#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O00322	uniprotkb:P35247	intact:EBI-14031976|uniprotkb:Q3KNU5|uniprotkb:Q3KNU6|ensembl:ENSP00000222275|ensembl:ENSP00000483176	intact:EBI-11316157|uniprotkb:Q5T0M3|uniprotkb:Q6FH08|uniprotkb:Q86YK9|uniprotkb:Q8TCD8|uniprotkb:Q9UCJ2|uniprotkb:Q9UCJ3|ensembl:ENSP00000361366	psi-mi:upk1a_human(display_long)|uniprotkb:UPK1A(gene name)|psi-mi:UPK1A(display_short)|uniprotkb:TSPAN21(gene name synonym)|uniprotkb:Uroplakin Ia(gene name synonym)|uniprotkb:Tetraspanin-21(gene name synonym)	psi-mi:sftpd_human(display_long)|uniprotkb:SFTPD(gene name)|psi-mi:SFTPD(display_short)|uniprotkb:COLEC7(gene name synonym)|uniprotkb:PSPD(gene name synonym)|uniprotkb:SFTP4(gene name synonym)|uniprotkb:Collectin-7(gene name synonym)|uniprotkb:Lung surfactant protein D(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Hashimoto et al. (2017)	pubmed:28228557|imex:IM-26025	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-14031974|imex:IM-26025-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268372.1|refseq:NP_008931.1|ensembl:ENSG00000105668(gene)|ensembl:ENST00000222275(transcript)|ensembl:ENST00000617999(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034765	refseq:NP_003010.4|refseq:XP_011538389.1|rcsb pdb:2GGU|rcsb pdb:2GGX|rcsb pdb:2ORJ|rcsb pdb:2ORK|rcsb pdb:2OS9|rcsb pdb:2RIA|rcsb pdb:2RIB|rcsb pdb:2RIC|rcsb pdb:2RID|rcsb pdb:2RIE|rcsb pdb:3DBZ|rcsb pdb:3G81|rcsb pdb:3G83|rcsb pdb:3G84|rcsb pdb:3IKN|rcsb pdb:3IKP|rcsb pdb:3IKQ|rcsb pdb:3IKR|rcsb pdb:4E52|rcsb pdb:4M17|rcsb pdb:4M18|rcsb pdb:5OXR|rcsb pdb:5OXS|reactome:R-HSA-166016|reactome:R-HSA-168179|reactome:R-HSA-198933|reactome:R-HSA-391160|reactome:R-HSA-5683826|reactome:R-HSA-5686938|reactome:R-HSA-5688849|reactome:R-HSA-5688890|ensembl:ENSG00000133661(gene)|ensembl:ENST00000372292(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048286"(lung alveolus development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0052405"|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1905226"(regulation of adhesion of symbiont to host epithelial cell)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR015097(Lung surfactant protein D coiled-coil trimerisation)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033990|rcsb pdb:1B08|rcsb pdb:1M7L|rcsb pdb:1PW9|rcsb pdb:1PWB	-	-	-	figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/04/13	2017/05/10	rogid:/W9BzFoQXsagQQwLySUl280GnQk9606	rogid:YVPGpA6rwjdTjpc67Y8V8EoFiWo9606	rigid:xvtwq++ucv2ce81h6vW2xv4d+No	false	flag tag:c-c	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
