#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P38881	uniprotkb:P39968	intact:EBI-24885|uniprotkb:D3DLE3|ensemblfungi:YHR195W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:nvj1_yeast(display_long)|uniprotkb:VAB36(gene name synonym)|uniprotkb:NVJ1(gene name)|psi-mi:NVJ1(display_short)|uniprotkb:YHR195W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585039|wwpdb:5xjg|imex:IM-26254-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001238|refseq:NP_012065.3|dip:DIP-4215N|ensemblfungi:YHR195W(gene)|ensemblfungi:YHR195W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|rcsb pdb:5H2C|rcsb pdb:5XJG	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	-	crc64:B2E75774B47E5933	figure legend:Supp Table 1|3d-r-factors:Rworking 0.19 Rfree 0.222|3d-resolution:2.4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/02	2017/11/03	rogid:FuCJkSqjcRLYFSo6+HYXDqdHu4M559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:wJ5SIqopCPVBVv5NMSgbjkosS4c	false	sufficient binding region:229-321	sufficient binding region:10-515	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38881	uniprotkb:P39968	intact:EBI-24885|uniprotkb:D3DLE3|ensemblfungi:YHR195W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:nvj1_yeast(display_long)|uniprotkb:VAB36(gene name synonym)|uniprotkb:NVJ1(gene name)|psi-mi:NVJ1(display_short)|uniprotkb:YHR195W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585436|imex:IM-26254-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001238|refseq:NP_012065.3|dip:DIP-4215N|ensemblfungi:YHR195W(gene)|ensemblfungi:YHR195W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|rcsb pdb:5H2C|rcsb pdb:5XJG	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	-	crc64:B2E75774B47E5933	figure legend:Fig. 1B, 6E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/02	2017/11/03	rogid:FuCJkSqjcRLYFSo6+HYXDqdHu4M559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:wJ5SIqopCPVBVv5NMSgbjkosS4c	false	sufficient binding region:229-321	mutation disrupting interaction strength:55-55|sufficient binding region:34-515|mutation disrupting interaction strength:51-51	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38881	uniprotkb:P39968	intact:EBI-24885|uniprotkb:D3DLE3|ensemblfungi:YHR195W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:nvj1_yeast(display_long)|uniprotkb:VAB36(gene name synonym)|uniprotkb:NVJ1(gene name)|psi-mi:NVJ1(display_short)|uniprotkb:YHR195W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585445|imex:IM-26254-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001238|refseq:NP_012065.3|dip:DIP-4215N|ensemblfungi:YHR195W(gene)|ensemblfungi:YHR195W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|rcsb pdb:5H2C|rcsb pdb:5XJG	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	-	crc64:B2E75774B47E5933	figure legend:Fig. 6C|comment:The single VAC8 mutation ala51arg or leu55arg interfered with the dimer interface preventing the two NVJ1-VAC8 dimers from forming a tetramer as did deletion of residues 318-321 of Nvj1p.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/02	2017/11/03	rogid:FuCJkSqjcRLYFSo6+HYXDqdHu4M559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:wJ5SIqopCPVBVv5NMSgbjkosS4c	false	sufficient binding region:229-321	sufficient binding region:40-515	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38881	uniprotkb:P39968	intact:EBI-24885|uniprotkb:D3DLE3|ensemblfungi:YHR195W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:nvj1_yeast(display_long)|uniprotkb:VAB36(gene name synonym)|uniprotkb:NVJ1(gene name)|psi-mi:NVJ1(display_short)|uniprotkb:YHR195W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585309|imex:IM-26254-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001238|refseq:NP_012065.3|dip:DIP-4215N|ensemblfungi:YHR195W(gene)|ensemblfungi:YHR195W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|rcsb pdb:5H2C|rcsb pdb:5XJG	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	-	crc64:B2E75774B47E5933	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:0.71x10^-6(molar)	2017/11/02	2017/11/03	rogid:FuCJkSqjcRLYFSo6+HYXDqdHu4M559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:wJ5SIqopCPVBVv5NMSgbjkosS4c	false	sufficient binding region:229-321	sufficient binding region:10-515	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06628	uniprotkb:P39968	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585454|imex:IM-26254-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	crc64:45CD16F69B795E62	crc64:B2E75774B47E5933	figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:5.2x10^-7(molar)	2017/11/02	2017/11/03	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:yY0vHJXvWkGSth1lHO1P3oANMLs	false	sufficient binding region:567-738	sufficient binding region:10-515	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38881	uniprotkb:P39968	intact:EBI-24885|uniprotkb:D3DLE3|ensemblfungi:YHR195W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:nvj1_yeast(display_long)|uniprotkb:VAB36(gene name synonym)|uniprotkb:NVJ1(gene name)|psi-mi:NVJ1(display_short)|uniprotkb:YHR195W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585329|imex:IM-26254-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001238|refseq:NP_012065.3|dip:DIP-4215N|ensemblfungi:YHR195W(gene)|ensemblfungi:YHR195W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|rcsb pdb:5H2C|rcsb pdb:5XJG	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	-	crc64:B2E75774B47E5933	figure legend:Fig. