkb:O78166|uniprotkb:O78178|uniprotkb:O78202|uniprotkb:O78203|uniprotkb:O78211|uniprotkb:O78214|uniprotkb:P04222|uniprotkb:P30499|uniprotkb:P30500|uniprotkb:P30501|uniprotkb:P30502|uniprotkb:P30503|uniprotkb:P30504|uniprotkb:P30505|uniprotkb:P30506|uniprotkb:P30507|uniprotkb:P30508|uniprotkb:P30509|uniprotkb:P30510|uniprotkb:P79498|uniprotkb:Q07000|uniprotkb:Q29631|uniprotkb:Q29641|uniprotkb:Q29643|uniprotkb:Q29652|uniprotkb:Q29743|uniprotkb:Q29768|uniprotkb:Q29862|uniprotkb:Q29864|uniprotkb:Q29865|uniprotkb:Q29867|uniprotkb:Q29959|uniprotkb:Q29960|uniprotkb:Q29963|uniprotkb:Q29986|uniprotkb:Q29989|uniprotkb:Q9MY74|uniprotkb:Q9MYI3|uniprotkb:Q9TNN7|uniprotkb:Q9TNZ8|uniprotkb:Q9TPS4|uniprotkb:Q9TPV8|uniprotkb:Q9TPX2|uniprotkb:Q9TQB4|uniprotkb:Q9TQJ5|uniprotkb:Q9TQP9|uniprotkb:Q9UM32|uniprotkb:Q9UM33|uniprotkb:Q9UQS9|uniprotkb:Q29990|uniprotkb:Q29991|uniprotkb:Q29992|uniprotkb:Q29993|uniprotkb:Q30192|uniprotkb:Q31605|uniprotkb:Q31627|uniprotkb:Q9GJ33|uniprotkb:Q9MY30|uniprotkb:Q860R1|uniprotkb:Q860R2|uniprotkb:Q95463|uniprotkb:Q95603|uniprotkb:Q95604|uniprotkb:Q99528|uniprotkb:Q9BD28|uniprotkb:Q9GIK4|uniprotkb:Q9GIK8|intact:EBI-9978491|intact:EBI-3905378|intact:EBI-6163573|intact:EBI-1058803|intact:EBI-13917304|uniprotkb:Q9MY31|uniprotkb:Q9MY35|uniprotkb:Q9MY49|ensembl:ENSP00000365402 psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name) psi-mi:hlac_human(display_long)|uniprotkb:HLA-Cw(gene name synonym)|uniprotkb:Human leukocyte antigen C(gene name synonym)|uniprotkb:HLAC(gene name synonym)|uniprotkb:HLA-C(gene name)|psi-mi:HLA-C(display_short) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16372680|imex:IM-26182-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5INC|rcsb pdb:5TXS|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5U16|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6D2B|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6PTE|rcsb pdb:6P2F|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VB4|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7C9V|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MKB|rcsb pdb:7NUI|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-977225|reactome:R-HSA-983170|ensembl:ENSG00000166710(gene)|ensembl:ENSG00000273686(gene)|ensembl:ENST00000559916(transcript)|ensembl:ENST00000561424(transcript)|ensembl:ENST00000617605(transcript)|ensembl:ENST00000631573(transcript)|ensembl:ENST00000631728(transcript)|ensembl:ENST00000648006(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0005925"(focal adhesion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1T20|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UR7|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1ZHK|rcsb