chebi:"CHEBI:37684"	uniprotkb:O00322	intact:EBI-14032013|chebi:"CHEBI:14575"|chebi:"CHEBI:33930"	intact:EBI-14031976|uniprotkb:Q3KNU5|uniprotkb:Q3KNU6|ensembl:ENSP00000222275|ensembl:ENSP00000483176	psi-mi:mannose(display_short)|psi-mi:"CHEBI:37684"(display_long)|intact:Man(synonym)|intact:mannose(synonym)|intact:manno-hexose(iupac name)|intact:mannose(iupac name)	psi-mi:upk1a_human(display_long)|uniprotkb:UPK1A(gene name)|psi-mi:UPK1A(display_short)|uniprotkb:TSPAN21(gene name synonym)|uniprotkb:Uroplakin Ia(gene name synonym)|uniprotkb:Tetraspanin-21(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Hashimoto et al. (2017)	pubmed:28228557|imex:IM-26025	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-14032021|imex:IM-26025-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001268372.1|refseq:NP_008931.1|ensembl:ENSG00000105668(gene)|ensembl:ENST00000222275(transcript)|ensembl:ENST00000617999(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034765	-	-	-	figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/04/13	2017/04/13	-	rogid:/W9BzFoQXsagQQwLySUl280GnQk9606	-	false	-	flag tag:c-c	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O00322	uniprotkb:P35247	intact:EBI-14031976|uniprotkb:Q3KNU5|uniprotkb:Q3KNU6|ensembl:ENSP00000222275|ensembl:ENSP00000483176	intact:EBI-11316157|uniprotkb:Q5T0M3|uniprotkb:Q6FH08|uniprotkb:Q86YK9|uniprotkb:Q8TCD8|uniprotkb:Q9UCJ2|uniprotkb:Q9UCJ3|ensembl:ENSP00000361366	psi-mi:upk1a_human(display_long)|uniprotkb:UPK1A(gene name)|psi-mi:UPK1A(display_short)|uniprotkb:TSPAN21(gene name synonym)|uniprotkb:Uroplakin Ia(gene name synonym)|uniprotkb:Tetraspanin-21(gene name synonym)	psi-mi:sftpd_human(display_long)|uniprotkb:SFTPD(gene name)|psi-mi:SFTPD(display_short)|uniprotkb:COLEC7(gene name synonym)|uniprotkb:PSPD(gene name synonym)|uniprotkb:SFTP4(gene name synonym)|uniprotkb:Collectin-7(gene name synonym)|uniprotkb:Lung surfactant protein D(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Hashimoto et al. (2017)	pubmed:28228557|imex:IM-26025	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-14032021|imex:IM-26025-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268372.1|refseq:NP_008931.1|ensembl:ENSG00000105668(gene)|ensembl:ENST00000222275(transcript)|ensembl:ENST00000617999(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034765	refseq:NP_003010.4|refseq:XP_011538389.1|rcsb pdb:2GGU|rcsb pdb:2GGX|rcsb pdb:2ORJ|rcsb pdb:2ORK|rcsb pdb:2OS9|rcsb pdb:2RIA|rcsb pdb:2RIB|rcsb pdb:2RIC|rcsb pdb:2RID|rcsb pdb:2RIE|rcsb pdb:3DBZ|rcsb pdb:3G81|rcsb pdb:3G83|rcsb pdb:3G84|rcsb pdb:3IKN|rcsb pdb:3IKP|rcsb pdb:3IKQ|rcsb pdb:3IKR|rcsb pdb:4E52|rcsb pdb:4M17|rcsb pdb:4M18|rcsb pdb:5OXR|rcsb pdb:5OXS|reactome:R-HSA-166016|reactome:R-HSA-168179|reactome:R-HSA-198933|reactome:R-HSA-391160|reactome:R-HSA-5683826|reactome:R-HSA-5686938|reactome:R-HSA-5688849|reactome:R-HSA-5688890|ensembl:ENSG00000133661(gene)|ensembl:ENST00000372292(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048286"(lung alveolus development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0052405"|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1905226"(regulation