#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5U5X0	uniprotkb:P47985	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943120|imex:IM-25655-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:1A|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:Q9H1K1	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943120|imex:IM-25655-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:1A|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:P38646	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943120|imex:IM-25655-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:1A|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:Q8IWL3	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943120|imex:IM-25655-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:1A|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q9H1K1	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943134|imex:IM-25655-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:1B|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:P38646	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943134|imex:IM-25655-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:1B|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q8IWL3	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943134|imex:IM-25655-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:1B|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q5U5X0	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943134|imex:IM-25655-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:1B|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:O75251	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945360|imex:IM-25655-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3C|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606	rigid:BXBNT7/8EcyV2bvh/eefSqgT0f4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P19404	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945360|imex:IM-25655-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3C|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606	rigid:BXBNT7/8EcyV2bvh/eefSqgT0f4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P49821	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945360|imex:IM-25655-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3C|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606	rigid:BXBNT7/8EcyV2bvh/eefSqgT0f4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:O00217	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945360|imex:IM-25655-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3C|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606	rigid:BXBNT7/8EcyV2bvh/eefSqgT0f4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P28331	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945360|imex:IM-25655-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3C|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	rigid:BXBNT7/8EcyV2bvh/eefSqgT0f4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:Q9H1K1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945360|imex:IM-25655-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3C|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:BXBNT7/8EcyV2bvh/eefSqgT0f4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P38646	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945360|imex:IM-25655-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3C|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:BXBNT7/8EcyV2bvh/eefSqgT0f4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:Q562F6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-989213|ensembl:ENSP00000350447|uniprotkb:Q53RR9|uniprotkb:Q53T20|uniprotkb:Q86XY4|uniprotkb:Q8IWK2|uniprotkb:Q8IZK1|uniprotkb:Q8N1Q5|uniprotkb:Q96LQ3|intact:EBI-2559582	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sgo2_human(display_long)|uniprotkb:SGO2(gene name)|psi-mi:SGO2(display_short)|uniprotkb:Shugoshin-2(gene name synonym)|uniprotkb:Shugoshin-like 2(gene name synonym)|uniprotkb:Tripin(gene name synonym)|uniprotkb:SGOL2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000163535(gene)|ensembl:ENST00000357799(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0030892"(mitotic cohesin complex)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR026706|interpro:IPR038889|mint:Q562F6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:XP_011509036.1|refseq:NP_001153518.1|refseq:NP_689737.4|refseq:XP_005246402.1|dip:DIP-36615N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:lj8jTnNLhIEEqgqjvOrIJIS57yc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:A2RRP1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2267264|uniprotkb:O95790|uniprotkb:Q2VPJ7|uniprotkb:Q86V39|uniprotkb:Q8NFY8|uniprotkb:Q9Y3W5|uniprotkb:Q53TK6|intact:EBI-2561349|ensembl:ENSP00000281513	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nbas_human(display_long)|uniprotkb:NBAS(gene name)|psi-mi:NBAS(display_short)|uniprotkb:NAG(gene name synonym)|uniprotkb:Neuroblastoma-amplified gene protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056993.2|dip:DIP-56726N|ensembl:ENSG00000151779(gene)|ensembl:ENST00000281513(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR013244(Secretory pathway Sec39)|interpro:IPR029145|reactome:R-HSA-6811434	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:sxaeSd5hYMpu41GQ+C6X8hMeqjM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14545	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1396921|uniprotkb:B4DI89|uniprotkb:A8K5L6|intact:EBI-28969419|ensembl:ENSP00000257604|ensembl:ENSP00000396526	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:trad1_human(display_long)|uniprotkb:TRAFD1(gene name)|psi-mi:TRAFD1(display_short)|uniprotkb:FLN29(gene name synonym)|uniprotkb:Protein FLN29(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000257604|ensembl:ENSP00000396526|ensembl:ENST00000552890|ensembl:ENSP00000447340|refseq:NP_001137378.1|refseq:NP_006691.1|ensembl:ENSG00000135148(gene)|ensembl:ENST00000257604(transcript)|ensembl:ENST00000412615(transcript)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:2D9K	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:hDY19qxNvWdsjDOoUEpuYfe0cdA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q969M3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2124787|uniprotkb:Q4VSN6|uniprotkb:Q53EX4|uniprotkb:Q8NHE5|uniprotkb:Q9H338|uniprotkb:Q9H3U4|uniprotkb:D3DQF5|ensembl:ENSP00000274496|ensembl:ENSP00000397704	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:yipf5_human(display_long)|uniprotkb:YIPF5(gene name)|psi-mi:YIPF5(display_short)|uniprotkb:FINGER5(gene name synonym)|uniprotkb:YIP1A(gene name synonym)|uniprotkb:YIP1 family member 5(gene name synonym)|uniprotkb:YPT-interacting protein 1 A(gene name synonym)|uniprotkb:Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 5(gene name synonym)|uniprotkb:PP12723(orf name)|uniprotkb:SB140(orf name)|uniprotkb:UNQ3123/PRO10275(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001020118.1|refseq:NP_110426.4|refseq:NP_001258661.1|ensembl:ENST00000274496(transcript)|ensembl:ENST00000448443(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:0070971"(endoplasmic reticulum exit site)|mint:Q969M3|ensembl:ENSG00000145817(gene)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:tNd/CdASqK/08G9O9h3nivCTzKw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q08AM6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2107455|uniprotkb:Q13174|uniprotkb:Q6IA12|uniprotkb:Q7L4Y1|uniprotkb:Q9BW96|uniprotkb:Q9H6V6|uniprotkb:B3KPJ5|uniprotkb:B3KSM8|ensembl:ENSP00000261776	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:vac14_human(display_long)|uniprotkb:Tax1-binding protein 2(gene name synonym)|uniprotkb:VAC14(gene name)|psi-mi:VAC14(display_short)|uniprotkb:TAX1BP2(gene name synonym)|uniprotkb:TRX(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060522.3|ensembl:ENSG00000103043(gene)|ensembl:ENST00000261776(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000306"(extrinsic component of vacuolar membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070772"(PAS complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021841|interpro:IPR026825|mint:Q08AM6|rcsb pdb:7K1Y|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:S9syIZ/DKHNbOM0Nw9oZP5F+AvA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9C0C2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2104458|uniprotkb:Q6PJ35|uniprotkb:Q6ZV74|uniprotkb:A7E2F8|intact:EBI-28975617|ensembl:ENSP00000350990|ensembl:ENSP00000437271	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tb182_human(display_long)|uniprotkb:TNKS1BP1(gene name)|psi-mi:TNKS1BP1(display_short)|uniprotkb:KIAA1741(gene name synonym)|uniprotkb:TAB182(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_006718788.1|ensembl:ENSP00000350990|ensembl:ENSP00000437271|refseq:NP_203754.2|ensembl:ENSG00000149115(gene)|ensembl:ENST00000358252(transcript)|ensembl:ENST00000532437(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR032764|interpro:IPR040006|reactome:R-HSA-429947|reactome:R-HSA-6804115	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:pOIaK7wn7iYvUHbSA0kUZlIgtgw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z434	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-995373|uniprotkb:Q3I0Y2|uniprotkb:Q5T7I6|uniprotkb:Q86VY7|uniprotkb:Q9H1H3|uniprotkb:Q9H4Y1|uniprotkb:Q9H8D3|uniprotkb:Q9ULE9|uniprotkb:Q2HWT5|ensembl:ENSP00000401980|uniprotkb:M1P2Z0|uniprotkb:A8K6X0|uniprotkb:F5H6C8|uniprotkb:B2BD33|uniprotkb:B2BD34	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mavs_human(display_long)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001193420.1|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071660"(positive regulation of IP-10 production)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR011029(DEATH-like)|interpro:IPR026148|interpro:IPR031964|interpro:IPR042144|mint:Q7Z434|rcsb pdb:2MS7|rcsb pdb:2MS8|rcsb pdb:2VGQ|rcsb pdb:3J6C|rcsb pdb:3J6J|rcsb pdb:3RC5|rcsb pdb:4P4H|rcsb pdb:4Z8M|rcsb pdb:5JEK|reactome:R-HSA-168928|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-5689896|refseq:NP_065797.2|dip:DIP-35445N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H2V7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1386527|uniprotkb:Q9BRN5|uniprotkb:Q6P182|uniprotkb:Q71RB5|uniprotkb:Q7L541|uniprotkb:Q86VU7|uniprotkb:Q8TCS5|uniprotkb:B5MDM9|uniprotkb:Q8N953|intact:EBI-28986516|ensembl:ENSP00000309945	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:spns1_human(display_long)|uniprotkb:Spinster-like protein 1(gene name synonym)|uniprotkb:HSpin1(gene name synonym)|uniprotkb:PP20300(orf name)|uniprotkb:SPNS1(gene name)|psi-mi:SPNS1(display_short)|uniprotkb:SPIN1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001135920.1|refseq:NP_001135921.1|refseq:NP_001135922.1|refseq:NP_001135923.1|refseq:NP_114427.1|ensembl:ENSP00000309945|ensembl:ENST00000323081|ensembl:ENSP00000318228|ensembl:ENST00000334536|ensembl:ENSP00000335494|ensembl:ENST00000352260|ensembl:ENSP00000306050|ensembl:ENSG00000169682(gene)|ensembl:ENST00000311008(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|interpro:IPR044770|mint:Q9H2V7	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ktf9VuiQy4rOhDVvg5J+wVSshec9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8IXI2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1396430|uniprotkb:A4FVB6|uniprotkb:Q6NUR3|uniprotkb:Q6P9F8|uniprotkb:Q6PJG1|uniprotkb:Q6YMW8|uniprotkb:Q86UB0|uniprotkb:Q8IW28|uniprotkb:Q8IXJ7|uniprotkb:Q9H067|uniprotkb:Q9H9N8|uniprotkb:Q9NUZ2|uniprotkb:A6NFV0|uniprotkb:B4DG48|uniprotkb:J9JIH9|ensembl:ENSP00000334724	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:miro1_human(display_long)|uniprotkb:Ras homolog gene family member T1(gene name synonym)|uniprotkb:Rac-GTP-binding protein-like protein(gene name synonym)|uniprotkb:RHOT1(gene name)|psi-mi:RHOT1(display_short)|uniprotkb:ARHT1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001028738.1|refseq:NP_001028740.1|refseq:NP_060777.3|refseq:NP_001028739.2|refseq:NP_001275683.1|refseq:NP_001275684.1|refseq:NP_001275687.1|dip:DIP-39114N|ensembl:ENSG00000126858(gene)|ensembl:ENST00000333942(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034640"(establishment of mitochondrion localization by microtubule attachment)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|interpro:IPR029506|mint:Q8IXI2|rcsb pdb:5KSO|rcsb pdb:5KSP|rcsb pdb:5KSY|rcsb pdb:5KSZ|rcsb pdb:5KTY|rcsb pdb:5KU1|rcsb pdb:6D71|reactome:R-HSA-5689880|reactome:R-HSA-9013425	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:gA6A8bgSwshvMwCO0cG66h+wwIY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8IXI1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1396563|uniprotkb:Q8NF53|uniprotkb:Q96C13|uniprotkb:Q96S17|uniprotkb:Q9BT60|uniprotkb:Q9H7M8|uniprotkb:A2IDC2|ensembl:ENSP00000321971	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:miro2_human(display_long)|uniprotkb:RHOT2(gene name)|psi-mi:RHOT2(display_short)|uniprotkb:ARHT2(gene name synonym)|uniprotkb:C16orf39(gene name synonym)|uniprotkb:Ras homolog gene family member T2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_620124.1|ensembl:ENSG00000140983(gene)|ensembl:ENST00000315082(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|interpro:IPR001806(Ras GTPase)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR011992(EF-Hand type)|interpro:IPR013566(EF hand associated, type-1)|interpro:IPR013567(EF hand associated, type-2)|interpro:IPR018247|interpro:IPR020860|interpro:IPR021181|interpro:IPR027417|mint:Q8IXI1|rcsb pdb:5KUT|reactome:R-HSA-9013419	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:E+WoN8aoND+U/YkLBUTecrNbDXg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P35250	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UPQ3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7159788|ensembl:ENSP00000307634|intact:MINT-6783717|uniprotkb:Q6P9D7|uniprotkb:B2RTX7|uniprotkb:Q541S5|uniprotkb:Q9NV93	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:agap1_human(display_long)|uniprotkb:KIAA1099(gene name synonym)|uniprotkb:AGAP1(gene name)|psi-mi:AGAP1(display_short)|uniprotkb:CENTG2(gene name synonym)|uniprotkb:Centaurin-gamma-2(gene name synonym)|uniprotkb:GTP-binding and GTPase-activating protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000157985(gene)|ensembl:ENST00000304032(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0015031"(protein transport)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|rcsb pdb:7EB6|refseq:NP_001231817.1|refseq:NP_055729.2|refseq:NP_001032208.1	go:"GO:0043229"(intracellular organelle)	-	function:"GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system"|comment:mint|comment:homomint	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:iVoZlA+NlH5VgJUpAAL0ZbRSiZE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H497	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11321815|uniprotkb:Q9H6E7|uniprotkb:Q9H495|uniprotkb:Q8WVA7|uniprotkb:B4DSY0|uniprotkb:Q8WWM2|uniprotkb:B7ZB65|uniprotkb:Q5M7Y7|ensembl:ENSP00000356599	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tor3a_human(display_long)|uniprotkb:TOR3A(gene name)|psi-mi:TOR3A(display_short)|uniprotkb:ADIR(gene name synonym)|uniprotkb:ATP-dependent interferon-responsive protein(gene name synonym)|uniprotkb:Torsin family 3 member A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_071766.2|ensembl:ENSG00000186283(gene)|ensembl:ENST00000367627(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR010448(Torsin)|interpro:IPR027417|interpro:IPR030552|dip:DIP-59333N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:OCIxqrq7OpzraBBKaCvbUPzQoKg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:A1YPR0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7954052|uniprotkb:O73453|intact:MINT-7944746|intact:EBI-28970803|ensembl:ENSP00000439781|ensembl:ENSP00000467877|ensembl:ENSP00000468254|ensembl:ENSP00000468782	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:zbt7c_human(display_long)|uniprotkb:ZNF857C(gene name synonym)|uniprotkb:Zinc finger protein 857C(gene name synonym)|uniprotkb:ZBTB7C(gene name)|psi-mi:ZBTB7C(display_short)|uniprotkb:APM1(gene name synonym)|uniprotkb:ZBTB36(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 36(gene name synonym)|uniprotkb:Affected by papillomavirus DNA integration in ME180 cells protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000439781|ensembl:ENSP00000468254|ensembl:ENSP00000468782|ensembl:ENSP00000467877|refseq:XP_011524172.1|refseq:XP_011524173.1|refseq:NP_001034449.1|refseq:XP_005258286.1|refseq:NP_001305770.1|refseq:XP_016881098.1|dip:DIP-61583N|ensembl:ENSG00000184828(gene)|ensembl:ENST00000535628(transcript)|ensembl:ENST00000586438(transcript)|ensembl:ENST00000588982(transcript)|ensembl:ENST00000590800(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1903025"(regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036236	go:"GO:0043229"(intracellular organelle)	-	comment:mint|comment:homomint	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:LV5hrk11gifPBLA+unNWP8Mk89U9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NHH1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7967634|intact:MINT-7970579|uniprotkb:F8W6M1|ensembl:ENSP00000321346|ensembl:ENSP00000362881	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ttl11_human(display_long)|uniprotkb:TTLL11(gene name)|psi-mi:TTLL11(display_short)|uniprotkb:C9orf20(gene name synonym)|uniprotkb:Tubulin--tyrosine ligase-like protein 11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001132914.1|refseq:NP_919228.2|ensembl:ENSG00000175764(gene)|ensembl:ENST00000321582(transcript)|ensembl:ENST00000373776(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0015631"(tubulin binding)|go:"GO:0018095"(protein polyglutamylation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051013"(microtubule severing)|go:"GO:0070740"(tubulin-glutamic acid ligase activity)|interpro:IPR004344(Tubulin-tyrosine ligase)|reactome:R-HSA-8955332	go:"GO:0043229"(intracellular organelle)	-	comment:mint	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:37h3oxdKZk268CHlem3X2ayQ96o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15118	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7016221|uniprotkb:B7Z937|uniprotkb:E9PD65|uniprotkb:Q308M4|ensembl:ENSP00000282077|ensembl:ENSP00000386985|uniprotkb:B2R6T1|intact:MINT-2881420|uniprotkb:D3DPD8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pdk1_human(display_long)|uniprotkb:PDK1(gene name)|psi-mi:PDK1(display_short)|uniprotkb:PDHK1(gene name synonym)|uniprotkb:Pyruvate dehydrogenase kinase isoform 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	dip:DIP-29497N|ensembl:ENSG00000152256(gene)|ensembl:ENST00000282077(transcript)|ensembl:ENST00000410055(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010510"(regulation of acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:Q15118|rcsb pdb:2Q8F|rcsb pdb:2Q8G|rcsb pdb:2Q8H|reactome:R-HSA-204174|reactome:R-HSA-5362517|refseq:NP_002601.1|refseq:NP_001265478.1	go:"GO:0043229"(intracellular organelle)	-	comment:mint|comment:homomint|function:Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bGVYvRnjKgE4fa6X5wY5SveeIUM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HD23	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6164303|ensembl:ENSP00000367637|uniprotkb:B4DQL2|uniprotkb:A8K4U3|uniprotkb:B3KNN2|uniprotkb:Q5T3Y1|uniprotkb:Q6NTG4|uniprotkb:Q96KF8|uniprotkb:Q9BVP1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mrs2_human(display_long)|uniprotkb:MRS2(gene name)|psi-mi:MRS2(display_short)|uniprotkb:HPT(gene name synonym)|uniprotkb:MRS2-like protein(gene name synonym)|uniprotkb:MRS2L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000124532(gene)|ensembl:ENST00000378386(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045016"(mitochondrial magnesium ion transmembrane transport)|go:"GO:0055085"(transmembrane transport)|interpro:IPR039204|reactome:R-HSA-5223345|refseq:NP_001273193.1|refseq:NP_001273194.1|refseq:NP_001273195.1|refseq:NP_065713.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qvKwgSW3lcwro4mQsW0ex2yN6IM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UPQ8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-8645574|ensembl:ENSP00000361667|uniprotkb:Q5SRE6|intact:MINT-4724096|intact:MINT-8163513	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dolk_human(display_long)|uniprotkb:KIAA1094(gene name synonym)|uniprotkb:UNQ2422/PRO4980(orf name)|uniprotkb:DOLK(gene name)|psi-mi:DOLK(display_short)|uniprotkb:TMEM15(gene name synonym)|uniprotkb:Transmembrane protein 15(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000175283(gene)|ensembl:ENST00000372586(transcript)|go:"GO:0004168"(dolichol kinase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043048"(dolichyl monophosphate biosynthetic process)|interpro:IPR026566|interpro:IPR032974|reactome:R-HSA-446199|reactome:R-HSA-4755583|refseq:NP_055723.1	go:"GO:0043229"(intracellular organelle)	-	function:"Defects in TMEM15 are the cause of congenital disorder of glycosylation type 1M (CDG1M) [MIM:610768]; also known as dolichol kinase deficiency. CDGs are a family of severe inherited diseases caused by a defect in glycoprotein biosynthesis. They are characterized by under-glycosylated serum glycoproteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. CDG1M is a very severe disorder with death occurring in early infancy"	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:oVMRd2DWTKCgO7cySF3k2IbBfn09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BVQ7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7950854|uniprotkb:Q9HA41|intact:MINT-4718214|uniprotkb:Q9H8W7|uniprotkb:C9JHR5|ensembl:ENSP00000305494	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:spa5l_human(display_long)|uniprotkb:SPATA5L1(gene name)|psi-mi:SPATA5L1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_076968.2|refseq:NP_001310569.1|ensembl:ENSG00000171763(gene)|ensembl:ENST00000305560(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR041569|mint:Q9BVQ7	go:"GO:0043229"(intracellular organelle)	-	comment:mint|comment:homomint	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8FTQdkGYS4xx3pmJDk9xNtPy3Ao9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9GZP9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	go:"GO:0043229"(intracellular organelle)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P61009	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6166040|ensembl:ENSP00000427463|uniprotkb:P12280|uniprotkb:Q9H0S7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:spcs3_human(display_long)|uniprotkb:SPCS3(gene name)|psi-mi:SPCS3(display_short)|uniprotkb:Microsomal signal peptidase 22/23 kDa subunit(gene name synonym)|uniprotkb:SPC22(gene name synonym)|uniprotkb:UNQ1841/PRO3567(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000129128(gene)|ensembl:ENST00000503362(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR007653(Signal peptidase 22 kDa subunit)|mint:P61009|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_068747.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:IJjfzKRjeZefoy2znnC4XC6wgOU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96E22	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6949352|ensembl:ENSP00000357480|uniprotkb:O00251|intact:MINT-3052208|uniprotkb:B2RWQ4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ngbr_human(display_long)|uniprotkb:NUS1(gene name)|psi-mi:NUS1(display_short)|uniprotkb:C6orf68(gene name synonym)|uniprotkb:NGBR(gene name synonym)|uniprotkb:Nuclear undecaprenyl pyrophosphate synthase 1 homolog(gene name synonym)|uniprotkb:Nogo-B receptor(gene name synonym)|uniprotkb:Cis-prenyltransferase subunit NgBR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000153989(gene)|ensembl:ENST00000368494(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019408"(dolichol biosynthetic process)|rcsb pdb:6W2L|rcsb pdb:6Z1N|reactome:R-HSA-446199|reactome:R-HSA-4755609|go:"GO:0030154"(cell differentiation)|go:"GO:0032383"(regulation of intracellular cholesterol transport)|go:"GO:0035268"(protein mannosylation)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR036424|interpro:IPR038887|refseq:NP_612468.1|dip:DIP-61225N	go:"GO:0043229"(intracellular organelle)	-	comment:mint|function:Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. Able to regulate vascular remodeling and angiogenesis. Its similarity with UPP synthetase proteins suggests that it may act as a scaffold for the binding of isoprenyl lipids and/or prenylated proteins|comment:homomint	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:htBbXzyI2bJDFvyuFFWIeAnF3sc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q2PZI1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6164516|ensembl:ENSP00000308695|uniprotkb:O94954|uniprotkb:Q4G151	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:d19l1_human(display_long)|uniprotkb:Protein dpy-19 homolog 1(gene name synonym)|uniprotkb:DPY19L1(gene name)|psi-mi:DPY19L1(display_short)|uniprotkb:Dpy-19-like protein 1(gene name synonym)|uniprotkb:GA0500(gene name synonym)|uniprotkb:KIAA0877(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000173852(gene)|ensembl:ENST00000310974(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|interpro:IPR018732|interpro:IPR030041|go:"GO:0000030"(mannosyltransferase activity)|refseq:NP_056098.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:JnDZiz7UFIUQvuIps5neyIQulsY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8WVC6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11319548|uniprotkb:Q9H5W1|uniprotkb:D3DX62|uniprotkb:D3DX60|uniprotkb:A8K3Z0|uniprotkb:Q9BR71|ensembl:ENSP00000308515|ensembl:ENSP00000341504|ensembl:ENSP00000413483|ensembl:ENSP00000467913|ensembl:ENSP00000478909|ensembl:ENSP00000498268	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dcakd_human(display_long)|uniprotkb:DCAKD(gene name)|psi-mi:DCAKD(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_016880591.1|refseq:XP_016880592.1|refseq:XP_016880593.1|refseq:NP_001122103.1|refseq:NP_001275583.1|refseq:NP_001275584.1|refseq:NP_079095.3|refseq:XP_005257745.1|refseq:XP_011523564.1|refseq:NP_001308255.1|ensembl:ENST00000651974(transcript)|go:"GO:0004140"(dephospho-CoA kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016020"(membrane)|interpro:IPR001977(Dephospho-CoA kinase)|interpro:IPR027417|mint:Q8WVC6|ensembl:ENSG00000172992(gene)|ensembl:ENST00000310604(transcript)|ensembl:ENST00000342350(transcript)|ensembl:ENST00000452796(transcript)|ensembl:ENST00000588499(transcript)|ensembl:ENST00000614054(transcript)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:b6jKOSLEjdHLqm69BmVHjW8R5G49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P07203	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7209024|uniprotkb:E9PAS1|ensembl:ENSP00000407375|uniprotkb:Q7Z5H1|uniprotkb:Q9BW12|intact:UNK-5370138	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gpx1_human(display_long)|uniprotkb:GPX1(gene name)|psi-mi:GPX1(display_short)|uniprotkb:Cellular glutathione peroxidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000572.2|ensembl:ENSG00000233276(gene)|ensembl:ENST00000419783(transcript)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001885"(endothelial cell development)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0009609"(response to symbiotic bacterium)|go:"GO:0009650"(UV protection)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042311"(vasodilation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060047"(heart contraction)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902905"(positive regulation of supramolecular fiber organization)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|mint:P07203|rcsb pdb:2F8A|reactome:R-HSA-2142688|reactome:R-HSA-2142712|reactome:R-HSA-2142770|reactome:R-HSA-3299685|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)	go:"GO:0043229"(intracellular organelle)	-	comment:mint|comment:homomint|function:Protects the hemoglobin in erythrocytes from oxidative breakdown	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:1/6I8LekGumy+rLlaLFqCbl1gV09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P53004	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7410441|intact:MINT-1212210|uniprotkb:Q96QL4|uniprotkb:A8K747|uniprotkb:Q9BRW8|uniprotkb:Q86UX0|uniprotkb:O95019|ensembl:ENSP00000265523|ensembl:ENSP00000385757	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:biea_human(display_long)|uniprotkb:BLVRA(gene name)|psi-mi:BLVRA(display_short)|uniprotkb:BLVR(gene name synonym)|uniprotkb:BVR(gene name synonym)|uniprotkb:Biliverdin-IX alpha-reductase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011513776.1|refseq:NP_001240752.1|refseq:NP_000703.2|refseq:XP_016868009.1|ensembl:ENSG00000106605(gene)|ensembl:ENST00000265523(transcript)|ensembl:ENST00000402924(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004074"("biliverdin reductase (NAD(P)+) activity")|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042167"(heme catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106276"(biliberdin reductase NAD+ activity)|go:"GO:0106277"("biliverdin reductase (NADP+) activity")|interpro:IPR000683(Oxidoreductase, N-terminal)|interpro:IPR015249(Biliverdin reductase, catalytic)|interpro:IPR017094(Biliverdin reductase A)|interpro:IPR036291|rcsb pdb:2H63|reactome:R-HSA-189483|reactome:R-HSA-9707564|dip:DIP-42180N	go:"GO:0043229"(intracellular organelle)	-	comment:mint|function:Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:gcpdPe6YxaYS3dRJ3JRAeEpJbtk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q4U2R6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7825372|ensembl:ENSP00000229238|uniprotkb:Q9P0N7|uniprotkb:Q9BQ36|uniprotkb:Q96Q57|intact:MINT-6775055	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rm51_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL51(gene name synonym)|uniprotkb:MRPL51(gene name)|psi-mi:MRPL51(display_short)|uniprotkb:MRP64(gene name synonym)|uniprotkb:bMRP-64(gene name synonym)|uniprotkb:CDA09(orf name)|uniprotkb:HSPC241(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000111639(gene)|ensembl:ENST00000229238(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR019373|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_057581.2	go:"GO:0043229"(intracellular organelle)	-	comment:mint	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Jmv8XkomwgJeeYC7B5An8nd12AE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P48651	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-8652106|uniprotkb:B4DE85|uniprotkb:E5RFC5|uniprotkb:Q9BUQ5|intact:MINT-8163942|ensembl:ENSP00000430548	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ptss1_human(display_long)|uniprotkb:PTDSS1(gene name)|psi-mi:PTDSS1(display_short)|uniprotkb:KIAA0024(gene name synonym)|uniprotkb:PSSA(gene name synonym)|uniprotkb:Serine-exchange enzyme I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001277154.1|refseq:NP_055569.1|ensembl:ENSG00000156471(gene)|ensembl:ENST00000517309(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0106245"(L-serine-phosphatidylethanolamine phosphatidyltransferase activity)|go:"GO:0106258"(L-serine-phosphatidylcholine phosphatidyltransferase activity)|interpro:IPR004277(Phosphatidyl serine synthase)|mint:P48651|reactome:R-HSA-1483101	go:"GO:0043229"(intracellular organelle)	-	comment:mint	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FDSRlCB+/84r8jXnvywHmzAqq9s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5SUL5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-8561769|uniprotkb:O77964|uniprotkb:Q9TP25|intact:MINT-4655826|uniprotkb:Q9TQP5|uniprotkb:O78171|uniprotkb:Q9MYA3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:1a01_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A*01(gene name synonym)|uniprotkb:HLA(gene name synonym)|uniprotkb:HLA-A*0101(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0016032"(viral process)|rcsb pdb:4NQV|rcsb pdb:4NQX|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|rcsb pdb:5BRZ|rcsb pdb:5BS0|rcsb pdb:6AT9|uniprotkb:P30443(see-also)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0050776"(regulation of immune response)|refseq:NP_001229687.1|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|go:"GO:0030670"(phagocytic vesicle membrane)|interpro:IPR011161(MHC class I-like antigen recognition)|go:"GO:0031901"(early endosome membrane)|go:"GO:0000139"(Golgi membrane)|rcsb pdb:3BO8|go:"GO:0016045"(detection of bacterium)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|rcsb pdb:1W72|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0046977"(TAP binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0016020"(membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0009986"(cell surface)|go:"GO:0030881"(beta-2-microglobulin binding)|ensembl:ENST00000431930|ensembl:ENST00000443552|ensembl:ENST00000549869|ensembl:ENST00000552193|ensembl:ENSG00000224320|ensembl:ENSG00000229215|ensembl:ENSP00000404678|ensembl:ENSP00000406366|ensembl:ENSP00000447614|ensembl:ENSP00000447635|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR036179|interpro:IPR037055|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0002419"(T cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019882"(antigen processing and presentation)	go:"GO:0043229"(intracellular organelle)	-	no-uniprot-update:This interactor won't be updated using Uniprot.|comment:mint|function:Involved in the presentation of foreign antigens to the immune system	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:uHpz+xHq7vqEm6W6UJHYpu/R3WM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NWW5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6165897|ensembl:ENSP00000249806|uniprotkb:B4DDH6|uniprotkb:A8K560|uniprotkb:Q6IAB1|uniprotkb:Q96SR0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cln6_human(display_long)|uniprotkb:CLN6(gene name)|psi-mi:CLN6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000128973(gene)|ensembl:ENST00000249806(transcript)|go:"GO:0001573"(ganglioside metabolic process)|go:"GO:0005730"(nucleolus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007601"(visual perception)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044265"(cellular macromolecule catabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0120146"(sulfatide binding)|interpro:IPR029255|refseq:NP_060352.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:oX9lqo/LjQbBWTpBj1voRRmnOO89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P78540	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-9056613|uniprotkb:B2R690|uniprotkb:Q6FHY8|ensembl:ENSP00000261783	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:argi2_human(display_long)|uniprotkb:ARG2(gene name)|psi-mi:ARG2(display_short)|uniprotkb:Kidney-type arginase(gene name synonym)|uniprotkb:Non-hepatic arginase(gene name synonym)|uniprotkb:Type II arginase(gene name synonym)|uniprotkb:Arginase II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001163.1|ensembl:ENSG00000081181(gene)|ensembl:ENST00000261783(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001657"(ureteric bud development)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002829"(negative regulation of type 2 immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032696"(negative regulation of interleukin-13 production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0045087"(innate immune response)|go:"GO:0071641"(negative regulation of macrophage inflammatory protein 1 alpha production)|go:"GO:0071644"("negative regulation of chemokine (C-C motif) ligand 4 production")|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:1903426"(regulation of reactive oxygen species biosynthetic process)|go:"GO:1905403"(negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|interpro:IPR020855|interpro:IPR023696|rcsb pdb:1PQ3|rcsb pdb:4HZE|rcsb pdb:4I06|rcsb pdb:4IE2|rcsb pdb:4IE3|rcsb pdb:4IXU|rcsb pdb:4IXV|rcsb pdb:6Q37|rcsb pdb:6Q39|rcsb pdb:6SS2|rcsb pdb:6SS4|rcsb pdb:6SS6|reactome:R-HSA-70635	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:AVVSVOCI1bPFUPMjojG4QSwFjIA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96EY8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-7825413|ensembl:ENSP00000445920|intact:UNK-5534451|uniprotkb:Q9BSH0|uniprotkb:C5HU05	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mmab_human(display_long)|uniprotkb:MMAB(gene name)|psi-mi:MMAB(display_short)|uniprotkb:Methylmalonic aciduria type B protein(gene name synonym)|uniprotkb:"Cob(II)alamin adenosyltransferase"(gene name synonym)|uniprotkb:"Cob(II)yrinic acid a,c-diamide adenosyltransferase"(gene name synonym)|uniprotkb:Cobinamide/cobalamin adenosyltransferase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000545712(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008817"("cob(I)yrinic acid a,c-diamide adenosyltransferase activity")|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0031419"(cobalamin binding)|interpro:IPR016030("Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like")|interpro:IPR029499|interpro:IPR036451|rcsb pdb:2IDX|rcsb pdb:6D5K|rcsb pdb:6D5X|reactome:R-HSA-196741|reactome:R-HSA-3359471|ensembl:ENSG00000139428(gene)|refseq:NP_443077.1	go:"GO:0043229"(intracellular organelle)	-	comment:mint|function:"Defects in MMAB are the cause of methylmalonic aciduria linked to the cblB complementation group (MMAB) [MIM:251110]; also known as methylmalonic aciduria type B or vitamin B12-responsive methylmalonicaciduria of cblB complementation type. MMAB is due to defective synthesis of adenosylcobalamin. Inheritance is autosomal recessive"	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:mCC0sM9ENytksAmo6ICWkWQHbZA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y6C9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6164522|ensembl:ENSP00000303222|ensembl:ENSP00000495027|uniprotkb:B2R7L8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mtch2_human(display_long)|uniprotkb:MTCH2(gene name)|psi-mi:MTCH2(display_short)|uniprotkb:MIMP(gene name synonym)|uniprotkb:Met-induced mitochondrial protein(gene name synonym)|uniprotkb:HSPC032(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	interpro:IPR018108|interpro:IPR023395|mint:Q9Y6C9|go:"GO:0070585"(protein localization to mitochondrion)|ensembl:ENSG00000109919(gene)|ensembl:ENSG00000285121(gene)|ensembl:ENST00000302503(transcript)|ensembl:ENST00000643223(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|refseq:NP_001304160.1|refseq:NP_001304161.1|refseq:NP_001304162.1|refseq:NP_055157.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Lbg7MBRn09cRzoYOiSt4g4FjsjA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NRK6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6164528|ensembl:ENSP00000355637|uniprotkb:Q13040|uniprotkb:Q6P1Q8|uniprotkb:Q9H3V0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:abcba_human(display_long)|uniprotkb:ABC-mitochondrial erythroid protein(gene name synonym)|uniprotkb:ABCB10(gene name)|psi-mi:ABCB10(display_short)|uniprotkb:ATP-binding cassette transporter 10(gene name synonym)|uniprotkb:Mitochondrial ATP-binding cassette 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000135776(gene)|ensembl:ENST00000344517(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048821"(erythrocyte development)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|go:"GO:0006783"(heme biosynthetic process)|interpro:IPR036640|interpro:IPR039421|rcsb pdb:3ZDQ|rcsb pdb:4AYT|rcsb pdb:4AYW|rcsb pdb:4AYX|reactome:R-HSA-1369007|interpro:IPR030260|refseq:NP_036221.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:XJOAh9Mv+ivD/9GzGjjkmvyvf9g9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13546	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|ensembl:ENSG00000137275(gene)|ensembl:ENST00000259808(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0010008"(endosome membrane)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043235"(receptor complex)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070513"(death domain binding)|go:"GO:0070926"("regulation of ATP:ADP antiporter activity")|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097342"(ripoptosome)|go:"GO:0097343"(ripoptosome assembly)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR025735|interpro:IPR037934|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9693928|go:"GO:0070266"(necroptotic process)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P27708	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q14204	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-356015|intact:EBI-4399546|uniprotkb:Q6DKQ7|uniprotkb:Q8WU28|uniprotkb:Q92814|uniprotkb:Q9Y4G5|uniprotkb:B0I1R0|intact:EBI-28969816|ensembl:ENSP00000348965	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dyhc1_human(display_long)|uniprotkb:DYNC1H1(gene name)|psi-mi:DYNC1H1(display_short)|uniprotkb:DNECL(gene name synonym)|uniprotkb:KIAA0325(gene name synonym)|uniprotkb:DNCH1(gene name synonym)|uniprotkb:DNCL(gene name synonym)|uniprotkb:DHC1(gene name synonym)|uniprotkb:DYHC(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001367.2|ensembl:ENSP00000348965|ensembl:ENSG00000197102(gene)|ensembl:ENST00000360184(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|mint:Q14204|rcsb pdb:2BOR|rcsb pdb:2BOT|rcsb pdb:5NUG|rcsb pdb:5OWO|rcsb pdb:6F1T|rcsb pdb:6F1U|rcsb pdb:6F1V|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|dip:DIP-37544N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:nI5RCxHByU3dxtLnPMPEjJlx1Fc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P42704	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N4P6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943456|ensembl:ENSP00000336661|uniprotkb:Q96M24	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lrc71_human(display_long)|uniprotkb:LRRC71(gene name)|psi-mi:LRRC71(display_short)|uniprotkb:C1orf92(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000160838(gene)|ensembl:ENST00000337428(transcript)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|refseq:NP_653303.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:YrKA4g1Vg/b7vFDmADGFJOXIyjI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UET6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1055987|uniprotkb:O75670|uniprotkb:B2RCJ0|ensembl:ENSP00000326948	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:trm7_human(display_long)|uniprotkb:FTSJ1(gene name)|psi-mi:FTSJ1(display_short)|uniprotkb:JM23(orf name)|uniprotkb:Protein ftsJ homolog 1(gene name synonym)|uniprotkb:2'-O-ribose RNA methyltransferase TRM7 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_036412.1|refseq:NP_803188.1|refseq:NP_001269086.1|refseq:XP_005272652.1|ensembl:ENST00000348411(transcript)|go:"GO:0001510"(RNA methylation)|go:"GO:0002128"(tRNA nucleoside ribose methylation)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008175"(tRNA methyltransferase activity)|go:"GO:0009020"("tRNA (guanosine-2'-O-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0052666"("tRNA (cytosine-2'-O-)-methyltransferase activity")|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR028590|interpro:IPR029063|mint:Q9UET6|reactome:R-HSA-6782315|ensembl:ENSG00000068438(gene)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:N4L9nsU0Wj3FMVjYALdxpx56aZs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P29322	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3905018|ensembl:ENSP00000166244|uniprotkb:Q9P269|uniprotkb:Q9NUA9|uniprotkb:Q6IN80|uniprotkb:Q8IUX6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:epha8_human(display_long)|uniprotkb:EPHA8(gene name)|psi-mi:EPHA8(display_short)|uniprotkb:EEK(gene name synonym)|uniprotkb:KIAA1459(gene name synonym)|uniprotkb:EPH- and ELK-related kinase(gene name synonym)|uniprotkb:EPH-like kinase 3(gene name synonym)|uniprotkb:Tyrosine-protein kinase receptor EEK(gene name synonym)|uniprotkb:HEK3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000070886(gene)|ensembl:ENST00000166244(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005004"(GPI-linked ephrin receptor activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006929"(substrate-dependent cell migration)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016322"(neuron remodeling)|go:"GO:0019838"(growth factor binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR020691|interpro:IPR027936|interpro:IPR036116|rcsb pdb:1UCV|refseq:NP_065387.1|refseq:NP_001006944.1|rcsb pdb:1X5L|rcsb pdb:3KUL|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:T7sTgV46UYcGqs0KJIXmgVbePwI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NP99	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943454|ensembl:ENSP00000244709|uniprotkb:B4DWG2|uniprotkb:K7EJW1|uniprotkb:Q53FL8|uniprotkb:Q5T2C9|uniprotkb:Q86YU1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:trem1_human(display_long)|uniprotkb:TREM1(gene name)|psi-mi:TREM1(display_short)|uniprotkb:Triggering receptor expressed on monocytes 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR039141|rcsb pdb:1Q8M|rcsb pdb:1SMO|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2172127|ensembl:ENSG00000124731(gene)|ensembl:ENST00000244709(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006959"(humoral immune response)|refseq:NP_001229518.1|refseq:NP_001229519.1|refseq:NP_061113.1|refseq:XP_016866445.1|refseq:XP_016866446.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:CcD61qYSjl6xkKd7Gh+ZFVDoURY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6P9A1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943452|ensembl:ENSP00000332861|ensembl:ENSP00000472564|uniprotkb:O43340|uniprotkb:Q9P220	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:zn530_human(display_long)|uniprotkb:ZNF530(gene name)|psi-mi:ZNF530(display_short)|uniprotkb:KIAA1508(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000183647(gene)|ensembl:ENST00000332854(transcript)|ensembl:ENST00000600619(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated  box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|reactome:R-HSA-212436|refseq:NP_001308910.1|refseq:NP_065931.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:iqUuAui27ge53nQvp8mKDFfOqr89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15334	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-299979|ensembl:ENSP00000321537|ensembl:ENSP00000492144|uniprotkb:O00188|uniprotkb:Q58F11|uniprotkb:Q86UK6|uniprotkb:A7MBM7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:l2gl1_human(display_long)|uniprotkb:DLG4(gene name synonym)|uniprotkb:LLGL1(gene name)|psi-mi:LLGL1(display_short)|uniprotkb:Human homolog to the D-lgl gene protein(gene name synonym)|uniprotkb:Hugl-1(gene name synonym)|uniprotkb:HUGL(gene name synonym)|uniprotkb:HUGL1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000131899(gene)|ensembl:ENSG00000284137(gene)|ensembl:ENST00000316843(transcript)|ensembl:ENST00000640494(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007409"(axonogenesis)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0045159"(myosin II binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0000137"(Golgi cis cisterna)|mint:Q15334|refseq:NP_004131.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VqlrgKVnWmXyx1lvnpRe9hRQD0Q9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UEW8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2680974|uniprotkb:Q9UER4|uniprotkb:O14774|uniprotkb:Q53S90|uniprotkb:Q53SL7|uniprotkb:Q53SS1|ensembl:ENSP00000348278|uniprotkb:X5D9C8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stk39_human(display_long)|uniprotkb:SPAK(gene name synonym)|uniprotkb:DCHT(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 39(gene name synonym)|uniprotkb:STK39(gene name)|psi-mi:STK39(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_037365.2|ensembl:ENSG00000198648(gene)|ensembl:ENST00000355999(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050801"(ion homeostasis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1905408"(negative regulation of creatine transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016301"(kinase activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:472OT0D4ddZoxjICU4UOhTOJ4Oo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P54646	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1383852|uniprotkb:Q9H1E8|uniprotkb:Q9UD43|ensembl:ENSP00000360290	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:aapk2_human(display_long)|uniprotkb:PRKAA2(gene name)|psi-mi:PRKAA2(display_short)|uniprotkb:AMPK(gene name synonym)|uniprotkb:AMPK2(gene name synonym)|uniprotkb:Acetyl-CoA carboxylase kinase(gene name synonym)|uniprotkb:Hydroxymethylglutaryl-CoA reductase kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006243.2|dip:DIP-39796N|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047322"("[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity")|go:"GO:0048511"(rhythmic process)|go:"GO:0050405"([acetyl-CoA carboxylase] kinase activity)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0062028"(regulation of stress granule assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0030424"(axon)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR028783|interpro:IPR032270|interpro:IPR039148|mint:P54646|rcsb pdb:2H6D|rcsb pdb:3AQV|rcsb pdb:2LTU|rcsb pdb:2YZA|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6BX6|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|ensembl:ENSG00000162409(gene)|ensembl:ENST00000371244(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:2t/qHlT6HwqoLLbMjjbhOaCZ1Ow9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43716	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6929453|ensembl:ENSP00000446872|uniprotkb:B3KSU7|uniprotkb:Q3KNR8|uniprotkb:Q3B824	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gatc_human(display_long)|uniprotkb:15E1.2(gene name synonym)|uniprotkb:Protein 15E1.2(gene name synonym)|uniprotkb:GATC(gene name)|psi-mi:GATC(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000257218(gene)|ensembl:ENST00000551765(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0030956"("glutamyl-tRNA(Gln) amidotransferase complex")|go:"GO:0032543"(mitochondrial translation)|go:"GO:0050567"("glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity")|go:"GO:0070681"(glutaminyl-tRNAGln biosynthesis via transamidation)|interpro:IPR003837(Glu-tRNAGln amidotransferase, C subunit)|interpro:IPR036113|refseq:NP_789788.1|dip:DIP-48969N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:m/QzCxZNBt9yKuHTOG/qxQw1mL89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N1I0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1059186|uniprotkb:O14584|uniprotkb:O94824|uniprotkb:Q8NB45|ensembl:ENSP00000404179	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dock4_human(display_long)|uniprotkb:DOCK4(gene name)|psi-mi:DOCK4(display_short)|uniprotkb:KIAA0716(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000428084|ensembl:ENSP00000410746|ensembl:ENSP00000404179|refseq:NP_055520.3|refseq:XP_006716251.1|refseq:XP_006716252.1|ensembl:ENSG00000128512(gene)|ensembl:ENST00000437633(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0060326"(cell chemotaxis)|go:"GO:1904694"(negative regulation of vascular associated smooth muscle contraction)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR001452(Src homology-3)|interpro:IPR010703(Dedicator of cytokinesis)|interpro:IPR026791|interpro:IPR027007|interpro:IPR027357|interpro:IPR042455|interpro:IPR043161|interpro:IPR043162|interpro:IPR032376|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-983231|interpro:IPR035769|interpro:IPR035892|interpro:IPR036028|interpro:IPR037014|interpro:IPR037811	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:gfkRZEKBQCgsZ/zjJ8NWqL3uJZk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y587	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2115780|uniprotkb:G3V2N8|uniprotkb:Q9BVE7|uniprotkb:Q86U36|uniprotkb:Q6IAQ4|ensembl:ENSP00000438170|ensembl:ENSP00000451479|ensembl:ENSP00000451609	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ap4s1_human(display_long)|uniprotkb:AP4S1(gene name)|psi-mi:AP4S1(display_short)|uniprotkb:Sigma-1 subunit of AP-4(gene name synonym)|uniprotkb:Sigma-4-adaptin(gene name synonym)|uniprotkb:AP-4 adaptor complex subunit sigma-1(gene name synonym)|uniprotkb:Adaptor-related protein complex 4 subunit sigma-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011534674.1|refseq:XP_011534673.1|refseq:NP_001121598.1|refseq:NP_009008.2|refseq:NP_001241657.1|refseq:NP_001241658.1|refseq:NP_001241655.1|refseq:NP_001241656.1|refseq:XP_005267350.1|ensembl:ENSG00000100478(gene)|ensembl:ENST00000542754(transcript)|ensembl:ENST00000555417(transcript)|ensembl:ENST00000557346(transcript)|go:"GO:0006605"(protein targeting)|go:"GO:0008104"(protein localization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030124"(AP-4 adaptor complex)|go:"GO:0031904"(endosome lumen)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|reactome:R-HSA-432720	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:h2cN+eWIiTGWcjbcc7SONuBe9ik9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75976	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3916308|uniprotkb:B7Z7T9|uniprotkb:B7ZAU4|uniprotkb:F5GZH6|uniprotkb:Q86SH9|uniprotkb:O15377|uniprotkb:Q86XE6|ensembl:ENSP00000225719	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cbpd_human(display_long)|uniprotkb:CPD(gene name)|psi-mi:CPD(display_short)|uniprotkb:Metallocarboxypeptidase D(gene name synonym)|uniprotkb:gp180(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001295.2|refseq:NP_001186704.1|interpro:IPR015567(Peptidase M14B, caboxypeptidase D unit2)|interpro:IPR033848|interpro:IPR034224|mint:O75976|rcsb pdb:5AQ0|reactome:R-HSA-432722|reactome:R-HSA-9696264|reactome:R-HSA-9696273|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|ensembl:ENSG00000108582(gene)|ensembl:ENST00000225719(transcript)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:PC6PFm4D7KoT4utNwyIe57VUwbY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P61927	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2105843|uniprotkb:P02403|uniprotkb:Q6IBB4|uniprotkb:Q99883|uniprotkb:B2R4H2|ensembl:ENSP00000274242	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rl37_human(display_long)|uniprotkb:Large ribosomal subunit protein eL37(gene name synonym)|uniprotkb:RPL37(gene name)|psi-mi:RPL37(display_short)|uniprotkb:G1.16(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000988.1|ensembl:ENSG00000145592(gene)|ensembl:ENST00000274242(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001569(Ribosomal protein L37e)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR018267|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:0WNZ8lgxYeW91kmXUr2VQG1ULZw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5T619	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11985915|ensembl:ENSP00000344129|uniprotkb:B2RP16	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:zn648_human(display_long)|uniprotkb:ZNF648(gene name)|psi-mi:ZNF648(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000179930(gene)|ensembl:ENST00000339948(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|refseq:XP_016855790.1|refseq:XP_016855791.1|refseq:NP_001009992.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4pyaXEPVB3fWe9r0kRwXvjWCOuI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96JX3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-8770074|ensembl:ENSP00000496731|uniprotkb:Q49AT1|uniprotkb:Q5VTX3|uniprotkb:Q6PKF3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:srac1_human(display_long)|uniprotkb:SERAC1(gene name)|psi-mi:SERAC1(display_short)|uniprotkb:Serine active site-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000122335(gene)|ensembl:ENST00000647468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0036148"(phosphatidylglycerol acyl-chain remodeling)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029058|refseq:NP_116250.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:W/XU3lDLki0fPLnWFkETcHckFHY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92796	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-80440|ensembl:ENSP00000363480|uniprotkb:Q9ULI8|uniprotkb:Q5JUW7|uniprotkb:D3DVU5|uniprotkb:B4E0H1|uniprotkb:Q5JUW6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dlg3_human(display_long)|uniprotkb:DLG3(gene name)|psi-mi:DLG3(display_short)|uniprotkb:KIAA1232(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)|uniprotkb:Neuroendocrine-DLG(gene name synonym)|uniprotkb:XLMR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000082458(gene)|ensembl:ENST00000374360(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019900"(kinase binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|rcsb pdb:1UM7|rcsb pdb:2FE5|rcsb pdb:2I1N|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-6794361|reactome:R-HSA-8849932|reactome:R-HSA-9609736|reactome:R-HSA-9617324|reactome:R-HSA-9620244|refseq:NP_001159750.1|refseq:NP_065781.1|refseq:NP_066943.2|refseq:XP_005262305.1|refseq:XP_016884815.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:mnuw5iq2NexP1BL90IuQ1i21xo89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q53H96	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2959680|ensembl:ENSP00000480945|ensembl:ENSP00000488371|uniprotkb:Q9H896|uniprotkb:Q8N3N9|uniprotkb:B3KMB5|uniprotkb:Q96HX4|uniprotkb:B4DVT6|uniprotkb:H0Y6C3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:p5cr3_human(display_long)|uniprotkb:PYCR3(gene name)|psi-mi:PYCR3(display_short)|uniprotkb:PYCRL(gene name synonym)|uniprotkb:Pyrroline-5-carboxylate reductase-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000495276(transcript)|ensembl:ENST00000632107(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0045171"(intercellular bridge)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:Q53H96|reactome:R-HSA-8964539|ensembl:ENSG00000276657(gene)|ensembl:ENSG00000104524(gene)|refseq:NP_075566.2|refseq:NP_001316795.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:n2snI64kwT1vICZ4DA9tmdtS4vU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NR31	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3920694|uniprotkb:B4DQ19|ensembl:ENSP00000362335|ensembl:ENSP00000362338|ensembl:ENSP00000362339|ensembl:ENSP00000399698	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sar1a_human(display_long)|uniprotkb:SAR1A(gene name)|psi-mi:SAR1A(display_short)|uniprotkb:SAR1(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SARA1(gene name synonym)|uniprotkb:COPII-associated small GTPase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000079332(gene)|ensembl:ENST00000373238(transcript)|ensembl:ENST00000373241(transcript)|ensembl:ENST00000373242(transcript)|ensembl:ENST00000431664(transcript)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0061024"(membrane organization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006687(GTP-binding protein SAR1)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:Q9NR31|rcsb pdb:2GAO|refseq:NP_001136120.1|refseq:NP_064535.1|dip:DIP-59790N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Wgq8eFE+YfSt/fs1cpGicDT0rMA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95674	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3913685|uniprotkb:Q5TDY5|uniprotkb:Q5TDY3|uniprotkb:Q5TDY2|uniprotkb:Q9NTT2|uniprotkb:Q9BYK5|uniprotkb:Q5TDY4|uniprotkb:D3DW04|uniprotkb:B2RDC6|ensembl:ENSP00000419879	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cds2_human(display_long)|uniprotkb:CDS2(gene name)|psi-mi:CDS2(display_short)|uniprotkb:CDP-DAG synthase 2(gene name synonym)|uniprotkb:CDP-DG synthase 2(gene name synonym)|uniprotkb:CDP-diacylglycerol synthase 2(gene name synonym)|uniprotkb:CDP-diglyceride pyrophosphorylase 2(gene name synonym)|uniprotkb:CDP-diglyceride synthase 2(gene name synonym)|uniprotkb:"CTP:phosphatidate cytidylyltransferase 2"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003809.1|ensembl:ENSG00000101290(gene)|ensembl:ENST00000460006(transcript)|go:"GO:0004605"(phosphatidate cytidylyltransferase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006655"(phosphatidylglycerol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR000374(Phosphatidate cytidylyltransferase)|interpro:IPR016720(Phosphatidate cytidylyltransferase, eukaryota)|mint:O95674|reactome:R-HSA-1483148	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:tCRLIDMiesBx7QPKIycdX3Igz589606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P27986	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P08236	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2906879|uniprotkb:Q549U0|uniprotkb:Q96CL9|uniprotkb:B4E1F6|uniprotkb:E9PCV0|ensembl:ENSP00000302728	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:bglr_human(display_long)|uniprotkb:GUSB(gene name)|psi-mi:GUSB(display_short)|uniprotkb:Beta-G1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000172.2|refseq:NP_001280033.1|refseq:NP_001280034.1|refseq:XP_005250354.1|refseq:NP_001271219.1|dip:DIP-29724N|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006101(Glycoside hydrolase, family 2)|interpro:IPR006102(Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich)|interpro:IPR006103(Glycoside hydrolase family 2, TIM barrel)|interpro:IPR006104(Glycoside hydrolase family 2, carbohydrate-binding)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR023230|interpro:IPR023232|interpro:IPR036156|mint:P08236|rcsb pdb:1BHG|rcsb pdb:3HN3|reactome:R-HSA-2024096|reactome:R-HSA-2160916|reactome:R-HSA-2206292|reactome:R-HSA-6798695|ensembl:ENSG00000169919(gene)|ensembl:ENST00000304895(transcript)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006027"(glycosaminoglycan catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019391"(glucuronoside catabolic process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030246"(carbohydrate binding)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xF7O30YloSCIuXadCwiBoRBjSjA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H2E6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-311295|uniprotkb:Q9P2H9|ensembl:ENSP00000345512|ensembl:ENSP00000424388	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sem6a_human(display_long)|uniprotkb:SEMA6A(gene name)|psi-mi:SEMA6A(display_short)|uniprotkb:KIAA1368(gene name synonym)|uniprotkb:SEMAQ(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_065847.1|refseq:NP_001287709.1|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0106089"(negative regulation of cell adhesion involved in sprouting angiogenesis)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036352|rcsb pdb:6WTS|reactome:R-HSA-416700|ensembl:ENSG00000092421(gene)|ensembl:ENST00000343348(transcript)|ensembl:ENST00000510263(transcript)|go:"GO:0001755"(neural crest cell migration)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4DFr78PrSaGvR6om5lXlNBZPYt89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z401	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1046479|ensembl:ENSP00000396830|uniprotkb:Q14655|uniprotkb:Q86T77|uniprotkb:Q8IVX2|uniprotkb:Q8NB93|uniprotkb:E7EPL3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mycpp_human(display_long)|uniprotkb:DENN domain-containing protein 4A(gene name synonym)|uniprotkb:DENND4A(gene name)|psi-mi:DENND4A(display_short)|uniprotkb:IRLB(gene name synonym)|uniprotkb:MYCPBP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000431932(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|interpro:IPR001194(DENN)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023341|interpro:IPR037516|ensembl:ENSG00000174485(gene)|mint:Q7Z401|reactome:R-HSA-8876198|refseq:NP_001138295.1|refseq:NP_005839.3|refseq:XP_005254178.1|refseq:XP_016877352.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:mZfgls9XVdT2fGgjJ6y2Q8RumoU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13018	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943450|uniprotkb:B2RTU9|uniprotkb:D3DPB1|uniprotkb:Q13019|uniprotkb:Q15095|uniprotkb:Q53R45|uniprotkb:Q53RR7|ensembl:ENSP00000283243	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pla2r_human(display_long)|uniprotkb:PLA2R1(gene name)|psi-mi:PLA2R1(display_short)|uniprotkb:180 kDa secretory phospholipase A2 receptor(gene name synonym)|uniprotkb:C-type lectin domain family 13 member C(gene name synonym)|uniprotkb:CLEC13C(gene name synonym)|uniprotkb:M-type receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001007268.1|refseq:NP_001182570.1|refseq:NP_031392.3|refseq:XP_005246449.1|refseq:XP_011509122.1|refseq:XP_016859087.1|ensembl:ENSG00000153246(gene)|ensembl:ENST00000283243(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090238"(positive regulation of arachidonic acid secretion)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|go:"GO:1904635"(positive regulation of glomerular visceral epithelial cell apoptotic process)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR036943|rcsb pdb:6JLI|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|reactome:R-HSA-1482925|reactome:R-HSA-1483166|interpro:IPR035992	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:o0lHQyYTqf2x7rND/Ol0jQhbVXM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00442	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1045306|intact:EBI-2513784|uniprotkb:Q5VVL5|uniprotkb:Q5VVL6|uniprotkb:Q96E99|ensembl:ENSP00000359146	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rtca_human(display_long)|uniprotkb:RTCA(gene name)|psi-mi:RTCA(display_short)|uniprotkb:RNA terminal phosphate cyclase domain-containing protein 1(gene name synonym)|uniprotkb:RPC(gene name synonym)|uniprotkb:RPC1(gene name synonym)|uniprotkb:RTC1(gene name synonym)|uniprotkb:RTCD1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001124313.1|refseq:NP_003720.1|ensembl:ENSG00000137996(gene)|ensembl:ENST00000370128(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003963"(RNA-3'-phosphate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR017770(RNA 3'-terminal phosphate cyclase, subgroup)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ELSeAyecjkIjaXMbCgL1j2HSTrQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7RTP6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2555582|uniprotkb:E9PEF0|uniprotkb:Q5U4P4|uniprotkb:Q6ICK4|uniprotkb:Q9P2I3|intact:EBI-2558651|uniprotkb:O94909|uniprotkb:Q96DF2|ensembl:ENSP00000416015|uniprotkb:B2RXJ5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mica3_human(display_long)|uniprotkb:KIAA0819(gene name synonym)|uniprotkb:KIAA1364(gene name synonym)|uniprotkb:MICAL3(gene name)|psi-mi:MICAL3(display_short)|uniprotkb:Molecule interacting with CasL protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001116203.1|refseq:NP_056056.2|go:"GO:0007049"(cell cycle)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042995"(cell projection)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071949"(FAD binding)|go:"GO:0090543"(Flemming body)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR022735|interpro:IPR029941|interpro:IPR036188|interpro:IPR036872|rcsb pdb:2D88|rcsb pdb:5SZG|rcsb pdb:6ICI|go:"GO:0007010"(cytoskeleton organization)|ensembl:ENSG00000243156(gene)|ensembl:ENST00000441493(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|refseq:NP_001129476.1|refseq:XP_005261319.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Ve1WEQHry/REv1IzmmnyGGYd5No9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95801	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1050890|uniprotkb:Q5TA96|uniprotkb:Q9H3I2|uniprotkb:Q53Y95|ensembl:ENSP00000360329	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ttc4_human(display_long)|uniprotkb:TTC4(gene name)|psi-mi:TTC4(display_short)|uniprotkb:My044(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004614.3|ensembl:ENSG00000243725(gene)|ensembl:ENST00000371281(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044059|rcsb pdb:6HFO	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TUGm8TA6JeHZMsObPJECcOCiGA89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75608	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1052185|uniprotkb:O43202|uniprotkb:Q9UQF9|ensembl:ENSP00000320043	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lypa1_human(display_long)|uniprotkb:Lysophospholipase 1(gene name synonym)|uniprotkb:Lysophospholipase I(gene name synonym)|uniprotkb:LYPLA1(gene name)|psi-mi:LYPLA1(display_short)|uniprotkb:APT1(gene name synonym)|uniprotkb:LPL1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006321.1|refseq:NP_001266285.1|refseq:NP_001266286.1|refseq:NP_001266287.1|refseq:NP_001266288.1|refseq:NP_001266289.1|ensembl:ENSG00000120992(gene)|ensembl:ENST00000316963(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0016298"(lipase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042997"(negative regulation of Golgi to plasma membrane protein transport)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058|rcsb pdb:1FJ2|rcsb pdb:5SYM|rcsb pdb:6QGN|go:"GO:0005737"(cytoplasm)|rcsb pdb:6QGO|rcsb pdb:6QGQ|rcsb pdb:6QGS|reactome:R-HSA-203615|reactome:R-HSA-9648002	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:y/NsD5HcH2FjnwUrSCBzeevQU+s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P63000	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-413628|ensembl:ENSP00000258737|uniprotkb:O95501|uniprotkb:P15154|uniprotkb:Q3Y4D3|uniprotkb:Q5JAA8|uniprotkb:Q9BTB4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rac1_human(display_long)|uniprotkb:RAC1(gene name)|psi-mi:RAC1(display_short)|uniprotkb:MIG5(orf name)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Ras-like protein TC25(gene name synonym)|uniprotkb:Cell migration-inducing gene 5 protein(gene name synonym)|uniprotkb:TC25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000136238(gene)|ensembl:ENST00000348035(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006954"(inflammatory response)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042470"(melanosome)|reactome:R-HSA-2424491|refseq:NP_008839.2|refseq:NP_061485.1|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P63000|rcsb pdb:1E96|rcsb pdb:1FOE|rcsb pdb:1G4U|rcsb pdb:1HE1|rcsb pdb:1HH4|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:1MH1|rcsb pdb:1RYF|rcsb pdb:1RYH|rcsb pdb:2FJU|rcsb pdb:2H7V|rcsb pdb:2NZ8|rcsb pdb:2P2L|rcsb pdb:2RMK|rcsb pdb:2VRW|rcsb pdb:2WKP|rcsb pdb:2WKQ|rcsb pdb:2WKR|rcsb pdb:2YIN|rcsb pdb:3B13|rcsb pdb:3BJI|rcsb pdb:3RYT|rcsb pdb:3SBD|rcsb pdb:3SBE|rcsb pdb:3SU8|rcsb pdb:3SUA|rcsb pdb:3TH5|rcsb pdb:4GZL|rcsb pdb:4GZM|rcsb pdb:4YON|rcsb pdb:5FI0|rcsb pdb:5HZH|rcsb pdb:5N6O|rcsb pdb:5O33|rcsb pdb:5QQD|rcsb pdb:5QQE|rcsb pdb:5QQF|rcsb pdb:5QQG|rcsb pdb:5QQH|rcsb pdb:5QQI|rcsb pdb:5QQJ|rcsb pdb:5QQK|rcsb pdb:5QQL|rcsb pdb:5QQM|rcsb pdb:5QQN|rcsb pdb:5QU9|rcsb pdb:6AGP|rcsb pdb:6BC1|rcsb pdb:6TGC|rcsb pdb:6X1G|rcsb pdb:7AJK|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1445148|reactome:R-HSA-164944|reactome:R-HSA-193648|reactome:R-HSA-2029482|reactome:R-HSA-2219530|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|reactome:R-HSA-3928662|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-389359|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-4086400|reactome:R-HSA-416550|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-445144|reactome:R-HSA-5218920|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5668599|reactome:R-HSA-5687128|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-9013149|reactome:R-HSA-9032759|reactome:R-HSA-9032845|reactome:R-HSA-9619229|reactome:R-HSA-9664422|reactome:R-HSA-9673324|reactome:R-HSA-983231|reactome:R-HSA-2871796|reactome:R-HSA-376172|dip:DIP-29260N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6ZN17	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2462592|uniprotkb:B2RPN6|uniprotkb:A1L165|uniprotkb:Q5TCM4|ensembl:ENSP00000344401	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ln28b_human(display_long)|uniprotkb:LIN28B(gene name)|psi-mi:LIN28B(display_short)|uniprotkb:CSDD2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001004317.1|ensembl:ENSG00000187772(gene)|ensembl:ENST00000345080(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0050779"(RNA destabilization)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|go:"GO:2000632"(negative regulation of pre-miRNA processing)|go:"GO:2000635"(negative regulation of primary miRNA processing)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|rcsb pdb:4A4I	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fsajK9bTHAkQUEfwVbobY9jrS9M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15118	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2368710|uniprotkb:Q9P130|uniprotkb:B4DET3|ensembl:ENSP00000269228	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:npc1_human(display_long)|uniprotkb:NPC1(gene name)|psi-mi:NPC1(display_short)|uniprotkb:Niemann-Pick C1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000262.2|dip:DIP-53217N|ensembl:ENSG00000141458(gene)|ensembl:ENST00000269228(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0010467"(gene expression)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045121"(membrane raft)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR003392(Patched)|interpro:IPR004765(Niemann-Pick C type protein)|interpro:IPR032190|rcsb pdb:3GKH|rcsb pdb:3GKI|rcsb pdb:3GKJ|rcsb pdb:3JD8|rcsb pdb:5F18|rcsb pdb:5F1B|rcsb pdb:5HNS|rcsb pdb:5JNX|rcsb pdb:5KWY|rcsb pdb:5U73|rcsb pdb:5U74|rcsb pdb:6UOX|rcsb pdb:6W5R|rcsb pdb:6W5S|rcsb pdb:6W5T|rcsb pdb:6W5U|rcsb pdb:6W5V|reactome:R-HSA-8964038	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3kG4MGzeShC2D5FsPoZZm1lEGlk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8IXH7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NZE8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2809397|uniprotkb:Q8WWA2|uniprotkb:Q658U7|uniprotkb:B2RB93|uniprotkb:A6NKV6|ensembl:ENSP00000338389	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rm35_human(display_long)|uniprotkb:MRPL35(gene name)|psi-mi:MRPL35(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL35m(gene name synonym)|uniprotkb:BM-007(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057706.2|refseq:NP_663619.1|ensembl:ENSG00000132313(gene)|ensembl:ENST00000337109(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR019338|interpro:IPR021137|interpro:IPR037229|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qnBAYkLrqSc62X16EcCAI+Yrtaw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14733	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-492605|uniprotkb:O14648|uniprotkb:O14816|uniprotkb:O60452|uniprotkb:O60453|uniprotkb:Q1PG43|uniprotkb:Q8IY10|uniprotkb:B2R9S5|uniprotkb:D6W659|ensembl:ENSP00000381066	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mp2k7_human(display_long)|uniprotkb:MAPK/ERK kinase 7(gene name synonym)|uniprotkb:JNK-activating kinase 2(gene name synonym)|uniprotkb:c-Jun N-terminal kinase kinase 2(gene name synonym)|uniprotkb:MAP2K7(gene name)|psi-mi:MAP2K7(display_short)|uniprotkb:JNKK2(gene name synonym)|uniprotkb:MKK7(gene name synonym)|uniprotkb:PRKMK7(gene name synonym)|uniprotkb:MEK7(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 4(gene name synonym)|uniprotkb:SKK4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_660186.1|ensembl:ENSG00000076984(gene)|ensembl:ENST00000397979(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009408"(response to heat)|go:"GO:0009411"(response to UV)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904355"(positive regulation of telomere capping)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:O14733|rcsb pdb:2DYL|rcsb pdb:3WZU|rcsb pdb:4UX9|rcsb pdb:5B2K|rcsb pdb:5B2L|rcsb pdb:5B2M|rcsb pdb:5Y8U|rcsb pdb:5Y90|rcsb pdb:5Z1D|rcsb pdb:5Z1E|rcsb pdb:6IB0|rcsb pdb:6IB2|go:"GO:0000187"(obsolete activation of MAPK activity)|rcsb pdb:6QFL|rcsb pdb:6QFR|rcsb pdb:6QFT|rcsb pdb:6QG4|rcsb pdb:6QG7|rcsb pdb:6QHO|rcsb pdb:6QHR|rcsb pdb:6YFZ|rcsb pdb:6YG0|rcsb pdb:6YG1|rcsb pdb:6YG2|rcsb pdb:6YG3|rcsb pdb:6YG4|rcsb pdb:6YG5|rcsb pdb:6YG6|rcsb pdb:6YG7|rcsb pdb:6YZ4|rcsb pdb:7CBX|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-5210891|reactome:R-HSA-450321|refseq:NP_001284484.1|refseq:NP_001284485.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fEJqQ+bmZXzL9rSHk/Z01SQJFKM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NHH9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2410430|uniprotkb:B7Z1X2|ensembl:ENSP00000368237|uniprotkb:Q4ZG30|uniprotkb:Q7Z630|uniprotkb:Q8NHH8|uniprotkb:Q9H5M7|intact:EBI-2559696|uniprotkb:B7Z7X8|intact:EBI-11081412	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:atla2_human(display_long)|uniprotkb:ATL2(gene name)|psi-mi:ATL2(display_short)|uniprotkb:ARL6IP2(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000119787(gene)|ensembl:ENST00000378954(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8NHH9|refseq:NP_001295005.1|refseq:NP_001129145.1|refseq:NP_071769.2|refseq:NP_001317387.1|refseq:NP_001317388.1|refseq:NP_001317389.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:MGye5g/TWQQv39oFMuhF+PUZcRM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q07812	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-516580|uniprotkb:P55269|uniprotkb:Q07814|uniprotkb:Q07815|uniprotkb:Q8WZ49|uniprotkb:Q9NR76|uniprotkb:Q9UQD6|uniprotkb:Q9NYG7|uniprotkb:Q9UCZ6|uniprotkb:Q9UCZ7|uniprotkb:A8K4W1|intact:EBI-8995042|ensembl:ENSP00000263262	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:bax_human(display_long)|uniprotkb:BAX(gene name)|psi-mi:BAX(display_short)|uniprotkb:BCL2L4(gene name synonym)|uniprotkb:Bcl-2-like protein 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004315.1|refseq:NP_620116.1|refseq:NP_620118.1|refseq:NP_620119.2|refseq:XP_016882566.1|refseq:NP_001278357.1|refseq:NP_001278360.1|dip:DIP-232N|ensembl:ENSG00000087088(gene)|ensembl:ENST00000345358(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001764"(neuron migration)|go:"GO:0001777"(T cell homeostatic proliferation)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001822"(kidney development)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001844"(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0002358"(B cell homeostatic proliferation)|go:"GO:0002904"(positive regulation of B cell apoptotic process)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006808"(regulation of nitrogen utilization)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007281"(germ cell development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008289"(lipid binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009566"(fertilization)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009651"(response to salt stress)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032976"(release of matrix enzymes from mitochondria)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045136"(development of secondary sexual characteristics)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048087"(positive regulation of developmental pigmentation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0048678"(response to axon injury)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051087"(chaperone binding)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060011"(Sertoli cell proliferation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097144"(BAX complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015267"(channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021854"(hypothalamus development)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902445"(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:"GO:1902512"(positive regulation of apoptotic DNA fragmentation)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1990117"(B cell receptor apoptotic signaling pathway)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026304|interpro:IPR036834|mint:Q07812|rcsb pdb:1F16|rcsb pdb:2G5B|rcsb pdb:2K7W|rcsb pdb:2LR1|rcsb pdb:3PK1|rcsb pdb:3PL7|rcsb pdb:4BD2|rcsb pdb:4BD6|rcsb pdb:4BD7|rcsb pdb:4BD8|rcsb pdb:4BDU|rcsb pdb:4S0O|rcsb pdb:4S0P|rcsb pdb:4UF2|rcsb pdb:4ZIE|rcsb pdb:4ZIF|rcsb pdb:4ZIG|rcsb pdb:4ZIH|rcsb pdb:4ZII|rcsb pdb:5W5X|rcsb pdb:5W5Z|rcsb pdb:5W60|rcsb pdb:5W61|rcsb pdb:6EB6|rcsb pdb:6L8V|rcsb pdb:6L95|rcsb pdb:6TRR|rcsb pdb:6XY6|reactome:R-HSA-111457|reactome:R-HSA-114294|reactome:R-HSA-5620971|reactome:R-HSA-6803204|reactome:R-HSA-6804114|reactome:R-HSA-8878166|reactome:R-HSA-9603505|go:"GO:0097193"(intrinsic apoptotic signaling pathway)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+Fz2No3HFxN4vZ+KGhDcgPQhpLo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BQB6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6256462|ensembl:ENSP00000378426|uniprotkb:A6NIQ6|uniprotkb:B2R4Z6|uniprotkb:Q6UX90|uniprotkb:Q7Z2R4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:vkor1_human(display_long)|uniprotkb:VKORC1(gene name)|psi-mi:VKORC1(display_short)|uniprotkb:VKOR(gene name synonym)|uniprotkb:Vitamin K1 2,3-epoxide reductase subunit 1(gene name synonym)|uniprotkb:MSTP134(orf name)|uniprotkb:MSTP576(orf name)|uniprotkb:UNQ308/PRO351(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000167397(gene)|ensembl:ENST00000394975(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017144"|go:"GO:0017187"(peptidyl-glutamic acid carboxylation)|go:"GO:0042373"(vitamin K metabolic process)|go:"GO:0047057"("vitamin-K-epoxide reductase (warfarin-sensitive) activity")|go:"GO:0048038"(quinone binding)|go:"GO:0060348"(bone development)|interpro:IPR012932(Vitamin K epoxide reductase)|interpro:IPR038354|interpro:IPR042406|mint:Q9BQB6|rcsb pdb:6WV3|rcsb pdb:6WV4|rcsb pdb:6WV5|rcsb pdb:6WV6|rcsb pdb:6WV7|rcsb pdb:6WVH|reactome:R-HSA-6806664|refseq:NP_001298240.1|refseq:NP_076869.1|refseq:NP_996560.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:C3RrQ+y7Huai7PExa9LOvfqni+U9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N0U8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11337915|uniprotkb:E7ETM5|uniprotkb:Q6AHW9|uniprotkb:B4E222|uniprotkb:Q6TEK6|ensembl:ENSP00000353998|ensembl:ENSP00000497394	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:vkorl_human(display_long)|uniprotkb:VKORC1L1(gene name)|psi-mi:VKORC1L1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001271271.1|refseq:NP_775788.2|ensembl:ENSG00000196715(gene)|ensembl:ENST00000360768(transcript)|ensembl:ENST00000648179(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017187"(peptidyl-glutamic acid carboxylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042373"(vitamin K metabolic process)|go:"GO:0047057"("vitamin-K-epoxide reductase (warfarin-sensitive) activity")|go:"GO:0048038"(quinone binding)|interpro:IPR012932(Vitamin K epoxide reductase)|interpro:IPR038354|interpro:IPR042406|mint:Q8N0U8|reactome:R-HSA-6806664	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:0gdoyZTMoqEjTsPOfeUNSlH4M7k9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P83111	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2878119|ensembl:ENSP00000261893|uniprotkb:P83096	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lactb_human(display_long)|uniprotkb:LACTB(gene name)|psi-mi:LACTB(display_short)|uniprotkb:MRPL56(gene name synonym)|uniprotkb:UNQ843/PRO1781(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000103642(gene)|ensembl:ENST00000261893(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|refseq:NP_116246.2|refseq:NP_741982.1|refseq:NP_001275514.