pdb:1T1W|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:1T1X|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:1T1Y|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:1T1Z|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|refseq:NP_004039.1|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3KPO|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3KXF|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3KYN|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:3T8X|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4L3E|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:4XXC|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|dip:DIP-6055N refseq:NP_002108.4|ensembl:ENSG00000204525(gene)|ensembl:ENST00000376228(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0045087"(innate immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037055|mint:P10321|rcsb pdb:1EFX|rcsb pdb:1IM9|rcsb pdb:1QQD|rcsb pdb:3BZF|rcsb pdb:4NT6|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:6JTO|rcsb pdb:6PA1|rcsb pdb:6PAG|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170 - - - figure legend:5C|comment:"KIR2DS1(+) KIR2DL1(−) NK cell clones"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606 rogid:VYYWt9SpNZEuu0jZkdCHEe65lAE9606 rigid:JCZV0L60O3Ng8D2U9bfWzL2SnuI false sufficient binding region:?-? sufficient binding region:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P61769 uniprotkb:Q14954 intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191|ensembl:ENSP00000453350|ensembl:ENSP00000481426|ensembl:ENSP00000488321|ensembl:ENSP00000488548|ensembl:ENSP00000497910 intact:EBI-2865976|uniprotkb:O43471|uniprotkb:K7QUS8|ensembl:ENSP00000478711|ensembl:ENSP00000481628|ensembl:ENSP00000482060|ensembl:ENSP00000482170|ensembl:ENSP00000482900|ensembl:ENSP00000483434|ensembl:ENSP00000491232|ensembl:ENSP00000492239|ensembl:ENSP00000492347|ensembl:ENSP00000494266|ensembl:ENSP00000494623|ensembl:ENSP00000495438 psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name) psi-mi:ki2s1_human(display_long)|uniprotkb:KIR2DS1(gene name)|psi-mi:KIR2DS1(display_short)|uniprotkb:CD158H(gene name synonym)|uniprotkb:CD158 antigen-like family member H(gene name synonym)|uniprotkb:MHC class I NK cell receptor Eb6 ActI(gene name synonym) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16372680|imex:IM-26182-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5INC|rcsb pdb:5TXS|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5U16|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6D2B|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6PTE|rcsb pdb:6P2F|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VB4|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7C9V|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MKB|rcsb pdb:7NUI|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-977225|reactome:R-HSA-983170|ensembl:ENSG00000166710(gene)|ensembl:ENSG00000273686(gene)|ensembl:ENST00000559916(transcript)|ensembl:ENST00000561424(transcript)|ensembl:ENST00000617605(transcript)|ensembl:ENST00000631573(transcript)|ensembl:ENST00000631728(transcript)|ensembl:ENST00000648006(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0005925"(focal