of adhesion of symbiont to host epithelial cell)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR015097(Lung surfactant protein D coiled-coil trimerisation)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033990|rcsb pdb:1B08|rcsb pdb:1M7L|rcsb pdb:1PW9|rcsb pdb:1PWB	-	-	-	figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/04/13	2017/04/13	rogid:/W9BzFoQXsagQQwLySUl280GnQk9606	rogid:YVPGpA6rwjdTjpc67Y8V8EoFiWo9606	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O00322	uniprotkb:P08191	intact:EBI-14031976|uniprotkb:Q3KNU5|uniprotkb:Q3KNU6|ensembl:ENSP00000222275|ensembl:ENSP00000483176	intact:EBI-1028015|uniprotkb:Q2M5Z3|ensemblbacteria:AAC77276|ensemblbacteria:BAE78313	psi-mi:upk1a_human(display_long)|uniprotkb:UPK1A(gene name)|psi-mi:UPK1A(display_short)|uniprotkb:TSPAN21(gene name synonym)|uniprotkb:Uroplakin Ia(gene name synonym)|uniprotkb:Tetraspanin-21(gene name synonym)	psi-mi:fimh_ecoli(display_long)|uniprotkb:fimH(gene name)|psi-mi:fimH(display_short)|uniprotkb:Protein FimH(gene name synonym)|uniprotkb:JW4283(locus name)|uniprotkb:b4320(locus name)	psi-mi:"MI:0892"(solid phase assay)	Hashimoto et al. (2017)	pubmed:28228557|imex:IM-26025	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-14032028|imex:IM-26025-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268372.1|refseq:NP_008931.1|ensembl:ENSG00000105668(gene)|ensembl:ENST00000222275(transcript)|ensembl:ENST00000617999(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034765	refseq:NP_418740.1|ensemblbacteria:AAC77276(transcript)|ensemblbacteria:b4320(gene)|ensemblbacteria:BAE78313(gene)|ensemblbacteria:BAE78313(transcript)|go:"GO:0005537"(mannose binding)|go:"GO:0007155"(cell adhesion)|go:"GO:0009289"(pilus)|go:"GO:0033644"(host cell membrane)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|interpro:IPR000259(Fimbrial protein)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR015243(FimH, mannose-binding)|interpro:IPR036937|rcsb pdb:1KIU|rcsb pdb:1KLF|rcsb pdb:1QUN|rcsb pdb:1TR7|rcsb pdb:1UWF|rcsb pdb:1ZE3|rcsb pdb:2VCO|rcsb pdb:3RFZ|rcsb pdb:3ZL1|rcsb pdb:3ZL2|rcsb pdb:4ATT|rcsb pdb:4AUJ|rcsb pdb:4AUU|rcsb pdb:4AUY|rcsb pdb:4AV0|rcsb pdb:4AV4|rcsb pdb:4AV5|rcsb pdb:4AVH|rcsb pdb:4AVI|rcsb pdb:4AVJ|rcsb pdb:4AVK|rcsb pdb:4CSS|rcsb pdb:4CST|rcsb pdb:4J3O|rcsb pdb:4LOV|rcsb pdb:4X50|rcsb pdb:4X5P|rcsb pdb:4X5Q|rcsb pdb:4X5R|rcsb pdb:4XO8|rcsb pdb:4XO9|rcsb pdb:4XOA|rcsb pdb:4XOB|rcsb pdb:5JCR|rcsb pdb:5L4T|rcsb pdb:5L4U|rcsb pdb:5L4V|rcsb pdb:5L4W|rcsb pdb:5L4X|rcsb pdb:5L4Y|rcsb pdb:5MCA|rcsb pdb:5MTS|rcsb pdb:5MUC|rcsb pdb:6E14|rcsb pdb:6E15|rcsb pdb:6G2R|rcsb pdb:6G2S|rcsb pdb:6GTX|rcsb pdb:6GTY|rcsb pdb:6YHW|rcsb pdb:7AYN|rcsb pdb:4XOD|rcsb pdb:5ABZ|rcsb pdb:5CGB|rcsb pdb:5F2F|rcsb pdb:5F3F|rcsb pdb:5FS5|rcsb pdb:5FWR|rcsb pdb:5FX3|rcsb pdb:5JCQ|refseq:WP_000832247.1|dip:DIP-9616N	