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:idqlmN9YYs76X8+d8+4LALz5WjM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5HYI7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11096782|uniprotkb:Q7Z380|uniprotkb:E9PB57|uniprotkb:Q8NB92|uniprotkb:B4DL65|ensembl:ENSP00000424798	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mtx3_human(display_long)|uniprotkb:MTX3(gene name)|psi-mi:MTX3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001010891.4|refseq:NP_001161213.1|refseq:XP_005248552.1|ensembl:ENSG00000177034(gene)|ensembl:ENST00000512528(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0015031"(protein transport)|go:"GO:0140275"(MIB complex)|interpro:IPR017410(Metaxin)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:0UcgXRWBfAYN0A3fYRPRrgnOcXA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P08572	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2432506|uniprotkb:Q14052|uniprotkb:Q548C3|uniprotkb:Q5VZA9|uniprotkb:Q66K23|ensembl:ENSP00000353654	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:co4a2_human(display_long)|uniprotkb:COL4A2(gene name)|psi-mi:COL4A2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001837.2|ensembl:ENSG00000134871(gene)|ensembl:ENST00000360467(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005587"(collagen type IV trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007568"(aging)|go:"GO:0014823"(response to activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR001442(Type 4 procollagen, C-terminal repeat)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036954|rcsb pdb:1LI1|rcsb pdb:5NAX|rcsb pdb:5NB2|rcsb pdb:6MPX|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8948216	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:2jSdn1hb9JtAPdSLo82KAbqdzr09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5VZ89	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2871535|uniprotkb:Q9NWT3|uniprotkb:A2A3R9|uniprotkb:Q6ZUB3|uniprotkb:Q9NUT1|uniprotkb:A2A3R1|uniprotkb:Q6AI48|uniprotkb:A2A3R2|uniprotkb:Q9H6N4|uniprotkb:Q9NWA5|uniprotkb:A2A3R3|uniprotkb:Q8NCY7|uniprotkb:R4GN35|uniprotkb:R4GNB2|intact:EBI-28974130|ensembl:ENSP00000473565	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:den4c_human(display_long)|uniprotkb:DENND4C(gene name)|psi-mi:DENND4C(display_short)|uniprotkb:C9orf55(gene name synonym)|uniprotkb:C9orf55B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000434457|ensembl:ENSP00000473469|ensembl:ENSP00000473565|refseq:NP_001317569.1|refseq:NP_060395.5|ensembl:ENSG00000137145(gene)|ensembl:ENST00000602925(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023341|interpro:IPR037516|interpro:IPR043153|reactome:R-HSA-8876198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:kc65D0Vb3SHO6xMWZ1TC25Tp/Nw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P51784	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q16563	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2800683|uniprotkb:A4D0R2|uniprotkb:Q96AR8|ensembl:ENSP00000011473	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sypl1_human(display_long)|uniprotkb:SYPL(gene name synonym)|uniprotkb:Pantophysin(gene name synonym)|uniprotkb:SYPL1(gene name)|psi-mi:SYPL1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006745.1|refseq:NP_874384.1|ensembl:ENSG00000008282(gene)|ensembl:ENST00000011473(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR008253(Marvel)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:kw4EuKqd6PhotpKiicCjB99ZZCY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q16822	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2825219|uniprotkb:O43253|uniprotkb:Q9BV62|intact:EBI-3189808|uniprotkb:Q86U01|ensembl:ENSP00000216780|ensembl:ENSP00000494919|uniprotkb:B4DW73	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pckgm_human(display_long)|uniprotkb:PCK2(gene name)|psi-mi:PCK2(display_short)|uniprotkb:PEPCK2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001278485.1|refseq:NP_001294983.1|refseq:NP_001018083.2|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033993"(response to lipid)|go:"GO:0042594"(response to starvation)|go:"GO:0046327"(glycerol biosynthetic process from pyruvate)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR008209(Phosphoenolpyruvate carboxykinase, GTP-utilising)|interpro:IPR008210(Phosphoenolpyruvate carboxykinase, N-terminal)|interpro:IPR013035(Phosphoenolpyruvate carboxykinase, C-terminal)|interpro:IPR018091|interpro:IPR035077|interpro:IPR035078|mint:Q16822|reactome:R-HSA-70263|go:"GO:0030145"(manganese ion binding)|ensembl:ENSG00000100889(gene)|ensembl:ENSG00000285241(gene)|ensembl:ENST00000216780(transcript)|ensembl:ENST00000645217(transcript)|go:"GO:0004611"(phosphoenolpyruvate carboxykinase activity)|go:"GO:0004613"("phosphoenolpyruvate carboxykinase (GTP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006116"(NADH oxidation)|go:"GO:0019543"(propionate catabolic process)|refseq:NP_004554.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:gbQbu8+tVa1xs/fKesefSJlpSaM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95563	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-719403|uniprotkb:Q3SXR6|uniprotkb:Q6FIF3|uniprotkb:A8K261|ensembl:ENSP00000271373|ensembl:ENSP00000356820	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mpc2_human(display_long)|uniprotkb:MPC2(gene name)|psi-mi:MPC2(display_short)|uniprotkb:BRP44(gene name synonym)|uniprotkb:Brain protein 44(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001137146.1|refseq:NP_056230.1|reactome:R-HSA-70268|ensembl:ENSG00000143158(gene)|ensembl:ENST00000271373(transcript)|ensembl:ENST00000367846(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006850"(mitochondrial pyruvate transmembrane transport)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0050833"(pyruvate transmembrane transporter activity)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR005336(Protein of unknown function UPF0041)|refseq:XP_006711329.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:smUowwyyXsnLu4q2jX26Iope4Fs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6L8Q7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2515865|ensembl:ENSP00000309142|uniprotkb:Q8IYU3|uniprotkb:Q8NDU2|uniprotkb:Q8TE78|uniprotkb:B4DTU8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pde12_human(display_long)|uniprotkb:PDE12(gene name)|psi-mi:PDE12(display_short)|uniprotkb:Mitochondrial deadenylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000311180(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000958"(mitochondrial mRNA catabolic process)|go:"GO:0004527"(exonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0034611"(oligoribonucleotidase activity)|go:"GO:0035457"(cellular response to interferon-alpha)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|ensembl:ENSG00000174840(gene)|interpro:IPR036691|mint:Q6L8Q7|rcsb pdb:4Z0V|rcsb pdb:4Z2B|rcsb pdb:4ZKF|reactome:R-HSA-8983711|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|refseq:NP_808881.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:P2ALFhSP4Qnqnd08vmkOcVoXe/I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92888	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-465400|uniprotkb:O00513|uniprotkb:Q8N4J4|uniprotkb:Q96BF4|uniprotkb:Q96F17|uniprotkb:Q9BSB1|uniprotkb:Q6NX52|ensembl:ENSP00000346532	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:arhg1_human(display_long)|uniprotkb:ARHGEF1(gene name)|psi-mi:ARHGEF1(display_short)|uniprotkb:115 kDa guanine nucleotide exchange factor(gene name synonym)|uniprotkb:Sub1.5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004697.2|refseq:NP_945328.1|refseq:NP_945353.1|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000076928(gene)|ensembl:ENST00000354532(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036305|interpro:IPR037887|interpro:IPR041020|mint:Q92888|rcsb pdb:1IAP|rcsb pdb:1SHZ|rcsb pdb:3AB3|rcsb pdb:3ODO|rcsb pdb:3ODW|rcsb pdb:3ODX|rcsb pdb:3P6A	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:XIZmflM2cr80ZBD3FO21IDMnInE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43402	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14681	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2339413|uniprotkb:Q9BUQ1|uniprotkb:A8K7D6|uniprotkb:B4DKL6|ensembl:ENSP00000278903|ensembl:ENSP00000484510	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ei24_human(display_long)|uniprotkb:EI24(gene name)|psi-mi:EI24(display_short)|uniprotkb:PIG8(gene name synonym)|uniprotkb:p53-induced gene 8 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011541371.1|refseq:NP_001277064.1|refseq:NP_004870.3|ensembl:ENSG00000149547(gene)|ensembl:ENST00000278903(transcript)|ensembl:ENST00000620753(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061676"(importin-alpha family protein binding)|interpro:IPR009890(Etoposide-induced 2.4)|mint:O14681	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:mb5BoJ3ithOKYe8mN+ZRB4UoltI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y256	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11928602|ensembl:ENSP00000309163|uniprotkb:Q52LZ9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:face2_human(display_long)|uniprotkb:RCE1(gene name)|psi-mi:RCE1(display_short)|uniprotkb:FACE2(gene name synonym)|uniprotkb:Farnesylated proteins-converting enzyme 2(gene name synonym)|uniprotkb:Prenyl protein-specific endoprotease 2(gene name synonym)|uniprotkb:RCE1 homolog(gene name synonym)|uniprotkb:RCE1A(gene name synonym)|uniprotkb:RCE1B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000173653(gene)|ensembl:ENST00000309657(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0018342"(protein prenylation)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071586"(CAAX-box protein processing)|interpro:IPR003675(Abortive infection protein)|interpro:IPR039731|reactome:R-HSA-5689880|reactome:R-HSA-9648002|refseq:NP_001027450.1|refseq:NP_005124.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:paSc2ktiQwtJ1vYzL0z0+YMZoFs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92600	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-357079|uniprotkb:Q96IX4|uniprotkb:B2RPI0|uniprotkb:B7Z1E5|uniprotkb:B5MDQ4|ensembl:ENSP00000273064|ensembl:ENSP00000443687	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cnot9_human(display_long)|uniprotkb:Cell differentiation protein RQCD1 homolog(gene name synonym)|uniprotkb:RCD1(gene name synonym)|uniprotkb:RQCD1(gene name synonym)|uniprotkb:CNOT9(gene name)|psi-mi:CNOT9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	dip:DIP-46840N|refseq:NP_005435.1|refseq:NP_001258564.1|refseq:NP_001258563.1|ensembl:ENSG00000144580(gene)|ensembl:ENST00000273064(transcript)|ensembl:ENST00000542068(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0007548"(sex differentiation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:2FV2|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:5LSW|rcsb pdb:5ONA|rcsb pdb:5ONB|rcsb pdb:6HOM|rcsb pdb:6HON|reactome:R-HSA-429947|reactome:R-HSA-5617472|reactome:R-HSA-6804115	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/oDjYD0axKIkLMKxmji2q+sg+K49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H1I8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-711197|uniprotkb:Q4TT54|uniprotkb:Q8TAZ0|uniprotkb:Q9H711|ensembl:ENSP00000305502|ensembl:ENSP00000380877|uniprotkb:Q9H9D6|uniprotkb:B7Z8E0|uniprotkb:F5H6J9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ascc2_human(display_long)|uniprotkb:ASC-1 complex subunit p100(gene name synonym)|uniprotkb:Trip4 complex subunit p100(gene name synonym)|uniprotkb:ASCC2(gene name)|psi-mi:ASCC2(display_short)|uniprotkb:ASC1P100(gene name synonym)|uniprotkb:RQT3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_115580.2|ensembl:ENSG00000100325(gene)|ensembl:ENST00000307790(transcript)|ensembl:ENST00000397771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0099053"(activating signal cointegrator 1 complex)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041800|rcsb pdb:2DI0|rcsb pdb:6YXQ|reactome:R-HSA-112126|refseq:XP_005261832.1|refseq:NP_001229835.1|refseq:XP_016884487.1|refseq:XP_016884488.1|refseq:XP_016884489.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:aml0rAAbXH3AzmuVZEmwegUA10k9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P50897	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1237011|intact:EBI-2859371|uniprotkb:Q6FGQ4|uniprotkb:B4DY24|ensembl:ENSP00000432053|ensembl:ENSP00000493153	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ppt1_human(display_long)|uniprotkb:PPT1(gene name)|psi-mi:PPT1(display_short)|uniprotkb:PPT(gene name synonym)|uniprotkb:Palmitoyl-protein hydrolase 1(gene name synonym)|uniprotkb:CLN1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000301.1|refseq:NP_001136076.1|ensembl:ENSG00000131238(gene)|ensembl:ENST00000529905(transcript)|ensembl:ENST00000642050(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0007625"(grooming behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016790"(thiolester hydrolase activity)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031579"(membrane raft organization)|go:"GO:0032429"(regulation of phospholipase A2 activity)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048666"(neuron development)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050896"(response to stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120146"(sulfatide binding)|interpro:IPR002472(Palmitoyl protein thioesterase)|interpro:IPR029058|interpro:IPR030294|mint:P50897|rcsb pdb:3GRO|reactome:R-HSA-75105|go:"GO:0043524"(negative regulation of neuron apoptotic process)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:2G1ae6m4OZsMiRzro/2JmWiOOMA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y2G5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2512252|ensembl:ENSP00000339613|uniprotkb:Q6PJV1|uniprotkb:Q8WWU6|uniprotkb:Q9UFY3|uniprotkb:Q9BQS5|uniprotkb:Q7Z4N0|uniprotkb:Q9BQS4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ofut2_human(display_long)|uniprotkb:POFUT2(gene name)|psi-mi:POFUT2(display_short)|uniprotkb:C21orf80(gene name synonym)|uniprotkb:FUT13(gene name synonym)|uniprotkb:KIAA0958(gene name synonym)|uniprotkb:Peptide-O-fucosyltransferase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000186866(gene)|ensembl:ENST00000349485(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006004"(fucose metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0036066"(protein O-linked fucosylation)|go:"GO:0046922"(peptide-O-fucosyltransferase activity)|go:"GO:0051046"(regulation of secretion)|go:"GO:1903334"(positive regulation of protein folding)|interpro:IPR019378|rcsb pdb:4AP5|rcsb pdb:4AP6|reactome:R-HSA-5173214|refseq:NP_056042.1|refseq:NP_598368.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:mddxUsRIT26cLtwaiPaQrEINwFA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q14865	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1210388|uniprotkb:B4DLB3|uniprotkb:Q05DG6|uniprotkb:Q32Q59|uniprotkb:Q6NZ42|uniprotkb:Q5VST4|uniprotkb:Q7Z3M4|uniprotkb:Q8N421|uniprotkb:Q9H786|ensembl:ENSP00000279873	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ari5b_human(display_long)|uniprotkb:ARID5B(gene name)|psi-mi:ARID5B(display_short)|uniprotkb:DESRT(gene name synonym)|uniprotkb:MRF2(gene name synonym)|uniprotkb:MRF1-like protein(gene name synonym)|uniprotkb:Modulator recognition factor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_115575.1|refseq:NP_001231567.1|ensembl:ENSG00000150347(gene)|ensembl:ENST00000279873(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030325"(adrenal gland development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR030408|interpro:IPR036431|mint:Q14865|rcsb pdb:1IG6|rcsb pdb:2OEH|reactome:R-HSA-3214842|go:"GO:0005654"(nucleoplasm)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:B6FNUWNl796yE+jX/0cAknrAkuo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q12756	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2679809|uniprotkb:Q59GH1|uniprotkb:Q53T78|uniprotkb:Q2NKJ6|uniprotkb:Q7KZ57|uniprotkb:Q14752|uniprotkb:Q6P1R9|uniprotkb:Q4LE42|uniprotkb:O95068|uniprotkb:Q63Z40|uniprotkb:Q13355|uniprotkb:B0I1S5|uniprotkb:F5H045|ensembl:ENSP00000497030|ensembl:ENSP00000497824	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kif1a_human(display_long)|uniprotkb:ATSV(gene name synonym)|uniprotkb:C2orf20(gene name synonym)|uniprotkb:Axonal transporter of synaptic vesicles(gene name synonym)|uniprotkb:Microtubule-based motor KIF1A(gene name synonym)|uniprotkb:Unc-104- and KIF1A-related protein(gene name synonym)|uniprotkb:KIF1A(gene name)|psi-mi:KIF1A(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001307634.1|refseq:NP_001230937.1|refseq:NP_004312.2|refseq:XP_016859880.1|dip:DIP-42405N|ensembl:ENSG00000130294(gene)|ensembl:ENST00000649096(transcript)|ensembl:ENST00000650053(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:4EGX|rcsb pdb:4EJQ|rcsb pdb:4UXO|rcsb pdb:4UXP|rcsb pdb:4UXS|reactome:R-HSA-6811434|reactome:R-HSA-983189|rcsb pdb:4UXR	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Gbsm6W6Tbp/2sEvu8qm9lyCfwS09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q00013	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-711788|uniprotkb:B4DZV5|uniprotkb:Q5J7V5|uniprotkb:G3XAI1|uniprotkb:Q2TSB6|ensembl:ENSP00000358547	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:em55_human(display_long)|uniprotkb:Membrane protein, palmitoylated 1(gene name synonym)|uniprotkb:MPP1(gene name)|psi-mi:MPP1(display_short)|uniprotkb:EMP55(gene name synonym)|uniprotkb:DXS552E(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001159932.1|refseq:NP_001159933.1|refseq:NP_001159934.1|refseq:NP_002427.1|ensembl:ENSG00000130830(gene)|ensembl:ENST00000369534(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032420"(stereocilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090022"(regulation of neutrophil chemotaxis)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035475|interpro:IPR036028|interpro:IPR036034|mint:Q00013|rcsb pdb:2EJY|rcsb pdb:2EV8|rcsb pdb:3NEY|reactome:R-HSA-9662361	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:b9QmIlmQ5SZHnOQfGSezmcvaDls9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H7H0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P30838	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3905126|uniprotkb:Q9BT37|uniprotkb:A8K828|ensembl:ENSP00000225740|ensembl:ENSP00000388469|ensembl:ENSP00000411821	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:al3a1_human(display_long)|uniprotkb:ALDH3A1(gene name)|psi-mi:ALDH3A1(display_short)|uniprotkb:ALDH3(gene name synonym)|uniprotkb:ALDHIII(gene name synonym)|uniprotkb:Aldehyde dehydrogenase 3(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 3 member A1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000682.3|refseq:NP_001128639.1|refseq:NP_001128640.1|ensembl:ENSG00000108602(gene)|ensembl:ENST00000225740(transcript)|ensembl:ENST00000444455(transcript)|ensembl:ENST00000457500(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018479"("benzaldehyde dehydrogenase (NAD+) activity")|go:"GO:0042493"|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051591"(response to cAMP)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|rcsb pdb:3SZA|rcsb pdb:3SZB|rcsb pdb:4H80|rcsb pdb:4L1O|rcsb pdb:4L2O|reactome:R-HSA-211945	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bpEh9WjDg9iuy1HpIXGzf8idWsI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P51649	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2684180|uniprotkb:Q546H9|uniprotkb:B2RD26|uniprotkb:G5E949|uniprotkb:Q8N3W6|ensembl:ENSP00000350191	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ssdh_human(display_long)|uniprotkb:SSADH(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 5 member A1(gene name synonym)|uniprotkb:"NAD(+)-dependent succinic semialdehyde dehydrogenase"(gene name synonym)|uniprotkb:ALDH5A1(gene name)|psi-mi:ALDH5A1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001071.1|refseq:NP_733936.1|ensembl:ENSG00000112294(gene)|ensembl:ENST00000357578(transcript)|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0009450"(gamma-aminobutyric acid catabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR010102(Succinic semialdehyde dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51649|rcsb pdb:2W8N|rcsb pdb:2W8O|rcsb pdb:2W8P|rcsb pdb:2W8Q|rcsb pdb:2W8R|reactome:R-HSA-916853	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:gCoItLXLp6W0Cr45kAu+XwADFAs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7LBC6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2511832|ensembl:ENSP00000326563|uniprotkb:Q9BW93|uniprotkb:Q9BZ52|uniprotkb:Q9BVH6|uniprotkb:A6H8X7|uniprotkb:Q9UPS0|uniprotkb:Q9NYF4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kdm3b_human(display_long)|uniprotkb:KDM3B(gene name)|psi-mi:KDM3B(display_short)|uniprotkb:C5orf7(gene name synonym)|uniprotkb:JHDM2B(gene name synonym)|uniprotkb:JMJD1B(gene name synonym)|uniprotkb:KIAA1082(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2B(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1B(gene name synonym)|uniprotkb:Nuclear protein 5qNCA(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3B"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000120733(gene)|ensembl:ENST00000314358(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016209"(antioxidant activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0072718"(response to cisplatin)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q7LBC6|rcsb pdb:4C8D|rcsb pdb:5R7X|rcsb pdb:5RAA|rcsb pdb:5RAC|rcsb pdb:5RAD|rcsb pdb:5RAE|rcsb pdb:5RAF|rcsb pdb:5RAG|rcsb pdb:5RAH|rcsb pdb:5RAI|rcsb pdb:5RAJ|rcsb pdb:5RAK|rcsb pdb:5RAL|rcsb pdb:5RAM|rcsb pdb:5RAN|rcsb pdb:5RAO|rcsb pdb:5RAP|rcsb pdb:5RAQ|rcsb pdb:5RAR|rcsb pdb:5RAS|rcsb pdb:5RAB|rcsb pdb:5RAU|rcsb pdb:5RAV|rcsb pdb:5RAW|rcsb pdb:5RAX|rcsb pdb:5RAY|rcsb pdb:5RAZ|rcsb pdb:5RB0|rcsb pdb:5RB1|rcsb pdb:5RB2|rcsb pdb:5RB3|rcsb pdb:5RB4|rcsb pdb:5RB5|rcsb pdb:5RB6|rcsb pdb:5RB7|rcsb pdb:6RBJ|reactome:R-HSA-3214842|refseq:NP_057688.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:dtc0EOaZYDVEh5p1xgHE9uq2YVs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96HC4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-751267|uniprotkb:Q8WVK0|uniprotkb:O60705|uniprotkb:A8K6F9|uniprotkb:Q5UW38|uniprotkb:D6RB78|uniprotkb:E9PBF5|uniprotkb:Q56VN4|ensembl:ENSP00000321746	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pdli5_human(display_long)|uniprotkb:Enigma homolog(gene name synonym)|uniprotkb:Enigma-like PDZ and LIM domains protein(gene name synonym)|uniprotkb:PDLIM5(gene name)|psi-mi:PDLIM5(display_short)|uniprotkb:L9(orf name)|uniprotkb:ENH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001011515.1|refseq:NP_001011516.1|refseq:NP_006448.4|refseq:NP_001243358.1|mint:Q96HC4|rcsb pdb:2DAR|rcsb pdb:2UZC|reactome:R-HSA-6794361|interpro:IPR036034|ensembl:ENSG00000163110(gene)|ensembl:ENST00000317968(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0042805"(actinin binding)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061061"(muscle structure development)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|go:"GO:0005829"(cytosol)|dip:DIP-34898N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Ngp310yfoOv8KaxchoUc39mj5HE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13445	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4310995|ensembl:ENSP00000214869	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tmed1_human(display_long)|uniprotkb:TMED1(gene name)|psi-mi:TMED1(display_short)|uniprotkb:IL1RL1L(gene name synonym)|uniprotkb:IL1RL1LG(gene name synonym)|uniprotkb:Interleukin-1 receptor-like 1 ligand(gene name synonym)|uniprotkb:Putative T1/ST2 receptor-binding protein(gene name synonym)|uniprotkb:p24 family protein gamma-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006849.1|ensembl:ENSG00000099203(gene)|ensembl:ENST00000214869(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|mint:Q13445	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:PQHIGiwN0HhCGcpm1HGn/WF3t9U9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P17540	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-712973|ensembl:ENSP00000254035|ensembl:ENSP00000404203|ensembl:ENSP00000410289|uniprotkb:Q6ICS8|uniprotkb:Q8N1E1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kcrs_human(display_long)|uniprotkb:Sarcomeric mitochondrial creatine kinase(gene name synonym)|uniprotkb:Basic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:CKMT2(gene name)|psi-mi:CKMT2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000131730(gene)|ensembl:ENST00000254035(transcript)|ensembl:ENST00000424301(transcript)|ensembl:ENST00000437669(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|rcsb pdb:4Z9M|reactome:R-HSA-71288|refseq:NP_001093205.1|refseq:NP_001093206.1|refseq:NP_001816.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:pNfPae/Rcr7bEKeSp3ifv+CDN7Q9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6ZXV5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10188441|uniprotkb:Q5H9T6|uniprotkb:Q68DX0|uniprotkb:Q7Z332|uniprotkb:Q8NC50|uniprotkb:Q5CZ86|uniprotkb:Q68DQ6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tmtc3_human(display_long)|uniprotkb:Transmembrane and TPR repeat-containing protein 3(gene name synonym)|uniprotkb:TMTC3(gene name)|psi-mi:TMTC3(display_short)|uniprotkb:Protein SMILE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013618(Region of unknown function DUF1736)|interpro:IPR019734|refseq:NP_861448.2|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|mint:Q6ZXV5	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:6i1GfYE+o3deUrrHGC7038LPCuw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HB66	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1054754|ensembl:ENSP00000497510	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:q9hb66_human(display_long)|uniprotkb:MKKS(gene name)|psi-mi:MKKS(display_short)|uniprotkb:hCG_40237(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000285723(gene)|ensembl:ENST00000649912(transcript)|go:"GO:0016021"(integral component of membrane)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:uMf1kaANmvBuAqa4Ou0LtJQLwE49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H773	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-723569|intact:EBI-1384169|ensembl:ENSP00000322524	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dctp1_human(display_long)|uniprotkb:DCTPP1(gene name)|psi-mi:DCTPP1(display_short)|uniprotkb:RS21C6(gene name synonym)|uniprotkb:CDA03(orf name)|uniprotkb:XTP3TPA(gene name synonym)|uniprotkb:Deoxycytidine-triphosphatase 1(gene name synonym)|uniprotkb:XTP3-transactivated gene A protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_077001.1|ensembl:ENST00000319285(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006253"(dCTP catabolic process)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0032556"(pyrimidine deoxyribonucleotide binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0047840"(dCTP diphosphatase activity)|interpro:IPR025984|mint:Q9H773|reactome:R-HSA-499943|ensembl:ENSG00000179958(gene)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4EfV2ZU2MgDiFXShthfualZnat09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N752	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1383554|uniprotkb:Q5T2N2|ensembl:ENSP00000369126	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kc1al_human(display_long)|uniprotkb:CSNK1A1L(gene name)|psi-mi:CSNK1A1L(display_short)|uniprotkb:CK1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_660204.2|ensembl:ENSG00000180138(gene)|ensembl:ENST00000379800(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0106310"(protein serine kinase activity)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:kUS95J2/KbZH0T5iV4fRsAprpR49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43929	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-374889|uniprotkb:B7Z5F1|uniprotkb:F5H069|uniprotkb:Q96C42|ensembl:ENSP00000264169|ensembl:ENSP00000376597|ensembl:ENSP00000441953|uniprotkb:D3DP86|uniprotkb:B7Z3D0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:orc4_human(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:ORC4L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000115947(gene)|ensembl:ENST00000264169(transcript)|ensembl:ENST00000392857(transcript)|ensembl:ENST00000535373(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000808"(origin recognition complex)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|interpro:IPR041664|mint:O43929|rcsb pdb:5UJ7|rcsb pdb:5UJM|rcsb pdb:7CTE|rcsb pdb:7CTF|rcsb pdb:7CTG|rcsb pdb:7JPO|rcsb pdb:7JPP|rcsb pdb:7JPQ|rcsb pdb:7JPR|rcsb pdb:7JPS|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-68616|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|refseq:XP_011509557.1|refseq:NP_001177808.1|refseq:NP_002543.2|refseq:NP_859525.1|refseq:NP_859526.1|refseq:XP_016859715.1|refseq:NP_001177810.1|refseq:NP_001177811.1|refseq:XP_016859716.1|dip:DIP-29690N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fo+Suy/Q9ElX4ryKHMSH+Jzkpfs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:I3L2B0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943448|ensembl:ENSP00000459540	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:i3l2b0_human(display_long)|uniprotkb:CLUH(gene name)|psi-mi:CLUH(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000132361(gene)|ensembl:ENST00000574426(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023231|interpro:IPR025697|interpro:IPR027523|interpro:IPR028275|interpro:IPR033646	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:vRP3kplRyAmacQfu4YIf6mUIrFg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UBI6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358636|uniprotkb:Q9BRV5|ensembl:ENSP00000360021|uniprotkb:Q69YP5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gbg12_human(display_long)|uniprotkb:GNG12(gene name)|psi-mi:GNG12(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_061329.3|ensembl:ENSG00000172380(gene)|ensembl:ENST00000370982(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|refseq:XP_016857298.1|refseq:XP_016857299.1|refseq:XP_016857300.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:rCPylE+1WWtdSzfdOd61jXbvM9M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P31483	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1387216|uniprotkb:Q53SS9|uniprotkb:Q96B58|ensembl:ENSP00000401371	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tia1_human(display_long)|uniprotkb:TIA1(gene name)|psi-mi:TIA1(display_short)|uniprotkb:p40-TIA-1(gene name synonym)|uniprotkb:RNA-binding protein TIA-1(gene name synonym)|uniprotkb:T-cell-restricted intracellular antigen-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_071320.2|refseq:NP_071505.2|ensembl:ENSG00000116001(gene)|ensembl:ENST00000433529(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034830|interpro:IPR034832|interpro:IPR035979|rcsb pdb:2MJN|rcsb pdb:3BS9|rcsb pdb:5ITH|rcsb pdb:5O2V|rcsb pdb:5O3J|rcsb pdb:6ELD|reactome:R-HSA-6803529|mint:P31483	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:d2ecwJo5sjSY6a/By3GM3B5A6PE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8IUF8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-751580|uniprotkb:Q6AHW4|uniprotkb:Q6SKS0|uniprotkb:Q8IU69|uniprotkb:Q8IUF6|uniprotkb:Q8IUF7|uniprotkb:Q96KB0|uniprotkb:Q96C17|uniprotkb:D3DN35|ensembl:ENSP00000328251|ensembl:ENSP00000377748	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:riox2_human(display_long)|uniprotkb:RIOX2(gene name)|psi-mi:RIOX2(display_short)|uniprotkb:60S ribosomal protein L27a histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA(gene name synonym)|uniprotkb:Histone lysine demethylase MINA(gene name synonym)|uniprotkb:MDIG(gene name synonym)|uniprotkb:MINA(gene name synonym)|uniprotkb:MINA53(gene name synonym)|uniprotkb:MYC-induced nuclear antigen(gene name synonym)|uniprotkb:Mineral dust-induced gene protein(gene name synonym)|uniprotkb:NO52(gene name synonym)|uniprotkb:Nucleolar protein 52(gene name synonym)|uniprotkb:Ribosomal oxygenase MINA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001035998.1|refseq:NP_116167.3|refseq:NP_694822.2|refseq:NP_001248758.1|refseq:XP_005247895.1|dip:DIP-28141N|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR039994|mint:Q8IUF8|rcsb pdb:2XDV|rcsb pdb:4BU2|rcsb pdb:4BXF|reactome:R-HSA-3214842|ensembl:ENSG00000170854(gene)|ensembl:ENST00000333396(transcript)|ensembl:ENST00000394198(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:tdjUsv9EuHn+AADASjfGu9U15Xc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P00374	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10039315|ensembl:ENSP00000396308|ensembl:ENSP00000426474|uniprotkb:B4DDD2|uniprotkb:Q14130|uniprotkb:Q6IRW8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dyr_human(display_long)|uniprotkb:DHFR(gene name)|psi-mi:DHFR(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000782.1|refseq:NP_001277283.1|ensembl:ENST00000439211(transcript)|ensembl:ENST00000505337(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004146"(dihydrofolate reductase activity)|go:"GO:0005542"(folic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006545"(glycine biosynthetic process)|go:"GO:0006729"(tetrahydrobiopterin biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031103"(axon regeneration)|go:"GO:0031427"(response to methotrexate)|go:"GO:0046452"(dihydrofolate metabolic process)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051870"(methotrexate binding)|rcsb pdb:4QHV|rcsb pdb:4QJC|rcsb pdb:5HPB|rcsb pdb:5HQY|rcsb pdb:5HQZ|rcsb pdb:5HSR|rcsb pdb:5HSU|rcsb pdb:5HT4|rcsb pdb:5HT5|rcsb pdb:5HUI|rcsb pdb:5HVB|rcsb pdb:5HVE|rcsb pdb:6A7C|rcsb pdb:6A7E|rcsb pdb:6DAV|rcsb pdb:6DE4|rcsb pdb:6VCJ|rcsb pdb:7ESE|reactome:R-HSA-1474151|reactome:R-HSA-196757|reactome:R-HSA-69205|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:2000121"(regulation of removal of superoxide radicals)|go:"GO:0070402"(NADPH binding)|interpro:IPR001796(Dihydrofolate reductase region)|interpro:IPR012259(Dihydrofolate reductase)|interpro:IPR017925|interpro:IPR024072|rcsb pdb:1BOZ|rcsb pdb:1DHF|rcsb pdb:1DLR|rcsb pdb:1DLS|rcsb pdb:1DRF|rcsb pdb:1HFP|rcsb pdb:1HFQ|rcsb pdb:1HFR|rcsb pdb:1KMS|rcsb pdb:1KMV|rcsb pdb:1MVS|rcsb pdb:1MVT|rcsb pdb:1OHJ|rcsb pdb:1OHK|rcsb pdb:1PD8|rcsb pdb:1PD9|rcsb pdb:1PDB|rcsb pdb:1S3U|rcsb pdb:1S3V|rcsb pdb:1S3W|rcsb pdb:1U71|rcsb pdb:1U72|rcsb pdb:1YHO|rcsb pdb:2C2S|rcsb pdb:2C2T|rcsb pdb:2DHF|rcsb pdb:2W3A|rcsb pdb:2W3B|rcsb pdb:2W3M|rcsb pdb:3EIG|rcsb pdb:3F8Y|rcsb pdb:3F8Z|rcsb pdb:3F91|rcsb pdb:3FS6|rcsb pdb:3GHC|rcsb pdb:3GHV|rcsb pdb:3GHW|ensembl:ENSG00000228716(gene)|rcsb pdb:3GI2|rcsb pdb:3GYF|rcsb pdb:3L3R|rcsb pdb:3N0H|rcsb pdb:3NTZ|rcsb pdb:3NU0|rcsb pdb:3NXO|rcsb pdb:3NXR|rcsb pdb:3NXT|rcsb pdb:3NXV|rcsb pdb:3NXX|rcsb pdb:3NXY|rcsb pdb:3NZD|rcsb pdb:3OAF|rcsb pdb:3S3V|rcsb pdb:3S7A|rcsb pdb:4DDR|rcsb pdb:4G95|rcsb pdb:4KAK|rcsb pdb:4KBN|rcsb pdb:4KD7|rcsb pdb:4KEB|rcsb pdb:4KFJ|rcsb pdb:4M6J|rcsb pdb:4M6K|rcsb pdb:4M6L	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4yoitO/ETpazAN2OtD/rXCte4289606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P56182	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z3C6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-727146|uniprotkb:Q6P0N7|uniprotkb:Q7Z317|uniprotkb:Q7Z320|uniprotkb:Q8NDK6|uniprotkb:Q8WU65|uniprotkb:Q9BVL5|uniprotkb:Q9H6L1|uniprotkb:Q9HAG7|uniprotkb:Q3ZAQ6|ensembl:ENSP00000355173|ensembl:ENSP00000379983|ensembl:ENSP00000386710	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:atg9a_human(display_long)|uniprotkb:APG9-like 1(gene name synonym)|uniprotkb:ATG9A(gene name)|psi-mi:ATG9A(display_short)|uniprotkb:APG9L1(gene name synonym)|uniprotkb:mATG9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001070666.1|refseq:NP_076990.4|ensembl:ENSG00000198925(gene)|ensembl:ENST00000361242(transcript)|ensembl:ENST00000396761(transcript)|ensembl:ENST00000409618(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|mint:Q7Z3C6|rcsb pdb:6WQZ|rcsb pdb:6WR4|rcsb pdb:7JLO|rcsb pdb:7JLP|rcsb pdb:7JLQ|reactome:R-HSA-1632852	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:arvq+TjXETr14g/FkOITnLfYVh89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:A0A0B4J233	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943446|ensembl:ENSP00000438083	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:a0a0b4j233_human(display_long)|uniprotkb:RBP5(gene name)|psi-mi:RBP5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000139194(gene)|ensembl:ENST00000542370(transcript)|go:"GO:0016918"(retinal binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|interpro:IPR031270	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DnioiXjvghFAJ2Y+UdSXPehX6q89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BV20	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-747381|uniprotkb:Q8NDC9|ensembl:ENSP00000040663	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mtna_human(display_long)|uniprotkb:UNQ6390/PRO21135(orf name)|uniprotkb:MRI1(gene name)|psi-mi:MRI1(display_short)|uniprotkb:S-methyl-5-thioribose-1-phosphate isomerase(gene name synonym)|uniprotkb:Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein(gene name synonym)|uniprotkb:MRDI(gene name synonym)|uniprotkb:Mediator of RhoA-dependent invasion(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001026897.1|refseq:NP_115661.1|ensembl:ENSG00000037757(gene)|ensembl:ENST00000040663(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019284"(L-methionine salvage from S-adenosylmethionine)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0046523"(S-methyl-5-thioribose-1-phosphate isomerase activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR005251(Putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase)|interpro:IPR011559(Initiation factor 2B alpha/beta/delta)|interpro:IPR027363|interpro:IPR037171|interpro:IPR042529|rcsb pdb:4LDQ|rcsb pdb:4LDR|reactome:R-HSA-1237112|refseq:NP_001316501.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bKds9iwCb1kJLHU69Dma3/6sj9o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92685	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15126	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1055562|uniprotkb:Q5TZW9|ensembl:ENSP00000357452	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pmvk_human(display_long)|uniprotkb:PMVK(gene name)|psi-mi:PMVK(display_short)|uniprotkb:PMKI(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006547.1|ensembl:ENSG00000163344(gene)|ensembl:ENST00000368467(transcript)|go:"GO:0004631"(phosphomevalonate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070723"(response to cholesterol)|interpro:IPR005919(Higher eukaryotic phosphomevalonate kinase)|interpro:IPR027417|mint:Q15126|rcsb pdb:3CH4|reactome:R-HSA-191273|reactome:R-HSA-2426168	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bDsF+xduPQB+HVXbNikncal5foo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14976	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-714707|uniprotkb:Q9BVY6|uniprotkb:Q5U4P5|intact:EBI-28970318|ensembl:ENSP00000314499	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gak_human(display_long)|uniprotkb:GAK(gene name)|psi-mi:GAK(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000314499|ensembl:ENST00000511163|ensembl:ENSP00000421361|refseq:NP_005246.2|refseq:NP_001305063.1|ensembl:ENSG00000178950(gene)|ensembl:ENST00000314167(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0030276"(clathrin binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031982"(vesicle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905224"(clathrin-coated pit assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014020(C2 tensin-type)|interpro:IPR029021|interpro:IPR029023|interpro:IPR035892|interpro:IPR036869|rcsb pdb:4C57|rcsb pdb:4C58|rcsb pdb:4C59|rcsb pdb:4O38|rcsb pdb:4Y8D|rcsb pdb:5Y7Z|rcsb pdb:5Y80|reactome:R-HSA-432722|reactome:R-HSA-8856828|go:"GO:0072318"(clathrin coat disassembly)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+CTVzAL9y1B3+JIg6PHsj8QXIjE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NZN8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-743033|uniprotkb:Q9H3E0|uniprotkb:Q9NSX5|uniprotkb:Q9NWR6|uniprotkb:Q9P028|ensembl:ENSP00000229195|ensembl:ENSP00000412091|ensembl:ENSP00000449260	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cnot2_human(display_long)|uniprotkb:CCR4-associated factor 2(gene name synonym)|uniprotkb:CNOT2(gene name)|psi-mi:CNOT2(display_short)|uniprotkb:CDC36(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:HSPC131(orf name)|uniprotkb:MSTP046(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186231.1|refseq:NP_001186232.1|refseq:XP_011536701.1|refseq:NP_055330.1|dip:DIP-42656N|reactome:R-HSA-429947|reactome:R-HSA-6804115|rcsb pdb:5FU7|ensembl:ENSG00000111596(gene)|ensembl:ENST00000229195(transcript)|ensembl:ENST00000418359(transcript)|ensembl:ENST00000551043(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001222"(transcription corepressor binding)|rcsb pdb:5FU6|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|mint:Q9NZN8|rcsb pdb:4C0D|rcsb pdb:4C0F	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:EuftUgW57O3LzzkQmgktP/V+eQk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5T5U3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1642518|uniprotkb:Q8NI19|uniprotkb:Q0VF98|uniprotkb:Q7Z3P7|uniprotkb:Q8N3A2|uniprotkb:Q8TBV5|uniprotkb:Q9P2C3|ensembl:ENSP00000379709	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rhg21_human(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 21(gene name synonym)|uniprotkb:Rho GTPase-activating protein 10(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_065875.3|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9013148|ensembl:ENSG00000107863(gene)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051645"(Golgi localization)|ensembl:ENST00000396432(transcript)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR000198(RhoGAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR041489|mint:Q5T5U3|rcsb pdb:2DHJ|rcsb pdb:2J59|rcsb pdb:2YUY|reactome:R-HSA-8980692|reactome:R-HSA-9013026|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9013106|refseq:XP_005252599.1|refseq:XP_016871948.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96PC5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1050253|uniprotkb:O00169|uniprotkb:Q6P2R8|uniprotkb:Q8IX92|uniprotkb:Q8IX93|uniprotkb:B3KRA6|uniprotkb:Q6MZN2|uniprotkb:Q86TF6|uniprotkb:D3DSA6|uniprotkb:B4DQS6|uniprotkb:G3XAC5|intact:EBI-28968219|ensembl:ENSP00000491014|uniprotkb:A0A193H6U5|uniprotkb:A1L4H0|uniprotkb:O15320|uniprotkb:Q9H6C1|intact:EBI-12051101	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mia2_human(display_long)|uniprotkb:MIA2(gene name)|psi-mi:MIA2(display_short)|uniprotkb:CTAGE family member 5 ER export factor(gene name synonym)|uniprotkb:CTAGE5(gene name synonym)|uniprotkb:MEA11(gene name synonym)|uniprotkb:MEA6(gene name synonym)|uniprotkb:MGEA11(gene name synonym)|uniprotkb:MGEA6(gene name synonym)|uniprotkb:Meningioma-expressed antigen 6/11(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000280082|ensembl:ENSP00000280082|ensembl:ENST00000280083|ensembl:ENSP00000280083|ensembl:ENST00000341502|ensembl:ENSP00000339286|ensembl:ENST00000341749|ensembl:ENSP00000343897|ensembl:ENST00000348007|ensembl:ENSP00000343912|ensembl:ENST00000396158|ensembl:ENSP00000379462|ensembl:ENST00000396165|ensembl:ENSP00000379468|ensembl:ENST00000553352|ensembl:ENSP00000450449|ensembl:ENST00000556148|ensembl:ENSP00000452562|ensembl:ENST00000557038|ensembl:ENSP00000450869|ensembl:ENSP00000491014|refseq:NP_001234917.1|refseq:NP_001234918.1|refseq:NP_001234919.1|refseq:NP_005921.2|refseq:NP_976231.1|refseq:XP_006720211.1|refseq:XP_011535086.1|refseq:XP_011535087.1|refseq:XP_016876809.1|refseq:XP_016876814.1|ensembl:ENSG00000150527(gene)|ensembl:ENST00000640607(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|interpro:IPR001452(Src homology-3)|interpro:IPR035555|interpro:IPR036028|reactome:R-HSA-5694530|refseq:NP_001316143.1|refseq:NP_473365.3|refseq:NP_976229.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:zQAma43vGRCJbRailTZAmAoKMxM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14657	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2564400|ensembl:ENSP00000259339	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tor1b_human(display_long)|uniprotkb:TOR1B(gene name)|psi-mi:TOR1B(display_short)|uniprotkb:DQ1(gene name synonym)|uniprotkb:Torsin family 1 member B(gene name synonym)|uniprotkb:FKSG18(orf name)|uniprotkb:Torsin ATPase-1B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055321.1|refseq:NP_001304822.1|refseq:NP_001304823.1|ensembl:ENSG00000136816(gene)|ensembl:ENST00000259339(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0019894"(kinesin binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR010448(Torsin)|interpro:IPR017378(Torsin, subgroup)|interpro:IPR027417|interpro:IPR030550|reactome:R-HSA-8856825|dip:DIP-56930N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fndSvHSKjI77izB7z7LdCyhmdbk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TB36	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11110431|uniprotkb:E7FJF4|uniprotkb:E7FJF3|uniprotkb:A8K957|ensembl:ENSP00000220822	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gdap1_human(display_long)|uniprotkb:GDAP1(gene name)|psi-mi:GDAP1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001035808.1|refseq:NP_061845.2|ensembl:ENSG00000104381(gene)|ensembl:ENST00000220822(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0071305"(cellular response to vitamin D)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034336|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|rcsb pdb:7AIA|rcsb pdb:7ALM|reactome:R-HSA-9603798	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:OrA2TaUsWoSfp/jX35NAkdILKek9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y314	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1051889|uniprotkb:Q96FD2|ensembl:ENSP00000470034	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nosip_human(display_long)|uniprotkb:eNOS-interacting protein(gene name synonym)|uniprotkb:NOSIP(gene name)|psi-mi:NOSIP(display_short)|uniprotkb:CGI-25(orf name)|uniprotkb:E3 ubiquitin-protein ligase NOSIP(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NOSIP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001257889.1|refseq:NP_057037.1|ensembl:ENSG00000142546(gene)|ensembl:ENST00000596358(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016818(Nitric oxide synthase-interacting)|interpro:IPR031790|reactome:R-HSA-203754|refseq:XP_016882340.1|refseq:XP_016882341.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:vC1sjYkWe4QjRlwCJ3C5+EB8PcA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NQ88	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3920747|ensembl:ENSP00000179259|uniprotkb:B2R840	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tigar_human(display_long)|uniprotkb:TIGAR(gene name)|psi-mi:TIGAR(display_short)|uniprotkb:C12orf5(gene name synonym)|uniprotkb:TP53-induced glycolysis and apoptosis regulator(gene name synonym)|uniprotkb:TP53-induced glycolysis regulatory phosphatase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000078237(gene)|ensembl:ENST00000179259(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004083"(bisphosphoglycerate 2-phosphatase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902153"(regulation of response to DNA damage checkpoint signaling)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|rcsb pdb:3DCY|reactome:R-HSA-5628897|refseq:NP_065108.1|dip:DIP-60093N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ffjUtBnwjatlJlNTmvrRTp1XtqU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HCM4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P13473	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2907154|uniprotkb:A8K4X5|uniprotkb:Q16641|uniprotkb:Q96J30|uniprotkb:Q99534|uniprotkb:Q9UD93|uniprotkb:D3DTF0|intact:EBI-4324646|uniprotkb:Q6Q3G8|ensembl:ENSP00000200639	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lamp2_human(display_long)|uniprotkb:LAMP2(gene name)|psi-mi:LAMP2(display_short)|uniprotkb:CD107 antigen-like family member B(gene name synonym)|uniprotkb:LGP-96(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002285.1|refseq:NP_054701.1|refseq:NP_001116078.1|ensembl:ENSG00000005893(gene)|ensembl:ENST00000200639(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0017038"(protein import)|go:"GO:0019899"(enzyme binding)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0044754"(autolysosome)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0061742"(chaperone-mediated autophagy translocation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097637"(integral component of autophagosome membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1990836"(lysosomal matrix)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P13473|rcsb pdb:2MOF|rcsb pdb:2MOM|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-9613829	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+s4K/qoL3PBwjATJmFDQtqcl/ZQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H4A3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-457907|uniprotkb:O15052|uniprotkb:P54963|uniprotkb:Q86WL5|uniprotkb:Q8N673|uniprotkb:Q9P1S9|uniprotkb:Q4VBX9|intact:EBI-948424|uniprotkb:A1L4B0|uniprotkb:Q6IFS5|uniprotkb:C5HTZ5|uniprotkb:C5HTZ6|uniprotkb:C5HTZ7|uniprotkb:H6WZW3|uniprotkb:Q96CZ6|ensembl:ENSP00000313059	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:wnk1_human(display_long)|uniprotkb:WNK1(gene name)|psi-mi:WNK1(display_short)|uniprotkb:KDP(gene name synonym)|uniprotkb:KIAA0344(gene name synonym)|uniprotkb:PRKWNK1(gene name synonym)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 1(gene name synonym)|uniprotkb:Erythrocyte 65 kDa protein(gene name synonym)|uniprotkb:Kinase deficient protein(gene name synonym)|uniprotkb:HSN2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000313059|ensembl:ENST00000340908|ensembl:ENSP00000341292|ensembl:ENST00000530271|ensembl:ENSP00000433548|ensembl:ENST00000537687|ensembl:ENSP00000444465|ensembl:ENST00000675631|ensembl:ENSP00000502415|refseq:NP_001171914.1|refseq:NP_055638.2|refseq:NP_061852.3|refseq:NP_998820.3|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1904062"(regulation of cation transmembrane transport)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|mint:Q9H4A3|rcsb pdb:4PWN|rcsb pdb:5TF9|rcsb pdb:5WDY|rcsb pdb:5WE8|rcsb pdb:6FBK|reactome:R-HSA-2672351|go:"GO:0097022"(lymphocyte migration into lymph node)|ensembl:ENSG00000060237(gene)|ensembl:ENST00000315939(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006811"(ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033633"(negative regulation of cell-cell adhesion mediated by integrin)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038116"("chemokine (C-C motif) ligand 21 signaling pathway")|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048666"(neuron development)|go:"GO:0050794"(regulation of cellular process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|refseq:XP_016875326.1|refseq:XP_016875327.1|dip:DIP-32648N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Jt4cvhSumyRRIZDmWgj4GsG7wjQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13190	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q86Y82	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2691717|uniprotkb:B1AJQ7|uniprotkb:O95564|ensembl:ENSP00000363054	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stx12_human(display_long)|uniprotkb:STX12(gene name)|psi-mi:STX12(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_803173.1|ensembl:ENSG00000117758(gene)|ensembl:ENST00000373943(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048278"(vesicle docking)|go:"GO:0050821"(protein stabilization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|mint:Q86Y82|rcsb pdb:2DNX|dip:DIP-44225N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:kSTOaE08HK8SpI19dBZRZbOVCGw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P45985	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-447868|uniprotkb:D3DTS5|uniprotkb:Q5U0B8|uniprotkb:B2R7N7|uniprotkb:B3KYB2|uniprotkb:Q6FHX4|uniprotkb:Q6P9H2|uniprotkb:Q6PIE6|intact:EBI-28973354|ensembl:ENSP00000262445	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mp2k4_human(display_long)|uniprotkb:JNK-activating kinase 1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase kinase 1(gene name synonym)|uniprotkb:SAPK/ERK kinase 1(gene name synonym)|uniprotkb:MAP2K4(gene name)|psi-mi:MAP2K4(display_short)|uniprotkb:JNKK1(gene name synonym)|uniprotkb:MKK4(gene name synonym)|uniprotkb:PRKMK4(gene name synonym)|uniprotkb:SERK1(gene name synonym)|uniprotkb:MEK4(gene name synonym)|uniprotkb:MAPK/ERK kinase 4(gene name synonym)|uniprotkb:SKK1(gene name synonym)|uniprotkb:SEK1(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003001.1|ensembl:ENSP00000262445|ensembl:ENST00000415385|ensembl:ENSP00000410402|refseq:NP_001268364.1|ensembl:ENST00000353533(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008545"(JUN kinase kinase activity)|go:"GO:0009611"(response to wounding)|go:"GO:0030424"(axon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072709"(cellular response to sorbitol)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000672"(negative regulation of motor neuron apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P45985|rcsb pdb:3ALN|rcsb pdb:3ALO|rcsb pdb:3VUT|reactome:R-HSA-2559580|reactome:R-HSA-2871796|reactome:R-HSA-450321|reactome:R-HSA-5210891|reactome:R-HSA-5684264|ensembl:ENSG00000065559(gene)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/ndhkIbnc9oTm68r4DwDUyfXDF89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UG56	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-721929|uniprotkb:O43207|uniprotkb:O95535|uniprotkb:Q6IC28|uniprotkb:Q96GQ2|uniprotkb:Q9UGA9|ensembl:ENSP00000391739|uniprotkb:B1AKM7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pisd_human(display_long)|uniprotkb:PISD(gene name)|psi-mi:PISD(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000241878(gene)|ensembl:ENST00000439502(transcript)|go:"GO:0004609"(phosphatidylserine decarboxylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|interpro:IPR003817(Phosphatidylserine decarboxylase-related)|interpro:IPR033177|interpro:IPR033661|reactome:R-HSA-1483213|refseq:NP_055153.1|refseq:NP_001313340.1|refseq:NP_001313344.1|refseq:NP_001313345.1|refseq:NP_001313346.1|refseq:NP_821141.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3X2aiRWVuM4Iow/j9SlUlMvuP2s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z460	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-913476|uniprotkb:B7ZLX3|uniprotkb:O75118|uniprotkb:Q2KHQ9|uniprotkb:Q5H9P0|uniprotkb:Q8N5B8|uniprotkb:Q9BQT5|ensembl:ENSP00000263710|intact:EBI-2562829|uniprotkb:A2RU21|uniprotkb:F5GWS0|intact:EBI-10967465	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:clap1_human(display_long)|uniprotkb:CLASP1(gene name)|psi-mi:CLASP1(display_short)|uniprotkb:KIAA0622(gene name synonym)|uniprotkb:MAST1(gene name synonym)|uniprotkb:Cytoplasmic linker-associated protein 1(gene name synonym)|uniprotkb:Multiple asters homolog 1(gene name synonym)|uniprotkb:Protein Orbit homolog 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001135745.1|refseq:NP_001135746.1|refseq:NP_001193980.1|refseq:NP_056097.1|ensembl:ENSG00000074054(gene)|ensembl:ENST00000263710(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031592"(centrosomal corona)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0043515"(kinetochore binding)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|refseq:XP_011509150.1|ensembl:ENSP00000263710|ensembl:ENST00000397587|ensembl:ENSP00000380717|ensembl:ENST00000409078|ensembl:ENSP00000386442|ensembl:ENST00000541377|ensembl:ENSP00000441625|interpro:IPR024395|interpro:IPR028399|interpro:IPR034085|rcsb pdb:4K92|rcsb pdb:6MQ5|rcsb pdb:6MQ7|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-428890|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ZhVWdhW2ylZHeewHZ63lg5FQT1c9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NRL3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-717245|intact:EBI-1058338|uniprotkb:Q8NE53|uniprotkb:A0A024R0V2|uniprotkb:B4DQH7|uniprotkb:F8VYA6|ensembl:ENSP00000263280	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:strn4_human(display_long)|uniprotkb:Zinedin(gene name synonym)|uniprotkb:STRN4(gene name)|psi-mi:STRN4(display_short)|uniprotkb:ZIN(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001034966.1|refseq:NP_037535.2|ensembl:ENSG00000090372(gene)|ensembl:ENST00000263280(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9NRL3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bgxVT2XfIqKPoGoN0sapQOnwfxw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92604	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6116942|uniprotkb:Q53YL2|ensembl:ENSP00000355963|ensembl:ENSP00000355964	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lgat1_human(display_long)|uniprotkb:LPGAT1(gene name)|psi-mi:LPGAT1(display_short)|uniprotkb:FAM34A(gene name synonym)|uniprotkb:KIAA0205(gene name synonym)|uniprotkb:"Acyl-CoA:monoacylglycerol acyltransferase LPGAT1"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011508530.1|refseq:XP_011508531.1|refseq:NP_001307737.1|refseq:NP_055688.1|ensembl:ENSG00000123684(gene)|ensembl:ENST00000366996(transcript)|ensembl:ENST00000366997(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0003846"(2-acylglycerol O-acyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0036148"(phosphatidylglycerol acyl-chain remodeling)|go:"GO:0036149"(phosphatidylinositol acyl-chain remodeling)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0047144"(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0071617"(lysophospholipid acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR032098|mint:Q92604|reactome:R-HSA-1482925	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9N2frmSoY9VESmi8Z3ERTo1L3CU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N1F8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2340204|uniprotkb:Q8NAW9|uniprotkb:Q96PY9|uniprotkb:Q8WXE4|uniprotkb:Q96CN3|uniprotkb:C9JQV3|ensembl:ENSP00000389383	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:s11ip_human(display_long)|uniprotkb:STK11IP(gene name)|psi-mi:STK11IP(display_short)|uniprotkb:KIAA1898(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:LKB1IP(gene name synonym)|uniprotkb:STK11IP1(gene name synonym)|uniprotkb:LKB1-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_443134.3|ensembl:ENSG00000144589(gene)|ensembl:ENST00000456909(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0008104"(protein localization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035578"(azurophil granule lumen)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR031782|interpro:IPR032675|mint:Q8N1F8|reactome:R-HSA-6798695	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bkZvSPFpB2rsgtmUrzt1YPiGrp49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TD19	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1044009|uniprotkb:Q52LK6|uniprotkb:Q8NCN0|uniprotkb:Q8TCY4|uniprotkb:Q9UPI4|uniprotkb:Q9Y6S4|uniprotkb:Q9Y6S5|uniprotkb:Q9Y6S6|intact:EBI-28978800|ensembl:ENSP00000238616	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nek9_human(display_long)|uniprotkb:NEK9(gene name)|psi-mi:NEK9(display_short)|uniprotkb:KIAA1995(gene name synonym)|uniprotkb:NEK8(gene name synonym)|uniprotkb:NERCC(gene name synonym)|uniprotkb:Never in mitosis A-related kinase 9(gene name synonym)|uniprotkb:Nercc1 kinase(gene name synonym)|uniprotkb:NimA-related kinase 8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_149107.4|ensembl:ENSG00000119638(gene)|ensembl:ENST00000238616(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR011009(Protein kinase-like)|interpro:IPR042767|mint:Q8TD19|rcsb pdb:3ZKE|rcsb pdb:3ZKF|reactome:R-HSA-2980767|reactome:R-HSA-3301854|reactome:R-HSA-9648025|ensembl:ENSP00000238616|refseq:NP_001316166.1|refseq:NP_001316167.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:nH92Hku490dDttw5Akug+NjXRNY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z6M4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-948435|ensembl:ENSP00000241527|ensembl:ENSP00000375840|ensembl:ENSP00000480378|uniprotkb:Q9P0E0|uniprotkb:A8K6K0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mtef4_human(display_long)|uniprotkb:Mitochondrial transcription termination factor 4(gene name synonym)|uniprotkb:mTERF domain-containing protein 2(gene name synonym)|uniprotkb:MTERF4(gene name)|psi-mi:MTERF4(display_short)|uniprotkb:MTERFD2(gene name synonym)|uniprotkb:HSPC096(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0007507"(heart development)|go:"GO:0019843"(rRNA binding)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043010"(camera-type eye development)|interpro:IPR003690(Mitochodrial transcription termination factor-related)|interpro:IPR038538|rcsb pdb:4FP9|rcsb pdb:4FZV|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF7|reactome:R-HSA-6793080|go:"GO:0006364"(rRNA processing)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006626"(protein targeting to mitochondrion)|ensembl:ENSG00000122085(gene)|ensembl:ENST00000241527(transcript)|ensembl:ENST00000391980(transcript)|ensembl:ENST00000614476(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|refseq:NP_872307.2|refseq:XP_016858876.1|dip:DIP-49918N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:hEwxLvLP6detYNELl7LYEVnThKA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N4T8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10897344|uniprotkb:Q8WTW8|uniprotkb:Q96K93|ensembl:ENSP00000303525	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cbr4_human(display_long)|uniprotkb:CBR4(gene name)|psi-mi:CBR4(display_short)|uniprotkb:SDR45C1(gene name synonym)|uniprotkb:Quinone reductase CBR4(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 45C member 1(gene name synonym)|uniprotkb:3-ketoacyl-[acyl-carrier-protein] reductase beta subunit(gene name synonym)|uniprotkb:Carbonyl reductase family member 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_116172.2|rcsb pdb:4CQL|rcsb pdb:4CQM|reactome:R-HSA-75105|interpro:IPR036291|ensembl:ENSG00000145439(gene)|ensembl:ENST00000306193(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008753"("NADPH dehydrogenase (quinone) activity")|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0048038"(quinone binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070402"(NADPH binding)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|go:"GO:1990204"(oxidoreductase complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:90umrT5u3VndeVMkAoOe8iewIJg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y371	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:HSs455W45ciZL56fJSPOIvfhUIw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8WVI0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943444|ensembl:ENSP00000417806	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:smim4_human(display_long)|uniprotkb:SMIM4(gene name)|psi-mi:SMIM4(display_short)|uniprotkb:C3orf78(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000168273(gene)|ensembl:ENST00000477703(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR028183|refseq:NP_001118239.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:HS9BNx35TCwOTWK6gXMTgf2gHVQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43813	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3046631|ensembl:ENSP00000233714|ensembl:ENSP00000388713|ensembl:ENSP00000393323|ensembl:ENSP00000393597|ensembl:ENSP00000397646	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lanc1_human(display_long)|uniprotkb:LANCL1(gene name)|psi-mi:LANCL1(display_short)|uniprotkb:GPR69A(gene name synonym)|uniprotkb:40 kDa erythrocyte membrane protein(gene name synonym)|uniprotkb:LanC-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000115365(gene)|ensembl:ENST00000233714(transcript)|ensembl:ENST00000431941(transcript)|ensembl:ENST00000441020(transcript)|ensembl:ENST00000443314(transcript)|ensembl:ENST00000450366(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043295"(glutathione binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:1903203"(regulation of oxidative stress-induced neuron death)|interpro:IPR007822(Lanthionine synthetase C-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR020464|mint:O43813|rcsb pdb:3E6U|rcsb pdb:3E73|refseq:NP_001130046.1|refseq:NP_001130047.1|refseq:NP_006046.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:em3J/MvBGB1LZ0X1QFagwWBk5FQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43617	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-743566|uniprotkb:B2RDN2|uniprotkb:D3DPS2|uniprotkb:A6NDN0|ensembl:ENSP00000362261	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tppc3_human(display_long)|uniprotkb:BET3 homolog(gene name synonym)|uniprotkb:TRAPPC3(gene name)|psi-mi:TRAPPC3(display_short)|uniprotkb:BET3(gene name synonym)|uniprotkb:CDABP0066(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055223.1|refseq:NP_001257823.1|refseq:NP_001257824.1|refseq:NP_001257825.1|refseq:NP_001257826.1|ensembl:ENSG00000054116(gene)|ensembl:ENST00000373166(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:O43617|rcsb pdb:1SZ7|rcsb pdb:2C0J|rcsb pdb:2CFH|rcsb pdb:3KXC|reactome:R-HSA-204005|reactome:R-HSA-8876198|dip:DIP-47627N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:YEQWfs0KIBIDkvJ+2Xtz8afsDCc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5SY16	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1055462|uniprotkb:Q4VBY3|uniprotkb:Q6P472|uniprotkb:Q7L4D6|uniprotkb:Q96EE0|uniprotkb:Q9H5L4|uniprotkb:Q2NL84|ensembl:ENSP00000366934	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nol9_human(display_long)|uniprotkb:NOL9(gene name)|psi-mi:NOL9(display_short)|uniprotkb:Nucleolar protein 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_078930.3|refseq:XP_011540449.1|ensembl:ENST00000377705(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051731"(polynucleotide 5'-hydroxyl-kinase activity)|interpro:IPR027417|interpro:IPR032319|mint:Q5SY16|reactome:R-HSA-6791226|ensembl:ENSG00000162408(gene)|refseq:XP_016857827.1|refseq:XP_016857828.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:IWGhuh/G+MlTxlSXEcIml8tvK7Y9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P84095	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-446579|uniprotkb:P35238|uniprotkb:Q8NI04|ensembl:ENSP00000339467|ensembl:ENSP00000380175|ensembl:ENSP00000380176|ensembl:ENSP00000436932	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rhog_human(display_long)|uniprotkb:RHOG(gene name)|psi-mi:RHOG(display_short)|uniprotkb:ARHG(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001656.2|refseq:XP_005252973.1|refseq:XP_016873208.1|ensembl:ENST00000396978(transcript)|ensembl:ENST00000396979(transcript)|ensembl:ENST00000533217(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|ensembl:ENSG00000177105(gene)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|ensembl:ENST00000351018(transcript)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR042734|mint:P84095|rcsb pdb:6UKA|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-5625970|reactome:R-HSA-6798695|reactome:R-HSA-6811558|reactome:R-HSA-9013408	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9PItVl1k5j6JhIDqwqcov1E/N8w9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15125	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3915253|uniprotkb:Q6IBI9|uniprotkb:Q6FGL3|ensembl:ENSP00000417052	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ebp_human(display_long)|uniprotkb:EBP(gene name)|psi-mi:EBP(display_short)|uniprotkb:Cholestenol Delta-isomerase(gene name synonym)|uniprotkb:"Delta(8)-Delta(7) sterol isomerase"(gene name synonym)|uniprotkb:Emopamil-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006570.1|ensembl:ENSG00000147155(gene)|ensembl:ENST00000495186(transcript)|go:"GO:0000247"(C-8 sterol isomerase activity)|go:"GO:0001501"(skeletal system development)|go:"GO:0004769"(steroid delta-isomerase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042802"(identical protein binding)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0047750"(cholestenol delta-isomerase activity)|interpro:IPR007905(Emopamil-binding)|interpro:IPR033118|rcsb pdb:6OHT|rcsb pdb:6OHU|reactome:R-HSA-6807047|reactome:R-HSA-6807062	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:7XfeeD/twqYll0Hv4YuJUbmAVJ09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q04721	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186930.1|refseq:NP_077719.2|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046849"(bone remodeling)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0072014"(proximal tubule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072104"(glomerular capillary formation)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:1990705"(cholangiocyte proliferation)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001204"(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0035622"(intrahepatic bile duct development)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022336|interpro:IPR010660(Notch, NOD region)|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|ensembl:ENSG00000134250(gene)|ensembl:ENST00000256646(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001947"(heart looping)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035264"(multicellular organism growth)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92506	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5461137|uniprotkb:A6NLX7|uniprotkb:Q5STP7|uniprotkb:Q9UIQ1|ensembl:ENSP00000230236|ensembl:ENSP00000363794|ensembl:ENSP00000387753|ensembl:ENSP00000403538|ensembl:ENSP00000406488|ensembl:ENSP00000413950	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dhb8_human(display_long)|uniprotkb:Estradiol 17-beta-dehydrogenase 8(gene name synonym)|uniprotkb:HSD17B8(gene name)|psi-mi:HSD17B8(display_short)|uniprotkb:FABGL(gene name synonym)|uniprotkb:HKE6(gene name synonym)|uniprotkb:RING2(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 8(gene name synonym)|uniprotkb:3-oxoacyl-[acyl-carrier-protein] reductase(gene name synonym)|uniprotkb:Protein Ke6(gene name synonym)|uniprotkb:Testosterone 17-beta-dehydrogenase 8(gene name synonym)|uniprotkb:SDR30C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 30C member 1(gene name synonym)|uniprotkb:3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055049.1|ensembl:ENSG00000112474(gene)|ensembl:ENSG00000204228(gene)|ensembl:ENSG00000225312(gene)|ensembl:ENSG00000228357(gene)|ensembl:ENSG00000228712(gene)|ensembl:ENSG00000232357(gene)|ensembl:ENST00000230236(transcript)|ensembl:ENST00000374662(transcript)|ensembl:ENST00000414463(transcript)|ensembl:ENST00000422433(transcript)|ensembl:ENST00000427295(transcript)|ensembl:ENST00000454191(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047025"("3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity")|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0048038"(quinone binding)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0070404"(NADH binding)|go:"GO:1990204"(oxidoreductase complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|go:"GO:0006703"(estrogen biosynthetic process)|rcsb pdb:2PD6|rcsb pdb:4CQL|rcsb pdb:4CQM|reactome:R-HSA-75105	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:jXKOiIp3Eh3Q/IHoLpkWQY0fjhs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q08379	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P86397	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943442|ensembl:ENSP00000481593|ensembl:ENSP00000482940|ensembl:ENSP00000484277	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:htd2_human(display_long)|uniprotkb:HTD2(gene name)|psi-mi:HTD2(display_short)|uniprotkb:3-hydroxyacyl-[acyl-carrier-protein] dehydratase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000255154(gene)|ensembl:ENST00000461393(transcript)|ensembl:ENST00000477305(transcript)|ensembl:ENST00000481972(transcript)|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|interpro:IPR002539(MaoC-like dehydratase)|interpro:IPR029069|rcsb pdb:3IR3|reactome:R-HSA-75105|refseq:NP_001335641.1|refseq:NP_001335642.1|refseq:NP_001335643.1|refseq:NP_001335644.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:yTBPrb6nnZySmE/bxtzjYTSaUb49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q4G176	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10714818|uniprotkb:A8K4J8|uniprotkb:C9JQL6|uniprotkb:Q6INA0|uniprotkb:Q8N2F7|ensembl:ENSP00000320646|ensembl:ENSP00000384627|ensembl:ENSP00000479130	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acsf3_human(display_long)|uniprotkb:ACSF3(gene name)|psi-mi:ACSF3(display_short)|uniprotkb:Acyl-CoA synthetase family member 3(gene name synonym)|uniprotkb:PSEC0197(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001120686.1|refseq:NP_001230208.1|refseq:NP_777577.2|ensembl:ENSG00000176715(gene)|ensembl:ENST00000317447(transcript)|ensembl:ENST00000406948(transcript)|ensembl:ENST00000614302(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0016405"(CoA-ligase activity)|go:"GO:0016878"(acid-thiol ligase activity)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0090409"(malonyl-CoA synthetase activity)|go:"GO:0090410"(malonate catabolic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|reactome:R-HSA-75876	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TSI6vfO7BHesTLbilpyoIeKy7oE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BSH4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-747797|uniprotkb:Q8N3N6|uniprotkb:Q9UI60|uniprotkb:B2RD21|ensembl:ENSP00000258975	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:taco1_human(display_long)|uniprotkb:PRO0477(orf name)|uniprotkb:TACO1(gene name)|psi-mi:TACO1(display_short)|uniprotkb:CCDC44(gene name synonym)|uniprotkb:Translational activator of mitochondrially-encoded cytochrome c oxidase I(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 44(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057444.2|ensembl:ENSG00000136463(gene)|ensembl:ENST00000258975(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0019843"(rRNA binding)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0061743"(motor learning)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR026564|interpro:IPR029072|mint:Q9BSH4|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:c/tu89NvCs3Kt8qO8e5F6hrywBo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NXR1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-941227|uniprotkb:Q49AQ2|ensembl:ENSP00000379642|ensembl:ENSP00000379643|ensembl:ENSP00000488050|ensembl:ENSP00000488199|ensembl:ENSP00000501936|ensembl:ENSP00000502160|ensembl:ENSP00000502354|ensembl:ENSP00000502635	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nde1_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short)|uniprotkb:NUDE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001137451.1|refseq:NP_060138.1|refseq:XP_016878838.1|refseq:XP_016878845.1|ensembl:ENSG00000072864(gene)|ensembl:ENSG00000275911(gene)|ensembl:ENST00000396354(transcript)|ensembl:ENST00000396355(transcript)|ensembl:ENST00000631844(transcript)|ensembl:ENST00000631923(transcript)|ensembl:ENST00000674554(transcript)|ensembl:ENST00000674888(transcript)|ensembl:ENST00000675926(transcript)|ensembl:ENST00000675951(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9NXR1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:H769EmQerGWsy6Zud3BBzkAuQw49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96P47	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6873422|uniprotkb:Q96RK3|uniprotkb:Q59EN0|uniprotkb:B3KNZ8|uniprotkb:E9PAL8|ensembl:ENSP00000480655	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:agap3_human(display_long)|uniprotkb:CENTG3(gene name synonym)|uniprotkb:CRAM-associated GTPase(gene name synonym)|uniprotkb:Centaurin-gamma-3(gene name synonym)|uniprotkb:MR1-interacting protein(gene name synonym)|uniprotkb:AGAP3(gene name)|psi-mi:AGAP3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001268229.1|refseq:XP_016867223.1|refseq:NP_114152.3|refseq:NP_001036000.1|ensembl:ENSG00000133612(gene)|ensembl:ENST00000622464(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071944"(cell periphery)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q96P47|rcsb pdb:3IHW	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:kfyXrwC5SFjflXEMQ2wfKoB98Ig9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q86TX2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11109648|uniprotkb:Q3I5F9|uniprotkb:A1L173|ensembl:ENSP00000311224	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acot1_human(display_long)|uniprotkb:ACOT1(gene name)|psi-mi:ACOT1(display_short)|uniprotkb:CTE-I(gene name synonym)|uniprotkb:CTE-Ib(gene name synonym)|uniprotkb:CTE1(gene name synonym)|uniprotkb:Inducible cytosolic acyl-coenzyme A thioester hydrolase(gene name synonym)|uniprotkb:Long chain acyl-CoA thioester hydrolase(gene name synonym)|uniprotkb:Palmitoyl-coenzyme A thioesterase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001032238.1|ensembl:ENSG00000184227(gene)|ensembl:ENST00000311148(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|interpro:IPR006862(Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase)|interpro:IPR014940(BAAT/Acyl-CoA thioester hydrolase C-terminal)|interpro:IPR016662(Acyl-CoA thioesterase, long chain)|interpro:IPR029058|interpro:IPR042490|reactome:R-HSA-77289	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:on1deS+8E4m2ZirUewH43L1VsPc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P04183	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-712550|ensembl:ENSP00000301634|uniprotkb:Q969V0|uniprotkb:Q9UMG9|uniprotkb:B2RC58	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kith_human(display_long)|uniprotkb:TK1(gene name)|psi-mi:TK1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000167900(gene)|ensembl:ENST00000301634(transcript)|go:"GO:0004797"(thymidine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046104"(thymidine metabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR001267(Thymidine kinase)|interpro:IPR020633|interpro:IPR027417|mint:P04183|rcsb pdb:1W4R|rcsb pdb:1XBT|rcsb pdb:2WVJ|reactome:R-HSA-69205|reactome:R-HSA-73614|rcsb pdb:2ORV|refseq:NP_003249.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:OzSF0TaoKwVaTna3Cu3HcogkZUc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P31937	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11427100|uniprotkb:Q546Z2|uniprotkb:Q9UDN3|ensembl:ENSP00000265395	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:3hidh_human(display_long)|uniprotkb:HIBADH(gene name)|psi-mi:HIBADH(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_689953.1|ensembl:ENSG00000106049(gene)|ensembl:ENST00000265395(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006574"(valine catabolic process)|go:"GO:0008442"(3-hydroxyisobutyrate dehydrogenase activity)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR002204(3-hydroxyisobutyrate dehydrogenase-related, conserved site)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011548(3-hydroxyisobutyrate dehydrogenase)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR015815(3-hydroxyacid dehydrogenase/reductase)|interpro:IPR029154|interpro:IPR036291|rcsb pdb:2GF2|rcsb pdb:2I9P|reactome:R-HSA-70895	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:YDYnI6BHB7iD3J2h+rR4GwFfrtg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6ZNB6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6117166|uniprotkb:B1Q2K1|uniprotkb:Q86VG1|uniprotkb:Q8WVH1|ensembl:ENSP00000333113|ensembl:ENSP00000370949|ensembl:ENSP00000422037	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nfxl1_human(display_long)|uniprotkb:NFXL1(gene name)|psi-mi:NFXL1(display_short)|uniprotkb:OZFP(gene name synonym)|uniprotkb:Ovarian zinc finger protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_694540.3|refseq:NP_001265552.1|refseq:NP_001265553.1|ensembl:ENSG00000170448(gene)|ensembl:ENST00000329043(transcript)|ensembl:ENST00000381538(transcript)|ensembl:ENST00000507489(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000967(Zinc finger, NF-X1-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR034078	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:IYD8+e0p5antDKQ2E+5N7UduDLQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N3R9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2513978|ensembl:ENSP00000261681|ensembl:ENSP00000503321|ensembl:ENSP00000503322|ensembl:ENSP00000503517|ensembl:ENSP00000503713|uniprotkb:Q86T98|uniprotkb:Q8N7I5|uniprotkb:Q7Z631|uniprotkb:Q9H9Q0|uniprotkb:A1L380	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pals1_human(display_long)|uniprotkb:PALS1(gene name)|psi-mi:PALS1(display_short)|uniprotkb:MAGUK p55 subfamily member 5(gene name synonym)|uniprotkb:MPP5(gene name synonym)|uniprotkb:Membrane protein, palmitoylated 5(gene name synonym)|uniprotkb:Protein associated with Lin-7 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010467"(gene expression)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032288"(myelin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035750"(protein localization to myelin sheath abaxonal region)|go:"GO:0043204"(perikaryon)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR015145(L27-N)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035601|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q8N3R9|rcsb pdb:1Y76|rcsb pdb:3UIT|rcsb pdb:4UU5|rcsb pdb:4UU6|rcsb pdb:4WSI|rcsb pdb:7M4R|rcsb pdb:7NTJ|rcsb pdb:7NTK|reactome:R-HSA-420029|ensembl:ENSG00000072415(gene)|ensembl:ENST00000261681(transcript)|ensembl:ENST00000676464(transcript)|ensembl:ENST00000677382(transcript)|ensembl:ENST00000677835(transcript)|ensembl:ENST00000678380(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|refseq:XP_011535388.1|refseq:XP_011535389.1|refseq:NP_071919.2|refseq:NP_001243479.1|refseq:XP_005268060.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VpQVKlVcuBSs8mztUd9iHqkIXDM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P55039	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-750565|uniprotkb:Q9BWB2|uniprotkb:B2R8G5|uniprotkb:Q53Y50|ensembl:ENSP00000225729	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:drg2_human(display_long)|uniprotkb:DRG2(gene name)|psi-mi:DRG2(display_short)|uniprotkb:Translation factor GTPase DRG2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001379.1|ensembl:ENSG00000108591(gene)|ensembl:ENST00000225729(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|interpro:IPR012676(TGS-like)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9bgX8C0kJmO5KdaYHU+vAmDCTPo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NP92	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6393499|ensembl:ENSP00000424328|uniprotkb:Q96I91|uniprotkb:Q96Q19|uniprotkb:Q9H0P8|uniprotkb:Q9NSF9|uniprotkb:Q9NZ76	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rt30_human(display_long)|uniprotkb:MRPS30(gene name)|psi-mi:MRPS30(display_short)|uniprotkb:PDCD9(gene name synonym)|uniprotkb:Programmed cell death protein 9(gene name synonym)|uniprotkb:BM-047(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein mS30(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000112996(gene)|ensembl:ENST00000507110(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|interpro:IPR010793(Ribosomal protein S30, mitochondrial)|interpro:IPR039982|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_057724.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:AyFqyCMR1Poix/xU7k195b8D+hw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HB40	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943440|uniprotkb:Q96A94|uniprotkb:Q9H3F0|ensembl:ENSP00000262288	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:risc_human(display_long)|uniprotkb:SCPEP1(gene name)|psi-mi:SCPEP1(display_short)|uniprotkb:RISC(gene name synonym)|uniprotkb:SCP1(gene name synonym)|uniprotkb:Serine carboxypeptidase 1(gene name synonym)|uniprotkb:MSTP034(orf name)|uniprotkb:UNQ265/PRO302(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_067639.1|ensembl:ENSG00000121064(gene)|ensembl:ENST00000262288(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0042573"(retinoic acid metabolic process)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097746"(blood vessel diameter maintenance)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FMuffJ/BPZAqjTvAjmwOPNQjWrY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P39060	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-981314|uniprotkb:Q58EX6|uniprotkb:Q6RZ39|uniprotkb:Q6RZ40|uniprotkb:Q6RZ41|uniprotkb:Q8N4S4|uniprotkb:Q8WXI5|uniprotkb:Q96T70|uniprotkb:Q9UK38|uniprotkb:Q9Y6Q7|uniprotkb:A8MVI4|ensembl:ENSP00000352798|uniprotkb:Q9Y6Q8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:coia1_human(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_085059.2|refseq:NP_569712.2|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR020067|interpro:IPR035523|interpro:IPR036790|rcsb pdb:1BNL|rcsb pdb:3HON|rcsb pdb:3HSH|reactome:R-HSA-1442490|reactome:R-HSA-1592389|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-8948216|ensembl:ENSG00000182871(gene)|ensembl:ENST00000359759(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007601"(visual perception)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR010363(Protein of unknown function DUF959, collagen XVIII, N-terminal)|interpro:IPR010515(Collagenase NC10 and endostatin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_569711.