adhesion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1T20|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UR7|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1ZHK|rcsb pdb:1T1W|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:1T1X|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:1T1Y|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:1T1Z|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|refseq:NP_004039.1|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3KPO|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3KXF|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3KYN|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:3T8X|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4L3E|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:4XXC|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|dip:DIP-6055N refseq:NP_055327.1|ensembl:ENSG00000273517(gene)|ensembl:ENSG00000273603(gene)|ensembl:ENSG00000275421(gene)|ensembl:ENSG00000276327(gene)|ensembl:ENSG00000278120(gene)|ensembl:ENSG00000278304(gene)|ensembl:ENSG00000284120(gene)|ensembl:ENSG00000284150(gene)|ensembl:ENSG00000284560(gene)|ensembl:ENST00000611996(transcript)|ensembl:ENST00000612447(transcript)|ensembl:ENST00000617661(transcript)|ensembl:ENST00000618071(transcript)|ensembl:ENST00000621207(transcript)|ensembl:ENST00000622039(transcript)|ensembl:ENST00000638832(transcript)|ensembl:ENST00000639093(transcript)|ensembl:ENST00000639232(transcript)|ensembl:ENST00000643062(transcript)|ensembl:ENST00000644318(transcript)|ensembl:ENST00000645834(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 - - - figure legend:5C|comment:"KIR2DS1(+) KIR2DL1(−) NK cell clones"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606 rogid:crOV0FYXEakUxq57/gP4Rbei6+g9606 rigid:JCZV0L60O3Ng8D2U9bfWzL2SnuI false sufficient binding region:?-? - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P61769 intact:EBI-16372622 intact:EBI-714718|uniprotkb:P01884|uniprotkb:Q9UDF4|uniprotkb:Q540F8|uniprotkb:Q6IAT8|uniprotkb:Q9UCK0|uniprotkb:Q9UD48|ensembl:ENSP00000453191|ensembl:ENSP00000453350|ensembl:ENSP00000481426|ensembl:ENSP00000488321|ensembl:ENSP00000488548|ensembl:ENSP00000497910 - psi-mi:b2mg_human(display_long)|uniprotkb:B2M(gene name)|psi-mi:B2M(display_short)|uniprotkb:CDABP0092(orf name)|uniprotkb:HDCMA22P(orf name) psi-mi:peptide-x(display_short)|psi-mi:EBI-16372622(display_long) psi-mi:"MI:0054"(fluorescence-activated cell sorting) Chapel et al. (2017) pubmed:28546555|imex:IM-26182 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-16372680|imex:IM-26182-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) rcsb