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/02	2017/11/03	rogid:FuCJkSqjcRLYFSo6+HYXDqdHu4M559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:wJ5SIqopCPVBVv5NMSgbjkosS4c	false	sufficient binding region:229-321|mutation decreasing interaction strength:307-307|mutation disrupting interaction strength:319-319|mutation disrupting interaction strength:295-295,307-307,319-319|mutation with no effect:299-299|mutation with no effect:303-303|his tag:n-n|mutation decreasing interaction strength:295-295|mutation decreasing interaction strength:301-301	sufficient binding region:10-515|glutathione s tranferase tag:n-n|mutation disrupting interaction strength:276-276,317-317,359-359	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P25591	uniprotkb:P39968	intact:EBI-21800|uniprotkb:P25590|uniprotkb:D6VQV5|ensemblfungi:YCL063W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:vac17_yeast(display_long)|uniprotkb:YCL063W(locus name)|uniprotkb:YCL63W/YCL62W(orf name)|uniprotkb:VAC17(gene name)|psi-mi:VAC17(display_short)|uniprotkb:Vacuole-specific MYO2 receptor VAC17(gene name synonym)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585373|imex:IM-26254-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000568|refseq:NP_009870.1|mint:P25591|dip:DIP-2065N|ensemblfungi:YCL063W(gene)|ensemblfungi:YCL063W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|interpro:IPR035293	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	crc64:7F14A3A0BFE9571B	crc64:B2E75774B47E5933	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/02	2017/11/03	rogid:eOkU5SidNp4gs6B5BwPDReENlQA559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:mNGAdmkLz4nfXCkV1VdKv42OHbs	false	his tag:?-?|sufficient binding region:290-380	sufficient binding region:10-515|glutathione s tranferase tag:n-n|mutation with no effect:276-276,317-317,359-359	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q06628	uniprotkb:P39968	intact:EBI-36188|uniprotkb:D6W4I5|ensemblfungi:YPR185W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:atg13_yeast(display_long)|uniprotkb:ATG13(gene name)|psi-mi:ATG13(display_short)|uniprotkb:APG13(gene name synonym)|uniprotkb:YPR185W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585389|imex:IM-26254-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015511.1|sgd:S000006389|mint:Q06628|dip:DIP-1191N|ensemblfungi:YPR185W(gene)|ensemblfungi:YPR185W_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0071211"(protein targeting to vacuole involved in autophagy)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0120095"(vacuole-isolation membrane contact site)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|interpro:IPR018731|interpro:IPR036570|interpro:IPR040182|rcsb pdb:6KBM|rcsb pdb:6KBN|reactome:R-SCE-1632852|go:"GO:0019887"(protein kinase regulator activity)	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	crc64:45CD16F69B795E62	crc64:B2E75774B47E5933	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/02	2017/11/03	rogid:Op8+j2qoEeML+DW19641V5t7/js559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:yY0vHJXvWkGSth1lHO1P3oANMLs	false	his tag:?-?|sufficient binding region:567-738	sufficient binding region:10-515|glutathione s tranferase tag:?-?|mutation disrupting interaction strength:276-276,317-317,359-359	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q08001	uniprotkb:P39968	intact:EBI-30998|uniprotkb:D6VY73|ensemblfungi:YLR072W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:lam6_yeast(display_long)|uniprotkb:LAM6(gene name)|psi-mi:LAM6(display_short)|uniprotkb:LTC1(gene name synonym)|uniprotkb:Lipid transfer at contact site protein 1(gene name synonym)|uniprotkb:Lipid transfer protein anchored at membrane contact sites 1(gene name synonym)|uniprotkb:YLR072W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585538|imex:IM-26254-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013173.1|sgd:S000004062|dip:DIP-1861N|mint:Q08001|ensemblfungi:YLR072W(gene)|ensemblfungi:YLR072W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0120015"(sterol transfer activity)|go:"GO:1990816"(vacuole-mitochondrion membrane contact site)|interpro:IPR004182(GRAM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031968|rcsb pdb:5YQR	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	crc64:FACE2F16326B36F6	