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:wLRIpnIxV06w/L+TD0ZldrjEsVs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O60831	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q969V5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-744120|uniprotkb:Q7Z431|uniprotkb:Q9H9B5|uniprotkb:B5M497|ensembl:ENSP00000264198	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mul1_human(display_long)|uniprotkb:C1orf166(gene name synonym)|uniprotkb:MAPL(gene name synonym)|uniprotkb:MULAN(gene name synonym)|uniprotkb:RNF218(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase MUL1(gene name synonym)|uniprotkb:GIDE(gene name synonym)|uniprotkb:Mitochondrial-anchored protein ligase(gene name synonym)|uniprotkb:RING finger protein 218(gene name synonym)|uniprotkb:MUL1(gene name)|psi-mi:MUL1(display_short)|uniprotkb:Growth inhibition and death E3 ligase(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 266(gene name synonym)|uniprotkb:E3 SUMO-protein ligase MUL1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NFKB 1(gene name synonym)|uniprotkb:Protein Hades(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_078820.2|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050821"(protein stabilization)|ensembl:ENST00000264198(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0002039"(p53 binding)|ensembl:ENSG00000090432(gene)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:1901028"(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR022170|mint:Q969V5|rcsb pdb:6K2K|go:"GO:0051898"(negative regulation of protein kinase B signaling)|rcsb pdb:6M2C|rcsb pdb:6M2D|reactome:R-HSA-5689880|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0051646"(mitochondrion localization)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:THGOIEcH68uAtym/UHsPpBYSbMA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UKA4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1049491|uniprotkb:O75124|uniprotkb:Q9NUK7|ensembl:ENSP00000025301	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:aka11_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 11(gene name synonym)|uniprotkb:A-kinase anchor protein 220 kDa(gene name synonym)|uniprotkb:AKAP11(gene name)|psi-mi:AKAP11(display_short)|uniprotkb:AKAP220(gene name synonym)|uniprotkb:KIAA0629(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011533205.1|refseq:XP_011533206.1|refseq:XP_011533207.1|refseq:XP_011533208.1|refseq:NP_057332.1|refseq:XP_016875870.1|ensembl:ENSG00000023516(gene)|ensembl:ENST00000025301(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR008382(A-kinase anchor 110 kDa)|mint:Q9UKA4	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:EoQOZuPirXCY2k5migb2Fr6utZ09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13425	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:SABgmvArdLH93OpFobs/L3BleVY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NTG7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-724621|uniprotkb:Q9Y6E8|ensembl:ENSP00000372191|uniprotkb:B7Z5U6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sir3_human(display_long)|uniprotkb:SIRT3(gene name)|psi-mi:SIRT3(display_short)|uniprotkb:SIR2L3(gene name synonym)|uniprotkb:SIR2-like protein 3(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001017524.1|refseq:NP_036371.1|ensembl:ENSG00000142082(gene)|ensembl:ENST00000382743(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009060"(aerobic respiration)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070403"(NAD+ binding)|go:"GO:1901671"(positive regulation of superoxide dismutase activity)|go:"GO:1902553"(positive regulation of catalase activity)|go:"GO:2000304"(positive regulation of ceramide biosynthetic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|go:"GO:0043565"(sequence-specific DNA binding)|rcsb pdb:3GLR|rcsb pdb:3GLS|rcsb pdb:3GLT|rcsb pdb:3GLU|rcsb pdb:4BN4|rcsb pdb:4BN5|rcsb pdb:4BV3|rcsb pdb:4BVB|rcsb pdb:4BVF|rcsb pdb:4BVG|rcsb pdb:4BVH|rcsb pdb:4C78|rcsb pdb:4C7B|rcsb pdb:4FVT|rcsb pdb:4FZ3|rcsb pdb:4HD8|rcsb pdb:4JSR|rcsb pdb:4JT8|rcsb pdb:4JT9|rcsb pdb:4O8Z|rcsb pdb:5BWN|rcsb pdb:5BWO|rcsb pdb:5D7N|rcsb pdb:5H4D|rcsb pdb:5Y4H|rcsb pdb:5YTK|rcsb pdb:5Z93|rcsb pdb:5Z94|rcsb pdb:5ZGC|rcsb pdb:6ISO|reactome:R-HSA-2151201|reactome:R-HSA-9615017|reactome:R-HSA-9617629|rcsb pdb:4BVE|refseq:XP_016872919.1|dip:DIP-46861N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:KGNwfCABi61filBQeIU5v5n51kE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H974	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1221028|uniprotkb:Q6IA59|uniprotkb:A6NGE9|uniprotkb:B7Z472|uniprotkb:B7Z5R2|uniprotkb:J3KR78|ensembl:ENSP00000281273	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:qtrt2_human(display_long)|uniprotkb:Queuine tRNA-ribosyltransferase domain-containing protein 1(gene name synonym)|uniprotkb:QTRT2(gene name)|psi-mi:QTRT2(display_short)|uniprotkb:QTRTD1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_078914.1|refseq:NP_001243764.1|refseq:NP_001243765.1|refseq:NP_001243766.1|refseq:XP_005247827.1|refseq:XP_016862671.1|refseq:XP_016862672.1|ensembl:ENSG00000151576(gene)|ensembl:ENST00000281273(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008479"(queuine tRNA-ribosyltransferase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0101030"(tRNA-guanine transglycosylation)|interpro:IPR002616(Queuine/other tRNA-ribosyltransferase)|interpro:IPR028592|interpro:IPR036511|reactome:R-HSA-6782315	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8OQIoDPH8P/UdGe3VQO9/4KdpFs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P48507	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1051387|uniprotkb:Q6FHC1|uniprotkb:Q9NPX9|uniprotkb:Q9NU74|uniprotkb:A8K334|uniprotkb:M5A959|uniprotkb:D3DT45|ensembl:ENSP00000359258	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gsh0_human(display_long)|uniprotkb:Gamma-glutamylcysteine synthetase regulatory subunit(gene name synonym)|uniprotkb:Gamma-ECS regulatory subunit(gene name synonym)|uniprotkb:GCS light chain(gene name synonym)|uniprotkb:Glutamate--cysteine ligase modifier subunit(gene name synonym)|uniprotkb:GCLM(gene name)|psi-mi:GCLM(display_short)|uniprotkb:GLCLR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002052.1|refseq:NP_001295182.1|ensembl:ENSG00000023909(gene)|ensembl:ENST00000370238(transcript)|go:"GO:0004357"(glutamate-cysteine ligase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006534"(cysteine metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0014823"(response to activity)|go:"GO:0017109"(glutamate-cysteine ligase complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035226"(glutamate-cysteine ligase catalytic subunit binding)|go:"GO:0035229"(positive regulation of glutamate-cysteine ligase activity)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0042493"|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0097069"(cellular response to thyroxine stimulus)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR023210|interpro:IPR032963|interpro:IPR036812|reactome:R-HSA-174403|reactome:R-HSA-5578999	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:arU12Xm86K7yRxElliA31V7z5d89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96JG6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11044388|uniprotkb:F5H5U7|uniprotkb:Q75N07|uniprotkb:Q8WVK3|uniprotkb:D1MQ00|uniprotkb:Q9H5C6|uniprotkb:B3KX22|ensembl:ENSP00000307666	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:vps50_human(display_long)|uniprotkb:VPS50(gene name)|psi-mi:VPS50(display_short)|uniprotkb:CCDC132(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 132(gene name synonym)|uniprotkb:EARP/GARPII complex subunit VPS50(gene name synonym)|uniprotkb:KIAA1861(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001244927.1|refseq:NP_060137.2|refseq:NP_078829.1|ensembl:ENSG00000004766(gene)|ensembl:ENST00000305866(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990745"(EARP complex)|interpro:IPR019514|interpro:IPR019515|interpro:IPR040047|dip:DIP-61628N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:P02U04G3Q2pPgmjDfcffuVJe6Z09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P60604	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BVK6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1056827|uniprotkb:Q8WZ61|uniprotkb:Q14437|ensembl:ENSP00000330945	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tmed9_human(display_long)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short)|uniprotkb:GP25L2(gene name synonym)|uniprotkb:Glycoprotein 25L2(gene name synonym)|uniprotkb:p25(gene name synonym)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:GMP25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_059980.2|ensembl:ENSG00000184840(gene)|ensembl:ENST00000332598(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9BVK6|reactome:R-HSA-6807878|reactome:R-HSA-6811434	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:z5YDyY6mtnc4WGWU9G9sNgp+Ga09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9ULC4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-716076|intact:EBI-1048747|uniprotkb:Q502X6|uniprotkb:B4DGY2|ensembl:ENSP00000360367|ensembl:ENSP00000500508	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mcts1_human(display_long)|uniprotkb:MCTS1(gene name)|psi-mi:MCTS1(display_short)|uniprotkb:MCT1(gene name synonym)|uniprotkb:Multiple copies T-cell malignancies(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001131026.1|refseq:NP_054779.1|ensembl:ENSG00000232119(gene)|ensembl:ENSG00000288295(gene)|ensembl:ENST00000371317(transcript)|ensembl:ENST00000673335(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0040008"(regulation of growth)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002478(PUA)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR015947(PUA-like)|interpro:IPR016437(Translation machinery-associated RNA binding protein, predicted)|interpro:IPR041366|rcsb pdb:3R90|rcsb pdb:5ONS|rcsb pdb:5VYC|rcsb pdb:6MS4	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:g630bQeYIEobBeB8zTPwIiGlPys9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y613	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-348433|ensembl:ENSP00000258201|uniprotkb:Q59F76|uniprotkb:Q6Y1F2|uniprotkb:Q76MS8|uniprotkb:Q8N521	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:fhod1_human(display_long)|uniprotkb:FHOD1(gene name)|psi-mi:FHOD1(display_short)|uniprotkb:FHOS(gene name synonym)|uniprotkb:FHOS1(gene name synonym)|uniprotkb:Formin homolog overexpressed in spleen 1(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_037373.2|ensembl:ENSG00000135723(gene)|ensembl:ENST00000258201(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007097"(nuclear migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051015"(actin filament binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0051660"(establishment of centrosome localization)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027647|interpro:IPR041387|interpro:IPR042201|rcsb pdb:3DAD|rcsb pdb:6XF1|rcsb pdb:6XF2|mint:Q9Y613|dip:DIP-31134N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8zGurHJ5FL9gvqZazyRAHElMAdI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00506	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-618295|ensembl:ENSP00000325748|ensembl:ENSP00000384162|ensembl:ENSP00000385687|uniprotkb:Q15522|uniprotkb:Q5BJF1|uniprotkb:A8K7D2|intact:EBI-5773834|uniprotkb:A8K6Z3|uniprotkb:B7Z9K1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stk25_human(display_long)|uniprotkb:STK25(gene name)|psi-mi:STK25(display_short)|uniprotkb:SOK1(gene name synonym)|uniprotkb:YSK1(gene name synonym)|uniprotkb:Sterile 20/oxidant stress-response kinase 1(gene name synonym)|uniprotkb:Ste20-like kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000115694(gene)|ensembl:ENST00000316586(transcript)|ensembl:ENST00000401869(transcript)|ensembl:ENST00000403346(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036481"(intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051645"(Golgi localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035060|rcsb pdb:2XIK|rcsb pdb:3W8H|rcsb pdb:4NZW|refseq:NP_006365.2|refseq:NP_001258908.1|refseq:NP_001258909.1|refseq:NP_001269234.1|refseq:NP_001269237.1|refseq:NP_001269236.1|refseq:NP_001258906.1|refseq:NP_001258907.1|dip:DIP-34269N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:yg5mghaePpT2LrC7wdG7xSGe0Pw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14773	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P19174	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-79387|uniprotkb:Q2V575|uniprotkb:B9EGH4|uniprotkb:B7ZLY7|uniprotkb:E1P5W4|intact:EBI-3959906|ensembl:ENSP00000362368	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:plcg1_human(display_long)|uniprotkb:PLC-148(gene name synonym)|uniprotkb:PLC1(gene name synonym)|uniprotkb:Phospholipase C-II(gene name synonym)|uniprotkb:PLCG1(gene name)|psi-mi:PLCG1(display_short)|uniprotkb:Phosphoinositide phospholipase C-gamma-1(gene name synonym)|uniprotkb:Phospholipase C-gamma-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002651.2|refseq:NP_877963.1|dip:DIP-100N|ensembl:ENSG00000124181(gene)|ensembl:ENST00000373271(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0050429"(calcium-dependent phospholipase C activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR000980(SH2 motif)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001452(Src homology-3)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016279(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma)|interpro:IPR017946|interpro:IPR018247|interpro:IPR028380|interpro:IPR035023|interpro:IPR035024|interpro:IPR035724|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|mint:P19174|rcsb pdb:1HSQ|rcsb pdb:2HSP|rcsb pdb:4EY0|rcsb pdb:4FBN|rcsb pdb:7NXE|reactome:R-HSA-1169408|reactome:R-HSA-1236382|reactome:R-HSA-1251932|reactome:R-HSA-1489509|reactome:R-HSA-167021|reactome:R-HSA-1855204|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029485|reactome:R-HSA-210990|reactome:R-HSA-212718|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-418890|reactome:R-HSA-5218921|reactome:R-HSA-5637810|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9026527|reactome:R-HSA-9027277|reactome:R-HSA-9034793|reactome:R-HSA-9664323|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:pJsNLrqg3cUj0SdjoyLf+/91yBo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y2Q3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1053767|uniprotkb:Q7Z520|uniprotkb:Q6P4H0|uniprotkb:Q9P1S4|uniprotkb:B4DIH1|uniprotkb:B4DSY2|ensembl:ENSP00000351181	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gstk1_human(display_long)|uniprotkb:Glutathione S-transferase subunit 13(gene name synonym)|uniprotkb:GST 13-13(gene name synonym)|uniprotkb:GST class-kappa(gene name synonym)|uniprotkb:GSTK1-1(gene name synonym)|uniprotkb:GSTK1(gene name)|psi-mi:GSTK1(display_short)|uniprotkb:HDCMD47P(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001137151.1|refseq:NP_001137152.1|refseq:NP_001137153.1|refseq:NP_057001.1|ensembl:ENSG00000197448(gene)|ensembl:ENST00000358406(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001853(DSBA oxidoreductase)|interpro:IPR014440(HCCA isomerase/glutathione S-transferase kappa)|interpro:IPR036249|interpro:IPR044088|rcsb pdb:1YZX|rcsb pdb:3RPN|rcsb pdb:3RPP|reactome:R-HSA-156590|reactome:R-HSA-9033241|dip:DIP-46924N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:aTjqqss32Y4bcsXg6gYlazahVCw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P15289	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2117357|uniprotkb:Q6ICI5|uniprotkb:Q96CJ0|uniprotkb:B2RCA6|uniprotkb:F8WCC8|uniprotkb:B7XD04	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:arsa_human(display_long)|uniprotkb:ARSA(gene name)|psi-mi:ARSA(display_short)|uniprotkb:Cerebroside-sulfatase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000478.3|refseq:NP_001078894.2|refseq:NP_001078895.2|refseq:NP_001078896.2|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR000917(Sulphatase)|interpro:IPR024607|rcsb pdb:1AUK|rcsb pdb:1E1Z|rcsb pdb:1E2S|rcsb pdb:1E33|rcsb pdb:1E3C|rcsb pdb:1N2K|rcsb pdb:1N2L|rcsb pdb:2AIJ|rcsb pdb:2AIK|refseq:XP_011528992.1|rcsb pdb:2HI8|reactome:R-HSA-1660662|reactome:R-HSA-1663150|refseq:NP_001078897.1|reactome:R-HSA-6798695|go:"GO:0004065"(arylsulfatase activity)|go:"GO:0004098"(cerebroside-sulfatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0008484"(sulfuric ester hydrolase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0070062"(extracellular exosome)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:r9aHZqERfWNUy9m6C0DG2pCtsEs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95905	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2557598|ensembl:ENSP00000362070|uniprotkb:C9JX46|uniprotkb:E9PAW8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ecd_human(display_long)|uniprotkb:Human suppressor of GCR two(gene name synonym)|uniprotkb:ECD(gene name)|psi-mi:ECD(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001129225.1|refseq:NP_009196.1|ensembl:ENSG00000122882(gene)|ensembl:ENST00000372979(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR010770(SGT1)|refseq:NP_001129224.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:7uvREpWu7KW0cAo8zcf7SSkaQiY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NUJ1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2564608|uniprotkb:B7Z6A8|uniprotkb:C9IZX5|uniprotkb:Q8TCF9|uniprotkb:D3DN63|ensembl:ENSP00000273359	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:abhda_human(display_long)|uniprotkb:ABHD10(gene name)|psi-mi:ABHD10(display_short)|uniprotkb:Alpha/beta hydrolase domain-containing protein 10(gene name synonym)|uniprotkb:Acyl-protein thioesterase ABHD10(gene name synonym)|uniprotkb:Mycophenolic acid acyl-glucuronide esterase, mitochondrial(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060864.1|refseq:XP_011511262.1|ensembl:ENSG00000144827(gene)|ensembl:ENST00000273359(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0019391"(glucuronoside catabolic process)|go:"GO:0052695"(cellular glucuronidation)|go:"GO:0102390"(mycophenolic acid acyl-glucuronide esterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|reactome:R-HSA-156588|refseq:NP_001258998.1|dip:DIP-56934N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ITjY8Sa8podE2/vmKMuwVmnTe+E9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P21953	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1029067|uniprotkb:Q5T2J3|ensembl:ENSP00000318351|ensembl:ENSP00000348880|uniprotkb:Q9BQL0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:odbb_human(display_long)|uniprotkb:BCKDHB(gene name)|psi-mi:BCKDHB(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component beta chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000047.1|refseq:NP_898871.1|ensembl:ENST00000356489(transcript)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0007584"(response to nutrient)|go:"GO:0009083"(branched-chain amino acid catabolic process)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR029061|interpro:IPR033248|rcsb pdb:1DTW|rcsb pdb:1OLS|rcsb pdb:1OLU|rcsb pdb:1OLX|rcsb pdb:1U5B|rcsb pdb:1V11|rcsb pdb:1V16|rcsb pdb:1V1M|rcsb pdb:1V1R|rcsb pdb:1WCI|rcsb pdb:1X7W|rcsb pdb:1X7X|rcsb pdb:1X7Y|rcsb pdb:1X7Z|rcsb pdb:1X80|rcsb pdb:2BEU|rcsb pdb:2BEV|rcsb pdb:2BEW|rcsb pdb:2BFB|rcsb pdb:2BFC|rcsb pdb:2BFD|rcsb pdb:2BFE|rcsb pdb:2BFF|rcsb pdb:2J9F|reactome:R-HSA-389661|reactome:R-HSA-70895|ensembl:ENSG00000083123(gene)|ensembl:ENST00000320393(transcript)|refseq:NP_001305904.1|dip:DIP-6147N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:2KgCDcF9/M5ZI8/2WV4bU1Qmnvk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NAN2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943438|uniprotkb:Q6MZG0|ensembl:ENSP00000359827|ensembl:ENSP00000495281	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:miga1_human(display_long)|uniprotkb:MIGA1(gene name)|psi-mi:MIGA1(display_short)|uniprotkb:FAM73A(gene name synonym)|uniprotkb:Protein FAM73A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001257313.1|refseq:NP_940951.1|ensembl:ENSG00000180488(gene)|ensembl:ENST00000370791(transcript)|ensembl:ENST00000643143(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR019392|mint:Q8NAN2|reactome:R-HSA-1483166	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ZIDtgENE8en73tFnADIVIal9wcg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BRX8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4399402|uniprotkb:B2RD81|uniprotkb:Q6UW08|uniprotkb:Q8N2K3|uniprotkb:Q8NBK9|uniprotkb:Q96JR0|ensembl:ENSP00000361254|ensembl:ENSP00000361261|ensembl:ENSP00000361262|ensembl:ENSP00000478152|ensembl:ENSP00000482445	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pxl2a_human(display_long)|uniprotkb:C10orf58(gene name synonym)|uniprotkb:PAMM(gene name synonym)|uniprotkb:Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes(gene name synonym)|uniprotkb:PRXL2A(gene name)|psi-mi:PRXL2A(display_short)|uniprotkb:FAM213A(gene name synonym)|uniprotkb:Redox-regulatory protein FAM213A(gene name synonym)|uniprotkb:PRO2290(orf name)|uniprotkb:PSEC0139(orf name)|uniprotkb:UNQ611/PRO1198(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_115709.3|refseq:NP_001230707.1|refseq:NP_001230708.1|refseq:NP_001230709.1|refseq:NP_001230710.1|refseq:XP_011538567.1|refseq:XP_011538568.1|refseq:NP_001230711.1|ensembl:ENSG00000122378(gene)|ensembl:ENST00000372181(transcript)|ensembl:ENST00000372187(transcript)|ensembl:ENST00000372188(transcript)|ensembl:ENST00000606162(transcript)|ensembl:ENST00000615554(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0016209"(antioxidant activity)|go:"GO:0045670"(regulation of osteoclast differentiation)|interpro:IPR032801|interpro:IPR032802|mint:Q9BRX8	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qAvv/5+5HfPHe6kqNCdbmDQvvMw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UMX0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-741480|uniprotkb:Q8IXS9|uniprotkb:Q8N2Q3|uniprotkb:Q9H0T8|uniprotkb:Q9H3R4|uniprotkb:Q9HAZ5|intact:EBI-28967608|ensembl:ENSP00000365576|uniprotkb:Q5T6J5|uniprotkb:Q5T6J9|uniprotkb:A0A024R284	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ubql1_human(display_long)|uniprotkb:Protein linking IAP with cytoskeleton 1(gene name synonym)|uniprotkb:UBQLN1(gene name)|psi-mi:UBQLN1(display_short)|uniprotkb:DA41(gene name synonym)|uniprotkb:PLIC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000257468|ensembl:ENSP00000257468|ensembl:ENSP00000365576|ensembl:ENSG00000135018(gene)|ensembl:ENST00000376395(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000502"(proteasome complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0019900"(kinase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035973"(aggrephagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1901340"(negative regulation of store-operated calcium channel activity)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028430|interpro:IPR029071|mint:Q9UMX0|rcsb pdb:2JY5|rcsb pdb:2JY6|rcsb pdb:2KLC|reactome:R-HSA-8856825|refseq:NP_038466.2|refseq:NP_444295.1|dip:DIP-41629N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:nCFfZbGCTvRYaXhQ4R99XblslvM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P51570	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43488	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-748855|uniprotkb:O75749|uniprotkb:Q5TG63|ensembl:ENSP00000235835	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ark72_human(display_long)|uniprotkb:AFB1 aldehyde reductase 1(gene name synonym)|uniprotkb:Aldoketoreductase 7(gene name synonym)|uniprotkb:AKR7A2(gene name)|psi-mi:AKR7A2(display_short)|uniprotkb:AFAR(gene name synonym)|uniprotkb:AFAR1(gene name synonym)|uniprotkb:AKR7(gene name synonym)|uniprotkb:Succinic semialdehyde reductase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003680.2|ensembl:ENSG00000053371(gene)|ensembl:ENST00000235835(transcript)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0019119"(phenanthrene-9,10-epoxide hydrolase activity)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR023210|interpro:IPR036812|rcsb pdb:2BP1|reactome:R-HSA-5423646	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:HUJHFlZOl/Xb03VzAZAcmsEHK9o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96C36	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358366|uniprotkb:Q7Z515|uniprotkb:Q9Y5J4|ensembl:ENSP00000342502|uniprotkb:A8K798	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:p5cr2_human(display_long)|uniprotkb:PYCR2(gene name)|psi-mi:PYCR2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_037460.2|ensembl:ENSG00000143811(gene)|ensembl:ENST00000343818(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:Q96C36|rcsb pdb:6LHM|reactome:R-HSA-8964539|refseq:NP_001258610.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:lIjn88RdpxuNpN+fgVPZV2bjubA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z4Q2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1051903|uniprotkb:Q8N525|uniprotkb:Q8WV56|uniprotkb:Q96CC9|uniprotkb:Q9NWN7|uniprotkb:A8K1N4|ensembl:ENSP00000299192	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:heat3_human(display_long)|uniprotkb:HEATR3(gene name)|psi-mi:HEATR3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_891552.1|ensembl:ENSG00000155393(gene)|ensembl:ENST00000299192(transcript)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR016024(Armadillo-type fold)|mint:Q7Z4Q2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:CjdYLKIHc/A29+XYy4VjNNHJSRU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q01085	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2820828|uniprotkb:A8K3T0|uniprotkb:A8K4L9|ensembl:ENSP00000394902	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tiar_human(display_long)|uniprotkb:TIAL1(gene name)|psi-mi:TIAL1(display_short)|uniprotkb:TIA-1-related protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001029097.1|refseq:NP_003243.1|ensembl:ENSG00000151923(gene)|ensembl:ENST00000436547(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007281"(germ cell development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017145"(stem cell division)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:1903231"(mRNA binding involved in posttranscriptional gene silencing)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034492|interpro:IPR034494|interpro:IPR034496|interpro:IPR035979|mint:Q01085|rcsb pdb:1X4G|rcsb pdb:2CQI|rcsb pdb:2DH7|reactome:R-HSA-6803529|dip:DIP-42425N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:dKWzIWmR/JaCJwsOLUPG2Z1uhH89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9ULX6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-357530|uniprotkb:O94792|uniprotkb:Q96J58|uniprotkb:Q9NRQ0|uniprotkb:Q9UGM0|uniprotkb:B5BU90|uniprotkb:B4DJ74|ensembl:ENSP00000380557	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:akp8l_human(display_long)|uniprotkb:AKAP8L(gene name)|psi-mi:AKAP8L(display_short)|uniprotkb:HRIHFB2018(orf name)|uniprotkb:NAKAP95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)|uniprotkb:Homologous to AKAP95 protein(gene name synonym)|uniprotkb:Helicase A-binding protein 95(gene name synonym)|uniprotkb:NAKAP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001278407.1|refseq:NP_055186.3|dip:DIP-27541N|ensembl:ENSG00000011243(gene)|ensembl:ENST00000397410(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9ULX6	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:SAs8jxuWxLOiWN/TRyjVvr5m/5Y9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P61803	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1052916|uniprotkb:O08552|uniprotkb:O70364|uniprotkb:P46966|uniprotkb:P46968|uniprotkb:Q6FGA3|uniprotkb:Q96GB7|uniprotkb:D3DS25|ensembl:ENSP00000250498	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dad1_human(display_long)|uniprotkb:Defender against cell death 1(gene name synonym)|uniprotkb:DAD1(gene name)|psi-mi:DAD1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001335.1|ensembl:ENSG00000129562(gene)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR003038(Defender against death DAD protein)|mint:P61803|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-446203|reactome:R-HSA-9694548|ensembl:ENST00000250498(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:F7W13/LSSkZUPGLSXoXTfb3i4nY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O60716	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:HgMvbcDKedE291TIvIOqLFT3srw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BTY2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-9050116|uniprotkb:E9PEB6|uniprotkb:Q7Z6V1|uniprotkb:Q7Z6Y2|uniprotkb:Q8NBK4|ensembl:ENSP00000002165	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:fuco2_human(display_long)|uniprotkb:FUCA2(gene name)|psi-mi:FUCA2(display_short)|uniprotkb:Alpha-L-fucoside fucohydrolase 2(gene name synonym)|uniprotkb:PSEC0151(orf name)|uniprotkb:UNQ227/PRO260(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_114409.2|ensembl:ENSG00000001036(gene)|ensembl:ENST00000002165(transcript)|go:"GO:0004560"(alpha-L-fucosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006004"(fucose metabolic process)|go:"GO:0009617"(response to bacterium)|go:"GO:0016139"(glycoside catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR000933("Glycoside hydrolase, family 29 (alpha-L-fucosidase)")|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR016286(Alpha-L-fucosidase)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR018526|interpro:IPR031919|reactome:R-HSA-381426|reactome:R-HSA-6798695|reactome:R-HSA-8957275	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:cBWxxpX9fUF1KQjkaIWoq2n0Vqg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:H7BXI1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11017883|ensembl:ENSP00000275418	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:h7bxi1_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000117868(gene)|ensembl:ENST00000275418(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:eY7GMYJFAFNxAGgMC2JZ0ZRN74M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z4W1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1044712|uniprotkb:Q9BTZ3|uniprotkb:Q9UHY9|ensembl:ENSP00000303356	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dcxr_human(display_long)|uniprotkb:Carbonyl reductase II(gene name synonym)|uniprotkb:Sperm surface protein P34H(gene name synonym)|uniprotkb:Dicarbonyl/L-xylulose reductase(gene name synonym)|uniprotkb:Kidney dicarbonyl reductase(gene name synonym)|uniprotkb:DCXR(gene name)|psi-mi:DCXR(display_short)|uniprotkb:SDR20C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 20C member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001182147.1|refseq:NP_057370.1|ensembl:ENSG00000169738(gene)|ensembl:ENST00000306869(transcript)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005997"(xylulose metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0042732"(D-xylose metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044105"("L-xylulose reductase (NAD+) activity")|go:"GO:0050038"("L-xylulose reductase (NADP+) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|go:"GO:0006006"(glucose metabolic process)|rcsb pdb:1PR9|rcsb pdb:1WNT|rcsb pdb:3D3W|reactome:R-HSA-5661270|reactome:R-HSA-5662853|interpro:IPR036291	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:CaPvjcjdsGXrcl0YtNceGUeTjTk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5T2R2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10762867|uniprotkb:Q53F75|uniprotkb:Q6P473|uniprotkb:Q86WQ8|uniprotkb:Q9Y2W5|ensembl:ENSP00000365388	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dps1_human(display_long)|uniprotkb:All-trans-decaprenyl-diphosphate synthase subunit 1(gene name synonym)|uniprotkb:Decaprenyl pyrophosphate synthase subunit 1(gene name synonym)|uniprotkb:Trans-prenyltransferase 1(gene name synonym)|uniprotkb:PDSS1(gene name)|psi-mi:PDSS1(display_short)|uniprotkb:DPS1(gene name synonym)|uniprotkb:TPRT(gene name synonym)|uniprotkb:Decaprenyl-diphosphate synthase subunit 1(gene name synonym)|uniprotkb:Solanesyl-diphosphate synthase subunit 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001308907.1|refseq:NP_055132.2|ensembl:ENSG00000148459(gene)|ensembl:ENST00000376215(transcript)|go:"GO:0000010"(trans-hexaprenyltranstransferase activity)|go:"GO:0004659"(prenyltransferase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050347"(trans-octaprenyltranstransferase activity)|go:"GO:0097269"(all-trans-decaprenyl-diphosphate synthase activity)|go:"GO:1990234"(transferase complex)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|reactome:R-HSA-2142789	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:n+m/XGsR1P4kNdGpA8ji8CT+5qs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q66K14	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2688824|uniprotkb:O75163|uniprotkb:D3DWQ6|uniprotkb:Q96H49|uniprotkb:Q6MZI2|uniprotkb:Q53EY0|uniprotkb:D3DWQ5|ensembl:ENSP00000349291|ensembl:ENSP00000491373|ensembl:ENSP00000491970	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tbc9b_human(display_long)|uniprotkb:KIAA0676(gene name synonym)|uniprotkb:TBC1D9B(gene name)|psi-mi:TBC1D9B(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055858.2|refseq:NP_942568.2|ensembl:ENSG00000197226(gene)|ensembl:ENSG00000284400(gene)|ensembl:ENST00000356834(transcript)|ensembl:ENST00000639361(transcript)|ensembl:ENST00000639711(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR004182(GRAM)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035969|interpro:IPR036014|interpro:IPR036017|mint:Q66K14	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DdCLCQa69pLYH6eIKdazflUwAKY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P56962	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2797775|uniprotkb:Q4VXC2|ensembl:ENSP00000259400|ensembl:ENSP00000433484|ensembl:ENSP00000435981	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stx17_human(display_long)|uniprotkb:STX17(gene name)|psi-mi:STX17(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011517122.1|refseq:XP_011517123.1|dip:DIP-47297N|refseq:NP_060389.2|ensembl:ENSG00000136874(gene)|ensembl:ENST00000259400(transcript)|ensembl:ENST00000525640(transcript)|ensembl:ENST00000534052(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028676|mint:P56962|rcsb pdb:4WY4|rcsb pdb:7BV4|rcsb pdb:7BV6|reactome:R-HSA-204005	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fakGqDYa9LwX59Q3+PRDIQy/OU49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H300	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943436|uniprotkb:Q96CQ4|uniprotkb:Q9BTJ6|uniprotkb:Q9P1E3|ensembl:ENSP00000325421	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:parl_human(display_long)|uniprotkb:PARL(gene name)|psi-mi:PARL(display_short)|uniprotkb:Mitochondrial intramembrane cleaving protease PARL(gene name synonym)|uniprotkb:PSARL(gene name synonym)|uniprotkb:PRO2207(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001032728.1|refseq:NP_061092.3|ensembl:ENSG00000175193(gene)|ensembl:ENST00000317096(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0006508"(proteolysis)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR022764|interpro:IPR035952|reactome:R-HSA-8949664	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:QQu6yLh8DBzYihAXUoVI4FiLQIw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H019	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2824497|uniprotkb:D3DPJ4|uniprotkb:A6NCB4|uniprotkb:Q63HP1|uniprotkb:B7WNV5|uniprotkb:Q9NUI7|uniprotkb:Q7Z2S7|ensembl:ENSP00000363418|ensembl:ENSP00000363419|ensembl:ENSP00000363421	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mfr1l_human(display_long)|uniprotkb:MTFR1L(gene name)|psi-mi:MTFR1L(display_short)|uniprotkb:FAM54B(gene name synonym)|uniprotkb:HYST1888(orf name)|uniprotkb:MSTP116(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001093095.1|refseq:NP_001093096.1|refseq:NP_001093097.1|refseq:NP_062457.3|interpro:IPR007972(Protein of unknown function DUF729)|ensembl:ENSG00000117640(gene)|ensembl:ENST00000374300(transcript)|ensembl:ENST00000374301(transcript)|ensembl:ENST00000374303(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0009060"(aerobic respiration)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:SVK2WRYbJLfAsZHMblHvoagnYoQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96RG2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1042651|uniprotkb:Q6GSJ5|uniprotkb:Q86XH6|uniprotkb:Q99763|uniprotkb:Q68DY3|uniprotkb:Q9UFR7|uniprotkb:G5E9F1|uniprotkb:Q05BE4|ensembl:ENSP00000234040|ensembl:ENSP00000384016|ensembl:ENSP00000441374	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pask_human(display_long)|uniprotkb:PASK(gene name)|psi-mi:PASK(display_short)|uniprotkb:KIAA0135(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055963.2|refseq:NP_001239048.1|refseq:NP_001239049.1|refseq:NP_001239051.1|refseq:NP_001239053.1|refseq:XP_011509130.1|refseq:XP_011509131.1|refseq:XP_011509132.1|refseq:XP_016859124.1|refseq:XP_016859125.1|ensembl:ENSG00000115687(gene)|ensembl:ENST00000234040(transcript)|ensembl:ENST00000405260(transcript)|ensembl:ENST00000544142(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070092"(regulation of glucagon secretion)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000014(PAS)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035965|rcsb pdb:1LL8|rcsb pdb:3DLS	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:U6MgCPgcbCE9RXKkteT5HZ0aztQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15005	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043352|uniprotkb:Q15507|uniprotkb:Q3KQT0|uniprotkb:Q641R4|uniprotkb:Q6FG65|uniprotkb:Q6IRX0|ensembl:ENSP00000263672|uniprotkb:Q6P1P4|uniprotkb:Q96HU9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:spcs2_human(display_long)|uniprotkb:Microsomal signal peptidase 25 kDa subunit(gene name synonym)|uniprotkb:SPCS2(gene name)|psi-mi:SPCS2(display_short)|uniprotkb:KIAA0102(gene name synonym)|uniprotkb:SPC25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000118363(gene)|ensembl:ENST00000263672(transcript)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)|mint:Q15005|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_055567.2|dip:DIP-47276N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3POhDKvg+aoZiz2XRTC+m77XTAw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q969S3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2687480|ensembl:ENSP00000310042	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:zn622_human(display_long)|uniprotkb:ZPR9(gene name synonym)|uniprotkb:Zinc finger-like protein 9(gene name synonym)|uniprotkb:ZNF622(gene name)|psi-mi:ZNF622(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_219482.1|ensembl:ENSG00000173545(gene)|ensembl:ENST00000308683(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR036236|interpro:IPR040025|interpro:IPR041661|mint:Q969S3|rcsb pdb:6LQM|rcsb pdb:6LSR	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:WUzJA1E/Gz78ud7PgHYxKxUSvU49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6NUM9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11723756|uniprotkb:A6NIK3|uniprotkb:Q53R95|uniprotkb:Q53SA9|uniprotkb:Q6UX05|uniprotkb:Q8N2H5|uniprotkb:Q96FA4|uniprotkb:Q9NXE5|ensembl:ENSP00000295802	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:retst_human(display_long)|uniprotkb:RETSAT(gene name)|psi-mi:RETSAT(display_short)|uniprotkb:PPSIG(gene name synonym)|uniprotkb:UNQ439/PRO872(orf name)|uniprotkb:All-trans-13,14-dihydroretinol saturase(gene name synonym)|uniprotkb:PPAR-alpha-regulated and starvation-induced gene protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060220.3|ensembl:ENSG00000042445(gene)|ensembl:ENST00000295802(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0051786"(all-trans-retinol 13,14-reductase activity)|interpro:IPR036188|reactome:R-HSA-975634	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:LWaHP0k+YymwKjS40faGMX9aNSs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q16513	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9ULD0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3940481|uniprotkb:A8K2G1|uniprotkb:Q9NVA0|uniprotkb:Q8TAN9|uniprotkb:B4DKG2|uniprotkb:B4E193|ensembl:ENSP00000363216	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ogdhl_human(display_long)|uniprotkb:OGDHL(gene name)|psi-mi:OGDHL(display_short)|uniprotkb:KIAA1290(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1-like(gene name synonym)|uniprotkb:Alpha-ketoglutarate dehydrogenase-like(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011538248.1|ensembl:ENSG00000197444(gene)|ensembl:ENST00000374103(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q9ULD0|refseq:NP_001137468.1|refseq:NP_001137469.1|refseq:NP_060715.2|refseq:NP_001334748.1|refseq:NP_001334749.1|refseq:NP_001334751.1|refseq:NP_001334750.1|dip:DIP-61552N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:EDiWt3/TMGuamJ6FgN8l1/whN5g9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q14669	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-308443|uniprotkb:Q15644|ensembl:ENSP00000283943|uniprotkb:D4HL82|uniprotkb:Q14CA3|uniprotkb:Q14CF1|uniprotkb:Q53R87|uniprotkb:Q53TE7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tripc_human(display_long)|uniprotkb:TRIP12(gene name)|psi-mi:TRIP12(display_short)|uniprotkb:Thyroid receptor-interacting protein 12(gene name synonym)|uniprotkb:KIAA0045(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase for Arf(gene name synonym)|uniprotkb:ULF(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase TRIP12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004229.1|refseq:NP_001271143.1|refseq:NP_001271144.1|refseq:NP_001271145.1|ensembl:ENSG00000153827(gene)|ensembl:ENST00000283943(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016607"(nuclear speck)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR035983|interpro:IPR037197|mint:Q14669|reactome:R-HSA-983168|refseq:NP_001335244.1|refseq:NP_001335245.1|ensembl:ENSP00000283943|ensembl:ENST00000389044|ensembl:ENST00000389045|ensembl:ENSP00000373697|ensembl:ENSP00000373696|dip:DIP-58584N	go:"GO:0043229"(intracellular organelle)	-	caution:This sequence has been withdrawn from Uniprot.|crc64:294A7C063A3332DE	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:wzXMKIUEDV4y7YE6PDU+LIPHl7U9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HC98	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-740364|uniprotkb:Q96E83|uniprotkb:Q9ULX2|uniprotkb:B7Z2D9|uniprotkb:Q5TBG3|uniprotkb:Q5TBG9|uniprotkb:Q6FG86|uniprotkb:Q6IAR3|ensembl:ENSP00000319734|ensembl:ENSP00000362705|ensembl:ENSP00000441426|ensembl:ENSP00000442636	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nek6_human(display_long)|uniprotkb:Never in mitosis A-related kinase 6(gene name synonym)|uniprotkb:Protein kinase SID6-1512(gene name synonym)|uniprotkb:NEK6(gene name)|psi-mi:NEK6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001138473.1|refseq:NP_001159639.1|refseq:NP_001159640.1|refseq:NP_001159641.1|refseq:NP_001159642.1|refseq:NP_001159643.1|refseq:NP_055212.2|ensembl:ENSG00000119408(gene)|ensembl:ENST00000320246(transcript)|ensembl:ENST00000373603(transcript)|ensembl:ENST00000545174(transcript)|ensembl:ENST00000546191(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000922"(spindle pole)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-HSA-2980767|reactome:R-HSA-3301854|reactome:R-HSA-9648025|refseq:XP_005251721.1|refseq:XP_006716999.1|refseq:XP_016869706.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:khoXzC0KgPfn38NTbXQEgCldfsc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P55789	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-718281|uniprotkb:Q8TAH6|uniprotkb:Q9H290|uniprotkb:Q9UK40|intact:EBI-6137916|uniprotkb:Q53YM6|ensembl:ENSP00000248114	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:alr_human(display_long)|uniprotkb:Augmenter of liver regeneration(gene name synonym)|uniprotkb:GFER(gene name)|psi-mi:GFER(display_short)|uniprotkb:ALR(gene name synonym)|uniprotkb:HERV1(gene name synonym)|uniprotkb:HPO(gene name synonym)|uniprotkb:Hepatopoietin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005253.3|ensembl:ENSG00000127554(gene)|ensembl:ENST00000248114(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0008083"(growth factor activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR017905|interpro:IPR036774|interpro:IPR039799|rcsb pdb:3MBG|rcsb pdb:3O55|rcsb pdb:3TK0|rcsb pdb:3U2L|rcsb pdb:3U2M|rcsb pdb:3U5S|rcsb pdb:4LDK|reactome:R-HSA-1268020	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ttWSaYxpd3WUg61NQC7eiybRFUg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N6L1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1053775|uniprotkb:Q86XW2|uniprotkb:Q8IWS4|uniprotkb:Q6PG45|uniprotkb:B2R4Q1|ensembl:ENSP00000295682	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ktap2_human(display_long)|uniprotkb:KRTCAP2(gene name)|psi-mi:KRTCAP2(display_short)|uniprotkb:KCP2(gene name synonym)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_776251.1|ensembl:ENSG00000163463(gene)|ensembl:ENST00000295682(transcript)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042543"(protein N-linked glycosylation via arginine)|interpro:IPR018614	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:UV1w5dUgiiefNipBAMcEKj/WMIY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43819	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-357012|uniprotkb:Q3T1B5|uniprotkb:Q9UK87|ensembl:ENSP00000252785|ensembl:ENSP00000379046|ensembl:ENSP00000444242|ensembl:ENSP00000444433	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sco2_human(display_long)|uniprotkb:SCO2(gene name)|psi-mi:SCO2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001162580.1|refseq:NP_001162581.1|refseq:NP_001162582.1|refseq:NP_005129.2|dip:DIP-46088N|go:"GO:0003012"(muscle system process)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0014823"(response to activity)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016531"(copper chaperone activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR003782(Copper chaperone SCO1/SenC)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017276(Synthesis of cytochrome c oxidase, Sco1/Sco2)|interpro:IPR036249|mint:O43819|rcsb pdb:2RLI|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|ensembl:ENSG00000284194(gene)|ensembl:ENST00000252785(transcript)|ensembl:ENST00000395693(transcript)|ensembl:ENST00000535425(transcript)|ensembl:ENST00000543927(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001701"(in utero embryonic development)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RaD9DPaOnFKJvwNRUK9KQdptmqc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NHP8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10968883|ensembl:ENSP00000280800|uniprotkb:F5H5E2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:plbl2_human(display_long)|uniprotkb:PLBD2(gene name)|psi-mi:PLBD2(display_short)|uniprotkb:76 kDa protein(gene name synonym)|uniprotkb:LAMA-like protein 2(gene name synonym)|uniprotkb:Lamina ancestor homolog 2(gene name synonym)|uniprotkb:Phospholipase B domain-containing protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001153199.1|refseq:NP_775813.2|ensembl:ENSG00000151176(gene)|ensembl:ENST00000280800(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007000(Laminin A)|interpro:IPR043040|interpro:IPR043041|interpro:IPR043042	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Ae7gQMoB6XQQxqLlG46cG3ijM089606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P42695	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-722805|uniprotkb:A6NFS2|uniprotkb:Q4KMQ9|ensembl:ENSP00000433681	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cndd3_human(display_long)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)|uniprotkb:NCAPD3(gene name)|psi-mi:NCAPD3(display_short)|uniprotkb:CAPD3(gene name synonym)|uniprotkb:KIAA0056(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056076.1|dip:DIP-43903N|ensembl:ENSG00000151503(gene)|ensembl:ENST00000534548(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026971|interpro:IPR032682|mint:P42695|reactome:R-HSA-2299718	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:z5WYLlrGt33uAM9NRN9SQeHFDaA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6NTF9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6268599|uniprotkb:Q7L534|uniprotkb:Q9H5W6|uniprotkb:Q9UDT2|uniprotkb:Q9HBK7|ensembl:ENSP00000006777	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rhbd2_human(display_long)|uniprotkb:RHBDD2(gene name)|psi-mi:RHBDD2(display_short)|uniprotkb:RHBDL7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000006777|ensembl:ENST00000318622|ensembl:ENSP00000314144|ensembl:ENST00000428119|ensembl:ENSP00000391232|refseq:XP_005250568.1|refseq:NP_001035546.1|refseq:NP_001035547.1|refseq:NP_001333115.1|refseq:NP_001333116.1|refseq:NP_001333117.1|ensembl:ENSG00000005486(gene)|ensembl:ENST00000006777(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR022764|interpro:IPR035952|mint:Q6NTF9	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:j9yYUE7lTSD2kC5GmqiHbjQcVQM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96H55	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10983249|uniprotkb:Q59GS4|uniprotkb:Q9H5X2|ensembl:ENSP00000479518|ensembl:ENSP00000480242	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:myo19_human(display_long)|uniprotkb:MYO19(gene name)|psi-mi:MYO19(display_short)|uniprotkb:MYOHD1(gene name synonym)|uniprotkb:Myosin head domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001028752.1|refseq:NP_001157207.1|refseq:NP_079385.2|ensembl:ENSG00000278259(gene)|ensembl:ENSG00000278372(gene)|ensembl:ENST00000614623(transcript)|ensembl:ENST00000618519(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034642"(mitochondrion migration along actin filament)|go:"GO:0051015"(actin filament binding)|go:"GO:0060002"(plus-end directed microfilament motor activity)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR027417|interpro:IPR036035|interpro:IPR036961|mint:Q96H55|reactome:R-HSA-9013419|reactome:R-HSA-9013425	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:coJYx89cip3wKcsCF65cbMPBt7Y9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15120	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1383915|uniprotkb:B4DXG6|ensembl:ENSP00000368460|ensembl:ENSP00000497727	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pdk3_human(display_long)|uniprotkb:Pyruvate dehydrogenase kinase isoform 3(gene name synonym)|uniprotkb:PDK3(gene name)|psi-mi:PDK3(display_short)|uniprotkb:PDHK3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005382.1|refseq:NP_001135858.1|dip:DIP-29498N|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:Q15120|rcsb pdb:1Y8N|rcsb pdb:1Y8O|rcsb pdb:1Y8P|rcsb pdb:2PNR|rcsb pdb:2Q8I|reactome:R-HSA-204174|reactome:R-HSA-5362517|ensembl:ENSG00000067992(gene)|ensembl:ENST00000379162(transcript)|ensembl:ENST00000648777(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010510"(regulation of acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0071333"(cellular response to glucose stimulus)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Q+/L48rFsQ7HDy8zDZWSfHzVghU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UHR6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2557592|uniprotkb:Q8IUV0|uniprotkb:Q3SY14|ensembl:ENSP00000308548	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:znhi2_human(display_long)|uniprotkb:ZNHIT2(gene name)|psi-mi:ZNHIT2(display_short)|uniprotkb:Protein FON(gene name synonym)|uniprotkb:C11orf5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055020.1|ensembl:ENSG00000174276(gene)|ensembl:ENST00000310597(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR039646|rcsb pdb:1X4S	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:kzpAH9lDvvANjOhTrTcuUtQwkEU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BTT6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-713489|uniprotkb:Q9HAC0|uniprotkb:Q9NVF1|ensembl:ENSP00000359925|uniprotkb:Q5TGN3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lrrc1_human(display_long)|uniprotkb:LAP and no PDZ protein(gene name synonym)|uniprotkb:LANO adapter protein(gene name synonym)|uniprotkb:LRRC1(gene name)|psi-mi:LRRC1(display_short)|uniprotkb:LANO(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000137269(gene)|ensembl:ENST00000370888(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|reactome:R-HSA-9696270|refseq:NP_060684.4|refseq:XP_011513028.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FJ/8+gehIT2j2bJ8gYpkDht+//I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H3N1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1051115|uniprotkb:Q8N487|uniprotkb:Q8NBN5|uniprotkb:Q9Y4T6|uniprotkb:B2R7A4|ensembl:ENSP00000393316	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tmx1_human(display_long)|uniprotkb:Transmembrane Trx-related protein(gene name synonym)|uniprotkb:TMX1(gene name)|psi-mi:TMX1(display_short)|uniprotkb:TXNDC1(gene name synonym)|uniprotkb:TMX(gene name synonym)|uniprotkb:TXNDC(gene name synonym)|uniprotkb:PSEC0085(orf name)|uniprotkb:UNQ235/PRO268(orf name)|uniprotkb:Thioredoxin domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_110382.3|ensembl:ENSG00000139921(gene)|ensembl:ENST00000457354(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:Q9H3N1|rcsb pdb:1X5E	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ZJH5N22Dnrk+SXa3Ysqqfu1md/I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9P2W9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-725334|uniprotkb:Q596L3|uniprotkb:Q5TZP5|ensembl:ENSP00000305810	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stx18_human(display_long)|uniprotkb:Cell growth-inhibiting gene 9 protein(gene name synonym)|uniprotkb:STX18(gene name)|psi-mi:STX18(display_short)|uniprotkb:GIG9(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_058626.1|refseq:NP_001333211.1|refseq:NP_001333210.1|refseq:NP_001333229.1|ensembl:ENSG00000168818(gene)|ensembl:ENST00000306200(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1902117"(positive regulation of organelle assembly)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR019529|mint:Q9P2W9|reactome:R-HSA-6811434|dip:DIP-37617N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:QpvkckDM1D5Jaty6AmK3vEwRZts9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HD45	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2814047|uniprotkb:Q9NWL8|uniprotkb:Q5TB57|uniprotkb:Q9UHW8|uniprotkb:Q6UWE7|uniprotkb:Q9P0G9|ensembl:ENSP00000360184	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tm9s3_human(display_long)|uniprotkb:TM9SF3(gene name)|psi-mi:TM9SF3(display_short)|uniprotkb:SMBP(gene name synonym)|uniprotkb:EP70-P-iso(gene name synonym)|uniprotkb:SM-11044-binding protein(gene name synonym)|uniprotkb:UNQ245/PRO282(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_064508.3|ensembl:ENSG00000077147(gene)|ensembl:ENST00000371142(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|mint:Q9HD45	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/9Z/a+36wE2FTbIyQ/zWPPGo9Rs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96EK5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-744150|uniprotkb:A8K5M8|uniprotkb:Q9BR89|uniprotkb:Q9ULE1|uniprotkb:Q9Y428|ensembl:ENSP00000354848	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kbp_human(display_long)|uniprotkb:KIF1-binding protein(gene name synonym)|uniprotkb:Kinesin family binding protein(gene name synonym)|uniprotkb:KBP(gene name synonym)|uniprotkb:KIAA1279(gene name synonym)|uniprotkb:KIFBP(gene name)|psi-mi:KIFBP(display_short)|uniprotkb:KIF1BP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056449.1|ensembl:ENSG00000198954(gene)|ensembl:ENST00000361983(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007399"(nervous system development)|go:"GO:0019894"(kinesin binding)|go:"GO:0030154"(cell differentiation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR022083|mint:Q96EK5|rcsb pdb:6ZPG|rcsb pdb:6ZPH	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:wiRR4tDx91/cAUb2ANX42T+vhyI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BTT0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2685059|uniprotkb:Q5TB18|uniprotkb:Q8N1S4|uniprotkb:Q8WWW9|uniprotkb:B4E0I6|uniprotkb:E9PEA6|uniprotkb:Q5TB20|ensembl:ENSP00000463154	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:an32e_human(display_long)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:ANP32E(gene name)|psi-mi:ANP32E(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001129950.1|refseq:NP_001129951.1|refseq:NP_112182.1|refseq:NP_001267488.1|refseq:NP_001267489.1|ensembl:ENSG00000143401(gene)|ensembl:ENST00000583931(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043486"(histone exchange)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q9BTT0|rcsb pdb:4CAY|rcsb pdb:4NFT	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:byeFwwxqINXwewx0Gx/QXSyes8g9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HBM0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11337963|uniprotkb:Q9NVW0|uniprotkb:Q9UF91|uniprotkb:Q9H2F4|uniprotkb:Q9NT70|uniprotkb:Q9H2U5|uniprotkb:Q6P1Q3|ensembl:ENSP00000410083	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:veza_human(display_long)|uniprotkb:VEZT(gene name)|psi-mi:VEZT(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060069.3|refseq:XP_006719553.1|refseq:XP_016875091.1|ensembl:ENSG00000028203(gene)|ensembl:ENST00000436874(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR026858|interpro:IPR026859	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RYaab97a5nn3YOaR7O7/rb9AjXk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96GC9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2800296|uniprotkb:B4DVV9|uniprotkb:Q9H0P4|uniprotkb:Q9P089|ensembl:ENSP00000262291	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:vmp1_human(display_long)|uniprotkb:TDC1(gene name synonym)|uniprotkb:VMP1(gene name)|psi-mi:VMP1(display_short)|uniprotkb:TMEM49(gene name synonym)|uniprotkb:HSPC292(orf name)|uniprotkb:Transmembrane protein 49(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_112200.2|refseq:NP_001316323.1|refseq:NP_001316326.1|refseq:NP_001316331.1|ensembl:ENSG00000062716(gene)|ensembl:ENST00000262291(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007566"(embryo implantation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034329"(cell junction assembly)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR032816|go:"GO:0007030"(Golgi organization)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:jp+0BTpb7FA21nyt6TN4DglKakQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q68EM7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1642807|uniprotkb:A8K6M6|uniprotkb:Q6ZUS4|uniprotkb:Q7Z2F2|uniprotkb:Q8NDG2|uniprotkb:Q96KS2|uniprotkb:Q96KS3|uniprotkb:Q96SS8|uniprotkb:Q9BVF6|uniprotkb:Q9H8U5|uniprotkb:Q9NW54|intact:EBI-2398436|ensembl:ENSP00000289968|ensembl:ENSP00000500372	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rhg17_human(display_long)|uniprotkb:ARHGAP17(gene name)|psi-mi:ARHGAP17(display_short)|uniprotkb:Rho-type GTPase-activating protein 17(gene name synonym)|uniprotkb:RhoGAP interacting with CIP4 homologs protein 1(gene name synonym)|uniprotkb:MSTP066(orf name)|uniprotkb:MSTP110(orf name)|uniprotkb:RICH1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001006635.1|refseq:NP_060524.4|ensembl:ENSG00000140750(gene)|ensembl:ENSG00000288353(gene)|ensembl:ENST00000289968(transcript)|ensembl:ENST00000673560(transcript)|go:"GO:0005096"(GTPase activator activity)|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013423|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035020"(regulation of Rac protein signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR004148(BAR)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|go:"GO:0005654"(nucleoplasm)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ShqZATP0+ROgRhy0Afi5gqZ1JVY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6P6C2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5280436|uniprotkb:D3DXC6|uniprotkb:Q9NXD6|uniprotkb:B4DVJ4|ensembl:ENSP00000382091	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:alkb5_human(display_long)|uniprotkb:ALKBH5(gene name)|psi-mi:ALKBH5(display_short)|uniprotkb:ABH5(gene name synonym)|uniprotkb:OFOXD1(gene name synonym)|uniprotkb:Alkylated DNA repair protein alkB homolog 5(gene name synonym)|uniprotkb:Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060228.3|ensembl:ENSP00000382091|ensembl:ENSG00000091542(gene)|ensembl:ENST00000399138(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0035553"(oxidative single-stranded RNA demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:1990931"(mRNA N6-methyladenosine dioxygenase activity)|interpro:IPR027450|interpro:IPR032860|interpro:IPR037151|rcsb pdb:4NJ4|rcsb pdb:4NRM|rcsb pdb:4NRO|rcsb pdb:4NRP|rcsb pdb:4NRQ|rcsb pdb:4O61|rcsb pdb:4O7X|rcsb pdb:4OCT|reactome:R-HSA-73943|go:"GO:0043488"(regulation of mRNA stability)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:PD25zPFQPS2gC0z7A8wrWMON3Bk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q99538	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2511794|ensembl:ENSP00000334052|ensembl:ENSP00000376911|uniprotkb:Q86TV2|uniprotkb:Q86TV3|uniprotkb:Q9BTY1|uniprotkb:O00123|intact:EBI-10963477	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lgmn_human(display_long)|uniprotkb:LGMN(gene name)|psi-mi:LGMN(display_short)|uniprotkb:PRSC1(gene name synonym)|uniprotkb:Asparaginyl endopeptidase(gene name synonym)|uniprotkb:Protease, cysteine 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000100600(gene)|ensembl:ENST00000334869(transcript)|ensembl:ENST00000393218(transcript)|go:"GO:0003014"(renal system process)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006624"(vacuolar protein processing)|go:"GO:0007613"(memory)|go:"GO:0008233"(peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097264"(self proteolysis)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901185"(negative regulation of ERBB signaling pathway)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001096(Peptidase C13, legumain)|interpro:IPR043577|mint:Q99538|rcsb pdb:4AW9|rcsb pdb:4AWA|rcsb pdb:4AWB|rcsb pdb:4FGU|rcsb pdb:4N6N|rcsb pdb:4N6O|rcsb pdb:5LU8|rcsb pdb:5LU9|rcsb pdb:5LUA|rcsb pdb:5LUB|reactome:R-HSA-1679131|go:"GO:0040015"(negative regulation of multicellular organism growth)|reactome:R-HSA-196791|reactome:R-HSA-2132295|refseq:XP_005267919.1|refseq:XP_005267920.1|refseq:NP_001008530.1|refseq:NP_005597.3|refseq:XP_016876952.1|refseq:XP_016876953.1|refseq:XP_016876954.1|refseq:XP_016876955.1|refseq:XP_016876956.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:W2jPq8/peH5iXt1wmbm8lFnkJwM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7LGA3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5461291|ensembl:ENSP00000359581|uniprotkb:D3DT22|uniprotkb:O75036|uniprotkb:Q32NB5|uniprotkb:Q8TAC5|uniprotkb:Q9H441|uniprotkb:Q9NUJ9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hs2st_human(display_long)|uniprotkb:HS2ST1(gene name)|psi-mi:HS2ST1(display_short)|uniprotkb:HS2ST(gene name synonym)|uniprotkb:KIAA0448(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000153936(gene)|ensembl:ENST00000370550(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004394"(heparan sulfate 2-O-sulfotransferase activity)|go:"GO:0006024"(glycosaminoglycan biosynthetic process)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0015014"(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)|go:"GO:0015015"(heparan sulfate proteoglycan biosynthetic process, enzymatic modification)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR007734(Heparan sulphate 2-O-sulphotransferase)|interpro:IPR027417|mint:Q7LGA3|reactome:R-HSA-2022928|interpro:IPR005331(Carbohydrate sulphotransferase, 8-13)|refseq:NP_001127964.1|refseq:NP_036394.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:96+iUitOmSLSpaEzhZu+9fZXLEQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P36507	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1056930|ensembl:ENSP00000262948|intact:EBI-15586042	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mp2k2_human(display_long)|uniprotkb:MAP2K2(gene name)|psi-mi:MAP2K2(display_short)|uniprotkb:MEK2(gene name synonym)|uniprotkb:MKK2(gene name synonym)|uniprotkb:PRKMK2(gene name synonym)|uniprotkb:ERK activator kinase 2(gene name synonym)|uniprotkb:MAPK/ERK kinase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_109587.1|ensembl:ENSG00000126934(gene)|ensembl:ENST00000262948(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P36507|rcsb pdb:1S9I|rcsb pdb:4H3Q|reactome:R-HSA-112411|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|go:"GO:0005634"(nucleus)|dip:DIP-29119N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:JnGMm7dA0eZgBV4A/n+ZjE8ATq49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N442	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5460727|uniprotkb:Q5XKM8|uniprotkb:Q9H710|uniprotkb:Q9H8U4|ensembl:ENSP00000281543	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:guf1_human(display_long)|uniprotkb:GUF1(gene name)|psi-mi:GUF1(display_short)|uniprotkb:Elongation factor 4 homolog(gene name synonym)|uniprotkb:GTPase GUF1(gene name synonym)|uniprotkb:Ribosomal back-translocase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_068746.2|interpro:IPR031157|interpro:IPR035647|interpro:IPR035654|interpro:IPR038363|ensembl:ENSG00000151806(gene)|ensembl:ENST00000281543(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006297(GTP-binding protein LepA)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR013842(GTP-binding protein LepA, C-terminal)|interpro:IPR027417	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8qGEN4UaBdf2SZbCrIzSU2qDugo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P20290	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1054687|uniprotkb:Q13893|uniprotkb:Q76M56|uniprotkb:A8K510|ensembl:ENSP00000369965	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:btf3_human(display_long)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001032726.1|refseq:NP_001198.2|ensembl:ENSG00000145741(gene)|ensembl:ENST00000380591(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|mint:P20290|rcsb pdb:3LKX|rcsb pdb:3MCB	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TU7PtK2KVrzmdfaTdWcHloiRZYg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15269	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-722224|uniprotkb:Q96A77|uniprotkb:B2RAG8|ensembl:ENSP00000291576	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pwp2_human(display_long)|uniprotkb:PWP2(gene name)|psi-mi:PWP2(display_short)|uniprotkb:PWP2H(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005040.2|refseq:XP_006723973.1|refseq:XP_011507205.1|ensembl:ENSG00000241945(gene)|ensembl:ENST00000291576(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR027145|reactome:R-HSA-6790901|reactome:R-HSA-6791226	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:PYs2LKd3EMjAnp0engZvZn0CeBo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15800	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-949102|ensembl:ENSP00000261507|uniprotkb:Q32Q24|uniprotkb:A8K8Q3|uniprotkb:D3DP32|uniprotkb:A8MYF6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:msmo1_human(display_long)|uniprotkb:MSMO1(gene name)|psi-mi:MSMO1(display_short)|uniprotkb:SC4MOL(gene name synonym)|uniprotkb:DESP4(gene name synonym)|uniprotkb:ERG25(gene name synonym)|uniprotkb:Sterol-C4-methyl oxidase(gene name synonym)|uniprotkb:C-4 methylsterol oxidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR006694(Fatty acid hydroxylase)|reactome:R-HSA-191273|ensembl:ENSG00000052802(gene)|ensembl:ENST00000261507(transcript)|go:"GO:0000254"(C-4 methylsterol oxidase activity)|go:"GO:0005506"(iron ion binding)|refseq:NP_001017369.1|refseq:NP_006736.1|refseq:XP_005263233.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:w15LOzo1xKRa05LTpCJO5IU9RXw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y6E0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q00535	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1041567|uniprotkb:A1XKG3|ensembl:ENSP00000419782	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cdk5_human(display_long)|uniprotkb:CDK5(gene name)|psi-mi:CDK5(display_short)|uniprotkb:Cell division protein kinase 5(gene name synonym)|uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)|uniprotkb:CDKN5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001157882.1|refseq:NP_004926.1|ensembl:ENSG00000164885(gene)|ensembl:ENST00000485972(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048156"(tau protein binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048511"(rhythmic process)|go:"GO:0048675"(axon extension)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070509"(calcium ion import)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q00535|rcsb pdb:1H4L|rcsb pdb:1LFR|rcsb pdb:1UNG|rcsb pdb:1UNH|rcsb pdb:1UNL|rcsb pdb:3O0G|rcsb pdb:4AU8|reactome:R-HSA-180024|reactome:R-HSA-399956|reactome:R-HSA-6804756|reactome:R-HSA-8862803|reactome:R-HSA-9031628|reactome:R-HSA-9032845|reactome:R-HSA-983231|dip:DIP-24221N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:NddS77Gpf0Gt5O3MPylAUfJ7QOE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14929	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95140	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3324756|uniprotkb:A8K1B3|uniprotkb:O95572|uniprotkb:Q5JXC3|uniprotkb:Q5JXC4|uniprotkb:Q9H131|uniprotkb:Q9NSX8|ensembl:ENSP00000235329|ensembl:ENSP00000416338|ensembl:ENSP00000502151|ensembl:ENSP00000502185|ensembl:ENSP00000502362|ensembl:ENSP00000502404|ensembl:ENSP00000502623|ensembl:ENSP00000501646|ensembl:ENSP00000501716|ensembl:ENSP00000501776	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mfn2_human(display_long)|uniprotkb:MFN2(gene name)|psi-mi:MFN2(display_short)|uniprotkb:CPRP1(gene name synonym)|uniprotkb:KIAA0214(gene name synonym)|uniprotkb:Transmembrane GTPase MFN2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001121132.1|refseq:NP_055689.1|refseq:XP_005263600.1|refseq:XP_005263602.1|refseq:XP_005263604.1|refseq:XP_005263605.1|ensembl:ENSG00000116688(gene)|ensembl:ENST00000235329(transcript)|ensembl:ENST00000444836(transcript)|ensembl:ENST00000674548(transcript)|ensembl:ENST00000674817(transcript)|ensembl:ENST00000674910(transcript)|ensembl:ENST00000675053(transcript)|ensembl:ENST00000675113(transcript)|ensembl:ENST00000675231(transcript)|ensembl:ENST00000675919(transcript)|ensembl:ENST00000676293(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031306"(intrinsic component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR006884(Fzo-like conserved region)|interpro:IPR022812|interpro:IPR027089|interpro:IPR027094|interpro:IPR027417|interpro:IPR030381|mint:O95140|rcsb pdb:6JFK|rcsb pdb:6JFL|rcsb pdb:6JFM|reactome:R-HSA-5205685|reactome:R-HSA-9013419|reactome:R-HSA-983231|dip:DIP-42832N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:E54l4ZR9fs6qvZJczOOibxVlJx49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P01892	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2839473|uniprotkb:Q9TPY0|uniprotkb:Q29680|uniprotkb:Q29899|uniprotkb:P06338|uniprotkb:P30445|uniprotkb:Q95352|uniprotkb:Q9TQI3|uniprotkb:Q95380|uniprotkb:P30444|uniprotkb:Q9TPX8|uniprotkb:O19619|uniprotkb:P30446|uniprotkb:Q9TQH5|uniprotkb:P10313|uniprotkb:Q9TPX9|uniprotkb:P30514|uniprotkb:Q29837	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:1a02_human(display_long)|uniprotkb:HLA-A(gene name)|psi-mi:HLA-A(display_short)|uniprotkb:HLAA(gene name synonym)|uniprotkb:Human leukocyte antigen A*02(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	rcsb pdb:4MNQ|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5C0D|rcsb pdb:5C0E|rcsb pdb:5C0F|rcsb pdb:5C0G|rcsb pdb:5C0I|rcsb pdb:5C0J|rcsb pdb:5HYJ|rcsb pdb:4NNX|rcsb pdb:4NNY|rcsb pdb:4NO0|rcsb pdb:4NO2|rcsb pdb:4OV5|rcsb pdb:4UQ3|ensembl:ENSG00000227715|ensembl:ENSP00000448077|ensembl:ENST00000547522|rcsb pdb:5SWQ|rcsb pdb:5HHN|rcsb pdb:5HHO|rcsb pdb:5HHP|rcsb pdb:5HHQ|rcsb pdb:4L29|rcsb pdb:4L3C|rcsb pdb:5NME|rcsb pdb:5NMF|rcsb pdb:5HHM|rcsb pdb:5D9S|rcsb pdb:5DDH|rcsb pdb:5E6I|rcsb pdb:5IRO|rcsb pdb:6D7G|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016567"(protein ubiquitination)|rcsb pdb:5D2L|rcsb pdb:5D2N|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0030881"(beta-2-microglobulin binding)|go:"GO:0070971"(endoplasmic reticulum exit site)|rcsb pdb:4WJ5|go:"GO:0003723"(RNA binding)|go:"GO:0055038"(recycling endosome membrane)|rcsb pdb:5E00|rcsb pdb:5NMH|rcsb pdb:5NMK|rcsb pdb:6EQA|rcsb pdb:6EQB|rcsb pdb:6EWA|rcsb pdb:6EWC|rcsb pdb:6EWO|rcsb pdb:4EMZ|rcsb pdb:4EN2|rcsb pdb:5EU3|rcsb pdb:5EU4|rcsb pdb:5EU5|rcsb pdb:5EU6|rcsb pdb:4NO3|rcsb pdb:4NO5|rcsb pdb:4QOK|rcsb pdb:4U6X|rcsb pdb:4U6Y|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR010579(MHC class I, alpha chain, C-terminal)|go:"GO:0031901"(early endosome membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0000139"(Golgi membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0042612"(MHC class I protein complex)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0050690"(regulation of defense response to virus by virus)|go:"GO:0060337"(type I interferon signaling pathway)|rcsb pdb:1AKJ|rcsb pdb:1AO7|rcsb pdb:1AQD|rcsb pdb:1B0G|rcsb pdb:1B0R|rcsb pdb:1BD2|rcsb pdb:1DUY|rcsb pdb:1DUZ|rcsb pdb:1EEY|rcsb pdb:1EEZ|rcsb pdb:1HHG|rcsb pdb:1HHH|rcsb pdb:1HHI|rcsb pdb:1HHJ|rcsb pdb:1HHK|rcsb pdb:1HLA|rcsb pdb:1I1F|rcsb pdb:1I1Y|rcsb pdb:1I4F|rcsb pdb:1I7R|rcsb pdb:1I7T|rcsb pdb:1I7U|rcsb pdb:1IM3|rcsb pdb:1JF1|rcsb pdb:1JHT|rcsb pdb:1LP9|rcsb pdb:1OGA|rcsb pdb:1P7Q|rcsb pdb:1QEW|rcsb pdb:1QR1|rcsb pdb:1QRN|rcsb pdb:1QSE|rcsb pdb:1QSF|rcsb pdb:1S8D|rcsb pdb:1S9W|rcsb pdb:1S9X|rcsb pdb:1S9Y|rcsb pdb:1T1W|rcsb pdb:1T1X|rcsb pdb:1T1Y|rcsb pdb:1T1Z|rcsb pdb:1T20|rcsb pdb:1T21|rcsb pdb:1T22|rcsb pdb:1TVB|rcsb pdb:1TVH|rcsb pdb:1UR7|rcsb pdb:2AV1|rcsb pdb:2AV7|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2C7U|rcsb pdb:2CLR|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GIT|rcsb pdb:2GJ6|rcsb pdb:2GT9|rcsb pdb:2GTW|rcsb pdb:2GTZ|rcsb pdb:2GUO|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PYE|rcsb pdb:2UWE|rcsb pdb:2V2W|rcsb pdb:2V2X|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLL|rcsb pdb:2VLR|rcsb pdb:2X4N|rcsb pdb:2X4O|rcsb pdb:2X4P|rcsb pdb:2X4Q|rcsb pdb:2X4R|rcsb pdb:2X4S|rcsb pdb:2X4T|rcsb pdb:2X4U|rcsb pdb:2X70|rcsb pdb:3BGM|rcsb pdb:3BH8|rcsb pdb:3BH9|rcsb pdb:3BHB|rcsb pdb:3D25|rcsb pdb:3D39|rcsb pdb:3D3V|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3FQT|rcsb pdb:3FQU|rcsb pdb:3FQW|rcsb pdb:3FQX|rcsb pdb:3FT2|rcsb pdb:3FT3|rcsb pdb:3FT4|rcsb pdb:3GIV|rcsb pdb:3GJF|rcsb pdb:3GSN|rcsb pdb:3GSO|rcsb pdb:3GSQ|rcsb pdb:3GSR|rcsb pdb:3GSU|rcsb pdb:3GSV|rcsb pdb:3GSW|rcsb pdb:3GSX|rcsb pdb:3H7B|rcsb pdb:3H9H|rcsb pdb:3H9S|rcsb pdb:3HAE|rcsb pdb:3HLA|rcsb pdb:3HPJ|rcsb pdb:3I6G|rcsb pdb:3I6K|rcsb pdb:3IXA|rcsb pdb:3KLA|rcsb pdb:3MGO|rcsb pdb:3MGT|rcsb pdb:3MR9|rcsb pdb:3MRB|rcsb pdb:3MRC|rcsb pdb:3MRD|rcsb pdb:3MRE|rcsb pdb:3MRF|rcsb pdb:3MRG|rcsb pdb:3MRH|rcsb pdb:3MRI|rcsb pdb:3MRJ|rcsb pdb:3MRK|rcsb pdb:3MRL|rcsb pdb:3MRM|rcsb pdb:3MRN|rcsb pdb:3MRO|rcsb pdb:3MRP|rcsb pdb:3MRQ|rcsb pdb:3MRR|rcsb pdb:3MYJ|rcsb pdb:3O3A|rcsb pdb:3O3B|rcsb pdb:3O3D|rcsb pdb:3O3E|rcsb pdb:3O4L|rcsb pdb:3PWJ|rcsb pdb:3PWL|rcsb pdb:3PWN|rcsb pdb:3PWP|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFO|rcsb pdb:4JFP|rcsb pdb:4JFQ|go:"GO:0002486"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent)|go:"GO:0009986"(cell surface)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0046977"(TAP binding)|go:"GO:2000568"(positive regulation of memory T cell activation)|rcsb pdb:3QFD|rcsb pdb:4K7F|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0002480"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent)|go:"GO:0030670"(phagocytic vesicle membrane)|rcsb pdb:3QFJ|rcsb pdb:3REW|rcsb pdb:3UTQ|rcsb pdb:3UTS|rcsb pdb:3UTT|rcsb pdb:5NMG|rcsb pdb:5NHT|rcsb pdb:5NQK|rcsb pdb:4WUU|rcsb pdb:4E5X|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:2000566"(positive regulation of CD8-positive, alpha-beta T cell proliferation)|rcsb pdb:3V5D|rcsb pdb:3V5H|rcsb pdb:3V5K|rcsb pdb:4I4W|rcsb pdb:5EOT|rcsb pdb:5EUO|rcsb pdb:5F7D|rcsb pdb:5F9J|rcsb pdb:5FA3|rcsb pdb:5FA4|rcsb pdb:5FDW|rcsb pdb:5MEN|rcsb pdb:5MEO|rcsb pdb:5MEP|rcsb pdb:5MEQ|rcsb pdb:5MER|rcsb pdb:3TO2|rcsb pdb:4GKN|rcsb pdb:4GKS|rcsb pdb:4EUP|reactome:R-HSA-198933|reactome:R-HSA-877300|reactome:R-HSA-909733|reactome:R-HSA-983170|go:"GO:0042608"(T cell receptor binding)|rcsb pdb:4L3E|ensembl:ENSG00000235657|ensembl:ENSP00000403575|ensembl:ENSP00000447962|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0019885"(antigen processing and presentation of endogenous peptide antigen via MHC class I)|go:"GO:2001187"(positive regulation of CD8-positive, alpha-beta T cell activation)|reactome:R-HSA-1236974|reactome:R-HSA-1236977|reactome:R-HSA-164940|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0042605"(peptide antigen binding)|rcsb pdb:4FTV|rcsb pdb:5E9D|rcsb pdb:5C07|rcsb pdb:5C08|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0050776"(regulation of immune response)|ensembl:ENST00000457879|ensembl:ENST00000547271|go:"GO:0051290"(protein heterotetramerization)|rcsb pdb:5ISZ|rcsb pdb:5JHD|rcsb pdb:5N1Y|go:"GO:0002250"(adaptive immune response)|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:6D78|rcsb pdb:6DKP|rcsb pdb:5ENW|reactome:R-HSA-8866654|rcsb pdb:5JZI|interpro:IPR036179|interpro:IPR037055|rcsb pdb:5TEZ|rcsb pdb:5WSH|mint:P01892|rcsb pdb:5N6B|rcsb pdb:5W1W|rcsb pdb:6AM5|rcsb pdb:6AMT|rcsb pdb:6AMU|rcsb pdb:6APN|go:"GO:0002485"(antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent)|go:"GO:0036037"(CD8-positive, alpha-beta T cell activation)|go:"GO:0042590"(antigen processing and presentation of exogenous peptide antigen via MHC class I)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0062061"(TAP complex binding)|rcsb pdb:6G3J	go:"GO:0043229"(intracellular organelle)	-	no-uniprot-update:Deprecated HLA-A AC, merged into a different UniProt canonical but we have mutation features in variable positions.|comment:"Allele =A*02:01:01:01"|comment:"Allele =A*02:01:01:01 according to IPD-IMGT/HLA database"	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:oTL0BWZeACoxMc++WgT0XDz+sNg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NRN7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-740884|ensembl:ENSP00000278618|uniprotkb:Q9C068|uniprotkb:Q9P0Q3|uniprotkb:Q9UG80|uniprotkb:Q9Y389|uniprotkb:B2R6D1|uniprotkb:B4DDW7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:adppt_human(display_long)|uniprotkb:4'-phosphopantetheinyl transferase(gene name synonym)|uniprotkb:Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase(gene name synonym)|uniprotkb:LYS5 ortholog(gene name synonym)|uniprotkb:AASDHPPT(gene name)|psi-mi:AASDHPPT(display_short)|uniprotkb:CGI-80(orf name)|uniprotkb:HAH-P(orf name)|uniprotkb:HSPC223(orf name)|uniprotkb:x0005(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056238.2|ensembl:ENSG00000149313(gene)|ensembl:ENST00000278618(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0008897"(holo-[acyl-carrier-protein] synthase activity)|go:"GO:0015939"(pantothenate metabolic process)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008278(4'-phosphopantetheinyl transferase)|interpro:IPR037143|rcsb pdb:2BYD|rcsb pdb:2C43|rcsb pdb:2CG5|reactome:R-HSA-199220	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:0S9gDK0HeJ+8eoM5vHaJDW3THAY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BTX1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2552800|ensembl:ENSP00000360483|uniprotkb:Q9NVZ7|uniprotkb:Q9H9T6|uniprotkb:Q9NSG3|uniprotkb:Q9NSG4|uniprotkb:Q8NB76|uniprotkb:B4DHA3|uniprotkb:B4DQQ5|uniprotkb:G3XA81	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndc1_human(display_long)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:TMEM48(gene name synonym)|uniprotkb:Transmembrane protein 48(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001162023.1|refseq:NP_060557.3|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-170822|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|ensembl:ENSG00000058804(gene)|ensembl:ENST00000371429(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|interpro:IPR019049|mint:Q9BTX1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:0HbFqC4o16ELLTSUfqACs1BD05I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P63172	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1176455|uniprotkb:Q15763|ensembl:ENSP00000356056|uniprotkb:Q5VTU4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dylt1_human(display_long)|uniprotkb:T-complex testis-specific protein 1 homolog(gene name synonym)|uniprotkb:Protein CW-1(gene name synonym)|uniprotkb:DYNLT1(gene name)|psi-mi:DYNLT1(display_short)|uniprotkb:TCTEL1(gene name synonym)|uniprotkb:TCTEX1(gene name synonym)|uniprotkb:TCTEX-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006510.1|ensembl:ENSG00000146425(gene)|ensembl:ENST00000367089(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0019060"(intracellular transport of viral protein in host cell)|go:"GO:0030027"(lamellipodium)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043657"(host cell)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051301"(cell division)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061564"(axon development)|go:"GO:0075521"(microtubule-dependent intracellular transport of viral material towards nucleus)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005334(Tctex-1)|interpro:IPR038586|rcsb pdb:5JPW|reactome:R-HSA-6798695|go:"GO:0005881"(cytoplasmic microtubule)|dip:DIP-35251N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RKVyHgf4iNjcY6GfLdIukFOFE+s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P56589	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-594885|uniprotkb:Q6FGP5|ensembl:ENSP00000356563	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pex3_human(display_long)|uniprotkb:Peroxisomal assembly protein PEX3(gene name synonym)|uniprotkb:PEX3(gene name)|psi-mi:PEX3(display_short)|uniprotkb:Peroxin-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003621.1|ensembl:ENSG00000034693(gene)|ensembl:ENST00000367591(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032994"(protein-lipid complex)|go:"GO:0045046"(protein import into peroxisome membrane)|interpro:IPR006966(Peroxin-3)|rcsb pdb:3AJB|rcsb pdb:3MK4|reactome:R-HSA-1369062|reactome:R-HSA-9603798	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:zB+V5tVREEww2DOugIl6YVsUqdM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y2H6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2810266|uniprotkb:Q6EVH4|uniprotkb:Q6N020|uniprotkb:B4DYG1|uniprotkb:Q5JVF8|uniprotkb:Q5HYC9|uniprotkb:Q6ZME4|uniprotkb:Q6P9D5|uniprotkb:Q6EVH3|uniprotkb:Q5JVF9|uniprotkb:Q9H1W1|ensembl:ENSP00000417257|ensembl:ENSP00000441831	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:fnd3a_human(display_long)|uniprotkb:FNDC3A(gene name)|psi-mi:FNDC3A(display_short)|uniprotkb:FNDC3(gene name synonym)|uniprotkb:HUGO(gene name synonym)|uniprotkb:KIAA0970(gene name synonym)|uniprotkb:Human gene expressed in odontoblasts(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_016875929.1|refseq:XP_016875930.1|refseq:XP_016875931.1|refseq:NP_001073141.1|refseq:NP_055738.3|refseq:XP_011533299.1|ensembl:ENSG00000102531(gene)|ensembl:ENST00000492622(transcript)|ensembl:ENST00000541916(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q9Y2H6|rcsb pdb:1WK0|rcsb pdb:1X3D|rcsb pdb:1X4X|rcsb pdb:1X5X|rcsb pdb:2CRM|rcsb pdb:2CRZ|go:"GO:0016021"(integral component of membrane)|refseq:NP_001265367.