pdb:5KNM|rcsb pdb:5L2J|rcsb pdb:5L2K|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:5N1Y|rcsb pdb:5N6B|rcsb pdb:5NHT|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5NMG|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:5NQ1|rcsb pdb:5NQ3|rcsb pdb:5NQK|rcsb pdb:5OPI|rcsb pdb:5SWQ|rcsb pdb:5T6W|rcsb pdb:5T6X|rcsb pdb:5T6Y|rcsb pdb:5T6Z|rcsb pdb:5T70|rcsb pdb:5TEZ|rcsb pdb:5HYJ|rcsb pdb:5IB1|rcsb pdb:5IB2|rcsb pdb:5IB3|rcsb pdb:5IB4|rcsb pdb:5IB5|rcsb pdb:5IEH|rcsb pdb:5IEK|rcsb pdb:5IM7|rcsb pdb:5TRZ|rcsb pdb:5TS1|rcsb pdb:5INC|rcsb pdb:5TXS|rcsb pdb:5IND|rcsb pdb:5IRO|rcsb pdb:5ISZ|rcsb pdb:5IUE|rcsb pdb:5J1A|rcsb pdb:5U16|rcsb pdb:5JHD|rcsb pdb:5JZI|rcsb pdb:5U17|rcsb pdb:5U1R|rcsb pdb:5U2V|rcsb pdb:5U6Q|rcsb pdb:5U72|rcsb pdb:5U98|rcsb pdb:5V5L|rcsb pdb:5V5M|rcsb pdb:5VGD|rcsb pdb:5VGE|rcsb pdb:5VUD|rcsb pdb:5VUE|rcsb pdb:5VUF|rcsb pdb:5VVP|rcsb pdb:5VWD|rcsb pdb:5VWF|rcsb pdb:5VWH|rcsb pdb:5VWJ|rcsb pdb:5VZ5|rcsb pdb:5W1V|rcsb pdb:5W1W|rcsb pdb:5W67|rcsb pdb:5W69|rcsb pdb:5W6A|rcsb pdb:5WER|rcsb pdb:5WHK|rcsb pdb:5WJL|rcsb pdb:5WJN|rcsb pdb:5WKE|rcsb pdb:5WKF|rcsb pdb:5WKG|rcsb pdb:5WKH|rcsb pdb:5WKI|rcsb pdb:5WL1|rcsb pdb:5WMN|rcsb pdb:5WMO|rcsb pdb:5WMP|rcsb pdb:5WMQ|rcsb pdb:5WMR|rcsb pdb:5WSH|rcsb pdb:5WWI|rcsb pdb:5WWJ|rcsb pdb:5WWU|rcsb pdb:5WXC|rcsb pdb:5WXD|rcsb pdb:5XOS|rcsb pdb:5XOT|rcsb pdb:5XOV|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6AEE|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|rcsb pdb:6AT5|rcsb pdb:6AT9|rcsb pdb:6AVF|rcsb pdb:6AVG|rcsb pdb:6BJ2|rcsb pdb:6BJ3|rcsb pdb:6BJ8|rcsb pdb:6BXP|rcsb pdb:6BXQ|rcsb pdb:6C09|rcsb pdb:6CUG|rcsb pdb:6D29|rcsb pdb:6C15|rcsb pdb:6C97|rcsb pdb:6D2B|rcsb pdb:6C98|rcsb pdb:6C99|rcsb pdb:6D2R|rcsb pdb:6D2T|rcsb pdb:6D64|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:6EI2|rcsb pdb:6ENY|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:6FGB|rcsb pdb:6G3J|rcsb pdb:6G3K|rcsb pdb:6GGM|rcsb pdb:6GH1|rcsb pdb:6GH4|rcsb pdb:6GHN|rcsb pdb:6GK3|rcsb pdb:6GL1|rcsb pdb:6ID4|rcsb pdb:6IEX|rcsb pdb:6ILM|rcsb pdb:6J1V|rcsb pdb:6J1W|rcsb pdb:6J29|rcsb pdb:6J2A|rcsb pdb:6J2E|rcsb pdb:6J2G|rcsb pdb:6J2H|rcsb pdb:6J2I|rcsb pdb:6J2J|rcsb pdb:6JOZ|rcsb pdb:6JP3|rcsb pdb:6JTN|rcsb pdb:6JTO|rcsb pdb:6JTP|rcsb pdb:6K60|rcsb pdb:6K7T|rcsb pdb:6LA6|rcsb pdb:6LA7|rcsb pdb:6M1B|rcsb pdb:6M24|rcsb pdb:6M2J|rcsb pdb:6M2K|rcsb pdb:6MPP|rcsb pdb:6MT3|rcsb pdb:6MT4|rcsb pdb:6MT5|rcsb pdb:6MT6|rcsb pdb:6MTL|rcsb pdb:6MTM|rcsb pdb:6MWR|rcsb pdb:6NCA|rcsb pdb:6NHA|rcsb pdb:6NPR|rcsb pdb:6NUX|rcsb pdb:6O4Y|rcsb pdb:6O4Z|rcsb pdb:6O51|rcsb pdb:6O53|rcsb pdb:6P2S|rcsb pdb:6P64|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6PBH|rcsb pdb:6PTB|rcsb pdb:6OPD|rcsb pdb:6P23|rcsb pdb:6P27|rcsb pdb:6P2C|rcsb pdb:6PTE|rcsb pdb:6P2F|rcsb pdb:6PUC|rcsb pdb:6PUD|rcsb pdb:6PUE|rcsb pdb:6PUF|rcsb pdb:6PUG|rcsb pdb:6PUH|rcsb pdb:6PUI|rcsb