-	-	-	figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/04/13	2017/04/13	rogid:/W9BzFoQXsagQQwLySUl280GnQk9606	rogid:5DDG/zwwZi4t597Dk1JZiEj5Leo83333	rigid:1Upbh9C/Vus2kb9KeRXu69PqV9c	false	flag tag:c-c	binding-associated region:1-181	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O00322	uniprotkb:P35247	intact:EBI-14031976|uniprotkb:Q3KNU5|uniprotkb:Q3KNU6|ensembl:ENSP00000222275|ensembl:ENSP00000483176	intact:EBI-11316157|uniprotkb:Q5T0M3|uniprotkb:Q6FH08|uniprotkb:Q86YK9|uniprotkb:Q8TCD8|uniprotkb:Q9UCJ2|uniprotkb:Q9UCJ3|ensembl:ENSP00000361366	psi-mi:upk1a_human(display_long)|uniprotkb:UPK1A(gene name)|psi-mi:UPK1A(display_short)|uniprotkb:TSPAN21(gene name synonym)|uniprotkb:Uroplakin Ia(gene name synonym)|uniprotkb:Tetraspanin-21(gene name synonym)	psi-mi:sftpd_human(display_long)|uniprotkb:SFTPD(gene name)|psi-mi:SFTPD(display_short)|uniprotkb:COLEC7(gene name synonym)|uniprotkb:PSPD(gene name synonym)|uniprotkb:SFTP4(gene name synonym)|uniprotkb:Collectin-7(gene name synonym)|uniprotkb:Lung surfactant protein D(gene name synonym)	psi-mi:"MI:0892"(solid phase assay)	Hashimoto et al. (2017)	pubmed:28228557|imex:IM-26025	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-14032034|imex:IM-26025-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268372.1|refseq:NP_008931.1|ensembl:ENSG00000105668(gene)|ensembl:ENST00000222275(transcript)|ensembl:ENST00000617999(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034765	refseq:NP_003010.4|refseq:XP_011538389.1|rcsb pdb:2GGU|rcsb pdb:2GGX|rcsb pdb:2ORJ|rcsb pdb:2ORK|rcsb pdb:2OS9|rcsb pdb:2RIA|rcsb pdb:2RIB|rcsb pdb:2RIC|rcsb pdb:2RID|rcsb pdb:2RIE|rcsb pdb:3DBZ|rcsb pdb:3G81|rcsb pdb:3G83|rcsb pdb:3G84|rcsb pdb:3IKN|rcsb pdb:3IKP|rcsb pdb:3IKQ|rcsb pdb:3IKR|rcsb pdb:4E52|rcsb pdb:4M17|rcsb pdb:4M18|rcsb pdb:5OXR|rcsb pdb:5OXS|reactome:R-HSA-166016|reactome:R-HSA-168179|reactome:R-HSA-198933|reactome:R-HSA-391160|reactome:R-HSA-5683826|reactome:R-HSA-5686938|reactome:R-HSA-5688849|reactome:R-HSA-5688890|ensembl:ENSG00000133661(gene)|ensembl:ENST00000372292(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0048286"(lung alveolus development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0052405"|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1905226"(regulation of adhesion of symbiont to host epithelial cell)|interpro:IPR001304(C-type lectin)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR015097(Lung surfactant protein D coiled-coil trimerisation)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033990|rcsb pdb:1B08|rcsb pdb:1M7L|rcsb pdb:1PW9|rcsb pdb:1PWB	-	-	-	figure legend:7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/04/13	2017/04/13	rogid:/W9BzFoQXsagQQwLySUl280GnQk9606	rogid:YVPGpA6rwjdTjpc67Y8V8EoFiWo9606	rigid:RBpzagyTa5FOJhaBE2DYb5MfQ+E	false	flag tag:c-c	-	