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:7gFZgxAfa590PH85SnEF3oeSNSI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BRT8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1054417|uniprotkb:A2RU55|uniprotkb:Q49AJ1|uniprotkb:Q5VVK2|uniprotkb:Q6VBU6|uniprotkb:Q7Z5Z0|uniprotkb:Q7Z652|uniprotkb:Q9BY38|uniprotkb:Q9NYD0|uniprotkb:B0AZR4|uniprotkb:A8K3N3|ensembl:ENSP00000348915|ensembl:ENSP00000366617	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cbwd1_human(display_long)|uniprotkb:Cobalamin synthase W domain-containing protein 1(gene name synonym)|uniprotkb:NPC-A-6 COBW domain-containing protein 1(gene name synonym)|uniprotkb:CBWD1(gene name)|psi-mi:CBWD1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001138827.1|refseq:NP_001138828.1|refseq:NP_060961.3|ensembl:ENSG00000172785(gene)|ensembl:ENST00000356521(transcript)|ensembl:ENST00000377400(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR003495("Cobalamin (vitamin B12) biosynthesis CobW-like")|interpro:IPR011629("Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal")|interpro:IPR027417|interpro:IPR036627	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DfI5wHHX8Rmk+dKB/oW+68ImtcE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BT22	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6268721|uniprotkb:B4DP08|ensembl:ENSP00000262374|uniprotkb:Q6UVZ9|uniprotkb:Q8N5Y4|uniprotkb:Q9P2Y2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:alg1_human(display_long)|uniprotkb:ALG1(gene name)|psi-mi:ALG1(display_short)|uniprotkb:HMAT1(gene name synonym)|uniprotkb:HMT1(gene name synonym)|uniprotkb:Asparagine-linked glycosylation protein 1 homolog(gene name synonym)|uniprotkb:Beta-1,4-mannosyltransferase(gene name synonym)|uniprotkb:"GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase"(gene name synonym)|uniprotkb:GDP-mannose-dolichol diphosphochitobiose mannosyltransferase(gene name synonym)|uniprotkb:Mannosyltransferase-1(gene name synonym)|uniprotkb:PSEC0061(orf name)|uniprotkb:UNQ861/PRO1870(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000033011(gene)|go:"GO:0000030"(mannosyltransferase activity)|go:"GO:0004578"(chitobiosyldiphosphodolichol beta-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR026051|mint:Q9BT22|reactome:R-HSA-446193|reactome:R-HSA-4549380|ensembl:ENST00000262374(transcript)|refseq:NP_061982.3|refseq:NP_001317433.1|refseq:XP_016878947.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ssuj2ltO7juusnd1BHWPqAsYdV09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q99956	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3906678|uniprotkb:D3DWU5|ensembl:ENSP00000345853|ensembl:ENSP00000359186	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dus9_human(display_long)|uniprotkb:DUSP9(gene name)|psi-mi:DUSP9(display_short)|uniprotkb:MKP4(gene name synonym)|uniprotkb:Mitogen-activated protein kinase phosphatase 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011529426.1|refseq:NP_001386.1|refseq:NP_001305432.1|ensembl:ENSG00000130829(gene)|ensembl:ENST00000342782(transcript)|ensembl:ENST00000370167(transcript)|go:"GO:0008330"(protein tyrosine/threonine phosphatase activity)|go:"GO:0017017"(MAP kinase tyrosine/serine/threonine phosphatase activity)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060420"(regulation of heart growth)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR008343(MAP kinase phosphatase)|interpro:IPR020422|interpro:IPR029021|interpro:IPR036873|mint:Q99956|rcsb pdb:2HXP|rcsb pdb:3LJ8|reactome:R-HSA-112409|go:"GO:0000165"(MAPK cascade)|reactome:R-HSA-5675221|reactome:R-HSA-9652817|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:djC92fivazm9x5q4xDTlKje/fzQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P39210	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943434|uniprotkb:D6W555|uniprotkb:Q53SY2|uniprotkb:Q96B08|ensembl:ENSP00000233545|ensembl:ENSP00000369383	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mpv17_human(display_long)|uniprotkb:MPV17(gene name)|psi-mi:MPV17(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002428.1|refseq:XP_005264383.1|ensembl:ENSG00000115204(gene)|ensembl:ENST00000233545(transcript)|ensembl:ENST00000380044(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015267"(channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042592"(homeostatic process)|go:"GO:0048839"(inner ear development)|go:"GO:1901858"(regulation of mitochondrial DNA metabolic process)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR007248(Mpv17/PMP22)|reactome:R-HSA-9033241	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:tCoKxAWz8XN4qBt0G9ROPWtEqu89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y287	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2866431|uniprotkb:Q5W0A3|uniprotkb:Q96B24|uniprotkb:Q9NYH1|ensembl:ENSP00000497221	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:itm2b_human(display_long)|uniprotkb:ITM2B(gene name)|psi-mi:ITM2B(display_short)|uniprotkb:BRI(gene name synonym)|uniprotkb:BRI2(gene name synonym)|uniprotkb:Protein E25B(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)|uniprotkb:Immature BRI2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_068839.1|ensembl:ENSG00000136156(gene)|ensembl:ENST00000647800(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|reactome:R-HSA-977225	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9mHhC4Z61CsmOsTh/1K9oj2NezA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P12532	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1050662|uniprotkb:Q0VAM3|uniprotkb:Q32NF6|uniprotkb:Q53FC4|uniprotkb:B4DIT8|uniprotkb:B7ZA09|ensembl:ENSP00000300283|ensembl:ENSP00000406577|ensembl:ENSP00000413165|ensembl:ENSP00000413255	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kcru_human(display_long)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:CKMT1A(gene name)|psi-mi:CKMT1A(display_short)|uniprotkb:CKMT(gene name synonym)|uniprotkb:CKMT1B(gene name)|psi-mi:CKMT1B(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001015001.1|refseq:NP_066270.1|refseq:NP_001308855.1|refseq:NP_001308856.1|refseq:NP_001308857.1|refseq:XP_016877858.1|refseq:XP_016877859.1|refseq:XP_011519496.1|refseq:XP_011519497.1|refseq:XP_011519498.1|refseq:XP_011519499.1|ensembl:ENSG00000223572(gene)|ensembl:ENSG00000237289(gene)|ensembl:ENST00000300283(transcript)|ensembl:ENST00000413453(transcript)|ensembl:ENST00000434505(transcript)|ensembl:ENST00000441322(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12532|rcsb pdb:1QK1|reactome:R-HSA-71288	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:2ZgqE1XmbPXtjVY6lIdy+e0bSdU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00560	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UHQ9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-953870|ensembl:ENSP00000356218|uniprotkb:A0PK21|uniprotkb:O95329|uniprotkb:Q53F73|uniprotkb:Q8NCL5|uniprotkb:Q9UHJ1|uniprotkb:B2R8E0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nb5r1_human(display_long)|uniprotkb:"NAD(P)H:quinone oxidoreductase type 3 polypeptide A2"(gene name synonym)|uniprotkb:Humb5R2(gene name synonym)|uniprotkb:CYB5R1(gene name)|psi-mi:CYB5R1(display_short)|uniprotkb:NQO3A2(gene name synonym)|uniprotkb:UNQ3049/PRO9865(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000159348(gene)|ensembl:ENST00000367249(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071949"(FAD binding)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|reactome:R-HSA-114608|reactome:R-HSA-1237044|go:"GO:0016020"(membrane)|refseq:NP_057327.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TOvJYSyfYu73Ac/SYjup+ABu74g9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q16650	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1047158|ensembl:ENSP00000374205|uniprotkb:Q14DC5|uniprotkb:Q53TH0|uniprotkb:B2R6G5|uniprotkb:Q56A81|uniprotkb:B0AZS4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tbr1_human(display_long)|uniprotkb:TES-56(gene name synonym)|uniprotkb:TBR1(gene name)|psi-mi:TBR1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006584.1|ensembl:ENSG00000136535(gene)|ensembl:ENST00000389554(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1902667"(regulation of axon guidance)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0010092"(specification of animal organ identity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021764"(amygdala development)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030902"(hindbrain development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR032385|interpro:IPR036960|mint:Q16650	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qD1euHkX/welvC2klFM95IiAiWE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15633	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-978581|uniprotkb:Q12878|ensembl:ENSP00000266987|uniprotkb:Q9BRY2|uniprotkb:Q8WY32|uniprotkb:Q8WY33	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:trbp2_human(display_long)|uniprotkb:Trans-activation-responsive RNA-binding protein(gene name synonym)|uniprotkb:TARBP2(gene name)|psi-mi:TARBP2(display_short)|uniprotkb:TRBP(gene name synonym)|uniprotkb:TAR RNA-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000139546(gene)|ensembl:ENST00000266987(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0016442"(RISC complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046782"(regulation of viral transcription)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090065"(regulation of production of siRNA involved in RNA interference)|go:"GO:1903798"(regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR028605|interpro:IPR044469|interpro:IPR044470|interpro:IPR044471|mint:Q15633|rcsb pdb:2CPN|rcsb pdb:3ADL|rcsb pdb:3LLH|rcsb pdb:4WYQ|go:"GO:0016604"(nuclear body)|rcsb pdb:5N8L|rcsb pdb:5N8M|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|rcsb pdb:6ZBK|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_004169.3|refseq:NP_599150.1|refseq:NP_599151.2|refseq:XP_005269171.1|refseq:XP_005269172.1|dip:DIP-29665N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:2pOFQwyM408mDl2bYsKEb1yhFrE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96ER3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-721193|uniprotkb:A6NH05|ensembl:ENSP00000432487	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:saal1_human(display_long)|uniprotkb:Synoviocyte proliferation-associated in collagen-induced arthritis protein 1(gene name synonym)|uniprotkb:SAAL1(gene name)|psi-mi:SAAL1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_612430.2|ensembl:ENSG00000166788(gene)|ensembl:ENST00000524803(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:1901647"(positive regulation of synoviocyte proliferation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/zDVy3k3FVjctiLf1XeIeWHL9BE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P51452	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1049755|uniprotkb:Q5U0J1|uniprotkb:D3DX45|ensembl:ENSP00000226004|uniprotkb:Q8IYJ9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dus3_human(display_long)|uniprotkb:Dual specificity protein phosphatase VHR(gene name synonym)|uniprotkb:DUSP3(gene name)|psi-mi:DUSP3(display_short)|uniprotkb:VHR(gene name synonym)|uniprotkb:Vaccinia H1-related phosphatase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004081.1|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050868"(negative regulation of T cell activation)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020405|interpro:IPR020422|interpro:IPR029021|rcsb pdb:1J4X|rcsb pdb:1VHR|rcsb pdb:3F81|reactome:R-HSA-202670|ensembl:ENSG00000108861(gene)|ensembl:ENST00000226004(transcript)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:1kqI9JZrOBsMIH4M2AoWBOmQPko9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NZT2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1044212|uniprotkb:O96029|uniprotkb:Q4VXW5|uniprotkb:Q96CM2|uniprotkb:Q9BQW1|uniprotkb:Q9H4H0|uniprotkb:Q9H7J5|uniprotkb:Q9NZT3|uniprotkb:Q9NZT4|ensembl:ENSP00000290291	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ogfr_human(display_long)|uniprotkb:OGFR(gene name)|psi-mi:OGFR(display_short)|uniprotkb:Zeta-type opioid receptor(gene name synonym)|uniprotkb:Protein 7-60(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_031372.2|ensembl:ENSG00000060491(gene)|ensembl:ENST00000290291(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR006757("Opioid growth factor receptor (OGFr) conserved region")|interpro:IPR006770(Opioid growth factor receptor repeat)|interpro:IPR039574|mint:Q9NZT2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:d2e2Qbj0DA9Dju9Qo7hy1picqbo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P27361	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-73995|uniprotkb:B0LPG3|uniprotkb:A8CZ58|uniprotkb:Q8NHX1|ensembl:ENSP00000263025	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mk03_human(display_long)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:MAPK3(gene name)|psi-mi:MAPK3(display_short)|uniprotkb:ERK1(gene name synonym)|uniprotkb:PRKM3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001035145.1|refseq:NP_001103361.1|refseq:NP_002737.2|dip:DIP-30985N|ensembl:ENSG00000102882(gene)|ensembl:ENST00000263025(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P27361|rcsb pdb:2ZOQ|rcsb pdb:4QTB|rcsb pdb:6GES|reactome:R-HSA-110056|reactome:R-HSA-112409|reactome:R-HSA-1169408|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-73728|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:PGxmRMz0kOsJTfdn21FBiF33YwI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:K7ES11	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943432|ensembl:ENSP00000468498	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:k7es11_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000175931(gene)|ensembl:ENST00000587127(transcript)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:tZsKdtXT7l4IKEZo6frjhBGN8ME9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:K7EIG1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-12508166|ensembl:ENSP00000464732	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:k7eig1_human(display_long)|uniprotkb:CLUH(gene name)|psi-mi:CLUH(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000132361(gene)|ensembl:ENST00000575014(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023231|interpro:IPR025697|interpro:IPR027523|interpro:IPR028275|interpro:IPR033646	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:944DSX7wGR6xTSvKXicRBKVeDrs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q99871	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-395719|uniprotkb:Q96HS8|uniprotkb:Q9NP54|uniprotkb:D3DWT9|intact:EBI-2558192|uniprotkb:B4DUH6|uniprotkb:Q9UFH9|ensembl:ENSP00000359230	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:haus7_human(display_long)|uniprotkb:HAUS7(gene name)|psi-mi:HAUS7(display_short)|uniprotkb:26S proteasome-associated UCH37-interacting protein 1(gene name synonym)|uniprotkb:X-linked protein STS1769(gene name synonym)|uniprotkb:UIP1(gene name synonym)|uniprotkb:UCHL5IP(gene name synonym)|uniprotkb:UCHL5-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_059988.3|dip:DIP-32974N|ensembl:ENSG00000213397(gene)|ensembl:ENST00000370211(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0031996"(thioesterase binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR029711|mint:Q99871|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:nDQXUt43VCTD0vyH0M8OAsGJbEY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P30279	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-748789|uniprotkb:Q13955|uniprotkb:Q5U035|uniprotkb:A8K531|ensembl:ENSP00000261254|ensembl:ENSP00000502597|ensembl:ENSP00000502654	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ccnd2_human(display_long)|uniprotkb:CCND2(gene name)|psi-mi:CCND2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001750.1|ensembl:ENSG00000118971(gene)|ensembl:ENST00000261254(transcript)|ensembl:ENST00000676279(transcript)|ensembl:ENST00000676411(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015451(Cyclin D)|interpro:IPR036915|interpro:IPR039361|mint:P30279|rcsb pdb:6EI2|reactome:R-HSA-69231|reactome:R-HSA-8934593|reactome:R-HSA-9661069|go:"GO:0005829"(cytosol)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|dip:DIP-178N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:7DtKJiw07/E5uNvUagbYbcAo7kM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75352	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1046501|ensembl:ENSP00000250124|uniprotkb:B3KQP1|uniprotkb:Q9BUU8|uniprotkb:B4DT74	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mpu1_human(display_long)|uniprotkb:Suppressor of Lec15 and Lec35 glycosylation mutation homolog(gene name synonym)|uniprotkb:MPDU1(gene name)|psi-mi:MPDU1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000129255(gene)|ensembl:ENST00000250124(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0009312"(oligosaccharide biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006603(Cystinosin/ERS1p repeat)|interpro:IPR016817(Mannose-P-dolichol utilization defect 1 protein)|reactome:R-HSA-446193|reactome:R-HSA-4687000|refseq:NP_004861.2|refseq:NP_001317002.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fTQ9idHmko5H6UYo6izQewwjR7U9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15139	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1181072|uniprotkb:A6NL64|uniprotkb:B2RAF6|ensembl:ENSP00000333568|ensembl:ENSP00000482645	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kpcd1_human(display_long)|uniprotkb:nPKC-D1(gene name synonym)|uniprotkb:Protein kinase D(gene name synonym)|uniprotkb:Protein kinase C mu type(gene name synonym)|uniprotkb:nPKC-mu(gene name synonym)|uniprotkb:PRKD1(gene name)|psi-mi:PRKD1(display_short)|uniprotkb:PKD(gene name synonym)|uniprotkb:PKD1(gene name synonym)|uniprotkb:PRKCM(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002733.2|ensembl:ENSG00000184304(gene)|ensembl:ENST00000331968(transcript)|ensembl:ENST00000616995(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0089700"(protein kinase D signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901727"(positive regulation of histone deacetylase activity)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001044"(regulation of integrin-mediated signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015727(Protein kinase C mu-related)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0006915"(apoptotic process)|reactome:R-HSA-1660661|interpro:IPR020454|dip:DIP-38481N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:L92XaEb6RJRv/HwB9Z56hiEl3jI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13308	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2803245|uniprotkb:Q8NFA6|uniprotkb:Q5T650|uniprotkb:Q8NFA8|uniprotkb:Q13417|uniprotkb:Q6IQ54|uniprotkb:Q8NFA5|uniprotkb:Q8NFA7|uniprotkb:A8K974|uniprotkb:B7Z477|uniprotkb:E9PFZ5|ensembl:ENSP00000230419	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ptk7_human(display_long)|uniprotkb:CCK4(gene name synonym)|uniprotkb:Colon carcinoma kinase 4(gene name synonym)|uniprotkb:Protein-tyrosine kinase 7(gene name synonym)|uniprotkb:PTK7(gene name)|psi-mi:PTK7(display_short)|uniprotkb:Pseudo tyrosine kinase receptor 7(gene name synonym)|uniprotkb:Tyrosine-protein kinase-like 7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001257327.1|refseq:NP_002812.2|refseq:NP_690619.1|refseq:NP_690620.1|refseq:NP_690621.1|ensembl:ENSG00000112655(gene)|ensembl:ENST00000230419(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001822"(kidney development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003401"(axis elongation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042060"(wound healing)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060026"(convergent extension)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1904929"(coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q13308|rcsb pdb:6VG3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:O4L3LFD0WvN1hDb1abqVBbW1gis9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BQ04	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-715531|uniprotkb:B3KT83|ensembl:ENSP00000310471|ensembl:ENSP00000433071	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rbm4b_human(display_long)|uniprotkb:RNA-binding motif protein 4B(gene name synonym)|uniprotkb:RNA-binding protein 30(gene name synonym)|uniprotkb:RNA-binding motif protein 30(gene name synonym)|uniprotkb:RBM4B(gene name)|psi-mi:RBM4B(display_short)|uniprotkb:RBM30(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001273064.1|refseq:NP_113680.1|refseq:XP_011543599.1|ensembl:ENSG00000173914(gene)|ensembl:ENST00000310046(transcript)|ensembl:ENST00000525754(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979|mint:Q9BQ04|rcsb pdb:2DGT|refseq:XP_016873891.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3EzHpurWDZlPeaLV0EFAAAo2MO09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6Y1H2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-530257|ensembl:ENSP00000373153	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hacd2_human(display_long)|uniprotkb:HACD2(gene name)|psi-mi:HACD2(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 2(gene name synonym)|uniprotkb:PTPLB(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like member B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_940684.1|ensembl:ENSG00000206527(gene)|ensembl:ENST00000383657(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0080023"(3R-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|reactome:R-HSA-75876	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:GBsqZyiJ8Tc3IuibyZcz8MOnlao9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43237	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-715294|uniprotkb:Q8TAT3|uniprotkb:A8K6V1|uniprotkb:B4DZP4|ensembl:ENSP00000258198	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dc1l2_human(display_long)|uniprotkb:Dynein light intermediate chain 2, cytosolic(gene name synonym)|uniprotkb:LIC53/55(gene name synonym)|uniprotkb:DYNC1LI2(gene name)|psi-mi:DYNC1LI2(display_short)|uniprotkb:LIC2(gene name synonym)|uniprotkb:DNCLI2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006132.1|refseq:NP_001273086.1|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0051642"(centrosome localization)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|go:"GO:0000776"(kinetochore)|go:"GO:0005524"(ATP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|rcsb pdb:6F1T|rcsb pdb:6F1Y|rcsb pdb:6F38|rcsb pdb:6F3A|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|ensembl:ENSG00000135720(gene)|ensembl:ENST00000258198(transcript)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:WUEd3zgPhcKEe10gtoJ+okX8Zps9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q2TB90	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5460752|uniprotkb:B5MDN9|uniprotkb:Q2TB91|uniprotkb:Q5VTC7|uniprotkb:Q7Z373|uniprotkb:Q8WU37|uniprotkb:Q96EH2|uniprotkb:Q9H5Y9|ensembl:ENSP00000346643	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hkdc1_human(display_long)|uniprotkb:HKDC1(gene name)|psi-mi:HKDC1(display_short)|uniprotkb:Hexokinase domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_079406.3|ensembl:ENSG00000156510(gene)|ensembl:ENST00000354624(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0019318"(hexose metabolic process)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:Q2TB90	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qJkekQnFg0rXMtIKJK8Hsy4FWOA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96AQ6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6PK18	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943430|uniprotkb:C9JDC8|uniprotkb:Q8IZ37|uniprotkb:Q9H6J2|ensembl:ENSP00000320116	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ogfd3_human(display_long)|uniprotkb:OGFOD3(gene name)|psi-mi:OGFOD3(display_short)|uniprotkb:C17orf101(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_078924.1|refseq:NP_787098.3|ensembl:ENSG00000181396(gene)|ensembl:ENST00000313056(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016705"(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR039210	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ftFNtqMkXFUIo+2mgK0tPxeg3ww9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75718	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2515576|ensembl:ENSP00000323696|uniprotkb:B2RBL6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:crtap_human(display_long)|uniprotkb:CRTAP(gene name)|psi-mi:CRTAP(display_short)|uniprotkb:CASP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000170275(gene)|ensembl:ENST00000320954(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007283"(spermatogenesis)|go:"GO:0018400"(peptidyl-proline hydroxylation to 3-hydroxy-L-proline)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901874"(negative regulation of post-translational protein modification)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033212|mint:O75718|reactome:R-HSA-1650814|refseq:NP_006362.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:7rtGL+UxGVyDTmnJagIzXaUziIw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P35610	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6621955|ensembl:ENSP00000356591|uniprotkb:A6NC40|uniprotkb:A8K3P4|uniprotkb:A9Z1V7|uniprotkb:B4DU95|uniprotkb:Q5T0X4|uniprotkb:Q8N1E4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:soat1_human(display_long)|uniprotkb:SOAT1(gene name)|psi-mi:SOAT1(display_short)|uniprotkb:ACACT(gene name synonym)|uniprotkb:ACACT1(gene name synonym)|uniprotkb:ACAT(gene name synonym)|uniprotkb:ACAT1(gene name synonym)|uniprotkb:SOAT(gene name synonym)|uniprotkb:STAT(gene name synonym)|uniprotkb:"Acyl-coenzyme A:cholesterol acyltransferase 1"(gene name synonym)|uniprotkb:Cholesterol acyltransferase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0010878"(cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0034736"(cholesterol O-acyltransferase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|ensembl:ENSG00000057252(gene)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|interpro:IPR030687|mint:P35610|rcsb pdb:6L47|rcsb pdb:6L48|rcsb pdb:6P2J|rcsb pdb:6P2P|rcsb pdb:6VUM|reactome:R-HSA-8964038|ensembl:ENST00000367619(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004772"(sterol O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010742"(macrophage derived foam cell differentiation)|refseq:XP_011508213.1|refseq:NP_001239440.1|refseq:NP_001239441.1|refseq:NP_003092.4	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:jX8d8x9ZYOdpE2Vg+C5ECuX9zQQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q14651	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1047196|uniprotkb:D3DNG3|uniprotkb:A8K2Q1|uniprotkb:Q8NEG6|ensembl:ENSP00000336831|ensembl:ENSP00000387890|ensembl:ENSP00000418700	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:plsi_human(display_long)|uniprotkb:Intestine-specific plastin(gene name synonym)|uniprotkb:PLS1(gene name)|psi-mi:PLS1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	interpro:IPR018247|interpro:IPR011992(EF-Hand type)|interpro:IPR030235|interpro:IPR036872|interpro:IPR039959|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001138791.1|refseq:NP_001165783.1|refseq:NP_002661.2|refseq:XP_011511202.1|refseq:XP_011511203.1|refseq:XP_011511205.1|ensembl:ENSG00000120756(gene)|ensembl:ENST00000337777(transcript)|ensembl:ENST00000457734(transcript)|ensembl:ENST00000497002(transcript)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005903"(brush border)|go:"GO:0032420"(stereocilium)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060121"(vestibular receptor cell stereocilium organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990357"(terminal web)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|refseq:XP_006713723.1|refseq:XP_016862115.1|refseq:XP_016862116.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:jDBbZOh8WmNZbAhnOmxcqb6fGvc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HBH1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5460681|uniprotkb:Q8WUN6|ensembl:ENSP00000288022	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:defm_human(display_long)|uniprotkb:PDF(gene name)|psi-mi:PDF(display_short)|uniprotkb:PDF1A(gene name synonym)|uniprotkb:Polypeptide deformylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_071736.1|ensembl:ENST00000288022(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0018206"(peptidyl-methionine modification)|ensembl:ENSG00000258429(gene)|go:"GO:0031365"(N-terminal protein amino acid modification)|go:"GO:0042586"(peptide deformylase activity)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR023635|interpro:IPR036821|rcsb pdb:3G5K|rcsb pdb:3G5P	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:StM3o3nhBlrCad9VRPWUt48jgaM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q86UL3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3925330|uniprotkb:Q86V89|ensembl:ENSP00000380184|uniprotkb:Q2TU73	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gpat4_human(display_long)|uniprotkb:GPAT4(gene name)|psi-mi:GPAT4(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 6(gene name synonym)|uniprotkb:AGPAT6(gene name synonym)|uniprotkb:"Acyl-CoA:glycerol-3-phosphate acyltransferase 4"(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase zeta(gene name synonym)|uniprotkb:TSARG7(gene name synonym)|uniprotkb:Testis spermatogenesis apoptosis-related protein 7(gene name synonym)|uniprotkb:UNQ551/PRO1108(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011542694.1|refseq:XP_011542695.1|refseq:XP_011542696.1|refseq:NP_848934.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0007595"(lactation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0102420"("sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity")|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|reactome:R-HSA-1483166|ensembl:ENSG00000158669(gene)|ensembl:ENST00000396987(transcript)|go:"GO:0002071"(glandular epithelial cell maturation)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0004366"(glycerol-3-phosphate O-acyltransferase activity)|refseq:XP_016868531.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:0j/B1lxhVshCx6yA7HNCsemsuD49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NWS8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4401316|uniprotkb:A8K8H4|uniprotkb:Q0VDG6|uniprotkb:Q5SZ48|uniprotkb:Q5SZ83|uniprotkb:Q6NSC5|uniprotkb:Q96EN7|ensembl:ENSP00000412708|ensembl:ENSP00000507984	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rmnd1_human(display_long)|uniprotkb:RMND1(gene name)|psi-mi:RMND1(display_short)|uniprotkb:C6orf96(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060379.2|refseq:XP_005267097.1|refseq:NP_001258866.1|refseq:XP_016866477.1|ensembl:ENSG00000155906(gene)|ensembl:ENST00000444024(transcript)|ensembl:ENST00000683724(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006412"(translation)|go:"GO:0070131"(positive regulation of mitochondrial translation)|interpro:IPR003734(Protein of unknown function DUF155)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:yCKKEY1X6dSYbAiTBhOwnPkkxyk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15070	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3917688|uniprotkb:B4DPA2|ensembl:ENSP00000350740	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:oxa1l_human(display_long)|uniprotkb:OXA1L(gene name)|psi-mi:OXA1L(display_short)|uniprotkb:Hsa(gene name synonym)|uniprotkb:OXA1Hs(gene name synonym)|uniprotkb:Oxidase assembly 1-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005006.3|ensembl:ENSG00000155463(gene)|ensembl:ENST00000358043(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009060"(aerobic respiration)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032977"(membrane insertase activity)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR001708(60 kDa inner membrane insertion protein)|interpro:IPR028055|mint:Q15070|rcsb pdb:6ZM5|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:1C8BWezMWHLLnmHl7vOik3WJmKY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q86UT6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3893071|uniprotkb:A8K6Q1|uniprotkb:B3KPK2|uniprotkb:B3KTA2|uniprotkb:Q7RTR3|uniprotkb:Q96D51|uniprotkb:Q9H724|ensembl:ENSP00000292199|ensembl:ENSP00000386851|ensembl:ENSP00000386858|ensembl:ENSP00000387334	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nlrx1_human(display_long)|uniprotkb:NLRX1(gene name)|psi-mi:NLRX1(display_short)|uniprotkb:NOD26(gene name synonym)|uniprotkb:NOD5(gene name synonym)|uniprotkb:NOD9(gene name synonym)|uniprotkb:Caterpiller protein 11.3(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 26(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 5(gene name synonym)|uniprotkb:Nucleotide-binding oligomerization domain protein 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_006718967.1|refseq:XP_011541282.1|refseq:NP_078894.2|dip:DIP-60637N|refseq:NP_001269072.1|refseq:NP_001269073.1|refseq:NP_001269287.1|refseq:XP_005271726.1|ensembl:ENSG00000160703(gene)|ensembl:ENST00000292199(transcript)|ensembl:ENST00000409109(transcript)|ensembl:ENST00000409265(transcript)|ensembl:ENST00000409991(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050728"(negative regulation of inflammatory response)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR032675|rcsb pdb:3UN9|reactome:R-HSA-168928|reactome:R-HSA-936440|go:"GO:0030054"(cell junction)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:w+BOLVATt2ey/lEP6RY9zP2q/gc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NX20	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2560190|uniprotkb:Q9HB70|uniprotkb:Q9BYD0|ensembl:ENSP00000300151	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rm16_human(display_long)|uniprotkb:MRPL16(gene name)|psi-mi:MRPL16(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL16m(gene name synonym)|uniprotkb:PNAS-111(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060310.1|ensembl:ENSG00000166902(gene)|ensembl:ENST00000300151(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000114(Ribosomal protein L16)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR036920|mint:Q9NX20|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5ngQm8RUtN0SGgxJN2mGtWKhHMU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P23921	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q99720	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3248663|ensembl:ENSP00000277010|uniprotkb:O00673|uniprotkb:Q2TSD1|uniprotkb:Q7Z653|uniprotkb:Q153Z1|uniprotkb:Q53GN2|uniprotkb:Q9NYX0|uniprotkb:O00725|uniprotkb:Q8N7H3|uniprotkb:Q0Z9W6|uniprotkb:D3DRM7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sgmr1_human(display_long)|uniprotkb:SIGMAR1(gene name)|psi-mi:SIGMAR1(display_short)|uniprotkb:OPRS1(gene name synonym)|uniprotkb:SRBP(gene name synonym)|uniprotkb:Aging-associated gene 8 protein(gene name synonym)|uniprotkb:SR31747-binding protein(gene name synonym)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:AAG8(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000147955(gene)|ensembl:ENST00000277010(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)|mint:Q99720|rcsb pdb:5HK1|rcsb pdb:5HK2|rcsb pdb:6DJZ|rcsb pdb:6DK0|rcsb pdb:6DK1|reactome:R-HSA-9679191|refseq:NP_005857.1|refseq:NP_671513.1|refseq:NP_001269134.1|refseq:NP_001269135.1|refseq:NP_001269136.1|refseq:NP_001269137.1|refseq:NP_001269138.1|dip:DIP-61974N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:iEc1O6PXikkaE/0zk0A5Z7fMIZ49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P05067	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-77613|uniprotkb:P09000|uniprotkb:P78438|uniprotkb:Q13764|uniprotkb:Q13778|uniprotkb:Q13793|ensembl:ENSP00000284981|intact:EBI-28985182|uniprotkb:Q6GSC0|uniprotkb:Q8WZ99|uniprotkb:Q9UC33|uniprotkb:Q9UCC8|uniprotkb:Q9UCD1|uniprotkb:Q9UQ58|uniprotkb:Q16011|uniprotkb:Q16014|uniprotkb:Q16019|uniprotkb:Q16020|uniprotkb:Q9BT38|uniprotkb:Q9UCA9|uniprotkb:Q9UCB6|uniprotkb:B4DII8|uniprotkb:B2R5V1|uniprotkb:D3DSD1|uniprotkb:D3DSD2|uniprotkb:D3DSD3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:a4_human(display_long)|uniprotkb:APP(gene name)|psi-mi:APP(display_short)|uniprotkb:A4(gene name synonym)|uniprotkb:AD1(gene name synonym)|uniprotkb:Alzheimer disease amyloid protein(gene name synonym)|uniprotkb:ABPP(gene name synonym)|uniprotkb:PreA4(gene name synonym)|uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)|uniprotkb:Protease nexin-II(gene name synonym)|uniprotkb:APPI(gene name synonym)|uniprotkb:Amyloid precursor protein(gene name synonym)|uniprotkb:Amyloid-beta A4 protein(gene name synonym)|uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)|uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0097645"(amylin binding)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0106003"(amyloid-beta complex)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:1900122"(positive regulation of receptor binding)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903048"(regulation of acetylcholine-gated cation channel activity)|go:"GO:1903223"(positive regulation of oxidative stress-induced neuron death)|go:"GO:1903523"(negative regulation of blood circulation)|go:"GO:1904022"(positive regulation of G protein-coupled receptor internalization)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043235"(receptor complex)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044304"(main axon)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENST00000346798(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|ensembl:ENSG00000142192(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001878"(response to yeast)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001967"(suckling behavior)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007155"(cell adhesion)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007611"(learning or memory)|go:"GO:0006897"(endocytosis)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0009987"(cellular process)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048669"(collateral sprouting in absence of injury)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050808"(synapse organization)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050867"(positive regulation of cell activation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050890"(cognition)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0010823"(negative regulation of mitochondrion organization)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014005"(microglia development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016358"(dendrite development)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0019899"(enzyme binding)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030424"(axon)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0030900"(forebrain development)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031175"(neuron projection development)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031904"(endosome lumen)|go:"GO:0051233"(spindle midzone)|go:"GO:0061903"(positive regulation of 1-phosphatidylinositol-3-kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071874"(cellular response to norepinephrine stimulus)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097449"(astrocyte projection)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051563"(smooth endoplasmic reticulum calcium ion homeostasis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055037"(recycling endosome)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:1904399"(heparan sulfate binding)|rcsb pdb:2LZ4|rcsb pdb:2M4J|rcsb pdb:2M9R|rcsb pdb:2M9S|rcsb pdb:2MGT|rcsb pdb:2MJ1|rcsb pdb:2MPZ|rcsb pdb:2MVX|rcsb pdb:2MXU|rcsb pdb:2NAO|interpro:IPR036880|interpro:IPR037071|rcsb pdb:2OTK|rcsb pdb:2R0W|rcsb pdb:2WK3|rcsb pdb:2Y29|mint:P05067|rcsb pdb:1AAP|rcsb pdb:1AMB|rcsb pdb:1AMC|rcsb pdb:1AML|rcsb pdb:1BA4|rcsb pdb:1BA6|rcsb pdb:1BJB|rcsb pdb:1BJC|rcsb pdb:1BRC|rcsb pdb:1CA0|rcsb pdb:1HZ3|rcsb pdb:1IYT|rcsb pdb:1MWP|rcsb pdb:1OWT|rcsb pdb:1QCM|rcsb pdb:1QWP|rcsb pdb:1QXC|rcsb pdb:1QYT|rcsb pdb:1TAW|rcsb pdb:1TKN|rcsb pdb:1UO7|rcsb pdb:1UO8|rcsb pdb:1UOA|rcsb pdb:1UOI|rcsb pdb:1X11|rcsb pdb:1Z0Q|rcsb pdb:1ZE7|rcsb pdb:1ZE9|rcsb pdb:1ZJD|rcsb pdb:2BEG|rcsb pdb:2BOM|rcsb pdb:2BP4|rcsb pdb:2FJZ|rcsb pdb:2FK1|rcsb pdb:2FK2|rcsb pdb:2FK3|rcsb pdb:2FKL|rcsb pdb:2FMA|rcsb pdb:2G47|rcsb pdb:2IPU|rcsb pdb:2LFM|rcsb pdb:2LLM|rcsb pdb:2LMN|rcsb pdb:2LMO|rcsb pdb:2LMP|rcsb pdb:2LMQ|rcsb pdb:2LNQ|rcsb pdb:2LOH|rcsb pdb:2LP1|rcsb pdb:2LZ3|rcsb pdb:2Y2A|rcsb pdb:2Y3J|rcsb pdb:2Y3K|rcsb pdb:2Y3L|rcsb pdb:3AYU|rcsb pdb:3BAE|rcsb pdb:3BKJ|rcsb pdb:3DXC|rcsb pdb:3DXD|rcsb pdb:3DXE|rcsb pdb:3GCI|rcsb pdb:3IFL|rcsb pdb:3IFN|rcsb pdb:3IFO|rcsb pdb:3IFP|rcsb pdb:3JQ5|rcsb pdb:3JQL|rcsb pdb:3JTI|rcsb pdb:3KTM|rcsb pdb:3L33|go:"GO:1904472"(positive regulation of endothelin production)|go:"GO:1904591"(positive regulation of protein import)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905893"(positive regulation of cellular response to thapsigargin)|go:"GO:1905896"(positive regulation of cellular response to tunicamycin)|go:"GO:1905898"(positive regulation of response to endoplasmic reticulum stress)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:1905945"(regulation of response to calcium ion)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990761"(growth cone lamellipodium)|go:"GO:1990777"(lipoprotein particle)|go:"GO:1990812"(growth cone filopodium)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000406"(positive regulation of T cell migration)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013803(Amyloidogenic glycoprotein, amyloid-beta peptide)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR020901|interpro:IPR024329|interpro:IPR028866|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|rcsb pdb:5HOY|rcsb pdb:5KK3|rcsb pdb:5LFY|rcsb pdb:5LV0|rcsb pdb:5MY4|rcsb pdb:5MYO|rcsb pdb:5MYX|rcsb pdb:5ONP|rcsb pdb:5ONQ|rcsb pdb:5OQV|rcsb pdb:5TXD|rcsb pdb:5VOS|rcsb pdb:5VZY|rcsb pdb:5W3P|rcsb pdb:6CO3|rcsb pdb:6GFI|rcsb pdb:6ITU|rcsb pdb:6IYC|rcsb pdb:6NB9|rcsb pdb:6O4J|rcsb pdb:6OC9|rcsb pdb:6OIZ|rcsb pdb:6RHY|rcsb pdb:6SHS|rcsb pdb:6SZF|rcsb pdb:6TI5|rcsb pdb:6TI6|rcsb pdb:6TI7|rcsb pdb:6W0O|rcsb pdb:6WXM|rcsb pdb:6YHF|rcsb pdb:6YHI|rcsb pdb:6YHO|rcsb pdb:6YHP|rcsb pdb:6YHX|rcsb pdb:7B3J|rcsb pdb:7B3K|rcsb pdb:7JXN|rcsb pdb:7JXO|rcsb pdb:7O1Q|reactome:R-HSA-114608|reactome:R-HSA-3000178|reactome:R-HSA-381426|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-432720|reactome:R-HSA-444473|reactome:R-HSA-445989|reactome:R-HSA-844456|reactome:R-HSA-879415|reactome:R-HSA-8862803|reactome:R-HSA-8957275|reactome:R-HSA-933542|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-977225|rcsb pdb:5AMB|rcsb pdb:5BUO|rcsb pdb:5C67|rcsb pdb:5CSZ|rcsb pdb:5HOW|rcsb pdb:5HOX|rcsb pdb:3L81|rcsb pdb:3MOQ|rcsb pdb:3MXC|rcsb pdb:3MXY|rcsb pdb:3NYJ|rcsb pdb:3NYL|rcsb pdb:3OVJ|rcsb pdb:3OW9|rcsb pdb:3PZZ|rcsb pdb:3Q2X|rcsb pdb:3SV1|rcsb pdb:3U0T|rcsb pdb:3UMH|rcsb pdb:3UMI|rcsb pdb:3UMK|rcsb pdb:4HIX|rcsb pdb:4JFN|rcsb pdb:4M1C|rcsb pdb:4MDR|rcsb pdb:4MVI|rcsb pdb:4MVK|rcsb pdb:4MVL|rcsb pdb:4NGE|rcsb pdb:4OJF|rcsb pdb:4ONF|rcsb pdb:4ONG|rcsb pdb:4PQD|rcsb pdb:4PWQ|rcsb pdb:4XXD|rcsb pdb:5AEF|rcsb pdb:5AM8|refseq:NP_000475.1|refseq:NP_001129601.1|refseq:NP_001129602.1|refseq:NP_001191230.1|refseq:NP_001191231.1|refseq:NP_001191232.1|refseq:NP_958816.1|refseq:NP_958817.1|ensembl:ENSP00000284981|ensembl:ENST00000348990|ensembl:ENSP00000345463|ensembl:ENST00000354192|ensembl:ENSP00000346129|ensembl:ENST00000357903|ensembl:ENSP00000350578|ensembl:ENST00000358918|ensembl:ENSP00000351796|ensembl:ENST00000440126|ensembl:ENSP00000387483|refseq:NP_001129488.1|refseq:NP_001129603.1|dip:DIP-574N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:HatR8w8+mNjtjr7s5+bAwaStpmk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P49247	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-744831|uniprotkb:Q541P9|uniprotkb:Q96BJ6|ensembl:ENSP00000283646	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rpia_human(display_long)|uniprotkb:Phosphoriboisomerase(gene name synonym)|uniprotkb:RPIA(gene name)|psi-mi:RPIA(display_short)|uniprotkb:RPI(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_653164.2|ensembl:ENSG00000153574(gene)|ensembl:ENST00000283646(transcript)|go:"GO:0004751"(ribose-5-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006014"(D-ribose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR004788(Ribose 5-phosphate isomerase)|interpro:IPR020672|interpro:IPR037171|mint:P49247|reactome:R-HSA-5659996|reactome:R-HSA-6791461|reactome:R-HSA-71336	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:gddu0Xp/dx4JwbFMs50pQCvvbws9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NQC7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q14168	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3046657|uniprotkb:Q53ES9|uniprotkb:Q9BQJ2|uniprotkb:Q5CZB9|uniprotkb:E7EX01|uniprotkb:B4DGE9|uniprotkb:B4DRJ0|uniprotkb:B7Z3G8|uniprotkb:E7EV80|uniprotkb:E7EV91	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mpp2_human(display_long)|uniprotkb:MPP2(gene name)|psi-mi:MPP2(display_short)|uniprotkb:DLG2(gene name synonym)|uniprotkb:Discs large homolog 2(gene name synonym)|uniprotkb:Protein MPP2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005365.4|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0014069"(postsynaptic density)|go:"GO:0032590"(dendrite membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|rcsb pdb:2E7K|refseq:NP_001265305.2|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001452(Src homology-3)|interpro:IPR027417|refseq:NP_001265299.1|refseq:NP_001265300.1|refseq:NP_001265301.1|refseq:NP_001265302.1|refseq:NP_001265303.1|refseq:NP_001265304.1|refseq:NP_001265310.1|interpro:IPR035602|mint:Q14168|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:V/6k8hS86wWuXs+iU37my9MOYtc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P30085	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1053384|uniprotkb:Q53GB7|uniprotkb:Q5SVZ0|uniprotkb:Q96C07|uniprotkb:Q9UBQ8|uniprotkb:Q9UIA2|uniprotkb:B4DPU7|uniprotkb:E9PGI8|intact:EBI-14470672|uniprotkb:B2R6S5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kcy_human(display_long)|uniprotkb:CMPK(gene name synonym)|uniprotkb:Deoxycytidylate kinase(gene name synonym)|uniprotkb:Uridine monophosphate/cytidine monophosphate kinase(gene name synonym)|uniprotkb:CMPK1(gene name)|psi-mi:CMPK1(display_short)|uniprotkb:CMK(gene name synonym)|uniprotkb:UCK(gene name synonym)|uniprotkb:UMK(gene name synonym)|uniprotkb:UMPK(gene name synonym)|uniprotkb:Nucleoside-diphosphate kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	interpro:IPR027417|refseq:NP_001129612.1|refseq:NP_057392.1|interpro:IPR000850(Adenylate kinase)|interpro:IPR006266(UMP-CMP kinase)|go:"GO:0004127"(cytidylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004849"(uridine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006225"(UDP biosynthetic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0009220"(pyrimidine ribonucleotide biosynthetic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0033862"(UMP kinase activity)|go:"GO:0036430"(CMP kinase activity)|go:"GO:0036431"(dCMP kinase activity)|go:"GO:0046705"(CDP biosynthetic process)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1TEV|rcsb pdb:7E9V|reactome:R-HSA-499943|interpro:IPR033690|mint:P30085	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:NUl0+m77fVbeIbhsbRekyl45k0w9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NC60	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-717871|uniprotkb:Q8N7L6|uniprotkb:Q9BSQ9|ensembl:ENSP00000264230	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:noa1_human(display_long)|uniprotkb:NOA1(gene name)|psi-mi:NOA1(display_short)|uniprotkb:C4orf14(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_115689.1|ensembl:ENSG00000084092(gene)|ensembl:ENST00000264230(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0010941"(regulation of cell death)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043457"(regulation of cellular respiration)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:lynfPNtWZ/q7Df9/hpwiyIjUD2Y9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P36969	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2510844|uniprotkb:O43381|uniprotkb:Q9UPK2|uniprotkb:Q6PJ59|ensembl:ENSP00000346103	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gpx4_human(display_long)|uniprotkb:GPX4(gene name)|psi-mi:GPX4(display_short)|uniprotkb:Glutathione peroxidase 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002076.2|refseq:NP_001034936.1|dip:DIP-53543N|reactome:R-HSA-9023661|reactome:R-HSA-9020265|ensembl:ENSG00000167468(gene)|ensembl:ENST00000354171(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008430"(selenium binding)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051258"(protein polymerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0110076"(negative regulation of ferroptosis)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|rcsb pdb:2GS3|rcsb pdb:2OBI|rcsb pdb:5H5Q|rcsb pdb:5H5R|rcsb pdb:5H5S|rcsb pdb:6ELW|rcsb pdb:6HKQ|rcsb pdb:6HN3|reactome:R-HSA-2142688|reactome:R-HSA-2142712|reactome:R-HSA-2142770|reactome:R-HSA-9018676|reactome:R-HSA-9018896	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:SUjUUl4rV/SKmLkV6WOiM+nusio9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14656	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-524257|uniprotkb:Q53Y64|uniprotkb:Q96CA0|uniprotkb:B2RB58|ensembl:ENSP00000345719	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tor1a_human(display_long)|uniprotkb:Torsin family 1 member A(gene name synonym)|uniprotkb:Dystonia 1 protein(gene name synonym)|uniprotkb:TOR1A(gene name)|psi-mi:TOR1A(display_short)|uniprotkb:DQ2(gene name synonym)|uniprotkb:DYT1(gene name synonym)|uniprotkb:TA(gene name synonym)|uniprotkb:Torsin ATPase-1A(gene name synonym)|uniprotkb:TORA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000136827(gene)|ensembl:ENST00000351698(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006996"(organelle organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030426"(growth cone)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051584"(regulation of dopamine uptake involved in synaptic transmission)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061992"(obsolete ATP-dependent chaperone mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR010448(Torsin)|interpro:IPR017378(Torsin, subgroup)|interpro:IPR027417|interpro:IPR030549|rcsb pdb:5J1S|rcsb pdb:5J1T|rcsb pdb:6OIF|reactome:R-HSA-8856825|go:"GO:0031175"(neuron projection development)|refseq:NP_000104.1|dip:DIP-34411N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:PeqPtp4z9AnOwDH1GXYATMaihkM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TED1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11721746|ensembl:ENSP00000423822	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gpx8_human(display_long)|uniprotkb:GPX8(gene name)|psi-mi:GPX8(display_short)|uniprotkb:UNQ847/PRO1785(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000164294(gene)|ensembl:ENST00000503787(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034599"(cellular response to oxidative stress)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR013376(Glutathione peroxidase Gpx7, putative)|interpro:IPR029760|interpro:IPR036249|rcsb pdb:3CYN|rcsb pdb:3KIJ|reactome:R-HSA-3299685|refseq:NP_001008398.2|refseq:NP_001293126.1|refseq:NP_001293127.1|refseq:NP_001293130.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4Uu1pe2vaf0KS3mZyZJpSakdOvU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H4I3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3229670|ensembl:ENSP00000305664|ensembl:ENSP00000370295|ensembl:ENSP00000379171|uniprotkb:Q9H7N1|uniprotkb:Q9UGX6|uniprotkb:Q96ED8|uniprotkb:Q9UGX7|uniprotkb:Q19CC5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:trabd_human(display_long)|uniprotkb:TRABD(gene name)|psi-mi:TRABD(display_short)|uniprotkb:TTG2(gene name synonym)|uniprotkb:Protein TTG2(gene name synonym)|uniprotkb:PP2447(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000170638(gene)|ensembl:ENST00000303434(transcript)|ensembl:ENST00000380909(transcript)|ensembl:ENST00000395827(transcript)|interpro:IPR002816(Pheromone shutdown-related, TraB)|mint:Q9H4I3|refseq:NP_079480.2|refseq:NP_001307413.1|refseq:NP_001307414.1|refseq:NP_001307416.1|refseq:NP_001307417.1|refseq:XP_016884433.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9jCR5jBtTBh7MqIRiCIq2WECSlA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H9A6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043135|uniprotkb:Q9NXC1|uniprotkb:Q9BTR7|uniprotkb:Q9NSK1|ensembl:ENSP00000359990	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lrc40_human(display_long)|uniprotkb:LRRC40(gene name)|psi-mi:LRRC40(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000066557(gene)|ensembl:ENST00000370952(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|refseq:NP_060238.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DxDqTX9DvC1eU/vjACu8pZLo+Qk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UNL2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043938|uniprotkb:Q549M4|ensembl:ENSP00000265044|uniprotkb:B2R7D0|uniprotkb:D3DNK5|uniprotkb:B4E2P2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ssrg_human(display_long)|uniprotkb:Signal sequence receptor subunit gamma(gene name synonym)|uniprotkb:SSR3(gene name)|psi-mi:SSR3(display_short)|uniprotkb:TRAPG(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_009038.1|ensembl:ENSG00000114850(gene)|ensembl:ENST00000265044(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009779(Translocon-associated, gamma subunit)|mint:Q9UNL2|reactome:R-HSA-1799339|refseq:NP_001295126.1|refseq:NP_001295133.1|refseq:NP_001295134.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Fb918T41oaTpc+kzNIygp1h1tlo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q07954	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1046087|uniprotkb:Q8IVG8|uniprotkb:Q2PP12|uniprotkb:Q86SW0|ensembl:ENSP00000243077	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lrp1_human(display_long)|uniprotkb:Alpha-2-macroglobulin receptor(gene name synonym)|uniprotkb:Apolipoprotein E receptor(gene name synonym)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:A2MR(gene name synonym)|uniprotkb:APR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002323.2|ensembl:ENSG00000123384(gene)|ensembl:ENST00000243077(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002020"(protease binding)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016964"(alpha-2 macroglobulin receptor activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030226"(apolipoprotein receptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032370"(positive regulation of lipid transport)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0032429"(regulation of phospholipase A2 activity)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045177"(apical part of cell)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048694"(positive regulation of collateral sprouting of injured axon)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0061642"(chemoattraction of axon)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1904300"(positive regulation of transcytosis)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905049"(negative regulation of metallopeptidase activity)|go:"GO:1905167"(positive regulation of lysosomal protein catabolic process)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR032485|interpro:IPR036055|rcsb pdb:1CR8|rcsb pdb:1D2L|rcsb pdb:1J8E|rcsb pdb:2FYJ|rcsb pdb:2FYL|rcsb pdb:2KNX|rcsb pdb:2KNY|reactome:R-HSA-2168880|reactome:R-HSA-975634|dip:DIP-50613N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:eO2l3huuq6NYoVoYdoCloLqrlRw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q99426	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-764356|uniprotkb:O00111|uniprotkb:O00674|uniprotkb:O14728|uniprotkb:Q6FGY5|ensembl:ENSP00000221855	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tbcb_human(display_long)|uniprotkb:Tubulin-specific chaperone B(gene name synonym)|uniprotkb:Cytoskeleton-associated protein 1(gene name synonym)|uniprotkb:Cytoskeleton-associated protein CKAPI(gene name synonym)|uniprotkb:TBCB(gene name)|psi-mi:TBCB(display_short)|uniprotkb:CG22(gene name synonym)|uniprotkb:CKAP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001272.2|refseq:NP_001287900.1|dip:DIP-34409N|ensembl:ENSG00000105254(gene)|ensembl:ENST00000221855(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007399"(nervous system development)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000626(Ubiquitin)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR029071|interpro:IPR036859|reactome:R-HSA-389977|go:"GO:0030154"(cell differentiation)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:HHMamwtPQscu/rkhdarbQl6/hcw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75521	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2512024|ensembl:ENSP00000369461|uniprotkb:Q9NYH7|uniprotkb:Q9NQH1|uniprotkb:Q9H0T9|uniprotkb:Q5JYK7|uniprotkb:Q7L124|uniprotkb:Q9UN55|uniprotkb:Q9BUE9|uniprotkb:Q8N0X0|uniprotkb:Q5JYK5|intact:EBI-2802486	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:eci2_human(display_long)|uniprotkb:ECI2(gene name)|psi-mi:ECI2(display_short)|uniprotkb:DRS1(gene name synonym)|uniprotkb:HCA88(gene name synonym)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Diazepam-binding inhibitor-related protein 1(gene name synonym)|uniprotkb:DRS-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 88(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-1(gene name synonym)|uniprotkb:PECI(gene name synonym)|uniprotkb:Peroxisomal 3,2-trans-enoyl-CoA isomerase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000198721(gene)|ensembl:ENST00000380118(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR022408|interpro:IPR029045|interpro:IPR035984|mint:O75521|rcsb pdb:2CQU|rcsb pdb:2F6Q|rcsb pdb:4U18|rcsb pdb:4U19|rcsb pdb:4U1A|reactome:R-HSA-390247|reactome:R-HSA-9033241|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR001753(Crotonase, core)|refseq:NP_001159482.1|refseq:NP_006108.2|refseq:NP_996667.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:AIR8lybsBusmVmjgsN0Hcl6p+3g9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P08240	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-726981|ensembl:ENSP00000328023|uniprotkb:Q9BVJ4|uniprotkb:A6NIB3|uniprotkb:B2R5Z8|uniprotkb:B4E0H3|uniprotkb:E9PJS4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:srpra_human(display_long)|uniprotkb:SRPRA(gene name)|psi-mi:SRPRA(display_short)|uniprotkb:Docking protein alpha(gene name synonym)|uniprotkb:SRPR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	rcsb pdb:2FH5|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0016020"(membrane)|rcsb pdb:2GO5|go:"GO:0045047"(protein targeting to ER)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|rcsb pdb:5L3Q|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007222(Signal recognition particle receptor, alpha subunit, N-terminal)|interpro:IPR011012(Longin-like)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR027417|interpro:IPR036225|interpro:IPR042101|mint:P08240|rcsb pdb:6Y32|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|ensembl:ENSG00000182934(gene)|ensembl:ENST00000332118(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005785"(signal recognition particle receptor complex)|refseq:NP_001171313.1|refseq:NP_003130.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4ag/lxPfDGSDWhpnuwQynTvCpuU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8IWF2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z3U7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358882|uniprotkb:A5D8U7|uniprotkb:A7E2Y0|uniprotkb:Q86TA2|uniprotkb:Q8N3I5|uniprotkb:Q8NAI0|uniprotkb:Q9UPW1|intact:EBI-2829603|intact:EBI-358896|uniprotkb:Q8NHE2|uniprotkb:B9EGP5|uniprotkb:F8VWA6|uniprotkb:F8W1Z6|intact:EBI-10962461|ensembl:ENSP00000377250	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mon2_human(display_long)|uniprotkb:MON2(gene name)|psi-mi:MON2(display_short)|uniprotkb:KIAA1040(gene name synonym)|uniprotkb:SF21(gene name synonym)|uniprotkb:Protein SF21(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001265399.1|refseq:NP_001265398.1|refseq:NP_055841.2|refseq:XP_016874530.1|ensembl:ENSG00000061987(gene)|ensembl:ENST00000393630(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026829|interpro:IPR032629|interpro:IPR032691|interpro:IPR032817|mint:Q7Z3U7	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:pEkENsLrswc7Cb2WTKZfQdESrtQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14734	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1237371|uniprotkb:O15261|uniprotkb:Q17RX4|ensembl:ENSP00000217455	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acot8_human(display_long)|uniprotkb:ACOT8(gene name)|psi-mi:ACOT8(display_short)|uniprotkb:ACTEIII(gene name synonym)|uniprotkb:PTE1(gene name synonym)|uniprotkb:Choloyl-coenzyme A thioesterase(gene name synonym)|uniprotkb:Peroxisomal acyl-coenzyme A thioester hydrolase 1(gene name synonym)|uniprotkb:Peroxisomal long-chain acyl-CoA thioesterase 1(gene name synonym)|uniprotkb:HIV-Nef-associated acyl-CoA thioesterase(gene name synonym)|uniprotkb:Thioesterase II(gene name synonym)|uniprotkb:Peroxisomal acyl-CoA thioesterase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005460.2|dip:DIP-38179N|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043649"(dicarboxylic acid catabolic process)|go:"GO:0044466"(glutaryl-CoA hydrolase activity)|go:"GO:0045225"(negative regulation of CD4 production)|go:"GO:0047603"(acetoacetyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0047994"(hydroxymethylglutaryl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0052815"(medium-chain acyl-CoA hydrolase activity)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|interpro:IPR003703(Acyl-CoA thioesterase)|interpro:IPR029069|interpro:IPR042171|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|ensembl:ENSG00000101473(gene)|ensembl:ENST00000217455(transcript)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0004778"(succinyl-CoA hydrolase activity)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016289"(CoA hydrolase activity)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016559"(peroxisome fission)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0033882"(choloyl-CoA hydrolase activity)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Q8Y3l4ysgKPMi3mJU2/g8mVxWE09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TC12	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2823756|uniprotkb:Q0QD40|uniprotkb:B4DDW0|uniprotkb:A8K062|uniprotkb:B2RB26|uniprotkb:A6NDK3|uniprotkb:Q6IAH5|uniprotkb:Q9NRW0|uniprotkb:Q9Y391|ensembl:ENSP00000370750	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rdh11_human(display_long)|uniprotkb:RDH11(gene name)|psi-mi:RDH11(display_short)|uniprotkb:ARSDR1(gene name synonym)|uniprotkb:PSDR1(gene name synonym)|uniprotkb:Androgen-regulated short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:HCV core-binding protein HCBP12(gene name synonym)|uniprotkb:Prostate short-chain dehydrogenase/reductase 1(gene name synonym)|uniprotkb:Retinal reductase 1(gene name synonym)|uniprotkb:SDR7C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 7C member 1(gene name synonym)|uniprotkb:CGI-82(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0110095"(cellular detoxification of aldehyde)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q8TC12|reactome:R-HSA-2453902|reactome:R-HSA-5365859|reactome:R-HSA-975634|refseq:NP_057110.3|refseq:NP_001239579.1|ensembl:ENSG00000072042(gene)|ensembl:ENST00000381346(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0004745"(NAD-retinol dehydrogenase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0102354"(11-cis-retinol dehydrogenase activity)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:elUutgO+T5gnwthTzc4WDetnuug9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15738	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4280135|uniprotkb:D3DWT6|uniprotkb:O00344|ensembl:ENSP00000359297|ensembl:ENSP00000391854	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nsdhl_human(display_long)|uniprotkb:NSDHL(gene name)|psi-mi:NSDHL(display_short)|uniprotkb:H105E3(gene name synonym)|uniprotkb:Protein H105e3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011529480.1|refseq:NP_001123237.1|refseq:NP_057006.1|ensembl:ENSG00000147383(gene)|ensembl:ENST00000370274(transcript)|ensembl:ENST00000440023(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0003854"(3-beta-hydroxy-delta5-steroid dehydrogenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0047012"("sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity")|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0102175"(3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity)|go:"GO:0103066"("4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity")|go:"GO:0103067"("4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity")|interpro:IPR002225(3-beta hydroxysteroid dehydrogenase/isomerase)|interpro:IPR036291|mint:Q15738|rcsb pdb:6JKG|rcsb pdb:6JKH|reactome:R-HSA-191273|go:"GO:0000252"("C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity")	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Hfd2Gvro+f9sk/Wn2Dxsgh1nbfo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:B2RPK0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943428	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hgb1a_human(display_long)|uniprotkb:HMGB1P1(gene name)|psi-mi:HMGB1P1(display_short)|uniprotkb:HMG1L1(gene name synonym)|uniprotkb:HMGB1L1(gene name synonym)|uniprotkb:High mobility group protein B1 pseudogene 1(gene name synonym)|uniprotkb:Putative high mobility group protein 1-like 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|mint:B2RPK0|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR031076|interpro:IPR036910	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ppgkTWseGeSKMW8zLWwg1AmkhlY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q2NKX8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1042535|uniprotkb:Q8NCI1|uniprotkb:Q96H93|uniprotkb:Q9NXQ8|intact:EBI-2560904|ensembl:ENSP00000334675	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:erc6l_human(display_long)|uniprotkb:ERCC6L(gene name)|psi-mi:ERCC6L(display_short)|uniprotkb:PICH(gene name synonym)|uniprotkb:ATP-dependent helicase ERCC6-like(gene name synonym)|uniprotkb:PLK1-interacting checkpoint helicase(gene name synonym)|uniprotkb:Tumor antigen BJ-HCC-15(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060139.2|ensembl:ENSG00000186871(gene)|ensembl:ENST00000334463(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR038718|rcsb pdb:5JNO|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3HZtZq9pgDyQB+UcxtAQjHv7+7o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P11274	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-712838|intact:EBI-28971369|ensembl:ENSP00000303507|uniprotkb:P78501|uniprotkb:Q12842|uniprotkb:Q4LE80|uniprotkb:Q6NZI3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:bcr_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-26(gene name synonym)|uniprotkb:BCR(gene name)|psi-mi:BCR(display_short)|uniprotkb:BCR1(gene name synonym)|uniprotkb:D22S11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000186716(gene)|ensembl:ENST00000305877(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR015123(Bcr-Abl oncoprotein oligomerisation)|interpro:IPR035892|interpro:IPR035899|interpro:IPR036481|interpro:IPR037769|rcsb pdb:1K1F|rcsb pdb:2AIN|rcsb pdb:5N6R|rcsb pdb:5N7E|rcsb pdb:5OC7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|mint:P11274|ensembl:ENSP00000303507|ensembl:ENST00000359540|ensembl:ENSP00000352535|refseq:NP_004318.3|refseq:NP_067585.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:U2+lPQ5c2dVW2MPLvknA0Bbg4fA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P46734	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-602462|uniprotkb:Q99441|uniprotkb:Q9UE71|uniprotkb:Q9UE72|uniprotkb:B3KSK7|ensembl:ENSP00000345083	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mp2k3_human(display_long)|uniprotkb:MAPK/ERK kinase 3(gene name synonym)|uniprotkb:MAP2K3(gene name)|psi-mi:MAP2K3(display_short)|uniprotkb:MEK3(gene name synonym)|uniprotkb:MKK3(gene name synonym)|uniprotkb:PRKMK3(gene name synonym)|uniprotkb:SKK2(gene name synonym)|uniprotkb:Stress-activated protein kinase kinase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002747.2|refseq:NP_659731.1|refseq:XP_011522261.1|refseq:XP_016880347.1|refseq:XP_016880348.1|refseq:NP_001303261.1|refseq:XP_005256780.1|dip:DIP-34242N|ensembl:ENSG00000034152(gene)|ensembl:ENST00000342679(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0090398"(cellular senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P46734|reactome:R-HSA-2559580|reactome:R-HSA-450302|reactome:R-HSA-5210891	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:OcAgoYfpPPQycfZ6tr52FCRzcOU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BRX2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043580|uniprotkb:Q9GZS6|uniprotkb:Q9Y306|ensembl:ENSP00000274311	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pelo_human(display_long)|uniprotkb:PELO(gene name)|psi-mi:PELO(display_short)|uniprotkb:CGI-17(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000152684(gene)|ensembl:ENST00000274311(transcript)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007049"(cell cycle)|go:"GO:0007492"(endoderm development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|mint:Q9BRX2|rcsb pdb:1X52|rcsb pdb:5EO3|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|refseq:NP_057030.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:EZIi8JN2tu0u4oH06fOus3LKjoo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P07741	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1047565|uniprotkb:Q3KP55|uniprotkb:G5E9J2|uniprotkb:Q68DF9|ensembl:ENSP00000367615	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:apt_human(display_long)|uniprotkb:APRT(gene name)|psi-mi:APRT(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000476.1|ensembl:ENSG00000198931(gene)|ensembl:ENST00000378364(transcript)|go:"GO:0002055"(adenine binding)|go:"GO:0003999"(adenine phosphoribosyltransferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0007595"(lactation)|go:"GO:0007625"(grooming behavior)|go:"GO:0016208"(AMP binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0044209"(AMP salvage)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005764(Adenine phosphoribosyl transferase)|interpro:IPR029057|rcsb pdb:1OPU|rcsb pdb:1ORE|rcsb pdb:1ZN7|rcsb pdb:1ZN8|rcsb pdb:1ZN9|rcsb pdb:4X44|rcsb pdb:4X45|rcsb pdb:6FCH|rcsb pdb:6FCI|rcsb pdb:6FCL|rcsb pdb:6FD4|rcsb pdb:6FD5|rcsb pdb:6FD6|rcsb pdb:6HGP|rcsb pdb:6HGQ|rcsb pdb:6HGR|rcsb pdb:6HGS|reactome:R-HSA-6798695|reactome:R-HSA-74217|refseq:NP_001025189.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:x046RPUzHysaN5PWMM0UCSyt9xI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BRR6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-723761|uniprotkb:Q49AU7|uniprotkb:Q8NBI1|uniprotkb:Q8WZ90|uniprotkb:Q96NF8|uniprotkb:Q9H0A7|ensembl:ENSP00000397694	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:adpgk_human(display_long)|uniprotkb:RbBP-35(gene name synonym)|uniprotkb:ADPGK(gene name)|psi-mi:ADPGK(display_short)|uniprotkb:PSEC0260(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_112574.3|refseq:XP_006720775.1|ensembl:ENSG00000159322(gene)|ensembl:ENST00000456471(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0043843"(ADP-specific glucokinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0061620"(glycolytic process through glucose-6-phosphate)|interpro:IPR007666(ADP-specific phosphofructokinase/glucokinase)|mint:Q9BRR6|reactome:R-HSA-70171|interpro:IPR029056	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:jeRKymflPO3JABiI6J42cZZEbwc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NX40	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2683029|uniprotkb:C9K030|uniprotkb:Q9BZE8|ensembl:ENSP00000264312|ensembl:ENSP00000370882|ensembl:ENSP00000423002|ensembl:ENSP00000423909|uniprotkb:G8JLN7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ocad1_human(display_long)|uniprotkb:OCIA(gene name synonym)|uniprotkb:Ovarian carcinoma immunoreactive antigen(gene name synonym)|uniprotkb:OCIAD1(gene name)|psi-mi:OCIAD1(display_short)|uniprotkb:ASRIJ(gene name synonym)|uniprotkb:Ovarian cancer immunoreactive antigen domain containing 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001073309.1|refseq:NP_001073311.2|refseq:NP_001073308.1|refseq:NP_001073310.1|refseq:NP_060300.1|ensembl:ENSG00000109180(gene)|ensembl:ENST00000264312(transcript)|ensembl:ENST00000381473(transcript)|ensembl:ENST00000508293(transcript)|ensembl:ENST00000513391(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187|mint:Q9NX40|refseq:XP_016863818.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:e3Ojv8LBlgj056bssUZjEC+MB+Q9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14735	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358858|uniprotkb:Q6FGU1|uniprotkb:Q6ZN70|ensembl:ENSP00000219789|ensembl:ENSP00000454453|ensembl:ENSP00000457339|uniprotkb:B4DUV0|uniprotkb:H3BTV1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cdipt_human(display_long)|uniprotkb:CDIPT(gene name)|psi-mi:CDIPT(display_short)|uniprotkb:PIS(gene name synonym)|uniprotkb:PIS1(gene name synonym)|uniprotkb:Phosphatidylinositol synthase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001273514.1|refseq:NP_006310.1|ensembl:ENSG00000103502(gene)|ensembl:ENST00000219789(transcript)|ensembl:ENST00000569956(transcript)|ensembl:ENST00000570016(transcript)|go:"GO:0003881"(CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043178"(alcohol binding)|go:"GO:0046341"(CDP-diacylglycerol metabolic process)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014387(CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote)|interpro:IPR043130|reactome:R-HSA-1483226|dip:DIP-54492N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:SIs1nKd3UxZREA2Sxl4MxxBNYvM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UK99	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2509901|uniprotkb:B3KY16|uniprotkb:D3DR05|uniprotkb:Q9H0V2|uniprotkb:Q86X90|uniprotkb:Q9NUX2|ensembl:ENSP00000265651	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:fbx3_human(display_long)|uniprotkb:FBXO3(gene name)|psi-mi:FBXO3(display_short)|uniprotkb:FBX3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_036307.2|refseq:NP_208385.1|dip:DIP-53688N|ensembl:ENSG00000110429(gene)|ensembl:ENST00000265651(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007474(ApaG)|interpro:IPR018958|interpro:IPR028388|interpro:IPR036047|interpro:IPR036767|interpro:IPR037883|rcsb pdb:5HDW	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:zQB8ig3s51tXN81NtMrou84Rv6I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NE01	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-741032|ensembl:ENSP00000305449|uniprotkb:Q8TBV4|uniprotkb:Q96IW4|uniprotkb:Q9NRK4|uniprotkb:Q9NXW6|uniprotkb:B3KX67	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cnnm3_human(display_long)|uniprotkb:Cyclin-M3(gene name synonym)|uniprotkb:Ancient conserved domain-containing protein 3(gene name synonym)|uniprotkb:CNNM3(gene name)|psi-mi:CNNM3(display_short)|uniprotkb:ACDP3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060093.3|refseq:NP_951060.1|ensembl:ENSG00000168763(gene)|ensembl:ENST00000305510(transcript)|go:"GO:0006811"(ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR044751|mint:Q8NE01|rcsb pdb:5K22|rcsb pdb:5K23|rcsb pdb:5K25|rcsb pdb:5TSR|rcsb pdb:6DFD|rcsb pdb:6MN6|rcsb pdb:6WUR|go:"GO:0005886"(plasma membrane)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:AHuatMC/j3lteiKZli8vu5ZM6vk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P46020	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3506881|uniprotkb:B7ZL05|uniprotkb:Q2M3D7|uniprotkb:B7ZL07|ensembl:ENSP00000362643	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kpb1_human(display_long)|uniprotkb:PHKA1(gene name)|psi-mi:PHKA1(display_short)|uniprotkb:PHKA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001116142.1|refseq:NP_002628.2|refseq:NP_001165907.1|ensembl:ENSG00000067177(gene)|ensembl:ENST00000373542(transcript)|go:"GO:0004689"(phosphorylase kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005964"(phosphorylase kinase complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006091"(generation of precursor metabolites and energy)|interpro:IPR008734(Phosphorylase kinase alphabeta)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR011613(Glycoside hydrolase 15-related)|interpro:IPR012341(Six-hairpin glycosidase)|reactome:R-HSA-70221	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:1/ojdajR7F5sfEKBHNMekVXTGzw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q04323	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1058647|ensembl:ENSP00000303991|uniprotkb:Q9BV93|uniprotkb:Q9BVV5|intact:EBI-1993649	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ubxn1_human(display_long)|uniprotkb:UBXN1(gene name)|psi-mi:UBXN1(display_short)|uniprotkb:SAKS1(gene name synonym)|uniprotkb:SAPK substrate protein 1(gene name synonym)|uniprotkb:UBA/UBX 33.3 kDa protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000162191(gene)|ensembl:ENST00000301935(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|refseq:NP_001273006.1|refseq:NP_001273007.1|refseq:NP_056937.2|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051117"(ATPase binding)|go:"GO:0071796"(K6-linked polyubiquitin modification-dependent protein binding)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1904293"(negative regulation of ERAD pathway)|go:"GO:1904855"(proteasome regulatory particle binding)|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR041923|reactome:R-HSA-532668|reactome:R-HSA-5693565|go:"GO:0043130"(ubiquitin binding)|refseq:XP_005274090.1|refseq:XP_016873363.1|dip:DIP-29467N	go:"GO:0043229"(intracellular organelle)	-	crc64:E4E0C8BBAC93F2BB	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:KdHMRM9FSd6VT6MvJTxzdjARlRw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6P4Q7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11918149|ensembl:ENSP00000366275|uniprotkb:B7Z1U0|uniprotkb:C7SQM3|uniprotkb:C7SQM4|uniprotkb:C7SQM5|uniprotkb:Q53RE5|uniprotkb:Q9H9G3|uniprotkb:Q9HCI0|uniprotkb:Q9NRN1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cnnm4_human(display_long)|uniprotkb:CNNM4(gene name)|psi-mi:CNNM4(display_short)|uniprotkb:ACDP4(gene name synonym)|uniprotkb:Ancient conserved domain-containing protein 4(gene name synonym)|uniprotkb:Cyclin-M4(gene name synonym)|uniprotkb:KIAA1592(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000158158(gene)|ensembl:ENST00000377075(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007601"(visual perception)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0015081"(sodium ion transmembrane transporter activity)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050896"(response to stimulus)|go:"GO:0055065"(metal ion homeostasis)|go:"GO:0070166"(enamel mineralization)|interpro:IPR000595(Cyclic nucleotide-binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030425"(dendrite)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR002550(Protein of unknown function DUF21)|interpro:IPR018490|interpro:IPR044751|rcsb pdb:6G52|rcsb pdb:6RS2|refseq:NP_064569.