pdb:6PUJ|rcsb pdb:6PUK|rcsb pdb:6PUL|rcsb pdb:6PUM|rcsb pdb:6PVC|rcsb pdb:6PVD|rcsb pdb:6PYJ|rcsb pdb:6PYL|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|rcsb pdb:6Q3K|rcsb pdb:6Q3S|rcsb pdb:6QIO|rcsb pdb:6QIP|rcsb pdb:6R2L|rcsb pdb:6RP9|rcsb pdb:6RPA|rcsb pdb:6RPB|rcsb pdb:6RSY|rcsb pdb:6SS7|rcsb pdb:6SS8|rcsb pdb:6SS9|rcsb pdb:6SSA|rcsb pdb:6TDO|rcsb pdb:6TDP|rcsb pdb:6TDQ|rcsb pdb:6TDR|rcsb pdb:6TDS|rcsb pdb:6TMO|rcsb pdb:6TRN|rcsb pdb:6TRO|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6UJO|rcsb pdb:6UJQ|rcsb pdb:6UK2|rcsb pdb:6UK4|rcsb pdb:6ULI|rcsb pdb:6ULK|rcsb pdb:6ULN|rcsb pdb:6ULR|rcsb pdb:6UON|rcsb pdb:6UZ1|rcsb pdb:6UZM|rcsb pdb:6UZN|rcsb pdb:6UZO|rcsb pdb:6UZP|rcsb pdb:6UZQ|rcsb pdb:6UZS|rcsb pdb:6V2O|rcsb pdb:6V2P|rcsb pdb:6V2Q|rcsb pdb:6V3J|rcsb pdb:6V7Y|rcsb pdb:6V7Z|rcsb pdb:6V80|rcsb pdb:6VB0|rcsb pdb:6VB1|rcsb pdb:6VB2|rcsb pdb:6VB3|rcsb pdb:6VB5|rcsb pdb:6VB6|rcsb pdb:6VB7|rcsb pdb:6VIU|rcsb pdb:6VM7|rcsb pdb:6VM8|rcsb pdb:6VM9|rcsb pdb:6VB4|rcsb pdb:6VMA|rcsb pdb:6VMC|rcsb pdb:6VMX|rcsb pdb:6VPZ|rcsb pdb:6VQ2|rcsb pdb:6VQD|rcsb pdb:6VQE|rcsb pdb:6VQO|rcsb pdb:6VQY|rcsb pdb:6VQZ|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6W9U|rcsb pdb:6W9V|rcsb pdb:6WZY|rcsb pdb:6X00|rcsb pdb:6XQA|rcsb pdb:6XQP|rcsb pdb:6Y26|rcsb pdb:6Y27|rcsb pdb:6Y28|rcsb pdb:6Y29|rcsb pdb:6Y2A|rcsb pdb:6Y2B|rcsb pdb:6Z9V|rcsb pdb:6Z9W|rcsb pdb:6Z9X|rcsb pdb:7AFV|rcsb pdb:7ALO|rcsb pdb:7C9V|rcsb pdb:7JYU|rcsb pdb:7JYV|rcsb pdb:7JYW|rcsb pdb:7JYX|rcsb pdb:7K80|rcsb pdb:7K81|rcsb pdb:7KGO|rcsb pdb:7KGP|rcsb pdb:7KGQ|rcsb pdb:7KGR|rcsb pdb:7KGS|rcsb pdb:7KGT|rcsb pdb:7KOZ|rcsb pdb:7KP0|rcsb pdb:7KP1|rcsb pdb:7LFZ|rcsb pdb:7LG0|rcsb pdb:7LG2|rcsb pdb:7LG3|rcsb pdb:7LGD|rcsb pdb:7LGT|rcsb pdb:7M8S|rcsb pdb:7M8T|rcsb pdb:7M8U|rcsb pdb:7MKB|rcsb pdb:7NUI|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|reactome:R-HSA-198933|reactome:R-HSA-2172127|reactome:R-HSA-2424491|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-9637628|reactome:R-HSA-977225|reactome:R-HSA-983170|ensembl:ENSG00000166710(gene)|ensembl:ENSG00000273686(gene)|ensembl:ENST00000559916(transcript)|ensembl:ENST00000561424(transcript)|ensembl:ENST00000617605(transcript)|ensembl:ENST00000631573(transcript)|ensembl:ENST00000631728(transcript)|ensembl:ENST00000648006(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002481"(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0002237"(response to molecule of bacterial origin)|go:"GO:0005925"(focal adhesion)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007611"(learning or memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031905"(early endosome lumen)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042493"|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045087"(innate immune response)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071283"("cellular response to