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:O00322	uniprotkb:P08191	intact:EBI-14031976|uniprotkb:Q3KNU5|uniprotkb:Q3KNU6|ensembl:ENSP00000222275|ensembl:ENSP00000483176	intact:EBI-1028015|uniprotkb:Q2M5Z3|ensemblbacteria:AAC77276|ensemblbacteria:BAE78313	psi-mi:upk1a_human(display_long)|uniprotkb:UPK1A(gene name)|psi-mi:UPK1A(display_short)|uniprotkb:TSPAN21(gene name synonym)|uniprotkb:Uroplakin Ia(gene name synonym)|uniprotkb:Tetraspanin-21(gene name synonym)	psi-mi:fimh_ecoli(display_long)|uniprotkb:fimH(gene name)|psi-mi:fimH(display_short)|uniprotkb:Protein FimH(gene name synonym)|uniprotkb:JW4283(locus name)|uniprotkb:b4320(locus name)	psi-mi:"MI:0892"(solid phase assay)	Hashimoto et al. (2017)	pubmed:28228557|imex:IM-26025	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1335"(HPIDb)	intact:EBI-14032034|imex:IM-26025-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268372.1|refseq:NP_008931.1|ensembl:ENSG00000105668(gene)|ensembl:ENST00000222275(transcript)|ensembl:ENST00000617999(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120001"(apical plasma membrane urothelial plaque)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR034765	refseq:NP_418740.1|ensemblbacteria:AAC77276(transcript)|ensemblbacteria:b4320(gene)|ensemblbacteria:BAE78313(gene)|ensemblbacteria:BAE78313(transcript)|go:"GO:0005537"(mannose binding)|go:"GO:0007155"(cell adhesion)|go:"GO:0009289"(pilus)|go:"GO:0033644"(host cell membrane)|go:"GO:0043709"(cell adhesion involved in single-species biofilm formation)|interpro:IPR000259(Fimbrial protein)|interpro:IPR008966(Adhesion, bacterial)|interpro:IPR015243(FimH, mannose-binding)|interpro:IPR036937|rcsb pdb:1KIU|rcsb pdb:1KLF|rcsb pdb:1QUN|rcsb pdb:1TR7|rcsb pdb:1UWF|rcsb pdb:1ZE3|rcsb pdb:2VCO|rcsb pdb:3RFZ|rcsb pdb:3ZL1|rcsb pdb:3ZL2|rcsb pdb:4ATT|rcsb pdb:4AUJ|rcsb pdb:4AUU|rcsb pdb:4AUY|rcsb pdb:4AV0|rcsb pdb:4AV4|rcsb pdb:4AV5|rcsb pdb:4AVH|rcsb pdb:4AVI|rcsb pdb:4AVJ|rcsb pdb:4AVK|rcsb pdb:4CSS|rcsb pdb:4CST|rcsb pdb:4J3O|rcsb pdb:4LOV|rcsb pdb:4X50|rcsb pdb:4X5P|rcsb pdb:4X5Q|rcsb pdb:4X5R|rcsb pdb:4XO8|rcsb pdb:4XO9|rcsb pdb:4XOA|rcsb pdb:4XOB|rcsb pdb:5JCR|rcsb pdb:5L4T|rcsb pdb:5L4U|rcsb pdb:5L4V|rcsb pdb:5L4W|rcsb pdb:5L4X|rcsb pdb:5L4Y|rcsb pdb:5MCA|rcsb pdb:5MTS|rcsb pdb:5MUC|rcsb pdb:6E14|rcsb pdb:6E15|rcsb pdb:6G2R|rcsb pdb:6G2S|rcsb pdb:6GTX|rcsb pdb:6GTY|rcsb pdb:6YHW|rcsb pdb:7AYN|rcsb pdb:4XOD|rcsb pdb:5ABZ|rcsb pdb:5CGB|rcsb pdb:5F2F|rcsb pdb:5F3F|rcsb pdb:5FS5|rcsb pdb:5FWR|rcsb pdb:5FX3|rcsb pdb:5JCQ|refseq:WP_000832247.1|dip:DIP-9616N	-	-	-	figure legend:7D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/04/13	2017/04/13	rogid:/W9BzFoQXsagQQwLySUl280GnQk9606	rogid:5DDG/zwwZi4t597Dk1JZiEj5Leo83333	rigid:RBpzagyTa5FOJhaBE2DYb5MfQ+E	false	flag tag:c-c	binding-associated region:1-181|his tag:?-?	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)