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:sdYQzd8X3Gz9Okurljb9g+Homt89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NBQ5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1052304|uniprotkb:Q96HF6|uniprotkb:Q9UKU4|ensembl:ENSP00000351035	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dhb11_human(display_long)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 11(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase XI(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 8(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase 2(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen HD-CL-03(gene name synonym)|uniprotkb:HSD17B11(gene name)|psi-mi:HSD17B11(display_short)|uniprotkb:DHRS8(gene name synonym)|uniprotkb:PAN1B(gene name synonym)|uniprotkb:SDR16C2(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 16C member 2(gene name synonym)|uniprotkb:PSEC0029(orf name)|uniprotkb:UNQ207/PRO233(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057329.3|ensembl:ENSG00000198189(gene)|ensembl:ENST00000358290(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0006710"(androgen catabolic process)|go:"GO:0016229"(steroid dehydrogenase activity)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q8NBQ5|rcsb pdb:1YB1|reactome:R-HSA-193144	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:jWhP4Y15W31yQ1WiYLQ5NRK6bYw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H5K3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11337900|ensembl:ENSP00000331258|ensembl:ENSP00000502774	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sg196_human(display_long)|uniprotkb:POMK(gene name)|psi-mi:POMK(display_short)|uniprotkb:Protein kinase-like protein SgK196(gene name synonym)|uniprotkb:SGK196(gene name synonym)|uniprotkb:Sugen kinase 196(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001264900.1|refseq:NP_115613.1|ensembl:ENSG00000185900(gene)|ensembl:ENST00000331373(transcript)|ensembl:ENST00000676193(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0007420"(brain development)|go:"GO:0007611"(learning or memory)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|go:"GO:0019200"(carbohydrate kinase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0050905"(neuromuscular process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR039318|reactome:R-HSA-5173105	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ALGaeqMBE/xzmOL9wBqzCZGBGn49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13188	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:slrC4Ax6263chBC1DJygdoExuCc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15006	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N2K0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6269657|uniprotkb:A6NED4|uniprotkb:A6NJ90|uniprotkb:A8K450|uniprotkb:B4DE71|uniprotkb:Q5T710|uniprotkb:Q5T711|uniprotkb:Q96CR1|uniprotkb:Q9BX05|uniprotkb:Q9NPX7|uniprotkb:Q9UFV6|ensembl:ENSP00000341408	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:abd12_human(display_long)|uniprotkb:ABHD12(gene name)|psi-mi:ABHD12(display_short)|uniprotkb:C20orf22(gene name synonym)|uniprotkb:Abhydrolase domain-containing protein 12(gene name synonym)|uniprotkb:2-arachidonoylglycerol hydrolase ABHD12(gene name synonym)|uniprotkb:Monoacylglycerol lipase ABHD12(gene name synonym)|uniprotkb:Oxidized phosphatidylserine lipase ABHD12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001035937.1|refseq:NP_056415.1|ensembl:ENSP00000341408|ensembl:ENST00000376542|ensembl:ENSP00000365725|ensembl:ENSG00000100997(gene)|ensembl:ENST00000339157(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006660"(phosphatidylserine catabolic process)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0046464"(acylglycerol catabolic process)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0052651"(monoacylglycerol catabolic process)|interpro:IPR022742|interpro:IPR026605|interpro:IPR029058|mint:Q8N2K0|reactome:R-HSA-426048	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:l5KeOxi83Cng20JUGy7ybEtoCPg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9C0E2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1044855|uniprotkb:Q5VUZ5|uniprotkb:Q9H934|uniprotkb:Q8N3V6|ensembl:ENSP00000255305	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:xpo4_human(display_long)|uniprotkb:XPO4(gene name)|psi-mi:XPO4(display_short)|uniprotkb:KIAA1721(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_071904.4|ensembl:ENSG00000132953(gene)|ensembl:ENST00000255305(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0046827"(positive regulation of protein export from nucleus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR044189|mint:Q9C0E2|go:"GO:0005643"(nuclear pore)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+7lQFg9CBnDLFt9rqjLb//HPJnQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15091	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2107070|ensembl:ENSP00000440915|uniprotkb:D3DS99|uniprotkb:D3DSA1|uniprotkb:B4DXD9|uniprotkb:B4E0S8|uniprotkb:B4E211|uniprotkb:Q86SZ4|uniprotkb:Q86YB5|uniprotkb:Q8N5L5|uniprotkb:C4AM93	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mrpp3_human(display_long)|uniprotkb:PRORP(gene name)|psi-mi:PRORP(display_short)|uniprotkb:KIAA0391(gene name synonym)|uniprotkb:MRPP3(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 3(gene name synonym)|uniprotkb:Protein only RNase P catalytic subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000100890(gene)|ensembl:ENST00000534898(transcript)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR031595|interpro:IPR033495|mint:O15091|refseq:XP_011535711.1|refseq:XP_011535712.1|refseq:NP_055487.2|refseq:NP_001243607.1|refseq:NP_001243608.1|refseq:NP_001243609.1|refseq:NP_001243610.1|refseq:XP_005268294.1|refseq:XP_016877324.1|refseq:XP_016877325.1|refseq:XP_016877326.1|rcsb pdb:4ROU|rcsb pdb:4XGL|rcsb pdb:4XGM|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-8868766	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ecyf1CIBRAhf7Fgt7+UfnVcNHfs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8WUY1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1170414|uniprotkb:Q8NBN2|uniprotkb:Q9NYI2|uniprotkb:B2RDN6|intact:EBI-2563242|ensembl:ENSP00000338607	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:them6_human(display_long)|uniprotkb:THEM6(gene name)|psi-mi:THEM6(display_short)|uniprotkb:C8orf55(gene name synonym)|uniprotkb:Mesenchymal stem cell protein DSCD75(gene name synonym)|uniprotkb:Thioesterase superfamily member 6(gene name synonym)|uniprotkb:PSEC0098(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057731.1|ensembl:ENSG00000130193(gene)|ensembl:ENST00000336138(transcript)|go:"GO:0005576"(extracellular region)|interpro:IPR029069	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VCZRUm2WiwLdWnKB8jTuOvLy+4A9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8WY22	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-359348|uniprotkb:Q8WY23|ensembl:ENSP00000340761|ensembl:ENSP00000500359	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:bri3b_human(display_long)|uniprotkb:BRI3BP(gene name)|psi-mi:BRI3BP(display_short)|uniprotkb:KG19(gene name synonym)|uniprotkb:Cervical cancer 1 proto-oncogene-binding protein KG19(gene name synonym)|uniprotkb:HCCRBP-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_542193.3|ensembl:ENSG00000184992(gene)|ensembl:ENST00000341446(transcript)|ensembl:ENST00000672415(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR033367	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:O9epHcfM1m7xNvrm6ELo0fRRGV49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96JQ2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5658691|uniprotkb:Q9H713|uniprotkb:Q9UFP4|uniprotkb:Q9HA57|uniprotkb:Q9ULN2|uniprotkb:Q9HA23|uniprotkb:B2RAR7|intact:EBI-28974156|ensembl:ENSP00000298912	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:clmn_human(display_long)|uniprotkb:Calponin-like transmembrane domain protein(gene name synonym)|uniprotkb:KIAA1188(gene name synonym)|uniprotkb:CLMN(gene name)|psi-mi:CLMN(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000298912|refseq:NP_079010.2|ensembl:ENSG00000165959(gene)|ensembl:ENST00000298912(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007097"(nuclear migration)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0051015"(actin filament binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5680uLyZVmMQ3D5tHa3nBD2b+Hg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NBM4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y2L1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-373539|uniprotkb:A6NI21|uniprotkb:Q5W0P7|uniprotkb:Q5W0P8|uniprotkb:Q658Z7|uniprotkb:Q7Z481|uniprotkb:Q8WWI2|uniprotkb:Q9UG36|uniprotkb:B2RBL2|ensembl:ENSP00000366997	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rrp44_human(display_long)|uniprotkb:DIS3(gene name)|psi-mi:DIS3(display_short)|uniprotkb:Ribosomal RNA-processing protein 44(gene name synonym)|uniprotkb:Protein DIS3 homolog(gene name synonym)|uniprotkb:KIAA1008(gene name synonym)|uniprotkb:RRP44(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001121698.1|refseq:NP_055768.3|ensembl:ENSG00000083520(gene)|ensembl:ENST00000377767(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR029060|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q9Y2L1|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:cHOcZh1JkvywNK4Tq2DUvPMm6kc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H7B2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1051960|uniprotkb:Q8N4A1|uniprotkb:Q5VXN1|ensembl:ENSP00000402338	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rpf2_human(display_long)|uniprotkb:RPF2(gene name)|psi-mi:RPF2(display_short)|uniprotkb:BXDC1(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF2 homolog(gene name synonym)|uniprotkb:Brix domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_115570.1|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007109(Brix)|interpro:IPR039770|mint:Q9H7B2|ensembl:ENSG00000197498(gene)|ensembl:ENST00000441448(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:CXU4CHQmcrISLS8GDIwEMGhiaQI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O94887	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2806886|uniprotkb:Q53QM5|uniprotkb:Q9UFE7|uniprotkb:Q8WU27|ensembl:ENSP00000264042|uniprotkb:B7Z6J8|uniprotkb:F5GZ84	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:farp2_human(display_long)|uniprotkb:KIAA0793(gene name synonym)|uniprotkb:FARP2(gene name)|psi-mi:FARP2(display_short)|uniprotkb:PLEKHC3(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 3(gene name synonym)|uniprotkb:FERM domain-including RhoGEF(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001269912.1|refseq:NP_001269913.1|refseq:NP_055623.1|ensembl:ENSG00000006607(gene)|ensembl:ENST00000264042(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007155"(cell adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0022405"(hair cycle process)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0033623"(regulation of integrin activation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071800"(podosome assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|reactome:R-HSA-399955|reactome:R-HSA-9013149	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:n/4XGmfZHwKJ3HjkCCAejaF4yfg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q02750	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-492564|ensembl:ENSP00000302486	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mp2k1_human(display_long)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)|uniprotkb:MAP2K1(gene name)|psi-mi:MAP2K1(display_short)|uniprotkb:MEK1(gene name synonym)|uniprotkb:PRKMK1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002746.1|refseq:XP_016877900.1|dip:DIP-201N|ensembl:ENSG00000169032(gene)|ensembl:ENST00000307102(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030878"(thyroid gland development)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048538"(thymus development)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q02750|rcsb pdb:1S9J|rcsb pdb:2P55|rcsb pdb:3DV3|rcsb pdb:3DY7|rcsb pdb:3E8N|rcsb pdb:3EQB|rcsb pdb:3EQC|rcsb pdb:3EQD|rcsb pdb:3EQF|rcsb pdb:3EQG|rcsb pdb:3EQH|rcsb pdb:3EQI|rcsb pdb:3MBL|rcsb pdb:3ORN|rcsb pdb:3OS3|rcsb pdb:3PP1|rcsb pdb:3SLS|rcsb pdb:3V01|rcsb pdb:3V04|rcsb pdb:3VVH|rcsb pdb:3W8Q|rcsb pdb:3WIG|rcsb pdb:3ZLS|rcsb pdb:3ZLW|rcsb pdb:3ZLX|rcsb pdb:3ZLY|rcsb pdb:3ZM4|rcsb pdb:4AN2|rcsb pdb:4AN3|rcsb pdb:4AN9|rcsb pdb:4ANB|rcsb pdb:4ARK|rcsb pdb:4LMN|rcsb pdb:4MNE|rcsb pdb:4U7Z|rcsb pdb:4U80|rcsb pdb:4U81|rcsb pdb:5EYM|rcsb pdb:5HZE|rcsb pdb:5YT3|rcsb pdb:6NYB|rcsb pdb:6PP9|rcsb pdb:6Q0J|rcsb pdb:6Q0T|rcsb pdb:6U2G|rcsb pdb:6V2W|rcsb pdb:6X2P|rcsb pdb:6X2S|rcsb pdb:6X2X|rcsb pdb:7B3M|rcsb pdb:7B7R|rcsb pdb:7B94|rcsb pdb:7B9L|rcsb pdb:7M0T|rcsb pdb:7M0U|rcsb pdb:7M0V|rcsb pdb:7M0W|rcsb pdb:7M0X|rcsb pdb:7M0Y|rcsb pdb:7M0Z|reactome:R-HSA-110056|reactome:R-HSA-170968|reactome:R-HSA-445144|reactome:R-HSA-5210891|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5684264|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9656223|rcsb pdb:5BX0	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ieBLcDINn9hZFZZEIQ3Ktdf2NF89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NYQ6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-718852|uniprotkb:Q9BWQ5|uniprotkb:Q9Y506|uniprotkb:Q9Y526|uniprotkb:O95722|uniprotkb:Q5TH47|ensembl:ENSP00000262738	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:celr1_human(display_long)|uniprotkb:Flamingo homolog 2(gene name synonym)|uniprotkb:CELSR1(gene name)|psi-mi:CELSR1(display_short)|uniprotkb:CDHF9(gene name synonym)|uniprotkb:FMI2(gene name synonym)|uniprotkb:Cadherin family member 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055061.1|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0045176"(apical protein localization)|go:"GO:0048105"(establishment of body hair planar orientation)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060488"(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060489"(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis)|go:"GO:0060490"(lateral sprouting involved in lung morphogenesis)|go:"GO:0090251"(protein localization involved in establishment of planar polarity)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000203(GPS)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001791(Laminin G)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002126(Cadherin)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR017981|interpro:IPR020894|interpro:IPR032471|interpro:IPR036445|ensembl:ENSG00000075275(gene)|ensembl:ENST00000262738(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001764"(neuron migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:X2XbcMoTf3H1SeO8g14DwFZuWI09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HA64	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2512721|ensembl:ENSP00000269373|uniprotkb:Q969F4|uniprotkb:Q9H0U7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kt3k_human(display_long)|uniprotkb:FN3KRP(gene name)|psi-mi:FN3KRP(display_short)|uniprotkb:Fructosamine-3-kinase-related protein(gene name synonym)|uniprotkb:Protein-psicosamine 3-kinase FN3KRP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000141560(gene)|ensembl:ENST00000269373(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0016301"(kinase activity)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0102193"(protein-ribulosamine 3-kinase activity)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016477(Ketosamine-3-kinase)|reactome:R-HSA-163841|refseq:NP_078895.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DbnUHyAgUcfytGqoYbFLv4Bwg7U9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75494	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-353655|uniprotkb:Q5JRI3|uniprotkb:Q5JRI4|uniprotkb:A6NFM6|uniprotkb:A6NI42|uniprotkb:A6NIU7|uniprotkb:Q5JRH9|uniprotkb:Q5JRI2|uniprotkb:O60572|uniprotkb:Q96G09|uniprotkb:Q96P17|uniprotkb:Q5JRI0|intact:EBI-11103259|ensembl:ENSP00000420195|uniprotkb:B4DJP9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:srs10_human(display_long)|uniprotkb:FUSIP1(gene name synonym)|uniprotkb:TASR(gene name synonym)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:FUSIP2(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym)|uniprotkb:40 kDa SR-repressor protein(gene name synonym)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short)|uniprotkb:Splicing factor SRp38(gene name synonym)|uniprotkb:SFRS13A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001177936.1|refseq:NP_001177934.1|refseq:NP_001177935.1|refseq:NP_006616.1|refseq:NP_473357.1|ensembl:ENSG00000188529(gene)|ensembl:ENST00000492112(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:O75494|reactome:R-HSA-72163|refseq:NP_001177938.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:abrRZLYWl3wlG2rHzVZMgej5EWk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P52789	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-741469|uniprotkb:Q8WU87|uniprotkb:Q9UN82|ensembl:ENSP00000290573|uniprotkb:D6W5J2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hxk2_human(display_long)|uniprotkb:Hexokinase type II(gene name synonym)|uniprotkb:Muscle form hexokinase(gene name synonym)|uniprotkb:HK2(gene name)|psi-mi:HK2(display_short)|uniprotkb:Hexokinase-B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019158"(mannokinase activity)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:P52789|rcsb pdb:2NZT|rcsb pdb:5HEX|rcsb pdb:5HFU|rcsb pdb:5HG1|reactome:R-HSA-70171|go:"GO:0008865"(fructokinase activity)|ensembl:ENSG00000159399(gene)|ensembl:ENST00000290573(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007595"(lactation)|go:"GO:0008637"(apoptotic mitochondrial changes)|refseq:NP_000180.2|dip:DIP-50110N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:99w5KbKmsqMoorQz/wot6z6t2WM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y6E2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1051021|uniprotkb:Q3B779|uniprotkb:Q9H3F7|uniprotkb:A4D123|uniprotkb:Q96JW5|ensembl:ENSP00000258761|ensembl:ENSP00000397249	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:bzw2_human(display_long)|uniprotkb:BZW2(gene name)|psi-mi:BZW2(display_short)|uniprotkb:HSPC028(orf name)|uniprotkb:MSTP017(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001153239.1|refseq:NP_054757.1|ensembl:ENSG00000136261(gene)|ensembl:ENST00000258761(transcript)|ensembl:ENST00000433922(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|refseq:XP_006715769.1|refseq:XP_006715770.1|refseq:XP_006715771.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+z22Ykb6e3IM9zk51m6tjuhiEcU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O94813	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1236865|uniprotkb:O95710|uniprotkb:Q17RU3|uniprotkb:Q9Y5Q7|uniprotkb:B7ZLR5|uniprotkb:A0A0A6YYB8|ensembl:ENSP00000422591	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:slit2_human(display_long)|uniprotkb:SLIT2(gene name)|psi-mi:SLIT2(display_short)|uniprotkb:SLIL3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001276064.1|refseq:NP_001276065.1|refseq:NP_004778.1|dip:DIP-38198N|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021972"(corticospinal neuron axon guidance through spinal cord)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0050929"(induction of negative chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051414"(response to cortisol)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071676"(negative regulation of mononuclear cell migration)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|go:"GO:0090027"(negative regulation of monocyte chemotaxis)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|mint:O94813|rcsb pdb:2V70|rcsb pdb:2V9S|rcsb pdb:2V9T|rcsb pdb:2WFH|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-9010553|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|ensembl:ENSG00000145147(gene)|ensembl:ENST00000504154(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002689"(negative regulation of leukocyte chemotaxis)|go:"GO:0003180"(aortic valve morphogenesis)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:25Wc98dEfv1yROTD5pUtyQ+LWN89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NCE2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5658424|uniprotkb:Q86VK9|uniprotkb:Q6PIZ4|uniprotkb:Q8IYK1|uniprotkb:Q0JU83|uniprotkb:Q9H6C0|uniprotkb:Q6QE21|uniprotkb:Q0JTH5|uniprotkb:Q8TCM7|ensembl:ENSP00000296003	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mtmre_human(display_long)|uniprotkb:C3orf29(gene name synonym)|uniprotkb:HCV NS5A-transactivated protein 4 splice variant A-binding protein 1(gene name synonym)|uniprotkb:hJumpy(gene name synonym)|uniprotkb:MTMR14(gene name)|psi-mi:MTMR14(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001070993.1|refseq:NP_001070994.1|refseq:NP_071930.2|ensembl:ENSG00000163719(gene)|ensembl:ENST00000296003(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0016236"(macroautophagy)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR039802|interpro:IPR039803|mint:Q8NCE2|reactome:R-HSA-1632852|reactome:R-HSA-1660499	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ftagAuEsNaEzJHotTrA3OjWPPN09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BT25	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15067	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3048535|ensembl:ENSP00000301608|uniprotkb:Q15101|uniprotkb:Q16131|uniprotkb:Q9UD31|uniprotkb:Q12863|uniprotkb:Q15068|uniprotkb:Q7Z3W5|uniprotkb:A8K6X8|uniprotkb:A8KAA0|uniprotkb:B4DK61|uniprotkb:F5GYQ8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acox1_human(display_long)|uniprotkb:ACOX1(gene name)|psi-mi:ACOX1(display_short)|uniprotkb:ACOX(gene name synonym)|uniprotkb:Palmitoyl-CoA oxidase(gene name synonym)|uniprotkb:Straight-chain acyl-CoA oxidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000161533(gene)|ensembl:ENST00000301608(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0003997"(acyl-CoA oxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016401"(palmitoyl-CoA oxidase activity)|go:"GO:0016559"(peroxisome fission)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071949"(FAD binding)|go:"GO:0140493"(very long-chain fatty acid beta-oxidation)|interpro:IPR002655(Acyl-CoA oxidase, C-terminal)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR012258(Acyl-CoA oxidase)|interpro:IPR029320|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR034171|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-1989781|reactome:R-HSA-2046106|reactome:R-HSA-390247|reactome:R-HSA-9033241|reactome:R-HSA-9033500|refseq:NP_001171968.1|refseq:NP_004026.2|refseq:NP_009223.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:nmFzdfUulW0CSpRLqXcetLzLvwk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q14410	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943426|ensembl:ENSP00000351706|uniprotkb:A8K876|uniprotkb:Q6PD73|uniprotkb:Q86XV8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:glpk2_human(display_long)|uniprotkb:GK2(gene name)|psi-mi:GK2(display_short)|uniprotkb:"ATP:glycerol 3-phosphotransferase 2"(gene name synonym)|uniprotkb:GKP2(gene name synonym)|uniprotkb:GKTA(gene name synonym)|uniprotkb:Glycerol kinase, testis specific 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000196475(gene)|ensembl:ENST00000358842(transcript)|go:"GO:0004370"(glycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0016310"(phosphorylation)|refseq:NP_149991.2|go:"GO:0016773"(phosphotransferase activity, alcohol group as acceptor)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0046167"(glycerol-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000577(Carbohydrate kinase, FGGY)|interpro:IPR005999(Glycerol kinase)|interpro:IPR018483|interpro:IPR018484|interpro:IPR018485|interpro:IPR042018|interpro:IPR043129|reactome:R-HSA-75109	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:o5ALoBEM8QWVnfzZnPYhW5TbbtA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96RT1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-993903|uniprotkb:Q86W38|uniprotkb:Q9NR18|uniprotkb:Q9NW48|uniprotkb:Q9ULJ5|ensembl:ENSP00000284037|uniprotkb:A0AVR1|uniprotkb:B4E3F1|uniprotkb:B7ZLV9|uniprotkb:E9PCR8|uniprotkb:Q1RMD0|uniprotkb:E7EQW9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:erbin_human(display_long)|uniprotkb:ERBIN(gene name)|psi-mi:ERBIN(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:ERBB2IP(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:KIAA1225(gene name synonym)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001240628.1|refseq:NP_001240630.1|ensembl:ENSG00000112851(gene)|ensembl:ENST00000284037(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045175"(basal protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR032927|interpro:IPR036034|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1N7T|rcsb pdb:2H3L|rcsb pdb:2QBW|rcsb pdb:3CH8|rcsb pdb:6Q0M|rcsb pdb:6Q0N|rcsb pdb:6Q0U|rcsb pdb:6UBG|rcsb pdb:6UBH|reactome:R-HSA-1227986|reactome:R-HSA-8863795|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013408|reactome:R-HSA-9013106|reactome:R-HSA-9013423|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|refseq:NP_001006600.1|refseq:NP_061165.1|refseq:NP_001240626.1|refseq:NP_001240627.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:kITHWAgafb7t7RFgzs5ff7XCL3Y9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15390	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-724207|ensembl:ENSP00000262146|uniprotkb:Q6IB94|uniprotkb:Q86XH5|uniprotkb:Q8IVD7|uniprotkb:E7EP84|uniprotkb:Q7Z669	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mtfr1_human(display_long)|uniprotkb:Chondrocyte protein with a poly-proline region(gene name synonym)|uniprotkb:MTFR1(gene name)|psi-mi:MTFR1(display_short)|uniprotkb:CHPPR(gene name synonym)|uniprotkb:KIAA0009(gene name synonym)|uniprotkb:FAM54A2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001139310.1|refseq:NP_055452.3|ensembl:ENSG00000066855(gene)|ensembl:ENST00000262146(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009060"(aerobic respiration)|interpro:IPR007972(Protein of unknown function DUF729)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:JVlx6NDlSs6KbMdpHuZw0rzmY2o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UDX5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1042890|uniprotkb:Q9H3K1|uniprotkb:Q9P0N6|uniprotkb:A6NFQ5|ensembl:ENSP00000266263	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mtfp1_human(display_long)|uniprotkb:MTFP1(gene name)|psi-mi:MTFP1(display_short)|uniprotkb:HSPC242(orf name)|uniprotkb:My022(orf name)|uniprotkb:Mitochondrial 18 kDa protein(gene name synonym)|uniprotkb:MTP18(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000242114(gene)|ensembl:ENST00000266263(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR019560|refseq:NP_001003704.1|refseq:NP_057582.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ALtZgmbrJPk5pO2HT0pegGWmTLc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6PGP7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6083436|uniprotkb:O15077|uniprotkb:Q6PJI3|ensembl:ENSP00000351596|ensembl:ENSP00000497948	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ttc37_human(display_long)|uniprotkb:Tricho-hepatic-enteric syndrome protein(gene name synonym)|uniprotkb:SKI3 homolog(gene name synonym)|uniprotkb:TTC37(gene name)|psi-mi:TTC37(display_short)|uniprotkb:KIAA0372(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055454.1|ensembl:ENSG00000198677(gene)|ensembl:ENST00000358746(transcript)|ensembl:ENST00000649566(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0035327"|go:"GO:0055087"(Ski complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|mint:Q6PGP7|reactome:R-HSA-429958	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:1vbt+NR8Vmwq7a+9fisoF2WxDbc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96D53	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3957978|uniprotkb:Q8TAJ1|uniprotkb:Q9HA52|ensembl:ENSP00000315118|ensembl:ENSP00000470876|ensembl:ENSP00000470916|ensembl:ENSP00000503480|ensembl:ENSP00000503944|ensembl:ENSP00000504072|ensembl:ENSP00000504085|ensembl:ENSP00000504845	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:coq8b_human(display_long)|uniprotkb:COQ8B(gene name)|psi-mi:COQ8B(display_short)|uniprotkb:ADCK4(gene name synonym)|uniprotkb:AarF domain-containing protein kinase 4(gene name synonym)|uniprotkb:Coenzyme Q protein 8B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001136027.1|refseq:NP_079152.3|ensembl:ENSG00000123815(gene)|ensembl:ENST00000324464(transcript)|ensembl:ENST00000594720(transcript)|ensembl:ENST00000601967(transcript)|ensembl:ENST00000677018(transcript)|ensembl:ENST00000678404(transcript)|ensembl:ENST00000678419(transcript)|ensembl:ENST00000678467(transcript)|ensembl:ENST00000679130(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034638|interpro:IPR034646|mint:Q96D53	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:UAfHqMHShcF12Ijycxi7OWs0KFE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N122	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1567928|uniprotkb:Q8N4V9|uniprotkb:Q8TB32|uniprotkb:Q9P2P3|uniprotkb:B2RN36|uniprotkb:C6KEF2|uniprotkb:F5H7J5|ensembl:ENSP00000307272	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rptor_human(display_long)|uniprotkb:"p150 target of rapamycin (TOR)-scaffold protein"(gene name synonym)|uniprotkb:RPTOR(gene name)|psi-mi:RPTOR(display_short)|uniprotkb:KIAA1303(gene name synonym)|uniprotkb:RAPTOR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001156506.1|refseq:NP_065812.1|dip:DIP-39482N|ensembl:ENSG00000141564(gene)|ensembl:ENST00000306801(transcript)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009410"(response to xenobiotic stimulus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0031929"(TOR signaling)|go:"GO:0031931"(TORC1 complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000357(HEAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR004083(Regulatory associated protein of TOR)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029347|interpro:IPR036322|mint:Q8N122|rcsb pdb:5H64|rcsb pdb:6BCU|rcsb pdb:6BCX|rcsb pdb:6SB0|rcsb pdb:6SB2|rcsb pdb:6U62|reactome:R-HSA-1632852|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-3371571|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-8943724|reactome:R-HSA-9639288	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:BOvNcQXqn9hLPxAZeCZhKWbwgOk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15363	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-998485|ensembl:ENSP00000262225	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tmed2_human(display_long)|uniprotkb:TMED2(gene name)|psi-mi:TMED2(display_short)|uniprotkb:RNP24(gene name synonym)|uniprotkb:Membrane protein p24A(gene name synonym)|uniprotkb:p24 family protein beta-1(gene name synonym)|uniprotkb:p24(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000086598(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001843"(neural tube closure)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001947"(heart looping)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|ensembl:ENST00000262225(transcript)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060717"(chorion development)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:1905069"(allantois development)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|rcsb pdb:5AZW|reactome:R-HSA-1912420|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|refseq:NP_001308374.1|reactome:R-HSA-6811434|refseq:NP_006806.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TKdrbEIvtqutTXM3C6UcmMQU0eQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NUQ2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6916385|ensembl:ENSP00000285518|ensembl:ENSP00000495562|uniprotkb:Q8IZ47|uniprotkb:Q9BQG4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:plce_human(display_long)|uniprotkb:AGPAT5(gene name)|psi-mi:AGPAT5(display_short)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase 5(gene name synonym)|uniprotkb:Lysophosphatidic acid acyltransferase epsilon(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000155189(gene)|ensembl:ENSG00000284980(gene)|ensembl:ENST00000285518(transcript)|ensembl:ENST00000646327(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006639"(acylglycerol metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0016746"(acyltransferase activity)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR032098|reactome:R-HSA-1483166|refseq:NP_060831.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Osmz6W9W0rS+khEYpiVNvL14S/I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P51617	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358664|uniprotkb:Q7Z5V4|uniprotkb:Q96RL2|intact:EBI-28987029|ensembl:ENSP00000358997|uniprotkb:D3DWW4|uniprotkb:D3DWW3|uniprotkb:Q96C06	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:irak1_human(display_long)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:P51617|rcsb pdb:6BFN|ensembl:ENSG00000184216(gene)|ensembl:ENST00000369980(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007568"(aging)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|refseq:NP_001020413.1|refseq:NP_001020414.1|refseq:NP_001560.2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-6811558|reactome:R-HSA-8986944|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975871|ensembl:ENST00000369974|ensembl:ENSP00000358997|ensembl:ENST00000393687|ensembl:ENSP00000377291|ensembl:ENSP00000358991|dip:DIP-397N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:q+oAzeVuuQvO24HkoHx6PKK7XUY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9ULX3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-373285|uniprotkb:Q7L6B7|uniprotkb:Q7M4M4|uniprotkb:Q7Z4B5|uniprotkb:Q9NWB0|ensembl:ENSP00000268802	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nob1_human(display_long)|uniprotkb:NOB1(gene name)|psi-mi:NOB1(display_short)|uniprotkb:Protein ART-4(gene name synonym)|uniprotkb:Phosphorylation regulatory protein HP-10(gene name synonym)|uniprotkb:ART4(gene name synonym)|uniprotkb:NOB1P(gene name synonym)|uniprotkb:PSMD8BP1(gene name synonym)|uniprotkb:MSTP158(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_054781.1|ensembl:ENSG00000141101(gene)|ensembl:ENST00000268802(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0007601"(visual perception)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0046872"(metal ion binding)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR014881("Nin one binding (NOB1) Zn-ribbon like")|interpro:IPR017117(D-site 20S pre-rRNA nuclease)|interpro:IPR033411|interpro:IPR033461|interpro:IPR036283|interpro:IPR039907|mint:Q9ULX3|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|reactome:R-HSA-6791226	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/Xk2PcxpyxjcG5gvs2VtLK6QmvA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P24390	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043076|uniprotkb:B2R6N4|ensembl:ENSP00000329471|uniprotkb:Q54A39|uniprotkb:Q8NBW7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:erd21_human(display_long)|uniprotkb:KDELR1(gene name)|psi-mi:KDELR1(display_short)|uniprotkb:ERD2.1(gene name synonym)|uniprotkb:KDEL endoplasmic reticulum protein retention receptor 1(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000105438(gene)|ensembl:ENST00000330720(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005046"(KDEL sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046923"(ER retention sequence binding)|go:"GO:0070231"(T cell apoptotic process)|interpro:IPR000133(ER lumen protein retaining receptor)|mint:P24390|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_006792.1|dip:DIP-48668N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:V+4Hb765BqjFuT1/ewZWs9gNQ/M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95822	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10714916|uniprotkb:Q9UNU5|uniprotkb:Q9Y3F2|ensembl:ENSP00000262430	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dcmc_human(display_long)|uniprotkb:MLYCD(gene name)|psi-mi:MLYCD(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_036345.2|ensembl:ENSG00000103150(gene)|ensembl:ENST00000262430(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046321"(positive regulation of fatty acid oxidation)|go:"GO:0050080"(malonyl-CoA decarboxylase activity)|go:"GO:2001294"(malonyl-CoA catabolic process)|interpro:IPR007956(Malonyl-CoA decarboxylase)|interpro:IPR035372|interpro:IPR038351|interpro:IPR038917|interpro:IPR042303|rcsb pdb:2YGW|rcsb pdb:4F0X|reactome:R-HSA-390247|reactome:R-HSA-9033241|dip:DIP-60405N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8wCYyrLE10zXVn0GPBiZUsPUp2o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15258	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-716910|uniprotkb:O95322|ensembl:ENSP00000464222|ensembl:ENSP00000475168	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rer1_human(display_long)|uniprotkb:RER1(gene name)|psi-mi:RER1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_008964.3|refseq:XP_011538844.1|refseq:XP_011538845.1|refseq:XP_006710369.1|ensembl:ENSG00000157916(gene)|ensembl:ENST00000488353(transcript)|ensembl:ENST00000605895(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009986"(cell surface)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR004932(Retrieval of early ER protein Rer1)|mint:O15258|refseq:XP_016855622.1|refseq:XP_016855623.1|refseq:XP_016855624.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:rLTZIWGawmaVck0uemR5/E9bFRk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8WU76	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2561361|ensembl:ENSP00000384182|uniprotkb:Q8N5F3|uniprotkb:Q96ED3|uniprotkb:Q8N8H0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:scfd2_human(display_long)|uniprotkb:SCFD2(gene name)|psi-mi:SCFD2(display_short)|uniprotkb:STXBP1L1(gene name synonym)|uniprotkb:Syntaxin-binding protein 1-like 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000184178(gene)|ensembl:ENST00000401642(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|refseq:NP_689753.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TaNn58iCMGPAhs6k76eLY0BuGKM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y5L0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1042571|uniprotkb:A4D1K9|uniprotkb:Q6NUM1|uniprotkb:Q96G71|uniprotkb:Q96GU9|uniprotkb:Q9Y3R2|uniprotkb:C9IZM0|ensembl:ENSP00000265388	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tnpo3_human(display_long)|uniprotkb:TNPO3(gene name)|psi-mi:TNPO3(display_short)|uniprotkb:IPO12(gene name synonym)|uniprotkb:Transportin-SR(gene name synonym)|uniprotkb:Importin-12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001177957.2|refseq:NP_036602.1|ensembl:ENSG00000064419(gene)|ensembl:ENST00000265388(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y5L0|rcsb pdb:4C0O|rcsb pdb:4C0P|rcsb pdb:4C0Q|rcsb pdb:4OL0|rcsb pdb:6GX9	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Xvd5fZ4wlMc6R6w2wL+JhIOOuIE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q68CZ6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P23368	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043318|uniprotkb:Q9H4B2|uniprotkb:Q9BYG1|ensembl:ENSP00000321070|uniprotkb:B2R8J2|uniprotkb:Q9BWL6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:maom_human(display_long)|uniprotkb:Malic enzyme 2(gene name synonym)|uniprotkb:ME2(gene name)|psi-mi:ME2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001161807.1|rcsb pdb:1QR6|rcsb pdb:7BSJ|rcsb pdb:7BSK|rcsb pdb:7BSL|reactome:R-HSA-71403|ensembl:ENST00000321341(transcript)|go:"GO:0004470"(malic enzyme activity)|go:"GO:0004471"("malate dehydrogenase (decarboxylating) (NAD+) activity")|go:"GO:0004473"("malate dehydrogenase (decarboxylating) (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006108"(malate metabolic process)|ensembl:ENSG00000082212(gene)|go:"GO:0008948"(oxaloacetate decarboxylase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:1902031"(regulation of NADP metabolic process)|interpro:IPR001891(Malic oxidoreductase)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR036291|interpro:IPR037062|mint:P23368|rcsb pdb:1DO8|rcsb pdb:1EFK|rcsb pdb:1EFL|rcsb pdb:1GZ3|rcsb pdb:1GZ4|rcsb pdb:1PJ2|rcsb pdb:1PJ3|rcsb pdb:1PJ4|rcsb pdb:1PJL|refseq:NP_002387.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:aJAm/VMhqHLF07K3FlystextLrc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BT40	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-749162|uniprotkb:Q15733|uniprotkb:Q9NPJ5|uniprotkb:Q9P2R5|uniprotkb:B2R6I2|uniprotkb:B2R750|uniprotkb:D3DTH8|intact:EBI-28986464|ensembl:ENSP00000413937	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:inp5k_human(display_long)|uniprotkb:SKIP(gene name synonym)|uniprotkb:Skeletal muscle and kidney-enriched inositol phosphatase(gene name synonym)|uniprotkb:INPP5K(gene name)|psi-mi:INPP5K(display_short)|uniprotkb:PPS(gene name synonym)|uniprotkb:Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-4,5-bisphosphate 5-phosphatase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001129114.1|refseq:NP_057616.2|refseq:NP_570122.1|refseq:XP_011522236.1|ensembl:ENST00000320345|ensembl:ENSP00000318476|ensembl:ENST00000406424|ensembl:ENSP00000385177|ensembl:ENSP00000413937|refseq:XP_005256740.1|refseq:XP_016880244.1|refseq:XP_016880245.1|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016312"(inositol bisphosphate phosphatase activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0034594"(phosphatidylinositol trisphosphate phosphatase activity)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043005"(neuron projection)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046030"(inositol trisphosphate phosphatase activity)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0052659"(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|go:"GO:0097178"(ruffle assembly)|go:"GO:2000466"("negative regulation of glycogen (starch) synthase activity")|go:"GO:2001153"(positive regulation of renal water transport)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|interpro:IPR041611|reactome:R-HSA-1660499|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|ensembl:ENSG00000132376(gene)|ensembl:ENST00000421807(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005000"(vasopressin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8QwPQ6eR07CZ8XlPtkdG60+KFNA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BWF3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2856454|uniprotkb:B3KUN0|uniprotkb:Q8WU85|uniprotkb:Q6P1P2|uniprotkb:O02916|uniprotkb:Q4VC48|uniprotkb:B4E1U0|uniprotkb:E7EQS3|ensembl:ENSP00000309166|ensembl:ENSP00000386561|ensembl:ENSP00000386894	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rbm4_human(display_long)|uniprotkb:RBM4(gene name)|psi-mi:RBM4(display_short)|uniprotkb:RBM4A(gene name synonym)|uniprotkb:Lark homolog(gene name synonym)|uniprotkb:RNA-binding motif protein 4(gene name synonym)|uniprotkb:RNA-binding motif protein 4a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001185772.1|refseq:NP_002887.2|refseq:NP_001185773.1|dip:DIP-44199N|ensembl:ENSG00000173933(gene)|ensembl:ENST00000310092(transcript)|ensembl:ENST00000408993(transcript)|ensembl:ENST00000409406(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002190"(cap-independent translational initiation)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:0097167"(circadian regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979|mint:Q9BWF3|rcsb pdb:2DNQ|reactome:R-HSA-400253|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:hbW6dv/AEWQz3mWvA2/9n8h/bbA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:B8ZZA8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943424|ensembl:ENSP00000386417	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:b8zza8_human(display_long)|uniprotkb:GLS(gene name)|psi-mi:GLS(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000115419(gene)|ensembl:ENST00000409626(transcript)|go:"GO:0004359"(glutaminase activity)|go:"GO:0006541"(glutamine metabolic process)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4DjQd2zpyf6GqrwRUW5++ej50/09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UHW5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-395491|uniprotkb:Q53FS3|uniprotkb:Q6UVZ6|uniprotkb:Q7Z3D3|uniprotkb:Q8NEI2|uniprotkb:Q96HK9|uniprotkb:B2RC54|uniprotkb:D4YWV1|ensembl:ENSP00000228827|uniprotkb:F5H759	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gpn3_human(display_long)|uniprotkb:ATPBD1C(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:AD-009(orf name)|uniprotkb:UNQ1876/PRO4319(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001157844.1|refseq:NP_001157845.1|refseq:NP_057385.3|ensembl:ENSG00000111231(gene)|ensembl:ENST00000228827(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|mint:Q9UHW5	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fKBsnLcvitaM76zQUW+MQXDPxTA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43169	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y3E5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1056751|uniprotkb:Q9NTE5|uniprotkb:B3KUY4|ensembl:ENSP00000376758|ensembl:ENSP00000464327	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pth2_human(display_long)|uniprotkb:PTRH2(gene name)|psi-mi:PTRH2(display_short)|uniprotkb:BIT1(gene name synonym)|uniprotkb:PTH2(gene name synonym)|uniprotkb:CGI-147(orf name)|uniprotkb:Bcl-2 inhibitor of transcription 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057161.1|refseq:NP_001015509.1|refseq:XP_011523189.1|ensembl:ENSG00000141378(gene)|ensembl:ENST00000393038(transcript)|ensembl:ENST00000470557(transcript)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:2000210"(positive regulation of anoikis)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002833(Peptidyl-tRNA hydrolase, PTH2)|interpro:IPR023476|mint:Q9Y3E5|rcsb pdb:1Q7S|reactome:R-HSA-5689880	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:E0QOhTNtGBt5CQ3gPebnOhoKvdU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P23786	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6269566|ensembl:ENSP00000360541|uniprotkb:B2R6S0|uniprotkb:Q5SW68|uniprotkb:Q9BQ26	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cpt2_human(display_long)|uniprotkb:CPT2(gene name)|psi-mi:CPT2(display_short)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000157184(gene)|ensembl:ENST00000371486(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006853"(carnitine shuttle)|go:"GO:0008458"(carnitine O-octanoyltransferase activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042572|reactome:R-HSA-1989781|reactome:R-HSA-200425|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|refseq:NP_000089.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:maFH51Fz1PYXUzBwLPr3sGlVkcY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H7Z7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-681645|uniprotkb:Q53EW9|uniprotkb:Q5SYV6|uniprotkb:Q96GI0|uniprotkb:Q96GL2|ensembl:ENSP00000345341	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pges2_human(display_long)|uniprotkb:Microsomal prostaglandin E synthase 2(gene name synonym)|uniprotkb:PTGES2(gene name)|psi-mi:PTGES2(display_short)|uniprotkb:PGES2(gene name synonym)|uniprotkb:C9orf15(gene name synonym)|uniprotkb:Membrane-associated prostaglandin E synthase-2(gene name synonym)|uniprotkb:"Prostaglandin-H(2) E-isomerase"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001243264.1|refseq:NP_079348.1|refseq:NP_945176.1|ensembl:ENSG00000148334(gene)|ensembl:ENST00000338961(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016829"(lyase activity)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0020037"(heme binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036134"(12-hydroxyheptadecatrienoic acid synthase activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050220"(prostaglandin-E synthase activity)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR034334|interpro:IPR034335|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:Q9H7Z7|reactome:R-HSA-2162123|reactome:R-HSA-6798695	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DFALgQTHlFSBHZUZBKTJNxxSqjk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NZJ7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-297455|ensembl:ENSP00000362730|uniprotkb:Q6PK60|uniprotkb:Q6UX45|uniprotkb:Q7L465|uniprotkb:Q9BW23|uniprotkb:Q9NZR6|uniprotkb:Q9UJZ5|uniprotkb:B2RCE3|uniprotkb:A8KAX5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mtch1_human(display_long)|uniprotkb:Presenilin-associated protein(gene name synonym)|uniprotkb:CGI-64(orf name)|uniprotkb:MTCH1(gene name)|psi-mi:MTCH1(display_short)|uniprotkb:PSAP(gene name synonym)|uniprotkb:UNQ1871/PRO4314(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000137409(gene)|ensembl:ENST00000373627(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045161"(neuronal ion channel clustering)|interpro:IPR018108|interpro:IPR023395|mint:Q9NZJ7|refseq:NP_055156.1|refseq:NP_001258570.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:I0J5CxSiLB4OS6mhqwygLq389xY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BTE7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3924013|uniprotkb:Q3ZTT2|ensembl:ENSP00000260247	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dcnl5_human(display_long)|uniprotkb:DCUN1D5(gene name)|psi-mi:DCUN1D5(display_short)|uniprotkb:DCUN1 domain-containing protein 5(gene name synonym)|uniprotkb:Defective in cullin neddylation protein 1-like protein 5(gene name synonym)|uniprotkb:SCCRO5(gene name synonym)|uniprotkb:Squamous cell carcinoma-related oncogene 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_115675.1|ensembl:ENST00000260247(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032182"(ubiquitin-like protein binding)|go:"GO:0045116"(protein neddylation)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2000436"(positive regulation of protein neddylation)|interpro:IPR005176(Protein of unknown function DUF298)|interpro:IPR014764(Defective in cullin neddylation)|interpro:IPR042460|reactome:R-HSA-8951664|ensembl:ENSG00000137692(gene)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:EDYg7Tn8nZY4IPid4ZckCJ3e20M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y3D6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3385283|ensembl:ENSP00000223136|uniprotkb:Q9BTP3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:fis1_human(display_long)|uniprotkb:FIS1(gene name)|psi-mi:FIS1(display_short)|uniprotkb:TTC11(gene name synonym)|uniprotkb:FIS1 homolog(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 11(gene name synonym)|uniprotkb:CGI-135(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000214253(gene)|ensembl:ENST00000223136(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042802"(identical protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902617"(response to fluoride)|go:"GO:1903579"(negative regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000192"(negative regulation of fatty acid transport)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016543(Tetratricopeptide repeat 11 Fission 1 protein)|interpro:IPR028058|interpro:IPR028061|interpro:IPR033745|mint:Q9Y3D6|rcsb pdb:1NZN|rcsb pdb:1PC2|reactome:R-HSA-9603798|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|refseq:NP_057152.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5YzrFokAQLKvMCqzS12qalQtu489606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43823	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1237481|ensembl:ENSP00000269701	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:akap8_human(display_long)|uniprotkb:AKAP8(gene name)|psi-mi:AKAP8(display_short)|uniprotkb:AKAP95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005849.1|dip:DIP-38194N|ensembl:ENSG00000105127(gene)|ensembl:ENST00000269701(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:O43823|go:"GO:0051059"(NF-kappaB binding)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VtRlGSvkRqrzAcnq2Fj6fToZifY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75891	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10714847|uniprotkb:B4DG36|uniprotkb:E9PBX3|uniprotkb:Q68CS1|uniprotkb:Q8TBP8|ensembl:ENSP00000377083|ensembl:ENSP00000420293	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:al1l1_human(display_long)|uniprotkb:Aldehyde dehydrogenase family 1 member L1(gene name synonym)|uniprotkb:ALDH1L1(gene name)|psi-mi:ALDH1L1(display_short)|uniprotkb:FTHFD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001257293.1|refseq:NP_001257294.1|refseq:NP_036322.2|refseq:XP_006713544.1|refseq:XP_011510657.1|ensembl:ENSG00000144908(gene)|ensembl:ENST00000393434(transcript)|ensembl:ENST00000472186(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009258"(10-formyltetrahydrofolate catabolic process)|go:"GO:0016155"(formyltetrahydrofolate dehydrogenase activity)|go:"GO:0016742"(hydroxymethyl-, formyl- and related transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR011407(10-formyltetrahydrofolate dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|interpro:IPR036477|interpro:IPR036736|interpro:IPR037022|rcsb pdb:2BW0|rcsb pdb:2CFI|rcsb pdb:2CQ8|reactome:R-HSA-196757	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8ixKith6JQNu3p5I1XqwgeRYfwc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UM00	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1051217|uniprotkb:O75545|uniprotkb:Q9BZS3|uniprotkb:Q9BZU8|uniprotkb:B2REA0|ensembl:ENSP00000480514|uniprotkb:J9JIE6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tmco1_human(display_long)|uniprotkb:Transmembrane and coiled-coil domain-containing protein 1(gene name synonym)|uniprotkb:Xenogeneic cross-immune protein PCIA3(gene name synonym)|uniprotkb:Transmembrane and coiled-coil domains protein 4(gene name synonym)|uniprotkb:TMCO1(gene name)|psi-mi:TMCO1(display_short)|uniprotkb:PNAS-10(orf name)|uniprotkb:PNAS-136(orf name)|uniprotkb:UNQ151/PRO177(orf name)|uniprotkb:TMCC4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_061899.2|ensembl:ENSG00000143183(gene)|ensembl:ENST00000612311(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006983"(ER overload response)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0043022"(ribosome binding)|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008559(Protein of unknown function DUF841, eukaryotic)|rcsb pdb:6W6L	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:AGRI6UgUEOjrVCi0laVQPtfaHRU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P08574	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1224514|uniprotkb:Q5U062|uniprotkb:Q6FHS7|ensembl:ENSP00000317159	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cy1_human(display_long)|uniprotkb:CYC1(gene name)|psi-mi:CYC1(display_short)|uniprotkb:Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 4(gene name synonym)|uniprotkb:Complex III subunit 4(gene name synonym)|uniprotkb:Complex III subunit IV(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001907.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0033762"(response to glucagon)|go:"GO:0046872"(metal ion binding)|interpro:IPR002326(Cytochrome c1)|interpro:IPR021157|interpro:IPR036909|mint:P08574|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|ensembl:ENSG00000179091(gene)|ensembl:ENST00000318911(transcript)|go:"GO:0005634"(nucleus)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:WFFFejEobb6Uoum311x+fry5X+o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P42765	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2852639|uniprotkb:Q9BUT6|ensembl:ENSP00000285093	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:thim_human(display_long)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:ACAA2(gene name)|psi-mi:ACAA2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:T1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006102.2|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P42765|rcsb pdb:4C2J|rcsb pdb:4C2K|reactome:R-HSA-77289|interpro:IPR020613|ensembl:ENSG00000167315(gene)|ensembl:ENST00000285093(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TJMFLcEB5eKz36plSuUiteAJN9g9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5SWX8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2828345|uniprotkb:Q9NX06|uniprotkb:Q8WYB6|uniprotkb:Q9BTS2|uniprotkb:Q9H6A6|uniprotkb:Q19CC6|uniprotkb:B4DNY0|uniprotkb:E9PFR7|ensembl:ENSP00000287859	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:odr4_human(display_long)|uniprotkb:ODR4(gene name)|psi-mi:ODR4(display_short)|uniprotkb:C1orf27(gene name synonym)|uniprotkb:TTG1(gene name synonym)|uniprotkb:TTG1A(gene name synonym)|uniprotkb:LAG1-interacting protein(gene name synonym)|uniprotkb:Transactivated by transforming growth factor beta protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011507962.1|refseq:NP_001157717.1|refseq:NP_001157718.1|refseq:NP_060317.3|ensembl:ENSG00000157181(gene)|ensembl:ENST00000287859(transcript)|go:"GO:0008104"(protein localization)|go:"GO:0016021"(integral component of membrane)|interpro:IPR029454	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3hRM77WnSLum546leakN3rYhRJs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NE86	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6552124|ensembl:ENSP00000362144|uniprotkb:B2RDF3|uniprotkb:B3KXV7|uniprotkb:Q96FL3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mcu_human(display_long)|uniprotkb:MCU(gene name)|psi-mi:MCU(display_short)|uniprotkb:C10orf42(gene name synonym)|uniprotkb:CCDC109A(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 109A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1990246"(uniplex complex)|interpro:IPR006769(Protein of unknown function DUF607)|interpro:IPR039055|rcsb pdb:4XSJ|rcsb pdb:4XTB|rcsb pdb:5BZ6|rcsb pdb:5KUE|rcsb pdb:5KUG|rcsb pdb:5KUI|rcsb pdb:5KUJ|rcsb pdb:6JG0|rcsb pdb:6K7X|rcsb pdb:6K7Y|rcsb pdb:6KVX|rcsb pdb:6O58|rcsb pdb:6O5B|rcsb pdb:6WDN|rcsb pdb:6WDO|rcsb pdb:6XJV|rcsb pdb:6XJX|reactome:R-HSA-8949215|reactome:R-HSA-8949664|go:"GO:0019722"(calcium-mediated signaling)|ensembl:ENSG00000156026(gene)|ensembl:ENST00000373053(transcript)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0015292"(uniporter activity)|refseq:NP_001257608.1|refseq:NP_001257609.1|refseq:NP_612366.1|dip:DIP-60468N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:t2fSATmrk7IEC0nMpquAoPB3CHs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NR56	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2805004|uniprotkb:O43797|uniprotkb:O43311|uniprotkb:Q86UV8|uniprotkb:Q96P92|uniprotkb:Q96RE3|uniprotkb:E9PBW7|uniprotkb:Q86UV9|ensembl:ENSP00000282486|ensembl:ENSP00000418108	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mbnl1_human(display_long)|uniprotkb:EXP(gene name synonym)|uniprotkb:KIAA0428(gene name synonym)|uniprotkb:MBNL(gene name synonym)|uniprotkb:Triplet-expansion RNA-binding protein(gene name synonym)|uniprotkb:MBNL1(gene name)|psi-mi:MBNL1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011511149.1|refseq:XP_011511151.1|refseq:NP_001300986.1|refseq:NP_066368.2|refseq:NP_997175.1|refseq:NP_997176.1|refseq:NP_997177.1|refseq:NP_997178.1|refseq:NP_997179.1|refseq:NP_997180.1|refseq:XP_005247523.1|refseq:XP_005247528.1|ensembl:ENSP00000282486|ensembl:ENST00000324196|ensembl:ENSP00000319374|ensembl:ENST00000324210|ensembl:ENSP00000319429|ensembl:ENST00000355460|ensembl:ENSP00000347637|ensembl:ENST00000357472|ensembl:ENSP00000350064|ensembl:ENSP00000418108|ensembl:ENST00000465907|ensembl:ENSP00000417630|ensembl:ENST00000485509|ensembl:ENSP00000418876|ensembl:ENST00000485910|ensembl:ENSP00000418427|ensembl:ENST00000492948|ensembl:ENSP00000420103|ensembl:ENST00000545754|ensembl:ENSP00000437491|interpro:IPR000571(Zinc finger, CCCH-type)|mint:Q9NR56|rcsb pdb:3D2N|rcsb pdb:3D2Q|rcsb pdb:3D2S|rcsb pdb:5U6H|rcsb pdb:5U6L|rcsb pdb:5U9B|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000152601(gene)|ensembl:ENST00000282486(transcript)|ensembl:ENST00000463374(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007399"(nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045445"(myoblast differentiation)|refseq:XP_016861914.1|refseq:XP_016861915.1|refseq:XP_016861916.1|refseq:XP_016861917.1|refseq:XP_016861918.1|refseq:XP_016861919.1|refseq:XP_016861920.1|refseq:XP_016861925.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:uvyDik76f41mvxO2j/dUD6mKMOk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P35914	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-721399|uniprotkb:B7UCC6|uniprotkb:D3Y5K7|uniprotkb:Q6IBC0|uniprotkb:Q96FP8|uniprotkb:B4DUP4|ensembl:ENSP00000363614	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hmgcl_human(display_long)|uniprotkb:3-hydroxy-3-methylglutarate-CoA lyase(gene name synonym)|uniprotkb:HMGCL(gene name)|psi-mi:HMGCL(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000182.2|refseq:NP_001159531.1|ensembl:ENSG00000117305(gene)|ensembl:ENST00000374490(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001889"(liver development)|go:"GO:0004419"(hydroxymethylglutaryl-CoA lyase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007584"(response to nutrient)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042594"(response to starvation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046951"(ketone body biosynthetic process)|go:"GO:0070542"(response to fatty acid)|interpro:IPR000138(Hydroxymethylglutaryl-CoA lyase, active site)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR043594|rcsb pdb:2CW6|rcsb pdb:3MP3|rcsb pdb:3MP4|rcsb pdb:3MP5|reactome:R-HSA-77111|reactome:R-HSA-9033241	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5MeWxi06/Ygl18C8UpZKlf9tJc09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15173	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425|ensembl:ENSP00000429301	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006311.2|ensembl:ENSG00000164040(gene)|ensembl:ENST00000296425(transcript)|ensembl:ENST00000520121(transcript)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96AB3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-372799|uniprotkb:Q9H5G0|uniprotkb:Q6ZN91|ensembl:ENSP00000401726	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:isoc2_human(display_long)|uniprotkb:ISOC2(gene name)|psi-mi:ISOC2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001129673.1|refseq:NP_001129674.1|refseq:NP_078986.1|ensembl:ENSG00000063241(gene)|ensembl:ENST00000425675(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031648"(protein destabilization)|interpro:IPR000868(Isochorismatase hydrolase)|interpro:IPR036380|interpro:IPR040318	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/529kybU6ZrjgYKx6adgIJCb3fE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6IAN0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-725639|uniprotkb:B5MEF4|uniprotkb:Q6UX59|uniprotkb:Q9BTF9|uniprotkb:Q9UFM6|uniprotkb:Q9Y3A1|ensembl:ENSP00000378887	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:drs7b_human(display_long)|uniprotkb:DHRS7B(gene name)|psi-mi:DHRS7B(display_short)|uniprotkb:SDR32C1(gene name synonym)|uniprotkb:Short-chain dehydrogenase/reductase family 32C member 1(gene name synonym)|uniprotkb:CGI-93(orf name)|uniprotkb:UNQ212/PRO238(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056325.2|ensembl:ENSG00000109016(gene)|ensembl:ENST00000395511(transcript)|go:"GO:0000140"(acylglycerone-phosphate reductase activity)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|reactome:R-HSA-75896|refseq:NP_001317088.1|refseq:XP_016879915.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qGu2N6bspgbSJE+AIL0Xeh6b0J49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P00387	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1046040|uniprotkb:O75675|uniprotkb:Q8TDL8|uniprotkb:Q8WTS8|uniprotkb:Q9UEN4|uniprotkb:Q9UEN5|uniprotkb:Q9UL55|uniprotkb:Q9UL56|uniprotkb:B1AHF2|uniprotkb:B7Z7L3|ensembl:ENSP00000338461	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nb5r3_human(display_long)|uniprotkb:Diaphorase-1(gene name synonym)|uniprotkb:CYB5R3(gene name)|psi-mi:CYB5R3(display_short)|uniprotkb:DIA1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001165132.1|refseq:NP_000389.1|refseq:NP_001123291.1|refseq:NP_015565.1|refseq:NP_001165131.1|ensembl:ENSG00000100243(gene)|ensembl:ENST00000352397(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008015"(blood circulation)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043531"(ADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|mint:P00387|rcsb pdb:1M91|rcsb pdb:1UMK|reactome:R-HSA-196836|reactome:R-HSA-211945|reactome:R-HSA-6798695|interpro:IPR039261|dip:DIP-50463N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Q8JTO6AXZ8LE4FXZAzOw2p4b6HY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6P587	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-597013|uniprotkb:Q6FIC7|uniprotkb:Q96RY1|uniprotkb:Q9H0N6|uniprotkb:B1AK41|uniprotkb:B1AK40|ensembl:ENSP00000398053	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:fahd1_human(display_long)|uniprotkb:FAHD1(gene name)|psi-mi:FAHD1(display_short)|uniprotkb:C16orf36(gene name synonym)|uniprotkb:Fumarylacetoacetate hydrolase domain-containing protein 1(gene name synonym)|uniprotkb:YISKL(gene name synonym)|uniprotkb:YisK-like protein(gene name synonym)|uniprotkb:Oxaloacetate decarboxylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001018114.1|refseq:NP_001135870.1|refseq:NP_112485.1|ensembl:ENSG00000180185(gene)|ensembl:ENST00000427358(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008948"(oxaloacetate decarboxylase activity)|go:"GO:0018773"(acetylpyruvate hydrolase activity)|go:"GO:0034545"(fumarylpyruvate hydrolase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047621"(acylpyruvate hydrolase activity)|interpro:IPR011234(Fumarylacetoacetase, C-terminal-related)|interpro:IPR036663|rcsb pdb:1SAW|rcsb pdb:6FOG|rcsb pdb:6FOH|reactome:R-HSA-71403	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+TBWTaRxrIz2Y0dfwkSNf8VZEcw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96BW9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943422|uniprotkb:B4DIY7|uniprotkb:C9J2U4|ensembl:ENSP00000388598	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tam41_human(display_long)|uniprotkb:TAMM41(gene name)|psi-mi:TAMM41(display_short)|uniprotkb:C3orf31(gene name synonym)|uniprotkb:CDP-diacylglycerol synthase(gene name synonym)|uniprotkb:Mitochondrial translocator assembly and maintenance protein 41 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001271330.1|refseq:NP_001308223.1|refseq:NP_001308224.1|refseq:NP_620162.1|refseq:XP_005264930.1|ensembl:ENSG00000144559(gene)|ensembl:ENST00000444133(transcript)|go:"GO:0004605"(phosphatidate cytidylyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016024"(CDP-diacylglycerol biosynthetic process)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032049"(cardiolipin biosynthetic process)|interpro:IPR015222(Mitochondrial matrix Mmp37)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:LnzB9FufQqND2kzBthGVaChZlNw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P23378	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2509907|ensembl:ENSP00000370737|uniprotkb:Q2M2F8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gcsp_human(display_long)|uniprotkb:GLDC(gene name)|psi-mi:GLDC(display_short)|uniprotkb:GCSP(gene name synonym)|uniprotkb:Glycine decarboxylase(gene name synonym)|uniprotkb:Glycine cleavage system P protein(gene name synonym)|uniprotkb:"Glycine dehydrogenase (aminomethyl-transferring)"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000178445(gene)|ensembl:ENST00000321612(transcript)|go:"GO:0004375"("glycine dehydrogenase (decarboxylating) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005960"(glycine cleavage complex)|go:"GO:0006546"(glycine catabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016829"(lyase activity)|go:"GO:0019464"(glycine decarboxylation via glycine cleavage system)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0036255"(response to methylamine)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070280"(pyridoxal binding)|go:"GO:1903442"(response to lipoic acid)|interpro:IPR001597(Aromatic amino acid beta-eliminating lyase/threonine aldolase)|interpro:IPR003437(Glycine cleavage system P-protein)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR020581|rcsb pdb:6I33|rcsb pdb:6I34|rcsb pdb:6I35|reactome:R-HSA-6783984|refseq:NP_000161.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:zNBF42twnLftxt9dEQsTcGD5dts9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NTX5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2807146|uniprotkb:Q5TEG4|uniprotkb:A6NFJ5|uniprotkb:B7Z8S0|uniprotkb:E9PEN7|uniprotkb:E9PR31|uniprotkb:F8W851|uniprotkb:Q5TEF6|uniprotkb:Q5TEF7|uniprotkb:Q5TEG0|uniprotkb:Q9NZ30|uniprotkb:V9HW18|ensembl:ENSP00000436585	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:echd1_human(display_long)|uniprotkb:ECHDC1(gene name)|psi-mi:ECHDC1(display_short)|uniprotkb:Enoyl-CoA hydratase domain-containing protein 1(gene name synonym)|uniprotkb:Methylmalonyl-CoA decarboxylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001002030.1|refseq:NP_001099014.1|refseq:NP_001099015.1|refseq:NP_001132982.1|refseq:NP_060949.2|refseq:XP_016866545.1|refseq:XP_005267104.1|refseq:XP_005267105.1|refseq:XP_005267107.1|ensembl:ENSG00000093144(gene)|ensembl:ENST00000531967(transcript)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016831"(carboxy-lyase activity)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR029045	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:vZu1Sjy6NcNsdjTh0E3CGM0E7Lc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y3Z3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P38435	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10963113|ensembl:ENSP00000233838|uniprotkb:B4DMC5|uniprotkb:E9PEE1|uniprotkb:Q6GU45|uniprotkb:Q14415	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:vkgc_human(display_long)|uniprotkb:GGCX(gene name)|psi-mi:GGCX(display_short)|uniprotkb:GC(gene name synonym)|uniprotkb:Gamma-glutamyl carboxylase(gene name synonym)|uniprotkb:Peptidyl-glutamate 4-carboxylase(gene name synonym)|uniprotkb:Vitamin K gamma glutamyl carboxylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000812.2|refseq:NP_001135741.1|ensembl:ENSG00000115486(gene)|ensembl:ENST00000233838(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0007596"(blood coagulation)|go:"GO:0008488"(gamma-glutamyl carboxylase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017187"(peptidyl-glutamic acid carboxylation)|go:"GO:0019842"(vitamin binding)|interpro:IPR007782(Vitamin K-dependent gamma-carboxylase)|interpro:IPR011020(HTTM)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|mint:P38435|reactome:R-HSA-159740|reactome:R-HSA-9673240	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:icDLv1KyH9HC3h9enCp9S/nXPmM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P11413	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4289891|uniprotkb:Q8IU88|uniprotkb:D3DWX9|uniprotkb:Q16000|uniprotkb:Q16765|uniprotkb:Q8IUA6|uniprotkb:Q8IU70|uniprotkb:Q96PQ2|ensembl:ENSP00000377192|ensembl:ENSP00000377194	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:g6pd_human(display_long)|uniprotkb:G6PD(gene name)|psi-mi:G6PD(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000393.4|refseq:NP_001035810.1|ensembl:ENSG00000160211(gene)|ensembl:ENST00000393562(transcript)|ensembl:ENST00000393564(transcript)|go:"GO:0004345"(glucose-6-phosphate dehydrogenase activity)|go:"GO:0005536"(glucose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006740"(NADPH regeneration)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010041"("response to iron(III) ion")|go:"GO:0010734"(negative regulation of protein glutathionylation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032094"(response to food)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001282(Glucose-6-phosphate dehydrogenase)|interpro:IPR019796|interpro:IPR022674|interpro:IPR022675|interpro:IPR036291|rcsb pdb:1QKI|rcsb pdb:2BH9|rcsb pdb:2BHL|rcsb pdb:5UKW|rcsb pdb:6E07|rcsb pdb:6E08|rcsb pdb:6JYU|rcsb pdb:6VA0|rcsb pdb:6VA7|rcsb pdb:6VA8|rcsb pdb:6VA9|rcsb pdb:6VAQ|reactome:R-HSA-5628897|reactome:R-HSA-71336	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qW8uk6xBGtrxlsosIH6gEG1ZfWA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7L1Q6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1046727|ensembl:ENSP00000386474|intact:EBI-1051097|uniprotkb:Q14281|uniprotkb:Q15394|uniprotkb:Q9BUY0|uniprotkb:B4DLZ8|uniprotkb:B4DWF7|intact:EBI-21351780	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:bzw1_human(display_long)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym)|uniprotkb:Protein Orf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001193996.1|refseq:NP_055485.2|ensembl:ENSG00000082153(gene)|ensembl:ENST00000409600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|mint:Q7L1Q6|refseq:NP_001193997.1|refseq:NP_001193998.1|refseq:NP_001308617.1|refseq:NP_001308619.1|refseq:NP_001308620.1|refseq:NP_001308622.1|refseq:NP_001308623.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4dzFp6AN4tymPA5rHNYlHCCmSaY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P11717	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1048580|uniprotkb:Q7Z7G9|uniprotkb:Q96PT5|ensembl:ENSP00000349437	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mpri_human(display_long)|uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)|uniprotkb:Insulin-like growth factor II receptor(gene name synonym)|uniprotkb:M6P/IGF2 receptor(gene name synonym)|uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym)|uniprotkb:IGF2R(gene name)|psi-mi:IGF2R(display_short)|uniprotkb:MPRI(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000867.2|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|ensembl:ENSG00000197081(gene)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000356956(transcript)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0001889"(liver development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|interpro:IPR044865|mint:P11717|rcsb pdb:1E6F|rcsb pdb:1GP0|rcsb pdb:1GP3|rcsb pdb:1GQB|rcsb pdb:1JPL|rcsb pdb:1JWG|rcsb pdb:1LF8|rcsb pdb:2CNJ|rcsb pdb:2L29|rcsb pdb:2L2A|rcsb pdb:2M68|rcsb pdb:2M6T|rcsb pdb:2V5N|rcsb pdb:2V5O|rcsb pdb:2V5P|rcsb pdb:5IEI|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6P8I|rcsb pdb:6V02|rcsb pdb:6Z30|rcsb pdb:6Z31|rcsb pdb:6Z32|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-6027N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:7lkG6WR8MQ/SONiTV/8g1ZTtKTU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15498	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4402903|uniprotkb:Q53F01|uniprotkb:Q6FGU9|uniprotkb:Q6IB15|uniprotkb:B4DR94|ensembl:ENSP00000223369|ensembl:ENSP00000504623	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ykt6_human(display_long)|uniprotkb:YKT6(gene name)|psi-mi:YKT6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006546.1|refseq:XP_016867171.1|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|rcsb pdb:6J74|rcsb pdb:6J7F|rcsb pdb:6J7X|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9013423|go:"GO:0030659"(cytoplasmic vesicle membrane)|ensembl:ENSG00000106636(gene)|ensembl:ENST00000223369(transcript)|ensembl:ENST00000679020(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030133"(transport vesicle)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:pkTOoQ9XXEVYHKNvqOMCU6x4nZg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q969N2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-726383|uniprotkb:Q2NL69|uniprotkb:Q7Z3N7|uniprotkb:Q9BQY7|uniprotkb:Q9BQY8|uniprotkb:Q9UJG6|uniprotkb:G8JLF5|uniprotkb:Q9Y2Z5|uniprotkb:B7Z3N1|uniprotkb:B7Z7I8|uniprotkb:B2RND5|uniprotkb:E1P622|ensembl:ENSP00000279036	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pigt_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class T protein(gene name synonym)|uniprotkb:PIGT(gene name)|psi-mi:PIGT(display_short)|uniprotkb:CGI-06(orf name)|uniprotkb:PSEC0163(orf name)|uniprotkb:UNQ716/PRO1379(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001171657.1|refseq:NP_001171658.1|refseq:NP_001171659.1|refseq:NP_057021.2|ensembl:ENSG00000124155(gene)|ensembl:ENST00000279036(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|reactome:R-HSA-162791|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042765"(GPI-anchor transamidase complex)|go:"GO:0051402"(neuron apoptotic process)|interpro:IPR007245(Gpi16 subunit, GPI transamidase component)|mint:Q969N2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:i8lWo/nE8QDVR9IA5UpRwpVfPbQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H0U6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2560240|uniprotkb:Q5TAP9|uniprotkb:Q9NZW8|ensembl:ENSP00000356001	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rm18_human(display_long)|uniprotkb:MRPL18(gene name)|psi-mi:MRPL18(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL18m(gene name synonym)|uniprotkb:HSPC071(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_054880.2|ensembl:ENSG00000112110(gene)|ensembl:ENST00000367034(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0035928"(rRNA import into mitochondrion)|interpro:IPR005484(Ribosomal protein L18/L5)|interpro:IPR036967|mint:Q9H0U6|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001305746.1|dip:DIP-56844N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:MtxdrTVdqAfWZqnuxD+PGs218/A9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q05932	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943420|uniprotkb:B3KPW4|uniprotkb:B7Z2Z3|uniprotkb:F5H0K6|uniprotkb:Q5JU19|uniprotkb:Q5JU22|uniprotkb:Q6P2P6|ensembl:ENSP00000362344	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:folc_human(display_long)|uniprotkb:FPGS(gene name)|psi-mi:FPGS(display_short)|uniprotkb:Folylpoly-gamma-glutamate synthetase(gene name synonym)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001018088.1|refseq:NP_001275732.1|refseq:NP_004948.4|ensembl:ENSG00000136877(gene)|ensembl:ENST00000373247(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004326"(tetrahydrofolylpolyglutamate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006760"(folic acid-containing compound metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0046901"(tetrahydrofolylpolyglutamate biosynthetic process)|interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR018109|interpro:IPR023600|interpro:IPR036565|interpro:IPR036615|reactome:R-HSA-196757|go:"GO:0005524"(ATP binding)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:que2wS4pVISUoXjLANzVpLqIXBU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BRK5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1389808|uniprotkb:Q8NBQ3|uniprotkb:Q9NZP7|uniprotkb:B1AME5|uniprotkb:B2RDF1|uniprotkb:B4DSM1|uniprotkb:Q53G52|uniprotkb:Q53HQ9|uniprotkb:Q96AA1|uniprotkb:Q9UN53|intact:EBI-2511482|uniprotkb:B1AME6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cab45_human(display_long)|uniprotkb:Stromal cell-derived factor 4(gene name synonym)|uniprotkb:SDF4(gene name)|psi-mi:SDF4(display_short)|uniprotkb:CAB45(gene name synonym)|uniprotkb:PSEC0034(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057631.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|refseq:XP_011539858.1|interpro:IPR027240|mint:Q9BRK5|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009650"(UV protection)|go:"GO:0016020"(membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0021549"(cerebellum development)|go:"GO:0032059"(bleb)|go:"GO:0042802"(identical protein binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070625"(zymogen granule exocytosis)|go:"GO:0099558"(maintenance of synapse structure)|refseq:NP_057260.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:wQ0Ov1MDf6p0BmUCZRAS+Na/ERc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5XKP0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1053887|uniprotkb:Q86YE5|uniprotkb:A0A0B4J2A5|uniprotkb:K7EKR0|ensembl:ENSP00000309561	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mic13_human(display_long)|uniprotkb:MICOS13(gene name)|psi-mi:MICOS13(display_short)|uniprotkb:C19orf70(gene name synonym)|uniprotkb:MIC13(gene name synonym)|uniprotkb:Protein P117(gene name synonym)|uniprotkb:QIL1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_991330.1|ensembl:ENSG00000174917(gene)|ensembl:ENST00000309324(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0044284"(mitochondrial crista junction)|go:"GO:0061617"(MICOS complex)|go:"GO:0140275"(MIB complex)|interpro:IPR026769|reactome:R-HSA-8949613|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|refseq:NP_001295169.1|refseq:XP_016881737.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:WXuGrcp9zyQSBo/4yW2yQ1uSf/A9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y4B6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|intact:EBI-2559078|intact:EBI-28988191|ensembl:ENSP00000393183|ensembl:ENSP00000506880	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|ensembl:ENST00000335891|ensembl:ENSP00000338857|ensembl:ENSP00000393183|ensembl:ENST00000504652|ensembl:ENSP00000421724|ensembl:ENSP00000506880|ensembl:ENSG00000145041(gene)|ensembl:ENST00000423656(transcript)|ensembl:ENST00000684031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990244"("histone kinase activity (H2A-T120 specific)")|go:"GO:1990245"(histone H2A-T120 phosphorylation)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4P7I|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|dip:DIP-47048N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TC07	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1048247|uniprotkb:B9A6L6|intact:EBI-6190229|uniprotkb:B4DMT9|uniprotkb:J3KNI9|uniprotkb:Q9HA83|intact:EBI-28984447|ensembl:ENSP00000448182	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tbc15_human(display_long)|uniprotkb:TBC1D15(gene name)|psi-mi:TBC1D15(display_short)|uniprotkb:GTPase-activating protein RAB7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001139685.2|refseq:NP_001139686.1|refseq:NP_073608.4|ensembl:ENST00000319106|ensembl:ENSP00000318262|ensembl:ENST00000485960|ensembl:ENSP00000420678|ensembl:ENSP00000448182|ensembl:ENSG00000121749(gene)|ensembl:ENST00000550746(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969|reactome:R-HSA-8854214	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3tlqjLtZ/Bq5H6M00sHIwqNqqw49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15460	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-348033|ensembl:ENSP00000166534|ensembl:ENSP00000368398|ensembl:ENSP00000384999|uniprotkb:Q8WWN0|uniprotkb:D3DQ85|uniprotkb:D3DQ86	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:p4ha2_human(display_long)|uniprotkb:UNQ290/PRO330(orf name)|uniprotkb:P4HA2(gene name)|psi-mi:P4HA2(display_short)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000166534(transcript)|ensembl:ENST00000379104(transcript)|ensembl:ENST00000401867(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0009055"(electron transfer activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|interpro:IPR019734|mint:O15460|rcsb pdb:6EVL|rcsb pdb:6EVM|rcsb pdb:6EVN|rcsb pdb:6EVO|rcsb pdb:6EVP|reactome:R-HSA-1650814|ensembl:ENSG00000072682(gene)|refseq:NP_001136071.1|refseq:NP_004190.1|refseq:NP_001017973.1|refseq:NP_001017974.1|refseq:NP_001136070.1|refseq:XP_016865500.1|refseq:XP_005272173.1|refseq:XP_005272174.1|refseq:XP_005272175.1|refseq:XP_005272176.1|refseq:XP_005272177.1|refseq:XP_006714791.1|refseq:XP_006714792.1|refseq:XP_006714793.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VppOE5KSA6wKWCFN4mCUJsFHDIA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NRG9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3912901|uniprotkb:Q9UG19|uniprotkb:Q9NWI6|uniprotkb:Q5JB47|ensembl:ENSP00000209873	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:aaas_human(display_long)|uniprotkb:AAAS(gene name)|psi-mi:AAAS(display_short)|uniprotkb:ADRACALA(gene name synonym)|uniprotkb:Adracalin(gene name synonym)|uniprotkb:GL003(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001166937.1|refseq:NP_056480.1|ensembl:ENSG00000094914(gene)|ensembl:ENST00000209873(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007612"(learning)|go:"GO:0009566"(fertilization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-8980692|reactome:R-HSA-9609690|reactome:R-HSA-9610379	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fdOcZ59NldwaQJ6nusjn8GAhszo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96JB5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-718818|uniprotkb:Q53FA2|uniprotkb:Q9H3F8|uniprotkb:Q9H8G0|uniprotkb:Q9HBR9|uniprotkb:D3DTU1|uniprotkb:D3DTU2|uniprotkb:B7Z6N4|uniprotkb:F5H3I5|ensembl:ENSP00000344683	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ck5p3_human(display_long)|uniprotkb:CDK5 activator-binding protein C53(gene name synonym)|uniprotkb:Protein HSF-27(gene name synonym)|uniprotkb:CDK5RAP3(gene name)|psi-mi:CDK5RAP3(display_short)|uniprotkb:IC53(gene name synonym)|uniprotkb:MSTP016(orf name)|uniprotkb:OK/SW-cl.114(orf name)|uniprotkb:PP1553(orf name)|uniprotkb:LXXLL/leucine-zipper-containing ARF-binding protein(gene name synonym)|uniprotkb:LZAP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_788276.1|refseq:NP_001265126.1|refseq:XP_011523599.1|refseq:NP_001265127.1|refseq:NP_001265145.1|refseq:NP_001265146.1|ensembl:ENSG00000108465(gene)|ensembl:ENST00000338399(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001889"(liver development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007420"(brain development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010921"(regulation of phosphatase activity)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030262"(apoptotic nuclear changes)|go:"GO:0030332"(cyclin binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0071569"(protein ufmylation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|interpro:IPR008491(Protein of unknown function DUF773)|refseq:XP_016880653.1|refseq:XP_016880654.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:K1S/DQ6fYeOm+MiiGicED0chJAw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N4Q1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2562213|uniprotkb:A8K3Z9|uniprotkb:Q96AI2|uniprotkb:Q96MY6|ensembl:ENSP00000380122	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mia40_human(display_long)|uniprotkb:MIA40(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 4(gene name synonym)|uniprotkb:CHCHD4(gene name)|psi-mi:CHCHD4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001091972.1|refseq:NP_653237.1|ensembl:ENSG00000163528(gene)|ensembl:ENST00000396914(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0051084"('de novo' posttranslational protein folding)|interpro:IPR010625(CHCH)|interpro:IPR039289|mint:Q8N4Q1|rcsb pdb:2K3J|rcsb pdb:2L0Y|reactome:R-HSA-1268020|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|dip:DIP-48483N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ACH8CTQRjTwq7nz6toGTrn3VHlE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:A1L0T0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-720553|uniprotkb:O43341|uniprotkb:Q99651|uniprotkb:Q9BWN5|uniprotkb:Q9UEB2|intact:EBI-3184145|intact:EBI-1236857|uniprotkb:Q96F08|ensembl:ENSP00000263383	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hacl2_human(display_long)|uniprotkb:Acetolactate synthase-like protein(gene name synonym)|uniprotkb:HACL2(gene name synonym)|uniprotkb:ILVBL(gene name)|psi-mi:ILVBL(display_short)|uniprotkb:AHAS(gene name synonym)|uniprotkb:IlvB-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006835.2|refseq:XP_005259774.1|ensembl:ENSG00000105135(gene)|ensembl:ENST00000263383(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001561"(fatty acid alpha-oxidation)|go:"GO:0003984"(acetolactate synthase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005948"(acetolactate synthase complex)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016829"(lyase activity)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR000399(TPP-binding enzymes, conserved site)|interpro:IPR011766(Thiamine pyrophosphate enzyme, C-terminal TPP-binding)|interpro:IPR012000(Thiamine pyrophosphate enzyme, central region)|interpro:IPR012001(Thiamine pyrophosphate enzyme, N-terminal TPP binding region)|interpro:IPR029035|interpro:IPR029061	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:WDj/FsULgscGSIgcTe8+1+vKhS09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P30533	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-715927|uniprotkb:Q2M310|uniprotkb:Q53HQ3|uniprotkb:Q53HS6|uniprotkb:D3DVR9|ensembl:ENSP00000497444	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:amrp_human(display_long)|uniprotkb:Low density lipoprotein receptor-related protein-associated protein 1(gene name synonym)|uniprotkb:LRPAP1(gene name)|psi-mi:LRPAP1(display_short)|uniprotkb:A2MRAP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002328.1|ensembl:ENSG00000163956(gene)|ensembl:ENST00000650182(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0012505"(endomembrane system)|go:"GO:0031904"(endosome lumen)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035473"(lipase binding)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900116"(extracellular negative regulation of signal transduction)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|interpro:IPR009066(Alpha-2-macroglobulin receptor-associated protein, domain 1)|interpro:IPR010483(Alpha-2-macroglobulin RAP, C-terminal)|interpro:IPR036744|interpro:IPR037999|interpro:IPR038001|interpro:IPR038003|mint:P30533|rcsb pdb:1LRE|rcsb pdb:1NRE|rcsb pdb:1OP1|rcsb pdb:1OV2|rcsb pdb:2FCW|rcsb pdb:2FTU|rcsb pdb:2FYL|rcsb pdb:2P01|rcsb pdb:2P03|dip:DIP-39355N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TIbL+P1GW4op4Qawa4lpg8iXUaQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13610	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1050630|uniprotkb:A8K3R6|ensembl:ENSP00000387365|uniprotkb:Q7Z3X9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pwp1_human(display_long)|uniprotkb:Keratinocyte protein IEF SSP 9502(gene name synonym)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_008993.1|refseq:NP_001304892.1|ensembl:ENSG00000136045(gene)|ensembl:ENST00000412830(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q13610	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3LMa4f6IxjpvEoh2Hyu0hHKkY789606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P09001	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5325418|ensembl:ENSP00000264995|uniprotkb:Q6IBT2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rm03_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein uL3m(gene name synonym)|uniprotkb:MRPL3(gene name)|psi-mi:MRPL3(display_short)|uniprotkb:MRL3(gene name synonym)|uniprotkb:RPML3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000114686(gene)|ensembl:ENST00000264995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P09001|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|interpro:IPR019927|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF7|refseq:NP_009139.