iron(III) ion")|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1904434"(positive regulation of ferrous iron binding)|go:"GO:1904437"(positive regulation of transferrin receptor binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000774"(positive regulation of cellular senescence)|go:"GO:2000978"(negative regulation of forebrain neuron differentiation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015707(Beta-2-Microglobulin)|interpro:IPR036179|mint:P61769|rcsb pdb:1A1M|rcsb pdb:1A1N|rcsb pdb:1A1O|rcsb pdb:1A6Z|rcsb pdb:1A9B|rcsb pdb:1A9E|rcsb pdb:1AGB|rcsb pdb:1AGC|rcsb pdb:1AGD|rcsb pdb:1AGE|rcsb pdb:1AGF|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1C16|rcsb pdb:1CE6|rcsb pdb:1CG9|rcsb pdb:1DE4|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1E27|rcsb pdb:1E28|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1EFX|rcsb pdb:1EXU|rcsb pdb:1GZP|rcsb pdb:1GZQ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1HSA|rcsb pdb:1HSB|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1IM9|rcsb pdb:1JF1|rcsb pdb:1JGD|rcsb pdb:1JGE|rcsb pdb:1JHT|rcsb pdb:1JNJ|rcsb pdb:1K5N|rcsb pdb:1KPR|rcsb pdb:1KTL|rcsb pdb:1LDS|rcsb pdb:1LP9|rcsb pdb:1M05|rcsb pdb:1M6O|rcsb pdb:1MHE|rcsb pdb:1MI5|rcsb pdb:1N2R|rcsb pdb:1OF2|rcsb pdb:1OGA|rcsb pdb:1OGT|rcsb pdb:1ONQ|rcsb pdb:1P7Q|rcsb pdb:1PY4|rcsb pdb:1Q94|rcsb pdb:1QEW|rcsb pdb:1QLF|rcsb pdb:1QQD|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1T20|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1QVO|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1R3H|rcsb pdb:1S8D|rcsb pdb:1TMC|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UQS|rcsb pdb:1UR7|rcsb pdb:1UXS|rcsb pdb:1UXW|rcsb pdb:1VGK|rcsb pdb:1W0V|rcsb pdb:1W0W|rcsb pdb:1W72|rcsb pdb:1X7Q|rcsb pdb:1XH3|rcsb pdb:1XR8|rcsb pdb:1XR9|rcsb pdb:1XZ0|rcsb pdb:1YDP|rcsb pdb:1YPZ|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1SYS|rcsb pdb:1SYV|rcsb pdb:1ZHK|rcsb pdb:1T1W|rcsb pdb:1ZHL|rcsb pdb:1ZS8|rcsb pdb:1ZSD|rcsb pdb:1ZT4|rcsb pdb:1ZVS|rcsb pdb:2A83|rcsb pdb:2AK4|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2AXF|rcsb pdb:2AXG|rcsb pdb:2BCK|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BSR|rcsb pdb:2BSS|rcsb pdb:2BST|rcsb pdb:2BVO|rcsb pdb:1T1X|rcsb pdb:2BVP|rcsb pdb:2BVQ|rcsb pdb:1T1Y|rcsb pdb:2C7U|rcsb pdb:2CII|rcsb pdb:1T1Z|rcsb pdb:2CIK|rcsb pdb:2CLR|rcsb pdb:2D31|rcsb pdb:2D4D|rcsb pdb:2D4F|rcsb pdb:2DYP|rcsb pdb:2E8D|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2F74|rcsb pdb:2F8O|rcsb pdb:2FYY|rcsb pdb:2FZ3|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2H26|rcsb pdb:2H6P|rcsb pdb:2HJK|rcsb pdb:2HJL|rcsb pdb:2HLA|rcsb pdb:2HN7|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2NW3|rcsb pdb:2NX5|refseq:NP_004039.1|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2RFX|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VB5|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:2X89|rcsb