crc64:B2E75774B47E5933	figure legend:Supp Fig. 5B, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/02	2017/11/03	rogid:eJvCk1ECj5WUqoZQ5b/Jf1wKrZM559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:ehsWhCzOy4+M9tjp3VZ1SqFlhBs	false	his tag:n-n|sufficient binding region:400-628	sufficient binding region:10-515|glutathione s tranferase tag:n-n|mutation with no effect:276-276,317-317,359-359	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q08921	uniprotkb:P39968	intact:EBI-37395|uniprotkb:D6W3I8|ensemblfungi:YPL180W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:tco89_yeast(display_long)|uniprotkb:YPL180W(locus name)|uniprotkb:TCO89(gene name)|psi-mi:TCO89(display_short)|uniprotkb:89 kDa TOR complex 1 protein(gene name synonym)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0096"(pull down)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585554|imex:IM-26254-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015145.1|sgd:S000006101|mint:Q08921|dip:DIP-5347N|ensemblfungi:YPL180W(gene)|ensemblfungi:YPL180W_mRNA(transcript)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0009651"(response to salt stress)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|interpro:IPR018857	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	-	crc64:B2E75774B47E5933	figure legend:Supp Fig. 5B, 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/02	2017/11/03	rogid:e5XaDahzdAGS+ynPYEbLZrSPFPE559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:zHaxJkvvP4v12s0F1bEy/574KbA	false	his tag:n-n|sufficient binding region:401-600	sufficient binding region:10-515|glutathione s tranferase tag:n-n|mutation with no effect:276-276,317-317,359-359	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P38881	uniprotkb:P39968	intact:EBI-24885|uniprotkb:D3DLE3|ensemblfungi:YHR195W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:nvj1_yeast(display_long)|uniprotkb:VAB36(gene name synonym)|uniprotkb:NVJ1(gene name)|psi-mi:NVJ1(display_short)|uniprotkb:YHR195W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585257|imex:IM-26254-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001238|refseq:NP_012065.3|dip:DIP-4215N|ensemblfungi:YHR195W(gene)|ensemblfungi:YHR195W_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|rcsb pdb:5H2C|rcsb pdb:5XJG	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	-	crc64:B2E75774B47E5933	figure legend:Fig. 6D|comment:The single VAC8 mutation ala51arg or leu55arg interfered with the dimer interface preventing the two NVJ1-VAC8 dimers from forming a tetramer, as did deletion of residues 318-321 of Nvj1p.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/11/02	2017/11/03	rogid:FuCJkSqjcRLYFSo6+HYXDqdHu4M559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:wJ5SIqopCPVBVv5NMSgbjkosS4c	false	sufficient binding region:229-321	sufficient binding region:40-515	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39968	uniprotkb:P39968	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585521|imex:IM-26254-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	crc64:B2E75774B47E5933	crc64:B2E75774B47E5933	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/11/02	2017/11/03	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:dSbc4wqhkxqhf6EBodNyB5jDSKo	false	myc tag:?-?	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P39968	uniprotkb:P39968	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	intact:EBI-20212|uniprotkb:D3DLN6|uniprotkb:Q549T0|ensemblfungi:YEL013W	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:vac8_yeast(display_long)|uniprotkb:VAC8(gene name)|psi-mi:VAC8(display_short)|uniprotkb:YEB3(gene name synonym)|uniprotkb:YEL013W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Jeong et al. (2017)	pubmed:28533415|imex:IM-26254	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-16585530|imex:IM-26254-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	sgd:S000000739|refseq:NP_010903.3|mint:P39968|ensemblfungi:YEL013W(gene)|ensemblfungi:YEL013W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000425"(pexophagy)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0034517"(ribophagy)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045121"(membrane raft)|go:"GO:0071255"(Cvt vesicle assembly)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0071562"(nucleus-vacuole junction assembly)|go:"GO:0071563"(Myo2p-Vac17p-Vac8p transport complex)|go:"GO:1903044"(protein localization to membrane raft)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:5XJG|rcsb pdb:6KBM|rcsb pdb:6KBN|dip:DIP-5121N	-	crc64:B2E75774B47E5933	crc64:B2E75774B47E5933	figure legend:Fig. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2017/11/02	2017/11/03	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rogid:vxnzgu1OVqdfbmAB+Z6s9UbZSM0559292	rigid:dSbc4wqhkxqhf6EBodNyB5jDSKo	false	myc tag:?-?	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)