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:JsDyyXQz9ZMCkRtp5TuL0PGYCjw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92896	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-359610|uniprotkb:Q6P9D1|uniprotkb:Q13221|uniprotkb:D3DUJ7|uniprotkb:B7Z8Y4|ensembl:ENSP00000405984	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gslg1_human(display_long)|uniprotkb:GLG1(gene name)|psi-mi:GLG1(display_short)|uniprotkb:CFR1(gene name synonym)|uniprotkb:ESL1(gene name synonym)|uniprotkb:MG160(gene name synonym)|uniprotkb:Golgi sialoglycoprotein MG-160(gene name synonym)|uniprotkb:E-selectin ligand 1(gene name synonym)|uniprotkb:Cysteine-rich fibroblast growth factor receptor(gene name synonym)|uniprotkb:CFR-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001139138.1|refseq:NP_001139139.1|refseq:NP_036333.2|ensembl:ENSG00000090863(gene)|ensembl:ENST00000422840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0010955"(negative regulation of protein processing)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001893(Cysteine rich repeat)|interpro:IPR017873|interpro:IPR039728|reactome:R-HSA-202733|dip:DIP-27582N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FTlNQD3o/wkPVjXkbB/G73BoBhw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q99797	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3893060|uniprotkb:Q5JV15|uniprotkb:Q5T9Q9|uniprotkb:Q96G65|ensembl:ENSP00000371607	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mipep_human(display_long)|uniprotkb:MIPEP(gene name)|psi-mi:MIPEP(display_short)|uniprotkb:MIP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005923.2|ensembl:ENSG00000027001(gene)|ensembl:ENST00000382172(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006508"(proteolysis)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|interpro:IPR024077|interpro:IPR024079	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:vAXeDaFEEGzQGvsfOQUknrfD74Q9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NBX0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4289902|uniprotkb:Q9Y363|uniprotkb:Q8TAR0|ensembl:ENSP00000355467	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:scpdl_human(display_long)|uniprotkb:SCCPDH(gene name)|psi-mi:SCCPDH(display_short)|uniprotkb:CGI-49(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000143653(gene)|ensembl:ENST00000366510(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030496"(midbody)|go:"GO:0031093"(platelet alpha granule lumen)|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR032095|interpro:IPR036291|reactome:R-HSA-114608|refseq:NP_057086.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3dd8OvU7odCDI/f4Ouk7CJYoxnI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q32P28	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-396328|uniprotkb:Q96SK8|uniprotkb:Q7KZR4|uniprotkb:Q96BR8|uniprotkb:Q96SL5|uniprotkb:Q96SN3|uniprotkb:Q9H6K3|uniprotkb:Q9HC86|uniprotkb:Q9HC87|intact:EBI-2555416|ensembl:ENSP00000296388	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:p3h1_human(display_long)|uniprotkb:P3H1(gene name)|psi-mi:P3H1(display_short)|uniprotkb:GROS1(gene name synonym)|uniprotkb:Growth suppressor 1(gene name synonym)|uniprotkb:LEPRE1(gene name synonym)|uniprotkb:Leucine- and proline-enriched proteoglycan 1(gene name synonym)|uniprotkb:PSEC0109(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001139761.1|refseq:NP_001230175.1|refseq:NP_071751.3|ensembl:ENSG00000117385(gene)|ensembl:ENST00000296388(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0019797"(procollagen-proline 3-dioxygenase activity)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0050821"(protein stabilization)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901874"(negative regulation of post-translational protein modification)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR039575|interpro:IPR039837|mint:Q32P28|reactome:R-HSA-1650814	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:L3euuYyawz69NXv4u6baW/ceVdU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75794	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2808248|ensembl:ENSP00000281141|uniprotkb:Q14107|uniprotkb:Q5T0L9|uniprotkb:Q5T0L4|uniprotkb:Q5T0L7|uniprotkb:Q5T0L8|uniprotkb:A8JZZ7|uniprotkb:Q5T0L5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cd123_human(display_long)|uniprotkb:CDC123(gene name)|psi-mi:CDC123(display_short)|uniprotkb:C10orf7(gene name synonym)|uniprotkb:D123(gene name synonym)|uniprotkb:HT-1080(gene name synonym)|uniprotkb:PZ32(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1905143"(eukaryotic translation initiation factor 2 complex assembly)|interpro:IPR009772(D123)|mint:O75794|go:"GO:0045948"(positive regulation of translational initiation)|ensembl:ENSG00000151465(gene)|ensembl:ENST00000281141(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|refseq:NP_006014.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VMzeYhMYvt77+83yeASAqju49xQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13232	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-713684|uniprotkb:Q9BWH4|ensembl:ENSP00000219302	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndk3_human(display_long)|uniprotkb:Nucleoside diphosphate kinase C(gene name synonym)|uniprotkb:nm23-H3(gene name synonym)|uniprotkb:DR-nm23(gene name synonym)|uniprotkb:NME3(gene name)|psi-mi:NME3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000103024(gene)|ensembl:ENST00000219302(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:Q13232|rcsb pdb:1ZS6|reactome:R-HSA-499943|refseq:NP_002504.2|dip:DIP-49960N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/egrHNJSuCILf6NdwwchG9rUGqI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BSH5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-745201|uniprotkb:B2RD47|ensembl:ENSP00000238379|ensembl:ENSP00000363295	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hdhd3_human(display_long)|uniprotkb:HDHD3(gene name)|psi-mi:HDHD3(display_short)|uniprotkb:C9orf158(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_112496.1|ensembl:ENSG00000119431(gene)|ensembl:ENST00000238379(transcript)|ensembl:ENST00000374180(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR011949(HAD-superfamily hydrolase, subfamily IA, REG-2-like)|interpro:IPR023214|interpro:IPR036412|interpro:IPR041492|rcsb pdb:3K1Z|refseq:NP_001291439.1|refseq:NP_001291440.1|refseq:NP_001291438.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:YX8rSYs8QnEQTmA7uqbY5mrz5nU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P22033	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2690467|uniprotkb:Q9UD64|uniprotkb:Q5SYZ3|uniprotkb:A8K953|uniprotkb:Q96B11|ensembl:ENSP00000274813	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:muta_human(display_long)|uniprotkb:MMUT(gene name)|psi-mi:MMUT(display_short)|uniprotkb:MUT(gene name synonym)|uniprotkb:Methylmalonyl-CoA isomerase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000246.2|refseq:XP_005249200.1|ensembl:ENSG00000146085(gene)|ensembl:ENST00000274813(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0004494"(methylmalonyl-CoA mutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009791"(post-embryonic development)|go:"GO:0031419"(cobalamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0072341"(modified amino acid binding)|interpro:IPR006098(Methylmalonyl-CoA mutase, alpha chain, catalytic)|interpro:IPR006099(Methylmalonyl-CoA mutase, alpha and beta chain, catalytic)|interpro:IPR006158("Cobalamin (vitamin B12)-binding")|interpro:IPR006159(Methylmalonyl-CoA mutase, C-terminal)|interpro:IPR016176("Cobalamin (vitamin B12)-dependent enzyme, catalytic")|interpro:IPR036724|rcsb pdb:2XIJ|rcsb pdb:2XIQ|rcsb pdb:3BIC|reactome:R-HSA-196741|reactome:R-HSA-3359475|reactome:R-HSA-3359478|reactome:R-HSA-71032	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+MH7wKMIxDwO0Nt9736dvyqXr7w9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00116	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2838732|uniprotkb:A5D8U9|uniprotkb:Q2TU35|ensembl:ENSP00000264167	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:adas_human(display_long)|uniprotkb:AGPS(gene name)|psi-mi:AGPS(display_short)|uniprotkb:Aging-associated gene 5 protein(gene name synonym)|uniprotkb:Alkylglycerone-phosphate synthase(gene name synonym)|uniprotkb:AAG5(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003650.1|ensembl:ENSG00000018510(gene)|ensembl:ENST00000264167(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008609"(alkylglycerone-phosphate synthase activity)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR025650|interpro:IPR036318|mint:O00116|reactome:R-HSA-75896|reactome:R-HSA-9033241|reactome:R-HSA-9033500|interpro:IPR016166(FAD-binding, type 2)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:P8f6+j/f+WID0lFZnLIvVN5OSzM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NFQ8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-524567|ensembl:ENSP00000356584|ensembl:ENSP00000477486	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:toip2_human(display_long)|uniprotkb:Lumenal domain-like LAP1(gene name synonym)|uniprotkb:TOR1AIP2(gene name)|psi-mi:TOR1AIP2(display_short)|uniprotkb:LULL1(gene name synonym)|uniprotkb:IFRG15(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_005244996.1|interpro:IPR008662(Lamina-associated polypeptide 1C)|ensembl:ENSG00000169905(gene)|ensembl:ENST00000367612(transcript)|ensembl:ENST00000609928(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|refseq:XP_016855963.1|refseq:XP_016855964.1|refseq:NP_001186189.1|refseq:NP_659471.1|interpro:IPR038599|rcsb pdb:5J1S|rcsb pdb:5J1T	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:HjY3sLjzR1jmKq2EqIKRvY3GxKc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q16850	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2680495|intact:EBI-21358836|uniprotkb:A0A0C4DFL7|uniprotkb:O00770|uniprotkb:Q99868|uniprotkb:Q8N1A8|uniprotkb:O00772|uniprotkb:Q16784|uniprotkb:B2RAI4|uniprotkb:B4DJ55|uniprotkb:A4D1F8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cp51a_human(display_long)|uniprotkb:CYP51(gene name synonym)|uniprotkb:CYPLI(gene name synonym)|uniprotkb:Cytochrome P450 51A1(gene name synonym)|uniprotkb:Cytochrome P450-14DM(gene name synonym)|uniprotkb:Cytochrome P450LI(gene name synonym)|uniprotkb:Sterol 14-alpha demethylase(gene name synonym)|uniprotkb:CYP51A1(gene name)|psi-mi:CYP51A1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	mint:Q16850|refseq:NP_000777.1|refseq:NP_001139624.1|interpro:IPR001128(Cytochrome P450)|interpro:IPR017972|interpro:IPR002403(Cytochrome P450, E-class, group IV)|go:"GO:0008398"(sterol 14-demethylase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0020037"(heme binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|rcsb pdb:3JUS|rcsb pdb:3JUV|rcsb pdb:3LD6|rcsb pdb:4UHI|rcsb pdb:4UHL|rcsb pdb:6Q2T|rcsb pdb:6UEZ|reactome:R-HSA-191273|reactome:R-HSA-211976|reactome:R-HSA-2426168|reactome:R-HSA-9619665|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006694"(steroid biosynthetic process)|interpro:IPR036396	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:yrFu9QoUi7oRnhwLxzbC3e/jhUE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95747	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-620853|intact:EBI-28983016|ensembl:ENSP00000311713|uniprotkb:Q3LR53|uniprotkb:Q7Z501|uniprotkb:Q9UPQ1|intact:EBI-21354189	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:oxsr1_human(display_long)|uniprotkb:Oxidative stress-responsive 1 protein(gene name synonym)|uniprotkb:OXSR1(gene name)|psi-mi:OXSR1(display_short)|uniprotkb:OSR1(gene name synonym)|uniprotkb:KIAA1101(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000172939(gene)|ensembl:ENST00000311806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038116"("chemokine (C-C motif) ligand 21 signaling pathway")|go:"GO:0038146"("chemokine (C-X-C motif) ligand 12 signaling pathway")|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1990869"(cellular response to chemokine)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024678|interpro:IPR028749|mint:O95747|rcsb pdb:2V3S|rcsb pdb:2VWI|rcsb pdb:3DAK|ensembl:ENSP00000311713|refseq:NP_005100.1|dip:DIP-34977N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:B/vq09Ygsvo5paZdMXlX9tyo7aE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UHD9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-947187|uniprotkb:O94798|uniprotkb:Q9H3W6|uniprotkb:Q9HAZ4|uniprotkb:Q5D027|intact:EBI-28967571|ensembl:ENSP00000345195	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ubql2_human(display_long)|uniprotkb:UBQLN2(gene name)|psi-mi:UBQLN2(display_short)|uniprotkb:PLIC2(gene name synonym)|uniprotkb:HRIHFB2157(orf name)|uniprotkb:N4BP4(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 2(gene name synonym)|uniprotkb:Ubiquitin-like product Chap1/Dsk2(gene name synonym)|uniprotkb:DSK2 homolog(gene name synonym)|uniprotkb:Chap1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000345195|refseq:NP_038472.2|dip:DIP-42116N|ensembl:ENSG00000188021(gene)|ensembl:ENST00000338222(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028430|interpro:IPR029071|mint:Q9UHD9|rcsb pdb:1J8C|rcsb pdb:2NBV|rcsb pdb:6MUN|reactome:R-HSA-8856825	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:tElcz7gHFkKFVDTz3PXeNcaBP7U9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P40616	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1052746|uniprotkb:P80417|uniprotkb:Q53XB1|uniprotkb:B4DWW1|ensembl:ENSP00000261636|intact:EBI-11157530	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:arl1_human(display_long)|uniprotkb:ARL1(gene name)|psi-mi:ARL1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001168.1|ensembl:ENSG00000120805(gene)|ensembl:ENST00000261636(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009404"(toxin metabolic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40616|rcsb pdb:1UPT|rcsb pdb:4DCN|rcsb pdb:5EE5|rcsb pdb:5J5C|reactome:R-HSA-6811440|interpro:IPR005225(Small GTP-binding protein)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4sRUSYrH1mt5ol85HlMNSEn1j9M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15479	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1057615|uniprotkb:O75860|ensembl:ENSP00000368273	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:magb2_human(display_long)|uniprotkb:MAGEB2(gene name)|psi-mi:MAGEB2(display_short)|uniprotkb:MAGE-B2 antigen(gene name synonym)|uniprotkb:DSS-AHC critical interval MAGE superfamily 6(gene name synonym)|uniprotkb:MAGE XP-2 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 3.2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011543814.1|refseq:NP_002355.2|ensembl:ENSG00000099399(gene)|ensembl:ENST00000378988(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030084|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:O15479	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:WY4IQcRPAcvf0K4m1G7qDR06slY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N8L6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943418|ensembl:ENSP00000308496	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:arl10_human(display_long)|uniprotkb:ARL10(gene name)|psi-mi:ARL10(display_short)|uniprotkb:ARL10A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000175414(gene)|ensembl:ENST00000310389(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR042951|refseq:NP_775935.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:zAQBnFyjO7dEghDbghsl9o4gfTA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P46199	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-359432|ensembl:ENSP00000263629|ensembl:ENSP00000378099|ensembl:ENSP00000384481|uniprotkb:D6W5D0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:if2m_human(display_long)|uniprotkb:MTIF2(gene name)|psi-mi:MTIF2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001307933.1|refseq:NP_001307934.1|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0070124"(mitochondrial translational initiation)|interpro:IPR000178(Initiation factor 2)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR023115|interpro:IPR027417|interpro:IPR036925|interpro:IPR044145|rcsb pdb:6GAW|rcsb pdb:6GAZ|rcsb pdb:6GB2|rcsb pdb:6RW5|reactome:R-HSA-5368286|ensembl:ENSG00000085760(gene)|ensembl:ENST00000263629(transcript)|ensembl:ENST00000394600(transcript)|ensembl:ENST00000403721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0032790"(ribosome disassembly)|refseq:NP_001005369.1|refseq:NP_002444.2|refseq:XP_011531173.1|refseq:NP_001307930.1|refseq:NP_001307931.1|refseq:NP_001307932.1|refseq:XP_005264392.1|refseq:XP_016859651.1|refseq:XP_016859652.1|dip:DIP-27596N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ThigwWzs0gInoPjmmd8DYvyrWw49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P40763	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N	go:"GO:0043229"(intracellular organelle)	-	crc64:6C00632211C8012D	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95782	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-353552|uniprotkb:Q96CI7|uniprotkb:Q96PP6|uniprotkb:Q96PP7|uniprotkb:Q9H070|intact:EBI-28973302|ensembl:ENSP00000351926	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ap2a1_human(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055018.2|refseq:NP_570603.2|ensembl:ENST00000354293|ensembl:ENSP00000346246|ensembl:ENSP00000351926|ensembl:ENSG00000196961(gene)|ensembl:ENST00000359032(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O95782|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|dip:DIP-33164N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:egkaIAhvIi1FqNr+8KEFeJaYZcc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8IY17	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5453745|uniprotkb:A6NGQ0|uniprotkb:O60859|uniprotkb:Q86W58|uniprotkb:Q9UG58|uniprotkb:B4DFB9|uniprotkb:J3KQS3|uniprotkb:B7Z7T2|uniprotkb:F5H5K9|intact:EBI-28978663|ensembl:ENSP00000407509	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:plpl6_human(display_long)|uniprotkb:PNPLA6(gene name)|psi-mi:PNPLA6(display_short)|uniprotkb:NTE(gene name synonym)|uniprotkb:Neuropathy target esterase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENST00000221249|ensembl:ENSP00000221249|ensembl:ENSP00000407509|ensembl:ENST00000450331|ensembl:ENSP00000394348|ensembl:ENST00000545201|ensembl:ENSP00000443323|refseq:NP_001159583.1|refseq:NP_001159584.1|refseq:NP_001159585.1|refseq:NP_001159586.1|refseq:NP_006693.3|ensembl:ENSG00000032444(gene)|ensembl:ENST00000414982(transcript)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0102545"(phosphatidyl phospholipase B activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR001423(Lysophospholipase patatin, conserved site)|interpro:IPR002641(Patatin)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR018490|mint:Q8IY17|reactome:R-HSA-6814848	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FFCs29b8r1jJ3dKVA6ktEx8jCfo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15270	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-766136|uniprotkb:Q16685|ensembl:ENSP00000216484	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sptc2_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:KIAA0526(gene name synonym)|uniprotkb:LCB2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004854.1|dip:DIP-34604N|ensembl:ENSG00000100596(gene)|ensembl:ENST00000216484(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15270|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BU23	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10298556|uniprotkb:Q96C62|uniprotkb:Q13392|uniprotkb:Q8WU74|uniprotkb:Q6ZNR2|uniprotkb:A6NEZ0|ensembl:ENSP00000424381	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lmf2_human(display_long)|uniprotkb:LMF2(gene name)|psi-mi:LMF2(display_short)|uniprotkb:TMEM112B(gene name synonym)|uniprotkb:TMEM153(gene name synonym)|uniprotkb:Transmembrane protein 112B(gene name synonym)|uniprotkb:Transmembrane protein 153(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_149977.2|refseq:XP_005262012.1|ensembl:ENSG00000100258(gene)|ensembl:ENST00000474879(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051604"(protein maturation)|interpro:IPR009613(Protein of unknown function DUF1222)|reactome:R-HSA-8963889	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xI+AYnn8Oj5BWzpTBzJi4K83wck9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UL15	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96KA5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3216282|ensembl:ENSP00000313854|ensembl:ENSP00000480372|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:clp1l_human(display_long)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000049656(gene)|ensembl:ENSG00000274811(gene)|ensembl:ENST00000320895(transcript)|ensembl:ENST00000620010(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:Q96KA5|refseq:NP_110409.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NF37	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-922595|uniprotkb:Q1HAQ1|uniprotkb:Q7Z4G6|uniprotkb:Q8N3U7|uniprotkb:Q8WUL8|uniprotkb:Q9GZW6|ensembl:ENSP00000283415|ensembl:ENSP00000423472	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pcat1_human(display_long)|uniprotkb:1-alkylglycerophosphocholine O-acetyltransferase(gene name synonym)|uniprotkb:Acyltransferase-like 2(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 3(gene name synonym)|uniprotkb:1-acylglycerol-3-phosphate O-acyltransferase(gene name synonym)|uniprotkb:1-alkenylglycerophosphocholine O-acyltransferase(gene name synonym)|uniprotkb:LPCAT1(gene name)|psi-mi:LPCAT1(display_short)|uniprotkb:AYTL2(gene name synonym)|uniprotkb:PFAAP3(gene name synonym)|uniprotkb:"Acetyl-CoA:lyso-platelet-activating factor acetyltransferase"(gene name synonym)|uniprotkb:1-acylglycerophosphocholine O-acyltransferase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_079106.3|ensembl:ENSG00000153395(gene)|ensembl:ENST00000283415(transcript)|ensembl:ENST00000475622(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0036148"(phosphatidylglycerol acyl-chain remodeling)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047144"(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0047159"(1-alkenylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047191"(1-alkylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047192"(1-alkylglycerophosphocholine O-acetyltransferase activity)|go:"GO:0050200"(plasmalogen synthase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2001246"(negative regulation of phosphatidylcholine biosynthetic process)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR011992(EF-Hand type)|reactome:R-HSA-1482788|reactome:R-HSA-1482925|reactome:R-HSA-1483166|reactome:R-HSA-1483191|reactome:R-HSA-6798695	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:sJPdIAauFmV71N/KwIUH75hTHv09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P25325	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2515082|ensembl:ENSP00000342333|ensembl:ENSP00000380402|ensembl:ENSP00000383950|ensembl:ENSP00000384812|uniprotkb:O75750|uniprotkb:A8MZ34|uniprotkb:B3KP52|uniprotkb:J3KPV7|uniprotkb:Q6FHN9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:thtm_human(display_long)|uniprotkb:MPST(gene name)|psi-mi:MPST(display_short)|uniprotkb:TST2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0070062"(extracellular exosome)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|mint:P25325|rcsb pdb:3OLH|rcsb pdb:4JGT|reactome:R-HSA-1614558|ensembl:ENSG00000128309(gene)|ensembl:ENST00000341116(transcript)|ensembl:ENST00000397225(transcript)|ensembl:ENST00000401419(transcript)|ensembl:ENST00000404802(transcript)|go:"GO:0000098"(sulfur amino acid catabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009440"(cyanate catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016784"(3-mercaptopyruvate sulfurtransferase activity)|go:"GO:0019346"(transsulfuration)|go:"GO:0021510"(spinal cord development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|refseq:NP_001013454.1|refseq:NP_001123989.1|refseq:NP_066949.2|refseq:XP_005261667.1|dip:DIP-613N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:JDsHqxXe71bbWhgF2GcXCOspbpQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y312	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-748721|uniprotkb:Q9H4F9|uniprotkb:Q9P1P3|uniprotkb:Q9UFK9|uniprotkb:E1P5S7|ensembl:ENSP00000313674|ensembl:ENSP00000363043|ensembl:ENSP00000505061|ensembl:ENSP00000505295|ensembl:ENSP00000505405|ensembl:ENSP00000506185|ensembl:ENSP00000506354	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:aar2_human(display_long)|uniprotkb:AAR2(gene name)|psi-mi:AAR2(display_short)|uniprotkb:AAR2 splicing factor homolog(gene name synonym)|uniprotkb:C20orf4(gene name synonym)|uniprotkb:CGI-23(orf name)|uniprotkb:PRO0225(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056326.2|refseq:NP_001258803.1|refseq:XP_006723833.1|refseq:XP_011527065.1|refseq:XP_011527064.1|ensembl:ENSG00000131043(gene)|ensembl:ENST00000320849(transcript)|ensembl:ENST00000373932(transcript)|ensembl:ENST00000679667(transcript)|ensembl:ENST00000680247(transcript)|ensembl:ENST00000680639(transcript)|ensembl:ENST00000680811(transcript)|ensembl:ENST00000680933(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|interpro:IPR007946(AAR2)|interpro:IPR033647|interpro:IPR033648|interpro:IPR038514|interpro:IPR038516|mint:Q9Y312	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:mvbhGa01cuYd3fN8vbbXdzS0mSg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P41240	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1380630|uniprotkb:Q2M3N2|uniprotkb:Q6FGZ6|ensembl:ENSP00000220003|ensembl:ENSP00000414764|ensembl:ENSP00000454906	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:csk_human(display_long)|uniprotkb:CSK(gene name)|psi-mi:CSK(display_short)|uniprotkb:C-Src kinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase CYL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001120662.1|refseq:NP_004374.1|refseq:XP_005254222.1|refseq:XP_016877414.1|ensembl:ENSG00000103653(gene)|ensembl:ENST00000220003(transcript)|ensembl:ENST00000439220(transcript)|ensembl:ENST00000567571(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042997"(negative regulation of Golgi to plasma membrane protein transport)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035027|interpro:IPR036028|interpro:IPR036860|mint:P41240|rcsb pdb:1BYG|rcsb pdb:1CSK|rcsb pdb:3D7T|rcsb pdb:3D7U|rcsb pdb:3EAC|rcsb pdb:3EAZ|reactome:R-HSA-180292|reactome:R-HSA-202427|reactome:R-HSA-354192|reactome:R-HSA-389948|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9013407|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9706369	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9n6rgUUGjJ+e0fMPrB4A7JGyZqE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P11233	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1036803|uniprotkb:A4D1W3|ensembl:ENSP00000005257	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rala_human(display_long)|uniprotkb:RAL(gene name synonym)|uniprotkb:RALA(gene name)|psi-mi:RALA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005393.2|refseq:XP_006715825.1|go:"GO:0019003"(GDP binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031755"(Edg-2 lysophosphatidic acid receptor binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051665"(membrane raft localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090543"(Flemming body)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR028412|rcsb pdb:1UAD|rcsb pdb:1ZC3|rcsb pdb:1ZC4|rcsb pdb:2A78|mint:P11233|rcsb pdb:2A9K|rcsb pdb:2BOV|rcsb pdb:6P0I|rcsb pdb:6P0J|rcsb pdb:6P0K|rcsb pdb:6P0L|rcsb pdb:6P0M|rcsb pdb:6P0N|rcsb pdb:6P0O|reactome:R-HSA-1445148|reactome:R-HSA-171007|reactome:R-HSA-8950505|ensembl:ENSG00000006451(gene)|ensembl:ENST00000005257(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0017022"(myosin binding)|go:"GO:0017157"(regulation of exocytosis)|refseq:XP_011513768.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:41WF1UoYnYZvwC0OPpYwCEqIg2E9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H0U3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2798816|uniprotkb:Q6P577|uniprotkb:B2RAR4|uniprotkb:Q53G00|uniprotkb:Q8NBN6|uniprotkb:D3DTE3|ensembl:ENSP00000354649|ensembl:ENSP00000480732	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:magt1_human(display_long)|uniprotkb:IAG2(gene name synonym)|uniprotkb:Implantation-associated protein(gene name synonym)|uniprotkb:PSEC0084(orf name)|uniprotkb:UNQ628/PRO1244(orf name)|uniprotkb:MAGT1(gene name)|psi-mi:MAGT1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_115497.4|ensembl:ENSG00000102158(gene)|ensembl:ENST00000358075(transcript)|ensembl:ENST00000618282(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0055085"(transmembrane transport)|interpro:IPR006844(OST3/OST6)|interpro:IPR021149|interpro:IPR036249|mint:Q9H0U3|rcsb pdb:6S7T|reactome:R-HSA-446203|reactome:R-HSA-5223345|reactome:R-HSA-6798695|reactome:R-HSA-9694548|go:"GO:0050890"(cognition)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:M7/LTAlkuCCyeqlTlcJkfu2HU9k9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96NB2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6381136|ensembl:ENSP00000358909|uniprotkb:Q5JSM6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sfxn2_human(display_long)|uniprotkb:SFXN2(gene name)|psi-mi:SFXN2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_016871152.1|refseq:XP_011537564.1|ensembl:ENSG00000156398(gene)|ensembl:ENST00000369893(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|refseq:NP_849189.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FNAgN69aAzlfW03f5i/uS+0NSaE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96RQ1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4403663|uniprotkb:A6NHH6|uniprotkb:Q53GY2|uniprotkb:Q8N2Q9|uniprotkb:Q9BVV9|uniprotkb:Q9NZA3|ensembl:ENSP00000353270	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ergi2_human(display_long)|uniprotkb:ERGIC2(gene name)|psi-mi:ERGIC2(display_short)|uniprotkb:ERV41(gene name synonym)|uniprotkb:PTX1(gene name synonym)|uniprotkb:CDA14(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057654.2|ensembl:ENSG00000087502(gene)|ensembl:ENST00000360150(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+T1RODVKNyboKSh3evzH0SZUm7s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96S52	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2908273|uniprotkb:Q6UVX6|ensembl:ENSP00000309430	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pigs_human(display_long)|uniprotkb:PIGS(gene name)|psi-mi:PIGS(display_short)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class S protein(gene name synonym)|uniprotkb:UNQ1873/PRO4316(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000087111(gene)|ensembl:ENST00000308360(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0042765"(GPI-anchor transamidase complex)|interpro:IPR019540|reactome:R-HSA-162791|refseq:NP_149975.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:X+q1ME1DzmszMrPZZ4kjsUrFhGs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13907	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6285983|ensembl:ENSP00000401879|uniprotkb:B4E155|uniprotkb:Q32Q13|uniprotkb:Q53GQ6|uniprotkb:Q86U81|uniprotkb:Q8WUX8|uniprotkb:Q96IZ4|uniprotkb:Q9BQ74	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:idi1_human(display_long)|uniprotkb:IDI1(gene name)|psi-mi:IDI1(display_short)|uniprotkb:Isopentenyl pyrophosphate isomerase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000067064(gene)|ensembl:ENST00000429642(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004452"(isopentenyl-diphosphate delta-isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0009240"(isopentenyl diphosphate biosynthetic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050992"(dimethylallyl diphosphate biosynthetic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR011876(Isopentenyl-diphosphate delta-isomerase, type 1)|interpro:IPR015797(NUDIX)|mint:Q13907|rcsb pdb:2DHO|rcsb pdb:2I6K|rcsb pdb:2ICJ|rcsb pdb:2ICK|reactome:R-HSA-191273|reactome:R-HSA-2426168|refseq:NP_001304884.1|refseq:NP_001304885.1|refseq:NP_001304886.1|refseq:NP_004499.2|refseq:XP_011517759.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:UbjHfBd6yrV1Gxv+R0z56N7DVgA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TCT9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-347472|uniprotkb:Q540H8|uniprotkb:Q5JWP2|uniprotkb:Q5JWP3|uniprotkb:Q5JWP4|uniprotkb:Q5JWP5|uniprotkb:Q7Z4F2|uniprotkb:Q86Y35|uniprotkb:Q95H87|uniprotkb:Q9H110|uniprotkb:Q9H111|uniprotkb:Q15K36|uniprotkb:B2RAY5|uniprotkb:E1P5L3|ensembl:ENSP00000343032	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hm13_human(display_long)|uniprotkb:HM13(gene name)|psi-mi:HM13(display_short)|uniprotkb:H13(gene name synonym)|uniprotkb:PSL3(gene name synonym)|uniprotkb:SPP(gene name synonym)|uniprotkb:Signal peptide peptidase(gene name synonym)|uniprotkb:Presenilin-like protein 3(gene name synonym)|uniprotkb:Intramembrane protease 1(gene name synonym)|uniprotkb:IMP1(gene name synonym)|uniprotkb:MSTP086(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_110416.1|refseq:NP_848695.1|refseq:NP_848696.1|refseq:NP_848697.1|ensembl:ENSG00000101294(gene)|ensembl:ENST00000340852(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042500"(aspartic endopeptidase activity, intramembrane cleaving)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0061960"(regulation of heme oxygenase activity)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:1904211"(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|reactome:R-HSA-9707587	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DxNjJDcc+zomfXAj0TEaByKeNqc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y5V3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14967	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Akb2XoiNjob34njC2erE11yg80w9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UNK9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-12579907|ensembl:ENSP00000251089|uniprotkb:B4DWL7|uniprotkb:O94859|uniprotkb:Q8NCS9	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ange1_human(display_long)|uniprotkb:ANGEL1(gene name)|psi-mi:ANGEL1(display_short)|uniprotkb:KIAA0759(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000013523(gene)|ensembl:ENST00000251089(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|mint:Q9UNK9|refseq:NP_056120.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5WcU0CTNKN6ZYR5zg4oa1LuuAlE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P16278	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-989638|uniprotkb:B7Z6B0|intact:EBI-1018741|uniprotkb:P16279|ensembl:ENSP00000306920|ensembl:ENSP00000382333|uniprotkb:B2R7H8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:bgal_human(display_long)|uniprotkb:ELNR1(gene name synonym)|uniprotkb:Acid beta-galactosidase(gene name synonym)|uniprotkb:Elastin receptor 1(gene name synonym)|uniprotkb:GLB1(gene name)|psi-mi:GLB1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000395.2|refseq:NP_001073279.1|refseq:NP_001129074.1|ensembl:ENSG00000170266(gene)|ensembl:ENST00000399402(transcript)|go:"GO:0004565"(beta-galactosidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006027"(glycosaminoglycan catabolic process)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0016936"(galactoside binding)|go:"GO:0019388"(galactose catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042340"(keratan sulfate catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044262"(cellular carbohydrate metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051413"(response to cortisone)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001944(Glycoside hydrolase, family 35)|interpro:IPR008979(Galactose-binding like)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR019801|interpro:IPR025300|interpro:IPR026283|interpro:IPR031330|mint:P16278|rcsb pdb:3THC|rcsb pdb:3THD|rcsb pdb:3WEZ|rcsb pdb:3WF0|rcsb pdb:3WF1|rcsb pdb:3WF2|rcsb pdb:3WF3|rcsb pdb:3WF4|reactome:R-HSA-1660662|reactome:R-HSA-2022857|reactome:R-HSA-2024096|reactome:R-HSA-2206308|reactome:R-HSA-4085001|ensembl:ENST00000307363(transcript)|reactome:R-HSA-4341670|reactome:R-HSA-6798695|refseq:NP_001303969.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:L/REQ2uBBZimHZnDpo3URvdGTdA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q10469	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943416|ensembl:ENSP00000307423|uniprotkb:B3KPC5|uniprotkb:B3KQM0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mgat2_human(display_long)|uniprotkb:MGAT2(gene name)|psi-mi:MGAT2(display_short)|uniprotkb:Beta-1,2-N-acetylglucosaminyltransferase II(gene name synonym)|uniprotkb:GlcNAc-T II(gene name synonym)|uniprotkb:Mannoside acetylglucosaminyltransferase 2(gene name synonym)|uniprotkb:N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000168282(gene)|ensembl:ENST00000305386(transcript)|go:"GO:0000139"(Golgi membrane)|reactome:R-HSA-975578|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008455"(alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0009312"(oligosaccharide biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0019082"(viral protein processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR007754(N-acetylglucosaminyltransferase II)|interpro:IPR029044|rcsb pdb:5VCM|rcsb pdb:5VCR|rcsb pdb:5VCS|reactome:R-HSA-4793952|reactome:R-HSA-9694548|refseq:NP_002399.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Uua2ZDOZ7QEMwCRDfW/cP2wIG4g9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75131	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-718988|uniprotkb:Q8IYA1|uniprotkb:A8KA47|ensembl:ENSP00000477590	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cpne3_human(display_long)|uniprotkb:Copine III(gene name synonym)|uniprotkb:CPNE3(gene name)|psi-mi:CPNE3(display_short)|uniprotkb:CPN3(gene name synonym)|uniprotkb:KIAA0636(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003900.1|refseq:XP_005251150.1|ensembl:ENSG00000085719(gene)|ensembl:ENST00000517490(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|interpro:IPR035892|interpro:IPR036465|interpro:IPR037768|mint:O75131|reactome:R-HSA-1483206|reactome:R-HSA-6798695|refseq:XP_016869434.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:75lb/sKHpJYCwCLIq973pzNMfzw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NR09	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1765160|uniprotkb:Q9ULD1|ensembl:ENSP00000393596	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:birc6_human(display_long)|uniprotkb:BIRC6(gene name)|psi-mi:BIRC6(display_short)|uniprotkb:KIAA1289(gene name synonym)|uniprotkb:Ubiquitin-conjugating BIR domain enzyme apollon(gene name synonym)|uniprotkb:BIR repeat-containing ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BIRC6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057336.3|ensembl:ENSG00000115760(gene)|ensembl:ENST00000421745(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051301"(cell division)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0060712"(spongiotrophoblast layer development)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0090543"(Flemming body)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR022103|mint:Q9NR09|rcsb pdb:3CEG	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/EZap+9dFkEnO5fRsbzriORwllk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y2I1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2688731|uniprotkb:Q6PIB4|uniprotkb:Q9UEU4|uniprotkb:Q7L8M3|uniprotkb:Q6PGP3|uniprotkb:Q9UFW3|uniprotkb:Q7Z2X6|uniprotkb:Q9UES6|uniprotkb:C9J245|ensembl:ENSP00000339958|ensembl:ENSP00000418232	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nisch_human(display_long)|uniprotkb:IRAS(gene name synonym)|uniprotkb:KIAA0975(gene name synonym)|uniprotkb:Imidazoline receptor 1(gene name synonym)|uniprotkb:Imidazoline receptor antisera-selected protein(gene name synonym)|uniprotkb:Imidazoline-1 receptor(gene name synonym)|uniprotkb:Imidazoline-1 receptor candidate protein(gene name synonym)|uniprotkb:NISCH(gene name)|psi-mi:NISCH(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_009115.2|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048243"(norepinephrine secretion)|go:"GO:0055037"(recycling endosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001683(Phox-like)|interpro:IPR032675|interpro:IPR036871|interpro:IPR037904|mint:Q9Y2I1|rcsb pdb:3P0C|reactome:R-HSA-9013149|reactome:R-HSA-9696264|reactome:R-HSA-9696270|ensembl:ENSG00000010322(gene)|ensembl:ENST00000345716(transcript)|ensembl:ENST00000479054(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|refseq:NP_001263222.1|refseq:NP_001263223.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:GuBgG6MUrD5p1hIhGGmrtCjT0jQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5VV42	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695|ensembl:ENSP00000367873	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060244.2|ensembl:ENSG00000145996(gene)|ensembl:ENST00000274695(transcript)|ensembl:ENST00000378610(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035598"(N6-threonylcarbomyladenosine methylthiotransferase activity)|go:"GO:0035600"(tRNA methylthiolation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P29803	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2957428|ensembl:ENSP00000295266|uniprotkb:Q0VDI5|uniprotkb:Q6NXQ1|uniprotkb:Q4VC02|uniprotkb:B2R9Q3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:odpat_human(display_long)|uniprotkb:PDHA2(gene name)|psi-mi:PDHA2(display_short)|uniprotkb:PDHAL(gene name synonym)|uniprotkb:PDHE1-A type II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000163114(gene)|ensembl:ENST00000295266(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|interpro:IPR029061|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-70268|refseq:NP_005381.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ZJhfjHSJqjS1g4wOVmNTt4+izBE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14548	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-743578|uniprotkb:Q9P118|ensembl:ENSP00000234301|ensembl:ENSP00000367938	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cox7r_human(display_long)|uniprotkb:Cytochrome c oxidase subunit VIIa-related protein(gene name synonym)|uniprotkb:COX7a-related protein(gene name synonym)|uniprotkb:EB1(gene name synonym)|uniprotkb:COX7RP(gene name synonym)|uniprotkb:COX7A2L(gene name)|psi-mi:COX7A2L(display_short)|uniprotkb:COX7AR(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004709.2|refseq:NP_001305965.1|refseq:NP_001305969.1|ensembl:ENSG00000115944(gene)|ensembl:ENST00000234301(transcript)|ensembl:ENST00000378669(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR017267(Cytochrome c oxidase subunit VIIa-related, mitochondrial)|interpro:IPR036539|interpro:IPR039297|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qJHxwSXSwyenuqJmKPhQ3R76aqE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y6N1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2963275|uniprotkb:I3L220|ensembl:ENSP00000299335|ensembl:ENSP00000459901|uniprotkb:Q6FHB7|uniprotkb:Q9BRX0|uniprotkb:Q9UME8|uniprotkb:D3DTY5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cox11_human(display_long)|uniprotkb:COX11(gene name)|psi-mi:COX11(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000166260(gene)|ensembl:ENST00000299335(transcript)|ensembl:ENST00000576370(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009055"(electron transfer activity)|go:"GO:0031304"(intrinsic component of mitochondrial inner membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033132"(negative regulation of glucokinase activity)|go:"GO:0055065"(metal ion homeostasis)|interpro:IPR007533(Cytochrome c oxidase assembly protein CtaG/Cox11)|interpro:IPR023471|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:NP_004366.1|refseq:XP_011522644.1|refseq:XP_016879681.1|refseq:XP_016879682.1|refseq:XP_016879683.1|refseq:XP_016879684.1|refseq:XP_016879685.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:inklcaALt6Jb0Cs/4ckzcG6YrHA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P24311	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2684371|uniprotkb:Q6ICR1|uniprotkb:B2R4M3|ensembl:ENSP00000497474	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cox7b_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide VIIb(gene name synonym)|uniprotkb:COX7B(gene name)|psi-mi:COX7B(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001857.1|ensembl:ENSG00000131174(gene)|ensembl:ENST00000650309(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007417"(central nervous system development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045277"(respiratory chain complex IV)|interpro:IPR008433(Cytochrome C oxidase chain VIIB)|interpro:IPR023272|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:V9AcoXkMThm2bVNnVka9GHOVrfk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P14406	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2606666|uniprotkb:Q5TF59|uniprotkb:Q6FGI2|uniprotkb:Q3MIH5|uniprotkb:B2R5E1|ensembl:ENSP00000506727	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cx7a2_human(display_long)|uniprotkb:COX7AL(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIIa-liver/heart(gene name synonym)|uniprotkb:COX7A2(gene name)|psi-mi:COX7A2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001856.2|ensembl:ENSG00000112695(gene)|ensembl:ENST00000684430(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR036539|interpro:IPR039297|mint:P14406|rcsb pdb:5Z62	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:krjTK658npBV4G6gH28GJhVqBkY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7KZN9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3248549|ensembl:ENSP00000016171|uniprotkb:Q7Z3Q3|uniprotkb:O75878|uniprotkb:Q5TD00|uniprotkb:O60556|uniprotkb:A8K6I9|uniprotkb:Q5TD01|uniprotkb:Q9NTN0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cox15_human(display_long)|uniprotkb:COX15(gene name)|psi-mi:COX15(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000014919(gene)|ensembl:ENST00000016171(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006784"(heme A biosynthetic process)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008535"(respiratory chain complex IV assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0016653"("oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor")|go:"GO:0020037"(heme binding)|go:"GO:0045333"(cellular respiration)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070069"(cytochrome complex)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR003780(Cytochrome oxidase assembly)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR023754|reactome:R-HSA-189451|refseq:NP_004367.2|refseq:NP_510870.1|refseq:NP_001307903.1|refseq:NP_001307904.1|refseq:NP_001307905.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:wdz9gN+Wa6J/2OWm1flGDTmR7vM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96TC7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1056589|uniprotkb:A9UMZ9|uniprotkb:Q6ZWE9|uniprotkb:Q96H23|uniprotkb:Q96SD6|uniprotkb:Q9H6G1|uniprotkb:Q9NVQ6|uniprotkb:B3KRR3|intact:EBI-2563869|ensembl:ENSP00000260385|ensembl:ENSP00000342493	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rmd3_human(display_long)|uniprotkb:Protein tyrosine phosphatase-interacting protein 51(gene name synonym)|uniprotkb:TCPTP-interacting protein 51(gene name synonym)|uniprotkb:UNQ3122/PRO10274(orf name)|uniprotkb:hucep-10(orf name)|uniprotkb:RMDN3(gene name)|psi-mi:RMDN3(display_short)|uniprotkb:Cerebral protein 10(gene name synonym)|uniprotkb:FAM82A2(gene name synonym)|uniprotkb:FAM82C(gene name synonym)|uniprotkb:PTPIP51(gene name synonym)|uniprotkb:Protein FAM82A2(gene name synonym)|uniprotkb:Protein FAM82C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060615.1|refseq:NP_001310823.1|refseq:NP_001310824.1|refseq:NP_001291731.1|ensembl:ENSG00000137824(gene)|ensembl:ENST00000260385(transcript)|ensembl:ENST00000338376(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045171"(intercellular bridge)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:7CC7	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+y9NPJiIL0BOpjWINH8zcfp5b9o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9P2K2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UPY3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-395506|uniprotkb:O95943|uniprotkb:Q9UQ02|uniprotkb:A7E2D3|ensembl:ENSP00000343745|ensembl:ENSP00000376783|ensembl:ENSP00000435681|ensembl:ENSP00000437256|uniprotkb:E0AD28|uniprotkb:B3KRG4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dicer_human(display_long)|uniprotkb:DICER1(gene name)|psi-mi:DICER1(display_short)|uniprotkb:DICER(gene name synonym)|uniprotkb:HERNA(gene name synonym)|uniprotkb:KIAA0928(gene name synonym)|uniprotkb:Helicase with RNase motif(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_085124.2|refseq:NP_803187.1|refseq:NP_001182502.1|refseq:XP_011534901.1|refseq:XP_011534902.1|refseq:XP_011534903.1|refseq:XP_011534904.1|ensembl:ENSG00000100697(gene)|ensembl:ENST00000343455(transcript)|ensembl:ENST00000393063(transcript)|ensembl:ENST00000526495(transcript)|ensembl:ENST00000527414(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021675"(nerve development)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032290"(peripheral nervous system myelin formation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033167"(ARC complex)|go:"GO:0033168"(obsolete conversion of ds siRNA to ss siRNA involved in RNA interference)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0036404"(obsolete conversion of ds siRNA to ss siRNA)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:0090501"(RNA phosphodiester bond hydrolysis)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR000999(Ribonuclease III)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR005034(Protein of unknown function DUF283)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR036085|interpro:IPR036389|interpro:IPR038248|interpro:IPR044441|mint:Q9UPY3|rcsb pdb:2EB1|rcsb pdb:4NGB|rcsb pdb:4NGC|rcsb pdb:4NGD|rcsb pdb:4NGF|rcsb pdb:4NGG|rcsb pdb:4NH3|rcsb pdb:4NH5|rcsb pdb:4NH6|rcsb pdb:4NHA|rcsb pdb:4WYQ|rcsb pdb:5ZAK|rcsb pdb:5ZAL|rcsb pdb:5ZAM|reactome:R-HSA-203927|reactome:R-HSA-426486|go:"GO:0035280"(miRNA loading onto RISC)|reactome:R-HSA-9708296|refseq:NP_001258211.1|refseq:NP_001278557.1|refseq:XP_016876609.1|refseq:XP_016876610.1|dip:DIP-29664N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RhSXQEEvS9b0IOvnrPYhRd0MzI09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13586	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5JTV8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2559665|uniprotkb:Q9H8Y6|uniprotkb:Q8IZ65|uniprotkb:Q5JTV6|uniprotkb:B0QZ57|uniprotkb:Q9Y3X5|uniprotkb:Q9HAJ1|uniprotkb:Q9NV52|uniprotkb:A8K630|ensembl:ENSP00000476687	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:toip1_human(display_long)|uniprotkb:TOR1AIP1(gene name)|psi-mi:TOR1AIP1(display_short)|uniprotkb:Lamin-associated protein 1B(gene name synonym)|uniprotkb:LAP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056417.2|ensembl:ENSG00000143337(gene)|ensembl:ENST00000606911(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0051117"(ATPase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR008662(Lamina-associated polypeptide 1C)|interpro:IPR038599|rcsb pdb:4TVS|reactome:R-HSA-9013405|reactome:R-HSA-9035034|refseq:NP_001254507.1|dip:DIP-56692N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qFH5HTm3fcIwmGL486H8IqZHG489606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BYT8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4407509|uniprotkb:Q9ULJ4|ensembl:ENSP00000370372	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:neul_human(display_long)|uniprotkb:NLN(gene name)|psi-mi:NLN(display_short)|uniprotkb:AGTBP(gene name synonym)|uniprotkb:KIAA1226(gene name synonym)|uniprotkb:Angiotensin-binding protein(gene name synonym)|uniprotkb:Microsomal endopeptidase(gene name synonym)|uniprotkb:Mitochondrial oligopeptidase M(gene name synonym)|uniprotkb:Neurotensin endopeptidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_065777.1|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006508"(proteolysis)|go:"GO:0006518"(peptide metabolic process)|ensembl:ENSG00000123213(gene)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1902809"(regulation of skeletal muscle fiber differentiation)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|interpro:IPR024077|interpro:IPR024079|interpro:IPR024080|rcsb pdb:5LUZ|rcsb pdb:5LV0|reactome:R-HSA-375276|ensembl:ENST00000380985(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:d4G0vzunM/wqUiwHOFIdsyX12ZE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q3SY69	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6916128|ensembl:ENSP00000258494|uniprotkb:Q3SY68|uniprotkb:Q68D62|uniprotkb:Q6AI55|uniprotkb:Q8N922	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:al1l2_human(display_long)|uniprotkb:ALDH1L2(gene name)|psi-mi:ALDH1L2(display_short)|uniprotkb:Aldehyde dehydrogenase family 1 member L2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011536291.1|ensembl:ENST00000258494(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009258"(10-formyltetrahydrofolate catabolic process)|go:"GO:0016155"(formyltetrahydrofolate dehydrogenase activity)|go:"GO:0016742"(hydroxymethyl-, formyl- and related transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR011407(10-formyltetrahydrofolate dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|ensembl:ENSG00000136010(gene)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|interpro:IPR036477|interpro:IPR036736|interpro:IPR037022|mint:Q3SY69|reactome:R-HSA-196757|refseq:NP_001029345.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Tfg9TJwXfyRvVxezABcOGaJrcas9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P26440	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2866408|uniprotkb:J3KR54|uniprotkb:Q53XZ9|uniprotkb:Q96AF6|uniprotkb:B2RCV5|uniprotkb:B3KVI7|ensembl:ENSP00000499074	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ivd_human(display_long)|uniprotkb:IVD(gene name)|psi-mi:IVD(display_short)|uniprotkb:Butyryl-CoA dehydrogenase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002216.2|refseq:NP_001152980.1|ensembl:ENSG00000128928(gene)|ensembl:ENST00000651168(transcript)|go:"GO:0004085"(butyryl-CoA dehydrogenase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0008470"(isovaleryl-CoA dehydrogenase activity)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042802"(identical protein binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034183|interpro:IPR036250|interpro:IPR037069|rcsb pdb:1IVH|reactome:R-HSA-70895	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:GewB1Yyc2EEVepN5e1H068xpjI09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8N766	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NUQ7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11153325|uniprotkb:Q96FS3|uniprotkb:Q6IA77|ensembl:ENSP00000264689	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ufsp2_human(display_long)|uniprotkb:UFSP2(gene name)|psi-mi:UFSP2(display_short)|uniprotkb:C4orf20(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060829.2|ensembl:ENSG00000109775(gene)|ensembl:ENST00000264689(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006508"(proteolysis)|go:"GO:0016790"(thiolester hydrolase activity)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0071567"(UFM1 hydrolase activity)|interpro:IPR012462(Peptidase C78, ubiquitin fold modifier-specific peptidase 1 and 2)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:oRkT3OCCM2J2sJXS/z79bkeKh+49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H3G5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:antgab61u6D+KmbopQeowXqSqWQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15645	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358993|uniprotkb:C9K0T3|uniprotkb:O15324|ensembl:ENSP00000166345|uniprotkb:D3DTC0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pch2_human(display_long)|uniprotkb:TRIP13(gene name)|psi-mi:TRIP13(display_short)|uniprotkb:Thyroid receptor-interacting protein 13(gene name synonym)|uniprotkb:PCH2(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 13(gene name synonym)|uniprotkb:Human papillomavirus type 16 E1 protein-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004228.1|ensembl:ENSG00000071539(gene)|ensembl:ENST00000166345(transcript)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_011512465.1|dip:DIP-34493N|go:"GO:0005694"(chromosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0042802"(identical protein binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|interpro:IPR044539|mint:Q15645|rcsb pdb:5VQ9|rcsb pdb:5VQA|rcsb pdb:5WC2|rcsb pdb:6F0X|rcsb pdb:6LK0|rcsb pdb:7L9P	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:heF2f3R2lGIpZ80mZHnhMktXTE49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y679	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P42126	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3916545|uniprotkb:Q9UDG6|uniprotkb:Q7Z2L6|uniprotkb:Q9BUB8|uniprotkb:Q7Z2L7|uniprotkb:A8K512|uniprotkb:Q13290|uniprotkb:Q9BW05|ensembl:ENSP00000301729	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:eci1_human(display_long)|uniprotkb:ECI1(gene name)|psi-mi:ECI1(display_short)|uniprotkb:DCI(gene name synonym)|uniprotkb:3,2-trans-enoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),Delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001171500.1|refseq:NP_001910.2|ensembl:ENSG00000167969(gene)|ensembl:ENST00000301729(transcript)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|mint:P42126|rcsb pdb:1SG4|reactome:R-HSA-77288|interpro:IPR029045	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:2243TLwuS1/H1h7qBk/lL0DFQGI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6ZRP7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11127401|uniprotkb:Q7Z7B6|uniprotkb:Q8N3G2|uniprotkb:A6NLB0|uniprotkb:Q86VV7|uniprotkb:Q5TB37|uniprotkb:A2CEE0|ensembl:ENSP00000351536	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:qsox2_human(display_long)|uniprotkb:QSOX2(gene name)|psi-mi:QSOX2(display_short)|uniprotkb:Neuroblastoma-derived sulfhydryl oxidase(gene name synonym)|uniprotkb:QSCN6L1(gene name synonym)|uniprotkb:Quiescin Q6-like protein 1(gene name synonym)|uniprotkb:SOXN(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_859052.3|ensembl:ENSG00000165661(gene)|ensembl:ENST00000358701(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017905|interpro:IPR036249|interpro:IPR036774|interpro:IPR039798|interpro:IPR040986|interpro:IPR041269|interpro:IPR042568	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:P58P7yZCL+dIpUXwETr5Ppt/SQw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UBB4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-702390|uniprotkb:O14998|uniprotkb:O15009|uniprotkb:Q6I9X4|uniprotkb:A6NLC4|uniprotkb:B4DG05|ensembl:ENSP00000252934	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:atx10_human(display_long)|uniprotkb:Spinocerebellar ataxia type 10 protein(gene name synonym)|uniprotkb:Brain protein E46 homolog(gene name synonym)|uniprotkb:ATXN10(gene name)|psi-mi:ATXN10(display_short)|uniprotkb:SCA10(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001161093.1|refseq:NP_037368.1|ensembl:ENSG00000130638(gene)|ensembl:ENST00000252934(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:Q9UBB4	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:kQ+1aM5ZEzIlpH2lKWFGVSrCDww9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UH62	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-717832|uniprotkb:Q53HC6|uniprotkb:Q7LCF5|uniprotkb:Q9NPE4|ensembl:ENSP00000340672|ensembl:ENSP00000439032|ensembl:ENSP00000454483	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:armx3_human(display_long)|uniprotkb:ARM protein lost in epithelial cancers on chromosome X 3(gene name synonym)|uniprotkb:ARMCX3(gene name)|psi-mi:ARMCX3(display_short)|uniprotkb:ALEX3(gene name synonym)|uniprotkb:BM-017(orf name)|uniprotkb:UNQ2517/PRO6007(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057691.1|refseq:NP_808816.1|refseq:NP_808817.1|refseq:XP_005262198.1|ensembl:ENSG00000102401(gene)|ensembl:ENST00000341189(transcript)|ensembl:ENST00000471229(transcript)|ensembl:ENST00000537169(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000225(Armadillo)|interpro:IPR006911(Protein of unknown function DUF634)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|reactome:R-HSA-9013404	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Svmu819cxCJThLvYapRMLQpAszw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z4H7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2558196|uniprotkb:Q05CG1|uniprotkb:Q14CB6|uniprotkb:Q2TA91|uniprotkb:Q8IZQ4|uniprotkb:Q9H998|uniprotkb:Q96FN0|uniprotkb:Q14CD9|uniprotkb:B3KPK4|uniprotkb:Q6IQ10|uniprotkb:Q9H950|uniprotkb:Q9NXT8|uniprotkb:Q9HCJ8|uniprotkb:Q6NZX5|uniprotkb:B4DX82|ensembl:ENSP00000369871	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:haus6_human(display_long)|uniprotkb:HAUS6(gene name)|psi-mi:HAUS6(display_short)|uniprotkb:DGT6(gene name synonym)|uniprotkb:FAM29A(gene name synonym)|uniprotkb:KIAA1574(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060115.3|refseq:NP_001257819.1|dip:DIP-48830N|ensembl:ENSG00000147874(gene)|ensembl:ENST00000380502(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026797|interpro:IPR028163|mint:Q7Z4H7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:l5edu15aLS4hXrPg/lfQ2323G2o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13438	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q14165	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1046466|ensembl:ENSP00000228506	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mlec_human(display_long)|uniprotkb:MLEC(gene name)|psi-mi:MLEC(display_short)|uniprotkb:KIAA0152(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000110917(gene)|ensembl:ENST00000228506(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0035579"(specific granule membrane)|interpro:IPR021720|interpro:IPR039155|rcsb pdb:6S7T|reactome:R-HSA-532668|reactome:R-HSA-6798695|refseq:NP_055545.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bEjayZ3by/oF+uvxqdw2r69ab2k9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y2W6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P68036	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q12797	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2967294|ensembl:ENSP00000368767|uniprotkb:B4E2K4|uniprotkb:F5H667|uniprotkb:Q9NRI0|uniprotkb:Q9Y4J0|uniprotkb:Q9H2C4|uniprotkb:A6NDF4|uniprotkb:Q9NRI1|uniprotkb:A6NHI2|uniprotkb:B4DIC9|uniprotkb:B7ZM95|uniprotkb:E5RGP5|uniprotkb:Q6NXR7|uniprotkb:Q8TB28|uniprotkb:Q9H291|intact:EBI-8994140|uniprotkb:A0A0A0MSK8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:asph_human(display_long)|uniprotkb:ASPH(gene name)|psi-mi:ASPH(display_short)|uniprotkb:Aspartate beta-hydroxylase(gene name synonym)|uniprotkb:Peptide-aspartate beta-dioxygenase(gene name synonym)|uniprotkb:BAH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000198363(gene)|ensembl:ENST00000379454(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009055"(electron transfer activity)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033198"(response to ATP)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0062101"(peptidyl-aspartic acid 3-dioxygenase activity)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR007803(Aspartyl/Asparaginyl beta-hydroxylase)|interpro:IPR007943(Aspartyl beta-hydroxylase, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:5APA|rcsb pdb:5JQY|interpro:IPR019734|rcsb pdb:5JTC|interpro:IPR027443|interpro:IPR039038|rcsb pdb:5JZ6|mint:Q12797|rcsb pdb:5JZ8|rcsb pdb:5JZA|rcsb pdb:5JZU|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6QA5|rcsb pdb:6RK9|rcsb pdb:6YYU|rcsb pdb:6YYV|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|reactome:R-HSA-5578775|reactome:R-HSA-2672351|refseq:NP_001158222.1|refseq:NP_004309.2|refseq:NP_064549.1|refseq:NP_115855.1|refseq:NP_115856.1|refseq:NP_001158223.1|refseq:NP_001158225.1|refseq:NP_001158227.1|refseq:NP_001158228.1|refseq:NP_115857.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8Sv1CuwqdVCK6/PF6kL0hkX3/tw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q70CQ3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2512374|ensembl:ENSP00000257548|uniprotkb:Q9BSS3|uniprotkb:Q96JX4|uniprotkb:Q8WTU7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ubp30_human(display_long)|uniprotkb:USP30(gene name)|psi-mi:USP30(display_short)|uniprotkb:Ubiquitin-specific-processing protease 30(gene name synonym)|uniprotkb:Deubiquitinating enzyme 30(gene name synonym)|uniprotkb:Ubiquitin thioesterase 30(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000135093(gene)|ensembl:ENST00000257548(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000425"(pexophagy)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0044313"(protein K6-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901525"(negative regulation of mitophagy)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|rcsb pdb:5OHK|rcsb pdb:5OHN|rcsb pdb:5OHP|reactome:R-HSA-5689880|reactome:R-HSA-9664873|refseq:NP_001288104.1|refseq:NP_116052.2|refseq:XP_006719716.1|dip:DIP-53578N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:KWb+QBK14roR0XS+MQNdf60cO4w9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6P4A7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1049439|uniprotkb:Q6WSU4|uniprotkb:Q86TD9|ensembl:ENSP00000347924	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sfxn4_human(display_long)|uniprotkb:Breast cancer resistance marker 1(gene name synonym)|uniprotkb:SFXN4(gene name)|psi-mi:SFXN4(display_short)|uniprotkb:BCRM1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_998814.1|refseq:XP_011537584.1|refseq:XP_005269583.1|refseq:XP_005269584.1|ensembl:ENSG00000183605(gene)|ensembl:ENST00000355697(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006865"(amino acid transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|interpro:IPR028825	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:D/Ae1Kd5aIiliqNVmS7aFaIpwsk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P05556	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q12907	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3915406|uniprotkb:Q53HH1|ensembl:ENSP00000303366	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lman2_human(display_long)|uniprotkb:LMAN2(gene name)|psi-mi:LMAN2(display_short)|uniprotkb:C5orf8(gene name synonym)|uniprotkb:Glycoprotein GP36b(gene name synonym)|uniprotkb:Lectin mannose-binding 2(gene name synonym)|uniprotkb:Vesicular integral-membrane protein 36(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006807.1|ensembl:ENSG00000169223(gene)|ensembl:ENST00000303127(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035664|mint:Q12907|reactome:R-HSA-204005|reactome:R-HSA-5694530	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:goqUZGW9/lvVMWDAZS9csH3TqWY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6DKK2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-948354|ensembl:ENSP00000261647|uniprotkb:Q7L3U8|uniprotkb:Q9NXB2|uniprotkb:A8MZ52|uniprotkb:B3KP62|uniprotkb:B4DN65|uniprotkb:Q9H6G3|uniprotkb:Q2M248	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ttc19_human(display_long)|uniprotkb:TTC19(gene name)|psi-mi:TTC19(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000011295(gene)|ensembl:ENST00000261647(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005813"(centrosome)|go:"GO:0030496"(midbody)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0070469"(respirasome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040395|mint:Q6DKK2|refseq:NP_001258349.1|refseq:NP_060245.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:skTQJ+iUoHBb06IqVhoprLMYEtA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92820	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3045534|ensembl:ENSP00000260118	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000137563(gene)|ensembl:ENST00000260118(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0034722"(gamma-glutamyl-peptidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0046900"(tetrahydrofolylpolyglutamate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070500"(poly-gamma-glutamate metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|rcsb pdb:1L9X|reactome:R-HSA-6798695|refseq:NP_003869.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NTJ5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3917235|uniprotkb:B4DK71|uniprotkb:Q7LA14|uniprotkb:A8K527|uniprotkb:Q96AX7|uniprotkb:Q9NQ46|uniprotkb:Q9NQ57|uniprotkb:O94935|uniprotkb:Q7LA22|ensembl:ENSP00000373713|ensembl:ENSP00000500361	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sac1_human(display_long)|uniprotkb:SACM1L(gene name)|psi-mi:SACM1L(display_short)|uniprotkb:KIAA0851(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)|uniprotkb:SAC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:XP_011531802.1|refseq:NP_054735.3|refseq:NP_001306001.1|refseq:NP_001306002.1|ensembl:ENSG00000211456(gene)|ensembl:ENST00000389061(transcript)|ensembl:ENST00000672477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034593"(phosphatidylinositol bisphosphate phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|reactome:R-HSA-1483248|reactome:R-HSA-1660514|go:"GO:0016791"(phosphatase activity)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:aaI+D/4SJcwZxWqoxDJ81dA60nU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92538	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-359050|uniprotkb:Q5VXX3|uniprotkb:Q96CK6|uniprotkb:Q96HZ3|uniprotkb:Q9H473|uniprotkb:Q149P0|uniprotkb:Q149P1|ensembl:ENSP00000503207|ensembl:ENSP00000503981	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gbf1_human(display_long)|uniprotkb:GBF1(gene name)|psi-mi:GBF1(display_short)|uniprotkb:KIAA0248(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186307.1|refseq:NP_001186308.1|refseq:NP_004184.1|ensembl:ENSP00000503207|ensembl:ENSP00000503981|ensembl:ENST00000676993|ensembl:ENSP00000503918|ensembl:ENST00000677240|ensembl:ENSP00000503428|ensembl:ENSG00000107862(gene)|ensembl:ENST00000676513(transcript)|ensembl:ENST00000676939(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002263"(cell activation involved in immune response)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0060271"(cilium assembly)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097111"(endoplasmic reticulum-Golgi intermediate compartment organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|go:"GO:1903420"(protein localization to endoplasmic reticulum tubular network)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR000904(SEC7-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023394|interpro:IPR032691|interpro:IPR035999|mint:Q92538|reactome:R-HSA-199992|reactome:R-HSA-5620916|reactome:R-HSA-6807878|reactome:R-HSA-6811434	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4rA/2NVw35m+b6O7/+9noI3EO4o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5W0B1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2562035|uniprotkb:Q9H8M0|uniprotkb:B2RN99|uniprotkb:Q9H0T2|uniprotkb:Q8TBY2|ensembl:ENSP00000282003	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:obi1_human(display_long)|uniprotkb:OBI1(gene name)|psi-mi:OBI1(display_short)|uniprotkb:C13orf7(gene name synonym)|uniprotkb:RING finger protein 219(gene name synonym)|uniprotkb:RNF219(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_078822.3|ensembl:ENSG00000152193(gene)|ensembl:ENST00000282003(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR035691|interpro:IPR039209|mint:Q5W0B1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:MCzyMLZ+OMynQerFlsiwIHPRc0M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92791	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943414|ensembl:ENSP00000347649|ensembl:ENSP00000377505|uniprotkb:Q53GI6|uniprotkb:Q9H4F6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sc65_human(display_long)|uniprotkb:P3H4(gene name)|psi-mi:P3H4(display_short)|uniprotkb:LEPREL4(gene name synonym)|uniprotkb:Leprecan-like protein 4(gene name synonym)|uniprotkb:NOL55(gene name synonym)|uniprotkb:Nucleolar autoantigen No55(gene name synonym)|uniprotkb:Prolyl 3-hydroxylase family member 4(gene name synonym)|uniprotkb:SC65(gene name synonym)|uniprotkb:Synaptonemal complex protein SC65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000141696(gene)|ensembl:ENST00000355468(transcript)|ensembl:ENST00000393928(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0017185"(peptidyl-lysine hydroxylation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046849"(bone remodeling)|go:"GO:1902494"(catalytic complex)|interpro:IPR033213|refseq:NP_006446.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:i20O7LYwB0++JeRbgMw/v8Af/gM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P18031	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-968788|ensembl:ENSP00000360683|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000196396(gene)|ensembl:ENST00000371621(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097443"(sorting endosome)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1AAX|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2NT7|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2NTA|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2QBP|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2QBS|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2VEU|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2F6Z|rcsb pdb:2ZMM|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:6OMY|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:3EB1|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:7KEN|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MM1|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|rcsb pdb:6PFW|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QDV|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P42224	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BPW8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-307125|uniprotkb:O43800|uniprotkb:B2RAY3|ensembl:ENSP00000216121	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nips1_human(display_long)|uniprotkb:NIPSNAP1(gene name)|psi-mi:NIPSNAP1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001189431.1|refseq:NP_003625.2|ensembl:ENSG00000184117(gene)|ensembl:ENST00000216121(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:Q9BPW8	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:mOosuRNhEeYvVB5cUbkMzTJ7X7s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P30044	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-722161|uniprotkb:Q14CK0|uniprotkb:Q6IAF2|uniprotkb:Q9UBU5|uniprotkb:Q9UJU4|uniprotkb:Q9UKX4|uniprotkb:A6NG06|uniprotkb:B7ZLJ4|uniprotkb:A6NC19|uniprotkb:B7ZVW3|ensembl:ENSP00000265462	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:prdx5_human(display_long)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:TPx type VI(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 71B(gene name synonym)|uniprotkb:Alu corepressor 1(gene name synonym)|uniprotkb:PRDX5(gene name)|psi-mi:PRDX5(display_short)|uniprotkb:ACR1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)|uniprotkb:SBBI10(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_036226.1|refseq:NP_857634.1|refseq:NP_857635.1|ensembl:ENSG00000126432(gene)|ensembl:ENST00000265462(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037944|mint:P30044|rcsb pdb:1H4O|rcsb pdb:1HD2|rcsb pdb:1OC3|rcsb pdb:1URM|rcsb pdb:2VL2|rcsb pdb:2VL3|rcsb pdb:2VL9|rcsb pdb:3MNG|rcsb pdb:4K7I|rcsb pdb:4K7N|rcsb pdb:4K7O|rcsb pdb:4MMM|reactome:R-HSA-3299685|reactome:R-HSA-5628897	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Z1fs04RUXWI7z+s7Y+hzGige4mU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UH99	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P82909	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11020727|uniprotkb:Q9H2H4|ensembl:ENSP00000256441|ensembl:ENSP00000482331	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rt36_human(display_long)|uniprotkb:MRPS36(gene name)|psi-mi:MRPS36(display_short)|uniprotkb:Alpha-ketoglutarate dehydrogenase component 4(gene name synonym)|uniprotkb:KGD4(gene name synonym)|uniprotkb:DC47(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_150597.1|ensembl:ENSG00000134056(gene)|ensembl:ENSG00000278461(gene)|ensembl:ENST00000256441(transcript)|ensembl:ENST00000613100(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006412"(translation)|go:"GO:0009353"(mitochondrial oxoglutarate dehydrogenase complex)|interpro:IPR020373|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:7oEY4QJNE/NCNZXlaqXftm4yTIc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q06210	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1055540|uniprotkb:Q9BXF8|uniprotkb:Q53QE6|ensembl:ENSP00000349860	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gfpt1_human(display_long)|uniprotkb:D-fructose-6-phosphate amidotransferase 1(gene name synonym)|uniprotkb:Hexosephosphate aminotransferase 1(gene name synonym)|uniprotkb:GFPT1(gene name)|psi-mi:GFPT1(display_short)|uniprotkb:GFAT(gene name synonym)|uniprotkb:GFPT(gene name synonym)|uniprotkb:"Glutamine:fructose-6-phosphate amidotransferase 1"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002047.2|refseq:NP_001231639.1|ensembl:ENSG00000198380(gene)|ensembl:ENST00000357308(transcript)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490|mint:Q06210|rcsb pdb:2V4M|rcsb pdb:2ZJ3|rcsb pdb:2ZJ4|rcsb pdb:6R4E|rcsb pdb:6R4F|rcsb pdb:6R4G|rcsb pdb:6R4H|rcsb pdb:6R4I|rcsb pdb:6R4J|rcsb pdb:6SVM|rcsb pdb:6SVO|rcsb pdb:6SVP|rcsb pdb:6SVQ|rcsb pdb:6ZMJ|rcsb pdb:6ZMK|rcsb pdb:7NDL|reactome:R-HSA-381038|reactome:R-HSA-4085023|reactome:R-HSA-446210	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fP9V7Qv/Wv8EaxMa0lrY4icjCno9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8IYQ7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2515422|ensembl:ENSP00000365534|ensembl:ENSP00000434887|uniprotkb:Q5VV21|uniprotkb:B3KWL1|uniprotkb:D3DRV3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:thns1_human(display_long)|uniprotkb:THNSL1(gene name)|psi-mi:THNSL1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000185875(gene)|ensembl:ENST00000376356(transcript)|ensembl:ENST00000524413(transcript)|interpro:IPR000623(Shikimate kinase)|interpro:IPR004450(Threonine synthase)|interpro:IPR027417|interpro:IPR029144|interpro:IPR031322|interpro:IPR036052|interpro:IPR037158|refseq:XP_016872154.1|refseq:NP_079114.3|refseq:XP_005252654.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:kAjeYzxUImucaliHBZD7OMlQAjQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96HY6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1054024|uniprotkb:A6NIU5|uniprotkb:Q9BW47|uniprotkb:C9JSZ5|ensembl:ENSP00000346483	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddrgk_human(display_long)|uniprotkb:DDRGK1(gene name)|psi-mi:DDRGK1(display_short)|uniprotkb:C20orf116(gene name synonym)|uniprotkb:UFBP1(gene name synonym)|uniprotkb:UFM1-binding and PCI domain-containing protein 1(gene name synonym)|uniprotkb:Dashurin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_076424.1|ensembl:ENSG00000198171(gene)|ensembl:ENST00000354488(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0071569"(protein ufmylation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1905050"(positive regulation of metallopeptidase activity)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR019153|interpro:IPR036388|interpro:IPR036390|reactome:R-HSA-8980692	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:a34FmuGjW3zh9eliKvmntHGU6qw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43347	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-726515|uniprotkb:Q96PU0|uniprotkb:Q96PU1|uniprotkb:Q96PU2|uniprotkb:Q96PU3|intact:EBI-28986772|ensembl:ENSP00000257552	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:msi1h_human(display_long)|uniprotkb:MSI1(gene name)|psi-mi:MSI1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002433.1|ensembl:ENSP00000257552|refseq:XP_011536663.1|ensembl:ENSG00000135097(gene)|ensembl:ENST00000257552(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0007399"(nervous system development)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034126|interpro:IPR034130|interpro:IPR035979|reactome:R-HSA-9010553	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:41/VCaTWDXjzXSisiAoG19FFVF09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NFF5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-742815|uniprotkb:Q8N5J1|uniprotkb:Q8N686|uniprotkb:Q8WU93|uniprotkb:Q8WUJ4|uniprotkb:Q96CR8|uniprotkb:Q99764|uniprotkb:Q9HBN6|ensembl:ENSP00000292180	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:fad1_human(display_long)|uniprotkb:FMN adenylyltransferase(gene name synonym)|uniprotkb:FAD pyrophosphorylase(gene name synonym)|uniprotkb:Flavin adenine dinucleotide synthase(gene name synonym)|uniprotkb:FLAD1(gene name)|psi-mi:FLAD1(display_short)|uniprotkb:PP591(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001171820.1|refseq:NP_001171821.1|refseq:NP_079483.3|refseq:NP_958800.1|ensembl:ENSG00000160688(gene)|ensembl:ENST00000292180(transcript)|go:"GO:0003919"(FMN adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006747"(FAD biosynthetic process)|go:"GO:0006771"(riboflavin metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR002500(Phosphoadenosine phosphosulphate reductase)|interpro:IPR012183(FAD synthetase, molybdopterin binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036425|mint:Q8NFF5|reactome:R-HSA-196843	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:XIktrF0PkC+W6/1cHF4l/WWtGUs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13084	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-723426|uniprotkb:Q4TT39|uniprotkb:Q96S26|uniprotkb:Q9BQD8|uniprotkb:Q9BR04|ensembl:ENSP00000199706|ensembl:ENSP00000374326|ensembl:ENSP00000497004|uniprotkb:B2RCM4|uniprotkb:D3DU46	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rm28_human(display_long)|uniprotkb:Melanoma antigen p15(gene name synonym)|uniprotkb:MRPL28(gene name)|psi-mi:MRPL28(display_short)|uniprotkb:MAAT1(gene name synonym)|uniprotkb:Melanoma-associated antigen recognized by T-lymphocytes(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL28m(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006419.2|rcsb pdb:3J7Y|ensembl:ENSG00000086504(gene)|ensembl:ENST00000199706(transcript)|ensembl:ENST00000389675(transcript)|ensembl:ENST00000648346(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|interpro:IPR026569|interpro:IPR034704|interpro:IPR037147|mint:Q13084|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011520653.1|refseq:XP_005255098.1|dip:DIP-61135N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:rgjK24sQlABM210ZM7T9mT2wxKs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P43897	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1049298|uniprotkb:Q561V7|uniprotkb:Q8TBC2|uniprotkb:Q9UQK0|uniprotkb:B4E391|uniprotkb:F5H2T7|ensembl:ENSP00000499171	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:efts_human(display_long)|uniprotkb:TSFM(gene name)|psi-mi:TSFM(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001166167.1|refseq:NP_005717.3|refseq:NP_001166166.1|refseq:NP_001166168.1|ensembl:ENSG00000123297(gene)|ensembl:ENST00000652027(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006414"(translational elongation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070125"(mitochondrial translational elongation)|go:"GO:0070129"(regulation of mitochondrial translation)|interpro:IPR001816(Translation elongation factor EFTs/EF1B)|interpro:IPR009060(UBA-like)|interpro:IPR014039(Translation elongation factor EFTs/EF1B, dimerisation)|interpro:IPR018101|interpro:IPR036402|mint:P43897|rcsb pdb:2CP9|reactome:R-HSA-5389840	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fdTdlcMKmL+EWT1bJxwfmfUuLWM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O14828	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4401333|ensembl:ENSP00000307275|ensembl:ENSP00000461521|uniprotkb:A9Z1W6|uniprotkb:B1AVS6|uniprotkb:O15128|uniprotkb:Q96FR8|uniprotkb:Q9BPY0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:scam3_human(display_long)|uniprotkb:SCAMP3(gene name)|psi-mi:SCAMP3(display_short)|uniprotkb:C1orf3(gene name synonym)|uniprotkb:PROPIN1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000116521(gene)|ensembl:ENSG00000263290(gene)|ensembl:ENST00000302631(transcript)|ensembl:ENST00000570831(transcript)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007273(SCAMP)|mint:O14828|ensembl:ENSP00000307275|ensembl:ENST00000355379|ensembl:ENSP00000347540|ensembl:ENSP00000461521|ensembl:ENST00000573013|ensembl:ENSP00000458542|refseq:NP_005689.2|refseq:NP_443069.