pdb:2XKS|rcsb pdb:2XKU|rcsb pdb:2XPG|rcsb pdb:2YPK|rcsb pdb:2YPL|rcsb pdb:2YXF|rcsb pdb:2Z9T|rcsb pdb:3AM8|rcsb pdb:3B3I|rcsb pdb:3B6S|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3BO8|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BVN|rcsb pdb:3BW9|rcsb pdb:3BWA|rcsb pdb:3BXN|rcsb pdb:3BZE|rcsb pdb:3BZF|rcsb pdb:3C9N|rcsb pdb:3CDG|rcsb pdb:3CII|rcsb pdb:3CIQ|rcsb pdb:3CZF|rcsb pdb:3D18|rcsb pdb:3D25|rcsb pdb:3D2U|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3DBX|rcsb pdb:3DHJ|rcsb pdb:3DHM|rcsb pdb:3DTX|rcsb pdb:3DX6|rcsb pdb:3DX7|rcsb pdb:3DX8|rcsb pdb:3DXA|rcsb pdb:3EKC|rcsb pdb:3FFC|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HCV|rcsb pdb:3HG1|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3HUJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3I6L|rcsb pdb:3IB4|rcsb pdb:3IXA|rcsb pdb:3JTS|rcsb pdb:3KLA|rcsb pdb:3KPL|rcsb pdb:3KPM|rcsb pdb:3KPN|rcsb pdb:3L3G|rcsb pdb:3L3I|rcsb pdb:3L3J|rcsb pdb:3L3K|rcsb pdb:3KPO|rcsb pdb:3LKN|rcsb pdb:3LKO|rcsb pdb:3LKP|rcsb pdb:3LKQ|rcsb pdb:3LKR|rcsb pdb:3LKS|rcsb pdb:3LN4|rcsb pdb:3LN5|rcsb pdb:3LOW|rcsb pdb:3LOZ|rcsb pdb:3LV3|rcsb pdb:3KPP|rcsb pdb:3KPQ|rcsb pdb:3KPR|rcsb pdb:3M17|rcsb pdb:3M1B|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3KPS|rcsb pdb:3KWW|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MV7|rcsb pdb:3KXF|rcsb pdb:3MV8|rcsb pdb:3MV9|rcsb pdb:3MYJ|rcsb pdb:3MYZ|rcsb pdb:3MZT|rcsb pdb:3KYN|rcsb pdb:3NA4|rcsb pdb:3NFN|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3OV6|rcsb pdb:3OX8|rcsb pdb:3OXR|rcsb pdb:3OXS|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDA|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QFD|rcsb pdb:3QFJ|rcsb pdb:3QZW|rcsb pdb:3REW|rcsb pdb:3KYO|rcsb pdb:3L3D|rcsb pdb:3RL1|rcsb pdb:3RL2|rcsb pdb:3RWJ|rcsb pdb:3S6C|rcsb pdb:3SDX|rcsb pdb:3SJV|rcsb pdb:3SKM|rcsb pdb:3SKO|rcsb pdb:3SPV|rcsb pdb:3TID|rcsb pdb:3TIE|rcsb pdb:3TLR|rcsb pdb:3TM6|rcsb pdb:3TO2|rcsb pdb:3TZV|rcsb pdb:3U0P|rcsb pdb:3UPR|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:3VCL|rcsb pdb:3VFM|rcsb pdb:3VFN|rcsb pdb:3VFO|rcsb pdb:3VFP|rcsb pdb:3VFR|rcsb pdb:3VFS|rcsb pdb:3VFT|rcsb pdb:3VFU|rcsb pdb:3VFV|rcsb pdb:3VFW|rcsb pdb:3VH8|rcsb pdb:3VRI|rcsb pdb:3VRJ|rcsb pdb:3VWJ|rcsb pdb:3VWK|rcsb pdb:3VXM|rcsb pdb:3VXN|rcsb pdb:3VXO|rcsb pdb:3VXP|rcsb pdb:3VXR|rcsb pdb:3VXS|rcsb pdb:3VXU|rcsb pdb:3W0W|rcsb pdb:3W39|rcsb pdb:3WL9|rcsb pdb:3WLB|rcsb pdb:3WUW|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:3X13|rcsb pdb:3X14|rcsb pdb:4E0K|rcsb pdb:4E0L|rcsb pdb:4E5X|rcsb pdb:4EN3|rcsb pdb:4EUP|rcsb pdb:4F7M|rcsb pdb:4F7P|rcsb pdb:4F7T|rcsb pdb:4FTV|rcsb pdb:4FXL|rcsb pdb:4G8G|rcsb pdb:4G8I|rcsb pdb:4G9D|rcsb pdb:4G9F|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4GUP|rcsb pdb:4HKJ|rcsb pdb:4HWZ|rcsb pdb:4HX1|rcsb pdb:4I48|rcsb