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:q1GaoVa7cLS2hGHVUM5Nv2oX4x09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P28482	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q16836	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TCJ2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2256290|uniprotkb:Q96JZ4|uniprotkb:Q96KY7|ensembl:ENSP00000295770	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stt3b_human(display_long)|uniprotkb:STT3B(gene name)|psi-mi:STT3B(display_short)|uniprotkb:SIMP(gene name synonym)|uniprotkb:Source of immunodominant MHC-associated peptides homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_849193.1|ensembl:ENSG00000163527(gene)|ensembl:ENST00000295770(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034998"(oligosaccharyltransferase I complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:Q8TCJ2|rcsb pdb:6S7T	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:4F+9LbIZTFRoczuphd1jzuhnFDo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P11172	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-723452|uniprotkb:O00758|uniprotkb:O00759|uniprotkb:O00760|uniprotkb:Q16862|uniprotkb:Q9H3Q2|uniprotkb:Q9UG49|ensembl:ENSP00000232607|uniprotkb:B5LY68|uniprotkb:B5LY72	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:umps_human(display_long)|uniprotkb:UMPS(gene name)|psi-mi:UMPS(display_short)|uniprotkb:OK/SW-cl.21(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000364.1|interpro:IPR014732(Orotidine 5'-phosphate decarboxylase, subfamily 1, core)|interpro:IPR018089|interpro:IPR023031|interpro:IPR029057|mint:P11172|rcsb pdb:2EAW|rcsb pdb:2JGY|rcsb pdb:2P1F|rcsb pdb:2QCC|rcsb pdb:2QCD|rcsb pdb:2QCE|rcsb pdb:2QCF|rcsb pdb:2QCG|rcsb pdb:2QCH|rcsb pdb:2QCL|go:"GO:0006222"(UMP biosynthetic process)|rcsb pdb:2QCM|rcsb pdb:2QCN|rcsb pdb:2V30|rcsb pdb:2WNS|rcsb pdb:3BGG|rcsb pdb:3BGJ|rcsb pdb:3BK0|go:"GO:0007565"(female pregnancy)|rcsb pdb:3BVJ|rcsb pdb:3DBP|go:"GO:0007595"(lactation)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0044205"('de novo' UMP biosynthetic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|rcsb pdb:3EWU|rcsb pdb:3EWW|rcsb pdb:3EWY|rcsb pdb:3EWZ|rcsb pdb:3EX1|rcsb pdb:3EWX|rcsb pdb:3EX2|rcsb pdb:3EX3|rcsb pdb:3EX4|rcsb pdb:3EX6|rcsb pdb:3G3D|rcsb pdb:3G3M|rcsb pdb:3L0K|rcsb pdb:3L0N|rcsb pdb:3MI2|rcsb pdb:3MO7|rcsb pdb:3MW7|rcsb pdb:4HIB|rcsb pdb:4HKP|reactome:R-HSA-500753|ensembl:ENSG00000114491(gene)|ensembl:ENST00000232607(transcript)|go:"GO:0004588"(orotate phosphoribosyltransferase activity)|go:"GO:0004590"(orotidine-5'-phosphate decarboxylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|dip:DIP-29595N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8HKx6eTv3pMPMJQzUhhFjyGXGZI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BS26	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-541644|uniprotkb:O60319|uniprotkb:Q5VWZ7|uniprotkb:Q6UW14|uniprotkb:Q8WX67|intact:EBI-1054855|uniprotkb:Q4VXC1|ensembl:ENSP00000262455	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:erp44_human(display_long)|uniprotkb:ERP44(gene name)|psi-mi:ERP44(display_short)|uniprotkb:UNQ532/PRO1075(orf name)|uniprotkb:TXNDC4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:KIAA0573(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000023318(gene)|ensembl:ENST00000262455(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009986"(cell surface)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|mint:Q9BS26|rcsb pdb:2R2J|rcsb pdb:5GU6|rcsb pdb:5GU7|rcsb pdb:5HQP|rcsb pdb:5XWM|reactome:R-HSA-6798695|go:"GO:0009100"(glycoprotein metabolic process)|refseq:NP_055866.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TpwaFRifveb03iRPS2pEZve1kLA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P45954	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2511905|ensembl:ENSP00000357873|uniprotkb:Q96CX7|uniprotkb:B4DQ51|uniprotkb:Q5SQN6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acdsb_human(display_long)|uniprotkb:ACADSB(gene name)|psi-mi:ACADSB(display_short)|uniprotkb:2-methyl branched chain acyl-CoA dehydrogenase(gene name synonym)|uniprotkb:2-methylbutyryl-coenzyme A dehydrogenase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000196177(gene)|ensembl:ENST00000358776(transcript)|go:"GO:0003853"(2-methylacyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0016937"(short-branched-chain-acyl-CoA dehydrogenase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0102035"("isobutyryl-CoA:FAD oxidoreductase activity")|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|rcsb pdb:2JIF|reactome:R-HSA-70895|refseq:NP_001600.1|refseq:NP_001317103.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:phnlWtZGT21VyKrhWj9a3Wjfijw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15228	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-726776|uniprotkb:Q5TBH7|uniprotkb:Q9BWC2|uniprotkb:B4DNM9|ensembl:ENSP00000355607	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gnpat_human(display_long)|uniprotkb:Glycerone-phosphate O-acyltransferase(gene name synonym)|uniprotkb:"Acyl-CoA:dihydroxyacetonephosphateacyltransferase"(gene name synonym)|uniprotkb:GNPAT(gene name)|psi-mi:GNPAT(display_short)|uniprotkb:DAPAT(gene name synonym)|uniprotkb:DHAPAT(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055051.1|refseq:NP_001303279.1|ensembl:ENSG00000116906(gene)|ensembl:ENST00000366647(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0007416"(synapse assembly)|go:"GO:0007584"(response to nutrient)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016287"(glycerone-phosphate O-acyltransferase activity)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0061024"(membrane organization)|go:"GO:0070542"(response to fatty acid)|interpro:IPR002123(Phospholipid/glycerol acyltransferase)|interpro:IPR022284|interpro:IPR028353|interpro:IPR041728|reactome:R-HSA-1483166|reactome:R-HSA-75896|reactome:R-HSA-9033241	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:guKwW4vdqhvUhZOFcX40s+LLk3k9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P51648	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H9P8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11081371|uniprotkb:Q9BRR1|ensembl:ENSP00000267436|ensembl:ENSP00000405559	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:l2hdh_human(display_long)|uniprotkb:L2HGDH(gene name)|psi-mi:L2HGDH(display_short)|uniprotkb:C14orf160(gene name synonym)|uniprotkb:Duranin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_079160.1|refseq:XP_005268132.1|ensembl:ENSG00000087299(gene)|ensembl:ENST00000267436(transcript)|ensembl:ENST00000421284(transcript)|go:"GO:0003973"("(S)-2-hydroxy-acid oxidase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0047545"(2-hydroxyglutarate dehydrogenase activity)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR036188|reactome:R-HSA-880009	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:EMg3mk/BoaMCMi3AegPe/uX1/149606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P45974	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-741277|ensembl:ENSP00000229268|uniprotkb:Q96J22|uniprotkb:D3DUS7|uniprotkb:D3DUS8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ubp5_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 5(gene name synonym)|uniprotkb:Deubiquitinating enzyme 5(gene name synonym)|uniprotkb:Isopeptidase T(gene name synonym)|uniprotkb:USP5(gene name)|psi-mi:USP5(display_short)|uniprotkb:ISOT(gene name synonym)|uniprotkb:Ubiquitin thioesterase 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000111667(gene)|ensembl:ENST00000229268(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071108"(protein K48-linked deubiquitination)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR009060(UBA-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016652(Ubiquitinyl hydrolase)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|interpro:IPR041432|interpro:IPR041812|mint:P45974|rcsb pdb:2DAG|rcsb pdb:2DAK|rcsb pdb:2G43|rcsb pdb:2G45|rcsb pdb:3IHP|rcsb pdb:6DXH|rcsb pdb:6DXT|rcsb pdb:6NFT|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|rcsb pdb:6P9G|rcsb pdb:7MS5|rcsb pdb:7MS6|rcsb pdb:7MS7|reactome:R-HSA-5689880|reactome:R-HSA-8866652|refseq:NP_001092006.1|refseq:NP_003472.2|dip:DIP-34459N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9wmOnaEu1N5ZY3E4UiHp2D9f9j89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HCU5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2553896|uniprotkb:Q9UH94|ensembl:ENSP00000260643|uniprotkb:Q53SZ8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:preb_human(display_long)|uniprotkb:SEC12(gene name synonym)|uniprotkb:Mammalian guanine nucleotide exchange factor mSec12(gene name synonym)|uniprotkb:PREB(gene name)|psi-mi:PREB(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_037520.1|ensembl:ENSG00000138073(gene)|ensembl:ENST00000260643(transcript)|go:"GO:0003400"(regulation of COPII vesicle coating)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051020"(GTPase binding)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|rcsb pdb:5TF2|reactome:R-HSA-204005|reactome:R-HSA-381038|reactome:R-HSA-5694530|refseq:NP_001317414.1|refseq:NP_001317415.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3xjABrP1KtfZUMb/BSbe8ZN6dJ49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TAE8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-372506|uniprotkb:Q8IVM3|uniprotkb:Q8TE51|uniprotkb:Q969P9|uniprotkb:Q9BSM6|intact:EBI-28983431|ensembl:ENSP00000323065	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:g45ip_human(display_long)|uniprotkb:39S ribosomal protein L59, mitochondrial(gene name synonym)|uniprotkb:MRPL59(gene name synonym)|uniprotkb:CR6-interacting factor 1(gene name synonym)|uniprotkb:CKII beta-associating protein(gene name synonym)|uniprotkb:Papillomavirus L2-interacting nuclear protein 1(gene name synonym)|uniprotkb:p53-responsive gene 6 protein(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL64(gene name synonym)|uniprotkb:GADD45GIP1(gene name)|psi-mi:GADD45GIP1(display_short)|uniprotkb:PLINP1(gene name synonym)|uniprotkb:PRG6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_443082.2|ensembl:ENSP00000323065|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000179271(gene)|ensembl:ENST00000316939(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005840"(ribosome)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR018472|interpro:IPR043035|mint:Q8TAE8|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:lFY+2Pev2sxqaW9nhzemL0QO52s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75600	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2959690|ensembl:ENSP00000248924|uniprotkb:Q96CA9|uniprotkb:E2QC23|uniprotkb:Q6ZWF1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kbl_human(display_long)|uniprotkb:GCAT(gene name)|psi-mi:GCAT(display_short)|uniprotkb:KBL(gene name synonym)|uniprotkb:Aminoacetone synthase(gene name synonym)|uniprotkb:Glycine acetyltransferase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000100116(gene)|ensembl:ENST00000248924(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0008890"(glycine C-acetyltransferase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0019518"(L-threonine catabolic process to glycine)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR011282(2-amino-3-ketobutyrate coenzyme A ligase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|reactome:R-HSA-8849175|refseq:NP_055106.1|refseq:NP_001165161.1|refseq:XP_005261467.1|refseq:XP_016884166.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:JcxSdpqnWgMx3m5s6nO38OjqO+I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BQ95	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-712452|uniprotkb:Q9NYI1|uniprotkb:Q96HQ7|ensembl:ENSP00000270517|uniprotkb:E9PAN9|uniprotkb:K7EMM0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ecsit_human(display_long)|uniprotkb:Protein SITPEC(gene name synonym)|uniprotkb:ECSIT(gene name)|psi-mi:ECSIT(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000130159(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0045087"(innate immune response)|go:"GO:0051341"(regulation of oxidoreductase activity)|go:"GO:0061635"(regulation of protein complex stability)|interpro:IPR010418(ECSIT)|interpro:IPR029342|reactome:R-HSA-166058|reactome:R-HSA-6799198|reactome:R-HSA-975138|reactome:R-HSA-975871|ensembl:ENST00000270517(transcript)|refseq:NP_001230133.1|refseq:NP_001135937.1|refseq:NP_001135936.1|refseq:NP_057665.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9gpZoQnhuP1vkFOPhXHkF1kHB8Q9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y305	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2548214|ensembl:ENSP00000336580|uniprotkb:B3KNC9|uniprotkb:B7ZM94	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acot9_human(display_long)|uniprotkb:ACOT9(gene name)|psi-mi:ACOT9(display_short)|uniprotkb:Acyl-CoA thioester hydrolase 9(gene name synonym)|uniprotkb:CGI-16(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000123130(gene)|ensembl:ENST00000336430(transcript)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|interpro:IPR029069|interpro:IPR033120|mint:Q9Y305|reactome:R-HSA-77289|refseq:NP_001028755.2|refseq:NP_001032248.1|refseq:NP_001317188.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:WbPOPMGV/9XQRxLufTKCXvYQH/Y9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O94925	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043737|uniprotkb:Q9UL05|uniprotkb:Q9UL06|uniprotkb:Q9UL07|uniprotkb:Q9UN40|ensembl:ENSP00000317379	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:glsk_human(display_long)|uniprotkb:GLS(gene name)|psi-mi:GLS(display_short)|uniprotkb:GLS1(gene name synonym)|uniprotkb:KIAA0838(gene name synonym)|uniprotkb:L-glutamine amidohydrolase(gene name synonym)|uniprotkb:K-glutaminase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001243239.1|refseq:NP_055720.3|dip:DIP-50591N|ensembl:ENSG00000115419(gene)|ensembl:ENST00000320717(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0004359"(glutaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0090461"(glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007268"(chemical synaptic transmission)|interpro:IPR041541|mint:O94925|rcsb pdb:3CZD|rcsb pdb:3UNW|rcsb pdb:3UO9|rcsb pdb:3VOY|rcsb pdb:3VOZ|rcsb pdb:3VP0|rcsb pdb:3VP1|rcsb pdb:3VP2|rcsb pdb:3VP3|rcsb pdb:3VP4|rcsb pdb:5D3O|rcsb pdb:5FI2|rcsb pdb:5FI6|rcsb pdb:5FI7|rcsb pdb:5HL1|rcsb pdb:5I94|rcsb pdb:5JYO|rcsb pdb:5JYP|rcsb pdb:5U0I|rcsb pdb:5U0J|rcsb pdb:5UQE|rcsb pdb:5WJ6|rcsb pdb:6LOX|rcsb pdb:6UJG|rcsb pdb:6UJM|rcsb pdb:6UK6|rcsb pdb:6UKB|rcsb pdb:4O7D|rcsb pdb:6UL9|rcsb pdb:6ULA|rcsb pdb:6UMC|rcsb pdb:6UMD|rcsb pdb:6UME|rcsb pdb:6UMF|reactome:R-HSA-210500|reactome:R-HSA-5628897|reactome:R-HSA-8964539|rcsb pdb:6ULJ	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:IV2jY1Qj63eTVPmTndDavjoUM2w9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UBV2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UDR5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1237169|uniprotkb:O95462|ensembl:ENSP00000377040|ensembl:ENSP00000403768|ensembl:ENSP00000505381|ensembl:ENSP00000505958	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:aass_human(display_long)|uniprotkb:AASS(gene name)|psi-mi:AASS(display_short)|uniprotkb:LKR/SDH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005754.2|ensembl:ENSG00000008311(gene)|ensembl:ENST00000393376(transcript)|ensembl:ENST00000417368(transcript)|ensembl:ENST00000679511(transcript)|ensembl:ENST00000679864(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004753"(saccharopine dehydrogenase activity)|go:"GO:0004754"("saccharopine dehydrogenase (NAD+, L-lysine-forming) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006554"(lysine catabolic process)|go:"GO:0019878"(lysine biosynthetic process via aminoadipic acid)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047130"("saccharopine dehydrogenase (NADP+, L-lysine-forming) activity")|go:"GO:0047131"("saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity")|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR032095|interpro:IPR036291|rcsb pdb:5L76|rcsb pdb:5L78|rcsb pdb:5O1N|rcsb pdb:5O1O|rcsb pdb:5O1P|reactome:R-HSA-71064	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:UKSIs4pNgKcCqgLa0h1pDf1znnQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92947	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1236978|uniprotkb:O14719|uniprotkb:A8K2Z2|ensembl:ENSP00000222214|ensembl:ENSP00000466845	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:gcdh_human(display_long)|uniprotkb:GCDH(gene name)|psi-mi:GCDH(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000150.1|refseq:NP_039663.1|ensembl:ENSG00000105607(gene)|ensembl:ENST00000222214(transcript)|ensembl:ENST00000591470(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004361"(glutaryl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006568"(tryptophan metabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q92947|rcsb pdb:1SIQ|rcsb pdb:1SIR|rcsb pdb:2R0M|rcsb pdb:2R0N|reactome:R-HSA-71064|go:"GO:0050660"(flavin adenine dinucleotide binding)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:W192IQEAyP1SdNxhI62Fh8C2UPU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P13674	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1237386|uniprotkb:Q15082|uniprotkb:Q15083|uniprotkb:Q5VSQ5|uniprotkb:C9JL12|ensembl:ENSP00000307318|ensembl:ENSP00000378353	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:p4ha1_human(display_long)|uniprotkb:P4HA1(gene name)|psi-mi:P4HA1(display_short)|uniprotkb:P4HA(gene name synonym)|uniprotkb:Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000908.2|refseq:NP_001017962.1|refseq:NP_001136067.1|refseq:NP_001136068.1|dip:DIP-38180N|ensembl:ENSG00000122884(gene)|ensembl:ENST00000307116(transcript)|ensembl:ENST00000394890(transcript)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031418"(L-ascorbic acid binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005123("2OG-Fe(II) oxygenase")|interpro:IPR006620(Prolyl 4-hydroxylase, alpha subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013547(Prolyl 4-hydroxylase alpha-subunit, N-terminal)|interpro:IPR019734|mint:P13674|rcsb pdb:1TJC|rcsb pdb:2V5F|rcsb pdb:2YQ8|rcsb pdb:4BT8|rcsb pdb:4BT9|rcsb pdb:4BTA|rcsb pdb:4BTB|reactome:R-HSA-1650814|go:"GO:0043231"(intracellular membrane-bounded organelle)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Yo9hgWVJ5iUGITVWKfvjhTNX1lk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UG63	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2959697|ensembl:ENSP00000287844|uniprotkb:Q96TE8|uniprotkb:O60864|uniprotkb:Q75MJ0|uniprotkb:Q75MJ1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:abcf2_human(display_long)|uniprotkb:ABCF2(gene name)|psi-mi:ABCF2(display_short)|uniprotkb:Iron-inhibited ABC transporter 2(gene name synonym)|uniprotkb:HUSSY-18(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000033050(gene)|ensembl:ENST00000287844(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|mint:Q9UG63|go:"GO:0016020"(membrane)|refseq:NP_005683.2|refseq:NP_009120.1|refseq:XP_016867128.1|refseq:XP_016867129.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TdGWfZ4OYohgxKLL1uyz7X+FWmQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96JJ7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2514069|intact:EBI-28973673|uniprotkb:B3KV75|uniprotkb:Q52LT7|uniprotkb:Q8N5J0|uniprotkb:Q9NWJ9|ensembl:ENSP00000299608	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tmx3_human(display_long)|uniprotkb:TMX3(gene name)|psi-mi:TMX3(display_short)|uniprotkb:KIAA1830(gene name synonym)|uniprotkb:TXNDC10(gene name synonym)|uniprotkb:Thioredoxin-related transmembrane protein 3(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 10(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000299608|ensembl:ENST00000562706|ensembl:ENSP00000457262|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|reactome:R-HSA-114608|ensembl:ENST00000299608(transcript)|ensembl:ENSG00000166479(gene)|refseq:NP_061895.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Qber8pA1sCprlKl8Yoc5XtVEd5s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BQ52	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-718223|uniprotkb:Q6IA94|uniprotkb:Q9HAS8|uniprotkb:Q9HAS9|uniprotkb:Q9NVT1|uniprotkb:B4DPL9|ensembl:ENSP00000337445	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rnz2_human(display_long)|uniprotkb:Ribonuclease Z 2(gene name synonym)|uniprotkb:tRNase Z 2(gene name synonym)|uniprotkb:tRNA 3 endonuclease 2(gene name synonym)|uniprotkb:ElaC homolog protein 2(gene name synonym)|uniprotkb:Heredity prostate cancer protein 2(gene name synonym)|uniprotkb:ELAC2(gene name)|psi-mi:ELAC2(display_short)|uniprotkb:HPC2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060597.4|refseq:NP_776065.1|refseq:NP_001159434.1|ensembl:ENSG00000006744(gene)|ensembl:ENST00000338034(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004549"(tRNA-specific ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0042781"(3'-tRNA processing endoribonuclease activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0072684"(mitochondrial tRNA 3'-trailer cleavage, endonucleolytic)|go:"GO:0090646"(mitochondrial tRNA processing)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR027794|interpro:IPR036866|reactome:R-HSA-6784531|reactome:R-HSA-6785470|reactome:R-HSA-8868766|reactome:R-HSA-9708296	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:tWcWt1K6Dtnei9RcrGOL4rQTDUo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NU22	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400|ensembl:ENSP00000486270|ensembl:ENSP00000499843|ensembl:ENSP00000499895	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055426.1|ensembl:ENSG00000112159(gene)|ensembl:ENSG00000288121(gene)|ensembl:ENST00000369393(transcript)|ensembl:ENST00000629399(transcript)|ensembl:ENST00000672983(transcript)|ensembl:ENST00000673332(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|mint:Q9NU22|go:"GO:0005829"(cytosol)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q86UY8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2682594|uniprotkb:Q9P2T3|uniprotkb:Q9P2T2|uniprotkb:Q9NUM7|ensembl:ENSP00000376615	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nt5d3_human(display_long)|uniprotkb:GNN(gene name synonym)|uniprotkb:TU12B1-TY(gene name synonym)|uniprotkb:GRP94-neighboring nucleotidase(gene name synonym)|uniprotkb:NT5DC3(gene name)|psi-mi:NT5DC3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001026871.1|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|ensembl:ENSG00000111696(gene)|ensembl:ENST00000392876(transcript)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0043235"(receptor complex)|go:"GO:0046872"(metal ion binding)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RosGgCpFaCMvbM9Ukz2gDz0Kjxw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00483	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P55786	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1046129|uniprotkb:Q6P145|uniprotkb:Q9NP16|uniprotkb:Q9UEM2|ensembl:ENSP00000320324|ensembl:ENSP00000503682|uniprotkb:B7Z463	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:psa_human(display_long)|uniprotkb:NPEPPS(gene name)|psi-mi:NPEPPS(display_short)|uniprotkb:PSA(gene name synonym)|uniprotkb:Cytosol alanyl aminopeptidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006301.3|ensembl:ENSG00000141279(gene)|ensembl:ENST00000322157(transcript)|ensembl:ENST00000677120(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|reactome:R-HSA-983168|refseq:NP_001317186.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:gDl9SPlJhCOhA8uF4OEw+lIPh2M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:A0FGR8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P46977	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O94874	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1048088|intact:EBI-2798769|uniprotkb:Q8N765|uniprotkb:Q9NTQ0|uniprotkb:A0PJ53|uniprotkb:B4DJ57|uniprotkb:C0H5X5|ensembl:ENSP00000358283	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ufl1_human(display_long)|uniprotkb:UFL1(gene name)|psi-mi:UFL1(display_short)|uniprotkb:E3 UFM1-protein transferase 1(gene name synonym)|uniprotkb:KIAA0776(gene name synonym)|uniprotkb:Novel LZAP-binding protein(gene name synonym)|uniprotkb:RCAD(gene name synonym)|uniprotkb:Regulator of C53/LZAP and DDRGK1(gene name synonym)|uniprotkb:NLBP(gene name synonym)|uniprotkb:MAXER(gene name synonym)|uniprotkb:Multiple alpha-helix protein located at ER(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056138.1|ensembl:ENSG00000014123(gene)|ensembl:ENST00000369278(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0016570"(histone modification)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0061666"(UFM1 ligase activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0071568"(UFM1 transferase activity)|go:"GO:0071569"(protein ufmylation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1990592"(protein K69-linked ufmylation)|interpro:IPR018611|mint:O94874|reactome:R-HSA-983168	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:wiJotyDNle7GoYzFkOif0TFNr2w9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96CS3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O96005	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2873194|ensembl:ENSP00000336994|uniprotkb:Q53ET6|uniprotkb:Q9BSS5|uniprotkb:B3KQH2|uniprotkb:B4DDS3|uniprotkb:B4E2X9|uniprotkb:B7Z9X9|uniprotkb:F5H8J3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:clpt1_human(display_long)|uniprotkb:CLPTM1(gene name)|psi-mi:CLPTM1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000104853(gene)|ensembl:ENST00000337392(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:O96005|refseq:NP_001285.1|refseq:NP_001269104.1|refseq:NP_001269105.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:CFQ2o5QzCYtIDaxlVtJlA6FEMgU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P05091	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-711703|uniprotkb:Q03639|uniprotkb:Q6IB13|uniprotkb:Q6IV71|uniprotkb:B4DW54|uniprotkb:E7EUE5|ensembl:ENSP00000261733	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:aldh2_human(display_long)|uniprotkb:ALDH class 2(gene name synonym)|uniprotkb:ALDHI(gene name synonym)|uniprotkb:ALDH-E2(gene name synonym)|uniprotkb:ALDH2(gene name)|psi-mi:ALDH2(display_short)|uniprotkb:ALDM(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000681.2|refseq:NP_001191818.1|dip:DIP-40262N|ensembl:ENSG00000111275(gene)|ensembl:ENST00000261733(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P05091|rcsb pdb:1CW3|rcsb pdb:1NZW|rcsb pdb:1NZX|rcsb pdb:1NZZ|rcsb pdb:1O00|rcsb pdb:1O01|rcsb pdb:1O02|rcsb pdb:1O04|rcsb pdb:1O05|rcsb pdb:1ZUM|rcsb pdb:2ONM|rcsb pdb:2ONN|rcsb pdb:2ONO|rcsb pdb:2ONP|rcsb pdb:2VLE|rcsb pdb:3INJ|rcsb pdb:3INL|rcsb pdb:3N80|rcsb pdb:3N81|rcsb pdb:3N82|rcsb pdb:3N83|rcsb pdb:3SZ9|rcsb pdb:4FQF|rcsb pdb:4FR8|rcsb pdb:4KWF|rcsb pdb:4KWG|rcsb pdb:5L13|reactome:R-HSA-380612|reactome:R-HSA-71384	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:XvszkFUJP4cXHCYokY16c+LeDEI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H857	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-359244|uniprotkb:O95888|uniprotkb:Q96C80|uniprotkb:Q9H9Z8|uniprotkb:C9JTZ6|uniprotkb:E9PAL9|intact:EBI-11044897|ensembl:ENSP00000302468	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nt5d2_human(display_long)|uniprotkb:NT5DC2(gene name)|psi-mi:NT5DC2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001127703.1|refseq:NP_075059.1|refseq:XP_005265463.1|refseq:XP_006713368.1|ensembl:ENSG00000168268(gene)|ensembl:ENST00000307076(transcript)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:nfT/9N1bWVadX70eY1G0GS9pS9U9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15155	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-373107|uniprotkb:P78421|uniprotkb:Q8IW21|uniprotkb:Q96DG0|ensembl:ENSP00000287667|ensembl:ENSP00000482008	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nomo1_human(display_long)|uniprotkb:PM5(gene name synonym)|uniprotkb:NOMO1(gene name)|psi-mi:NOMO1(display_short)|uniprotkb:pM5 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055102.3|interpro:IPR013783(Immunoglobulin-like fold)|ensembl:ENSG00000103512(gene)|ensembl:ENSG00000274779(gene)|ensembl:ENST00000287667(transcript)|ensembl:ENST00000619292(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043022"(ribosome binding)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR041033|mint:Q15155	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Dvi85VHhwmSC8qfJp1ufqUqPLdE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:A3KMH1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-308657|uniprotkb:Q5JTP6|uniprotkb:Q5VW08|uniprotkb:Q7Z6I9|uniprotkb:Q86YC9|uniprotkb:Q8N3E4|uniprotkb:O60310|ensembl:ENSP00000368612	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:vwa8_human(display_long)|uniprotkb:VWA8(gene name)|psi-mi:VWA8(display_short)|uniprotkb:KIAA0564(gene name synonym)|uniprotkb:PEX7-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000102763(gene)|ensembl:ENST00000379310(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|refseq:NP_001009814.1|refseq:NP_055873.1|refseq:XP_016875963.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:IOalBj68cHFF4BsViQ+eeXQZiRY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P50213	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-355999|uniprotkb:D3DW83|uniprotkb:Q9H3X0|ensembl:ENSP00000299518	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:idh3a_human(display_long)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005521.1|interpro:IPR024084|ensembl:ENSG00000166411(gene)|ensembl:ENST00000299518(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|mint:P50213|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-71403	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:JvAUAMJ0DcgnIfvy/vlfRyXYzhE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43837	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-725377|uniprotkb:O95106|uniprotkb:Q5JXS8|uniprotkb:Q9NQ06|uniprotkb:Q9NQ07|uniprotkb:Q9UEX0|uniprotkb:Q9UG99|uniprotkb:B2RDR1|uniprotkb:D3DVX2|uniprotkb:D3DVX3|uniprotkb:Q9NUZ0|ensembl:ENSP00000370223	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:idh3b_human(display_long)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_008830.2|refseq:NP_777280.1|ensembl:ENSG00000101365(gene)|ensembl:ENST00000380843(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:O43837|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:7CE3|reactome:R-HSA-71403|refseq:NP_001317692.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:in3sFQUqN4ZtqBii7BotVro104A9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43809	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9P2I0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043224|uniprotkb:Q6NSJ1|uniprotkb:Q9H3W7|ensembl:ENSP00000298875|uniprotkb:B3KME1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cpsf2_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 100 kDa subunit(gene name synonym)|uniprotkb:CPSF2(gene name)|psi-mi:CPSF2(display_short)|uniprotkb:CPSF100(gene name synonym)|uniprotkb:KIAA1367(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR025069|interpro:IPR027075|interpro:IPR035639|interpro:IPR036866|mint:Q9P2I0|rcsb pdb:6URG|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|ensembl:ENSG00000165934(gene)|ensembl:ENST00000298875(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016020"(membrane)|refseq:NP_059133.1|refseq:NP_001309201.1|dip:DIP-42500N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RYiaQ8q9VM7htGre4S8PkSQaCz89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q10570	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UKF6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y2Z2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2864055|uniprotkb:Q5SWL2|uniprotkb:Q8NDN7|uniprotkb:Q5SWL4|uniprotkb:B3KQB5|uniprotkb:Q8WZ57|uniprotkb:Q5SWL3|uniprotkb:Q9BS06|uniprotkb:Q96FE6|ensembl:ENSP00000359323	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mto1_human(display_long)|uniprotkb:MTO1(gene name)|psi-mi:MTO1(display_short)|uniprotkb:CGI-02(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001116698.1|refseq:NP_036255.2|refseq:NP_598400.1|ensembl:ENSG00000135297(gene)|ensembl:ENST00000370300(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0030488"(tRNA methylation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0070899"(mitochondrial tRNA wobble uridine modification)|interpro:IPR002218(Glucose-inhibited division protein A)|interpro:IPR004416(Glucose-inhibited division protein A subfamily)|interpro:IPR020595|interpro:IPR026904|interpro:IPR036188|interpro:IPR040131|interpro:IPR044920|mint:Q9Y2Z2|reactome:R-HSA-6787450	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:SEHqgclQ+heHG/iQNequUOKLKvY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P34896	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-715117|uniprotkb:Q9UMD1|uniprotkb:Q9UMD2|uniprotkb:Q96HY0|uniprotkb:D3DXD0|uniprotkb:B4DPM9|ensembl:ENSP00000492715|ensembl:ENSP00000495756|ensembl:ENSP00000318868	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:glyc_human(display_long)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:SHMT1(gene name)|psi-mi:SHMT1(display_short)|uniprotkb:Serine methylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001268715.1|refseq:NP_004160.3|refseq:NP_683718.1|refseq:XP_016880446.1|refseq:XP_016880447.1|refseq:XP_011522294.1|refseq:XP_005256824.1|ensembl:ENSG00000176974(gene)|ensembl:ENSG00000284320(gene)|ensembl:ENST00000316694(transcript)|ensembl:ENST00000640392(transcript)|ensembl:ENST00000644141(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0036094"(small molecule binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070905"(serine binding)|go:"GO:1904482"(cellular response to tetrahydrofolate)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|rcsb pdb:1BJ4|rcsb pdb:6FL5|rcsb pdb:6M5W|reactome:R-HSA-196757|reactome:R-HSA-71262	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:OoGscelaCrK8ytz7Nyo7Msm8epE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7Z4G4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2515608|uniprotkb:Q5JY11|uniprotkb:Q6PGQ5|uniprotkb:Q9HC13|uniprotkb:E1P570|ensembl:ENSP00000333934	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:trm11_human(display_long)|uniprotkb:TRMT11(gene name)|psi-mi:TRMT11(display_short)|uniprotkb:C6orf75(gene name synonym)|uniprotkb:tRNA guanosine-2'-O-methyltransferase TRM11 homolog(gene name synonym)|uniprotkb:MDS024(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001026882.2|ensembl:ENSG00000066651(gene)|ensembl:ENST00000334379(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004809"("tRNA (guanine-N2-)-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0008168"(methyltransferase activity)|interpro:IPR000241(Putative RNA methylase)|interpro:IPR002052(N-6 adenine-specific DNA methylase, conserved site)|interpro:IPR016691(tRNA guanosine-2'-O-methyltransferase, TRM11)|interpro:IPR029063|reactome:R-HSA-6782315	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:BCGxR/3+huZv9IKwcnXvO/PHzlY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O60678	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2809009|uniprotkb:B4DUC7|uniprotkb:A0A0A0MSN7|ensembl:ENSP00000331879	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:anm3_human(display_long)|uniprotkb:PRMT3(gene name)|psi-mi:PRMT3(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005779.1|ensembl:ENSG00000185238(gene)|ensembl:ENST00000331079(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900053"(negative regulation of retinoic acid biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236|mint:O60678|rcsb pdb:2FYT|rcsb pdb:3SMQ|rcsb pdb:4HSG|rcsb pdb:4QQN|rcsb pdb:4RYL|reactome:R-HSA-3214858|reactome:R-HSA-8876725	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:XtFHON3qMCvjDhtN8RpXJo9KODU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UI30	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-373326|uniprotkb:Q3MHC7|uniprotkb:Q8N2Z4|uniprotkb:B2R539|uniprotkb:J3KNG5|ensembl:ENSP00000438349	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tr112_human(display_long)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym)|uniprotkb:AD-001(orf name)|uniprotkb:HSPC152(orf name)|uniprotkb:HSPC170(orf name)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001273011.1|refseq:NP_057488.1|ensembl:ENSG00000173113(gene)|ensembl:ENST00000544844(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0018364"(peptidyl-glutamine methylation)|go:"GO:0030488"(tRNA methylation)|go:"GO:0031167"(rRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070476"("rRNA (guanine-N7)-methylation")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR005651(Protein of unknown function DUF343)|mint:Q9UI30|rcsb pdb:6G4W|rcsb pdb:6H1D|rcsb pdb:6H1E|rcsb pdb:6H2U|rcsb pdb:6H2V|rcsb pdb:6K0X|rcsb pdb:6KHS|rcsb pdb:6KMR|rcsb pdb:6KMS|rcsb pdb:6PED|reactome:R-HSA-156581|reactome:R-HSA-6782315|reactome:R-HSA-6790901|reactome:R-HSA-72764|interpro:IPR039127	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:N3kvBRpRMFAeB5AYgOmAvs34u+c9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q99873	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75153	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-308505|uniprotkb:Q6AHY2|uniprotkb:Q6P3X7|uniprotkb:Q6ZUG8|uniprotkb:Q8N4U7|uniprotkb:Q9BTA3|uniprotkb:Q9H979|ensembl:ENSP00000388872|ensembl:ENSP00000458986	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:clu_human(display_long)|uniprotkb:CLUH(gene name)|psi-mi:CLUH(display_short)|uniprotkb:KIAA0664(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056044.3|ensembl:ENSG00000132361(gene)|ensembl:ENST00000435359(transcript)|ensembl:ENST00000570628(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023231|interpro:IPR025697|interpro:IPR027523|interpro:IPR028275|interpro:IPR033646	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9605WkS82JBvT0JZ1fkpxe3SqRc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q02218	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-747213|intact:EBI-1210683|uniprotkb:Q9UDX0|uniprotkb:D3DVL0|uniprotkb:B4E2U9|uniprotkb:E9PBM1|uniprotkb:Q96DD3|ensembl:ENSP00000222673	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:odo1_human(display_long)|uniprotkb:OGDH(gene name)|psi-mi:OGDH(display_short)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002532.2|refseq:NP_001003941.1|refseq:NP_001158508.1|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0021756"(striatum development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|rcsb pdb:3ERY|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403|ensembl:ENSG00000105953(gene)|ensembl:ENST00000222673(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|dip:DIP-39353N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:B9CSRCmhDYg7n5jSpuDlr2mrxDg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8NB78	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2509999|ensembl:ENSP00000499208|uniprotkb:Q6AI15|uniprotkb:Q6ZUU4|uniprotkb:Q96EL7|uniprotkb:Q5TGV3|uniprotkb:Q8N258|uniprotkb:A2A2C5|uniprotkb:A2A2C6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:kdm1b_human(display_long)|uniprotkb:KDM1B(gene name)|psi-mi:KDM1B(display_short)|uniprotkb:C6orf193(gene name synonym)|uniprotkb:AOF1(gene name synonym)|uniprotkb:LSD2(gene name synonym)|uniprotkb:Lysine-specific histone demethylase 2(gene name synonym)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000165097(gene)|ensembl:ENST00000650836(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034649"("obsolete histone demethylase activity (H3-monomethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0071949"(FAD binding)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR036188|interpro:IPR036388|rcsb pdb:4FWE|rcsb pdb:4FWF|rcsb pdb:4FWJ|rcsb pdb:4GU0|rcsb pdb:4GU1|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GUT|rcsb pdb:4GUU|rcsb pdb:4HSU|rcsb pdb:6R1U|rcsb pdb:6R25|reactome:R-HSA-3214842|reactome:R-HSA-5689603|reactome:R-HSA-9029569|refseq:NP_694587.3|refseq:XP_005248983.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:37lP46UxrdbQmFoKabg6UdpVETg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5JRX3	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2432778|uniprotkb:B4E0J8|uniprotkb:E7ES23|uniprotkb:B3KMJ6|uniprotkb:O95204|uniprotkb:Q2M2G6|uniprotkb:Q4VBR1|uniprotkb:Q5JRW7|uniprotkb:Q7L5Z7|uniprotkb:Q9BSI6|uniprotkb:Q9BVJ5|uniprotkb:Q9UPP8|uniprotkb:C9JSL2|ensembl:ENSP00000224949	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:prep_human(display_long)|uniprotkb:PITRM1(gene name)|psi-mi:PITRM1(display_short)|uniprotkb:KIAA1104(gene name synonym)|uniprotkb:MP1(gene name synonym)|uniprotkb:Pitrilysin metalloproteinase 1(gene name synonym)|uniprotkb:PREP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001229236.1|refseq:NP_001229238.1|refseq:NP_055704.2|dip:DIP-52900N|ensembl:ENSG00000107959(gene)|ensembl:ENST00000224949(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006508"(proteolysis)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|interpro:IPR013578(Peptidase M16C associated)|mint:Q5JRX3|rcsb pdb:4L3T|rcsb pdb:4NGE|rcsb pdb:4RPU|reactome:R-HSA-1268020	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:1kEY/XJB5fwgNRoM9u9ZGT+VrS09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5VT66	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-11903927|uniprotkb:A8K447|uniprotkb:B2D078|uniprotkb:Q5VVS9|uniprotkb:Q5VVT0|uniprotkb:Q5VVT1|uniprotkb:Q8N9P5|uniprotkb:Q96FN8|uniprotkb:Q9H6C7|ensembl:ENSP00000355877	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:marc1_human(display_long)|uniprotkb:MTARC1(gene name)|psi-mi:MTARC1(display_short)|uniprotkb:MARC1(gene name synonym)|uniprotkb:MOSC1(gene name synonym)|uniprotkb:Molybdenum cofactor sulfurase C-terminal domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_073583.3|refseq:XP_011508202.1|refseq:XP_011508206.1|ensembl:ENSG00000186205(gene)|ensembl:ENST00000366910(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016661"(oxidoreductase activity, acting on other nitrogenous compounds as donors)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042126"(nitrate metabolic process)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0051410"(detoxification of nitrogen compound)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|go:"GO:0098809"(nitrite reductase activity)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR005302(Molybdenum cofactor sulphurase, C-terminal)|interpro:IPR005303(MOSC, N-terminal beta barrel)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|rcsb pdb:6FW2|reactome:R-HSA-211945	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:MVnfGK30icFS28a9p6qf739MKYs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y5Q9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1054873|uniprotkb:Q4ZG48|uniprotkb:Q86XJ8|uniprotkb:Q8WX84|uniprotkb:Q96B44|uniprotkb:Q9H5I8|uniprotkb:Q9NT97|intact:EBI-1237212|ensembl:ENSP00000263956	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tf3c3_human(display_long)|uniprotkb:GTF3C3(gene name)|psi-mi:GTF3C3(display_short)|uniprotkb:Transcription factor IIIC subunit gamma(gene name synonym)|uniprotkb:Transcription factor IIIC 102 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001193703.1|refseq:NP_036218.1|ensembl:ENSG00000119041(gene)|ensembl:ENST00000263956(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039340|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:cF53nd62xSXQfZerd7bdfB2KUgk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P40938	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1055010|intact:EBI-2512011|uniprotkb:O15252|intact:EBI-1169853|uniprotkb:Q5W0E8|uniprotkb:C9JU95|ensembl:ENSP00000369411	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rfc3_human(display_long)|uniprotkb:RFC3(gene name)|psi-mi:RFC3(display_short)|uniprotkb:Activator 1 subunit 3(gene name synonym)|uniprotkb:Replication factor C 38 kDa subunit(gene name synonym)|uniprotkb:Activator 1 38 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002906.1|refseq:NP_853536.2|ensembl:ENSG00000133119(gene)|ensembl:ENST00000380071(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0046683"(response to organophosphorus)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR027417|mint:P40938|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-6804756|dip:DIP-36432N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:XaK3OCno6yS3ubSiJhdBrW52VAw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P40937	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-712376|ensembl:ENSP00000408295|uniprotkb:A8MZ62|uniprotkb:B3KSX8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_031396.1|refseq:NP_853556.2|ensembl:ENSG00000111445(gene)|ensembl:ENST00000454402(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P40937|rcsb pdb:1LFS|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:XP_011536945.1|refseq:XP_011536947.1|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P12004	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P49792	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-973138|intact:EBI-28970106|ensembl:ENSP00000283195|uniprotkb:Q13074|uniprotkb:Q15280|uniprotkb:Q53TE2|uniprotkb:Q59FH7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rbp2_human(display_long)|uniprotkb:RANBP2(gene name)|psi-mi:RANBP2(display_short)|uniprotkb:NUP358(gene name synonym)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Nuclear pore complex protein Nup358(gene name synonym)|uniprotkb:Nucleoporin Nup358(gene name synonym)|uniprotkb:358 kDa nucleoporin(gene name synonym)|uniprotkb:p270(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000153201(gene)|ensembl:ENST00000283195(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|reactome:R-HSA-168271|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|mint:P49792|reactome:R-HSA-168276|rcsb pdb:1RRP|reactome:R-HSA-168325|reactome:R-HSA-168333|rcsb pdb:1XKE|rcsb pdb:1Z5S|rcsb pdb:2LAS|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:4GA0|rcsb pdb:4I9Y|rcsb pdb:4L6E|rcsb pdb:4LQW|rcsb pdb:5CLL|rcsb pdb:5CLQ|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-170822|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-180746|reactome:R-HSA-9648025|ensembl:ENSP00000283195|refseq:NP_006258.3|dip:DIP-37654N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:KB+rjfw8djVygvDpTncA0NO2MDY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75027	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1236950|uniprotkb:O75345|uniprotkb:Q5VWY7|uniprotkb:Q5VWY8|uniprotkb:Q9BRE1|uniprotkb:Q9UND1|uniprotkb:Q9UP01|uniprotkb:G3XAC4|ensembl:ENSP00000362492	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:abcb7_human(display_long)|uniprotkb:ABCB7(gene name)|psi-mi:ABCB7(display_short)|uniprotkb:ABC7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001258626.1|ensembl:ENSG00000131269(gene)|ensembl:ENST00000373394(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:O75027|reactome:R-HSA-1369007|reactome:R-HSA-2564830|refseq:NP_004290.2|refseq:NP_001258625.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:nsOzSS/enZTkOfd1nRlk8Wv4KRM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P13196	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3905054|ensembl:ENSP00000309259|ensembl:ENSP00000378416|ensembl:ENSP00000417719|ensembl:ENSP00000418779	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hem1_human(display_long)|uniprotkb:ALAS1(gene name)|psi-mi:ALAS1(display_short)|uniprotkb:ALAS3(gene name synonym)|uniprotkb:ALASH(gene name synonym)|uniprotkb:5-aminolevulinic acid synthase 1(gene name synonym)|uniprotkb:Delta-ALA synthase 1(gene name synonym)|uniprotkb:Delta-aminolevulinate synthase 1(gene name synonym)|uniprotkb:OK/SW-cl.121(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001291372.1|refseq:NP_001291373.1|refseq:NP_000679.1|refseq:NP_954635.1|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0048821"(erythrocyte development)|ensembl:ENSG00000023330(gene)|ensembl:ENST00000310271(transcript)|ensembl:ENST00000394965(transcript)|ensembl:ENST00000469224(transcript)|ensembl:ENST00000484952(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003870"(5-aminolevulinate synthase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR010961(Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase)|interpro:IPR015118(5-aminolevulinate synthase presequence)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P13196|reactome:R-HSA-189451|reactome:R-HSA-1989781|reactome:R-HSA-2151201|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:HFjJ6zrRF9UYD7LMB6A3CcxcS7c9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P30519	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-712096|uniprotkb:I3L430|ensembl:ENSP00000219700|ensembl:ENSP00000381595|ensembl:ENSP00000385100|ensembl:ENSP00000391637|ensembl:ENSP00000394103|ensembl:ENSP00000459214|ensembl:ENSP00000478785|ensembl:ENSP00000481295|ensembl:ENSP00000481811|ensembl:ENSP00000483319|ensembl:ENSP00000484422|ensembl:ENSP00000484423|ensembl:ENSP00000484467|ensembl:ENSP00000487673|ensembl:ENSP00000488579|ensembl:ENSP00000488880|uniprotkb:O60605|uniprotkb:A8MT35|uniprotkb:D3DUD5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hmox2_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)|uniprotkb:HO2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001273196.1|refseq:NP_001273197.1|refseq:NP_001273198.1|refseq:NP_001273199.1|refseq:NP_001273200.1|ensembl:ENSG00000103415(gene)|ensembl:ENSG00000277424(gene)|ensembl:ENST00000219700(transcript)|ensembl:ENST00000398595(transcript)|ensembl:ENST00000406590(transcript)|ensembl:ENST00000414777(transcript)|ensembl:ENST00000458134(transcript)|ensembl:ENST00000570646(transcript)|ensembl:ENST00000612525(transcript)|ensembl:ENST00000615778(transcript)|ensembl:ENST00000619528(transcript)|ensembl:ENST00000619913(transcript)|ensembl:ENST00000620445(transcript)|ensembl:ENST00000621065(transcript)|ensembl:ENST00000622146(transcript)|ensembl:ENST00000631540(transcript)|ensembl:ENST00000631677(transcript)|ensembl:ENST00000632458(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006788"(heme oxidation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042167"(heme catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|rcsb pdb:4WMH|rcsb pdb:5UC8|rcsb pdb:5UC9|rcsb pdb:5UCA|reactome:R-HSA-189483|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-917937|reactome:R-HSA-9707564|mint:P30519|rcsb pdb:2Q32|rcsb pdb:2QPP|rcsb pdb:2RGZ|refseq:NP_001120676.1|refseq:NP_001120677.1|refseq:NP_001120678.1|refseq:NP_002125.3|refseq:XP_016878685.1|refseq:XP_016878686.1|dip:DIP-53564N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:yTwXdEjnQgfiFBvl5fhcCwDOJWo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:A2RTX5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1056629|uniprotkb:Q6B0A1|uniprotkb:Q6IS76|uniprotkb:Q96LW3|uniprotkb:Q96MP4|uniprotkb:B2RMP7|ensembl:ENSP00000338093	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sytc2_human(display_long)|uniprotkb:TARS3(gene name)|psi-mi:TARS3(display_short)|uniprotkb:TARSL2(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_689547.2|ensembl:ENSG00000185418(gene)|ensembl:ENST00000335968(transcript)|go:"GO:0004829"(threonine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006435"(threonyl-tRNA aminoacylation)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004095(TGS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018163|interpro:IPR033728|interpro:IPR036621|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5qtWTeLjIRJlr0xyMo7LeP8wbzw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P49590	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3909030|uniprotkb:B4DDY8|intact:EBI-10988212|ensembl:ENSP00000230771|ensembl:ENSP00000494296	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:syhm_human(display_long)|uniprotkb:Histidyl-tRNA synthetase(gene name synonym)|uniprotkb:HARS2(gene name)|psi-mi:HARS2(display_short)|uniprotkb:HARSL(gene name synonym)|uniprotkb:HARSR(gene name synonym)|uniprotkb:HO3(gene name synonym)|uniprotkb:Histidine--tRNA ligase-like(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_036340.1|refseq:NP_001265660.1|refseq:NP_001265661.1|ensembl:ENSG00000112855(gene)|ensembl:ENST00000230771(transcript)|ensembl:ENST00000645749(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004821"(histidine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006427"(histidyl-tRNA aminoacylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004516(Histidyl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR015807(Histidyl-tRNA synthetase, class IIa, subgroup)|interpro:IPR033656|interpro:IPR036621|interpro:IPR041715|reactome:R-HSA-379726|go:"GO:0006412"(translation)|dip:DIP-59626N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:pp4g+OJKxW3va88iXtfIAnGXMKw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96I59	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-5455236|uniprotkb:G3V178|ensembl:ENSP00000281038	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:synm_human(display_long)|uniprotkb:NARS2(gene name)|psi-mi:NARS2(display_short)|uniprotkb:Asparaginyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_078954.4|refseq:NP_001230180.1|refseq:XP_016873792.1|ensembl:ENSG00000137513(gene)|ensembl:ENST00000281038(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004816"(asparagine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006421"(asparaginyl-tRNA aminoacylation)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004522(Asparaginyl-tRNA synthetase, class IIb)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-HSA-379726	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8r61DYTijthPntztWKOxzbklcPY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96GW9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943412|ensembl:ENSP00000282276|uniprotkb:A0AVC3|uniprotkb:Q76E79|uniprotkb:Q8IW62|uniprotkb:Q8N7N4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:symm_human(display_long)|uniprotkb:MARS2(gene name)|psi-mi:MARS2(display_short)|uniprotkb:Methionyl-tRNA synthetase 2(gene name synonym)|uniprotkb:Mitochondrial methionyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000247626(gene)|ensembl:ENST00000282276(transcript)|go:"GO:0004825"(methionine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006431"(methionyl-tRNA aminoacylation)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014758(Methionyl-tRNA synthetase, class Ia, N-terminal)|interpro:IPR015413("Aminoacyl-tRNA synthetase, class I (M)")|interpro:IPR033911|interpro:IPR041872|reactome:R-HSA-379726|refseq:NP_612404.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:szIF1rHzaKztwl8mdFzv7bbCSQI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95363	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2513774|ensembl:ENSP00000274680|ensembl:ENSP00000316335|uniprotkb:B2R664|uniprotkb:Q6FG29|uniprotkb:Q9NPY7|uniprotkb:Q9P062|uniprotkb:Q53F66|uniprotkb:Q5TCS3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:syfm_human(display_long)|uniprotkb:FARS2(gene name)|psi-mi:FARS2(display_short)|uniprotkb:FARS1(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase(gene name synonym)|uniprotkb:HSPC320(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000145982(gene)|ensembl:ENST00000274680(transcript)|ensembl:ENST00000324331(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004530(Phenylalanyl-tRNA synthetase, class IIc, mitochondrial)|interpro:IPR005121(Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036690|rcsb pdb:3CMQ|rcsb pdb:3HFV|rcsb pdb:3TEG|rcsb pdb:3TUP|rcsb pdb:5MGH|rcsb pdb:5MGU|rcsb pdb:5MGV|rcsb pdb:5MGW|reactome:R-HSA-379726|refseq:NP_001305801.1|refseq:NP_006558.1|refseq:XP_016865675.1|refseq:XP_016865676.1|refseq:XP_005248869.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bClmsDMPN2mEiOKnN8nuhlWpwQc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5JPH6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943410|ensembl:ENSP00000395196|ensembl:ENSP00000501251|uniprotkb:B3KTT2|uniprotkb:D3DWF1|uniprotkb:Q86YH3|uniprotkb:Q8TF31	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:syem_human(display_long)|uniprotkb:EARS2(gene name)|psi-mi:EARS2(display_short)|uniprotkb:Glutamyl-tRNA synthetase(gene name synonym)|uniprotkb:KIAA1970(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	interpro:IPR008925(Aminoacyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020058|interpro:IPR020751|interpro:IPR033910|reactome:R-HSA-379726|ensembl:ENSG00000103356(gene)|ensembl:ENST00000449606(transcript)|ensembl:ENST00000674054(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0050561"("glutamate-tRNA(Gln) ligase activity")|go:"GO:0070127"(tRNA aminoacylation for mitochondrial protein translation)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004527(Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial)|refseq:NP_001077083.1|refseq:NP_001295140.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Jo4TXXabhrL7bgEVz1Ffm/766PA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UGM6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10897254|uniprotkb:B1ALR1|uniprotkb:B2R9D4|uniprotkb:Q53FT4|uniprotkb:Q5VUD2|uniprotkb:Q86TQ0|ensembl:ENSP00000235521	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sywm_human(display_long)|uniprotkb:WARS2(gene name)|psi-mi:WARS2(display_short)|uniprotkb:"(Mt)TrpRS"(gene name synonym)|uniprotkb:Tryptophanyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_056651.1|refseq:NP_957715.1|ensembl:ENSG00000116874(gene)|ensembl:ENST00000235521(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0004830"(tryptophan-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006436"(tryptophanyl-tRNA aminoacylation)|go:"GO:0070183"(mitochondrial tryptophanyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002306(Tryptophanyl-tRNA synthetase, class Ib)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR024109|rcsb pdb:5EKD|reactome:R-HSA-379726	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:a3ec+kKKGh4XiLJcUoBdk3B2uFs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NP81	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1049768|uniprotkb:A6NHW7|uniprotkb:Q9BVP3|uniprotkb:B4DE10|ensembl:ENSP00000221431|ensembl:ENSP00000489539	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sysm_human(display_long)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)|uniprotkb:SerRSmt(gene name synonym)|uniprotkb:SARS2(gene name)|psi-mi:SARS2(display_short)|uniprotkb:SARSM(gene name synonym)|uniprotkb:Seryl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001139373.1|refseq:NP_060297.1|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR033729|interpro:IPR042103|mint:Q9NP81|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|reactome:R-HSA-379726|ensembl:ENSG00000104835(gene)|ensembl:ENSG00000283104(gene)|ensembl:ENST00000221431(transcript)|ensembl:ENST00000634687(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0070158"(mitochondrial seryl-tRNA aminoacylation)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xYa2ZQIifKicNHV/6vlcUGaN9q49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q7L3T8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3184163|ensembl:ENSP00000360327|uniprotkb:Q9H6S5|uniprotkb:A8K0W4|uniprotkb:Q9UFT1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sypm_human(display_long)|uniprotkb:PARS2(gene name)|psi-mi:PARS2(display_short)|uniprotkb:Prolyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000162396(gene)|ensembl:ENST00000371279(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002316(Prolyl-tRNA synthetase, class IIa)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR033730|interpro:IPR036621|reactome:R-HSA-379726|refseq:NP_689481.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:KdT2n/JLc/MA/qtzzQP0tusMX489606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15031	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943408|ensembl:ENSP00000495093|ensembl:ENSP00000495707|ensembl:ENSP00000498867	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sylm_human(display_long)|uniprotkb:LARS2(gene name)|psi-mi:LARS2(display_short)|uniprotkb:KIAA0028(gene name synonym)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-HSA-379726|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002302(Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|ensembl:ENST00000642274(transcript)|ensembl:ENST00000645846(transcript)|ensembl:ENST00000650792(transcript)|ensembl:ENSG00000011376(gene)|refseq:NP_056155.1|refseq:XP_005265063.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9yihm8Ai9McATYK+d12UMtP6A6k9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6PI48	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3917045|ensembl:ENSP00000497569	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sydm_human(display_long)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:DARS2(gene name)|psi-mi:DARS2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060592.2|ensembl:ENSG00000117593(gene)|ensembl:ENST00000649689(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043039"(tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|go:"GO:0070145"(mitochondrial asparaginyl-tRNA aminoacylation)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR029351|rcsb pdb:4AH6|reactome:R-HSA-379726|go:"GO:0005759"(mitochondrial matrix)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:6tNhPqrlJ5dCXoDIgUjcUB/gA7s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NSE4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BW92	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1045099|uniprotkb:Q53GW7|uniprotkb:Q96I50|ensembl:ENSP00000358060|uniprotkb:Q9H9V2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sytm_human(display_long)|uniprotkb:Threonyl-tRNA synthetase-like 1(gene name synonym)|uniprotkb:TARS2(gene name)|psi-mi:TARS2(display_short)|uniprotkb:TARSL1(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_079426.2|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)|interpro:IPR004095(TGS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018163|interpro:IPR033728|interpro:IPR036621|reactome:R-HSA-379726|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|ensembl:ENSG00000143374(gene)|ensembl:ENST00000369064(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004829"(threonine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006435"(threonyl-tRNA aminoacylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070159"(mitochondrial threonyl-tRNA aminoacylation)|refseq:NP_001258825.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9osvUit1PmESv7edUxgA1cl3o/Y9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5JTZ9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-308736|uniprotkb:Q8N198|uniprotkb:Q96D02|uniprotkb:Q9ULF0|uniprotkb:A2RRN5|ensembl:ENSP00000244571	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:syam_human(display_long)|uniprotkb:KIAA1270(gene name synonym)|uniprotkb:AARS2(gene name)|psi-mi:AARS2(display_short)|uniprotkb:AARSL(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_065796.1|ensembl:ENSG00000124608(gene)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:Q5JTZ9|rcsb pdb:6NLQ|rcsb pdb:6NLY|rcsb pdb:6NOW|reactome:R-HSA-379726|ensembl:ENST00000244571(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006400"(tRNA modification)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0070143"(mitochondrial alanyl-tRNA aminoacylation)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RzNZMsaNjWpD4eB5AdgpjhC3vP09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y2Z4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1049286|uniprotkb:Q9H817|uniprotkb:D3DUW8|ensembl:ENSP00000320658	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:syym_human(display_long)|uniprotkb:YARS2(gene name)|psi-mi:YARS2(display_short)|uniprotkb:Tyrosyl-tRNA synthetase(gene name synonym)|uniprotkb:CGI-04(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001035526.1|ensembl:ENSG00000139131(gene)|ensembl:ENST00000324868(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004831"(tyrosine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016604"(nuclear body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043039"(tRNA aminoacylation)|go:"GO:0070184"(mitochondrial tyrosyl-tRNA aminoacylation)|go:"GO:0072545"(tyrosine binding)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002307(Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR024088|interpro:IPR036986|rcsb pdb:2PID|rcsb pdb:3ZXI|reactome:R-HSA-379726|dip:DIP-29487N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:cTNOZVenqyzWUlHTF7XLcZIKV+s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y606	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-4399438|uniprotkb:A8K877|uniprotkb:B3KQC1|uniprotkb:Q8WYT2|uniprotkb:Q9BU44|ensembl:ENSP00000365837	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:trua_human(display_long)|uniprotkb:PP8985(orf name)|uniprotkb:PUS1(gene name)|psi-mi:PUS1(display_short)|uniprotkb:"tRNA pseudouridine(38-40) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase I(gene name synonym)|uniprotkb:tRNA-uridine isomerase I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001002019.1|refseq:NP_001002020.1|refseq:NP_079491.2|ensembl:ENSG00000177192(gene)|ensembl:ENST00000376649(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002153"(steroid receptor RNA activator RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0070902"(mitochondrial tRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR020094|interpro:IPR020095|interpro:IPR020097|interpro:IPR020103|interpro:IPR041708|rcsb pdb:4IQM|rcsb pdb:4ITS|rcsb pdb:4J37|rcsb pdb:4NZ6|rcsb pdb:4NZ7|reactome:R-HSA-6782315|reactome:R-HSA-6787450|interpro:IPR001406(tRNA pseudouridine synthase)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/FqnystQZg3oW8+k5h55079sOFM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q00059	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P54727	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-954531|uniprotkb:Q8WUB0|uniprotkb:B3KWK8|ensembl:ENSP00000350708|uniprotkb:G5E9P0|uniprotkb:Q7Z5K8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rd23b_human(display_long)|uniprotkb:XP-C repair-complementing complex 58 kDa protein(gene name synonym)|uniprotkb:RAD23B(gene name)|psi-mi:RAD23B(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002865.1|refseq:NP_001231653.1|ensembl:ENSG00000119318(gene)|ensembl:ENST00000358015(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR036353|interpro:IPR041811|mint:P54727|rcsb pdb:1P1A|rcsb pdb:1PVE|rcsb pdb:1UEL|reactome:R-HSA-532668|reactome:R-HSA-5689877|reactome:R-HSA-5696394|reactome:R-HSA-5696395|interpro:IPR029071|dip:DIP-39944N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:msyh4+G2TzDW+xgGjixPKWWrjRE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H0S4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2515241|ensembl:ENSP00000350698|uniprotkb:Q96NV8|uniprotkb:B3KXP4|uniprotkb:Q96GM0|uniprotkb:G5E955|uniprotkb:Q9UI98	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx47_human(display_long)|uniprotkb:DDX47(gene name)|psi-mi:DDX47(display_short)|uniprotkb:DEAD box protein 47(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000213782(gene)|ensembl:ENST00000358007(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044765|mint:Q9H0S4|rcsb pdb:3BER|reactome:R-HSA-6790901|reactome:R-HSA-6791226|interpro:IPR014001(DEAD-like helicase, N-terminal)|refseq:NP_057439.2|refseq:NP_957518.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:AhH5kg/8cw6L5385wUw4PR243rY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UJV9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1046350|ensembl:ENSP00000330349|uniprotkb:Q96BK6|uniprotkb:Q96K05|uniprotkb:Q9NT96|uniprotkb:Q9NW04|uniprotkb:B2RDC8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx41_human(display_long)|uniprotkb:DEAD box protein 41(gene name synonym)|uniprotkb:DEAD box protein abstrakt homolog(gene name synonym)|uniprotkb:DDX41(gene name)|psi-mi:DDX41(display_short)|uniprotkb:ABS(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000183258(gene)|ensembl:ENST00000330503(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044113|mint:Q9UJV9|rcsb pdb:2P6N|rcsb pdb:5GVS|rcsb pdb:5H1Y|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-3270619|rcsb pdb:5GVR|refseq:NP_057306.2|refseq:NP_001308661.1|refseq:NP_001308759.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:a3HNDsQBaXs/1q8ZXjkcMgEhPes9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q13838	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00148	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NUL7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2560229|ensembl:ENSP00000332340	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx28_human(display_long)|uniprotkb:DDX28(gene name)|psi-mi:DDX28(display_short)|uniprotkb:MDDX28(gene name synonym)|uniprotkb:Mitochondrial DEAD box protein 28(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060850.2|ensembl:ENSG00000182810(gene)|ensembl:ENST00000332395(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:aq2jUV+jvcoBIROUedWr86FxEl89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9GZR7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NR30	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UHI6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NUU7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-740301|uniprotkb:Q53FM0|uniprotkb:B2RPL0|uniprotkb:B4DRZ7|ensembl:ENSP00000306117	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dd19a_human(display_long)|uniprotkb:DEAD box protein 19A(gene name synonym)|uniprotkb:DDX19-like protein(gene name synonym)|uniprotkb:DDX19A(gene name)|psi-mi:DDX19A(display_short)|uniprotkb:DDX19L(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060802.1|ensembl:ENSG00000168872(gene)|ensembl:ENST00000302243(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|refseq:NP_001307451.1|refseq:NP_001307454.1|refseq:NP_001307455.1|refseq:NP_001307456.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Uvjex/lODTGHjNguDqyaquwkNaw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NVP1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-724378|ensembl:ENSP00000263239|uniprotkb:Q6GTZ9|uniprotkb:Q6IAU4|uniprotkb:Q92732|uniprotkb:Q9BQB7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx18_human(display_long)|uniprotkb:DEAD box protein 18(gene name synonym)|uniprotkb:Myc-regulated DEAD box protein(gene name synonym)|uniprotkb:DDX18(gene name)|psi-mi:DDX18(display_short)|uniprotkb:cPERP-D(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006764.3|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025313|interpro:IPR027417|interpro:IPR044773|mint:Q9NVP1|rcsb pdb:3LY5|ensembl:ENSG00000088205(gene)|ensembl:ENST00000263239(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0071392"(cellular response to estradiol stimulus)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RmupZbt33/w1V7Uq5vnRO36j2Tc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92841	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P17844	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15523	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2462220|uniprotkb:Q8IYV7|uniprotkb:B4DK29|uniprotkb:B4DXX7|ensembl:ENSP00000336725|ensembl:ENSP00000353284	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx3y_human(display_long)|uniprotkb:DDX3Y(gene name)|psi-mi:DDX3Y(display_short)|uniprotkb:DBY(gene name synonym)|uniprotkb:DEAD box protein 3, Y-chromosomal(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001116137.1|refseq:NP_004651.2|refseq:NP_001289481.1|ensembl:ENSG00000067048(gene)|ensembl:ENST00000336079(transcript)|ensembl:ENST00000360160(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007276"(gamete generation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O15523	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:dYhBr9Igq5eMq9U8g+c30nfdaKo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00571	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q92499	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-358474|ensembl:ENSP00000233084|ensembl:ENSP00000370745|ensembl:ENSP00000413767|ensembl:ENSP00000504080|uniprotkb:B4DME8|uniprotkb:B4DPN6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ddx1_human(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:DEAD box protein retinoblastoma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000079785(gene)|ensembl:ENST00000233084(transcript)|ensembl:ENST00000381341(transcript)|ensembl:ENST00000434671(transcript)|ensembl:ENST00000677302(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|refseq:NP_004930.1|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071920"(cleavage body)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR043136|mint:Q92499|rcsb pdb:4XW3|reactome:R-HSA-6784531|dip:DIP-38163N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:n2Zv07BpuUDT32/ttDzIFXH3yIQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P49643	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-850004|uniprotkb:Q53FJ8|uniprotkb:Q6P1Q7|uniprotkb:Q8WVL2|uniprotkb:Q9H413|ensembl:ENSP00000484105	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pri2_human(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:PRIM2(gene name)|psi-mi:PRIM2(display_short)|uniprotkb:PRIM2A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001269416.1|refseq:NP_001269417.1|refseq:NP_000938.2|dip:DIP-36438N|ensembl:ENSG00000146143(gene)|ensembl:ENST00000615550(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|mint:P49643|rcsb pdb:3L9Q|rcsb pdb:3Q36|rcsb pdb:4BPU|rcsb pdb:4BPW|rcsb pdb:4BPX|rcsb pdb:4RR2|rcsb pdb:5DQO|rcsb pdb:5EXR|rcsb pdb:5F0Q|rcsb pdb:5F0S|rcsb pdb:5I7M|rcsb pdb:6DHW|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-9710421	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:WL5i+CvK52C93/3X4a3MFQvD0JQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P19387	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P49005	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-372354|ensembl:ENSP00000386105|ensembl:ENSP00000395231|ensembl:ENSP00000480186|uniprotkb:A4D2J4|uniprotkb:B2R5S4	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dpod2_human(display_long)|uniprotkb:POLD2(gene name)|psi-mi:POLD2(display_short)|uniprotkb:DNA polymerase delta subunit p50(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001120690.1|ensembl:ENSG00000106628(gene)|ensembl:ENST00000406581(transcript)|ensembl:ENST00000452185(transcript)|ensembl:ENST00000610533(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863|mint:P49005|rcsb pdb:3E0J|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|refseq:NP_001243808.1|refseq:NP_006221.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:B8QUTohwg0iz3s5wdSdmcTGa28I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q15054	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-864956|uniprotkb:B7ZAI6|uniprotkb:Q32MZ9|uniprotkb:Q32N00|ensembl:ENSP00000263681	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dpod3_human(display_long)|uniprotkb:DNA polymerase delta subunit p66(gene name synonym)|uniprotkb:POLD3(gene name)|psi-mi:POLD3(display_short)|uniprotkb:KIAA0039(gene name synonym)|uniprotkb:DNA polymerase delta subunit C(gene name synonym)|uniprotkb:DNA polymerase delta subunit p68(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006582.1|dip:DIP-35772N|ensembl:ENSG00000077514(gene)|ensembl:ENST00000263681(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|interpro:IPR019038|interpro:IPR041913|mint:Q15054|rcsb pdb:1U76|rcsb pdb:2N1G|rcsb pdb:3E0J|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:lqGl+fKC1gasYIgeCvroW9DTKBg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P19388	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O15160	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1055079|uniprotkb:O75395|uniprotkb:Q5JTE3|ensembl:ENSP00000496044	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:rpac1_human(display_long)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPC40(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001305805.1|refseq:NP_976035.1|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|mint:O15160|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-27587N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P28340	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-716569|uniprotkb:Q8NER3|uniprotkb:Q96H98|ensembl:ENSP00000406046|ensembl:ENSP00000472600|ensembl:ENSP00000473052	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dpod1_human(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase subunit delta p125(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short)|uniprotkb:POLD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002682.2|refseq:XP_011525340.1|refseq:NP_001243778.1|ensembl:ENSG00000062822(gene)|ensembl:ENST00000599857(transcript)|ensembl:ENST00000601098(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0009411"(response to UV)|ensembl:ENST00000440232(transcript)|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-5358606|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019899"(enzyme binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|mint:P28340|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-2564830|reactome:R-HSA-5358565|refseq:XP_016882370.