pdb:4I4W|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|rcsb pdb:4JQV|rcsb pdb:3T8X|rcsb pdb:4JQX|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4K71|rcsb pdb:4K7F|rcsb pdb:4KDT|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:4L4T|rcsb pdb:4L4V|rcsb pdb:4LCW|rcsb pdb:4L3E|rcsb pdb:4LCY|rcsb pdb:4LHU|rcsb pdb:4LNR|rcsb pdb:4M8V|rcsb pdb:4MJ5|rcsb pdb:4MJ6|rcsb pdb:4MJI|rcsb pdb:4MNQ|rcsb pdb:4N0F|rcsb pdb:4N0U|rcsb pdb:4N8V|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4NQV|rcsb pdb:4NQX|rcsb pdb:4NT6|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4ONO|rcsb pdb:4PJ5|rcsb pdb:4PJ7|rcsb pdb:4PJ8|rcsb pdb:4PJ9|rcsb pdb:4PJA|rcsb pdb:4PJB|rcsb pdb:4PJC|rcsb pdb:4PJD|rcsb pdb:4PJE|rcsb pdb:4PJF|rcsb pdb:4PJG|rcsb pdb:4PJH|rcsb pdb:4PJI|rcsb pdb:4PJX|rcsb pdb:4PR5|rcsb pdb:4PRA|rcsb pdb:4PRB|rcsb pdb:4PRD|rcsb pdb:4PRE|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRN|rcsb pdb:4PRP|rcsb pdb:4QOK|rcsb pdb:4QRP|rcsb pdb:4QRQ|rcsb pdb:4QRR|rcsb pdb:4QRS|rcsb pdb:4QRT|rcsb pdb:4QRU|rcsb pdb:4R9H|rcsb pdb:4RA3|rcsb pdb:4RAH|rcsb pdb:4RMQ|rcsb pdb:4RMR|rcsb pdb:4RMS|rcsb pdb:4RMT|rcsb pdb:4RMU|rcsb pdb:4RMV|rcsb pdb:4RMW|rcsb pdb:4U1H|rcsb pdb:4U1I|rcsb pdb:4U1J|rcsb pdb:4U1K|rcsb pdb:4U1L|rcsb pdb:4U1M|rcsb pdb:4U1N|rcsb pdb:4U1S|rcsb pdb:4U6X|rcsb pdb:4U6Y|rcsb pdb:4UQ2|rcsb pdb:4UQ3|rcsb pdb:4WC8|rcsb pdb:4WDI|rcsb pdb:4WJ5|rcsb pdb:4WO4|rcsb pdb:4WU5|rcsb pdb:4WU7|rcsb pdb:4WUU|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4X0S|rcsb pdb:4X6C|rcsb pdb:4X6D|rcsb pdb:4X6E|rcsb pdb:4X6F|rcsb pdb:4Z76|rcsb pdb:4Z77|rcsb pdb:4Z78|rcsb pdb:5B38|rcsb pdb:5B39|rcsb pdb:4XXC|rcsb pdb:5BJT|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:5BXF|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5C9J|rcsb pdb:5CFH|rcsb pdb:5CKA|rcsb pdb:5CKG|rcsb pdb:5CS7|rcsb pdb:5CSB|rcsb pdb:5CSG|rcsb pdb:5D2L|rcsb pdb:5D2N|rcsb pdb:5D5M|rcsb pdb:5D7I|rcsb pdb:5D7J|rcsb pdb:5D7L|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5DEF|rcsb pdb:5DEG|rcsb pdb:5E00|rcsb pdb:5E6I|rcsb pdb:5E9D|rcsb pdb:5ENW|rcsb pdb:5EO0|rcsb pdb:5EO1|rcsb pdb:5EOT|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:5EUO|rcsb pdb:5F1I|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5GR7|rcsb pdb:5GRD|rcsb pdb:5GRG|rcsb pdb:5GSB|rcsb pdb:5GSD|rcsb pdb:5GSR|rcsb pdb:5GSV|rcsb pdb:5GSX|rcsb pdb:5HGA|rcsb pdb:5HGB|rcsb pdb:5HGD|rcsb pdb:5HGH|rcsb pdb:5HHM|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|dip:DIP-6055N - - - - figure legend:5C|comment:"KIR2DS1(+) KIR2DL1(−) NK cell clones"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/06/22 2019/10/18 rogid:P08CZT3zl5vRrh+ELuLhkCM7jR89606 rogid:3rs+twN73HOyUBaE1d4QZw6SxHk-2 rigid:JCZV0L60O3Ng8D2U9bfWzL2SnuI false sufficient binding region:?-? red fluorescent protein tag:?-?|sufficient binding region:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)