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bJ5Q0xOzHga/zxMOBHkuXaFXeLw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8WXE1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-747353|uniprotkb:Q8NHQ2|uniprotkb:Q8WUG7|uniprotkb:Q96CL3|uniprotkb:Q9HA30|uniprotkb:A8K6A3|uniprotkb:A8K714|uniprotkb:B2RCE7|uniprotkb:Q69YK9|uniprotkb:B4DU92|uniprotkb:B5MEB7|ensembl:ENSP00000323099	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:atrip_human(display_long)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_115542.2|refseq:NP_569055.1|dip:DIP-46495N|refseq:NP_001257951.1|refseq:NP_001257952.1|ensembl:ENSG00000164053(gene)|ensembl:ENST00000320211(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR033349|mint:Q8WXE1|rcsb pdb:4IGK|rcsb pdb:4NB3|rcsb pdb:5YZ0|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-69473	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VVllxHySIT6EGlT6SQhPePAXbsI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P13804	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1052886|uniprotkb:B4DT43|uniprotkb:Q53XN3|ensembl:ENSP00000452762	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:etfa_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000117.1|refseq:NP_001121188.1|dip:DIP-6161N|ensembl:ENSG00000140374(gene)|ensembl:ENST00000557943(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947|mint:P13804|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:J2PUTTVN+nd8eHe6TXga+37CiPw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P23526	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1053240|uniprotkb:Q96A36|ensembl:ENSP00000217426|uniprotkb:B3KUN3|uniprotkb:F5H737|uniprotkb:A8K307|uniprotkb:E1P5P2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sahh_human(display_long)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:AHCY(gene name)|psi-mi:AHCY(display_short)|uniprotkb:SAHH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000678.1|refseq:NP_001155238.1|ensembl:ENSG00000101444(gene)|ensembl:ENST00000217426(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002439"(chronic inflammatory response to antigenic stimulus)|go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0019510"(S-adenosylhomocysteine catabolic process)|go:"GO:0030554"(adenyl nucleotide binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042470"(melanosome)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:P23526|rcsb pdb:1A7A|rcsb pdb:1LI4|refseq:XP_011526961.1|refseq:XP_005260374.1|refseq:NP_001309013.1|refseq:NP_001309014.1|rcsb pdb:3NJ4|rcsb pdb:4PFJ|rcsb pdb:4PGF|rcsb pdb:4YVF|rcsb pdb:5W49|rcsb pdb:5W4B|reactome:R-HSA-156581|reactome:R-HSA-1614635|reactome:R-HSA-2408508|reactome:R-HSA-5578997|refseq:XP_016883197.1|refseq:XP_016883198.1|dip:DIP-50557N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+y7rwgw9EIMaVrkt4/9kbZM44sg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TCS8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1052020|uniprotkb:Q53SU0|uniprotkb:Q68CN1|uniprotkb:Q7Z7D1|uniprotkb:Q8IWX1|uniprotkb:Q96T05|uniprotkb:Q9BRU3|uniprotkb:Q9BVX0|ensembl:ENSP00000393953|ensembl:ENSP00000400646	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:pnpt1_human(display_long)|uniprotkb:Polynucleotide phosphorylase 1(gene name synonym)|uniprotkb:Polynucleotide phosphorylase-like protein(gene name synonym)|uniprotkb:PNPase old-35(gene name synonym)|uniprotkb:3'-5' RNA exonuclease OLD35(gene name synonym)|uniprotkb:PNPT1(gene name)|psi-mi:PNPT1(display_short)|uniprotkb:PNPASE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_149100.2|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|go:"GO:0097222"(mitochondrial mRNA polyadenylation)|go:"GO:0097421"(liver regeneration)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR003029(S1, RNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012162(Polyribonucleotide nucleotidyltransferase)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR015848(Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type)|interpro:IPR020568|interpro:IPR022967|interpro:IPR027408|interpro:IPR036345|interpro:IPR036456|interpro:IPR036612|rcsb pdb:3U1K|rcsb pdb:5ZF6|ensembl:ENSG00000138035(gene)|ensembl:ENST00000415374(transcript)|ensembl:ENST00000447944(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000957"(mitochondrial RNA catabolic process)|go:"GO:0000958"(mitochondrial mRNA catabolic process)|go:"GO:0000962"(positive regulation of mitochondrial RNA catabolic process)|go:"GO:0000964"(mitochondrial RNA 5'-end processing)|go:"GO:0000965"(mitochondrial RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0034046"("poly(G) binding")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035927"(RNA import into mitochondrion)|go:"GO:0035928"(rRNA import into mitochondrion)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0045025"(mitochondrial degradosome)|go:"GO:0004654"(polyribonucleotide nucleotidyltransferase activity)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060416"(response to growth hormone)|dip:DIP-50226N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:W9hr1vfWv1b0v4xfMYatfKfOMcg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00330	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-751566|uniprotkb:O60221|uniprotkb:Q96FV8|uniprotkb:Q99783|uniprotkb:D3DR11|uniprotkb:E9PB14|uniprotkb:B4DW62|uniprotkb:E9PBP7|ensembl:ENSP00000227868	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:odpx_human(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Lipoyl-containing pyruvate dehydrogenase complex component X(gene name synonym)|uniprotkb:E3-binding protein(gene name synonym)|uniprotkb:proX(gene name synonym)|uniprotkb:PDHX(gene name)|psi-mi:PDHX(display_short)|uniprotkb:PDX1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001128496.1|refseq:NP_001159630.1|refseq:NP_003468.2|dip:DIP-29026N|ensembl:ENSG00000110435(gene)|ensembl:ENST00000227868(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:O00330|rcsb pdb:1ZY8|rcsb pdb:2DNC|rcsb pdb:2F5Z|rcsb pdb:2F60|rcsb pdb:6H60|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-70268	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fcQCBKmyySLi0lr+SQKUkPy+rwE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P53597	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1237145|uniprotkb:Q9BWB0|uniprotkb:Q9UNP6|ensembl:ENSP00000377446	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:suca_human(display_long)|uniprotkb:SUCLG1(gene name)|psi-mi:SUCLG1(display_short)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003840.2|ensembl:ENSG00000163541(gene)|ensembl:ENST00000393868(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR033847|interpro:IPR036291|mint:P53597|rcsb pdb:6G4Q|rcsb pdb:6WCV|reactome:R-HSA-71403	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fti5qbvs9ndhRyZyoPEuTxMpEgo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9P2R7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96I99	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2511878|ensembl:ENSP00000307432|uniprotkb:Q8WUQ1|uniprotkb:Q86VX8|uniprotkb:O95195|uniprotkb:Q6NUH7|uniprotkb:C9JVT2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sucb2_human(display_long)|uniprotkb:SUCLG2(gene name)|psi-mi:SUCLG2(display_short)|uniprotkb:GTP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-G chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000172340(gene)|ensembl:ENST00000307227(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034722|mint:Q96I99|rcsb pdb:6WCV|reactome:R-HSA-71403|refseq:NP_001171070.1|refseq:NP_003839.2|dip:DIP-53563N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:jxrFGuu3hFn2QAYfrPxTKhScM249606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P07814	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-355315|uniprotkb:Q5H9S5|uniprotkb:Q6PD57|uniprotkb:Q86X73|uniprotkb:A0AVA9|uniprotkb:Q05BP6|uniprotkb:Q05DF8|uniprotkb:Q5DSM1|ensembl:ENSP00000355890|uniprotkb:B9EGH3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:syep_human(display_long)|uniprotkb:EPRS1(gene name)|psi-mi:EPRS1(display_short)|uniprotkb:Bifunctional aminoacyl-tRNA synthetase(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 32 protein(gene name synonym)|uniprotkb:EPRS(gene name synonym)|uniprotkb:GLNS(gene name synonym)|uniprotkb:Glutamatyl-prolyl-tRNA synthetase(gene name synonym)|uniprotkb:PARS(gene name synonym)|uniprotkb:QARS(gene name synonym)|uniprotkb:QPRS(gene name synonym)|uniprotkb:PIG32(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004437.2|ensembl:ENSG00000136628(gene)|ensembl:ENST00000366923(transcript)|go:"GO:0004818"(glutamate-tRNA ligase activity)|go:"GO:0004827"(proline-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006424"(glutamyl-tRNA aminoacylation)|go:"GO:0006433"(prolyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051020"(GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0140212"(regulation of long-chain fatty acid import into cell)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000738(WHEP-TRS)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR004154(Anticodon-binding)|interpro:IPR004499(Prolyl-tRNA synthetase, class IIa, prokaryotic-type)|interpro:IPR004526(Glutamyl-tRNA synthetase, class Ic, archaeal/eukaryotic cytosolic)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR016061(Prolyl-tRNA synthetase, class II, C-terminal)|interpro:IPR017449(Prolyl-tRNA synthetase, class II)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR033721|interpro:IPR036282|interpro:IPR036621|mint:P07814|rcsb pdb:1FYJ|rcsb pdb:4HVC|rcsb pdb:4K86|rcsb pdb:4K87|rcsb pdb:4K88|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5BMU|rcsb pdb:5V58|rcsb pdb:5VAD|rcsb pdb:5Y6L|rcsb pdb:6IY6|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-6782315|dip:DIP-40825N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:67nL6JkhNTSttOucQt3mLRQZeLY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O60884	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q0VDF9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-8773684|uniprotkb:A8K8F8|uniprotkb:B0YIY9|uniprotkb:Q9P0X2|uniprotkb:Q9UI07|ensembl:ENSP00000367623	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hsp7e_human(display_long)|uniprotkb:HSPA14(gene name)|psi-mi:HSPA14(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:HSP70L1(gene name synonym)|uniprotkb:HSP70-like protein 1(gene name synonym)|uniprotkb:Heat shock protein HSP60(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057383.2|ensembl:ENSG00000187522(gene)|ensembl:ENST00000378372(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR042049|interpro:IPR043129|mint:Q0VDF9|reactome:R-HSA-3371453|dip:DIP-62114N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RNKKz93Uww+GkRXdvnm5QY8h+lM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HAV7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TAA5	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943406|ensembl:ENSP00000329558|uniprotkb:B4DFA6|uniprotkb:Q49AJ6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:grpe2_human(display_long)|uniprotkb:GRPEL2(gene name)|psi-mi:GRPEL2(display_short)|uniprotkb:Mt-GrpE#2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000164284(gene)|ensembl:ENST00000329271(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|reactome:R-HSA-1268020|refseq:NP_689620.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Lasb9LN0fF/paO9BJ/7IhS27rhM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y5Y2	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1048886|uniprotkb:Q9NWB2|uniprotkb:D3DU80|ensembl:ENSP00000262302	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nubp2_human(display_long)|uniprotkb:Nucleotide-binding protein 2(gene name synonym)|uniprotkb:NUBP2(gene name)|psi-mi:NUBP2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001271430.1|refseq:NP_036357.1|ensembl:ENSG00000095906(gene)|ensembl:ENST00000262302(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030030"(cell projection organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000808(Mrp, conserved site)|interpro:IPR019591|interpro:IPR027417|interpro:IPR028600|interpro:IPR033756|mint:Q9Y5Y2|reactome:R-HSA-2564830	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DKKt1Lpqk/vwGbwhYDXv3Bgtqdc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y3D0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-744045|ensembl:ENSP00000387471	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P18074	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-6380590|ensembl:ENSP00000375809|ensembl:ENSP00000507019|uniprotkb:Q2TB78|uniprotkb:Q2YDY2|uniprotkb:Q7KZU6|uniprotkb:Q8N721	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ercc2_human(display_long)|uniprotkb:ERCC2(gene name)|psi-mi:ERCC2(display_short)|uniprotkb:XPD(gene name synonym)|uniprotkb:XPDC(gene name synonym)|uniprotkb:Basic transcription factor 2 80 kDa subunit(gene name synonym)|uniprotkb:CXPD(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-2(gene name synonym)|uniprotkb:DNA repair protein complementing XP-D cells(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex 80 kDa subunit(gene name synonym)|uniprotkb:Xeroderma pigmentosum group D-complementing protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000104884(gene)|ensembl:ENST00000391945(transcript)|ensembl:ENST00000682414(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021510"(spinal cord development)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045951"(positive regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0071817"(MMXD complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR001945(Xeroderma pigmentosum group D protein)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR010643(Protein of unknown function DUF1227)|go:"GO:0006915"(apoptotic process)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|mint:P18074|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:6TUN|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-2564830|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|dip:DIP-644N|refseq:NP_000391.1|refseq:NP_001124339.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:zZKINZxsFZY4rkmg9VNqc4rTTjQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NZ45	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1050885|intact:EBI-2803159|uniprotkb:Q1X902|ensembl:ENSP00000363041	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cisd1_human(display_long)|uniprotkb:C10orf70(gene name synonym)|uniprotkb:CISD1(gene name)|psi-mi:CISD1(display_short)|uniprotkb:ZCD1(gene name synonym)|uniprotkb:MitoNEET(gene name synonym)|uniprotkb:MDS029(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060934.1|ensembl:ENSG00000122873(gene)|ensembl:ENST00000333926(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR018967|interpro:IPR019610|interpro:IPR042216|mint:Q9NZ45|rcsb pdb:2QD0|rcsb pdb:2QH7|rcsb pdb:2R13|rcsb pdb:3EW0|rcsb pdb:3LPQ|rcsb pdb:3REE|rcsb pdb:4EZF|rcsb pdb:4F1E|rcsb pdb:4F28|rcsb pdb:4F2C|rcsb pdb:6DE9|dip:DIP-46446N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:mrkU9Txm3hkC1rWqrPob5k7wJ3g9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P61221	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2510446|ensembl:ENSP00000296577|uniprotkb:Q6NR76|uniprotkb:O88793|uniprotkb:Q13181|uniprotkb:Q99K66|uniprotkb:Q13864|uniprotkb:Q96AL0|uniprotkb:Q96B10	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:abce1_human(display_long)|uniprotkb:ABCE1(gene name)|psi-mi:ABCE1(display_short)|uniprotkb:RLI(gene name synonym)|uniprotkb:RNASEL1(gene name synonym)|uniprotkb:RNASELI(gene name synonym)|uniprotkb:RNS4I(gene name synonym)|uniprotkb:RNase L inhibitor(gene name synonym)|uniprotkb:Ribonuclease 4 inhibitor(gene name synonym)|uniprotkb:2'-5'-oligoadenylate-binding protein(gene name synonym)|uniprotkb:HuHP68(gene name synonym)|uniprotkb:OK/SW-cl.40(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000164163(gene)|ensembl:ENST00000296577(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0005506"(iron ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006415"(translational termination)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060698"(endoribonuclease inhibitor activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007209(Possible metal-binding region in RNase L inhibitor, RLI)|interpro:IPR013283(ABC transporter, ABCE)|interpro:IPR017871|interpro:IPR017896|interpro:IPR017900|interpro:IPR027417|interpro:IPR034348|mint:P61221|rcsb pdb:6ZME|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:NP_001035809.1|refseq:NP_002931.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+6ykpRtI4p94M3TuoTzFBvdCsC09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q99798	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2932893|ensembl:ENSP00000216254|uniprotkb:O75809|uniprotkb:Q5JZ41|uniprotkb:Q6FHX0|uniprotkb:Q8TAQ6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acon_human(display_long)|uniprotkb:ACO2(gene name)|psi-mi:ACO2(display_short)|uniprotkb:Citrate hydro-lyase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000100412(gene)|ensembl:ENST00000216254(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q99798|reactome:R-HSA-1268020|reactome:R-HSA-71403|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|refseq:NP_001089.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:QpDlGJHSwqfCktMlwYXKTonXftA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P22830	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1390356|uniprotkb:Q8IXN1|uniprotkb:Q8NAN0|uniprotkb:A8KA72|ensembl:ENSP00000262093	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hemh_human(display_long)|uniprotkb:Protoheme ferro-lyase(gene name synonym)|uniprotkb:Heme synthase(gene name synonym)|uniprotkb:FECH(gene name)|psi-mi:FECH(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000131.2|refseq:NP_001012533.1|dip:DIP-39632N|ensembl:ENSG00000066926(gene)|ensembl:ENST00000262093(transcript)|go:"GO:0004325"(ferrochelatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010288"(response to lead ion)|go:"GO:0017085"(response to insecticide)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0046501"(protoporphyrinogen IX metabolic process)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051597"(response to methylmercury)|go:"GO:0070541"(response to platinum ion)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001015(Ferrochelatase)|interpro:IPR019772|interpro:IPR033644|interpro:IPR033659|rcsb pdb:1HRK|rcsb pdb:2HRC|rcsb pdb:2HRE|rcsb pdb:2PNJ|rcsb pdb:2PO5|rcsb pdb:2PO7|rcsb pdb:2QD1|rcsb pdb:2QD2|rcsb pdb:2QD3|rcsb pdb:2QD4|rcsb pdb:2QD5|rcsb pdb:3AQI|rcsb pdb:3HCN|rcsb pdb:3HCO|rcsb pdb:3HCP|rcsb pdb:3HCR|rcsb pdb:3W1W|rcsb pdb:4F4D|rcsb pdb:4KLA|rcsb pdb:4KLC|rcsb pdb:4KLR|rcsb pdb:4KMM|rcsb pdb:4MK4|reactome:R-HSA-189451	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Rh4ulxUAnCedNUVAABAhY4iOnuo9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H845	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P03891	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246202|uniprotkb:Q34769|uniprotkb:Q9TGI0|uniprotkb:Q9TGI1|uniprotkb:Q9TGI2|uniprotkb:Q9TGI3|uniprotkb:Q9TGI4|ensembl:ENSP00000355046	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nu2m_human(display_long)|uniprotkb:MT-ND2(gene name)|psi-mi:MT-ND2(display_short)|uniprotkb:MTND2(gene name synonym)|uniprotkb:NADH2(gene name synonym)|uniprotkb:ND2(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:YP_003024027.1|ensembl:ENSG00000198763(gene)|ensembl:ENST00000361453(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003917(NADH-ubiquinone oxidoreductase, chain 2)|interpro:IPR010933(NADH dehydrogenase subunit 2, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:GKiEviD5+IEk1TCxgEvUyw6Ys6s9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P03886	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246156|uniprotkb:Q37523|uniprotkb:C0JKH6|ensembl:ENSP00000354687	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nu1m_human(display_long)|uniprotkb:MT-ND1(gene name)|psi-mi:MT-ND1(display_short)|uniprotkb:MTND1(gene name synonym)|uniprotkb:NADH1(gene name synonym)|uniprotkb:ND1(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:YP_003024026.1|ensembl:ENSG00000198888(gene)|ensembl:ENST00000361390(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|interpro:IPR001694(Respiratory-chain NADH dehydrogenase, subunit 1)|interpro:IPR018086|mint:P03886|rcsb pdb:5XTC|rcsb pdb:5XTD|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:AZoXs+VEdQPt/9D2lr+qBuwsZfA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P03905	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246274|uniprotkb:Q6RL39|uniprotkb:Q6RQN9|uniprotkb:Q8HNR8|ensembl:ENSP00000354961	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nu4m_human(display_long)|uniprotkb:MT-ND4(gene name)|psi-mi:MT-ND4(display_short)|uniprotkb:MTND4(gene name synonym)|uniprotkb:NADH4(gene name synonym)|uniprotkb:ND4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:YP_003024035.1|ensembl:ENSG00000198886(gene)|ensembl:ENST00000361381(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0021549"(cerebellum development)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:O+b63kRTlmPDBdo6Oe90fRomfeY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P03915	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246343|uniprotkb:Q34773|uniprotkb:Q8WCY3|ensembl:ENSP00000354813	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nu5m_human(display_long)|uniprotkb:MT-ND5(gene name)|psi-mi:MT-ND5(display_short)|uniprotkb:MTND5(gene name synonym)|uniprotkb:NADH5(gene name synonym)|uniprotkb:ND5(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:YP_003024036.1|ensembl:ENSG00000198786(gene)|ensembl:ENST00000361567(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|interpro:IPR001516("NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal")|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003945(NADH-plastoquinone oxidoreductase, chain 5)|interpro:IPR010934(NADH dehydrogenase subunit 5, C-terminal)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:qQQpmtsDu8cJSW+Re15KtO+tgNs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q8TB37	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-12852610|ensembl:ENSP00000281081|uniprotkb:B4DHZ1|uniprotkb:Q86TZ4|uniprotkb:Q9H9M2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nubpl_human(display_long)|uniprotkb:NUBPL(gene name)|psi-mi:NUBPL(display_short)|uniprotkb:C14orf127(gene name synonym)|uniprotkb:IND1 homolog(gene name synonym)|uniprotkb:Nucleotide-binding protein-like(gene name synonym)|uniprotkb:huInd1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000151413(gene)|ensembl:ENST00000281081(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0070584"(mitochondrion morphogenesis)|interpro:IPR000808(Mrp, conserved site)|interpro:IPR019591|interpro:IPR027417|interpro:IPR033756|interpro:IPR044304|reactome:R-HSA-6799198|refseq:NP_001188502.1|refseq:NP_079428.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:e9UiCfG76k75Df7cMDdOmi/LI7I9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P56181	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-721902|uniprotkb:Q6FGD3|uniprotkb:Q9HCR5|uniprotkb:A8K0M1|uniprotkb:Q8WU60|uniprotkb:J3KNX7|ensembl:ENSP00000342895	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduv3_human(display_long)|uniprotkb:Complex I-9kD(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-4(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 9 kDa subunit(gene name synonym)|uniprotkb:NDUFV3(gene name)|psi-mi:NDUFV3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001001503.1|refseq:NP_066553.3|ensembl:ENSG00000160194(gene)|ensembl:ENST00000340344(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR026193|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:YW1NUj6P01jeBW0dhRhVQaqg7qY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43678	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246398|uniprotkb:Q6IAY8|uniprotkb:D6RJD6|ensembl:ENSP00000252102	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndua2_human(display_long)|uniprotkb:NDUFA2(gene name)|psi-mi:NDUFA2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002479.1|refseq:NP_001171941.1|ensembl:ENSG00000131495(gene)|ensembl:ENST00000252102(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|rcsb pdb:1S3A|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bL66utte1nSuYj0nxg/BoktnXhs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95168	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1245485|uniprotkb:B2RUY3|uniprotkb:B9EJC7|ensembl:ENSP00000184266	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndub4_human(display_long)|uniprotkb:NDUFB4(gene name)|psi-mi:NDUFB4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001161803.1|refseq:NP_004538.2|ensembl:ENSG00000065518(gene)|ensembl:ENST00000184266(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:O7vikmRDGTcfvmDXSThJKj2ADJc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43181	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246139|uniprotkb:Q9BS69|ensembl:ENSP00000296684	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus4_human(display_long)|uniprotkb:NDUFS4(gene name)|psi-mi:NDUFS4(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002486.1|ensembl:ENSG00000164258(gene)|ensembl:ENST00000296684(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007420"(brain development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR006885(ETC complex I subunit conserved region)|interpro:IPR038532|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:T/NnuQagNs7EnceU9XKo4eUdy2o9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9P0J0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-372742|uniprotkb:Q6PKI0|uniprotkb:Q9H2L3|uniprotkb:Q9Y327|uniprotkb:B4DF76|uniprotkb:K7EK58|ensembl:ENSP00000423673	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduad_human(display_long)|uniprotkb:NDUFA13(gene name)|psi-mi:NDUFA13(display_short)|uniprotkb:CGI-39(orf name)|uniprotkb:CDA016(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:GRIM19(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057049.5|go:"GO:0005524"(ATP binding)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010952"(positive regulation of peptidase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0005654"(nucleoplasm)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0005737"(cytoplasm)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9P0J0|rcsb pdb:5XTB|rcsb pdb:5XTC|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|ensembl:ENSG00000186010(gene)|ensembl:ENST00000507754(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|dip:DIP-31180N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:X5AsKHIxU5kpNVjY37UbZXG/Kns9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75380	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-719854|ensembl:ENSP00000274137	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NDUFS6(gene name)|psi-mi:NDUFS6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004544.1|ensembl:ENSG00000145494(gene)|ensembl:ENST00000274137(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:IfpFyQjgJW6a8wA2pNw14stMUL49606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9P032	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2606839|uniprotkb:B2R4J5|ensembl:ENSP00000358272	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduf4_human(display_long)|uniprotkb:NDUFAF4(gene name)|psi-mi:NDUFAF4(display_short)|uniprotkb:C6orf66(gene name synonym)|uniprotkb:HRPAP20(gene name synonym)|uniprotkb:Hormone-regulated proliferation-associated protein of 20 kDa(gene name synonym)|uniprotkb:HSPC125(orf name)|uniprotkb:My013(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_054884.1|ensembl:ENSG00000123545(gene)|ensembl:ENST00000316149(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051607"(defense response to virus)|interpro:IPR009622(Protein of unknown function UPF0240)|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ZtOZIjES2EpHrKzLDdCxl08NKcI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q16718	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75438	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-744216|uniprotkb:A0AV68|ensembl:ENSP00000330787|ensembl:ENSP00000450776|ensembl:ENSP00000451090|ensembl:ENSP00000475170	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndub1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MNLL subunit(gene name synonym)|uniprotkb:Complex I-MNLL(gene name synonym)|uniprotkb:NDUFB1(gene name)|psi-mi:NDUFB1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004536.2|ensembl:ENSG00000183648(gene)|ensembl:ENST00000329559(transcript)|ensembl:ENST00000553514(transcript)|ensembl:ENST00000555441(transcript)|ensembl:ENST00000605997(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016607"(nuclear speck)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012575(MNLL subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FU3iytC6Yu5qzxy8Yim4y6wSVqc9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95169	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-716238|uniprotkb:Q5W144|uniprotkb:Q9UG53|uniprotkb:Q9UJR4|uniprotkb:Q9UQF3|uniprotkb:A8K0L4|intact:EBI-11021395|uniprotkb:Q5W143|uniprotkb:Q5W145|intact:EBI-28971189|ensembl:ENSP00000299166	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndub8_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NDUFB8(gene name)|psi-mi:NDUFB8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000299166|ensembl:ENST00000370320|ensembl:ENSP00000359344|ensembl:ENST00000370322|ensembl:ENSP00000359346|refseq:NP_004995.1|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|rcsb pdb:5XTC|rcsb pdb:5XTD|ensembl:ENSG00000166136(gene)|ensembl:ENST00000299166(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|refseq:NP_001271296.1|refseq:NP_001271297.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:iHF93OOQynl/ZBrUOOp9sAbDZkw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95139	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1053340|uniprotkb:Q6IB84|ensembl:ENSP00000369176|uniprotkb:A8K0Y7|uniprotkb:Q5VYT2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndub6_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B17 subunit(gene name synonym)|uniprotkb:Complex I-B17(gene name synonym)|uniprotkb:NDUFB6(gene name)|psi-mi:NDUFB6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000165264(gene)|ensembl:ENST00000379847(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR019174|mint:O95139|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_877416.1|refseq:NP_002484.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:topkNBeCU1z26byuWjSujC8PshA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43676	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-718365|uniprotkb:Q6IB80|ensembl:ENSP00000237889|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000410600|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndub3_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B12 subunit(gene name synonym)|uniprotkb:Complex I-B12(gene name synonym)|uniprotkb:NDUFB3(gene name)|psi-mi:NDUFB3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002482.1|refseq:XP_011509532.1|refseq:XP_016859675.1|refseq:NP_001244031.1|ensembl:ENSP00000237889|ensembl:ENSP00000410600|ensembl:ENSP00000401834|ensembl:ENSP00000407336|ensembl:ENSP00000507925|ensembl:ENSP00000508132|ensembl:ENSP00000508208|ensembl:ENSG00000119013(gene)|ensembl:ENST00000237889(transcript)|ensembl:ENST00000433898(transcript)|ensembl:ENST00000450023(transcript)|ensembl:ENST00000454214(transcript)|ensembl:ENST00000682325(transcript)|ensembl:ENST00000684175(transcript)|ensembl:ENST00000684420(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012576(NADH-ubiquinone oxidoreductase B12 subunit)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:APgw3aIZyyqiPCXMFJ9dUYPQhVE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43920	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246091|ensembl:ENSP00000362058|ensembl:ENSP00000362060	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus5_human(display_long)|uniprotkb:NDUFS5(gene name)|psi-mi:NDUFS5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 15 kDa subunit(gene name synonym)|uniprotkb:Complex I-15 kDa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001171908.1|refseq:NP_004543.1|ensembl:ENSG00000168653(gene)|ensembl:ENST00000372967(transcript)|ensembl:ENST00000372969(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019342|mint:O43920|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:q74OuEXKdyCuxrUujwHeZjkW2gY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NX14	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246182|uniprotkb:Q5JRR3|uniprotkb:Q5JRR4|uniprotkb:Q6IAB6|uniprotkb:Q8WZ96|uniprotkb:Q9BXX9|ensembl:ENSP00000367042	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndubb_human(display_long)|uniprotkb:NDUFB11(gene name)|psi-mi:NDUFB11(display_short)|uniprotkb:UNQ111/PRO1064(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase ESSS subunit(gene name synonym)|uniprotkb:Complex I-ESSS(gene name synonym)|uniprotkb:Neuronal protein 17.3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001129470.1|refseq:NP_061929.2|ensembl:ENSG00000147123(gene)|ensembl:ENST00000377811(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019329|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:CAloB+PJ0fcnLukpvgNGgTFJ0zs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95298	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246172|uniprotkb:Q9UBJ9|uniprotkb:Q6FIH8|uniprotkb:Q549M5|uniprotkb:E9PNU8|uniprotkb:E9PRB2|ensembl:ENSP00000281031	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduc2_human(display_long)|uniprotkb:NDUFC2(gene name)|psi-mi:NDUFC2(display_short)|uniprotkb:HLC1(orf name)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5b(gene name synonym)|uniprotkb:Complex I-B14.5b(gene name synonym)|uniprotkb:Human lung cancer oncogene 1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004540.1|refseq:NP_001190983.1|refseq:NP_001190984.1|ensembl:ENSG00000151366(gene)|ensembl:ENST00000281031(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005886"(plasma membrane)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR009423(NADH-ubiquinone oxidoreductase subunit b14.5b)|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6798695|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:IILkKsJHyRjCMZJ6z//WjdRXQUQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O43674	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246293|uniprotkb:Q561V6|ensembl:ENSP00000259037	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndub5_human(display_long)|uniprotkb:NDUFB5(gene name)|psi-mi:NDUFB5(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase SGDH subunit(gene name synonym)|uniprotkb:Complex I-SGDH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186886.1|refseq:NP_001186887.1|refseq:NP_002483.1|ensembl:ENSG00000136521(gene)|ensembl:ENST00000259037(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019173|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:1UrbNq39EsuKHJ2M7tRd8ZmB6uk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P56556	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-714658|uniprotkb:O43675|uniprotkb:Q6IC39|uniprotkb:B2RE54|uniprotkb:Q6FGW0|uniprotkb:Q6IBT8|ensembl:ENSP00000418842|ensembl:ENSP00000475402|ensembl:ENSP00000486781|ensembl:ENSP00000487431|ensembl:ENSP00000487462	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndua6_human(display_long)|uniprotkb:LYRM6(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B14 subunit(gene name synonym)|uniprotkb:Complex I-B14(gene name synonym)|uniprotkb:LYR motif-containing protein 6(gene name synonym)|uniprotkb:NDUFA6(gene name)|psi-mi:NDUFA6(display_short)|uniprotkb:NADHB14(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002481.2|ensembl:ENSG00000184983(gene)|ensembl:ENSG00000272765(gene)|ensembl:ENSG00000273397(gene)|ensembl:ENSG00000277365(gene)|ensembl:ENSG00000281013(gene)|ensembl:ENST00000498737(transcript)|ensembl:ENST00000605916(transcript)|ensembl:ENST00000628740(transcript)|ensembl:ENST00000630201(transcript)|ensembl:ENST00000630971(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR016488("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6")|mint:P56556|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:rI1B6Ym+ps0tKfJIClYRtej8KcU9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95182	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-721471|ensembl:ENSP00000301457|ensembl:ENSP00000470962	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndua7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.5a(gene name synonym)|uniprotkb:Complex I-B14.5a(gene name synonym)|uniprotkb:NDUFA7(gene name)|psi-mi:NDUFA7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004992.2|ensembl:ENSG00000267855(gene)|ensembl:ENST00000301457(transcript)|ensembl:ENST00000593729(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032543"(mitochondrial translation)|interpro:IPR009947("NADH:ubiquinone oxidoreductase subunit B14.5a")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FUdu0Oxjx6fLyDbe6WDbyfwKZW89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5TEU4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10762958|uniprotkb:A8K166|uniprotkb:Q6GPH3|uniprotkb:Q9H6F4|ensembl:ENSP00000367346	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduf5_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5(gene name synonym)|uniprotkb:Putative methyltransferase NDUFAF5(gene name synonym)|uniprotkb:NDUFAF5(gene name)|psi-mi:NDUFAF5(display_short)|uniprotkb:C20orf7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001034464.1|refseq:NP_077025.2|ensembl:ENSG00000101247(gene)|ensembl:ENST00000378106(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030961"(peptidyl-arginine hydroxylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0032259"(methylation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q5TEU4|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:BC4jrAunVf7T4Cbrr/sZVFnkrfA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O96000	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246371|uniprotkb:Q96II6|ensembl:ENSP00000268668	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduba_human(display_long)|uniprotkb:NDUFB10(gene name)|psi-mi:NDUFB10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)|uniprotkb:Complex I-PDSW(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004539.1|ensembl:ENSG00000140990(gene)|ensembl:ENST00000268668(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|interpro:IPR019377|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039993|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|dip:DIP-38298N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:CRQJLj/I1jZSnIU7GeuRDGN4hRA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y375	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-741874|uniprotkb:Q9BVZ5|ensembl:ENSP00000260361|ensembl:ENSP00000453944	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:cia30_human(display_long)|uniprotkb:NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1(gene name synonym)|uniprotkb:NDUFAF1(gene name)|psi-mi:NDUFAF1(display_short)|uniprotkb:CIA30(gene name synonym)|uniprotkb:CGI-65(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057097.2|ensembl:ENSG00000137806(gene)|ensembl:ENST00000260361(transcript)|ensembl:ENST00000560978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0010257"(NADH dehydrogenase complex assembly)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013857("NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30")|interpro:IPR039131|mint:Q9Y375|reactome:R-HSA-6799198|refseq:XP_011519960.1|refseq:XP_006720618.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:cZmtaAs6upui/PVTTBGQBEOcWvk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q86Y39	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246415|uniprotkb:Q6ZS66|uniprotkb:C9JT23|ensembl:ENSP00000311740	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduab_human(display_long)|uniprotkb:NDUFA11(gene name)|psi-mi:NDUFA11(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B14.7(gene name synonym)|uniprotkb:Complex I-B14.7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_783313.1|refseq:NP_001180304.1|ensembl:ENSG00000174886(gene)|ensembl:ENST00000308961(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR039205|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:w6WASokPDfLWJ57ntErW7LgdpBA9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UI09	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246332|uniprotkb:Q9BRV6|uniprotkb:Q53XX0|uniprotkb:F8VQS7|ensembl:ENSP00000330737	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduac_human(display_long)|uniprotkb:NDUFA12(gene name)|psi-mi:NDUFA12(display_short)|uniprotkb:DAP13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:13 kDa differentiation-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_061326.1|refseq:NP_001245267.1|ensembl:ENSG00000184752(gene)|ensembl:ENST00000327772(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:bQJVtT1ycebwYktMsNrejTZmG4k9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O95299	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246361|uniprotkb:Q8WXC9|ensembl:ENSP00000252711|ensembl:ENSP00000503956|ensembl:ENSP00000504765	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduaa_human(display_long)|uniprotkb:NDUFA10(gene name)|psi-mi:NDUFA10(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Complex I-42kD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004535.1|ensembl:ENSG00000130414(gene)|ensembl:ENST00000252711(transcript)|ensembl:ENST00000676929(transcript)|ensembl:ENST00000678158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|mint:O95299|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:8jwJPJ0rD9H7A4AzxPd186tpXYs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BU61	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2114801|ensembl:ENSP00000323076	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduf3_human(display_long)|uniprotkb:NDUFAF3(gene name)|psi-mi:NDUFAF3(display_short)|uniprotkb:C3orf60(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_951032.1|ensembl:ENSG00000178057(gene)|ensembl:ENST00000326925(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034095|interpro:IPR036748|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:FRuV8K4v6ogOA5pR2YVCnhRW5oQ9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75306	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1224806|uniprotkb:Q5VTW0|uniprotkb:Q969P3|uniprotkb:Q9UEV3|uniprotkb:J3KPM7|uniprotkb:D3DVG7|intact:EBI-11120296|intact:EBI-28971126|ensembl:ENSP00000356972|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENSP00000504199|ensembl:ENSP00000504846	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus2_human(display_long)|uniprotkb:NDUFS2(gene name)|psi-mi:NDUFS2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSP00000356972|ensembl:ENST00000392179|ensembl:ENSP00000376018|ensembl:ENSP00000503117|ensembl:ENSP00000503989|ensembl:ENST00000677457|ensembl:ENSP00000503294|ensembl:ENST00000677550|ensembl:ENSP00000503353|ensembl:ENSP00000504199|ensembl:ENSP00000504846|ensembl:ENST00000678605|ensembl:ENSP00000503969|ensembl:ENST00000679176|ensembl:ENSP00000504170|refseq:NP_001159631.1|refseq:NP_004541.1|refseq:XP_005245265.1|refseq:XP_016856846.1|ensembl:ENST00000676600(transcript)|ensembl:ENST00000676972(transcript)|ensembl:ENST00000678507(transcript)|ensembl:ENST00000678511(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|ensembl:ENST00000367993(transcript)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:O75306|rcsb pdb:5XTB|rcsb pdb:5XTC|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|ensembl:ENSG00000158864(gene)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ZyGea/CEJ7g/u+3D7SXTtLUAnRY9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75489	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1224896|uniprotkb:Q9UNQ8|uniprotkb:B2R9J1|uniprotkb:B4DFM8|ensembl:ENSP00000263774|ensembl:ENSP00000496383	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus3_human(display_long)|uniprotkb:NDUFS3(gene name)|psi-mi:NDUFS3(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004542.1|ensembl:ENSG00000213619(gene)|ensembl:ENSG00000285387(gene)|ensembl:ENST00000263774(transcript)|ensembl:ENST00000645714(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:O75489|go:"GO:0005739"(mitochondrion)|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408	go:"GO:0043229"(intracellular organelle)	-	crc64:C058D62779BEF17B	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DLJY8qzyEVTyAGgqIjBP24ymiSs9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P49821	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-748312|uniprotkb:Q6IBR3|uniprotkb:O60924|uniprotkb:O60940|uniprotkb:Q16104|uniprotkb:Q96BF8|uniprotkb:Q96HS7|ensembl:ENSP00000322450|ensembl:ENSP00000497587	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduv1_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH dehydrogenase flavoprotein 1(gene name synonym)|uniprotkb:NDUFV1(gene name)|psi-mi:NDUFV1(display_short)|uniprotkb:UQOR1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001159574.1|refseq:NP_009034.2|ensembl:ENSG00000167792(gene)|ensembl:ENST00000322776(transcript)|ensembl:ENST00000647561(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:P49821|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:0pEd6isDBEamZQJ5QNo5yJ7rKu89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P19404	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P28331	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O75251	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00217	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y276	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-719257|uniprotkb:B3KTW9|uniprotkb:Q7Z2V7|ensembl:ENSP00000352219|ensembl:ENSP00000375957|ensembl:ENSP00000375958|ensembl:ENSP00000375959|ensembl:ENSP00000404999|ensembl:ENSP00000406494|ensembl:ENSP00000413908	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:bcs1_human(display_long)|uniprotkb:BCS1-like protein(gene name synonym)|uniprotkb:BCS1L(gene name)|psi-mi:BCS1L(display_short)|uniprotkb:BCS1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001073335.1|refseq:NP_004319.1|ensembl:ENSG00000074582(gene)|ensembl:ENST00000359273(transcript)|ensembl:ENST00000392109(transcript)|ensembl:ENST00000392110(transcript)|ensembl:ENST00000392111(transcript)|ensembl:ENST00000412366(transcript)|ensembl:ENST00000431802(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR014851(BCS1 N terminal)|interpro:IPR027417|reactome:R-HSA-1268020|ensembl:ENST00000439945(transcript)|refseq:NP_001244271.1|refseq:NP_001244272.1|refseq:NP_001244273.1|refseq:NP_001305765.1|refseq:NP_001307646.1|refseq:XP_006712741.1|refseq:XP_016860120.1|refseq:XP_016860121.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:NMfoX75THfvFwzpgBcpKXGmRGcM9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P47985	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5U5X0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:A6NFY7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-12011488|ensembl:ENSP00000368165|uniprotkb:B2RPM7	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sdhf1_human(display_long)|uniprotkb:SDHAF1(gene name)|psi-mi:SDHAF1(display_short)|uniprotkb:LYR motif-containing protein 8(gene name synonym)|uniprotkb:LYRM8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000205138(gene)|ensembl:ENST00000378887(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0034553"(mitochondrial respiratory chain complex II assembly)|interpro:IPR008011(Complex 1 LYR protein)|dip:DIP-62123N|refseq:NP_001036096.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:P6MKaJaP6EffNUZtgj4/S9UxuTE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P21912	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1056481|uniprotkb:Q9NQ12|uniprotkb:Q0QEY7|uniprotkb:B2R545|ensembl:ENSP00000364649	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sdhb_human(display_long)|uniprotkb:SDHB(gene name)|psi-mi:SDHB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002991.2|ensembl:ENSG00000117118(gene)|ensembl:ENST00000375499(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-39666N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:7xnswe3IVEFJiXqGhxF0Az3EmvE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P22570	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1751533|uniprotkb:Q13716|uniprotkb:Q4PJI0|uniprotkb:Q9BU12|uniprotkb:B4DHX5|uniprotkb:B4DDI7|uniprotkb:B4DQQ4|uniprotkb:B4DX24|uniprotkb:B7Z7G2|uniprotkb:E7EQC1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:adro_human(display_long)|uniprotkb:FDXR(gene name)|psi-mi:FDXR(display_short)|uniprotkb:ADXR(gene name synonym)|uniprotkb:"Ferredoxin--NADP(+) reductase"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	interpro:IPR021163|go:"GO:0004324"(ferredoxin-NADP+ reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015039"(NADPH-adrenodoxin reductase activity)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR023753|reactome:R-HSA-196108|reactome:R-HSA-211976|reactome:R-HSA-2395516|reactome:R-HSA-5579026|refseq:NP_001244944.1|refseq:NP_001244941.2|refseq:NP_001244942.2|refseq:NP_001244943.2|refseq:NP_001244945.2|refseq:NP_004101.3|refseq:NP_077728.3|interpro:IPR036188	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:92GnZ67Hkkcric4CcYdICc5kRHE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P10109	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2694652|uniprotkb:B0YJ14|uniprotkb:Q53YD6|ensembl:ENSP00000260270	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:adx_human(display_long)|uniprotkb:ADX(gene name synonym)|uniprotkb:Adrenal ferredoxin(gene name synonym)|uniprotkb:Ferredoxin-1(gene name synonym)|uniprotkb:Hepatoredoxin(gene name synonym)|uniprotkb:FDX1(gene name)|psi-mi:FDX1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_004100.1|ensembl:ENSG00000137714(gene)|ensembl:ENST00000260270(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0042446"(hormone biosynthetic process)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:1904322"(cellular response to forskolin)|interpro:IPR001041(Ferredoxin)|interpro:IPR001055(Adrenodoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR018298|interpro:IPR036010|rcsb pdb:3N9Y|rcsb pdb:3N9Z|rcsb pdb:3NA0|rcsb pdb:3NA1|rcsb pdb:3P1M|rcsb pdb:7M8I|reactome:R-HSA-1362409|reactome:R-HSA-196108|reactome:R-HSA-211976|reactome:R-HSA-2395516|reactome:R-HSA-5579026	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:C6uFdlyqNUgWMeNDQlPYS7MZ4Ho9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9HD34	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3920810|ensembl:ENSP00000418787|uniprotkb:A8K543|uniprotkb:Q5XKP1	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lyrm4_human(display_long)|uniprotkb:LYRM4(gene name)|psi-mi:LYRM4(display_short)|uniprotkb:C6orf149(gene name synonym)|uniprotkb:ISD11(gene name synonym)|uniprotkb:CGI-203(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001158313.1|ensembl:ENSG00000214113(gene)|ensembl:ENST00000330636(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016604"(nuclear body)|go:"GO:1990221"(L-cysteine desulfurase complex)|interpro:IPR008011(Complex 1 LYR protein)|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6ODD|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|refseq:NP_065141.3	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:42Smt00XZS1ZIumThh+hX/ARM7M9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9Y697	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1751791|uniprotkb:E1P5R8|uniprotkb:Q6P0L8|uniprotkb:Q9NTZ5|uniprotkb:Q9Y481|uniprotkb:B3KMA5|uniprotkb:B4DXK9|uniprotkb:F5GYK5|ensembl:ENSP00000363205	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nfs1_human(display_long)|uniprotkb:NFS1(gene name)|psi-mi:NFS1(display_short)|uniprotkb:NIFS(gene name synonym)|uniprotkb:HUSSY-08(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001185918.1|refseq:NP_066923.3|ensembl:ENSG00000244005(gene)|ensembl:ENST00000374092(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031071"(cysteine desulfurase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|interpro:IPR000192(Aminotransferase, class V/Cysteine desulphurase)|interpro:IPR010240(Cysteine desulphurase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR016454(Cysteine desulphurase, NifS)|interpro:IPR020578|rcsb pdb:5KZ5|rcsb pdb:5USR|rcsb pdb:5WGB|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|reactome:R-HSA-947581	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:tSeWDc9Ch78CnCC2Co+vzC2CWvg9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9UMS0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-725252|uniprotkb:Q53QE5|uniprotkb:Q6VNZ8|uniprotkb:Q7Z5B1|uniprotkb:Q7Z5B2|uniprotkb:Q9Y322|uniprotkb:B4DUL9|ensembl:ENSP00000387219	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nfu1_human(display_long)|uniprotkb:HIRA-interacting protein 5(gene name synonym)|uniprotkb:NFU1(gene name)|psi-mi:NFU1(display_short)|uniprotkb:CGI-33(orf name)|uniprotkb:HIRIP5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001002755.1|refseq:NP_056515.2|refseq:NP_001002756.1|ensembl:ENSG00000169599(gene)|ensembl:ENST00000410022(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001075(NIF system FeS cluster assembly, NifU, C-terminal)|interpro:IPR014824(NIF system FeS cluster assembly, NifU-like scaffold, N-terminal)|interpro:IPR034904|interpro:IPR036498|rcsb pdb:2LTM|rcsb pdb:2M5O|refseq:XP_016859297.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ilyUYSw8tpfn8DDWGsj96O6f7jk9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q86SX6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1049910|uniprotkb:Q3YML0|uniprotkb:Q86WY3|uniprotkb:Q8IZ54|uniprotkb:Q0X088|ensembl:ENSP00000328570	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:glrx5_human(display_long)|uniprotkb:GLRX5(gene name)|psi-mi:GLRX5(display_short)|uniprotkb:C14orf87(gene name synonym)|uniprotkb:Monothiol glutaredoxin-5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057501.2|ensembl:ENSG00000182512(gene)|ensembl:ENST00000331334(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0097573"(glutathione oxidoreductase activity)|go:"GO:0106034"(protein maturation by [2Fe-2S] cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR033658|interpro:IPR036249|rcsb pdb:2MMZ|rcsb pdb:2WUL|reactome:R-HSA-1362409|dip:DIP-50654N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+h1VgIFt6kuH/Mc+KUxkB+w9RJI9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5T440	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10714899|ensembl:ENSP00000355672	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:caf17_human(display_long)|uniprotkb:Iron-sulfur cluster assembly factor homolog(gene name synonym)|uniprotkb:IBA57(gene name)|psi-mi:IBA57(display_short)|uniprotkb:C1orf69(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001010867.1|ensembl:ENSG00000181873(gene)|ensembl:ENST00000366711(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016740"(transferase activity)|interpro:IPR017703(Folate-binding, YgfZ)|interpro:IPR027266|rcsb pdb:6GEU|rcsb pdb:6QE3|rcsb pdb:6QE4	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:20ToUTe4EoBuv31juWsDvsuyQY89606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9BUE6	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2866528|uniprotkb:B4DJI5|uniprotkb:B3KP34|uniprotkb:Q8ND75|uniprotkb:Q9BZR2|ensembl:ENSP00000365159	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:isca1_human(display_long)|uniprotkb:ISCA1(gene name)|psi-mi:ISCA1(display_short)|uniprotkb:HBLD2(gene name synonym)|uniprotkb:HESB-like domain-containing protein 2(gene name synonym)|uniprotkb:Iron-sulfur assembly protein IscA(gene name synonym)|uniprotkb:GK004(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_112202.2|ensembl:ENSG00000135070(gene)|ensembl:ENST00000375991(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR000361(HesB/YadR/YfhF-like)|interpro:IPR016092(HesB/YadR/YfhF)|interpro:IPR017870|interpro:IPR035903|reactome:R-HSA-1362409	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:ydND+wkG6OPkv24x5GWefAIa6309606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H1K1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P38646	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13943458|imex:IM-25655-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:1C, table S1|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2021/11/30	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:u7M5yeSd1XZsb6JTof+99Dbcxbk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5U5X0	uniprotkb:P47985	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944918|imex:IM-25655-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	go:"GO:0005739"(mitochondrion)	-	-	figure legend:1E|comment:HSC20 is knocked down in the experiment used to detect this interaction.|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rigid:JAsIvvXAQKMjh+4zevV5EdvmVFQ	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q9H1K1	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944933|imex:IM-25655-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0005739"(mitochondrion)	-	-	figure legend:1E, 2A|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:P38646	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944933|imex:IM-25655-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0005739"(mitochondrion)	-	-	figure legend:1E, 2A|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q8IWL3	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944933|imex:IM-25655-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005739"(mitochondrion)	-	-	figure legend:1E, 2A|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q5U5X0	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944933|imex:IM-25655-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	go:"GO:0005739"(mitochondrion)	-	-	figure legend:1E, 2A|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:Q9H1K1	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944970|imex:IM-25655-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0005739"(mitochondrion)	-	-	figure legend:1F, S1B-F|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	tandem tag:c-c|mutation decreasing interaction strength:25-25|mutation decreasing interaction strength:10-12|mutation decreasing interaction strength:21-23	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:P38646	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944970|imex:IM-25655-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0005739"(mitochondrion)	-	-	figure legend:1F, S1B-F|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	tandem tag:c-c|mutation decreasing interaction strength:25-25|mutation decreasing interaction strength:10-12|mutation decreasing interaction strength:21-23	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:Q8IWL3	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944970|imex:IM-25655-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005739"(mitochondrion)	-	-	figure legend:1F, S1B-F|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	tandem tag:c-c|mutation decreasing interaction strength:25-25|mutation decreasing interaction strength:10-12|mutation decreasing interaction strength:21-23	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:P47985	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944970|imex:IM-25655-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	go:"GO:0005739"(mitochondrion)	-	-	figure legend:1F, S1B-F|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	tandem tag:c-c|mutation decreasing interaction strength:25-25|mutation decreasing interaction strength:10-12|mutation decreasing interaction strength:21-23	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q9H1K1	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944998|imex:IM-25655-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2A|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:P38646	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944998|imex:IM-25655-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2A|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q8IWL3	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944998|imex:IM-25655-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2A|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q5U5X0	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13944998|imex:IM-25655-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2A|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q5U5X0	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945113|imex:IM-25655-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2A|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rigid:JAsIvvXAQKMjh+4zevV5EdvmVFQ	false	flag tag:c-c	ha tag:c-c|mutation:10-12	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P19404	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945492|imex:IM-25655-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:S2|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606	rigid:tz+vae8dzEjF3OjQ15XHh23vpMI	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:O00217	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945492|imex:IM-25655-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:S2|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606	rigid:tz+vae8dzEjF3OjQ15XHh23vpMI	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P28331	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945492|imex:IM-25655-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:S2|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	rigid:tz+vae8dzEjF3OjQ15XHh23vpMI	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P19404	uniprotkb:Q8IWL3	intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short)	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13953159|imex:IM-25655-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:"S2 (right handside)"|comment:Mitochondrial matrix extracts were used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/22	rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rigid:zcbbmv5qROZGbzDR7pF52hOHXgw	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:Q9NNW7	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10763091|uniprotkb:O95840|uniprotkb:Q96IJ2|uniprotkb:Q9H2Z5|uniprotkb:Q9NZV3|uniprotkb:Q9NZV4|uniprotkb:Q9P2Y0|uniprotkb:Q9P2Y1|uniprotkb:Q9UQU8|ensembl:ENSP00000383365	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:trxr2_human(display_long)|uniprotkb:Selenoprotein Z(gene name synonym)|uniprotkb:TR-beta(gene name synonym)|uniprotkb:Thioredoxin reductase TR3(gene name synonym)|uniprotkb:TXNRD2(gene name)|psi-mi:TXNRD2(display_short)|uniprotkb:KIAA1652(gene name synonym)|uniprotkb:TRXR2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_006431.2|ensembl:ENSG00000184470(gene)|ensembl:ENST00000400521(transcript)|go:"GO:0000305"(response to oxygen radical)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006338(Thioredoxin and glutathione reductase selenoprotein)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:1W1E|reactome:R-HSA-3299685	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Ox9OHgRY9QSgL+ib9RKDVkIu7b49606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NYY8	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1055752|uniprotkb:Q9NVX6|uniprotkb:Q9Y2H7|ensembl:ENSP00000236980|ensembl:ENSP00000384929|ensembl:ENSP00000385990|intact:EBI-21354662	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:fakd2_human(display_long)|uniprotkb:FASTKD2(gene name)|psi-mi:FASTKD2(display_short)|uniprotkb:KIAA0971(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001129665.1|refseq:NP_001129666.1|refseq:NP_055744.2|ensembl:ENST00000402774(transcript)|ensembl:ENST00000403094(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006396"(RNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044528"(regulation of mitochondrial mRNA stability)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR010622(FAST kinase leucine-rich)|interpro:IPR013579(FAST kinase-like protein, subdomain 2)|interpro:IPR013584(RAP domain)|ensembl:ENST00000236980(transcript)|ensembl:ENSG00000118246(gene)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:b7H58ZWEhq5IFl+wO3fsez1v+1U9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P13995	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1058895|ensembl:ENSP00000377617|uniprotkb:Q7Z650|uniprotkb:Q53G90|uniprotkb:Q53GV5|uniprotkb:Q53S36	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mtdc_human(display_long)|uniprotkb:MTHFD2(gene name)|psi-mi:MTHFD2(display_short)|uniprotkb:NMDMC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000065911(gene)|ensembl:ENST00000394053(transcript)|go:"GO:0000287"(magnesium ion binding)|rcsb pdb:1ZN4|rcsb pdb:5TC4|rcsb pdb:6JIB|rcsb pdb:6JID|go:"GO:0004477"(methenyltetrahydrofolate cyclohydrolase activity)|go:"GO:0004487"("methylenetetrahydrofolate dehydrogenase (NAD+) activity")|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020630|interpro:IPR020631|interpro:IPR020867|interpro:IPR036291|rcsb pdb:6KG2|refseq:XP_006711987.1|refseq:NP_006627.2|reactome:R-HSA-196757	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:dzNq2WEcKJ3DptZUIAnyKCITCsk9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q6YN16	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1056665|uniprotkb:A8K1L4|uniprotkb:A8K8X1|uniprotkb:A8MSV3|uniprotkb:Q658M8|uniprotkb:Q9BT58|ensembl:ENSP00000381785	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:hsdl2_human(display_long)|uniprotkb:HSDL2(gene name)|psi-mi:HSDL2(display_short)|uniprotkb:C9orf99(gene name synonym)|uniprotkb:SDR13C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 13C member 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001182751.1|refseq:NP_115679.2|ensembl:ENSG00000119471(gene)|ensembl:ENST00000398805(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR003033(Sterol-binding)|interpro:IPR020904|interpro:IPR036291|interpro:IPR036527|rcsb pdb:3KVO	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:9p5t2957ZP6MwNTNgdfX0rUepnI9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NZL9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-10317491|uniprotkb:B2R5Y6|uniprotkb:Q6NYC7|uniprotkb:Q27J92|uniprotkb:Q9BS89|uniprotkb:Q9H3E1|uniprotkb:Q3LIE8|uniprotkb:Q9UJ54|uniprotkb:Q1WAI7|uniprotkb:Q567T7|ensembl:ENSP00000325425	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:mat2b_human(display_long)|uniprotkb:MAT2B(gene name)|psi-mi:MAT2B(display_short)|uniprotkb:Methionine adenosyltransferase II beta(gene name synonym)|uniprotkb:Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase(gene name synonym)|uniprotkb:TGR(gene name synonym)|uniprotkb:MSTP045(orf name)|uniprotkb:Nbla02999(orf name)|uniprotkb:UNQ2435/PRO4995(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_037415.1|refseq:NP_877725.1|ensembl:ENSG00000038274(gene)|ensembl:ENST00000321757(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0048270"(methionine adenosyltransferase regulator activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005913(dTDP-4-dehydrorhamnose reductase)|interpro:IPR029903|interpro:IPR036291|rcsb pdb:2YDX|rcsb pdb:2YDY|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|reactome:R-HSA-156581|reactome:R-HSA-5689880	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RxXcRktcrFe+9xm7qgSyZoci4rU9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5JTZ9	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-308736|uniprotkb:Q8N198|uniprotkb:Q96D02|uniprotkb:Q9ULF0|uniprotkb:A2RRN5|ensembl:ENSP00000244571	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:syam_human(display_long)|uniprotkb:KIAA1270(gene name synonym)|uniprotkb:AARS2(gene name)|psi-mi:AARS2(display_short)|uniprotkb:AARSL(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_065796.1|ensembl:ENSG00000124608(gene)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:Q5JTZ9|rcsb pdb:6NLQ|rcsb pdb:6NLY|rcsb pdb:6NOW|reactome:R-HSA-379726|ensembl:ENST00000244571(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006400"(tRNA modification)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0070143"(mitochondrial alanyl-tRNA aminoacylation)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:RzNZMsaNjWpD4eB5AdgpjhC3vP09606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P13804	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1052886|uniprotkb:B4DT43|uniprotkb:Q53XN3|ensembl:ENSP00000452762	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:etfa_human(display_long)|uniprotkb:ETFA(gene name)|psi-mi:ETFA(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_000117.1|refseq:NP_001121188.1|dip:DIP-6161N|ensembl:ENSG00000140374(gene)|ensembl:ENST00000557943(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947|mint:P13804|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:J2PUTTVN+nd8eHe6TXga+37CiPw9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P38117	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1056543|uniprotkb:Q6IBH7|uniprotkb:Q71RF6|uniprotkb:Q9Y3S7|uniprotkb:B3KNY2|uniprotkb:A8K766|ensembl:ENSP00000311930	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:etfb_human(display_long)|uniprotkb:ETFB(gene name)|psi-mi:ETFB(display_short)|uniprotkb:FP585(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001014763.1|refseq:NP_001976.1|dip:DIP-6162N|ensembl:ENSG00000105379(gene)|ensembl:ENST00000309244(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|interpro:IPR000049(Electron transfer flavoprotein, beta-subunit, core)|interpro:IPR012255(Electron transfer flavoprotein, beta subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR033948|rcsb pdb:1EFV|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:2A1U|reactome:R-HSA-611105|reactome:R-HSA-8876725	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:Fip+C+sJJhYoSZXwU/FZvabPAEY9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9NSE4	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1054770|uniprotkb:B2RPG8|uniprotkb:Q1M2P9|uniprotkb:Q6PI85|uniprotkb:Q7L439|uniprotkb:Q86WU9|uniprotkb:Q96D91|uniprotkb:Q9H9Q8|uniprotkb:Q9NW42|ensembl:ENSP00000355889	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:syim_human(display_long)|uniprotkb:IARS2(gene name)|psi-mi:IARS2(display_short)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_060530.3|ensembl:ENSG00000067704(gene)|ensembl:ENST00000366922(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010663(DNA glycosylase/AP lyase and isoleucyl tRNA synthetase, zinc finger domain)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023585|interpro:IPR033708|mint:Q9NSE4|reactome:R-HSA-379726	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:+3/hUjD0USVo2/G+Z9aOKpQKwhE9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q12931	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P56556	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-714658|uniprotkb:O43675|uniprotkb:Q6IC39|uniprotkb:B2RE54|uniprotkb:Q6FGW0|uniprotkb:Q6IBT8|ensembl:ENSP00000418842|ensembl:ENSP00000475402|ensembl:ENSP00000486781|ensembl:ENSP00000487431|ensembl:ENSP00000487462	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndua6_human(display_long)|uniprotkb:LYRM6(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B14 subunit(gene name synonym)|uniprotkb:Complex I-B14(gene name synonym)|uniprotkb:LYR motif-containing protein 6(gene name synonym)|uniprotkb:NDUFA6(gene name)|psi-mi:NDUFA6(display_short)|uniprotkb:NADHB14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002481.2|ensembl:ENSG00000184983(gene)|ensembl:ENSG00000272765(gene)|ensembl:ENSG00000273397(gene)|ensembl:ENSG00000277365(gene)|ensembl:ENSG00000281013(gene)|ensembl:ENST00000498737(transcript)|ensembl:ENST00000605916(transcript)|ensembl:ENST00000628740(transcript)|ensembl:ENST00000630201(transcript)|ensembl:ENST00000630971(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR016488("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6")|mint:P56556|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:rI1B6Ym+ps0tKfJIClYRtej8KcU9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H845	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2510719|ensembl:ENSP00000312618|ensembl:ENSP00000506340|uniprotkb:Q8WXX3|uniprotkb:D3DNB8	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acad9_human(display_long)|uniprotkb:ACAD9(gene name)|psi-mi:ACAD9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000177646(gene)|ensembl:ENST00000308982(transcript)|ensembl:ENST00000681583(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|reactome:R-HSA-6799198|go:"GO:0050660"(flavin adenine dinucleotide binding)|refseq:NP_054768.2|dip:DIP-53699N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:1ev99zlKVgMW3KWlcSdzmTtMTvA9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P53597	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1237145|uniprotkb:Q9BWB0|uniprotkb:Q9UNP6|ensembl:ENSP00000377446	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:suca_human(display_long)|uniprotkb:SUCLG1(gene name)|psi-mi:SUCLG1(display_short)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_003840.2|ensembl:ENSG00000163541(gene)|ensembl:ENST00000393868(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR033847|interpro:IPR036291|mint:P53597|rcsb pdb:6G4Q|rcsb pdb:6WCV|reactome:R-HSA-71403	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:fti5qbvs9ndhRyZyoPEuTxMpEgo9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q96I99	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2511878|ensembl:ENSP00000307432|uniprotkb:Q8WUQ1|uniprotkb:Q86VX8|uniprotkb:O95195|uniprotkb:Q6NUH7|uniprotkb:C9JVT2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sucb2_human(display_long)|uniprotkb:SUCLG2(gene name)|psi-mi:SUCLG2(display_short)|uniprotkb:GTP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-G chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000172340(gene)|ensembl:ENST00000307227(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034722|mint:Q96I99|rcsb pdb:6WCV|reactome:R-HSA-71403|refseq:NP_001171070.1|refseq:NP_003839.2|dip:DIP-53563N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:jxrFGuu3hFn2QAYfrPxTKhScM249606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P48735	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-3931130|uniprotkb:Q96GT3|uniprotkb:B2R6L6|ensembl:ENSP00000331897|uniprotkb:B4DFL2	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:idhp_human(display_long)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000182054(gene)|ensembl:ENST00000330062(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P48735|rcsb pdb:4JA8|rcsb pdb:5GIS|rcsb pdb:5I95|rcsb pdb:5I96|rcsb pdb:5SVN|rcsb pdb:5SVO|rcsb pdb:6ADI|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VFZ|reactome:R-HSA-2151201|reactome:R-HSA-71403|refseq:NP_002159.2|refseq:NP_001276839.1|refseq:NP_001277043.1|dip:DIP-61416N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:CeuTM4HmOk3+OKkWlOt9JfNlCIM9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q99798	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-2932893|ensembl:ENSP00000216254|uniprotkb:O75809|uniprotkb:Q5JZ41|uniprotkb:Q6FHX0|uniprotkb:Q8TAQ6	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:acon_human(display_long)|uniprotkb:ACO2(gene name)|psi-mi:ACO2(display_short)|uniprotkb:Citrate hydro-lyase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000100412(gene)|ensembl:ENST00000216254(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q99798|reactome:R-HSA-1268020|reactome:R-HSA-71403|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|refseq:NP_001089.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:QpDlGJHSwqfCktMlwYXKTonXftA9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:O00217	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P19404	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P28331	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P21912	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1056481|uniprotkb:Q9NQ12|uniprotkb:Q0QEY7|uniprotkb:B2R545|ensembl:ENSP00000364649	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:sdhb_human(display_long)|uniprotkb:SDHB(gene name)|psi-mi:SDHB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002991.2|ensembl:ENSG00000117118(gene)|ensembl:ENST00000375499(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-39666N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:7xnswe3IVEFJiXqGhxF0Az3EmvE9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P47985	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q5U5X0	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:Q9H1K1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWL3	uniprotkb:P38646	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945143|imex:IM-25655-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0043229"(intracellular organelle)	-	-	figure legend:2D, table S2|comment:The organellar fraction of HEK293 cells was used in this experiment.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2018/07/05	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:kbIgv0MSW1RmsYKKNb06eb90Uao	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P47985	uniprotkb:Q9H1K1	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945251|imex:IM-25655-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2B|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|comment:This group of proteins were identified as the CIIIb complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:P38646	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945251|imex:IM-25655-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2B|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|comment:This group of proteins were identified as the CIIIb complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q8IWL3	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945251|imex:IM-25655-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2B|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|comment:This group of proteins were identified as the CIIIb complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47985	uniprotkb:Q5U5X0	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945251|imex:IM-25655-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2B|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|comment:This group of proteins were identified as the CIIIb complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rigid:ejvrm+u/e9XAl2kKU+JHO5xOIXw	false	flag tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:P47985	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945272|imex:IM-25655-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2B|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|comment:This group of proteins were identified as the CIIIa complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rigid:JAsIvvXAQKMjh+4zevV5EdvmVFQ	false	ha tag:c-c	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:P47985	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945288|imex:IM-25655-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	go:"GO:0005739"(mitochondrion)	-	-	figure legend:2B|comment:Mitochondrial matrix extracts were used in this experiment.|comment:Endogenous LYRM7 was knocked-down in the experiment used to detect this interaction.|comment:This group of proteins were identified as the CIIIa complex. When the leu_phe_lys10-12ala_ala_ala mutation was present, no CIIIb complex was detected.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	rigid:JAsIvvXAQKMjh+4zevV5EdvmVFQ	false	ha tag:c-c|mutation:10-12	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P19404	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-713665|uniprotkb:Q9BV41|ensembl:ENSP00000327268	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:nduv2_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:NDUFV2(gene name)|psi-mi:NDUFV2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945438|imex:IM-25655-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	ensembl:ENSG00000178127(gene)|ensembl:ENST00000318388(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19404|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|refseq:NP_066552.2	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3D,E|comment:Mitochondrial matrix extracts were used in this experiment.|comment:146 kDa band on the Blue Native-PAGE dimension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:5cG/vsBAIJGKAkWlM0S/rmqJqGM9606	rigid:OC+sOr9uasNFjU3FbWki6QEDfrE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:O00217	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945438|imex:IM-25655-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3D,E|comment:Mitochondrial matrix extracts were used in this experiment.|comment:146 kDa band on the Blue Native-PAGE dimension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606	rigid:OC+sOr9uasNFjU3FbWki6QEDfrE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P28331	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945438|imex:IM-25655-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3D,E|comment:Mitochondrial matrix extracts were used in this experiment.|comment:146 kDa band on the Blue Native-PAGE dimension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	rigid:OC+sOr9uasNFjU3FbWki6QEDfrE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:Q9H1K1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945438|imex:IM-25655-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3D,E|comment:Mitochondrial matrix extracts were used in this experiment.|comment:146 kDa band on the Blue Native-PAGE dimension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:OC+sOr9uasNFjU3FbWki6QEDfrE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P38646	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945438|imex:IM-25655-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3D,E|comment:Mitochondrial matrix extracts were used in this experiment.|comment:146 kDa band on the Blue Native-PAGE dimension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:OC+sOr9uasNFjU3FbWki6QEDfrE	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:O00217	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1246309|uniprotkb:Q0VDA8|uniprotkb:B2RB86|ensembl:ENSP00000315774	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus8_human(display_long)|uniprotkb:NDUFS8(gene name)|psi-mi:NDUFS8(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:TYKY subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945463|imex:IM-25655-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_002487.1|refseq:XP_011543355.1|refseq:XP_005274070.1|refseq:XP_005274071.1|ensembl:ENSG00000110717(gene)|ensembl:ENST00000313468(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:O00217|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3D,E|comment:Mitochondrial matrix extracts were used in this experiment.|comment:242 kDa band on the Blue Native-PAGE dimension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:VzxtzGTNMccCfBDeDy9LKDN5V289606	rigid:s4txw2MxDK7VxZudMoJtH7E3utk	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P28331	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1043922|uniprotkb:B4DPG1|uniprotkb:B4DUC1|uniprotkb:Q53TR8|uniprotkb:Q8N1C4|uniprotkb:Q8TCC9|ensembl:ENSP00000233190|ensembl:ENSP00000399912|ensembl:ENSP00000489640|ensembl:ENSP00000490898|uniprotkb:B4DJA0|uniprotkb:B4DIN9|uniprotkb:E7ENF3	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:ndus1_human(display_long)|uniprotkb:NDUFS1(gene name)|psi-mi:NDUFS1(display_short)|uniprotkb:Complex I-75kD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945463|imex:IM-25655-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_001186913.1|refseq:NP_004997.4|ensembl:ENSG00000023228(gene)|ensembl:ENSG00000283447(gene)|ensembl:ENST00000233190(transcript)|ensembl:ENST00000449699(transcript)|ensembl:ENST00000635748(transcript)|ensembl:ENST00000636505(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:P28331|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|go:"GO:0005758"(mitochondrial intermembrane space)|refseq:NP_001186911.1|refseq:NP_001186912.1|refseq:NP_001186910.1	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3D,E|comment:Mitochondrial matrix extracts were used in this experiment.|comment:242 kDa band on the Blue Native-PAGE dimension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xznBU7fYzFPWvWbs2c/Q+8hV1Kw9606	rigid:s4txw2MxDK7VxZudMoJtH7E3utk	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:Q9H1K1	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-1047335|uniprotkb:Q6P713|uniprotkb:Q99617|uniprotkb:Q9H1K2|ensembl:ENSP00000310623	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:iscu_human(display_long)|uniprotkb:NifU-like N-terminal domain-containing protein(gene name synonym)|uniprotkb:ISCU(gene name)|psi-mi:ISCU(display_short)|uniprotkb:NIFUN(gene name synonym)|uniprotkb:NifU-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945463|imex:IM-25655-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	refseq:NP_055116.1|refseq:NP_998760.1|refseq:NP_001306971.1|dip:DIP-39616N|ensembl:ENSG00000136003(gene)|ensembl:ENST00000311893(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1904439"(negative regulation of iron ion import across plasma membrane)|interpro:IPR002871(NIF system FeS cluster assembly, NifU, N-terminal)|interpro:IPR011339(ISC system FeS cluster assembly, IscU scaffold)|mint:Q9H1K1|rcsb pdb:5KZ5|rcsb pdb:5WKP|rcsb pdb:5WLW|rcsb pdb:6NZU|rcsb pdb:6UXE|rcsb pdb:6W1D|rcsb pdb:6WI2|rcsb pdb:6WIH|reactome:R-HSA-1362409|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3D,E|comment:Mitochondrial matrix extracts were used in this experiment.|comment:242 kDa band on the Blue Native-PAGE dimension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:/4n8Oot3LAX0qwANOsPFL8sDtrE9606	rigid:s4txw2MxDK7VxZudMoJtH7E3utk	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8IWL3	uniprotkb:P38646	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945463|imex:IM-25655-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	go:"GO:0005759"(mitochondrial matrix)	-	-	figure legend:3D,E|comment:Mitochondrial matrix extracts were used in this experiment.|comment:242 kDa band on the Blue Native-PAGE dimension.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/07	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:s4txw2MxDK7VxZudMoJtH7E3utk	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5U5X0	uniprotkb:Q8IWL3	intact:EBI-13943106|ensembl:ENSP00000368688|uniprotkb:A8MPQ9|uniprotkb:Q86Y68	intact:EBI-1805738|uniprotkb:Q9BWS7|ensembl:ENSP00000216027	psi-mi:lyrm7_human(display_long)|uniprotkb:LYRM7(gene name)|psi-mi:LYRM7(display_short)|uniprotkb:C5orf31(gene name synonym)|uniprotkb:MZM1L(gene name synonym)|uniprotkb:LYR motif-containing protein 7(gene name synonym)	psi-mi:hsc20_human(display_long)|uniprotkb:HSCB(gene name)|psi-mi:HSCB(display_short)|uniprotkb:DNAJC20(gene name synonym)|uniprotkb:HSC20(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 20(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13945519|imex:IM-25655-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186687(gene)|ensembl:ENST00000379380(transcript)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0045333"(cellular respiration)|interpro:IPR008011(Complex 1 LYR protein)|refseq:NP_859056.2|dip:DIP-62113N	refseq:NP_741999.3|dip:DIP-46570N|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR004640(Co-chaperone Hsc20)|interpro:IPR009073(Heat shock cognate protein B, C-terminal oligomerisation)|go:"GO:0016226"(iron-sulfur cluster assembly)|interpro:IPR036386|interpro:IPR036869|interpro:IPR040682|rcsb pdb:3BVO|reactome:R-HSA-1268020|reactome:R-HSA-1362409|ensembl:ENSG00000100209(gene)|ensembl:ENST00000216027(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:1G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/03/06	2017/03/22	rogid:82CB6X9AnoWIaqlhMmowBDrn5SE9606	rogid:7LEm+s/QM9R2FExi4iPC8OMp54Y9606	rigid:jUd0+ZiN3V3fHqWI0gzg05dBWZ4	false	ha tag:c-c|35s radiolabel:?-?|mutation disrupting interaction strength:10-12|mutation with no effect:21-23|mutation with no effect:25-25	tandem tag:c-c|35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
chebi:"CHEBI:18248"	uniprotkb:P47985	intact:EBI-1252632	intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397	psi-mi:iron(display_short)|psi-mi:"CHEBI:18248"(display_long)	psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Maio et al. (2017)	pubmed:28380382|imex:IM-25655	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-13953360|imex:IM-25655-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:2E,F|comment:"Interaction decreases if LYRM7 is knocked-down. Mutant version of LYRM7 (LFK-AAA) fails to rescue the knock-down effect, but wild type does."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/03/06	2017/03/22	-	rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606	-	false	radiolabel:?-?	flag tag:c-c	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)